Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 6.2.1.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.2.1.5

Enzymes and Genes:
succinyl-CoA synthetase Inferred from experiment : sucD , sucC

In Pathway: TCA cycle I (prokaryotic)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: succinate—CoA ligase (ADP-forming)

Enzyme Commission Synonyms: succinyl-CoA synθse (ADP-forming), succinic thiokinase, succinate thiokinase, succinyl-CoA synθse, succinyl coenzyme A synθse (adenosine diphosphate-forming), succinyl coenzyme A synθse, A-STK (adenin nucleotide-linked succinate thiokinase), STK, A-SCS

Summary:
SUBREACTIONS: Enz + ATP = Enz-P + ADP Enz-P + succinate = Enz.succinylP Enz.succinylP + CoA = Enz + Pi + succinylCoa

Citations: [KAUFMAN55, KAUFMAN55a]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:6.2.1.5 , ENZYME:EC:6.2.1.5 , IUBMB-ExplorEnz:EC:6.2.1.5


References

KAUFMAN55: KAUFMAN S, ALIVISATOS SG (1955). "Purification and properties of the phosphorylating enzyme from spinach." J Biol Chem 216(1);141-52. PMID: 13252014

KAUFMAN55a: KAUFMAN S (1955). "Studies on the mechanism of the reaction catalyzed by the phosphorylating enzyme." J Biol Chem 216(1);153-64. PMID: 13252015


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13B.