Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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Homo sapiens Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: 4-tyrosol + NAD+ = (4-hydroxyphenyl)acetaldehyde + NADH + H+ ,
1.1.1.1: a primary alcohol + NAD+ = an aldehyde + NADH + H+ ,
1.1.1.1: methionol + NAD+ = 3-methylthiopropanal + NADH + H+ ,
1.1.1.1: indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ ,
1.1.1.1: isobutanol + NAD+ ↔ isobutanal + NADH + H+ ,
1.1.1.1: phytol + NAD+ → phytenal + NADH + H+ ,
1.1.1.1: 3-methoxy-4-hydroxyphenylglycol + NAD+ ↔ 3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 2-methylbutanol + NAD+ = 2-methylbutanal + NADH + H+ ,
1.1.1.1: n-propanol + NAD+ = propanal + NADH + H+ ,
1.1.1.1: 2-phenylethanol + NAD+ = phenylacetaldehyde + NADH + H+ ,
1.1.1.1: 3,4-dihydroxyphenylglycol + NAD+ ← 3,4-dihydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 3-methylbutanol + NAD+ ↔ 3-methylbutanal + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: 5-hydroxytryptophol + NAD+ ← 5-hydroxyindole acetaldehyde + NADH + H+ ,
1.1.1.1: a secondary alcohol + NAD+ = a ketone + NADH + H+ ,
1.1.1.2: ethanol + NADP+ = acetaldehyde + NADPH + H+ ,
1.1.1.2: an alcohol + NADP+ = an aldehyde + NADPH + H+ ,
1.1.1.2: indole acetaldehyde + NADPH + H+ → indole-3-ethanol + NADP+ ,
1.1.1.8: sn-glycerol 3-phosphate + NAD+ ↔ dihydroxyacetone phosphate + NADH + H+ ,
1.1.1.9: xylitol + NAD+ = D-xylulose + NADH + H+ ,
1.1.1.10: xylitol + NADP+ ↔ L-xylulose + NADPH + H+ ,
1.1.1.14: D-sorbitol + NAD+ → keto-D-fructose + NADH + H+ ,
1.1.1.14: L-iditol + NAD+ = keto-L-sorbose + NADH + H+ ,
1.1.1.19: L-gulonate + NADP+aldehydo-D-glucuronate + NADPH + H+ ,
1.1.1.21: galactitol + NADP+ ↔ β-D-galactose + NADPH + H+ ,
1.1.1.21: L-arabitol + NADP+ ↔ L-arabinopyranose + NADPH + H+ ,
1.1.1.21: a sugar alcohol + NAD(P)+ = an aldose + NAD(P)H + H+ ,
1.1.1.22: UDP-α-D-glucose + 2 NAD+ + H2O → UDP-α-D-glucuronate + 2 NADH + 3 H+ ,
1.1.1.27: (S)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.29: D-glycerate + NAD+ = hydroxypyruvate + NADH + H+ ,
1.1.1.30: (R)-3-hydroxybutanoate + NAD+ ↔ acetoacetate + NADH + H+ ,
1.1.1.31: (S)-3-hydroxy-isobutanoate + NAD+ → (S)-methylmalonate-semialdehyde + NADH + H+ ,
1.1.1.34: (R)-mevalonate + coenzyme A + 2 NADP+ ← (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ ,
1.1.1.35: (S)-3-hydroxybutanoyl-CoA + NAD+ ↔ acetoacetyl-CoA + NADH + H+ ,
1.1.1.35: (S)-3-hydroxydecanoyl-CoA + NAD+ = 3-oxodecanoyl-CoA + NADH + H+ ,
1.1.1.35: a (3S)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.36: a (3R)-3-hydroxyacyl-CoA + NADP+ = a 3-oxoacyl-CoA + NADPH + H+ ,
1.1.1.36: (R)-3-hydroxybutanoyl-CoA + NADP+ = acetoacetyl-CoA + NADPH + H+ ,
1.1.1.36: (R)-3-hydroxyvaleryl-CoA + NADP+ = β-ketovaleryl-CoA + NADPH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ = pyruvate + CO2 + NADH ,
1.1.1.40: (S)-malate + NADP+ = CO2 + pyruvate + NADPH ,
1.1.1.41: D-threo-isocitrate[mitochondrial lumen] + NAD+[mitochondrial lumen] → CO2[mitochondrial lumen] + 2-oxoglutarate[mitochondrial lumen] + NADH[mitochondrial lumen] ,
1.1.1.42: D-threo-isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.45: L-gulonate + NAD+ → 3-keto-L-gulonate + NADH + H+ ,
1.1.1.47: D-glucopyranose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+ ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.50/1.1.1.209/1.1.1.213: androsterone + NAD(P)+ = 5α-androstane-3,17-dione + NAD(P)H + H+ ,
1.1.1.51: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+ ,
1.1.1.62: 17β-estradiol + NAD(P)+ → estrone + NAD(P)H + H+ ,
1.1.1.64: testosterone + NADP+ ← androst-4-ene-3,17-dione + NADPH + H+ ,
1.1.1.71: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ ,
1.1.1.77: (R)-propane-1,2-diol + NAD+ ← (R)-lactaldehyde + NADH + H+ ,
1.1.1.78: (R)-lactaldehyde + NAD+ ← methylglyoxal + NADH + H+ ,
1.1.1.79: glycolate + NADP+ = glyoxylate + NADPH + H+ ,
1.1.1.80: isopropanol + NADP+ → acetone + NADPH + H+ ,
1.1.1.81: D-glycerate + NAD(P)+ = hydroxypyruvate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.102: sphinganine + NADP+ ← 3-dehydrosphinganine + NADPH + H+ ,
1.1.1.105: all-trans-retinol + NAD+all-trans-retinal + NADH + H+ ,
1.1.1.105: an all-trans retinol-[cellular-retinol-binding-protein] + NAD+ → an all-trans retinal-[cellular-retinol-binding-protein] + NADH + H+ ,
1.1.1.112: 1-indanol + NAD(P)+ = indanone + NAD(P)H + H+ ,
1.1.1.141: prostaglandin E2 + NAD+ = (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprosta-13-enoate + NADH + H+ ,
1.1.1.145: 17-α-hydroxypregnenolone + NAD+ = pregn-5-ene-3,20-dione-17-ol + NADH + H+ ,
1.1.1.145: pregnenolone + NAD+ → pregn-5-ene-3,20-dione + NADH + H+ ,
1.1.1.145: dehydroepiandrosterone + NAD+ → 5-androstene-3,17-dione + NADH + H+ ,
1.1.1.145: a 3β-hydroxy-δ5-steroid + NAD+ = a 3-oxo-δ5-steroid + NADH + H+ ,
1.1.1.146: an 11-β-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+ ,
1.1.1.149: (20S)-17,20-dihydroxypregn-4-en-3-one + NAD(P)+ = 17-α-hydroxyprogesterone + NAD(P)H + H+ ,
1.1.1.153: L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP+ ← 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ ,
1.1.1.153: L-erythro-7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+ ,
1.1.1.170: 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + NAD(P)+ = CO2 + 4α-methyl-5α-cholest-7-en-3-one + NAD(P)H ,
1.1.1.170: 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ → 5α-cholesta-8,24-dien-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ → 4α-methyl-5α-cholesta-8-en-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-5α-cholesta-8-en-3β-ol + NAD(P)+ → 5α-cholesta-8-en-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ → 3-dehydro-4-methylzymosterol + CO2 + NAD(P)H ,
1.1.1.178: 2-methyl-3-hydroxybutyryl-CoA + NAD+ → 2-methylacetoacetyl-CoA + NADH + H+ ,
1.1.1.179: a D-xylopyranose + NADP+ ↔ D-xylonolactone + NADPH + H+ ,
1.1.1.181: 7α-hydroxycholesterol + NAD+ → 7α-hydroxycholest-4-en-3-one + NADH + H+ ,
1.1.1.184: a secondary alcohol + NADP+ = a ketone + NADPH + H+ ,
1.1.1.188: prostaglandin F + NADP+ = prostaglandin D2 + NADPH + H+ ,
1.1.1.189: prostaglandin F + NADP+ = prostaglandin E2 + NADPH + H+ ,
1.1.1.197: (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoate + NADP+ = (13E)-11-α-hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.210: 5-α-androstan-3β,17β-diol + NADP+ = 5-α-dihydrotestosterone + NADPH + H+ ,
1.1.1.211: a long-chain (3S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.213: 5β-cholestane-3α,7α-diol + NAD(P)+ ← 7α-hydroxy-5β-cholestan-3-one + NAD(P)H + H+ ,
1.1.1.213: 5β-cholestane-3α,7α,12α-triol + NAD(P)+ ← 7α,12α-dihydroxy-5β-cholestan-3-one + NAD(P)H + H+ ,
1.1.1.213: allopregnanolone + NAD(P)+ ↔ 5-α-pregnane-3,20-dione + NAD(P)H + H+ ,
1.1.1.213: 5-α-androstan-3α,17β-diol + NAD(P)+ = 5-α-dihydrotestosterone + NAD(P)H + H+ ,
1.1.1.216: (2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ ,
1.1.1.218: morphine + NAD(P)+ ← morphinone + NAD(P)H + H+ ,
1.1.1.225: chlordecone alcohol + NADP+ = chlordecone + NADPH + H+ ,
1.1.1.237: 3-(4-hydroxyphenyl)lactate + NAD+ ← 4-hydroxyphenylpyruvate + NADH + H+ ,
1.1.1.239: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH + H+ ,
1.1.1.247: codeine + NADP+ ← codeinone + NADPH + H+ ,
1.1.1.248: salutaridinol + NADP+ ← salutaridine + NADPH + H+ ,
1.1.1.263: 1,5-anhydro-D-glucitol + NADP+ ← 1,5-anhydro-D-fructose + NADPH + H+ ,
1.1.1.270: zymosterol + NADP+ ← 5α-cholesta-8,24-dien-3-one + NADPH + H+ ,
1.1.1.270: zymostenol + NADP+ ← 5α-cholesta-8-en-3-one + NADPH + H+ ,
1.1.1.270: 4α-methyl-zymosterol + NADP+ ← 3-dehydro-4-methylzymosterol + NADPH + H+ ,
1.1.1.270: 4α-methyl-5α-cholest-7-en-3β-ol + NADP+ = 4α-methyl-5α-cholest-7-en-3-one + NADPH + H+ ,
1.1.1.270: 4α-methyl-cholesta-8-enol + NADP+ ← 4α-methyl-5α-cholesta-8-en-3-one + NADPH + H+ ,
1.1.1.271: GDP-β-L-fucose + NADP+ ← GDP-4-dehydro-α-D-rhamnose + NADPH + H+ ,
1.1.1.278: allopregnanolone + NADP+ = 5-α-pregnane-3,20-dione + NADPH + H+ ,
1.1.1.284: S-hydroxymethylglutathione + NAD(P)+S-formylglutathione + NAD(P)H + H+ ,
1.1.1.300: all-trans-retinol + NADP+all-trans-retinal + NADPH + H+ ,
1.1.1.315: an 11-cis-retinol-[retinal-binding protein] + NAD+ → an 11-cis-retinal-[retinal-binding protein] + NADH + H+ ,
1.1.1.330: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain oxoacyl-CoA + NADPH + H+ ,
1.1.1.-: acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
1.1.1.-: 13-cis-retinol + NAD+ → 13-cis-retinal + NADH + H+ ,
1.1.1.-: 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: trans-2-pentenol + NADP+ = trans-2-pentenal + NADPH + H+ ,
1.1.1.-: a (3R)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.-: n-butanol + NAD+ ← butanal + NADH + H+ ,
1.1.1.-: choloyl-CoA + NAD(P)+ = 3-oxo-cholyl-CoA + NAD(P)H + H+ ,
1.1.1.-: 11-cis-retinol + NADP+ = 11-cis-retinal + NADPH + H+ ,
1.1.1.-: (6E)-8-hydroxygeranial + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ,
1.1.1.-: (R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: cholate + NAD+ = 3-dehydrocholate + NADH + H+ ,
1.1.1.-: trans-2-hexenol + NADP+ = trans-2-hexenal + NADPH + H+ ,
1.1.1.-: n-butanol + NADP+ = butanal + NADPH + H+ ,
1.1.1.-: 9-cis-retinol + NAD+ = 9-cis-retinal + NADH + H+ ,
1.1.1.-: (6E)-8-oxogeraniol + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ,
1.1.3.15: an (S)-2-hydroxyacid + oxygen → hydrogen peroxide + a 2-oxo carboxylate ,
1.1.3.-: glycolate + oxygen → glyoxylate + hydrogen peroxide ,
1.1.5.3: sn-glycerol 3-phosphate[mitochondrial intermembrane space] + an ubiquinone[mitochondrial inner membrane] → dihydroxyacetone phosphate[mitochondrial intermembrane space] + an ubiquinol[mitochondrial inner membrane] ,
1.1.5.-: (R)-lactate + an ubiquinone[inner membrane] → pyruvate + an ubiquinol[inner membrane] ,
1.1.99.1: choline + an oxidized electron acceptor → betaine aldehyde + a reduced electron acceptor ,
1.1.99.2: (S)-2-hydroxyglutarate + an oxidized electron acceptor = 2-oxoglutarate + a reduced electron acceptor ,
1.1.99.14: glycolate + an oxidized electron acceptor = glyoxylate + a reduced electron acceptor ,
1.1.99.24: (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate ,
1.1.-.-: allopregnanolone[cytosol] + NAD+[cytosol] → 5-α-pregnane-3,20-dione[cytosol] + NADH[cytosol] + H+[cytosol] ,
1.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O → an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: phytenal + NAD+ + H2O → phytenate + NADH + 2 H+ ,
1.2.1.3: 3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O → 3,4-dihydroxyphenylacetate + NADH + 2 H+ ,
1.2.1.3: 5-hydroxyindole acetaldehyde + NAD+ + H2O → 5-hydroxyindole acetate + NADH + 2 H+ ,
1.2.1.3: a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O → a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+ ,
1.2.1.3: 3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O → 3,4-dihydroxymandelate + NADH + 2 H+ ,
1.2.1.3: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ ,
1.2.1.3: a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+ ,
1.2.1.3: octanal + NAD+ + H2O = octanoate + NADH + 2 H+ ,
1.2.1.3: imidazole acetaldehyde + NAD+ + H2O → 4-imidazoleacetate + NADH + 2 H+ ,
1.2.1.3: 3-methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O → vanillyl mandelate + NADH + 2 H+ ,
1.2.1.3: 4-acetamidobutanal + NAD+ + H2O → 4-acetamidobutanoate + NADH + 2 H+ ,
1.2.1.3: indole acetaldehyde + NAD+ + H2O → indole-3-acetate + NADH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + 2 H+ ,
1.2.1.5: an aldehyde + NAD(P)+ + H2O = a carboxylate + NAD(P)H + 2 H+ ,
1.2.1.5: indole acetaldehyde + NAD(P)+ + H2O = indole-3-acetate + NAD(P)H + 2 H+ ,
1.2.1.8: betaine aldehyde + NAD+ + H2O → glycine betaine + NADH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ → acetyl-CoA + NADH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.18: malonate semialdehyde + coenzyme A + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H ,
1.2.1.19: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+ ,
1.2.1.22: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+ ,
1.2.1.24: succinate semialdehyde + NAD+ + H2O → succinate + NADH + 2 H+ ,
1.2.1.25: 3-methyl-2-oxobutanoate + coenzyme A + NAD+ → isobutanoyl-CoA + CO2 + NADH ,
1.2.1.27: (S)-methylmalonate-semialdehyde + coenzyme A + NAD+ + H2O → propanoyl-CoA + hydrogen carbonate + NADH + H+ ,
1.2.1.31: (S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O → L-2-aminoadipate + NAD(P)H + 2 H+ ,
1.2.1.32: 2-aminomuconate 6-semialdehyde + NAD+ + H2O → 2-aminomuconate + NADH + 2 H+ ,
1.2.1.36: an all-trans retinal-[cellular-retinol-binding-protein] + NAD+ + H2O → all-trans-retinoate + a cellular-retinol-binding protein + NADH + H+ ,
1.2.1.36: all-trans-retinal + NAD+ + H2O = all-trans-retinoate + NADH + 2 H+ ,
1.2.1.39: phenylacetaldehyde + NAD+ + H2O → phenylacetate + NADH + 2 H+ ,
1.2.1.41: L-glutamate-5-semialdehyde[mitochondrial lumen] + NADP+[mitochondrial lumen] + phosphate[mitochondrial lumen] ← γ-L-glutamyl 5-phosphate[mitochondrial lumen] + NADPH[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.2.1.42: palmitaldehyde + coenzyme A + NAD+ = palmitoyl-CoA + NADH + H+ ,
1.2.1.47: 4-trimethylammoniobutanal + NAD+ + H2O → γ-butyrobetaine + NADH + 2 H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.84: a long-chain acyl-CoA + 2 NADPH + 2 H+ = a long-chain alcohol + coenzyme A + 2 NADP+ ,
1.2.1.88: L-glutamate-5-semialdehyde + NAD+ + H2O → L-glutamate + NADH + 2 H+ ,
1.2.1.-: (S)-3-methyl-2-oxopentanoate + coenzyme A + NAD+ → 2-methylbutanoyl-CoA + CO2 + NADH ,
1.2.1.-: 4-methyl-2-oxopentanoate + coenzyme A + NAD+ → isovaleryl-CoA + CO2 + NADH ,
1.2.1.-: pyruvate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + NAD+[mitochondrial lumen] = acetyl-CoA[mitochondrial lumen] + CO2[mitochondrial lumen] + NADH[mitochondrial lumen] ,
1.2.1.-: (S)-lactaldehyde + NADP+ + H2O = (S)-lactate + NADPH + 2 H+ ,
1.2.1.-: (S)-2-amino-6-oxohexanoate + NAD+ + H2O = L-2-aminoadipate + NADH + 2 H+ ,
1.2.1.-: L-4-hydroxyglutamate semialdehyde + NAD+ + H2O → erythro-4-hydroxy-L-glutamate + NADH + 2 H+ ,
1.2.1.-: malonate semialdehyde + coenzyme A + NAD+ = acetyl-CoA + CO2 + NADH ,
1.2.1.-: (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD+ + 2 H2O = L-2-aminoadipate + NADH + H+ ,
1.2.1.-: apo-4'-lycopenal + NAD(P)+ + H2O = apo-4'-lycopenoate + NADPH + H+ ,
1.2.1.-: malonate semialdehyde + coenzyme A + NADP+ = acetyl-CoA + CO2 + NADPH ,
1.2.3.1: acetaldehyde + oxygen + H2O → acetate + hydrogen peroxide + H+ ,
1.2.3.1: heptanal + oxygen + H2O → heptanoate + hydrogen peroxide + H+ ,
1.2.3.1: all-trans-retinal + H2O + oxygen → all-trans-retinoate + hydrogen peroxide + H+ ,
1.2.3.1: geranial + oxygen + H2O → geranate + hydrogen peroxide + H+ ,
1.2.3.1: an aldehyde + oxygen + H2O → a carboxylate + hydrogen peroxide + H+ ,
1.2.3.-: nicotine-Δ1'5'-iminium ion + oxygen + H2O → cotinine + hydrogen peroxide + H+ ,
1.2.99.7: an aldehyde + FAD + H2O = a carboxylate + FADH2 ,
1.3.1.2: 5,6-dihydrouracil + NADP+ ← uracil + NADPH + H+ ,
1.3.1.2: 5,6-dihydrothymine + NADP+ ← thymine + NADPH + H+ ,
1.3.1.3: 5β-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ ,
1.3.1.3: 7α-hydroxycholest-4-en-3-one + NADPH + H+ → 7α-hydroxy-5β-cholestan-3-one + NADP+ ,
1.3.1.3: 4,5β-dihydrocortisone + NADP+ = cortisone + NADPH + H+ ,
1.3.1.3: 7α,12α-dihydroxycholest-4-en-3-one + NADPH + H+ → 7α,12α-dihydroxy-5β-cholestan-3-one + NADP+ ,
1.3.1.14: (S)-dihydroorotate + NAD+ = orotate + NADH + H+ ,
1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+ ,
1.3.1.21: cholesterol + NADP+ ← 7-dehydrocholesterol + NADPH + H+ ,
1.3.1.21: desmosterol + NADP+ ← 7-dehydrodesmosterol + NADPH + H+ ,
1.3.1.22: 4,5α-dihydrocortisone + NADP+ = cortisone + NADPH + H+ ,
1.3.1.22: a 3-oxo-5-α-steroid + NADP+ = a 3-oxo-Δ4-steroid + NADPH + H+ ,
1.3.1.22: 5-α-dihydrotestosterone + NADP+ ← testosterone + NADPH + H+ ,
1.3.1.22: 5α-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ ,
1.3.1.22: 5-α-pregnane-3,20-dione + NADP+ ← progesterone + NADPH + H+ ,
1.3.1.24: bilirubin + NAD(P)+ ← biliverdin-IX-α + NAD(P)H + H+ ,
1.3.1.27: palmitaldehyde + NADP+ ← 2-trans-hexadecenal + NADPH + H+ ,
1.3.1.34: trans-Δ2-decenoyl-CoA + NADP+ = trans-Δ2, cis-Δ4-decadienoyl-CoA + NADPH + H+ ,
1.3.1.34: a 2-trans-4-cis-dienoyl-CoA + NADPH = a trans-3-enoyl-CoA + NADP+ + H+ ,
1.3.1.38: phytenoyl-CoA + NADPH + H+ → phytanoyl-CoA + NADP+ ,
1.3.1.38: a 2,3,4-saturated fatty acyl CoA + NADP+ = a trans-2-enoyl-CoA + NADPH + H+ ,
1.3.1.48: (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+ ,
1.3.1.70: 4,4-dimethylzymosterol + NADP+ ← 14-demethyllanosterol + NADPH + H+ ,
1.3.1.70: 4α-methyl-5α-ergosta-8,24-dien-3β-ol + NADP+ = 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + NADPH + H+ ,
1.3.1.70: 4,4-dimethyl-5α-cholesta-8-en-3-β-ol + NADP+ ← 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + NADPH + H+ ,
1.3.1.72: desmosterol + NADPH + H+ → cholesterol + NADP+ ,
1.3.1.72: lanosterol + NADPH + H+ → 24,25-dihydrolanosterol + NADP+ ,
1.3.1.72: lathosterol + NADP+ ← 5α-cholesta-7,24-dien-3β-ol + NADPH + H+ ,
1.3.1.93: a very-long-chain 2,3,4-saturated fatty acyl CoA + NADP+ = a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ ,
1.3.1.94: a ditrans,polycis-dolichol + NADP+ = a di-trans, poly-cis-polyprenol + NADPH + H+ ,
1.3.1.96: squalene + NADP+ + diphosphate = presqualene diphosphate + NADPH + H+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.3.6: a 2,3,4-saturated fatty acyl CoA + oxygen → a trans-2-enoyl-CoA + hydrogen peroxide ,
1.3.3.6: an acyl-CoA + oxygen → a trans-2-enoyl-CoA + hydrogen peroxide ,
1.3.5.1: succinate[mitochondrial lumen] + an ubiquinone[mitochondrial inner membrane] → fumarate[mitochondrial lumen] + an ubiquinol[mitochondrial inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an electron-transfer-related quinone[inner membrane] → orotate + an electron-transfer-related quinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an ubiquinone[inner membrane] → orotate + an ubiquinol[inner membrane] ,
1.3.8.4: isovaleryl-CoA + an oxidized electron-transfer flavoprotein → 3-methylcrotonyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.5: 2-methylbutanoyl-CoA + an oxidized electron-transfer flavoprotein → (E)-2-methylcrotonoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.6: glutaryl-CoA + an oxidized electron-transfer flavoprotein = crotonyl-CoA + CO2 + a reduced electron-transfer flavoprotein ,
1.3.8.7: a medium-chain 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein = a medium-chain trans-2,3-dehydroacyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.7: decanoyl-CoA + an oxidized electron-transfer flavoprotein = trans-Δ2-decenoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.8: a long-chain 2,3,4-saturated fatty acyl CoA[mitochondrial lumen] + an oxidized electron-transfer flavoprotein[mitochondrial lumen] = a long-chain trans-2,3-dehydroacyl-CoA[mitochondrial lumen] + a reduced electron-transfer flavoprotein[mitochondrial lumen] ,
1.3.8.-: isobutanoyl-CoA + FAD + H+ → methylacrylyl-CoA + FADH2 ,
1.3.8.-: a 2,3,4-saturated fatty acyl CoA[mitochondrial lumen] + an oxidized electron-transfer flavoprotein[mitochondrial lumen] + H+[mitochondrial lumen] → a trans-2-enoyl-CoA[mitochondrial lumen] + a reduced electron-transfer flavoprotein[mitochondrial lumen] ,
1.3.98.1: (S)-dihydroorotate + fumarate → orotate + succinate ,
1.3.99.6: a 3-oxo-5-β-steroid + an oxidized electron acceptor = a 3-oxo-Δ4-steroid + a reduced electron acceptor ,
1.3.99.12: 2-methylbutanoyl-CoA + an oxidized electron acceptor = (E)-2-methylcrotonoyl-CoA + a reduced electron acceptor ,
1.3.99.23: all-trans-13,14-dihydroretinol + an oxidized electron acceptor = all-trans-retinol + a reduced electron acceptor ,
1.3.99.-: pseudooxynicotine + oxygen + 2 H2O → 4-oxo-4-(3-pyridyl)-butanoate + methylamine + hydrogen peroxide ,
1.4.1.2: L-glutamate[mitochondrial lumen] + NAD+[mitochondrial lumen] + H2O[mitochondrial lumen] = 2-oxoglutarate[mitochondrial lumen] + ammonium[mitochondrial lumen] + NADH[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.4.1.3: L-glutamate[mitochondrial lumen] + NAD(P)+[mitochondrial lumen] + H2O[mitochondrial lumen] ↔ 2-oxoglutarate[mitochondrial lumen] + ammonium[mitochondrial lumen] + NAD(P)H[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.4.1.21: L-aspartate + NAD(P)+ + H2O = oxaloacetate + ammonium + NAD(P)H + H+ ,
1.4.3.2: L-arginine + oxygen + H2O → ammonium + 2-ketoarginine + hydrogen peroxide ,
1.4.3.2: a standard α amino acid + oxygen + H2O → ammonium + hydrogen peroxide + a 2-oxo carboxylate ,
1.4.3.3: a D-amino acid + oxygen + H2O → ammonium + hydrogen peroxide + a 2-oxo carboxylate ,
1.4.3.4: 2-phenylethylamine + oxygen + H2O → phenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: metanephrine + H2O + oxygen → 3-methoxy-4-hydroxyphenylglycolaldehyde + methylamine + hydrogen peroxide ,
1.4.3.4: N-acetylputrescine + H2O + oxygen → 4-acetamidobutanal + ammonium + hydrogen peroxide ,
1.4.3.4: dopamine + H2O + oxygen → 3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: a monoamine + H2O + oxygen → an aldehyde + a primary amine + hydrogen peroxide ,
1.4.3.4: 5-methoxytryptamine + H+ + H2O + oxygen → 5-methoxyindoleacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: (R)-adrenaline + H2O + oxygen → 3,4-dihydroxyphenylglycolaldehyde + methylamine + hydrogen peroxide ,
1.4.3.4: serotonin + oxygen + H2O → 5-hydroxyindole acetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: (R)-noradrenaline + H2O + oxygen → 3,4-dihydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: tryptamine + H2O + oxygen → ammonium + indole acetaldehyde + hydrogen peroxide ,
1.4.3.4: normetanephrine + H2O + oxygen → 3-methoxy-4-hydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.5: pyridoxamine 5'-phosphate + oxygen + H2O → ammonium + hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.13: a [protein]-L-lysine + oxygen + H2O → a protein L-allysine + ammonium + hydrogen peroxide ,
1.4.3.21: cadaverine + H2O + oxygen → 5-aminopentanal + ammonium + hydrogen peroxide ,
1.4.3.21: aminoacetone + H2O + oxygen → methylglyoxal + ammonium + hydrogen peroxide ,
