Escherichia coli K-12 substr. MG1655 Enzyme: dihydroneopterin monophosphate dephosphorylase

No enzyme that specifically catalyzes this phosphatase reaction has been identified. It is thought that several non-specific phosphatases may catalyze this step [Suzuki74].

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Last-Curated ? 12-Jul-2011 by Keseler I , SRI International

Enzymatic reaction of: dihydroneopterin monophosphate dephosphorylase

EC Number: 3.6.1.-

7,8-dihydroneopterin 3'-phosphate + H2O <=> 7,8-dihydroneopterin + phosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is favored in the direction shown.

In Pathways: superpathway of chorismate metabolism , superpathway of tetrahydrofolate biosynthesis , 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I


Suzuki74: Suzuki Y, Brown GM (1974). "The biosynthesis of folic acid. XII. Purification and properties of dihydroneopterin triphosphate pyrophosphohydrolase." J Biol Chem 1974;249(8);2405-10. PMID: 4362677

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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