|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Transport Reactions → Transport Reactions of Unknown Mechanism|
|Reactions Classified By Substrate → Small-Molecule Reactions|
Reaction Locations: extracellular space/cytosol
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
The activity of enterochelin esterase results in the hydrolysis of enterobactin into the linear trimer, dimer and monomer of 2,3 dihydroxybenzoyl serine. An E.coli entS mutant is unable to secrete enterobactin efficiently but does have elevated levels of enterobactin breakdown products in the culture medium. Dihydroxybenzoyl serine is able to stimulate the growth of E.coli under iron limiting conditions by acting as a siderophore [Furrer02].
Furrer02: Furrer JL, Sanders DN, Hook-Barnard IG, McIntosh MA (2002). "Export of the siderophore enterobactin in Escherichia coli: involvement of a 43 kDa membrane exporter." Mol Microbiol 44(5);1225-34. PMID: 12068807
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