Escherichia coli K-12 substr. MG1655 Reaction: transport of 5-(2-hydroxyethyl)-4-methylthiazole

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsTransport ReactionsTransport Reactions of Unknown Mechanism
Reactions Classified By SubstrateSmall-Molecule Reactions

Transport reaction diagram

Reaction Locations: inner membrane (sensu Gram-negative Bacteria)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Uptake of labelled 4-methyl-5-(β-hydroxyethyl) thiazole (THZ) by intact E. coli cells has been demonstrated. A 50% inhibition of uptake is observed when cells are treated with 1mM N-ethylmaleimide [Yamasaki73].

Created 13-Apr-2011 by Mackie A, Macquarie University


Yamasaki73: Yamasaki H, Sanemori H, Yamada K, Kawasaki T (1973). "Hydroxyethylthiazole uptake in Escherichia coli: general properties and relationship between uptake and thiamine biosynthesis." J Bacteriol 116(3);1280-6. PMID: 4584810

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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