1.4.3.21: 2-phenylethylamine + oxygen + H2O → phenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.21: an aliphatic amine + H2O + oxygen → an aldehyde + ammonium + hydrogen peroxide ,
1.4.3.21: a primary amine + H2O + oxygen → an aldehyde + ammonium + hydrogen peroxide ,
1.4.3.22: a diamine + H2O + oxygen → a monoamine + ammonium + hydrogen peroxide ,
1.4.3.22: histamine + H2O + oxygen → imidazole acetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.-: L-tryptophan + oxygen → 2-imino-3-(indol-3-yl)propanoate + hydrogen peroxide + H+ ,
1.5.1.2: trans-4-hydroxy-L-proline + NAD(P)+ ← (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: a tetrahydrofolate + NADP+ ← a 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: a 5,10-methylene-tetrahydrofolate + NADP+ ↔ a 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.6: an N10-formyl-tetrahydrofolate + NADP+ + H2O = a tetrahydrofolate + CO2 + NADPH + H+ ,
1.5.1.8: L-saccharopine + NADP+ + H2O ← 2-oxoglutarate + L-lysine + NADPH + H+ ,
1.5.1.9: L-saccharopine + NAD+ + H2O → L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+ ,
1.5.1.15: a 5,10-methylene-tetrahydrofolate + NAD+ → a 5,10-methenyltetrahydrofolate + NADH ,
1.5.1.20: an N5-methyl-tetrahydrofolate + NAD+ ← a 5,10-methylene-tetrahydrofolate + NADH + H+ ,
1.5.1.21: L-pipecolate + NADP+ ← (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NADPH + 2 H+ ,
1.5.1.21: L-pipecolate + NAD(P)+ ← Δ1-piperideine-2-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.25: thiomorpholine-3-carboxylate + NAD(P)+ = 3,4-dehydrothiomorpholine-3-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.27: (R)-reticuline + NADP+ ← 1,2-dehydroreticulinium + NADPH + H+ ,
1.5.1.30: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+ ,
1.5.1.34: a 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H+ ,
1.5.1.38: NADP+ + FMNH2 = NADPH + FMN + 2 H+ ,
1.5.1.39: FMNH2 + NAD(P)+ = FMN + NAD(P)H + 2 H+ ,
1.5.1.-: L-erythro-5,6,7,8-tetrahydrobiopterin + NAD+ ← L-erythro-7,8-dihydrobiopterin + NADH + H+ ,
1.5.1.-: tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ ,
1.5.3.1: sarcosine + oxygen + H2O → hydrogen peroxide + formaldehyde + glycine ,
1.5.3.7: L-pipecolate + oxygen → (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + hydrogen peroxide + H+ ,
1.5.3.13/1.5.3.17: N1-acetylspermidine + oxygen + H2O → putrescine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.13: N1,N12-diacetylspermine + oxygen + H2O → N1-acetylspermidine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.13: N1-acetylspermine + oxygen + H2O → spermidine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.14: spermine + oxygen + H2O → 1-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide ,
1.5.3.16: norspermine + oxygen + H2O → norspermidine + 3-aminopropanal + hydrogen peroxide ,
1.5.3.16: N1-acetylspermine + oxygen + H2O → hydrogen peroxide + 3-aminopropanal + N1-acetylspermidine ,
1.5.3.17: spermine + H2O + oxygen → 3-aminopropanal + spermidine + hydrogen peroxide ,
1.5.5.2: L-proline[in] + an ubiquinone[in] → (S)-1-pyrroline-5-carboxylate[in] + an ubiquinol[in] + H+[in] ,
1.5.5.2: L-proline[in] + an electron-transfer-related quinone → (S)-1-pyrroline-5-carboxylate[in] + an electron-transfer-related quinol + H+[in] ,
1.5.5.2: L-proline[in] + an ubiquinone[in] → (S)-1-pyrroline-5-carboxylate[in] + an ubiquinol[in] + H+[in] ,
1.5.5.-: trans-4-hydroxy-L-proline[in] + an electron-transfer-related quinone → (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate[in] + an electron-transfer-related quinol + H+[in] ,
1.5.8.3: sarcosine + an oxidized electron-transfer flavoprotein + H2O + H+ = glycine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.8.4: dimethylglycine + an oxidized electron-transfer flavoprotein + H2O + H+ = sarcosine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.8.-: dimethylglycine + an oxidized electron-transfer flavoprotein + a tetrahydrofolate → sarcosine + a 5,10-methenyltetrahydrofolate + a reduced electron-transfer flavoprotein ,
1.5.8.-: (S)-nicotine + an oxidized flavoprotein → nicotine-Δ1'5'-iminium ion + a reduced flavoprotein ,
1.5.8.-: sarcosine + an oxidized electron-transfer flavoprotein + a tetrahydrofolate → glycine + a 5,10-methenyltetrahydrofolate + a reduced electron-transfer flavoprotein ,
1.6.1.2/1.6.1.3: NADPH + NAD+ = NADH + NADP+ ,
1.6.1.2: NADH + NADP+ + H+[out] → NADPH + NAD+ + H+[in] ,
1.6.3.1: NAD(P)H + H+ + oxygen → hydrogen peroxide + NAD(P)+ ,
1.6.5.2: a quinone + NAD(P)H + H+ → a quinol + NAD(P)+ ,
1.6.5.2: a plastoquinone + NAD(P)H + H+ ↔ a plastoquinol + NAD(P)+ ,
1.6.5.3: NADH[mitochondrial lumen] + an ubiquinone[mitochondrial inner membrane] + 5 H+[mitochondrial lumen] ↔ NAD+[mitochondrial lumen] + an ubiquinol[mitochondrial inner membrane] + 4 H+[mitochondrial intermembrane space] ,
1.6.5.4: 2 monodehydroascorbate radical + NADH → 2 L-ascorbate + NAD+ + H+ ,
1.6.5.5: a quinone + NADPH = a semiquinone + NADP+ ,
1.6.5.9: NADH + an ubiquinone[inner membrane] + H+ → NAD+ + an ubiquinol[inner membrane] ,
1.6.5.10: NADPH + an electron-transfer-related quinone + H+ = NADP+ + an electron-transfer-related quinol ,
1.6.5.-: 2 monodehydroascorbate radical + NADPH + H+ → 2 L-ascorbate + NADP+ + 2 H+ ,
1.6.99.3: NADH + an oxidized electron acceptor + H+ = NAD+ + a reduced electron acceptor ,
1.7.1.7: ammonium + IMP + NADP+ = GMP + NADPH + 2 H+ ,
1.8.1.3: hypotaurine + NAD+ + H2O → taurine + NADH + H+ ,
1.8.1.7: 2 glutathione + NADP+ ← glutathione disulfide + NADPH + H+ ,
1.8.1.8: a protein dithiol + NAD(P)+ = a protein disulfide + NAD(P)H + H+ ,
1.8.3.1: sulfite + oxygen + H2O → hydrogen peroxide + sulfate ,
1.8.3.2: 2 R'C(R)SH + oxygen → R'C(R)S-S(R)CR' + hydrogen peroxide ,
1.8.3.5: S-prenyl-L-cysteine + H2O + oxygen → 3-methyl-2-butenal + hydrogen peroxide + L-cysteine ,
1.8.3.6: S-(2E,6E)-farnesyl-L-cysteine + oxygen + H2O → (2E,6E)-farnesal + L-cysteine + hydrogen peroxide ,
1.8.4.2: 2 glutathione + a protein disulfide = glutathione disulfide + a protein dithiol ,
1.8.5.1: L-dehydro-ascorbate + 2 glutathione → L-ascorbate + glutathione disulfide + H+ ,
1.8.5.4: hydrogen sulfide + an electron-transfer-related quinone = intracellular S0 + an electron-transfer-related quinol ,
1.8.98.2: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + a protein dithiol = peroxiredoxin-(S-hydroxycysteine) + ADP + a protein disulfide + phosphate + H+ ,
1.9.3.1/1.10.2.2: 2 an ubiquinol[mitochondrial inner membrane] + oxygen[mitochondrial lumen] + 12 H+[mitochondrial lumen] → 2 an ubiquinone[mitochondrial inner membrane] + 2 H2O[mitochondrial lumen] + 12 H+[mitochondrial intermembrane space] ,
1.10.3.1: 2 cis-caffeate + oxygen → 2 3-(2-propenoic acid)-o-benzoquinone + 2 H2O ,
1.10.3.1: 2 catechol + oxygen → 2 1,2-benzoquinone + 2 H2O ,
1.10.3.-: L-dopa + 0.5 oxygen → dopaquinone + H2O ,
1.10.99.2: 1-(β-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H+ = a quinol + 1-(β-D ribofuranosyl)nicotinamide ,
1.11.1.6: ethanol + hydrogen peroxide → acetaldehyde + 2 H2O ,
1.11.1.7: a phenolic donor + hydrogen peroxide = 2 a phenoxyl radical of a phenolic donor + 2 H2O ,
1.11.1.7: 2 betanidin + hydrogen peroxide = betanidin + betanidin quinone + 2 H2O ,
1.11.1.8: [thyroglobulin]-3-iodotyrosine + [thyroglobulin]-3,5-diiodotyrosine + hydrogen peroxide → [thyroglobulin]-triiodothyronine + [thyroglobulin]-aminoacrylate + 2 H2O ,
1.11.1.8: [thyroglobulin]-3-iodotyrosine + iodide + hydrogen peroxide + H+ → [thyroglobulin]-3,5-diiodotyrosine + 2 H2O ,
1.11.1.8: hydrogen peroxide + 2 iodide + 2 H+ = I2 + 2 H2O ,
1.11.1.8: [thyroglobulin]-L-tyrosine + hydrogen peroxide + iodide + H+ → [thyroglobulin]-3-iodotyrosine + 2 H2O ,
1.11.1.8: 2 [thyroglobulin]-3,5-diiodotyrosine + hydrogen peroxide → [thyroglobulin]-L-thyroxine + [thyroglobulin]-aminoacrylate + 2 H2O ,
1.11.1.9: hydrogen peroxide + 2 glutathione → glutathione disulfide + 2 H2O ,
1.11.1.11: 2 L-ascorbate + hydrogen peroxide + H+ → L-ascorbate + L-dehydro-ascorbate + 2 H2O ,
1.11.1.12: a lipid hydroperoxide + 2 glutathione + H+ → a lipid + glutathione disulfide + 2 H2O ,
1.11.1.15: 2 protein cysteines + an organic hydroperoxide = a protein disulfide + an alcohol + H2O ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.11.2.2: chloride + hydrogen peroxide + H+ = hypochlorous acid + H2O ,
1.13.11.5: homogentisate + oxygen → 4-maleyl-acetoacetate + H+ ,
1.13.11.6: 3-hydroxyanthranilate + oxygen → aminocarboxymuconate semialdehyde + H+ ,
1.13.11.11/1.13.11.52: L-tryptophan + oxygen → N-formylkynurenine ,
1.13.11.19: cysteamine + oxygen → hypotaurine + H+ ,
1.13.11.20: L-cysteine + oxygen → 3-sulfinoalanine + H+ ,
1.13.11.27: 2-oxo-3-phenylpropanoate + oxygen → 2-hydroxyphenylacetate + CO2 ,
1.13.11.27: 4-hydroxyphenylpyruvate + oxygen → CO2 + homogentisate ,
1.13.11.31: arachidonate + oxygen → (12S)-HPETE ,
1.13.11.33: arachidonate + oxygen → (15S)-HPETE ,
1.13.11.34: arachidonate + oxygen → leukotriene A4 + H2O ,
1.13.11.52: D-tryptophan + oxygen → N-formyl-D-kynurenine ,
1.13.11.54: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 2-oxo-4-methylthiobutanoate + formate + H+ ,
1.13.11.63: all-trans-β-carotene + oxygen → 2 all-trans-retinal ,
1.13.11.71: all-trans-β-carotene + oxygen → all-trans-10'-apo-β-carotenal + β-ionone ,
1.13.11.-: all-trans-10'-apo-β-carotenal + oxygen → β-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaene-1,12-dial ,
1.13.11.-: 4-methyl-2-oxopentanoate + oxygen → 3-hydroxyisovalerate + CO2 ,
1.13.11.-: leukotriene A4 + a reduced electron acceptor + oxygen → lipoxin B4 + an oxidized electron acceptor ,
1.13.11.-: leukotriene A4 + a reduced electron acceptor + oxygen → lipoxin A4 + an oxidized electron acceptor ,
1.13.11.-: all-trans-β-carotene + 2 oxygen → 2 β-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaene-1,12-dial ,
1.13.99.1: myo-inositol + oxygen → D-glucopyranuronate + H+ + H2O ,
1.14.11.1: 2-oxoglutarate + γ-butyrobetaine + oxygen → L-carnitine + CO2 + succinate ,
1.14.11.2: a [procollagen]-L-proline + 2-oxoglutarate + oxygen → a [procollagen] trans 4-hyroxy-L-proline + CO2 + succinate ,
1.14.11.4: a [procollagen]-L-lysine + 2-oxoglutarate + oxygen → a [procollagen]-5-hydroxy-L-lysine + CO2 + succinate ,
1.14.11.7: a [procollagen]-L-proline + 2-oxoglutarate + oxygen → a [procollagen]-3-hydroxy-L-proline + CO2 + succinate ,
1.14.11.8: 2-oxoglutarate + N6,N6,N6-trimethyl-L-lysine + oxygen → CO2 + succinate + 3-hydroxy-N6,N6,N6-trimethyl-L-lysine ,
1.14.11.16: a [protein]-L-aspartate + 2-oxoglutarate + oxygen → CO2 + succinate + a [protein]-3-hydroxy-L-aspartate ,
1.14.11.18: 2-oxoglutarate + phytanoyl-CoA + oxygen → CO2 + succinate + 2-hydroxyphytanoyl-CoA ,
1.14.11.31: thebaine + 2-oxoglutarate + oxygen → neopinone + formaldehyde + succinate + CO2 ,
1.14.11.31: oripavine + 2-oxoglutarate + oxygen → morphinone + formaldehyde + succinate + CO2 ,
1.14.11.32: thebaine + 2-oxoglutarate + oxygen → oripavine + formaldehyde + succinate + CO2 ,
1.14.11.32: codeine + 2-oxoglutarate + oxygen → morphine + formaldehyde + succinate + CO2 ,
1.14.11.33: N1-methyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + formaldehyde + succinate ,
1.14.11.33: a methylated nucleobase within DNA + 2-oxoglutarate + oxygen → a nucleobase within DNA + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: 1-ethyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + acetaldehyde + succinate ,
1.14.11.33: N3-methylcytosine + 2-oxoglutarate + oxygen → cytosine + CO2 + formaldehyde + succinate + H+ ,
1.14.11.42: 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + 2-oxoglutarate + oxygen → 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe + succinate + CO2 ,
1.14.11.-: a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + 2-oxoglutarate + oxygen → a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA + succinate + CO2 ,
1.14.11.-: a [protein] N6-methyl-L-lysine + 2-oxoglutarate + oxygen + H+ → a [protein]-L-lysine + succinate + formaldehyde + CO2 ,
1.14.13.8: N,N-dimethylaniline + NADPH + oxygen + H+N,N-dimethylaniline-N-oxide + NADP+ + H2O ,
1.14.13.8: (S)-nicotine + NADPH + oxygen → nicotine-1'-N-oxide + NADP+ + H2O ,
1.14.13.9: L-kynurenine + NADPH + oxygen + H+ → 3-hydroxy-L-kynurenine + NADP+ + H2O ,
1.14.13.13: calcidiol + NADPH + H+ + oxygen → calcitriol + NADP+ + H2O ,
1.14.13.15: 5β-cholestane-3α,7α,12α-triol + 3 NADPH + 2 H+ + 3 oxygen → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + 3 NADP+ + 4 H2O ,
1.14.13.15: 5β-cholestane-3α,7α-diol + 3 NADPH + 2 H+ + 3 oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + 3 NADP+ + 4 H2O ,
1.14.13.17: cholesterol + NADPH + H+ + oxygen → 7α-hydroxycholesterol + NADP+ + H2O ,
1.14.13.30: leukotriene B4 + NADPH + oxygen + H+ → 20-hydroxy-leukotriene B4 + NADP+ + H2O ,
1.14.13.30: α-tocopherol + NADPH + oxygen + H+ → 13'-hydroxy-α-tocopherol + NADP+ + H2O ,
1.14.13.32: albendazole + NADPH + H+ + oxygen → albendazole s-oxide + NADP+ + H2O ,
1.14.13.39: 2 L-arginine + 3 NADPH + H+ + 4 oxygen → 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O ,
1.14.13.48: (4S)-limonene + NADPH + oxygen + H+ → (-)-trans-carveol + NADP+ + H2O ,
1.14.13.49: (4S)-limonene + NADPH + oxygen + H+ → (4S)-perillyl alcohol + NADP+ + H2O ,
1.14.13.67: quinine + NADPH + H+ + oxygen → 3-hydroxyquinine + NADP+ + H2O ,
1.14.13.70: obtusifoliol + 3 NADPH + 3 oxygen + 2 H+ → formate + 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + 3 NADP+ + 4 H2O ,
1.14.13.70: 4α,14α-dimethyl-5α-cholesta-8,24-dien-3β-ol + 3 NADPH + 3 oxygen + 2 H+ → 4α-methyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 NADP+ + 4 H2O ,
1.14.13.70: 24,25-dihydrolanosterol + 3 NADPH + 3 oxygen + 2 H+ → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate + 3 NADP+ + 4 H2O ,
1.14.13.70: lanosterol + 3 NADPH + 3 oxygen + 2 H+ → 14-demethyllanosterol + formate + 3 NADP+ + 4 H2O ,
1.14.13.72: 4α-methyl-zymosterol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethylzymosterol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethyl-5α-cholesta-8-en-3-β-ol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethyl-5α-cholest-7-en-3β-ol + 3 NAD(P)H + 3 oxygen + 2 H+ → 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4α-methyl-cholesta-8-enol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-5α-cholesta-8-en-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.80: (4R)-limonene + NADPH + H+ + oxygen → (+)-trans-carveol + NADP+ + H2O ,
1.14.13.95: 7α-hydroxycholest-4-en-3-one + NADPH + H+ + oxygen → 7α,12α-dihydroxycholest-4-en-3-one + NADP+ + H2O ,
1.14.13.97: lithocholate + NADPH + H+ + oxygen → hyodeoxycholate + NADP+ + H2O ,
1.14.13.97: taurochenodeoxycholate + NADPH + H+ + oxygen → taurohyocholate + NADP+ + H2O ,
1.14.13.98: cholesterol + NADPH + H+ + oxygen → (24S)-24-hydroxycholesterol + NADP+ + H2O ,
1.14.13.99: (24R)-cholest-5-ene-3β,24-diol + NADPH + H+ + oxygen → (24R)-cholest-5-ene-3β,7α,24-triol + NADP+ + H2O ,
1.14.13.100: cholest-5-ene-3β,25-diol + NADPH + H+ + oxygen → cholest-5-ene-3β,7α,25-triol + NADP+ + H2O ,
1.14.13.100: (25R)-cholest-5-ene-3β,26-diol + NADPH + H+ + oxygen → (25R)-cholest-5-ene-3β,7α,26-triol + NADP+ + H2O ,
1.14.13.126: calcitriol + NADPH + H+ + oxygen → calcitetrol + NADP+ + H2O ,
1.14.13.126: calcidiol + NADPH + H+ + oxygen → secalciferol + NADP+ + H2O ,
1.14.13.132: squalene + NADPH + oxygen + H+ → (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O ,
1.14.13.148: trimethylamine + NADPH + oxygen → trimethylamine N-oxide + NADP+ + H2O ,
1.14.13.159: vitamin D3 + NADPH + H+ + oxygen → calcidiol + NADP+ + H2O ,
1.14.13.-: oleate + NADPH + oxygen + H+ → 18-hydroxyoleate + NADP+ + H2O ,
1.14.13.-: 7-dehydrocholesterol + NADPH + H+ + oxygen → 7-ketocholesterol + NADP+ + H2O ,
1.14.13.-: 2-methoxy-6-(all-trans-decaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
1.14.13.-: indole + NADH + oxygen + H+ → indoxyl + NAD+ + H2O ,
1.14.13.-: 17-α-hydroxyprogesterone + NADPH + H+ + oxygen → 11-desoxycortisol + NADP+ + H2O ,
1.14.13.-: (4S)-limonene + NADPH + oxygen + H+ → (-)-cis-carveol + NADP+ + H2O ,
1.14.13.-: 3-decaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + NADP+ + H2O ,
1.14.13.-: progesterone + NADPH + H+ + oxygen → 11-deoxycorticosterone + NADP+ + H2O ,
1.14.14.1: melatonin + a reduced flavoprotein + oxygen → N-acetyl-serotonin + an oxidized flavoprotein + formaldehyde + H2O ,
1.14.14.1: 4-hydroxybenzaldehyde + a reduced flavoprotein + oxygen → protocatechualdehyde + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → trans-3'-hydroxycotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: (S)-nicotine + a reduced flavoprotein + oxygen → 2'-hydroxynicotine + an oxidized flavoprotein + H2O ,
1.14.14.1: melatonin + a reduced flavoprotein + oxygen → 6-hydroxymelatonin + an oxidized flavoprotein + H2O ,
1.14.14.1: bupropion + a reduced flavoprotein + oxygen → hydroxybupropion + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → 5'-hydroxycotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → N'-hydroxymethyl-norcotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: acetone + a reduced flavoprotein + oxygen → acetol + an oxidized flavoprotein + H2O ,
1.14.14.-: N'-hydroxymethyl-norcotinine + a reduced flavoprotein + oxygen → norcotinine + an oxidized flavoprotein + H2O ,
1.14.15.4: 11-desoxycortisol + 2 a reduced adrenodoxin + oxygen + 2 H+ → cortisol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.4: 11-deoxycorticosterone + 2 a reduced adrenodoxin + oxygen + 2 H+ → corticosterone + 2 an oxidized adrenodoxin + H2O ,
1.14.15.5: 18-hydroxycorticosterone + 2 a reduced adrenodoxin + 2 H+ + oxygen → aldosterone + 2 an oxidized adrenodoxin + 2 H2O ,
1.14.15.5: corticosterone + 2 a reduced adrenodoxin + oxygen + 2 H+ → 18-hydroxycorticosterone + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: (22R)-hydroxycholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → (20R,22R)-dihydroxycholesterol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: cholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → (22R)-hydroxycholesterol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: (20R,22R)-dihydroxycholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → pregnenolone + 4-methylpentanal + 2 an oxidized adrenodoxin + 2 H2O ,
1.14.16.1: L-phenylalanine + L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen = L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.14.16.1: tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.14.16.2: tetrahydrobiopterin + L-tyrosine + oxygen → 4α-hydroxy-tetrahydrobiopterin + L-dopa ,
1.14.16.4: tetrahydrobiopterin + L-tryptophan + oxygen → 5-hydroxy-L-tryptophan + 4α-hydroxy-tetrahydrobiopterin ,
1.14.17.1: dopamine + L-ascorbate + H+ + oxygen → L-dehydro-ascorbate + (R)-noradrenaline + H2O ,
1.14.17.3: a C-terminal [protein]-glycine + L-ascorbate + oxygen → a C-terminal [protein]-hydroxyglycine + L-dehydro-ascorbate + H2O ,
1.14.18.1: L-tyrosine + oxygen → dopaquinone + H2O ,
1.14.19.3: linoleoyl-CoA + a reduced electron acceptor + oxygen → γ-linolenoyl-CoA + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: eicosatetraenoyl-CoA + a reduced electron acceptor + oxygen → eicosapentaenoyl-CoA + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: α-linolenoyl-CoA + a reduced electron acceptor + oxygen → stearidonoyl-CoA + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: linoleate + a reduced electron acceptor + oxygen → γ-linolenate + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: oleate + a reduced electron acceptor + oxygen → linoleate + an oxidized electron acceptor + 2 H2O ,
1.14.21.4: (R)-reticuline + NADPH + H+ + oxygen → salutaridine + NADP+ + 2 H2O ,
1.14.21.6: 5α-cholesta-7,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 7-dehydrodesmosterol + NAD(P)+ + 2 H2O ,
1.14.21.6: lathosterol + NAD(P)H + oxygen + H+ → 7-dehydrocholesterol + NAD(P)+ + 2 H2O ,
1.14.99.1: arachidonate + a reduced electron acceptor + 2 oxygen → prostaglandin-H2 + an oxidized electron acceptor + H2O ,
1.14.99.3: ferroheme b + 3 a reduced electron acceptor + 3 oxygen + 2 H+ → carbon monoxide + Fe2+ + biliverdin-IX-α + 3 an oxidized electron acceptor + 3 H2O ,
1.14.99.9: pregnenolone + NADPH + H+ + oxygen → 17-α-hydroxypregnenolone + NADP+ + H2O ,
1.14.99.9: a C21-steroid + a reduced electron acceptor + oxygen → a 17α-hydroxy-C21-steroid + an oxidized electron acceptor + H2O ,
1.14.99.9: progesterone + NADPH + oxygen + H+ → 17-α-hydroxyprogesterone + NADP+ + H2O ,
1.14.99.10: a C21-steroid + a reduced [NADPH-hemoprotein reductase] + oxygen → a 21-hydroxy-C21-steroid + an oxidized [NADPH-hemoprotein reductase] + H2O ,
1.14.99.36: all-trans-β-carotene + oxygen → 2 all-trans-retinal ,
1.14.99.38: cholesterol + a reduced electron acceptor + oxygen → cholest-5-ene-3β,25-diol + an oxidized electron acceptor + H2O ,
1.14.-.-: 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen → 3-demethylubiquinol-10 + an oxidized electron acceptor + H2O ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.16.1.7: 2 an Fe(II)-siderophore + NAD+ + H+ ← 2 an Fe(III)-siderophore + NADH ,
1.16.3.1: 4 Fe2+ + 4 H+ + oxygen → 4 Fe3+ + 2 H2O ,
1.16.5.1: L-ascorbate[in] + Fe3+[out] ↔ monodehydroascorbate radical[in] + Fe2+[out] ,
1.16.5.1: L-ascorbate[in] + Fe3+[out] → monodehydroascorbate radical[in] + Fe2+[out] ,
1.17.1.4: hypoxanthine + NAD+ + H2O → xanthine + NADH + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.1.-: an all-trans retinol-[cellular-retinol-binding-protein] + NAD+ + H2O → all-trans-retinoate + NADH + H+ ,
1.17.3.2: an organic molecule + H2O + 2 oxygen → an alcohol + 2 superoxide + 2 H+ ,
1.17.3.2: xanthine + oxygen + H2O → hydrogen peroxide + urate ,
1.17.4.-: oxidized dithiothreitol + phylloquinone + H2O = dithiothreitol + vitamin K 2,3-epoxide ,
1.17.7.2: 71-hydroxychlorophyll a + 2 a reduced ferredoxin + 2 H+ = chlorophyll a + 2 an oxidized ferredoxin + H2O ,
1.17.99.3: (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an oxidized electron acceptor + H2O = (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + a reduced electron acceptor ,
1.17.99.-: (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an oxidized electron acceptor → (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + a reduced electron acceptor ,
