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Escherichia coli K-12 substr. MG1655 Polypeptide: predicted inner membrane protein

Gene: ybjC Accession Numbers: EG12842 (EcoCyc), b0850, ECK0841

Regulation Summary Diagram: ?

Regulation summary diagram for ybjC

The nfsA and ybjC genes are co-transcribed [Paterson02]. Transcription is induced by paraquat and appears to be directly regulated by SoxS [Paterson02].

Gene Citations: [Kang89]

Map Position: [890,136 -> 890,423] (19.19 centisomes, 69°)
Length: 288 bp / 95 aa

Molecular Weight of Polypeptide: 10.521 kD (from nucleotide sequence)

Unification Links: ASAP:ABE-0002898 , EchoBASE:EB2691 , EcoGene:EG12842 , EcoliWiki:b0850 , OU-Microarray:b0850 , PortEco:ybjC , Protein Model Portal:P46119 , RefSeq:NP_415371 , RegulonDB:EG12842 , String:511145.b0850 , UniProt:P46119

Relationship Links: InterPro:IN-FAMILY:IPR010815 , Pfam:IN-FAMILY:PF07214

Genetic Regulation Schematic: ?

Genetic regulation schematic for ybjC

Gene Class: ORFs Conserved-Hypothetical-ORFs

Essentiality data for ybjC knockouts: ?

Growth Medium Growth? T (°C) O2 pH Osm/L Growth Observations
LB Lennox Yes 37 Aerobic 7   Yes [Baba06, Comment 1]
M9 medium with 1% glycerol Yes 37 Aerobic 7.2 0.35 Yes [Joyce06, Comment 2]
MOPS medium with 0.4% glucose Yes 37 Aerobic 7.2 0.22 Yes [Baba06, Comment 1]

Last-Curated ? 11-Apr-2006 by Keseler I , SRI International

Gene Local Context (not to scale): ?

Gene local context diagram

Transcription Units:

Transcription-unit diagram

Transcription-unit diagram

Transcription-unit diagram

Transcription-unit diagram


Peter D. Karp on Thu Jan 16, 2003:
Predicted gene function revised as a result of E. coli genome reannotation by Serres et al. [Serres01 ].
10/20/97 Gene b0850 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG12842; confirmed by SwissProt match.


Baba06: Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006). "Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection." Mol Syst Biol 2;2006.0008. PMID: 16738554

Joyce06: Joyce AR, Reed JL, White A, Edwards R, Osterman A, Baba T, Mori H, Lesely SA, Palsson BO, Agarwalla S (2006). "Experimental and computational assessment of conditionally essential genes in Escherichia coli." J Bacteriol 188(23);8259-71. PMID: 17012394

Kang89: Kang WK, Icho T, Isono S, Kitakawa M, Isono K (1989). "Characterization of the gene rimK responsible for the addition of glutamic acid residues to the C-terminus of ribosomal protein S6 in Escherichia coli K12." Mol Gen Genet 217(2-3);281-8. PMID: 2570347

Paterson02: Paterson ES, Boucher SE, Lambert IB (2002). "Regulation of the nfsA Gene in Escherichia coli by SoxS." J Bacteriol 184(1);51-8. PMID: 11741843

Serres01: Serres MH, Gopal S, Nahum LA, Liang P, Gaasterland T, Riley M (2001). "A functional update of the Escherichia coli K-12 genome." Genome Biol 2(9);RESEARCH0035. PMID: 11574054

Other References Related to Gene Regulation

Benov02: Benov L, Fridovich I (2002). "Induction of the soxRS regulon of Escherichia coli by glycolaldehyde." Arch Biochem Biophys 407(1);45-8. PMID: 12392714

Martin02: Martin RG, Rosner JL (2002). "Genomics of the marA/soxS/rob regulon of Escherichia coli: identification of directly activated promoters by application of molecular genetics and informatics to microarray data." Mol Microbiol 44(6);1611-24. PMID: 12067348

Martin11: Martin RG, Rosner JL (2011). "Promoter discrimination at class I MarA regulon promoters mediated by glutamic acid 89 of the MarA transcriptional activator of Escherichia coli." J Bacteriol 193(2);506-15. PMID: 21097628

Tao97: Tao K (1997). "oxyR-dependent induction of Escherichia coli grx gene expression by peroxide stress." J Bacteriol 1997;179(18);5967-70. PMID: 9294462

Zheng01a: Zheng M, Wang X, Templeton LJ, Smulski DR, LaRossa RA, Storz G (2001). "DNA microarray-mediated transcriptional profiling of the Escherichia coli response to hydrogen peroxide." J Bacteriol 183(15);4562-70. PMID: 11443091

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Sep 1, 2015, biocyc13.