Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
succinyl-CoA synthetase Inferred from experiment : sucD , sucC

In Pathway: TCA cycle I (prokaryotic)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: succinate—CoA ligase (ADP-forming)

Enzyme Commission Synonyms: succinyl-CoA synθse (ADP-forming), succinic thiokinase, succinate thiokinase, succinyl-CoA synθse, succinyl coenzyme A synθse (adenosine diphosphate-forming), succinyl coenzyme A synθse, A-STK (adenin nucleotide-linked succinate thiokinase), STK, A-SCS

SUBREACTIONS: Enz + ATP = Enz-P + ADP Enz-P + succinate = Enz.succinylP Enz.succinylP + CoA = Enz + Pi + succinylCoa

Citations: [KAUFMAN55, KAUFMAN55a]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


KAUFMAN55: KAUFMAN S, ALIVISATOS SG (1955). "Purification and properties of the phosphorylating enzyme from spinach." J Biol Chem 216(1);141-52. PMID: 13252014

KAUFMAN55a: KAUFMAN S (1955). "Studies on the mechanism of the reaction catalyzed by the phosphorylating enzyme." J Biol Chem 216(1);153-64. PMID: 13252015

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Mar 31, 2015, BIOCYC13B.