1.20.4.2: 2 glutathione + methylarsonate → glutathione disulfide + methylarsonite ,
1.21.1.-: L-tyrosine + 2 iodide + 2 NADP+ ← 3,5-diiodo-L-tyrosine + 2 NADPH + H+ ,
1.97.1.10: 3',5'-diiodothyronine + a reduced electron acceptor → 3'-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.97.1.10: 3,5,3'-triiodo-L-thyronine + iodide + an oxidized electron acceptor + H+ ← L-thyroxine + a reduced electron acceptor ,
1.97.1.10: 3,3',5'-triiodo-L-thyronine + a reduced electron acceptor → 3,3'-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.97.1.11: 3,3',5'-triiodo-L-thyronine + iodide + an oxidized electron acceptor + H+ ← L-thyroxine + a reduced electron acceptor ,
1.97.1.11: 3,5,3'-triiodo-L-thyronine + a reduced electron acceptor → 3,3'-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.97.1.11: 3,5-diiodothyronine + a reduced electron acceptor → 3-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.-.-.-: an even numbered straight chain 2,3,4-saturated fatty acid + NAD(P)H + H+ + oxygen → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + NAD(P)+ + H2O ,
2.1.1.1: nicotinamide + S-adenosyl-L-methionine → 1-methylnicotinamide + S-adenosyl-L-homocysteine ,
2.1.1.2: guanidinoacetate + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + creatine + H+ ,
2.1.1.4: N-acetyl-serotonin + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + melatonin + H+ ,
2.1.1.5: L-homocysteine + glycine betaine → L-methionine + dimethylglycine ,
2.1.1.6: 3,4-dihydroxymandelate + S-adenosyl-L-methionine → vanillyl mandelate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: (R)-noradrenaline + S-adenosyl-L-methionine → normetanephrine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: a catechol + S-adenosyl-L-methionine → a guaiacol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: (R)-adrenaline + S-adenosyl-L-methionine → metanephrine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: L-dopa + S-adenosyl-L-methionine → 3-O-methyldopa + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: S-adenosyl-L-methionine + dopamine → S-adenosyl-L-homocysteine + 3-methoxytyramine + H+ ,
2.1.1.6: 3,4-dihydroxyphenylglycol + S-adenosyl-L-methionine → 3-methoxy-4-hydroxyphenylglycol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: 3,4-dihydroxyphenylacetate + S-adenosyl-L-methionine → homovanillate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: orcinol + S-adenosyl-L-methionine → 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine + H+ ,
2.1.1.8: histamine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + Nτ-methylhistamine + H+ ,
2.1.1.10: S-methyl-L-methionine + L-homocysteine → 2 L-methionine + H+ ,
2.1.1.13: L-homocysteine + an N5-methyl-tetrahydrofolate → L-methionine + a tetrahydrofolate ,
2.1.1.17: an L-1-phosphatidyl-ethanolamine + S-adenosyl-L-methionine → a phosphatidyl-N-methylethanolamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.19: a tetrahydrofolate + trimethyl sulfonium ← dimethyl sulfide + an N5-methyl-tetrahydrofolate + H+ ,
2.1.1.20: S-adenosyl-L-methionine + glycine → S-adenosyl-L-homocysteine + sarcosine + H+ ,
2.1.1.28: phenylethanolamine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + N-methylphenylethanolamine + H+ ,
2.1.1.28: S-adenosyl-L-methionine + (R)-noradrenaline → S-adenosyl-L-homocysteine + (R)-adrenaline + H+ ,
2.1.1.43: a [histone]-L-lysine + S-adenosyl-L-methionine → a [histone] N6-methyl-L-lysine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.45: a 5,10-methylene-tetrahydrofolate + dUMP → dTMP + a 7,8-dihydrofolate ,
2.1.1.49: (S)-nicotine + S-adenosyl-L-methionine → nicotine isomethonium ion + S-adenosyl-L-homocysteine ,
2.1.1.49: an amine + S-adenosyl-L-methionine → a methylated amine + S-adenosyl-L-homocysteine ,
2.1.1.62: m7G(5')pppAm + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + m7G(5')pppm6Am + H+ ,
2.1.1.64: S-adenosyl-L-methionine + 3-demethylubiquinol-10 → S-adenosyl-L-homocysteine + ubiquinol-10 + H+ ,
2.1.1.67: a thiopurine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + a thiopurine S-methylether + H+ ,
2.1.1.77: S-adenosyl-L-methionine + a [protein]-L-β-isoaspartate → S-adenosyl-L-homocysteine + a protein L-β-isoaspartate α-methyl ester ,
2.1.1.100: a [protein] c-terminal S-farnesyl-L-cysteine + S-adenosyl-L-methionine → a protein c-terminal s-farnesyl-l-cysteine methyl ester + S-adenosyl-L-homocysteine ,
2.1.1.114: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine → 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.125: S-adenosyl-L-methionine + [histone]-L-arginine → S-adenosyl-L-homocysteine + [histone]-Nω-methyl-arginine + 2 H+ ,
2.1.1.126: S-adenosyl-L-methionine + [myelin basic protein]-L-arginine → S-adenosyl-L-homocysteine + [myelin basic protein]-Nω-methyl-arginine + H+ ,
2.1.1.137: arsenite + S-adenosyl-L-methionine → methylarsonate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.137: S-adenosyl-L-methionine + methylarsonite → S-adenosyl-L-homocysteine + cacodylate + 2 H+ ,
2.1.1.201: 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine → 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-decaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: a 3-(all-trans-polyrenyl)benzene-1,2-diol + S-adenosyl-L-methionine → a 2-methoxy-6-(all-trans-polyprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-nonaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-nonaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-heptaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-heptaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.233: S-adenosyl-L-methionine + a [phosphatase 2A protein] C-terminal L-leucine → S-adenosyl-L-homocysteine + a [phosphatase 2A protein] C-terminal L-leucine methyl ester ,
2.1.1.244: 3 S-adenosyl-L-methionine + an N-terminal-(A/S)PK-[protein] → 3 S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein] + 3 H+ ,
2.1.1.244: 2 S-adenosyl-L-methionine + an N-terminal-PPK-[protein] → 2 S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-PPK-[protein] + 2 H+ ,
2.1.1.282: S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPheS-adenosyl-L-homocysteine + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + H+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl acceptor → S-adenosyl-L-homocysteine + a methylated methyl acceptor + H+ ,
2.1.2.1: L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H2O ,
2.1.2.2: an N10-formyl-tetrahydrofolate + N1-(5-phospho-β-D-ribosyl)glycinamide → a tetrahydrofolate + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + H+ ,
2.1.2.3: an N10-formyl-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide → a tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
2.1.2.5: a 5-formiminotetrahydrofolate + L-glutamate ← N-formimino-L-glutamate + a tetrahydrofolate ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate → L-citrulline + phosphate + H+ ,
2.1.4.1: glycine + L-arginine → guanidinoacetate + L-ornithine ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ← D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate → β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate → β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.3.1.1: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.4: D-glucosamine 6-phosphate + acetyl-CoA → N-acetyl-D-glucosamine 6-phosphate + coenzyme A + H+ ,
2.3.1.5: an arylamine + acetyl-CoA = an N-acetylarylamine + coenzyme A ,
2.3.1.6: choline + acetyl-CoA = acetylcholine + coenzyme A ,
2.3.1.7: L-carnitine + acetyl-CoA ← O-acetylcarnitine + coenzyme A ,
2.3.1.9: acetyl-CoA + propanoyl-CoA = β-ketovaleryl-CoA + coenzyme A ,
2.3.1.9: 2-methylacetoacetyl-CoA + coenzyme A ↔ propanoyl-CoA + acetyl-CoA ,
2.3.1.9: 2 acetyl-CoA ↔ acetoacetyl-CoA + coenzyme A ,
2.3.1.12: acetyl-CoA + dihydrolipoamide = S-acetyldihydrolipoamide + coenzyme A ,
2.3.1.13: glycine + an acyl-CoA = an N-acylglycine + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.16: acetyl-CoA + octanoyl-CoA = 3-oxodecanoyl-CoA + coenzyme A ,
2.3.1.16: jasmonoyl-CoA + acetyl-CoA = OPC4-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: OPC4-CoA + acetyl-CoA = OPC6-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: acetyl-CoA + butanoyl-CoA = 3-oxohexanoyl-CoA + coenzyme A ,
2.3.1.16: 4-hydroxybenzoyl-CoA + acetyl-CoA = 4-hydroxybenzoyl-acetyl-CoA + coenzyme A ,
2.3.1.16: a 2,3,4-saturated fatty acyl CoA + acetyl-CoA ↔ a 3-oxoacyl-CoA + coenzyme A ,
2.3.1.16: OPC6-CoA + acetyl-CoA = OPC8-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + acetyl-CoA = 3,22-dioxochol-4-en-24-oyl-CoA + coenzyme A ,
2.3.1.20: a 1,2-diacyl-sn-glycerol + an acyl-CoA → a triacyl-sn-glycerol + coenzyme A ,
2.3.1.21: L-carnitine + palmitoyl-CoA = L-palmitoylcarnitine + coenzyme A ,
2.3.1.21: a long-chain acyl-CoA + L-carnitine ↔ an O-acyl-L-carnitine + coenzyme A ,
2.3.1.22: a 2-monoglyceride + an acyl-CoA = a 1,2-diacyl-sn-glycerol + coenzyme A ,
2.3.1.23: an acyl-CoA + a 2-lyso-phosphatidylcholine ↔ a phosphatidylcholine + coenzyme A ,
2.3.1.24: phytosphingosine + a very long chain fatty acyl-CoA = a phytoceramide + coenzyme A + H+ ,
2.3.1.24: an acyl-CoA + a sphingoid base = a ceramide + coenzyme A + H+ ,
2.3.1.26: cholesterol + an acyl-CoA = a cholesterol ester + coenzyme A ,
2.3.1.29: glycine + acetyl-CoA = 2-amino-3-oxobutanoate + coenzyme A + H+ ,
2.3.1.37: glycine + succinyl-CoA + H+ → CO2 + 5-aminolevulinate + coenzyme A ,
2.3.1.42: a long-chain acyl-CoA + dihydroxyacetone phosphate = an acylglycerone phosphate + coenzyme A ,
2.3.1.43: a sterol + a phosphatidylcholine = a 2-lyso-phosphatidylcholine + a steryl-ester ,
2.3.1.50: L-serine + palmitoyl-CoA + H+ → CO2 + 3-dehydrosphinganine + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.57: acetyl-CoA + spermidine → N1-acetylspermidine + coenzyme A + H+ ,
2.3.1.57: an aliphatic α,ω-diamine + acetyl-CoA = an aliphatic N-acetyl-diamine + coenzyme A + H+ ,
2.3.1.57: putrescine + acetyl-CoA → N-acetylputrescine + coenzyme A + H+ ,
2.3.1.57: spermine + acetyl-CoA → N1-acetylspermine + coenzyme A + H+ ,
2.3.1.65: glycine + choloyl-CoA → glycocholate + coenzyme A + H+ ,
2.3.1.65: choloyl-CoA + taurine → taurocholate + coenzyme A + H+ ,
2.3.1.65: chenodeoxycholoyl-CoA + taurine → taurochenodeoxycholate + coenzyme A + H+ ,
2.3.1.65: chenodeoxycholoyl-CoA + glycine → glycochenodeoxycholate + coenzyme A + H+ ,
2.3.1.67: acetyl-CoA + a 1-alkyl-2-lyso-sn-glycero-3-phosphocholine = a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + coenzyme A ,
2.3.1.75: a very long chain alcohol + a long-chain acyl-CoA = a wax ester + coenzyme A ,
2.3.1.75: arachidoyl-CoA + 1-dodecanol = arachidoyl dodecanoate + coenzyme A ,
2.3.1.75: a long-chain acyl-CoA + ethanol → a fatty acid-ethyl ester + coenzyme A ,
2.3.1.75: a long-chain acyl-CoA + a long-chain alcohol = a long-chain ester + coenzyme A ,
2.3.1.78: α-D-glucosaminide-[heparan sulfate] + acetyl-CoA = N-acetyl-α-D-glucosaminide-[heparan sulfate] + coenzyme A ,
2.3.1.80: 4-hydroxy-2-nonenal-[L-Cys] conjugate + acetyl-CoA → 4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ ,
2.3.1.80: an L-cysteine-S-conjugate + acetyl-CoA → a mercapturate + coenzyme A + H+ ,
2.3.1.85: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = a long-chain fatty acid + n CO2 + (n+1) coenzyme A + 2n NADP+ ,
2.3.1.87: acetyl-CoA + serotonin → N-acetyl-serotonin + coenzyme A + H+ ,
2.3.1.87: acetyl-CoA + a 2-arylethylamine = an N-acetyl-2-arylethylamine + coenzyme A + H+ ,
2.3.1.97: glycyl-peptide + myristoyl-CoA = N-tetradecanoylglycyl-peptide + coenzyme A ,
2.3.1.108: an [α-tubuline]-L-lysine + acetyl-CoA = an [α-tubulin]-N6-acetyl-L-lysine + coenzyme A + H+ ,
2.3.1.111: an acyl-CoA + n (R)-methylmalonyl-CoA + 2n NADPH + 2n H+ = a multi-methyl-branched acyl-CoA + n CO2 + n coenzyme A + 2n NADP+ ,
2.3.1.118: an N-hydroxy-arylamine + acetyl-CoA = an N-acetoxyarylamine + coenzyme A ,
2.3.1.135: an all-trans retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine → a cellular-retinol-binding protein + an all-trans-retinyl ester + a 1-lysophosphatidylcholine ,
2.3.1.135: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine → a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine ,
2.3.1.137: octanoyl-CoA + L-carnitine = L-octanoylcarnitine + coenzyme A ,
2.3.1.150: salutaridinol + acetyl-CoA → 7-O-acetylsalutaridinol + coenzyme A ,
2.3.1.154: propanoyl-CoA + 4,8,12-trimethyltridecanoyl-CoA = 3-oxopristanoyl-CoA + coenzyme A ,
2.3.1.158: a phosphatidylcholine[out] + a 1,2-diacyl-sn-glycerol[out] → a triacyl-sn-glycerol + a 2-lyso-phosphatidylcholine ,
2.3.1.176: 3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + coenzyme A → choloyl-CoA + propanoyl-CoA ,
2.3.1.176: 3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + coenzyme A → chenodeoxycholoyl-CoA + propanoyl-CoA ,
2.3.1.223: 2,3-didehydroadipyl-CoA + acetyl-CoA = 3-oxo-5,6-didehydrosuberyl-CoA + coenzyme A ,
2.3.1.231: 7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + CO2 + S-adenosyl-L-methionine → wybutosine37 in tRNAPhe + S-adenosyl-L-homocysteine + 2 H+ ,
2.3.1.-: 2 a 1,2-diacyl-sn-glycerol ↔ a triacyl-sn-glycerol + a 2-monoglyceride ,
2.3.1.-: palmitoyl-CoA + malonyl-CoA + H+ → 3-oxo-stearoyl-CoA + CO2 + coenzyme A ,
2.3.2.2: hypoglycin A + glutathione = hypoglycin B + L-cysteinyl-glycine ,
2.3.2.2: glutathione + a standard α amino acid → L-cysteinyl-glycine + an (γ-L-glutamyl)-L-amino acid ,
2.3.2.4: an (γ-L-glutamyl)-L-amino acid → an L-amino acid + 5-oxoproline ,
2.3.3.8: oxaloacetate + acetyl-CoA + ADP + phosphate ← citrate + ATP + coenzyme A ,
2.3.3.10: acetoacetyl-CoA + acetyl-CoA + H2O → (S)-3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ ,
2.3.3.16: oxaloacetate[mitochondrial lumen] + acetyl-CoA[mitochondrial lumen] + H2O[mitochondrial lumen] → citrate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + H+[mitochondrial lumen] ,
2.4.1.1: a glycogen + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: a maltodextrin(n) + phosphate = a maltodextrin(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate = α-D-glucose 1-phosphate + (1,4-α-D-glucosyl)(n-1) ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.1: a debranched limit dextrin + n phosphate → n α-D-glucose 1-phosphate ,
2.4.1.11: UDP-α-D-glucose + (1,4-α-D-glucosyl)(n) glycogenin → (1,4-α-D-glucosyl)(n+1) glycogenin + UDP ,
2.4.1.17: 3,5,3'-triiodo-L-thyronine + UDP-α-D-glucuronate → 3,5,3'-triiodo-L-thyronine phenolic β-D-glucuronide + UDP + H+ ,
2.4.1.17: (S)-nicotine + UDP-α-D-glucuronate → nicotine-glucuronide + UDP ,
2.4.1.17: N-acetyl-serotonin + UDP-α-D-glucuronate → N-acetyl-serotonin glucuronide + UDP ,
2.4.1.17: tetraiodothyroacetate + UDP-α-D-glucuronate → tetraiodothyroacetate ether glucuronide + UDP + H+ ,
2.4.1.17: 3,3',5-triiodothyroacetate + UDP-α-D-glucuronate → triiodothyroacetate ether glucuronide + UDP + H+ ,
2.4.1.17: 5-hydroxytryptophol + UDP-α-D-glucuronate → 5-hydroxytryptophol glucuronide + UDP ,
2.4.1.17: L-thyroxine + UDP-α-D-glucuronate → L-thyroxine phenolic β-D-glucuronide + UDP + H+ ,
2.4.1.17: 3,5,3'-triiodo-L-thyronine + UDP-α-D-glucuronate → 3,5,3'-triiodo-L-thyronine acyl β-D-glucuronide + UDP + H+ ,
2.4.1.17: mycophenolate + UDP-α-D-glucuronate = mycophenolic acid phenolic glucuronide + UDP + H+ ,
2.4.1.17: oleanolate + UDP-α-D-glucuronate = oleanolate 3 β-D-glucuronoside + UDP + H+ ,
2.4.1.17: 3,3',5-triiodothyroacetate + UDP-α-D-glucuronate → triiodothyroacetate ester glucuronide + UDP ,
2.4.1.17: L-thyroxine + UDP-α-D-glucuronate → L-thyroxine acyl β-D-glucuronide + UDP + H+ ,
2.4.1.17: mycophenolate + UDP-α-D-glucuronate = mycophenolic acid O-acyl-glucuronide + UDP ,
2.4.1.17: trans-3'-hydroxycotinine + UDP-α-D-glucuronate → trans-3-hydroxycotinine-glucuronide + UDP + H+ ,
2.4.1.17: a non-glucuronosylated glucuronoside acceptor + UDP-α-D-glucuronate = a glucuronosylated glucuronoside acceptor + UDP ,
2.4.1.17: tetraiodothyroacetate + UDP-α-D-glucuronate → tetraiodothyroacetate ester glucuronide + UDP ,
2.4.1.17: cotinine + UDP-α-D-glucuronate → cotinine-glucuronide + UDP ,
2.4.1.18: a 1,4-α-D-glucan = a glycogen ,
2.4.1.18: a glucosylated glycogenin → a glycogen ,
2.4.1.18: n a 1,4-α-D-glucan = n starch + n H2O ,
2.4.1.22: UDP-α-D-galactose + β-D-glucose = α-lactose + UDP + H+ ,
2.4.1.25: a limit dextrin → a limit dextrin with short branches ,
2.4.1.37: UDP-α-D-galactose + a glycoprotein-α-L-fucosyl-(1,2)-D-galactose = UDP + a galactosyl-(1->3)-[α-L-fucosyl(1->2)]-D-galactosyl-R + H+ ,
2.4.1.38: UDP-α-D-galactose + N-acetyl-β-D-galactosyl-(1,4)-[N-acetyl-β-D-glucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-R → I antigen + UDP + H+ ,
2.4.1.38: UDP-α-D-galactose + an N-acetyl-β-D-glucosaminyl-R → β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.38: UDP-α-D-galactose + N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-R → i antigen + UDP + H+ ,
2.4.1.40: UDP-N-acetyl-D-galactosamine + a glycoprotein-α-L-fucosyl-(1,2)-D-galactose = glycoprotein N-acetyl-α-D-galactosaminyl-(1,3)-[α-L-fucosyl-(1,2)]-D-galactose + UDP + H+ ,
2.4.1.41: UDP-N-acetyl-α-D-galactosamine + a [glycoprotein]-(L-serine/L-threonine) → N-acetyl-α-D-galactosalaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.45: UDP-α-D-galactose + a 2-(2-hydroxyacyl)sphingosine = a 1-(β-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP + H+ ,
2.4.1.50: UDP-α-D-galactose + a [procollagen]-5-hydroxy-L-lysine = a procollagen 5-(galactosyloxy)-L-lysine + UDP + H+ ,
2.4.1.62: UDP-α-D-galactose + gangloside GM2 = ganglioside GM1a + UDP + H+ ,
2.4.1.65: GDP-L-fucose + 1,3-β-D-galactosyl-N-acetyl-D-glucosaminyl-R = 1,3-β-D-galactosyl-(α-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl- R + GDP + H+ ,
2.4.1.68: GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine = GDP + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-[α-L-fucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl}asparagine + H+ ,
2.4.1.69: GDP-L-fucose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide = III2-α-fucosyllactotetraosylceramide + GDP + H+ ,
2.4.1.79: UDP-N-acetyl-α-D-galactosamine + an α-D-galactosyl-(1->4)-β-D-galactosyl-(1->4)-β-D-glucosylceramide = an N-acetyl-β-D-galactosaminyl-(1,3)-α-D-galactosyl-(1,4)-β-D-galactosyl-(1,4)-β-D-glucosylceramide + UDP + H+ ,
2.4.1.80: UDP-α-D-glucose + an N-acylsphingosine + H+ = a D-glucosyl-N-acylsphinganine + UDP ,
2.4.1.80: UDP-α-D-glucose + a dihydroceramide = a D-glucosyl-N-acylsphinganine + UDP + H+ ,
2.4.1.83: a dolichyl phosphate + GDP-α-D-mannose → a dolichyl β-D-mannosyl phosphate + GDP ,
2.4.1.87: UDP-α-D-galactose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-D-galactosyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R + UDP + H+ ,
2.4.1.90: UDP-α-D-galactose + N-acetyl-β-D-glucosamine = β-D-galactosyl-1,4-N-acetyl-β-D-glucosamine + UDP + H+ ,
2.4.1.92: UDP-N-acetyl-α-D-galactosamine + a 1-O-[O-(N-acetyl-α-neuraminyl)-2,3-β-D-galactosyl-1,4-β-D-glucosyl]ceramide = gangloside GM2 + UDP + H+ ,
2.4.1.101: UDP-N-acetyl-α-D-glucosamine + a (mannosyl)5-N-glycan = a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan + UDP + H+ ,
2.4.1.102: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine → β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.117: UDP-α-D-glucose + a dolichyl phosphate → a dolichyl β-D-glucosyl phosphate + UDP ,
2.4.1.122: UDP-α-D-galactose + N-acetyl-α-D-galactosalaminyl-[glycoprotein] → β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + UDP + H+ ,
2.4.1.131: a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol + 2 GDP-α-D-mannose → a (mannosyl)5-(N-acetylglucosaminyl)2-diphosphodolichol + 2 GDP + 2 H+ ,
2.4.1.132: a mannosyl-(N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.133: UDP-α-D-galactose + O-β-D-xylosyl-[core protein] → β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.141: an N-acetylglucosaminyl-diphosphodolichol + UDP-N-acetyl-α-D-glucosamine → an (N-acetylglucosaminyl)2-diphosphodolichol + UDP + H+ ,
2.4.1.142: an (N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a mannosyl-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.143: α-D-mannosyl-1,6-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3)-β-D-mannosyl-[glycoprotein] + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3)-β-D-mannosyl-[glycoprotein] + UDP + H+ ,
2.4.1.144: N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-(N-acetyl-β-D-glucosaminyl-1,4)-β-D-mannosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.145: (N-acetyl-β-D-glucosaminyl-1,2)-α-D-mannosyl-1,3-(β-N-acetyl-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-R + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-α-D-mannosyl-1,3-(β-N-acetyl-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-R + UDP + H+ ,
2.4.1.146: β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP-N-acetyl-α-D-glucosamine → N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.149: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.150: UDP-N-acetyl-α-D-glucosamine + i antigen → N-acetyl-β-D-galactosyl-(1,4)-[N-acetyl-β-D-glucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.150: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → N-acetyl-β-D-glucosaminyl-(1→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.152: GDP-L-fucose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → Lewis x epitope + GDP + H+ ,
2.4.1.155: [(2,4),(2)]-N-linked glycan + UDP-N-acetyl-α-D-glucosamine = [(2,4),(2,6)]-N-linked glycan + UDP + H+ ,
2.4.1.174: UDP-N-acetyl-D-galactosamine + β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] = α-N-acetyl-D-galactosaminyl-(1->4)-β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.174: UDP-N-acetyl-D-galactosamine + D-glucuronyl-1,3-β-D-galactosylproteoglycan → N-acetyl-D-galactosaminyl-1,4-β-D-glucuronyl-1,3-β-D-galactosyl-[proteoglycan] + UDP + H+ ,
2.4.1.175: UDP-N-acetyl-α-D-galactosamine + β-D-glucuronosyl-[chondroitin/dermatan] → N-acetyl-β-D-galactosaminide-[chondroitin/dermatan] + UDP + H+ ,
2.4.1.198: an L-1-phosphatidyl-inositol + UDP-N-acetyl-α-D-glucosamine = a 6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + UDP + H+ ,
2.4.1.212: N-acetyl-α-D-glucosaminide-[hyaluronan] + UDP-α-D-glucuronate = β-D-glucuronosyl-[hyaluronan] + UDP ,
2.4.1.212: UDP-N-acetyl-α-D-glucosamine + β-D-glucuronosyl-[hyaluronan] = N-acetyl-α-D-glucosaminide-[hyaluronan] + UDP ,
