Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
trans-2-enoyl-CoA reductase

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: trans-2-enoyl-CoA reductase (NADPH)

Enzyme Commission Synonyms: NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, trans-2-enoyl-CoA reductase (NADPH2)

This reaction may participate in the chain elongation or degradation of fatty acids.

Enzyme Commission Summary:
Not identical with EC, cis-2-enoyl-CoA reductase (NADPH) [cf. EC acyl-CoA dehydrogenase (NADP+)].

Citations: [Mizugaki82]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Mizugaki82: Mizugaki M, Nishimaki T, Shiraishi T, Kawaguchi A, Okuda S, Yamanaka H (1982). "Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli." J Biochem (Tokyo) 1982;92(5);1649-54. PMID: 6759504

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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