|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.
Reaction Locations: periplasm (sensu Gram-negative Bacteria)
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: phospholipase A2
Enzyme Commission Synonyms: lecithinase A, phosphatidase, phosphatidolipase, phospholipase A
Enzyme Commission Summary:
Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position. Requires Ca2+.
Doery61: Doery HM, Pearson JE (1961). "Haemolysins in venoms of Australian snakes. Observations on the haemolysins of the venoms of some Australian snakes and the separation of phospholipase A from the venom of Pseudechis porphyriacus." Biochem J 78;820-7. PMID: 13723433
Hanahan60: Hanahan DJ, Brockerheff H, Barron EJ (1960). "The site of attack of phospholipase (lecithinase) A on lecithin: a re-evaluation. Position of fatty acids on lecithins and triglycerides." J Biol Chem 235;1917-23. PMID: 14399412
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