2.4.1.214: GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine = N(4)-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-[α-L-fucosyl-(1,3)]-N-acetyl-β-D-glucosaminyl}asparagine + GDP + H+ ,
2.4.1.221: GDP-β-L-fucose + a [protein]-L-serine = GDP + a [protein]-3-O-L-fucosyl-L-serine + H+ ,
2.4.1.222: UDP-N-acetyl-α-D-glucosamine + a fucosyl-protein = UDP + O-β-D-GlcNAc-fucosyl-protein ,
2.4.1.223: β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP-N-acetyl-α-D-glucosamine → α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.224: β-D-glucuronosyl-[heparan sulfate] + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-glucosaminide-[heparan sulfate] + UDP + H+ ,
2.4.1.225: N-acetyl-α-D-glucosaminide-[heparan sulfate] + UDP-α-D-glucuronate → β-D-glucuronosyl-[heparan sulfate] + UDP ,
2.4.1.226: N-acetyl-β-D-galactosaminide-[chondroitin/dermatan] + UDP-α-D-glucuronate → β-D-glucuronosyl-[chondroitin/dermatan] + UDP ,
2.4.1.228: UDP-α-D-galactose + a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide = an α-D-galactosyl-(1->4)-β-D-galactosyl-(1->4)-β-D-glucosylceramide + UDP + H+ ,
2.4.1.244: UDP-N-acetyl-α-D-galactosamine + an N-acetyl-β-D-glucosaminyl-R = N-acetyl-β-D-galactosaminyl-(1->4)-N-acetyl-β-D-glucosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) → UDP + an N-acetyl-α-D-glucosaminyl-[glycoprotein] + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [protein]-L-threonine = UDP + an N-acetyl-α-D-glucosaminyl-L-threonine-[glycoprotein] + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [protein]-L-serine = UDP + an N-acetyl-α-D-glucosaminyl-L-serine-[glycoprotein] + H+ ,
2.4.1.256: a (glucosyl)2(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → dolichyl diphosphooligosaccharide + a dolichyl phosphate + H+ ,
2.4.1.257: a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.258: a (mannosyl)5-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.259: a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.260: a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.261: a (mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.265: a glucosyl-(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → a (glucosyl)2(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.267: a (mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → a glucosyl-(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.274: UDP-α-D-galactose + a D-glucosyl-N-acylsphingosine = a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.1.275: an N-acetyl-β-D-glucosaminyl-(1-3)-β-D-galactosyl-(1-4)-β-D-glucosyl-(1↔1)-ceramide + UDP-α-D-galactose = a β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1-3)-β-D-galactosyl-1,4-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.1.-: an N-acetyl-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide + UDP-α-D-galactose = β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.2.1: a purine ribonucleoside + arsenate → ribose-1-arsenate + a purine base ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine ,
2.4.2.1: xanthosine + phosphate ↔ α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: a purine ribonucleoside + phosphate = α-D-ribose-1-phosphate + a purine base ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine ,
2.4.2.2/2.4.2.4: thymidine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + thymine ,
2.4.2.2/2.4.2.3: uridine + phosphate ↔ α-D-ribose-1-phosphate + uracil ,
2.4.2.3: 2'-deoxyuridine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + uracil ,
2.4.2.7: AMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + adenine ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + hypoxanthine ,
2.4.2.9: UMP + diphosphate = 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.12: β-nicotinamide D-ribonucleotide + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + nicotinamide + H+ ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.26: a core protein L-serine + UDP-α-D-xylose → O-β-D-xylosyl-[core protein] + UDP ,
2.4.2.28: S-methyl-5'-thioadenosine + phosphate → S-methyl-5-thio-α-D-ribose 1-phosphate + adenine ,
2.4.2.31: a [protein]-L-arginine + NAD+ = a protein-Nω-(ADP-D-ribosyl)-L-arginine + nicotinamide + H+ ,
2.4.2.36: a diphthamide-[translation elongation factor 2] + NAD+ = N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide ,
2.4.99.1: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-N-acetylneuraminyl-2,6-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + CMP + H+ ,
2.4.99.4: β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + CMP-N-acetyl-β-neuraminate → α-N-acetylneuraminyl-2,3-β-D-galactosyl-1,3-N-acetyl-α-D-galactosaminyl-[glycoprotein] + CMP + H+ ,
2.4.99.6: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + CMP + H+ ,
2.4.99.7: α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-[(α-N-acetylneuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP + H+ ,
2.4.99.8: α-N-acetylneuraminyl-2,3-β-D-galactosyl-R + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-2,8-α-N-acetylneuraminyl-2,3-β-D-galactosyl-R + CMP ,
2.4.99.9: a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP-N-acetyl-β-neuraminate = a 1-O-[O-(N-acetyl-α-neuraminyl)-2,3-β-D-galactosyl-1,4-β-D-glucosyl]ceramide + CMP ,
2.4.99.10: β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosylceramide + CMP + H+ ,
2.4.99.20: nicotinate + NADP+ = nicotinate-adenine dinucleotide phosphate + nicotinamide ,
2.4.99.-: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1->3)-N-acetyl-α-D-galactosaminyl-R = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP + H+ ,
2.4.99.-: β-D-galactosyl-(1->3)-N-acetyl-β-D-glucosaminyl-R[Golgi lumen] + CMP-N-acetyl-β-neuraminate[Golgi lumen] = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R[Golgi lumen] + CMP[Golgi lumen] + H+[Golgi lumen] ,
2.5.1.1: dimethylallyl diphosphate + isopentenyl diphosphate → geranyl diphosphate + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.10: geranyl diphosphate + isopentenyl diphosphate → (2E,6E)-farnesyl diphosphate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.17: cobinamide + ATP = adenosylcobinamide + PPPi ,
2.5.1.17: ATP + cob(I)alamin = coenzyme B12 + PPPi ,
2.5.1.17: cob(I)yrinate a,c-diamide + ATP = adenosyl-cobyrinate a,c-diamide + PPPi ,
2.5.1.18: glutathione + 4-hydroxy-2-nonenal → 4-hydroxy-2-nonenal-glutathione conjugate ,
2.5.1.18: 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H+ ,
2.5.1.18: glutathione + RX → a glutathione-toxin conjugate + HX ,
2.5.1.21: 2 (2E,6E)-farnesyl diphosphate + NAD(P)H + H+ → squalene + NAD(P)+ + 2 diphosphate ,
2.5.1.22: spermidine + S-adenosyl 3-(methylthio)propylamine → spermine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.26: an acylglycerone phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain carboxylate ,
2.5.1.29: isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate → geranylgeranyl diphosphate + diphosphate ,
2.5.1.32: 2 2-cis,6-trans,10-trans-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate ,
2.5.1.39: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate → 3-decaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.56: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = N-acetyl-β-neuraminate + phosphate ,
2.5.1.57: N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O → N-acetyl-β-neuraminate 9-phosphate + phosphate ,
2.5.1.58: a [protein]-L-cysteine + (2E,6E)-farnesyl diphosphate = a [protein]-S-farnesyl-L-cysteine + diphosphate ,
2.5.1.60: geranylgeranyl diphosphate + a [protein]-L-cysteine = a [protein]-S-geranylgeranyl-L-cysteine + diphosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.87: (2E,6E)-farnesyl diphosphate + 13 isopentenyl diphosphate → di-trans, poly-cis-polyprenyl diphosphate (C80) + 13 diphosphate ,
2.5.1.91: (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate → all-trans-decaprenyl diphosphate + 7 diphosphate ,
2.5.1.99: 2 geranylgeranyl diphosphate = all-trans-phytoene + 2 diphosphate ,
2.5.1.103: 2 (2E,6E)-farnesyl diphosphate = presqualene diphosphate + diphosphate ,
2.5.1.108: an L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H+ ,
2.5.1.114: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPheS-methyl-5'-thioadenosine + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe + H+ ,
2.5.1.-: heme b + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate ,
2.6.1.1: L-aspartate[mitochondrial lumen] + 2-oxoglutarate[mitochondrial lumen] = L-glutamate[mitochondrial lumen] + oxaloacetate[mitochondrial lumen] ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ oxaloacetate + L-glutamate ,
2.6.1.2: 2-oxoglutarate + L-alanine → L-glutamate + pyruvate ,
2.6.1.3: 2-oxoglutarate + L-cysteine → L-glutamate + 3-mercaptopyruvate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate → 4-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.7: L-kynurenine + 2-oxoglutarate ↔ L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate ,
2.6.1.7: 3-hydroxy-L-kynurenine + 2-oxoglutarate ↔ 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate ,
2.6.1.13: L-ornithine + a 2-oxo carboxylate = a standard α amino acid + L-glutamate-5-semialdehyde ,
2.6.1.13: L-ornithine + 2-oxoglutarate ↔ L-glutamate + L-glutamate-5-semialdehyde ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.19: 2-oxoglutarate + 4-aminobutanoate → L-glutamate + succinate semialdehyde ,
2.6.1.19: 2-oxoglutarate + β-alanine ↔ L-glutamate + malonate semialdehyde ,
2.6.1.22: 2-oxoglutarate + (S)-3-amino-2-methylpropanoate ↔ L-glutamate + (S)-methylmalonate-semialdehyde ,
2.6.1.23: 2-oxoglutarate + erythro-4-hydroxy-L-glutamate ↔ L-glutamate + 4-hydroxy-2-oxoglutarate ,
2.6.1.39: 2-oxoglutarate + L-2-aminoadipate → L-glutamate + 2-oxoadipate ,
2.6.1.40: pyruvate + (R)-3-amino-2-methylpropanoate ↔ L-alanine + (S)-methylmalonate-semialdehyde ,
2.6.1.42: L-isoleucine + 2-oxoglutarate → (S)-3-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.42: L-valine + 2-oxoglutarate → 3-methyl-2-oxobutanoate + L-glutamate ,
2.6.1.44: glyoxylate + L-alanine ↔ glycine + pyruvate ,
2.6.1.49: L-dopa + 2-oxoglutarate ↔ 3,4-dihydroxyphenylpyruvate + L-glutamate ,
2.6.1.51: pyruvate + L-serine ↔ L-alanine + hydroxypyruvate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate = 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ← 3-phospho-hydroxypyruvate + L-glutamate ,
2.6.1.57: 2-oxoglutarate + L-tyrosine → L-glutamate + 4-hydroxyphenylpyruvate ,
2.6.1.64: 2-oxo-3-phenylpropanoate + L-glutamine ↔ L-phenylalanine + 2-oxoglutaramate ,
2.6.1.82: 4-aminobutanal ↔ 1-pyrroline + H2O ,
2.6.1.88: L-methionine + a 2-oxo carboxylate ← 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.1.-: L-methionine + 2-oxoglutaramate ↔ 2-oxo-4-methylthiobutanoate + L-glutamine ,
2.6.1.-: 3-sulfinoalanine + 2-oxoglutarate ↔ L-glutamate + 3-sulfinopyruvate ,
2.7.1.1: a D-hexose + ATP = D-hexose 6-phosphate + ADP + H+ ,
2.7.1.1/2.7.1.2: α-D-glucose + ATP = α-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.2: D-glucopyranose + ATP → D-glucopyranose 6-phosphate + ADP + H+ ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.3: β-D-fructofuranose + ATP → β-D-fructofuranose 1-phosphate + ADP + H+ ,
2.7.1.6: α-D-galactose + ATP → α-D-galactose 1-phosphate + ADP + H+ ,
2.7.1.7: D-mannopyranose + ATP → α-D-mannose 6-phosphate + ADP + H+ ,
2.7.1.11: ATP + β-D-fructofuranose 6-phosphate → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.12: ATP + D-gluconate = D-gluconate 6-phosphate + ADP + H+ ,
2.7.1.14: D-sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H+ ,
2.7.1.15: α-D-ribofuranose + ATP = α-D-ribose 5-phosphate + ADP + H+ ,
2.7.1.17: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H+ ,
2.7.1.20: adenosine + ATP → AMP + ADP + H+ ,
2.7.1.22: 1-(β-D ribofuranosyl)nicotinamide + ATP = β-nicotinamide D-ribonucleotide + ADP + H+ ,
2.7.1.23: ATP + NAD+ → ADP + NADP+ + H+ ,
2.7.1.24: 3'-dephospho-CoA + ATP → ADP + coenzyme A + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP → 3'-phosphoadenylyl-sulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.28: D-glyceraldehyde + ATP → D-glyceraldehyde 3-phosphate + ADP + H+ ,
2.7.1.29: dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.31: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → (R)-4'-phosphopantothenate + ADP + H+ ,
2.7.1.35: ATP + pyridoxine → ADP + pyridoxine 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxal → ADP + pyridoxal 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxamine → ADP + pyridoxamine 5'-phosphate + H+ ,
2.7.1.36: (R)-mevalonate + ATP → (R)-mevalonate 5-phosphate + ADP + H+ ,
2.7.1.40: pyruvate + ATP ← phosphoenolpyruvate + ADP + H+ ,
2.7.1.48: cytidine + GTP = CMP + GDP + H+ ,
2.7.1.48: uridine + ATP → UMP + ADP + H+ ,
2.7.1.48: cytidine + ATP → CMP + ADP + H+ ,
2.7.1.48: uridine + GTP = UMP + GDP + H+ ,
2.7.1.52: L-fucopyranose + ATP → β-L-fucose 1-phosphate + ADP + H+ ,
2.7.1.59: N-acetyl-β-D-glucosamine + ATP → N-acetyl-D-glucosamine 6-phosphate + ADP + H+ ,
2.7.1.60: N-acetyl-D-mannosamine + ATP → N-acetyl-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.60: an N-acyl-D-mannosamine + ATP = an N-acyl-α-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.67: an L-1-phosphatidyl-inositol + ATP → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + H+ ,
2.7.1.68: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+ ,
2.7.1.74/2.7.1.76/2.7.1.145: 2'-deoxyadenosine + ATP → dAMP + ADP + H+ ,
2.7.1.74/2.7.1.113/2.7.1.145: 2'-deoxyguanosine + ATP → dGMP + ADP + H+ ,
2.7.1.74: 2'-deoxycytidine + a nucleoside triphosphate → dCMP + a nucleoside diphosphate + H+ ,
2.7.1.82: ethanolamine + ATP → phosphoryl-ethanolamine + ADP + H+ ,
2.7.1.91: sphinganine + ATP = sphinganine 1-phosphate + ADP + H+ ,
2.7.1.94: a 1-monoglyceride + ATP = a 1-acyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.105: β-D-fructofuranose 6-phosphate + ATP → β-D-fructose 2,6-bisphosphate + ADP + H+ ,
2.7.1.106: α-D-glucose 1-phosphate + 1,3-bisphospho-D-glycerate = α-glucose 1,6-bisphosphate + 3-phospho-D-glycerate + H+ ,
2.7.1.107: ATP + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.108: a dolichol + CTP → a dolichyl phosphate + CDP + H+ ,
2.7.1.127: D-myo-inositol (1,4,5)-trisphosphate + ATP → D-myo-inositol (1,3,4,5)-tetrakisphosphate + ADP + H+ ,
2.7.1.134: D-myo-inositol (3,4,5,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.137: an L-1-phosphatidyl-inositol + ATP → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+ ,
2.7.1.138: a dihydroceramide + ATP = a dihydroceramide 1-phosphate + ADP + H+ ,
2.7.1.138: a ceramide + ATP = a ceramide 1-phosphate + ADP + H+ ,
2.7.1.140: D-myo-inositol (1,3,4,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.145: 2'-deoxyuridine + ATP → dUMP + ADP + H+ ,
2.7.1.145: thymidine + ATP → dTMP + ADP + H+ ,
2.7.1.32: choline + ATP → phosphocholine + ADP + H+ ,
2.7.1.147: D-glucosamine + ADP = D-glucosamine 6-phosphate + AMP + H+ ,
2.7.1.147: β-D-glucose + ADP = β-D-glucose 6-phosphate + AMP + H+ ,
2.7.1.149: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+ ,
2.7.1.150: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP → 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + H+ ,
2.7.1.151: D-myo-inositol (1,4,5,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.151: D-myo-inositol (1,3,4,5)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.153: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP → 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+ ,
2.7.1.154: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+ ,
2.7.1.157: ATP + N-acetyl-α-D-galactosamine = ADP + N-acetyl-α-D-galactosamine 1-phosphate + H+ ,
2.7.1.158: D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP → 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ADP + H+ ,
2.7.1.159: D-myo-inositol (1,3,4)-trisphosphate + ATP → D-myo-inositol (1,3,4,6)-tetrakisphosphate + ADP + H+ ,
2.7.1.159: D-myo-inositol (1,3,4)-trisphosphate + ATP → D-myo-inositol (1,3,4,5)-tetrakisphosphate + ADP + H+ ,
2.7.1.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP → a diphospho-1D-myo-inositol tetrakisphosphate + ADP ,
2.7.1.-: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+ ,
2.7.1.-: an N-acetyl-D-galactosamine + ATP = N-acetyl-D-galactosamine 6-phosphate + ADP + H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.11: L-glutamate[mitochondrial lumen] + ATP[mitochondrial lumen] → γ-L-glutamyl 5-phosphate[mitochondrial lumen] + ADP[mitochondrial lumen] ,
2.7.3.2: creatine + ATP ↔ creatine-phosphate + ADP + H+ ,
2.7.4.2: (R)-mevalonate 5-phosphate + ATP ↔ (R)-mevalonate diphosphate + ADP ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP = a nucleoside triphosphate + ADP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.10: a nucleoside triphosphate + AMP = a nucleoside diphosphate + ADP ,
2.7.4.12/2.7.4.13: dTMP + ATP → ADP + dTDP ,
2.7.4.13: ATP + dAMP → ADP + dADP ,
2.7.4.13: ATP + dGMP → ADP + dGDP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.21: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ADP ,
2.7.4.21: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + ADP ,
2.7.4.21/2.7.4.24: 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + ATP → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.4.24: 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + ATP → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.24: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ATP → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.24: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + ADP ,
2.7.4.24: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ATP → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.6.1: D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.2: thiamin + ATP → thiamin diphosphate + AMP + H+ ,
2.7.7.1: β-nicotinamide D-ribonucleotide + ATP + H+ → NAD+ + diphosphate ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.3: 4'-phosphopantetheine + ATP + H+ → 3'-dephospho-CoA + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ = UDP-α-D-glucose + diphosphate ,
2.7.7.10: α-D-galactose 1-phosphate + UTP + H+ = UDP-α-D-galactose + diphosphate ,
2.7.7.12: UDP-α-D-glucose + α-D-galactose 1-phosphate → UDP-α-D-galactose + α-D-glucose 1-phosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.14: phosphoryl-ethanolamine + CTP + H+ → CDP-ethanolamine + diphosphate ,
2.7.7.15: phosphocholine + CTP + H+ → CDP-choline + diphosphate ,
2.7.7.18: ATP + β-nicotinate D-ribonucleotide + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.22: α-D-mannose 1-phosphate + GDP + H+ = GDP-α-D-mannose + phosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.30: β-L-fucose 1-phosphate + GTP + H+ → GDP-L-fucose + diphosphate ,
2.7.7.34: α-D-glucose 1-phosphate + GTP + H+ → GDP-α-D-glucose + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.43: N-acetyl-β-neuraminate + CTP → CMP-N-acetyl-β-neuraminate + diphosphate ,
2.7.7.43: an N-acyl-β-neuraminate + CTP + H+ = a CMP-N-acyl-β-neuraminate + diphosphate ,
2.7.7.50: a 5'-diphospho-purine-[mRNA] + GTP + H+ → a 5'-(5'-triphosphoguanosine)-purine-[mRNA] + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate = a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.75: ATP + molybdopterin + H+ → molybdopterin adenine dinucleotide + diphosphate ,
2.7.7.78: GDP-α-D-glucose + phosphate ↔ α-D-glucose 1-phosphate + GDP + H+ ,
2.7.7.84: 3 ATP + H+ → pppA2'p5'A2'p5'A + 2 diphosphate ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.1: a 1,2-diacyl-sn-glycerol + CDP-ethanolamine → an L-1-phosphatidyl-ethanolamine + CMP + H+ ,
2.7.8.2: a 1,2-diacyl-sn-glycerol + CDP-choline → a phosphatidylcholine + CMP + H+ ,
2.7.8.2: 1,2-dipalmitoylglycerol + CDP-choline → 1,2-dipalmitoyl-phosphatidylcholine + CMP + H+ ,
2.7.8.5: a CDP-diacylglycerol + sn-glycerol 3-phosphate → CMP + an L-1-phosphatidylglycerol-phosphate + H+ ,
2.7.8.11: a CDP-diacylglycerol + myo-inositol → an L-1-phosphatidyl-inositol + CMP + H+ ,
2.7.8.15: a dolichyl phosphate + UDP-N-acetyl-α-D-glucosamine → an N-acetylglucosaminyl-diphosphodolichol + UMP ,
2.7.8.17: a lysosomal-enzyme-D-mannose + UDP-N-acetyl-α-D-glucosamine = a lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose + UMP ,
2.7.8.27: a ceramide + a phosphatidylcholine ↔ a sphingomyelin + a 1,2-diacyl-sn-glycerol ,
2.7.8.29: an L-1-phosphatidyl-ethanolamine + L-serine → an L-1-phosphatidylserine + ethanolamine ,
2.7.8.-: a phosphatidylcholine + L-serine = an L-1-phosphatidylserine + choline ,
2.7.8.-: 2 an L-1-phosphatidyl-glycerol = a cardiolipin + glycerol ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.7.10.2/2.7.12.1: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate + H+ ,
2.7.11.18: ATP + myosin light-chain + H+ = ADP + myosin light-chain phosphate ,
2.8.1.1: hydrogen cyanide + thiosulfate → sulfite + thiocyanate + 2 H+ ,
2.8.1.2: hydrogen cyanide + 3-mercaptopyruvate → pyruvate + thiocyanate + H+ ,
2.8.1.7: an [L-cysteine desulfurase] + L-cysteine → an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.7: an [L-cysteine desulfurase] L-cysteine persulfide + an unsulfurated [sulfur carrier] ↔ an [L-cysteine desulfurase]-L-cysteine + a sulfurated [sulfur carrier] ,
2.8.1.7: an [L-cysteine desulfurase]-L-cysteine + L-cysteine → an [L-cysteine desulfurase] L-cysteine persulfide + L-alanine ,
2.8.1.7: a [cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-cysteine → an S-sulfanyl-[cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-alanine ,
2.8.1.7: L-cysteine + an unsulfurated [sulfur carrier] → L-alanine + a sulfurated [sulfur carrier] ,
2.8.1.9: MoO2-molybdopterin cofactor + L-cysteine + 2 H+ → thio-molybdenum cofactor + L-alanine + H2O ,
2.8.1.12: cyclic pyranopterin phosphate + 2 a thiocarboxylated small subunit of molybdopterin synthase + H2O → 2 a small subunit of molybdopterin synthase + molybdopterin ,
2.8.2.1: serotonin + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + serotonin O-sulfate + H+ ,
2.8.2.1: dopamine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H+ ,
2.8.2.1: 3'-phosphoadenylyl-sulfate + 4-methylphenol = adenosine 3',5'-bisphosphate + 4-methylphenyl sulfate + H+ ,
2.8.2.1: a phenol + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + an aryl sulfate ,
