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Escherichia coli K-12 substr. MG1655 Reaction: 3.6.3.12


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsTransport Energised by P-P Bond Hydrolysis
Reactions Classified By Conversion TypeSimple ReactionsTransport ReactionsTransport Energised by P-P Bond Hydrolysis
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 3.6.3.12

Transporters and Genes:
K+ transporting ATPaseInferred from experiment: kdpF, kdpA, kdpB, kdpC

Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.

Transport reaction diagram

Reaction Locations: inner membrane (sensu Gram-negative Bacteria)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: K+-transporting ATPase

Enzyme Commission Synonyms: K+-translocating Kdp-ATPase, multi-subunit K+-transport ATPase

Enzyme Commission Summary:
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A bacterial enzyme of di(heterotetrameric) structure that is involved in K+ import. The probable stoichiometry is one ion per ATP hydrolysed.

Citations: [Siebers89, Gassel98]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:3.6.3.12, ENZYME:EC:3.6.3.12, IUBMB-ExplorEnz:EC:3.6.3.12


References

Gassel98: Gassel M, Siebers A, Epstein W, Altendorf K (1998). "Assembly of the Kdp complex, the multi-subunit K+-transport ATPase of Escherichia coli." Biochim Biophys Acta 1998;1415(1);77-84. PMID: 9858692

Siebers89: Siebers A, Altendorf K (1989). "Characterization of the phosphorylated intermediate of the K+-translocating Kdp-ATPase from Escherichia coli." J Biol Chem 1989;264(10);5831-8. PMID: 2522440


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun Feb 7, 2016, biocyc11.