Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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ends Feb 21th, 2015
Metabolic Modeling Tutorial
early discounted registration
ends Feb 21th, 2015
Metabolic Modeling Tutorial
early discounted registration
ends Feb 21th, 2015
Metabolic Modeling Tutorial
early discounted registration
ends Feb 21th, 2015
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Homo sapiens Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: 4-tyrosol + NAD+ = (4-hydroxyphenyl)acetaldehyde + NADH + H+ ,
1.1.1.1: a primary alcohol + NAD+ = an aldehyde + NADH + H+ ,
1.1.1.1: methionol + NAD+ = 3-methylthiopropanal + NADH + H+ ,
1.1.1.1: indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ ,
1.1.1.1: isobutanol + NAD+ ↔ isobutanal + NADH + H+ ,
1.1.1.1: phytol + NAD+ → phytenal + NADH + H+ ,
1.1.1.1: 3-methoxy-4-hydroxyphenylglycol + NAD+ ↔ 3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 2-methylbutanol + NAD+ = 2-methylbutanal + NADH + H+ ,
1.1.1.1: n-propanol + NAD+ = propanal + NADH + H+ ,
1.1.1.1: 2-phenylethanol + NAD+ = phenylacetaldehyde + NADH + H+ ,
1.1.1.1: 3,4-dihydroxyphenylglycol + NAD+ ← 3,4-dihydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 3-methylbutanol + NAD+ ↔ 3-methylbutanal + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: 5-hydroxytryptophol + NAD+ ← 5-hydroxyindole acetaldehyde + NADH + H+ ,
1.1.1.1: a secondary alcohol + NAD+ = a ketone + NADH + H+ ,
1.1.1.2: ethanol + NADP+ = acetaldehyde + NADPH + H+ ,
1.1.1.2: an alcohol + NADP+ = an aldehyde + NADPH + H+ ,
1.1.1.2: indole acetaldehyde + NADPH + H+ → indole-3-ethanol + NADP+ ,
1.1.1.8: sn-glycerol 3-phosphate + NAD+ ↔ dihydroxyacetone phosphate + NADH + H+ ,
1.1.1.9: xylitol + NAD+ = D-xylulose + NADH + H+ ,
1.1.1.10: xylitol + NADP+ ↔ L-xylulose + NADPH + H+ ,
1.1.1.14: D-sorbitol + NAD+ → keto-D-fructose + NADH + H+ ,
1.1.1.14: L-iditol + NAD+ = keto-L-sorbose + NADH + H+ ,
1.1.1.19: L-gulonate + NADP+aldehydo-D-glucuronate + NADPH + H+ ,
1.1.1.21: galactitol + NADP+ ↔ β-D-galactose + NADPH + H+ ,
1.1.1.21: L-arabitol + NADP+ ↔ L-arabinopyranose + NADPH + H+ ,
1.1.1.21: a sugar alcohol + NAD(P)+ = an aldose + NAD(P)H + H+ ,
1.1.1.22: UDP-α-D-glucose + 2 NAD+ + H2O → UDP-α-D-glucuronate + 2 NADH + 3 H+ ,
1.1.1.27: (S)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.29: D-glycerate + NAD+ = hydroxypyruvate + NADH + H+ ,
1.1.1.30: (R)-3-hydroxybutanoate + NAD+ ↔ acetoacetate + NADH + H+ ,
1.1.1.31: (S)-3-hydroxy-isobutanoate + NAD+ → (S)-methylmalonate-semialdehyde + NADH + H+ ,
1.1.1.34: (R)-mevalonate + coenzyme A + 2 NADP+ ← (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ ,
1.1.1.35: (S)-3-hydroxybutanoyl-CoA + NAD+ ↔ acetoacetyl-CoA + NADH + H+ ,
1.1.1.35: (S)-3-hydroxydecanoyl-CoA + NAD+ = 3-oxodecanoyl-CoA + NADH + H+ ,
1.1.1.35: a (3S)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.36: a (3R)-3-hydroxyacyl-CoA + NADP+ = a 3-oxoacyl-CoA + NADPH + H+ ,
1.1.1.36: (R)-3-hydroxybutanoyl-CoA + NADP+ = acetoacetyl-CoA + NADPH + H+ ,
1.1.1.36: (R)-3-hydroxyvaleryl-CoA + NADP+ = β-ketovaleryl-CoA + NADPH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ = pyruvate + CO2 + NADH ,