2.8.2.1: N-acetyl-serotonin + 3'-phosphoadenylyl-sulfate → N-acetyl-serotonin sulfate + adenosine 3',5'-bisphosphate ,
2.8.2.1: 3,5,3'-triiodo-L-thyronine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + triiodothyronine sulfate + H+ ,
2.8.2.1: 5-hydroxytryptophol + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + 5-hydroxytryptophol sulfate + H+ ,
2.8.2.1: 3'-phosphoadenylyl-sulfate + indoxyl = adenosine 3',5'-bisphosphate + indoxyl sulfate + H+ ,
2.8.2.1: 6-hydroxymelatonin + 3'-phosphoadenylyl-sulfate → 6-sulfatoxymelatonin + adenosine 3',5'-bisphosphate ,
2.8.2.1: L-thyroxine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + thyroxine sulfate + H+ ,
2.8.2.2: an alcohol + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + an organosulfate + H+ ,
2.8.2.4: estrone + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + estrone-sulfate + H+ ,
2.8.2.5: [chondroitin]-N-acetyl-galactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-4-O-sulfo-N-acetylgalactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.8: [heparan sulfate]-α-D-glucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine + adenosine 3',5'-bisphosphate ,
2.8.2.11: a cerebroside + 3'-phosphoadenylyl-sulfate = a cerebroside 3-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.14: taurolithocholate + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate + H+ ,
2.8.2.14: glycolithocholate + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + glycolithocholate-3-sulfate + H+ ,
2.8.2.17: [chondroitin]-N-acetyl-galactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-6-O-sulfo-N-acetylgalactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.21: a keratan + 3'-phosphoadenylyl-sulfate = keratan sulfate + adenosine 3',5'-bisphosphate ,
2.8.2.23: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.29: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.30: [heparan sulfate]-α-D-glucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-glucosamine 3-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.33: [chondroitin]-4-O-sulfo-N-acetylgalactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-4,6-di-O-sulfo-N-acetyl-D-galactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.33: [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine + 3'-phosphoadenylyl-sulfate → [dermatan]-4,6-di-O-sulfo-N-acetyl-D-galactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.35: [dermatan]-N-acetyl-D-galactosamine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine + H+ ,
2.8.2.-: [dermatan]-α-L-iduronate + 3'-phosphoadenylyl-sulfate → [dermatan-sulfate]-2-O-sulfo-α-L-iduronate + adenosine 3',5'-bisphosphate ,
2.8.2.-: [heparan-sulfate]-α-L-iduronate + 3'-phosphoadenylyl-sulfate → [heparan-sulfate]-2-O-sulfo-α-L-iduronate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 6-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan-sulfate]-β-D-glucuronate + 3'-phosphoadenylyl-sulfate = [heparan-sulfate]-2-O-sulfo-β-D-glucuronate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan sulfate]-α-D-N-sulfoglucosamine 6-O-sulfate + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3,6-O-bissulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [chondroitin-sulfate]-β-D-glucuronate + 3'-phosphoadenylyl-sulfate → [chondroitin-sulfate]-2-O-sulfo-β-D-glucuronate + adenosine 3',5'-bisphosphate ,
2.8.3.5: a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate ,
2.8.3.5: succinyl-CoA + acetoacetate → succinate + acetoacetyl-CoA ,
2.10.1.1: molybdopterin adenine dinucleotide + molybdate + H+ → MoO2-molybdopterin cofactor + AMP + H2O ,
3.1.1.1: an all-trans-retinyl ester + H2O → all-trans-retinol + a long-chain fatty acid + H+ ,
3.1.1.1: methyl (indol-3-yl)acetate + H2O → indole-3-acetate + methanol + H+ ,
3.1.1.1: all-trans-retinyl palmitate + H2O → all-trans-retinol + palmitate + H+ ,
3.1.1.1: a carboxylic ester + H2O ↔ an alcohol + a carboxylate + H+ ,
3.1.1.1: all-trans-retinyl palmitate + H2O → a retinol + palmitate + H+ ,
3.1.1.1: a methyl jasmonate + H2O → a jasmonic acid + methanol + H+ ,
3.1.1.1: salicyl-6-hydroxy-2-cyclohexene-on-oyl + H2O → 6-hydroxy-2-cyclohexen-one-carboxylate + salicyl alcohol + H+ ,
3.1.1.1: 1-O-methylsalicylate + H2O → salicylate + methanol + H+ ,
3.1.1.2: a phenyl acetate + H2O → a phenol + acetate + H+ ,
3.1.1.3: a triglyceride + H2O → a 1,2-diglyceride + a fatty acid + H+ ,
3.1.1.3: a dietary all-trans-retinyl ester + H2O → all-trans-retinol + a long-chain fatty acid + H+ ,
3.1.1.3: tributyrin + H2O → 1,2-dibutyrin + butanoate + H+ ,
3.1.1.4: a phosphatidylcholine + H2O → a 2-lyso-phosphatidylcholine + a fatty acid + H+ ,
3.1.1.4: an L-1-phosphatidyl-ethanolamine + H2O → a fatty acid + a 2-lyso-phosphatidyl-ethanolamine + H+ ,
3.1.1.4: a phosphatidylcholine + H2O → a 2-lyso-phosphatidylcholine + α-linolenate ,
3.1.1.5: a 1-lysophosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+ ,
3.1.1.7: acetylcholine + H2O → acetate + choline + H+ ,
3.1.1.8: an acylcholine + H2O → choline + a carboxylate + H+ ,
3.1.1.13: a steryl-ester + H2O → a sterol + a fatty acid + H+ ,
3.1.1.17: D-glucono-1,5-lactone + H2O → D-gluconate + H+ ,
3.1.1.23: a 1-monoglyceride + H2O → a fatty acid + glycerol + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.1.32: a phosphatidylcholine + H2O → a 1-lysophosphatidylcholine + a fatty acid + H+ ,
3.1.1.34/3.1.1.79: a 1,2-diglyceride + H2O → a 2-monoglyceride + a fatty acid + H+ ,
3.1.1.34: a triacyl-sn-glycerol + H2O = a carboxylate + a 1,2-diacyl-sn-glycerol + H+ ,
3.1.1.45: trans-dienelactone + H2O → 2-maleylacetate + H+ ,
3.1.1.45: cis-dienelactone + H2O → 2-maleylacetate + H+ ,
3.1.1.47: a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O → acetate + a 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + H+ ,
3.1.1.52: an L-1-phosphatidyl-inositol + H2O → 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H+ ,
3.1.1.53: N-acetyl-4-O-acetylneuraminate + H2O → N-acetylneuraminate + acetate + H+ ,
3.1.1.56: 4-methylumbelliferyl acetate + H2O → acetate + 4-methylumbelliferone + H+ ,
3.1.1.77: a 3-(acyloxy)acyl group of bacterial toxin + H2O → a 3-hydroxyacyl group of bacterial toxin + a fatty acid + H+ ,
3.1.1.79: a 2-monoglyceride + H2O → glycerol + a fatty acid + H+ ,
3.1.1.89: a [phosphatase 2A protein] C-terminal L-leucine methyl ester + H2O → a [phosphatase 2A protein] C-terminal L-leucine + methanol + H+ ,
3.1.1.93: mycophenolic acid O-acyl-glucuronide + H2O → mycophenolate + D-glucopyranuronate + H+ ,
3.1.1.-: [heparan sulfate]-N-acetyl-α-D-glucosamine + H2O → [heparan sulfate]-α-D-glucosamine + acetate + H+ ,
3.1.2.1: acetyl-CoA + H2O → acetate + coenzyme A + H+ ,
3.1.2.2: decanoyl-CoA + H2O → decanoate + coenzyme A + H+ ,
3.1.2.2: a 2,3,4-saturated fatty acyl CoA + H2O → a 2,3,4-saturated fatty acid + coenzyme A + H+ ,
3.1.2.2: lauroyl-CoA + H2O → laurate + coenzyme A + H+ ,
3.1.2.2: eicosapentaenoyl-CoA + H2O → icosapentaenoate + coenzyme A + H+ ,
3.1.2.2: myristoyl-CoA + H2O → myristate + coenzyme A + H+ ,
3.1.2.2: arachidoyl-CoA + H2O → arachidate + coenzyme A + H+ ,
3.1.2.2: palmitoyl-CoA + H2O → palmitate + coenzyme A + H+ ,
3.1.2.2: stearoyl-CoA + H2O → stearate + coenzyme A + H+ ,
3.1.2.3: succinyl-CoA + H2O → succinate + coenzyme A + H+ ,
3.1.2.4: 3-hydroxypropanoyl-CoA + H2O → 3-hydroxypropanoate + coenzyme A + H+ ,
3.1.2.4: 3-hydroxy-isobututanoyl-CoA + H2O → 3-hydroxy-isobutyrate + coenzyme A + H+ ,
3.1.2.4: (S)-3-hydroxy-isobutanoyl-CoA + H2O → (S)-3-hydroxy-isobutanoate + coenzyme A + H+ ,
3.1.2.6: S-(2-hydroxyacyl)glutathione + H2O → glutathione + a 2-hydroxy carboxylate ,
3.1.2.6: (R)-S-lactoylglutathione + H2O → glutathione + (R)-lactate + H+ ,
3.1.2.10: formyl-CoA + H2O → formate + coenzyme A + H+ ,
3.1.2.12: S-formylglutathione + H2O → formate + glutathione + H+ ,
3.1.2.20: an acyl-CoA + H2O → a carboxylate + coenzyme A + H+ ,
3.1.2.23: 4-hydroxybenzoyl-CoA + H2O → 4-hydroxybenzoate + coenzyme A + H+ ,
3.1.2.27: choloyl-CoA + H2O → cholate + coenzyme A + H+ ,
3.1.2.-: oleoyl-CoA + H2O → oleate + coenzyme A + H+ ,
3.1.2.-: 3-trans,5-cis-tetradecadienoyl-CoA + H2O → (3E,5Z)-tetradecadienoate + coenzyme A + H+ ,
3.1.3.1: a phosphate monoester + H2O → an alcohol + phosphate ,
3.1.3.2: a phosphate monoester + H2O → an alcohol + phosphate ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.4: a 1,2-diacyl-sn-glycerol 3-phosphate + H2O → a 1,2-diacyl-sn-glycerol + phosphate ,
3.1.3.5: AMP + H2O → adenosine + phosphate ,
3.1.3.5: β-nicotinamide D-ribonucleotide + H2O → 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
3.1.3.5: IMP + H2O → inosine + phosphate ,
3.1.3.5: UMP + H2O → uridine + phosphate ,
3.1.3.5: a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.5: GMP + H2O → guanosine + phosphate ,
3.1.3.5: XMP + H2O → xanthosine + phosphate ,
3.1.3.7: adenosine 3',5'-bisphosphate + H2O → AMP + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.13: 2,3-diphospho-D-glycerate + H2O → 3-phospho-D-glycerate + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.25: 1D-myo-inositol 4-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 2-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 3-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: a myo-inositol monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 6-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 5-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.27: an L-1-phosphatidylglycerol-phosphate + H2O → an L-1-phosphatidyl-glycerol + phosphate ,
3.1.3.29: N-acetyl-β-neuraminate 9-phosphate + H2O → N-acetyl-β-neuraminate + phosphate ,
3.1.3.29: an N-acyl-β-neuraminate 9-phosphate + H2O → an N-acyl-β-neuraminate + phosphate ,
3.1.3.36: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate ,
3.1.3.46: β-D-fructose 2,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.56: D-myo-inositol (1,3,4,5)-tetrakisphosphate + H2O → D-myo-inositol (1,3,4)-trisphosphate + phosphate ,
3.1.3.56: D-myo-inositol (1,4,5)-trisphosphate + H2O → D-myo-inositol (1,4)-bisphosphate + phosphate ,
3.1.3.57: D-myo-inositol (1,4)-bisphosphate + H2O → 1D-myo-inositol 4-monophosphate + phosphate ,
3.1.3.57: D-myo-inositol (1,3,4)-trisphosphate + H2O → D-myo-inositol (3,4)-bisphosphate + phosphate ,
3.1.3.58: D-glucopyranose 6-phosphate + H2O → D-glucopyranose + phosphate ,
3.1.3.58: β-D-glucose 6-phosphate + H2O → β-D-glucose + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,3,5,6) pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → a D myo-inositol penta kis phosphate + phosphate ,
3.1.3.62: D-myo-inositol (1,3,4,5)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate ,
3.1.3.62/3.1.3.72: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → 1D-myo-inositol (1,2,3,4,6)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,3,4,5)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,4,5,6)-pentakisphosphate + phosphate ,
3.1.3.64: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.66: D-myo-inositol (3,4)-bisphosphate + H2O → 1D-myo-inositol 3-monophosphate + phosphate ,
3.1.3.66: D-myo-inositol (1,3,4)-trisphosphate + H2O → D-myo-inositol (1,3)-bisphosphate + phosphate ,
3.1.3.66: a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate ,
3.1.3.67: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + phosphate ,
3.1.3.67: a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate ,
3.1.3.74: pyridoxal 5'-phosphate + H2O → pyridoxal + phosphate ,
3.1.3.74: pyridoxamine 5'-phosphate + H2O → pyridoxamine + phosphate ,
3.1.3.75: phosphoryl-ethanolamine + H2O → ethanolamine + phosphate ,
3.1.3.75: phosphocholine + H2O → choline + phosphate ,
3.1.3.77: 5-(methylthio)-2,3-dioxopentyl 1-phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate + H+ ,
3.1.3.78: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate ,
3.1.3.80: 2,3-diphospho-D-glycerate + H2O → 2-phospho-D-glycerate + phosphate ,
3.1.3.84: ADP ribose 1''-phosphate + H2O → ADP-D-ribose + phosphate ,
3.1.3.86: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate ,
3.1.3.87: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl 1-phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate ,
3.1.3.91: CMP + H2O → cytidine + phosphate ,
3.1.3.95: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate ,
3.1.3.-: D-myo-inositol (1,4,5,6)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate ,
3.1.3.-: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (1,4,5,6)-tetrakisphosphate + phosphate ,
3.1.3.-: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.-: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate ,
3.1.3.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (3,4,5,6)-tetrakisphosphate + phosphate ,
3.1.4.1: an oligonucleotide + H2O → an oligonucleotide + a nucleoside 5'-monophosphate ,
3.1.4.3: a phosphatidylcholine + H2O → phosphocholine + a 1,2-diacyl-sn-glycerol + H+ ,
3.1.4.4: a phosphatidylcholine + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + choline + H+ ,
3.1.4.11: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1,2-diacyl-sn-glycerol + D-myo-inositol (1,4,5)-trisphosphate + H+ ,
3.1.4.11: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → a 1,2-diacyl-sn-glycerol + D-myo-inositol (1,4)-bisphosphate + H+ ,
3.1.4.12: a sphingomyelin + H2O → a ceramide + phosphocholine + H+ ,
3.1.4.17: a cyclic 3',5'-nucleoside monophosphate + H2O → a nucleoside 5'-monophosphate + H+ ,
3.1.4.35: cyclic-GMP + H2O → GMP + H+ ,
3.1.4.37: guanosine 2',3'-cyclic monophosphate + H2O → guanosine 2'-monophosphate + H+ ,
3.1.4.37: adenosine 2',3'-cyclic monophosphate + H2O → adenosine 2'-monophosphate + H+ ,
3.1.4.37: uridine 2'3'-cyclic monophosphate + H2O → uridine 2'-monophosphate + H+ ,
3.1.4.37: a 2',3'-cyclic nucleoside phosphate + H2O → a nucleoside 2'-phosphate + H+ ,
3.1.4.37: cytidine 2',3'-cyclic monophosphate + H2O → cytidine 2'-monophosphate + H+ ,
3.1.4.44: sn-glycero-3-phospho-1-inositol + H2O → myo-inositol + sn-glycerol 3-phosphate + H+ ,
3.1.4.45: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O → glycoprotein-phospho-D-mannose + N-acetyl-β-D-glucosamine + H+ ,
3.1.4.46: a glycerophosphodiester + H2O → an alcohol + sn-glycerol 3-phosphate + H+ ,
3.1.4.50: 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + 1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + H+ ,
3.1.4.54: an N-acylphosphatidylethanolamine + H2O → an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ ,
3.1.4.-: ADP ribose 1'',2''-cyclic phosphate + H2O → ADP ribose 1''-phosphate + H+ ,
3.1.6.1: a phenol sulfate + H2O → a phenol + sulfate + H+ ,
3.1.6.2: 3-β-hydroxyandrost-5-en-17-one 3-sulfate + H2O → sulfate + dehydroepiandrosterone + 3 H+ ,
3.1.6.4: [keratan]-galactose 6'-sulfate + H2O → [keratan]-galactose + sulfate + H+ ,
3.1.6.4: [chondroitin]-6-O-sulfo-N-acetylgalactosamine + H2O → [chondroitin]-N-acetyl-galactosamine + sulfate + H+ ,
3.1.6.8: a cerebroside 3-sulfate + H2O → a cerebroside + sulfate + H+ ,
3.1.6.12: [chondroitin]-4-O-sulfo-N-acetylgalactosamine + H2O → [chondroitin]-N-acetyl-galactosamine + sulfate + H+ ,
3.1.6.13: [dermatan-sulfate]-2-O-sulfo-α-L-iduronate + H2O → [dermatan]-α-L-iduronate + sulfate + 2 H+ ,
3.1.6.13: [heparan-sulfate]-2-O-sulfo-α-L-iduronate + H2O → [heparan-sulfate]-α-L-iduronate + sulfate + H+ ,
3.1.6.14: [heparan sulfate]-α-N-acetyl-D-glucosamine 6-O-sulfate + H2O → [heparan sulfate]-N-acetyl-α-D-glucosamine + sulfate + H+ ,
3.1.6.14: [keratan sulfate]-α-N-acetyl-D-glucosamine 6-O-sulfate + H2O → [keratan sulfate]-α-N-acetyl-D-glucosamine + sulfate + H+ ,
3.1.6.18: [heparan-sulfate]-2-O-sulfo-β-D-glucuronate + H2O → [heparan-sulfate]-β-D-glucuronate + sulfate + H+ ,
3.1.6.18: [chondroitin-sulfate]-2-O-sulfo-β-D-glucuronate + H2O → [chondroitin-sulfate]-β-D-glucuronate + sulfate + 2 H+ ,
3.1.8.1: paraoxon + H2O → diethylphosphate + 4-nitrophenol + 2 H+ ,
3.1.8.1: an aryl dialkyl phosphate + H2O → a dialkyl phosphate + a phenol ,
3.1.8.1: amino-parathion + H2O → diethylthiophosphate + 4-aminophenol + H+ ,
3.1.8.1: methyl parathion + H2O → 4-nitrophenol + dimethylthiophosphate + 2 H+ ,
3.1.8.1: parathion + H2O → diethylthiophosphate + 4-nitrophenol + 2 H+ ,
3.1.11.1: DNAn + H2O → (deoxynucleotides)(n-1) + a 2'-deoxyribonucleoside 5'-monophosphate ,
3.1.11.-: DNAn + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.1: RNase II degradation substrate mRNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.3: an oligonucleotide + H2O → n a nucleoside 5'-monophosphate ,
3.1.13.4: a mRNA with poly(A) tail + n H2O → an mRNA + n AMP ,
3.1.21.1: a double stranded DNA + 2n H2O → n a 5'-phosphooligonucleotide + n a 5' phosphodinucleotide ,
3.1.22.1: a double stranded DNA + H2O → a 3' phosphooligonucleotide + a 5'-hydroxyoligonucleotide ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.11: a tRNA precursor + H2O → mature tRNA + a single-stranded oligoribonucleotide ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.27.1: RNA + H2O → a nucleoside 3'-phosphate + a 3' phosphooligonucleotide ,
3.1.27.5: RNA + H2O → a nucleoside 3'-phosphate + a 3' phosphooligonucleotide ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → n a 1,4-α-D-glucan ,
3.2.1.1: starch + n H2O → a large-branched glucan ,
3.2.1.1: starch + H2O → maltose + glucose ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → a 1,4-α-D-glucan + maltohexaose ,
3.2.1.3: a debranched limit dextrin + n H2O → n β-D-glucose ,
3.2.1.3: {6-α-D-(1,4-α-D-glucano)-glucan}n + H2O → {6-α-D-(1,4-α-D-glucano)-glucan}n-1 + β-D-glucose ,
3.2.1.10: β-isomaltose + H2O → α-D-glucose + D-glucopyranose ,
3.2.1.14: chitin + n H2O → n a chitodextrin ,
3.2.1.17: a peptidoglycan + H2O → a N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol + N-acetyl-D-glucosamine ,
3.2.1.18: a sialyloligosaccharide + H2O → an oligosaccharide + N-acetylneuraminate ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.20: α-maltose + H2O → 2 α-D-glucose ,
3.2.1.20: (1,4-α-D-glucosyl)(n) + H2O → (1,4-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.21: a β-D glucoside + H2O → a non glucosylated glucose acceptor + β-D-glucose ,
3.2.1.21: linamarin + H2O → acetone cyanohydrin + β-D-glucose ,
3.2.1.22: an α-D-galactoside + H2O → α-D-galactose + a non galactosylated galactose acceptor ,
3.2.1.22: melibiose + H2O → α-D-galactose + β-D-glucose ,
3.2.1.22: stachyose + H2O → raffinose + α-D-galactose ,
3.2.1.23: XXLG xyloglucan oligosaccharide + H2O → XXXG xyloglucan oligosaccharide + β-D-galactose ,
3.2.1.23: a β-D-galactoside + H2O → a non galactosylated galactose acceptor + β-D-galactose ,
3.2.1.23: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.23: XLLG xyloglucan oligosaccharide + 2 H2O → XXXG xyloglucan oligosaccharide + 2 β-D-galactose ,
3.2.1.23: 3'-ketolactose + H2O → 3-keto-β-D-galactose + β-D-glucose ,
3.2.1.23: XLXG xyloglucan oligosaccharide + H2O → XXXG xyloglucan oligosaccharide + β-D-galactose ,
3.2.1.24: an α-D-mannoside + H2O → α-D-mannose + a non glycosylated sugar acceptor ,
3.2.1.25: a β-D-mannoside + H2O → β-D-mannose + a non glycosylated sugar acceptor ,
3.2.1.28: α,α-trehalose + H2O → β-D-glucose + α-D-glucose ,
3.2.1.31: a β-D-glucuronoside + H2O → D-glucopyranuronate + an alcohol ,
3.2.1.33: a limit dextrin + H2O → maltotetraose + a debranched limit dextrin ,
3.2.1.33: a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose ,
3.2.1.35: dermatan sulfate + n H2O → n dermatan sulfate disaccharide ,
3.2.1.35: hyaluronan + n H2O → n hyaluronate ,
3.2.1.35: chondroitin sulfate + n H2O → n chondroitin sulfate disaccharide ,
3.2.1.37: a (1->4)-β-D-xylan oligosaccharide + n H2O → n β-D-xylopyranose ,
3.2.1.44: a fucoidan + H2O → fucose + a fucose sulfate + an oligosaccharide ,
3.2.1.45: a D-glucosyl-N-acylsphingosine + H2O → an N-acylsphingosine + β-D-glucose ,
3.2.1.46: a D-galactosyl-N-acylsphingosine + H2O → an N-acylsphingosine + β-D-galactose ,
3.2.1.48: sucrose + H2O → β-D-fructofuranose + α-D-glucose ,
3.2.1.49: N-acetyl-α-D-glucosaminyl-[glycoprotein] + H2O → N-acetyl-α-D-galactosamine + a glycoprotein ,
3.2.1.50: an N-acetyl-α-D-glucosaminide + H2O → N-acetyl-α-D-glucosamine + a non glycosylated sugar acceptor ,
3.2.1.51: α-L-fucoside + H2O → L-fucopyranose + an alcohol ,
3.2.1.52: chitotriose + H2O → N,N'-diacetylchitobiose + N-acetyl-D-glucosamine ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.1.52: N,N'-diacetylchitobiose + H2O → 2 N-acetyl-D-glucosamine ,
3.2.1.52: an N-acetyl-β-D-galactosalaminyl-[glycan] + H2O → a glycan + N-acetyl-β-D-galactosamine ,
3.2.1.52: an N-acetyl-β-D-hexosaminide + H2O → an N-acetyl-β-D-hexosamine + an alcohol ,
3.2.1.62: glycosyl-N-acylsphingosine + H2O → a ceramide + a sugar ,
3.2.1.76: [dermatan]-α-L-iduronate + H2O → α-L-iduronate + [dermatan]-N-acetyl-D-galactosamine ,
3.2.1.84: (1,3-α-D-glucosyl)(n) + H2O → (1,3-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.96: a glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine + H2O → N-acetyl-D-glucosamine-asparagine + a glycopeptide-D-mannosyl-N4-N-acetyl-D-glucosamine ,
3.2.1.106: Glc3Man9GlcNAc2 + H2O → Glc2Man9GlcNAc2 + D-glucopyranose ,
3.2.1.108: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.113: a (mannosyl)9-(N-acetylglucosaminyl)2 + H2O → a (mannosyl)8-(N-acetylglucosaminyl)2 + D-mannose ,
3.2.1.114: a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan + 2 H2O → N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine + 2 α-D-mannose ,
3.2.1.127: an immunoglobulin G glycopeptide + H2O → fragments of immunoglobuline G glycopeptide + α-L-fucopyranose ,
3.2.1.130: a GlcMan9(GlcNAc)2-glycoprotein + H2O → a GlcMan8(GlcNAc)2-glycoprotein + D-glucosyl-α(1→3)- mannose ,
3.2.1.143: poly(ADP-D-ribose)(n) + H2O → poly(ADP-D-ribose)(n-1) + ADP-D-ribose ,
3.2.1.166: heparan sulfate containing a glucuronate--N,3-O-disulfo-D-glucosamine disaccharide + n H2O → n short heparan sulfate fragments ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-L-threonine-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [protein]-L-threonine ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-L-serine-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [protein]-L-serine ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) ,
3.2.1.170: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate + H2O → α-D-mannose 6-phosphate + D-glycerate ,
