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Escherichia coli K-12 substr. MG1655 Reaction: 3.6.3.12

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions Transport Energised by P-P Bond Hydrolysis
Reactions Classified By Conversion Type Simple Reactions Transport Reactions Transport Energised by P-P Bond Hydrolysis
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.6.3.12

Transporters and Genes:
K+ transporting ATPase Inferred from experiment : kdpF , kdpA , kdpB , kdpC

Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.

Transport reaction diagram

Reaction Locations: inner membrane (sensu Gram-negative Bacteria)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: K+-transporting ATPase

Enzyme Commission Synonyms: K+-translocating Kdp-ATPase, multi-subunit K+-transport ATPase

Enzyme Commission Summary:
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A bacterial enzyme of di(heterotetrameric) structure that is involved in K+ import. The probable stoichiometry is one ion per ATP hydrolysed.

Citations: [Siebers89, Gassel98]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:3.6.3.12 , ENZYME:EC:3.6.3.12 , IUBMB-ExplorEnz:EC:3.6.3.12


References

Gassel98: Gassel M, Siebers A, Epstein W, Altendorf K (1998). "Assembly of the Kdp complex, the multi-subunit K+-transport ATPase of Escherichia coli." Biochim Biophys Acta 1998;1415(1);77-84. PMID: 9858692

Siebers89: Siebers A, Altendorf K (1989). "Characterization of the phosphorylated intermediate of the K+-translocating Kdp-ATPase from Escherichia coli." J Biol Chem 1989;264(10);5831-8. PMID: 2522440


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Sat Aug 29, 2015, biocyc14.