3.2.1.183: UDP-N-acetyl-α-D-glucosamine + H2O → N-acetyl-α-D-mannosamine + UDP + H+ ,
3.2.1.-: a long-linear glucan + n H2O → a linear malto-oligosaccharide ,
3.2.2.6: NAD+ + H2O → ADP-D-ribose + nicotinamide + H+ ,
3.2.2.19: Nω-(ADP-D-ribosyl)-L-arginine + H2O → ADP-D-ribose + L-arginine ,
3.2.2.19: a protein-Nω-(ADP-D-ribosyl)-L-arginine + H2O → ADP-D-ribose + a [protein]-L-arginine ,
3.2.2.21: an alkylated DNA + H2O → DNAn + an alkylated nucleobase ,
3.2.2.29: a DNA containing a mismatch + H2O → a DNA containing an apyrimidinic site + thymine ,
3.3.1.1: S-adenosyl-L-homocysteine + H2O → L-homocysteine + adenosine ,
3.3.2.6: leukotriene A4 + H2O → leukotriene B4 ,
3.3.2.9: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol ,
3.3.2.10: an epoxide + H2O = a glycol ,
3.3.2.-: 4(5)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D4 ,
3.3.2.-: 7S-hydroperoxy,17R-H-docosahexaenoate → 7(8)-epoxy-17R-H-docosahexaenoate + H2O ,
3.3.2.-: 7(8)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D2 ,
3.3.2.-: 4S-hydroperoxy,17S-H-docosahexaenoate → 4(5)-epoxy-17S-H-docosahexaenoate + H2O ,
3.3.2.-: 4S-hydroperoxy,17R-H-docosahexaenoate → 4(5)-epoxy-17R-H-docosahexaenoate + H2O ,
3.3.2.-: 7(8)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D1 ,
3.3.2.-: 4(5)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D3 ,
3.3.2.-: 7S-hydroperoxy,17S-H-docosahexaenoate → 7(8)-epoxy-17S-H-docosahexaenoate + H2O ,
3.3.2.-: 4(5)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D3 ,
3.3.2.-: 7(8)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D2 ,
3.3.2.-: 4(5)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D4 ,
3.3.2.-: 7(8)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D1 ,
3.4.11.2: 4-hydroxy-2-nonenal-[Cys-Gly] conjugate + H2O → 4-hydroxy-2-nonenal-[L-Cys] conjugate + glycine ,
3.4.11.2: a polypeptide + H2O → a polypeptide + an L-amino acid ,
3.4.11.2: a [Cys-Gly]-S-conjugate + H2O → an L-cysteine-S-conjugate + glycine ,
3.4.11.3: a protein + H2O → a peptide + a peptide ,
3.4.11.5: an N-terminal [protein]-L-proline + H2O → a peptide + L-proline ,
3.4.11.6: a protein + H2O → a peptide + a peptide ,
3.4.11.7: a [protein] N-terminal L-glutamate + H2O → L-glutamate + a protein + H+ ,
3.4.11.9: a peptide + H2O → a standard α amino acid + a peptide ,
3.4.11.14: amino acids(n) + H2O → amino acids(n-1) + a standard α amino acid ,
3.4.11.18: a peptide with N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.11.21: a protein + H2O → a peptide + a peptide ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.13.18: L-alanyl-L-histidine + H2O → L-alanine + L-histidine ,
3.4.13.18: a dipeptide + H2O → 2 a standard α amino acid ,
3.4.13.18: L-cysteinyl-glycine + H2O → L-cysteine + glycine ,
3.4.13.18: L-alanyl-L-aspartate + H2O → L-alanine + L-aspartate ,
3.4.13.19: a dipeptide + H2O → 2 amino acids ,
3.4.13.19: leukotriene-D4 + H2O → glycine + leukotriene-E4 ,
3.4.13.20: a dipetide with L-histidine at the C-terminal + H2O → a standard α amino acid + L-histidine ,
3.4.13.21: a dipetide with L-aspartate at the N-terminal + H2O → L-aspartate + a standard α amino acid ,
3.4.14.1: a peptide + n H2O → n+1 a dipeptide ,
3.4.14.2: an oligopeptide + H2O → a dipeptide + a peptide ,
3.4.14.4: an oligopeptide + H2O → a peptide + a dipeptide ,
3.4.14.5: a polypeptide + H2O → a dipeptide + a peptide ,
3.4.14.9: a polypeptide + H2O → a peptide + a tripeptide ,
3.4.14.10: a polypeptide + H2O → a peptide + a tripeptide ,
3.4.15.1: an oligopeptide + H2O → a dipeptide + a peptide ,
3.4.16.2: an oligopeptide + H2O → a peptide + a standard α amino acid ,
3.4.16.5: a peptide + H2O → a peptide + a standard α amino acid ,
3.4.16.6: a protein + H2O → a basic amino acid + a protein ,
3.4.17.11: folate + H2O → pteroate + a glutamate ,
3.4.17.12: a protein + H2O → a protein + an α amino acid ,
3.4.17.15: a peptide + H2O → a peptide + an aromatic amino acid ,
3.4.17.20: a peptide + H2O → a peptide + a basic amino acid ,
3.4.17.21: a peptide + H2O → a peptide + L-glutamate ,
3.4.17.22: a peptide + H2O → a basic amino acid + a peptide ,
3.4.18.1: a protein + H2O → a peptide + a peptide ,
3.4.19.5: a protein + H2O → a protein + L-aspartate ,
3.4.19.6: a 5-oxoprolyl-peptide + H2O → 5-oxoproline + a peptide ,
3.4.19.9: tetrahydropteroyl-[γ-Glu](n) + H2O → tetrahydropteroyl-[γ-Glu](n-1) + L-glutamate ,
3.4.19.9: a glutathione-toxin conjugate + H2O → a [Cys-Gly]-S-conjugate + L-glutamate ,
3.4.19.9: 4-hydroxy-2-nonenal-glutathione conjugate + H2O → 4-hydroxy-2-nonenal-[Cys-Gly] conjugate + L-glutamate ,
3.4.19.12: a ubiquitin C-terminal thioester + H2O → a ubiquitin + a thiol ,
3.4.19.13: glutathione + H2O → L-cysteinyl-glycine + L-glutamate ,
3.4.21.1: a protein + H2O → a peptide + a peptide ,
3.4.21.2: a protein + H2O → a peptide + a peptide ,
3.4.21.4: a protein + H2O → a peptide + a peptide ,
3.4.21.5: a fibrinogen + H2O → a fibrin + a fibrinopeptide A + a fibrinopeptide B ,
3.4.21.6: a prothrombin + H2O → a thrombin + a peptide + a peptide ,
3.4.21.7: a fibrin + H2O → n a peptide ,
3.4.21.9: trypsinogen + H2O → trypsin + a peptide ,
3.4.21.10: a protein + H2O → a peptide + a peptide ,
3.4.21.20: a protein + H2O → a peptide + a peptide ,
3.4.21.21: a factor X + H2O → a factor Xa + a factor Xa ,
3.4.21.22: a factor X + H2O → a factor Xa + a factor Xa ,
3.4.21.26: a protein + H2O → a peptide + a peptide ,
3.4.21.27: a factor IX + H2O → a factor IXa + a factor IXa ,
3.4.21.34: a protein + H2O → a peptide + a peptide ,
3.4.21.35: a protein + H2O → a peptide + a peptide ,
3.4.21.36: a protein + H2O → a peptide + a peptide ,
3.4.21.37: a protein + H2O → a peptide + a peptide ,
3.4.21.38: a factor VII + H2O → a factor VIIa + a factor VIIa ,
3.4.21.38: a factor XI + H2O → a factor XIa ,
3.4.21.39: a protein + H2O → a peptide + a peptide ,
3.4.21.41: complement subcomponent C1s + H2O → activated complement subcomponent C1s ,
3.4.21.43/3.4.21.47: a complement 5 α chain + H2O → a C5a anaphylatoxin + a complement C5 α' chain ,
3.4.21.45: complement component protein C3b + H2O → complement component protein C3c + complement component protein C3d ,
3.4.21.45: complement component protein C4b + H2O → complement component protein C4c + complement component protein C4d ,
3.4.21.46: complement factor B + H2O → complement factor Ba + complement factor Bb ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.59: a protein + H2O → a peptide + a peptide ,
3.4.21.68: a plasminogen + H2O → a plasmin ,
3.4.21.69: a factor Va + H2O → n a peptide ,
3.4.21.69: a factor VIIIa + H2O → n a peptide ,
3.4.21.70: a protein + H2O → a peptide + a peptide ,
3.4.21.71: a protein + H2O → a peptide + a peptide ,
3.4.21.73: a plasminogen + H2O → a plasmin ,
3.4.21.75: a protein precursor + H2O → a mature protein ,
3.4.21.76: a protein + H2O → a peptide + a peptide ,
3.4.21.77: semenogelin-1 + H2O → n fragments of semenogelin-1 ,
3.4.21.78: a protein + H2O → a peptide + a peptide ,
3.4.21.79: a protein + H2O → a peptide + a peptide ,
3.4.21.83: an oligopeptide + H2O → a peptide + a peptide ,
3.4.21.89: a peptide with a leader sequence + H2O → a peptide + a leader sequence ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.93: a protein + H2O → a peptide + a peptide ,
3.4.21.94: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a cleaved lipoprotein signal peptide + H2O → n a peptide ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.22.1: a protein + H2O → a peptide + a peptide ,
3.4.22.15: a protein + H2O → a peptide + a peptide ,
3.4.22.16: a protein + H2O → a peptide + a peptide ,
3.4.22.27: a protein + H2O → a peptide + a peptide ,
3.4.22.34: a protein + H2O → a peptide + a peptide ,
3.4.22.36: pro-interleukin-1β + H2O → mature pro-interleukin-1β ,
3.4.22.38: a protein + H2O → a peptide + a peptide ,
3.4.22.40: a bleomycin + H2O → a deamido-bleomycin ,
3.4.22.41: a protein + H2O → a peptide + a peptide ,
3.4.22.42: a protein + H2O → a peptide + a peptide ,
3.4.22.43: a protein + H2O → a peptide + a peptide ,
3.4.23.1: a protein + H2O → a peptide + a peptide ,
3.4.23.3: a protein + H2O → a peptide + a peptide ,
3.4.23.5: a protein + H2O → a peptide + a peptide ,
3.4.23.15: an angiotensinogen + H2O → angiotensin I + a cleaved angiotensinogen ,
3.4.23.34: a protein + H2O → a peptide + a peptide ,
3.4.23.49: a protein + H2O → a peptide + a peptide ,
3.4.24.3: a collagen + H2O → n a peptide ,
3.4.24.7: a collagen + H2O → a peptide + a peptide ,
3.4.24.11: a protein + H2O → a peptide + a peptide ,
3.4.24.14: a procollagen + H2O → a cleaved procollagen + a peptide ,
3.4.24.15: a protein + H2O → a peptide + a peptide ,
3.4.24.16: an oligopeptide + H2O → a peptide + a peptide ,
3.4.24.17: a protein + H2O → a peptide + a peptide ,
3.4.24.18: a protein + H2O → a peptide + a peptide ,
3.4.24.19: a procollagen + H2O → C-terminal propeptides of procollagen + a peptide ,
3.4.24.22: a protein + H2O → a peptide + a peptide ,
3.4.24.23: a protein + H2O → a peptide + a peptide ,
3.4.24.24: a protein + H2O → a peptide + a peptide ,
3.4.24.34: a protein + H2O → a peptide + a peptide ,
3.4.24.35: a protein + H2O → a peptide + a peptide ,
3.4.24.55: a protein + H2O → n a peptide ,
3.4.24.56: a polypeptide + H2O → n a peptide ,
3.4.24.57: a O-sialoglycoprotein + H2O → n a peptide ,
3.4.24.59: mitochondrial intermediate protein + H2O → an octapeptide + a mature protein ,
3.4.24.61: a protein + H2O → a peptide + a peptide ,
3.4.24.64: a mitochondrial preprotein including a mitochondrial targeting sequence + H2O → a processed mitochondrial protein + a peptide ,
3.4.24.65: a protein + H2O → n a peptide ,
3.4.24.71: big endothelin + H2O → endothelin 1 + a peptide ,
3.4.24.81: a protein + H2O → 2 a peptide ,
3.4.24.82: aggrecan + H2O → n an aggrecan cleavage product ,
3.4.24.84: a protein S-farnesyl-L-cysteine + H2O → a [protein] c-terminal S-farnesyl-L-cysteine + a peptide ,
3.5.1.6: 3-ureido-isobutyrate + H2O + 2 H+ → (R)-3-amino-2-methylpropanoate + ammonium + CO2 ,
3.5.1.6: 3-ureidopropionate + H2O + 2 H+ → β-alanine + ammonium + CO2 ,
3.5.1.9: N-formylkynurenine + H2O → L-kynurenine + formate + H+ ,
3.5.1.10: an N10-formyl-tetrahydrofolate + H2O → a tetrahydrofolate + formate + H+ ,
3.5.1.12: biotin amide + H2O = ammonium + biotin ,
3.5.1.14: an N-acylated aliphatic-L-amino acid + H2O = a carboxylate + an aliphatic L-amino acid ,
3.5.1.15: an N-acyl-L-aspartate + H2O → L-aspartate + a carboxylate ,
3.5.1.15: N-acetyl-L-aspartate + H2O = L-aspartate + acetate ,
3.5.1.23: an α hydroxyphytoceramide + H2O ↔ phytosphingosine + a hydroxy fatty acid ,
3.5.1.23: a ceramide + H2O = a sphingoid base + a fatty acid ,
3.5.1.23: an N-acylsphingosine + H2O → sphingosine + a fatty acid ,
3.5.1.25: N-acetyl-D-galactosamine 6-phosphate + H2O = acetate + D-galactosamine 6-phosphate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.26: N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O → N-acetyl-β-glucosaminylamine + L-aspartate + H+ ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O = N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala ,
3.5.1.38: L-asparagine + H2O → L-aspartate + ammonium ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.52: a [protein]-N4-(N-acetyl-β-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-β-glucosaminylamine + a [protein]-L-aspartate + H+ ,
3.5.1.63: 4-acetamidobutanoate + H2O → 4-aminobutanoate + acetate ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O = a [protein] N-terminal L-methionine + formate ,
3.5.1.89: a 6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O = 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate ,
3.5.1.92: pantetheine + H2O = (R)-pantothenate + cysteamine ,
3.5.1.99: oleamide + H2O = oleate + ammonium ,
3.5.1.99: anandamide + H2O → arachidonate + ethanolamine ,
3.5.1.109: an N-acyl-sphingosylphosphorylcholine + H2O → a fatty acid + sphingosylphosphorylcholine ,
3.5.1.109: a D-glucosyl-N-acylsphingosine + H2O = a fatty acid + D-glucosyl-sphingosine ,
3.5.1.111: 2-oxoglutaramate + H2O → 2-oxoglutarate + ammonium ,
3.5.2.2: 5,6-dihydrouracil + H2O → 3-ureidopropionate + H+ ,
3.5.2.2: 5,6-dihydrothymine + H2O → 3-ureido-isobutyrate + H+ ,
3.5.2.2: hydantoin + H2O = N-carbamoylglycine + H+ ,
3.5.2.3: (S)-dihydroorotate + H2O ← N-carbamoyl-L-aspartate + H+ ,
3.5.2.7: 4-imidazolone-5-propionate + H2O → N-formimino-L-glutamate ,
3.5.2.9: 5-oxoproline + ATP + 2 H2O → L-glutamate + ADP + phosphate + H+ ,
3.5.3.1: L-arginine + H2O → urea + L-ornithine ,
3.5.3.4: allantoate + H2O = S-ureidoglycolate + urea ,
3.5.3.11: agmatine + H2O → urea + putrescine ,
3.5.3.18: N6,N6-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline ,
3.5.4.3: guanine + H+ + H2O → ammonium + xanthine ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.5: cytidine + H+ + H2O → uridine + ammonium ,
3.5.4.5: 2'-deoxycytidine + H+ + H2O → 2'-deoxyuridine + ammonium ,
3.5.4.9: a 5,10-methenyltetrahydrofolate + H2O ↔ an N10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ← 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.12: dCMP + H+ + H2O → ammonium + dUMP ,
3.5.4.16: GTP + H2O → formate + 7,8-dihydroneopterin 3'-triphosphate + H+ ,
3.5.4.17: AMP + H+ + H2O → IMP + ammonium ,
3.5.5.1: a nitrile + 2 H2O = a carboxylate + ammonium ,
3.5.5.1: indole-3-acetonitrile + 2 H2O = ammonium + indole-3-acetate ,
3.5.99.6: α-D-glucosamine 6-phosphate + H2O ↔ β-D-fructofuranose 6-phosphate + ammonium ,
3.5.99.10: 2-iminopropanoate + H+ + H2O → pyruvate + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.5: UTP + 2 H2O → UMP + 2 phosphate + 2 H+ ,
3.6.1.5: ATP + 2 H2O → AMP + 2 phosphate + 2 H+ ,
3.6.1.5: a nucleoside triphosphate + 2 H2O → a nucleoside 5'-monophosphate + 2 phosphate + 2 H+ ,
3.6.1.5: CTP + 2 H2O → CMP + 2 phosphate + 2 H+ ,
3.6.1.5: ADP + H2O = AMP + phosphate + H+ ,
3.6.1.6: CDP + H2O → CMP + phosphate + H+ ,
3.6.1.6: a nucleoside diphosphate + H2O = a nucleoside 5'-monophosphate + phosphate + H+ ,
3.6.1.6: UDP + H2O → UMP + phosphate + H+ ,
3.6.1.6: dCDP + H2O → dCMP + phosphate + H+ ,
3.6.1.7: an acyl phosphate + H2O = a carboxylate + phosphate + H+ ,
3.6.1.9: a dinucleotide (nucleic acid) + H2O = 2 a nucleoside 5'-monophosphate + 2 H+ ,
3.6.1.9: NADH + H2O = NMNH + AMP + 2 H+ ,
3.6.1.14: adenosine pentaphosphate + H2O = adenosine tetraphosphate + phosphate + H+ ,
3.6.1.14: adenosine tetraphosphate + H2O = ATP + phosphate + 2 H+ ,
3.6.1.15: UTP + H2O → UDP + phosphate + H+ ,
3.6.1.15: a nucleoside triphosphate + H2O → a nucleoside diphosphate + phosphate + H+ ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.16: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+ ,
3.6.1.17: P1,P4-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP + 2 H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.19: ITP + H2O = IMP + diphosphate + H+ ,
3.6.1.19: dGTP + H2O → dGMP + diphosphate + H+ ,
3.6.1.19: a nucleoside triphosphate + H2O → a nucleoside 5'-monophosphate + diphosphate + H+ ,
3.6.1.21: an ADP-sugar + H2O = AMP + an α-D-aldose 1-phosphate ,
3.6.1.28: thiamin triphosphate + H2O = thiamin diphosphate + phosphate + H+ ,
3.6.1.29: 5',5'''-diadenosine triphosphate + H2O = AMP + ADP + 2 H+ ,
3.6.1.43: dolichyl diphosphate + H2O = a dolichyl phosphate + phosphate + H+ ,
3.6.1.45: a UDP-sugar + H2O → UMP + an α-D-aldose 1-phosphate + 2 H+ ,
3.6.1.52: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: a diphospho-1D-myo-inositol tetrakisphosphate + H2O = D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: a pyrophosphate-containing inositol phosphate + H2O = a myo-inositol-polyphosphate + phosphate ,
3.6.1.52: 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + H2O = 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate + H+ ,
3.6.1.53: ADP-D-ribose + H2O = AMP + D-ribofuranose 5-phosphate + 2 H+ ,
3.6.1.53: CDP-choline + H2O = CMP + phosphocholine + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.56: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate + H+ ,
3.6.1.58: 8-oxo-dGDP + H2O → 8-oxo-dGMP + phosphate + H+ ,
3.6.1.60: 5',5'''-diadenosine pentaphosphate + H2O = adenosine tetraphosphate + AMP + H+ ,
3.6.1.60: 5',5'''-diadenosine hexaphosphate + H2O = adenosine pentaphosphate + AMP + H+ ,
3.6.1.65: dCTP + H2O = dCMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GDP + H2O → 8-oxo-GMP + phosphate + H+ ,
3.6.1.-: 8-oxo-dADP + H2O → 8-oxo-dAMP + phosphate + H+ ,
3.6.3.1: a phospholipid[out] + ATP + H2O → a phospholipid[cytosol] + ADP + phosphate + H+ ,
3.6.3.4: Cu2+[cytosol] + ATP + H2O ↔ Cu2+[golgi lumen] + ADP + phosphate + 2 H+ ,
3.6.3.4: Cu2+[cytosol] + ATP + H2O → Cu2+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[endoplasmic reticulum lumen] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[golgi lumen] + ADP + phosphate + H+ ,
3.6.3.9: 2 K+[extracellular space] + 3 Na+[cytosol] + ATP + H2O → 2 K+[cytosol] + 3 Na+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.10: K+[extracellular space] + ATP + H+[cytosol] + H2O → ADP + K+[cytosol] + phosphate + H+[cytosol] + H+[cytosol] ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.44: a xenobiotic[cytosol] + ATP + H2O ↔ a xenobiotic[extracellular space] + ADP + phosphate ,
3.6.3.49: chloride[out] + ATP + H2O ↔ chloride[cytosol] + ADP + phosphate + H+ ,
3.6.3.-: Cu2+[out] + ATP + H2O ↔ Cu2+[in] + ADP + phosphate + H+ ,
3.6.3.-: Ca2+[in] + ATP + H2O ↔ Ca2+[out] + ADP + phosphate + H+ ,
3.6.4.3: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.4: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.6: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.7: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.12: a double-helix DNA + ATP + H2O → an unwound double-stranded DNA + ADP + phosphate + H+ ,
3.6.4.13: ATP + H2O = ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
3.7.1.2: 4-fumaryl-acetoacetate + H2O → fumarate + acetoacetate + H+ ,
3.7.1.3: L-kynurenine + H2O → L-alanine + anthranilate + H+ ,
3.7.1.3: 3-hydroxy-L-kynurenine + H2O → 3-hydroxyanthranilate + L-alanine + H+ ,
3.10.1.1: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate ,
3.13.1.-: 3-sulfinopyruvate + H2O → sulfite + pyruvate + H+ ,
4.1.1.4: acetoacetate + H+ → acetone + CO2 ,
4.1.1.6: cis-aconitate + H+ = CO2 + itaconate ,
4.1.1.9: malonyl-CoA + H+ → CO2 + acetyl-CoA ,
4.1.1.15: L-glutamate + H+ → CO2 + 4-aminobutanoate ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.19: L-arginine + H+ → CO2 + agmatine ,
4.1.1.21: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ ← 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 ,
4.1.1.22: L-histidine + H+ = CO2 + histamine ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.25: L-tyrosine + H+ → CO2 + tyramine ,
4.1.1.28: L-dopa + H+ → dopamine + CO2 ,
4.1.1.28: L-tryptophan + H+ → CO2 + tryptamine ,
4.1.1.28: 5-hydroxy-L-tryptophan + H+ → serotonin + CO2 ,
4.1.1.29: 3-sulfinoalanine + H+ → CO2 + hypotaurine ,
4.1.1.32: oxaloacetate + ITP = CO2 + phosphoenolpyruvate + IDP ,
4.1.1.32: oxaloacetate + GTP → CO2 + phosphoenolpyruvate + GDP ,
4.1.1.33: (R)-mevalonate diphosphate + ATP → isopentenyl diphosphate + CO2 + ADP + phosphate ,
4.1.1.34: 3-keto-L-gulonate + H+ → L-xylulose + CO2 ,
4.1.1.35: UDP-α-D-glucuronate + H+ → UDP-α-D-xylose + CO2 ,
4.1.1.36: R-4'-phosphopantothenoyl-L-cysteine + H+ → 4'-phosphopantetheine + CO2 ,
4.1.1.37: uroporphyrinogen-I + 4 H+ = coproporphyrinogen I + 4 CO2 ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → 4 CO2 + coproporphyrinogen III ,
4.1.1.41: (S)-methylmalonyl-CoA + H+ = CO2 + propanoyl-CoA ,
4.1.1.45: aminocarboxymuconate semialdehyde + H+ → CO2 + 2-aminomuconate 6-semialdehyde ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.65: an L-1-phosphatidylserine + H+ = an L-1-phosphatidyl-ethanolamine + CO2 ,
4.1.1.70: (E)-glutaconyl-CoA + H+ ↔ CO2 + crotonyl-CoA ,
4.1.1.84: D-dopachrome + H+ = 5,6-dihydroxyindole + CO2 ,
4.1.1.90: a [protein] 4-carboxy-L-glutamate + vitamin K 2,3-epoxide + H2O = a [protein]-α-L-glutamate + CO2 + phylloquinone + oxygen + H+ ,
4.1.1.94: (S)-ethylmalonyl-CoA + H+ = butanoyl-CoA + CO2 ,
4.1.1.-: a 3-oxoacid + H+ → a methylketone + CO2 ,
4.1.1.-: 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate → acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.13: β-D-fructofuranose 1-phosphate → dihydroxyacetone phosphate + D-glyceraldehyde ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.27: sphinganine 1-phosphate = palmitaldehyde + phosphoryl-ethanolamine ,
4.1.2.30: 17-α-hydroxypregnenolone → dehydroepiandrosterone + acetaldehyde ,
4.1.3.3: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate ,
4.1.3.4: (S)-3-hydroxy-3-methylglutaryl-CoA → acetoacetate + acetyl-CoA ,
4.1.3.6: citrate = acetate + oxaloacetate ,
4.1.3.16: 4-hydroxy-2-oxoglutarate → glyoxylate + pyruvate ,
4.1.3.44: N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine → 4-demethylwyosine37 in tRNAPhe + L-methionine + 5'-deoxyadenosine + CO2 + H2O ,
4.1.99.14: (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA) = thymidylyl-(3'-5')-thymidylate (in DNA) ,
4.1.99.18: GTP → cyclic pyranopterin phosphate + diphosphate ,
4.1.-.-: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA → a 2-methyl branched 2,3,4-saturated fatty aldehyde + formyl-CoA ,
4.1.-.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA → an odd numbered straight chain 2,3,4-saturated fatty aldehyde + formyl-CoA ,
4.2.1.1: carbonic acid = CO2 + H2O ,
4.2.1.1: hydrogen carbonate + H+ = CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.17: OPC8-3-hydroxyacyl-CoA = OPC8-trans-2-enoyl-CoA + H2O ,
4.2.1.17: 2-methyl-3-hydroxybutyryl-CoA ← (E)-2-methylcrotonoyl-CoA + H2O ,
4.2.1.17: (S)-3-hydroxydecanoyl-CoA ← trans-Δ2-decenoyl-CoA + H2O ,
4.2.1.17: (S)-3-hydroxy-isobutanoyl-CoA ← methylacrylyl-CoA + H2O ,
4.2.1.17: OPC4-3-hydroxyacyl-CoA = OPC4-trans-2-enoyl-CoA + H2O ,
4.2.1.17: a (3S)-3-hydroxyacyl-CoA ← a trans-2-enoyl-CoA + H2O ,
4.2.1.17: a (3R)-3-hydroxyacyl-CoA = a cis-2-enoyl-CoA + H2O ,
4.2.1.17: OPC6-3-hydroxyacyl-CoA = OPC6-trans-2-enoyl-CoA + H2O ,
4.2.1.17: 3-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA = 4-coumaryl-CoA + H2O ,
4.2.1.17: 3-hydroxyadipyl-CoA = 2,3-didehydroadipyl-CoA + H2O ,
4.2.1.18: (S)-3-hydroxy-3-methylglutaryl-CoA ← 3-methylglutaconyl-CoA + H2O ,
4.2.1.22: L-homocysteine + L-serine → L-cystathionine + H2O ,
4.2.1.24: 2 5-aminolevulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.46: dTDP-α-D-glucose = dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O ,
4.2.1.47: GDP-α-D-mannose → GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.49: 4-imidazolone-5-propionate ← urocanate + H2O ,
4.2.1.55: (R)-3-hydroxybutanoyl-CoA = crotonyl-CoA + H2O ,
4.2.1.70: D-ribofuranose 5-phosphate + uracil = pseudouridine 5'-phosphate + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.77: trans-3-hydroxy-L-proline = Δ1-pyrroline-2-carboxylate + H2O + H+ ,
4.2.1.93: (S)-NADPHX + ATP = ADP + NADPH + phosphate + H+ ,
4.2.1.93: ATP + (S)-NADHX → ADP + NADH + phosphate + H+ ,
4.2.1.96: 4α-hydroxy-tetrahydrobiopterin → 7,8-dihydrobiopterin + H2O ,
4.2.1.107: (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + H2O → (24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA ,
4.2.1.107: (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA ← (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + H2O ,
4.2.1.109: 5-methylthioribulose 1-phosphate → 5-(methylthio)-2,3-dioxopentyl 1-phosphate + H2O ,
4.2.1.119: a (3R)-3-hydroxyacyl-CoA ↔ a trans-2-enoyl-CoA + H2O ,
4.2.1.134: a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H2O ,
4.2.1.150: (S)-3-hydroxybutanoyl-CoA ← crotonyl-CoA + H2O ,
4.2.1.-: benzyl-6-hydroxy-2-cyclohexene-on-oyl + H2O = 6-hydroxy-2-cyclohexen-one-carboxylate + benzyl alcohol + H+ ,
4.2.1.-: (3R)-3-hydroxy-stearoyl-CoA → trans-octadec-2-enoyl-CoA + H2O ,
4.2.3.12: 7,8-dihydroneopterin 3'-triphosphate → PPPi + 6-pyruvoyl tetrahydropterin + H+ ,
4.3.1.3: L-histidine → ammonium + urocanate ,
4.3.1.4: a 5-formiminotetrahydrofolate + 2 H+ → ammonium + a 5,10-methenyltetrahydrofolate ,
4.3.1.17: L-serine → pyruvate + ammonium ,
4.3.1.19: L-threonine → 2-oxobutanoate + ammonium ,
4.3.2.1: L-arginino-succinate ↔ L-arginine + fumarate ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.2.5: a C-terminal [protein]-hydroxyglycine = a peptidyl amide + glyoxylate ,
4.3.2.-: sphingosine 1-phosphate → 2-trans-hexadecenal + phosphoryl-ethanolamine ,
4.4.1.1: L-cystathionine + H2O → 2-oxobutanoate + L-cysteine + ammonium ,
4.4.1.5: (R)-S-lactoylglutathione ← methylglyoxal + glutathione ,
4.4.1.13: an L-cysteine-S-conjugate + H2O → pyruvate + a thiol + ammonium ,
4.4.1.16: L-selenocysteine + a reduced electron acceptor = L-alanine + selenide + an oxidized electron acceptor + 2 H+ ,
4.4.1.20: leukotriene-C4 ← leukotriene A4 + glutathione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.6.1.1: ATP = cyclic-AMP + diphosphate ,
4.6.1.2: GTP = cyclic-GMP + diphosphate ,
4.6.1.15: FAD = AMP + riboflavin cyclic-4',5'-phosphate ,
4.6.1.16: a polycistronic tRNA precursor → a tRNA intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus + a 3' half-tRNA molecule with a hydroxyl on its 5' end + a 5' half-tRNA molecule with a 2',3' cyclic phosphate on its 3' end ,
4.99.1.1: protoporphyrin IX + Fe2+ → ferroheme b + 2 H+ ,
5.1.1.18: L-serine = D-serine ,
5.1.2.3: a (3R)-3-hydroxyacyl-CoA → a (3S)-3-hydroxyacyl-CoA ,
5.1.3.1: D-ribulose 5-phosphate → D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.3: β-D-galactose → α-D-galactose ,
5.1.3.7: UDP-N-acetyl-α-D-glucosamine → UDP-N-acetyl-α-D-galactosamine ,
5.1.3.8: an N-acyl-D-glucosamine = an N-acyl-D-mannosamine ,
5.1.3.14: UDP-N-acetyl-α-D-glucosamine = UDP-N-acetyl-α-D-mannosamine ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.17: [heparan-sulfate]-β-D-glucuronate ↔ [heparan-sulfate]-α-L-iduronate ,
5.1.3.19: [chondroitin-sulfate]-β-D-glucuronate → [dermatan]-α-L-iduronate ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.1.99.1: (R)-methylmalonyl-CoA ← (S)-methylmalonyl-CoA ,
5.1.99.4: (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA ↔ (25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA ,
5.1.99.4: (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ↔ (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ,
5.1.99.4: a (2S)-2-methylacyl-CoA ↔ a (2R)-2-methylacyl-CoA ,
5.1.99.6: (R)-NADHX → (S)-NADHX ,
5.2.1.2: 4-maleyl-acetoacetate → 4-fumaryl-acetoacetate ,
5.2.1.8: peptidylproline (ω = 180) = peptidylproline (ω = 0) ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.6: D-ribose 5-phosphate ← D-ribulose 5-phosphate ,
5.3.1.8: α-D-mannose 6-phosphate ← β-D-fructofuranose 6-phosphate ,
5.3.1.9: D-glucopyranose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: α-D-glucose 6-phosphate = β-D-fructofuranose 6-phosphate ,
5.3.1.22: hydroxypyruvate = tartronate semialdehyde ,
5.3.1.23: S-methyl-5-thio-α-D-ribose 1-phosphate → 5-methylthioribulose 1-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.5: 5-(methylthio)-2,3-dioxopentyl 1-phosphate → 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl 1-phosphate + H+ ,
5.3.2.8: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate ↔ (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
5.3.3.1: a 3-oxo-δ5-steroid = a 3-oxo-Δ4-steroid ,
5.3.3.1: pregn-5-ene-3,20-dione → progesterone ,
5.3.3.1: campesterol = campest-4-en-3β-ol ,
5.3.3.1: cholest-5-en-3-one = cholest-4-en-3-one ,
5.3.3.1: 5-androstene-3,17-dione → androst-4-ene-3,17-dione ,
5.3.3.1: pregn-5-ene-3,20-dione-17-ol = 17-α-hydroxyprogesterone ,
5.3.3.1: 3-oxo-24-ethyl-cholest-5-ene = 3-oxo-24-ethyl-cholest-4-ene ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.5: lathosterol ← zymostenol ,
5.3.3.5: zymosterol → 5α-cholesta-7,24-dien-3β-ol ,
5.3.3.8: a trans-3-enoyl-CoA = a trans-2-enoyl-CoA ,
5.3.3.8: a trans2,cis-5-dienoyl-CoA = a trans3,cis-5-dienoyl-CoA ,
5.3.3.8: a cis-3-enoyl-CoA → a trans-2-enoyl-CoA ,
5.3.3.8: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA ,
5.3.3.12: L-dopachrome → 5,6-dihydroxyindole-2-carboxylate ,
5.3.3.-: a trans3,cis-5-dienoyl-CoA = a trans-2,trans-4-dienoyl-CoA ,
5.3.99.2: prostaglandin-H2 → prostaglandin D2 ,
5.3.99.3: prostaglandin-H2 → prostaglandin E2 ,
5.3.99.4: prostaglandin-H2 → prostaglandin I2 ,
5.3.99.5: prostaglandin-H2 → thromboxane A2 ,
5.4.1.-: α-lactose = allolactose ,
5.4.2.3: N-acetyl-α-D-glucosamine 1-phosphate ← N-acetyl-D-glucosamine 6-phosphate ,
5.4.2.4: 1,3-bisphospho-D-glycerate → 2,3-diphospho-D-glycerate + H+ ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.5: α-D-glucose 1-phosphate → D-glucopyranose 6-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate → D-ribose 5-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ← α-D-mannose 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.99.2: (R)-methylmalonyl-CoA → succinyl-CoA ,
5.4.99.7: (3S)-2,3-epoxy-2,3-dihydrosqualene = lanosterol ,
5.4.99.25: a tRNA uridine55 = a tRNA pseudouridine55 ,
5.4.99.26: a tRNA uridine65 = a tRNA pseudouridine65 ,
5.4.99.27: a tRNA uridine13 = a pseudouridine13 in tRNA ,
5.4.99.28: a tRNA uridine32 = a pseudouridine32 in tRNA ,
5.5.1.4: D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate ,
5.5.1.4: β-D-glucose 6-phosphate = 1D-myo-inositol 3-monophosphate ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.2: a carboxylate + ATP + coenzyme A → an acyl-CoA + AMP + diphosphate ,
6.2.1.3: decanoate + ATP + coenzyme A → decanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: linoleate + ATP + coenzyme A → linoleoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: palmitate + ATP + coenzyme A → palmitoyl-CoA + AMP + diphosphate ,
6.2.1.3: octanoate + ATP + coenzyme A → octanoyl-CoA + AMP + diphosphate ,
6.2.1.3: oleate + ATP + coenzyme A → oleoyl-CoA + AMP + diphosphate ,
6.2.1.3: ATP + α-linolenate + coenzyme A → α-linolenoyl-CoA + AMP + diphosphate ,
6.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: phytenate + ATP + coenzyme A → phytenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: pristanate + ATP + coenzyme A → pristanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a long-chain fatty acid + ATP + coenzyme A → a long-chain acyl-CoA + AMP + diphosphate ,
6.2.1.3: icosapentaenoate + ATP + coenzyme A → eicosapentaenoyl-CoA + AMP + diphosphate ,
6.2.1.3: (15Z)-tetracosenoate + ATP + coenzyme A → (Z)-15-tetracosenoyl-CoA + AMP + diphosphate ,
6.2.1.4: succinate[mitochondrial lumen] + GTP[mitochondrial lumen] + coenzyme A[mitochondrial lumen] ↔ succinyl-CoA[mitochondrial lumen] + GDP[mitochondrial lumen] + phosphate[mitochondrial lumen] ,
6.2.1.5: succinate[mitochondrial lumen] + ATP[mitochondrial lumen] + coenzyme A[mitochondrial lumen] ↔ succinyl-CoA[mitochondrial lumen] + ADP[mitochondrial lumen] + phosphate[mitochondrial lumen] ,
6.2.1.7: (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + ATP + coenzyme A → (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + AMP + diphosphate ,
6.2.1.7: ATP + cholate + coenzyme A → AMP + choloyl-CoA + diphosphate ,
6.2.1.12: 4-coumarate + ATP + coenzyme A → 4-coumaryl-CoA + AMP + diphosphate ,
6.2.1.15: arachidonate + ATP + coenzyme A → arachidonyl-CoA + AMP + diphosphate ,
6.2.1.16: acetoacetate + ATP + coenzyme A → acetoacetyl-CoA + AMP + diphosphate ,
6.2.1.24: phytanate + ATP + coenzyme A → phytanoyl-CoA + AMP + diphosphate ,
6.2.1.28: ATP + (25R)-3α,7α-dihydroxy-5-β-cholestanate + coenzyme A → AMP + (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + diphosphate ,
6.2.1.41: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + coenzyme A → 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate ,
6.2.1.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.-: 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoate + ATP + coenzyme A → OPC8-CoA + AMP + diphosphate ,
6.2.1.-: 3-oxocholest-4-en-26-oate + ATP + coenzyme A → 3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate ,
6.3.1.1: L-aspartate + ammonium + ATP → L-asparagine + AMP + diphosphate + H+ ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.14: a diphthine-[translation elongation factor 2] + ammonium + ATP → a diphthamide-[translation elongation factor 2] + AMP + diphosphate + H+ ,
6.3.2.2: L-cysteine + L-glutamate + ATP → γ-L-glutamyl-L-cysteine + ADP + phosphate + H+ ,
6.3.2.3: glycine + γ-L-glutamyl-L-cysteine + ATP → glutathione + ADP + phosphate + H+ ,
6.3.2.5: (R)-4'-phosphopantothenate + L-cysteine + CTP → R-4'-phosphopantothenoyl-L-cysteine + CMP + diphosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.11: 4-aminobutanoate + L-histidine + ATP → homocarnosine + ADP + phosphate + H+ ,
6.3.2.11: β-alanine + L-histidine + ATP → carnosine + ADP + phosphate + H+ ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: (R)-4'-phosphopantothenate + L-cysteine + ATP → R-4'-phosphopantothenoyl-L-cysteine + AMP + diphosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: an N5-formyl-tetrahydrofolate + ATP → a 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.3: a tetrahydrofolate + ATP + formate → 10-formyl-tetrahydropteroyl-[γ-Glu](n) + ADP + phosphate ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP ↔ L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.11: an apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + biotin + ATP → a holo [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + AMP + diphosphate ,
6.3.4.13: ATP + 5-phospho-β-D-ribosylamine + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.16: ammonium + CO2 + 2 ATP + H2O → carbamoyl-phosphate + 2 ADP + phosphate + 3 H+ ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → L-glutamate + AMP + NAD+ + diphosphate + H+ ,
6.3.5.2: XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+ ,
6.3.5.4: L-glutamine + L-aspartate + ATP + H2O → L-glutamate + L-asparagine + AMP + diphosphate + H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.4.1.1: hydrogen carbonate[mitochondrial lumen] + pyruvate[mitochondrial lumen] + ATP[mitochondrial lumen] → oxaloacetate[mitochondrial lumen] + ADP[mitochondrial lumen] + phosphate[mitochondrial lumen] + H+[mitochondrial lumen] ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.3: ATP + hydrogen carbonate + propanoyl-CoA → (S)-methylmalonyl-CoA + ADP + phosphate + H+ ,
6.4.1.4: hydrogen carbonate + 3-methylcrotonyl-CoA + ATP → ADP + 3-methylglutaconyl-CoA + phosphate + H+ ,
6.5.1.6: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
6.5.1.7: (deoxynucleotides)(m) + ATP + (deoxynucleotides)(n) → (deoxynucleotides)(n+m) + AMP + diphosphate ,
6.-.-.-: a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + H+ → a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
L-arginine[extracellular space] → L-arginine[cytosol] ,
L-asparagine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-asparagine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
2 hydrogen carbonate[extracellular space] + Na+[extracellular space] + chloride[cytosol] → 2 hydrogen carbonate[cytosol] + Na+[cytosol] + chloride[extracellular space] ,
Na+[extracellular space] + phosphate[extracellular space] → Na+[cytosol] + phosphate[cytosol] ,
L-phenylalanine[extracellular space] → L-phenylalanine[cytosol] ,
glycine[cytosol] → glycine[vesicle lumen] ,
Zn2+[extracellular space] → Zn2+[cytosol] ,
L-ornithine[cytosol] → L-ornithine[mitochondrial lumen] ,
an O-acyl-L-carnitine[mitochondrial lumen] + L-carnitine[mitochondrial intermembrane space] → an O-acyl-L-carnitine[mitochondrial intermembrane space] + L-carnitine[mitochondrial lumen] ,
L-isoleucine[extracellular space] + Na+[extracellular space] → L-isoleucine[cytosol] + Na+[cytosol] ,
acetoacetate[extracellular space] + H+[extracellular space] → acetoacetate[cytosol] + H+[cytosol] ,
chloride[extracellular space] + hydrogen carbonate[cytosol] → chloride[cytosol] + hydrogen carbonate[cytosol] ,
L-glutamine[extracellular space] + L-arginine[cytosol] → L-glutamine[cytosol] + L-arginine[extracellular space] ,
a monocarboxylate[extracellular space] + H+[extracellular space] → a monocarboxylate[cytosol] + H+[cytosol] ,
L-serine[extracellular space] + Na+[extracellular space] → L-serine[cytosol] + Na+[cytosol] ,
2 hydrogen carbonate[extracellular space] + Na+[extracellular space] → 2 hydrogen carbonate[cytosol] + Na+[cytosol] ,
Ca2+[extracellular space] + Li+[cytosol] → Ca2+[cytosol] + Li+[extracellular space] ,
Ca2+[mitochondrial intermembrane space] → Ca2+[mitochondrial lumen] ,
glycine[extracellular space] + Na+[extracellular space] → glycine[cytosol] + Na+[cytosol] ,
L-histidine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-histidine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
Ca2+[cytosol] + 4 Na+[extracellular space] + K+[cytosol] → Ca2+[extracellular space] + 4 Na+[cytosol] + K+[extracellular space] ,
acetyl-CoA[cytosol] → acetyl-CoA[endoplasmic reticulum lumen] ,
L-tryptophan[extracellular space] → L-tryptophan[cytosol] ,
L-alanine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-alanine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
β-D-glucose[extracellular space] → β-D-glucose[cytosol] ,
hydrogen carbonate[extracellular space] + Na+[extracellular space] + chloride[cytosol] → hydrogen carbonate[cytosol] + Na+[cytosol] + chloride[extracellular space] ,
L-tyrosine[extracellular space] → L-tyrosine[cytosol] ,
Na+[extracellular space] → Na+[cytosol] ,
(R)-noradrenaline[extracellular space] + Na+[extracellular space] → (R)-noradrenaline[cytosol] + Na+[cytosol] ,
3'-phosphoadenylyl-sulfate[cytosol] → 3'-phosphoadenylyl-sulfate[golgi lumen] ,
(R)-3-hydroxybutanoate[extracellular space] + H+[extracellular space] → (R)-3-hydroxybutanoate[cytosol] + H+[cytosol] ,
4-aminobutanoate[cytosol] → 4-aminobutanoate[vesicle lumen] ,
4-aminobutanoate[extracellular space] + Na+[extracellular space] + chloride[extracellular space] → 4-aminobutanoate[cytosol] + Na+[cytosol] + chloride[cytosol] ,
D-glucose[extracellular space] + 2 Na+[extracellular space] → D-glucose[cytosol] + 2 Na+[cytosol] ,
L-valine[extracellular space] + Na+[extracellular space] → L-valine[cytosol] + Na+[cytosol] ,
lactate[extracellular space] + H+[extracellular space] → lactate[cytosol] + H+[cytosol] ,
L-cystine[extracellular space] → L-cystine[cytosol] ,
an mRNA + H2O = an RNase product with a 3' phosphate + an RNase product with a 5' OH ,
L-glutamate[cytosol] → L-glutamate[vesicle lumen] ,
L-alanine[extracellular space] + Na+[extracellular space] → L-alanine[cytosol] + Na+[cytosol] ,
L-glutamate[extracellular space] + Na+[extracellular space] → L-glutamate[cytosol] + Na+[cytosol] ,
GDP-L-fucose[cytosol] → GDP-L-fucose[golgi lumen] ,
(S)-reticuline → 1,2-dehydroreticulinium + 2 H+ ,
L-serine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-serine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
Na+[extracellular space] + H+[cytosol] → Na+[cytosol] + H+[extracellular space] ,
myo-inositol[extracellular space] + H+[extracellular space]myo-inositol[cytosol] + H+[cytosol] ,
L-leucine[extracellular space] → L-leucine[cytosol] ,
glycine[extracellular space] + Na+[extracellular space] + H+[cytosol] → glycine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
borate[extracellular space] + 2 Na+[extracellular space] → borate[cytosol] + 2 Na+[cytosol] ,
chloride[extracellular space] + Na+[extracellular space] + glycine betaine[extracellular space] → chloride[cytosol] + Na+[cytosol] + glycine betaine[cytosol] ,
acetate[extracellular space] + H+[extracellular space] → acetate[cytosol] + H+[cytosol] ,
a neutral amino acid[extracellular space] + Na+[extracellular space] → a neutral amino acid[cytosol] + Na+[cytosol] ,
chloride[cytosol] → chloride[endosome lumen] ,
Ca2+[cytosol] + Na+[extracellular space] ↔ Ca2+[extracellular space] + Na+[cytosol] ,
L-leucine[extracellular space] + Na+[extracellular space] → L-leucine[cytosol] + Na+[cytosol] ,
pyruvate[extracellular space] + H+[extracellular space] → pyruvate[cytosol] + H+[cytosol] ,
K+[extracellular space] ↔ K+[cytosol] ,
chloride[nuclear lumen] → chloride[cytosol] ,
L-ascorbate[extracellular space] + 2 Na+[extracellular space] → L-ascorbate[cytosol] + 2 Na+[cytosol] ,
L-methionine[extracellular space] + Na+[extracellular space] → L-methionine[cytosol] + Na+[cytosol] ,
acetylcholine[cytosol] + H+[vesicle lumen] → acetylcholine[vesicle lumen] + H+[cytosol] ,
a neutral amino acid[extracellular space] + 2 Na+[cytosol] + chloride[cytosol] → a neutral amino acid[cytosol] + 2 Na+[cytosol] + chloride[cytosol] ,
L-glutamine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-glutamine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
choline[extracellular space] + Na+[extracellular space] + chloride[extracellular space] → choline[cytosol] + Na+[cytosol] + chloride[cytosol] ,
myo-inositol[extracellular space] + Na+[extracellular space]myo-inositol[cytosol] + Na+[cytosol] ,
L-glutamate[in] + L-cystine[out] → L-cystine[in] + L-glutamate[out] ,
sn-glycerol 3-phosphate[mitochondrial intermembrane space]sn-glycerol 3-phosphate[cytosol] ,
dihydroxyacetone phosphate[mitochondrial intermembrane space] ↔ dihydroxyacetone phosphate[cytosol] ,
citrate[mitochondrial intermembrane space] ↔ citrate[cytosol] ,
citrate[mitochondrial lumen] + (S)-malate[mitochondrial intermembrane space] → citrate[mitochondrial intermembrane space] + (S)-malate[mitochondrial lumen] ,
(S)-1-pyrroline-5-carboxylate[in] ↔ (S)-1-pyrroline-5-carboxylate[out] ,
ammonia[in] ↔ ammonia[out] ,
L-glutamate[mitochondrial lumen] + H+[mitochondrial lumen] ↔ L-glutamate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] ,
oxaloacetate[mitochondrial intermembrane space] ↔ oxaloacetate[cytosol] ,
2-oxoglutarate[mitochondrial intermembrane space] ↔ 2-oxoglutarate[cytosol] ,
(S)-malate[mitochondrial intermembrane space] ↔ (S)-malate[cytosol] ,
L-aspartate[mitochondrial intermembrane space] ↔ L-aspartate[cytosol] ,
L-glutamate[mitochondrial intermembrane space] ↔ L-glutamate[cytosol] ,
L-glutamate[out] + L-aspartate[in] + H+[out] → L-glutamate[in] + L-aspartate[out] + H+[in] ,
(S)-malate[mitochondrial lumen] + 2-oxoglutarate[mitochondrial intermembrane space] ↔ (S)-malate[mitochondrial intermembrane space] + 2-oxoglutarate[mitochondrial lumen] ,
oxygen[in] ↔ oxygen[out] ,
phosphate[mitochondrial intermembrane space] ↔ phosphate[cytosol] ,
H+[mitochondrial intermembrane space] ↔ H+[cytosol] ,
H2O[mitochondrial lumen] ↔ H2O[mitochondrial intermembrane space] ,
phosphate[mitochondrial lumen] + H+[mitochondrial lumen] ← phosphate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] ,
ATP[mitochondrial intermembrane space] ↔ ATP[cytosol] ,
ADP[mitochondrial intermembrane space] + ATP[mitochondrial lumen] → ADP[mitochondrial lumen] + ATP[mitochondrial intermembrane space] ,
L-carnitine[mitochondrial intermembrane space] ↔ L-carnitine[cytosol] ,
an O-acyl-L-carnitine[mitochondrial intermembrane space] ↔ an O-acyl-L-carnitine[cytosol] ,
8 H+[in] → 8 H+[out] ,
pyruvate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] → pyruvate[mitochondrial lumen] + H+[mitochondrial lumen] ,
pyruvate[cytosol] ↔ pyruvate[mitochondrial intermembrane space] ,
D-serine[extracellular space] → D-serine[cytosol] ,
Na+[extracellular space] + L-cysteine[extracellular space] → Na+[cytosol] + L-cysteine[cytosol] ,
Na+[extracellular space] + L-glutamine[extracellular space] → L-glutamine[cytosol] + Na+[cytosol] ,
glycine[extracellular space] + H+[extracellular space] → glycine[cytosol] + H+[cytosol] ,
L-glutamate[extracellular space] + Na+[extracellular space] → L-glutamate[cytosol] + Na+[cytosol] ,
K+[out] → K+[in] ,
K+[out] → K+[in] ,
K+[out] → K+[in] ,
H2O[mitochondrial intermembrane space] ↔ H2O[cytosol] ,
ADP[mitochondrial intermembrane space] ↔ ADP[cytosol] ,
Na+[extracellular space] + L-threonine[extracellular space] → Na+[cytosol] + L-threonine[cytosol] ,
L-proline[extracellular space] + H+[extracellular space] → L-proline[cytosol] + H+[cytosol] ,
L-alanine[extracellular space] + H+[extracellular space] → L-alanine[cytosol] + H+[cytosol] ,
L-aspartate[extracellular space] + Na+[extracellular space] → L-aspartate[cytosol] + Na+[cytosol] ,
4 H+[in] → 4 H+[out] ,
an L-cysteine-S-conjugate = a thiol + 2-aminoprop-2-enoate + H+ ,
2 H+[in] → 2 H+[out] ,
a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-carboxy-3-(methylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
13'-hydroxy-α-tocopherol → 5'-α-carboxylmethylbutylhydroxychroman ,
aldehydo-D-ribose ↔ D-ribopyranose ,
2 L-arginine + 2 NADPH + 2 H+ + 2 oxygen = 2 Nω-hydroxy-L-arginine + 2 NADP+ + 2 H2O ,
tyramine → dopamine ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
2-oxo-4-methylthiobutanoate + hydroxyl radical → ethylene + methanethiol + 2 CO2 ,
7-O-acetylsalutaridinol → thebaine + acetate + H+ ,
3,3',5,5'-tetraiodothyronamine + a reduced electron acceptor → 3,3',5-triiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
arachidonate + a reduced electron acceptor + oxygen → 15S-hydroxypentaenoate + an oxidized electron acceptor + H2O ,
L-tyrosine + 0.5 oxygen → L-dopa ,
simvastatin lactone + H2O → simvastatin acid + H+ ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
4,4-dimethylzymosterol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
3-iodo-L-tyrosine + iodide + NADP+ ← 3,5-diiodo-L-tyrosine + NADPH + H+ ,
formaldehyde + a tetrahydrofolate → a 5,10-methylene-tetrahydrofolate + H2O ,
4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + 2 H2O ,
5-methoxyindoleacetaldehyde + a reduced electron acceptor → 5-methoxytryptophol + an oxidized electron acceptor ,
4-oxo-4-(3-pyridyl)-N-methylbutanamide → 4-oxo-4-(3-pyridyl)-butanoate ,
L-dehydro-ascorbate + NADPH → L-ascorbate + NADP+ ,
24,25-dihydrolanosterol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADP+ + H2O ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
S-adenosyl-L-methionine + an N terminal N-methyl-PPK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-PPK-[protein] + H+ ,
(25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + an oxidized electron acceptor → (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + a reduced electron acceptor ,
S-adenosyl-L-methionine + an N terminal N-methyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-(A/S)PK-[protein] + H+ ,
NADH + H2O → (S)-NADHX ,
5β-cholestane-3α,7α,12α-triol + NADPH + oxygen + H+ → (25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADP+ + H2O ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate ,
a [protein] N6,N6-dimethyl-L-lysine + 2-oxoglutarate + oxygen = a [protein] N6-methyl-L-lysine + succinate + formaldehyde + CO2 ,
prephytoene diphosphate = 15-cis-phytoene + diphosphate ,
(9Z,15Z)-12,13-epoxy-octadeca-9,15-dienoate + H2O = (9Z,15Z)-12,13-dihydroxyoctadeca-9,15-dienoate ,
17-hydro(p)docosahexaenoate + an oxidized electron acceptor + H2O → 4S-hydroperoxy,17R-H-docosahexaenoate + a reduced electron acceptor ,
arachidonate + NADPH + oxygen + H+ → (15R)-hydroxyeicosapentaenoate + NADP+ + H2O ,
4-oxoglutaramate + H2O → 2-oxoglutarate + ammonium ,
5,6-dihydroxyindole-2-carboxylate + 2 H+ + oxygen → indole-5,6-quinone-2-carboxylate + 2 H2O ,
a 2(R)-hydroperoxy fatty acid + H+ → a fatty aldehyde + CO2 + H2O ,
14-hydroxylanosterol + NADPH + H+ + oxygen → 14-oxolanosterol + NADP+ + 2 H2O ,
melatonin + H2O → 5-methoxytryptamine + acetate + H+ ,
4,4-dimethyl-5α-cholest-7-en-3β-ol + NAD(P)H + oxygen + H+ = 4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + NAD(P)+ + H2O ,
α-D-ribose 5-phosphate → β-D-ribose 5-phosphate ,
nornicotine + H2O → norcotinine + 5 H+ ,
keto-L-sorbose ↔ L-sorbopyranose ,
3-methoxy-4-hydroxyphenylpyruvate + NADH + H+ ↔ 3-methoxy-4-hydroxyphenyllactate + NAD+ ,
cyclic ADP-ribose + H2O = ADP-D-ribose + H+ ,
15,15'-dihydroxy-β-carotene + an oxidized electron acceptor = 2 all-trans-retinal + a reduced electron acceptor ,
(25R)-5β-cholestane-3α,7α,26-triol + NADPH + H+ + oxygen → (25R)-3α,7α-dihydroxy-5β-cholestan-26-al + NADP+ + 2 H2O ,
cyclic-2,3-O-oxalyl-L-threonate → cyclic- 3,4-O-oxalyl-L-threonate ,
2-aminoprop-2-enoate + H+ + H2O → pyruvate + ammonium ,
glutathione + intracellular S0 → S-sulfanylglutathione ,
a vernolate + H2O = (9Z)-12,13-dihydroxyoctadeca-9-enoate ,
5,6-epoxy,18R-hydroxy-eicosapentaenoate + 2 H+ = resolvin E2 ,
3,3',5'-triiodothyronamine + a reduced electron acceptor → 3',5'-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
3,3'-diiodothyronine + a reduced electron acceptor → 3'-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
4-imidazolone-5-propionate + H2O → formyl-L-isoglutamine ,
19-hydroxytestosterone + a reduced flavoprotein + oxygen → 19-oxo-testosterone + an oxidized flavoprotein + 2 H2O ,
2-oxoadipate + coenzyme A + NAD+ → CO2 + glutaryl-CoA + NADH ,
squalene + NAD(P)+ + diphosphate = presqualene diphosphate + NAD(P)H + H+ ,
(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADPH + oxygen → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + NADP+ + H2O ,
bupropion + 2 H+ = erythrohydrobupropion ,
XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+ ,
4,4-dimethyl-5α-cholesta-8-en-3-β-ol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+ ↔ (E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein ,
D-myo-inositol (1,3,4,6)-tetrakisphosphate = D-myo-inositol (1,3,4,5)-tetrakisphosphate ,
D-arabinofuranose ↔ D-arabinopyranose ,
CTP + hydroxyl radical → 5-hydroxy-CTP + H+ ,
aldehydo-D-mannose → β-D-mannose ,
3,5,3'-triiodo-L-thyronine → 3,3',5-triiodothyroacetate ,
an [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + NADH + H+ = an [eIF5A-precursor]-deoxyhypusine + NAD+ ,
2 L-dehydro-ascorbate + oxygen → 2 cyclic-2,3-O-oxalyl-L-threonate + 2 H+ ,
3'-iodothyronamine + a reduced electron acceptor → thyronamine + iodide + an oxidized electron acceptor + H+ ,
5,6-epoxy,18R-hydroxy-eicosapentaenoate + H2O = resolvin E1 ,
ammonia + H+ ↔ ammonium ,
19-hydroxyandrostenedione + a reduced flavoprotein + oxygen → 19-oxoandrostenedione + an oxidized flavoprotein + 2 H2O ,
2-oxoadipate + ammonium + NAD+ ← 2-aminomuconate + NADH + H2O + 2 H+ ,
4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
a 2-[(3S)-3-carboxy-3-(methylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
a 2-monoglyceride → a 1-monoglyceride ,
4-(3-pyridyl)-butanoate → 3-pyridylacetate ,
an Fe(II)-siderophore + H+ → a siderophore + Fe2+ ,
4-coumaryl-CoA + coenzyme A + NAD+ + H2O → 4-hydroxybenzoyl-CoA + acetyl-CoA + NADH + H+ ,
(3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H2O + H+ ↔ L-4-hydroxyglutamate semialdehyde ,
spermidine + NAD+ = dehydrospermidine + NADH + H+ ,
3-hydroxy-N6,N6,N6-trimethyl-L-lysine → 4-trimethylammoniobutanal + glycine ,
pre-vitamin D3 + heat → vitamin D3 ,
L-dehydro-ascorbate + H2O → dehydroascorbate (bicyclic form) ,
3,3'-diiodothyronamine + a reduced electron acceptor → 3-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
icosapentaenoate + a reduced electron acceptor + oxygen → 18R-hydroxy-eicosapentaenoate + an oxidized electron acceptor + H2O ,
ribose-1-arsenate + dihydrolipoate + H+ → D-ribofuranose + arsenite + (R)-lipoate ,
3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)H + oxygen = 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + NAD(P)+ + H2O ,
5'-α-carboxylmethylbutylhydroxychroman → α-carboxyethylhydroxychroman ,
adenine + hydroxyl radical → isoguanine + H+ ,
4-oxo-4-(3-pyridyl)-butanoate + 2 H+ → 4-hydroxy-4-(3-pyridyl)-butanoate ,
sphingosine 1-phosphate + H2O → sphingosine + phosphate ,
4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate → xanthurenate + H+ + H2O ,
2 Nω-hydroxy-L-arginine + NADPH + 2 oxygen = 2 L-citrulline + 2 nitric oxide + NADP+ + 2 H2O + H+ ,
3,4-dihydroxyphenylpyruvate + H+ → 3,4-dihydroxyphenylacetaldehyde + CO2 ,
(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + NAD+ → 3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + NADH + H+ ,
hydrogen peroxide + Fe2+ → hydroxyl radical + Fe3+ + OH- ,
2 geranylgeranyl diphosphate = prephytoene diphosphate + diphosphate ,
docosahexaenoate + 2 a reduced electron acceptor + 2 oxygen → 17S-hydro(p)docosahexaenoate + 2 an oxidized electron acceptor + 2 H2O ,
3,3',5,5'-tetraiodothyronamine + a reduced electron acceptor → 3,3',5'-triiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
15S-hydroxypentaenoate + oxygen → lipoxin A4 ,
n melanochrome → eumelanin ,
4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + 2 H2O ,
a D-glucosyl-N-acylsphinganine + NADPH + oxygen + H+ = a D-glucosyl-N-acylsphingosine + NADP+ + 2 H2O ,
4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → 4α-carboxy-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
melatonin + hydrogen peroxide → N1-acetyl-N2-formyl-5-methoxykynuramine + 2 H+ ,
cotinine → cotinine N-oxide ,
L-ascorbate + an oxidized electron acceptor + 2 H+ → monodehydroascorbate radical + a reduced electron acceptor ,
4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADP+ + 2 H2O ,
D-altropyranose ↔ aldehydo-D-altrose ,
sphingosine + ATP → sphingosine 1-phosphate + ADP + H+ ,
an [L-cysteine desulfurase] L-cysteine persulfide + a ThiI sulfur-carrier protein = an [L-cysteine desulfurase]-L-cysteine + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
di-trans, poly-cis-polyprenyl diphosphate (C80) + H2O → di-trans, poly-cis-polyprenol (C80) + diphosphate ,
[thyroglobulin]-triiodothyronine + H2O → 3,5,3'-triiodo-L-thyronine + [unspecified degradation products] ,
NADH + H2O → (R)-NADHX ,
L-rhamnopyranose ↔ L-rhamnofuranose ,
2 L-cysteine → lanthionine + hydrogen sulfide ,
3,3',5'-triiodo-L-thyronine + a reduced electron acceptor → 3',5'-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
(15R)-hydroxyeicosapentaenoate + oxygen → 15 epi-lipoxin A4 ,
indole-5,6-quinone + indole-5,6-quinone-2-carboxylate → melanochrome ,
14-oxolanosterol + NADPH + oxygen → 14-demethyllanosterol + formate + NADP+ + H2O ,
3-oxo-3-phenylpropanoyl-CoA + coenzyme A = benzoyl-CoA + acetyl-CoA ,
ethanol + NADPH + oxygen + H+ → acetaldehyde + NADP+ + 2 H2O ,
β-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
2-aminoprop-2-enoate → 2-iminopropanoate ,
norcotinine → 4-oxo-4-(3-pyridyl)-butanamide ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
3-methoxy-4-hydroxyphenylpyruvate → homovanillate ,
dATP + hydroxyl radical → 2-hydroxy-dATP + H+ ,
5-hydroxyindole acetaldehyde + L-cysteine ↔ 5-hydroxyindole thiazolidine carboxylate + H2O ,
NADP+ = 2'-phospho-cyclic ADP-ribose + nicotinamide ,
a 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one → a 3-isopropenyl-6-oxoheptanoate + H+ ,
S-adenosyl-L-methionine + an N terminal N,N-dimethyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein] + H+ ,
(25R)-3α,7α-dihydroxy-5β-cholestan-26-al + NADPH + oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + NADP+ + H2O ,
(5S)-HPETE → leukotriene A4 + H2O ,
2-keto-6-aminocaproate + hydrogen peroxide → 5-aminopentanoate + CO2 + H2O ,
(9Z,12Z)-15,16-epoxyoctadeca-9,12-dienoate + H2O = (9Z,12Z)-15,16-dihydroxyoctadeca-9,12-dienoate ,
ammeline + H2O = ammelide + ammonium ,
3',5'-diiodothyronamine + a reduced electron acceptor → 3'-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
3'-monoiodothyronine + a reduced electron acceptor → L-thyronine + iodide + an oxidized electron acceptor + H+ ,
formyl-L-isoglutamine + H2O → L-isoglutamine + formate ,
1-(3-aminopropyl)-4-aminobutanal → 1-(3-aminopropyl)-pyrrolinium + H2O ,
19-oxo-testosterone + a reduced flavoprotein + oxygen → 17β-estradiol + formate + an oxidized flavoprotein + H2O + H+ ,
L-dopachrome + H+ → 5,6-dihydroxyindole + CO2 ,
bupropion → 3-chlorobenzoate ,
4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + 2 H2O ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
aldehydo-L-arabinose ↔ L-arabinopyranose ,
aldehydo-D-xylose ↔ a D-xylopyranose ,
(R)-methylmalonate-semialdehyde ↔ (S)-methylmalonate-semialdehyde ,
sulfite + 2 Fe3+ + H2O = sulfate + 2 Fe2+ + 2 H+ ,
L-thyroxine = 3-iodothyronamine ,
all-trans-β-carotene + a reduced electron acceptor + oxygen = β-carotene 15,15' epoxide + an oxidized electron acceptor + H2O ,
2,3-dioxo-L-gulonate → 2-carboxy-L-xylonolactone ,
L-erythro-5,6,7,8-tetrahydrobiopterin + NADP+ = 6-lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ ,
2-oxoglutarate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + NAD+[mitochondrial lumen] → succinyl-CoA[mitochondrial lumen] + CO2[mitochondrial lumen] + NADH[mitochondrial lumen] ,
Δ1-piperideine-2-carboxylate + H+ + H2O ← 2-keto-6-aminocaproate ,
L-lysine + 2-oxoglutarate → 2-keto-6-aminocaproate + L-glutamate ,
3,3',5-triiodothyronamine + a reduced electron acceptor → 3,5-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
docosahexaenoate + 2 a reduced electron acceptor + 2 oxygen → 17-hydro(p)docosahexaenoate + 2 an oxidized electron acceptor + 2 H2O ,
3,3'-diiodothyronine + a reduced electron acceptor → 3-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
19-oxoandrostenedione + a reduced flavoprotein + oxygen → estrone + formate + an oxidized flavoprotein + H2O + H+ ,
2 monodehydroascorbate radical → L-ascorbate + L-dehydro-ascorbate + H+ ,
L-lyxopyranose → aldehydo-L-lyxose ,
D-galactopyranuronate ↔ aldehydo-D-galacturonate ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
dehydrospermidine + a [deoxyhypusine synthase]-L-lysine = a [deoxyhypusine synthase]-N-(4-aminobutylidene)-lysine + propane-1,3-diamine ,
dehydroascorbate (bicyclic form) + hydrogen peroxide → L-threonate + oxalate + 3 H+ ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
3,3'-diiodothyronamine + a reduced electron acceptor → 3'-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
18R-hydroxy-eicosapentaenoate + oxygen → 5S hydro(peroxy),18R-hydroxy-eicosapentaenoate ,
intracellular S0n + a thiol → intracellular S0n-1 + a perthiol ,
citrate[mitochondrial lumen]cis-aconitate[mitochondrial lumen] + H2O[mitochondrial lumen] ,
4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + NAD(P)H + H+ + oxygen = 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)+ + 2 H2O ,
4α-methyl-zymosterol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
pyruvate + hydroxylamine → pyruvic oxime + H2O ,
4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
2'-deoxyadenosine + hydroxyl radical → 2-hydroxydeoxyadenosine + H+ ,
4-hydroxy-4-(3-pyridyl)-butanoate → 4-(3-pyridyl)-3-butenoate ,
5-phospho-α-D-ribose 1-diphosphate + H2O = α-D-ribose 1,5-bisphosphate + phosphate + H+ ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
2 L-homocysteine → hydrogen sulfide + L-homolanthionine ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
2-aminomuconate 6-semialdehyde → picolinate + H2O ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
dopamine + 3,4-dihydroxyphenylacetaldehyde → S-norlaudanosoline + H2O ,
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NAD(P)H + H+ → 2-dehydro-3-deoxy-D-gluconate + NAD(P)+ ,
2 Fe2+ + 2 oxygen → 2 superoxide + 2 Fe3+ ,
17S-hydro(p)docosahexaenoate + a reduced electron acceptor + oxygen → 7S-hydroperoxy,17S-H-docosahexaenoate + an oxidized electron acceptor + H2O ,
3,3',5-triiodothyronamine + a reduced electron acceptor → 3,3'-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
cacodylate + 3 H+ → dimethylarsinous acid + H2O ,
4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
leucodopachrome + dopaquinone → L-dopachrome + L-dopa ,
N1-acetyl-N2-formyl-5-methoxykynuramine + H2O → N-acetyl-5-methoxykynurenamine + formate + H+ ,
cotinine → cotinine methonium ion ,
4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADPH + oxygen → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate + NADP+ + H2O ,
aldehydo-D-ribose ↔ D-ribofuranose ,
sphinganine + a long-chain acyl-CoA → a dihydroceramide + coenzyme A + H+ ,
4-(2-aminophenyl)-2,4-dioxobutanoate → kynurenate + H2O + H+ ,
di-trans, poly-cis-polyprenol (C80) + NADPH + H+ → a dolichol + NADP+ ,
[thyroglobulin]-L-thyroxine + H2O → L-thyroxine + [unspecified degradation products] ,
(24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA + NAD+ → 3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + NADH + H+ ,
2-amino-3-oxobutanoate + 2 H+ → aminoacetone + CO2 ,
a CDP-diacylglycerol + an L-1-phosphatidyl-glycerol → a cardiolipin + CMP + H+ ,
2-oxobutanoate + coenzyme A + NAD+ → propanoyl-CoA + CO2 + NADH ,
(15R)-hydroxyeicosapentaenoate + oxygen → 15 epi-lipoxin B4 ,
(R)-lactaldehyde + NAD+ + H2O → (R)-lactate + NADH + 2 H+ ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
L-tyrosine + iodide + NADP+ ← 3-iodo-L-tyrosine + NADPH ,
4α-methyl-cholesta-8-enol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
5-methoxyindoleacetaldehyde + an oxidized electron acceptor + H2O → 5-methoxyindole acetate + a reduced electron acceptor ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
5'-hydroxycotinine → 4-oxo-4-(3-pyridyl)-N-methylbutanamide ,
L-serine → 2-aminoprop-2-enoate + H+ + H2O ,
4-oxo-4-(3-pyridyl)-butanamide → 4-oxo-4-(3-pyridyl)-butanoate ,
aldehydo-L-fucose ↔ L-fucopyranose ,
a dihydroceramide + NAD(P)H + oxygen + H+ → an N-acylsphingosine + NAD(P)+ + 2 H2O ,
ATP + UTP + ammonium → ADP + CTP + phosphate + 2 H+ ,
2'-phospho-cyclic ADP-ribose + nicotinate = nicotinate-adenine dinucleotide phosphate ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
stearidonoyl-CoA + malonyl-CoA + 2 NADPH + 3 H+ → eicosatetraenoyl-CoA + CO2 + coenzyme A + 2 NADP+ + H2O ,
S-adenosyl-L-methionine + an N-terminal-PPK-[protein] → S-adenosyl-L-homocysteine + an N terminal N-methyl-PPK-[protein] + H+ ,
S-adenosyl-L-methionine + an N-terminal-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N-methyl-(A/S)PK-[protein] + H+ ,
(25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADPH + oxygen + H+ → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADP+ + 2 H2O ,
sulfite + H+ ↔ bisulfite ,
arachidonate + oxygen → (5S)-HPETE ,
(12Z,15Z)-9,10-epoxyoctadeca-12,15-dienoate + H2O = (12Z,15Z)-9,10-dihydroxyoctadeca-12,15-dienoate ,
3,5,3'-triiodo-L-thyronine + a reduced electron acceptor → 3,5-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
4-imidazolone-5-propionate + oxygen + H2O + 2 H+ → 4-oxoglutaramate + ammonium + formate ,
1-(3-aminopropyl)-pyrrolinium → 1,5-diazabicyclononane + H+ ,
aminocarboxymuconate semialdehyde → quinolinate + H2O ,
5,6-dihydroxyindole + 2 H+ + oxygen → indole-5,6-quinone + 2 H2O ,
lanosterol + NADPH + H+ + oxygen → 14-hydroxylanosterol + NADP+ + H2O ,
3-chlorobenzoate + glycine → m-chlorohippurate + H2O ,
L-threonine = (2Z)-2-aminobut-2-enoate + H2O + H+ ,
(S)-nicotine + H2O → nornicotine + formaldehyde + 2 H+ ,
L-arabinofuranose ↔ L-arabinopyranose ,
keto-D-fructose → β-D-fructofuranose ,
3-O-methyldopa + 2-oxoglutarate + H+ ↔ 3-methoxy-4-hydroxyphenylpyruvate + L-glutamate ,
NAD+ = cyclic ADP-ribose + nicotinamide ,
3,5,3'-triiodo-L-thyronine → thyronamine ,
β-carotene 15,15' epoxide + H2O = 15,15'-dihydroxy-β-carotene ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
5β-cholestane-3α,7α-diol + NADPH + H+ + oxygen → (25R)-5β-cholestane-3α,7α,26-triol + NADP+ + H2O ,
2-carboxy-L-xylonolactone + H2O → 2-carboxy-L-threo-pentonate + H+ ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
prephytoene diphosphate = all-trans-phytoene + diphosphate ,
(S)-2-amino-6-oxohexanoate ↔ (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + H2O + H+ ,
3,5-diiodothyronamine + a reduced electron acceptor → 3-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
17-hydro(p)docosahexaenoate + an oxidized electron acceptor + H2O → 7S-hydroperoxy,17R-H-docosahexaenoate + a reduced electron acceptor ,
3-monoiodothyronine + a reduced electron acceptor → L-thyronine + iodide + an oxidized electron acceptor + H+ ,
testosterone + a reduced flavoprotein + oxygen → 19-hydroxytestosterone + an oxidized flavoprotein + H2O ,
bupropion + 2 H+ = threohydrobupropion ,
2'-hydroxynicotine → pseudooxynicotine ,
α-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
D-arabinopyranose → aldehydo-D-arabinose ,
aldehydo-D-mannose → D-mannopyranose ,
(S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD(P)+ + 2 H2O = L-2-aminoadipate + NAD(P)H + H+ ,
L-cystathionine → (2Z)-2-aminobut-2-enoate + L-cysteine + H+ ,
(1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate → (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
L-thyroxine → tetraiodothyroacetate ,
a [deoxyhypusine synthase]-N-(4-aminobutylidene)-lysine + an [eIF5A-precursor]-lysine = an [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + a [deoxyhypusine synthase]-L-lysine + H+ ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
(S)-propane-1,2-diol + NAD+ ← acetol + NADH + H+ ,
L-cysteine + L-homocysteine → L-cystathionine + hydrogen sulfide ,
3-iodothyronamine + a reduced electron acceptor → thyronamine + iodide + an oxidized electron acceptor + H+ ,
5S hydro(peroxy),18R-hydroxy-eicosapentaenoate → resolvin E1 ,
cis-aconitate + H2O → D-threo-isocitrate ,
androst-4-ene-3,17-dione + a reduced flavoprotein + oxygen → 19-hydroxyandrostenedione + an oxidized flavoprotein + H2O ,
4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + 2 H2O ,
a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a diphthine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
2 L-ascorbate + hydrogen peroxide + 2 H+ → 2 monodehydroascorbate radical + 2 H2O ,
4-(3-pyridyl)-3-butenoate + 2 H+ → 4-(3-pyridyl)-butanoate ,
3-(4-hydroxyphenyl)lactate → 4-coumarate + H2O ,
D-glucopyranuronate ↔ aldehydo-D-glucuronate ,
aldehydo-D-glucose → D-glucopyranose ,
S-norlaudanosoline + 3 S-adenosyl-L-methionine → (S)-reticuline + 3 S-adenosyl-L-homocysteine + 3 H+ ,
7-dehydrocholesterol + UV light → pre-vitamin D3 ,
dehydroascorbate (bicyclic form) → 2,3-dioxo-L-gulonate + H+ ,
(S)-1-pyrroline-5-carboxylate[mitochondrial lumen] + NAD+[mitochondrial lumen] + 2 H2O[mitochondrial lumen] → L-glutamate[mitochondrial lumen] + NADH[mitochondrial lumen] + H+[mitochondrial lumen] ,
geranial ↔ neral ,
dopaquinone → leucodopachrome + H+ ,
neopinone → codeinone ,
5S hydro(peroxy),18R-hydroxy-eicosapentaenoate + a reduced electron acceptor → resolvin E2 + an oxidized electron acceptor + H2O ,
17S-hydro(p)docosahexaenoate + a reduced electron acceptor + oxygen → 4S-hydroperoxy,17S-H-docosahexaenoate + an oxidized electron acceptor + H2O ,
3,3',5'-triiodothyronamine + a reduced electron acceptor → 3,3'-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
15S-hydroxypentaenoate + oxygen → lipoxin B4 ,
betaine aldehyde hydrate ↔ betaine aldehyde + H2O ,
glycine + a tetrahydrofolate + NAD+ → a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH ,
2-oxoglutaramate → 2-hydroxy-5-oxoproline ,
2 indoxyl + oxygen → indigo + 2 H2O


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Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
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