1.1.1.40: (S)-malate + NADP+ = CO2 + pyruvate + NADPH ,
1.1.1.41: D-threo-isocitrate[mitochondrial lumen] + NAD+[mitochondrial lumen] → CO2[mitochondrial lumen] + 2-oxoglutarate[mitochondrial lumen] + NADH[mitochondrial lumen] ,
1.1.1.42: D-threo-isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.45: L-gulonate + NAD+ → 3-keto-L-gulonate + NADH + H+ ,
1.1.1.47: D-glucopyranose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+ ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.50/1.1.1.209/1.1.1.213: androsterone + NAD(P)+ = 5α-androstane-3,17-dione + NAD(P)H + H+ ,
1.1.1.51: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+ ,
1.1.1.62: 17β-estradiol + NAD(P)+ → estrone + NAD(P)H + H+ ,
1.1.1.64: testosterone + NADP+ ← androst-4-ene-3,17-dione + NADPH + H+ ,
1.1.1.71: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ ,
1.1.1.77: (R)-propane-1,2-diol + NAD+ ← (R)-lactaldehyde + NADH + H+ ,
1.1.1.78: (R)-lactaldehyde + NAD+ ← methylglyoxal + NADH + H+ ,
1.1.1.79: glycolate + NADP+ = glyoxylate + NADPH + H+ ,
1.1.1.80: isopropanol + NADP+ → acetone + NADPH + H+ ,
1.1.1.81: D-glycerate + NAD(P)+ = hydroxypyruvate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.102: sphinganine + NADP+ ← 3-dehydrosphinganine + NADPH + H+ ,
1.1.1.105: all-trans-retinol + NAD+all-trans-retinal + NADH + H+ ,
1.1.1.105: an all-trans retinol-[cellular-retinol-binding-protein] + NAD+ → an all-trans retinal-[cellular-retinol-binding-protein] + NADH + H+ ,
1.1.1.112: 1-indanol + NAD(P)+ = indanone + NAD(P)H + H+ ,
1.1.1.141: prostaglandin E2 + NAD+ = (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprosta-13-enoate + NADH + H+ ,
1.1.1.145: 17-α-hydroxypregnenolone + NAD+ = pregn-5-ene-3,20-dione-17-ol + NADH + H+ ,
1.1.1.145: pregnenolone + NAD+ → pregn-5-ene-3,20-dione + NADH + H+ ,
1.1.1.145: dehydroepiandrosterone + NAD+ → 5-androstene-3,17-dione + NADH + H+ ,
1.1.1.145: a 3β-hydroxy-δ5-steroid + NAD+ = a 3-oxo-δ5-steroid + NADH + H+ ,
1.1.1.146: an 11-β-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+ ,
1.1.1.149: (20S)-17,20-dihydroxypregn-4-en-3-one + NAD(P)+ = 17-α-hydroxyprogesterone + NAD(P)H + H+ ,
1.1.1.153: L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP+ ← 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ ,
1.1.1.153: L-erythro-7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+ ,
1.1.1.170: 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + NAD(P)+ = CO2 + 4α-methyl-5α-cholest-7-en-3-one + NAD(P)H ,
1.1.1.170: 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ → 5α-cholesta-8,24-dien-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ → 4α-methyl-5α-cholesta-8-en-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-5α-cholesta-8-en-3β-ol + NAD(P)+ → 5α-cholesta-8-en-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ → 3-dehydro-4-methylzymosterol + CO2 + NAD(P)H ,
1.1.1.178: 2-methyl-3-hydroxybutyryl-CoA + NAD+ → 2-methylacetoacetyl-CoA + NADH + H+ ,
1.1.1.179: a D-xylopyranose + NADP+ ↔ D-xylonolactone + NADPH + H+ ,
1.1.1.181: 7α-hydroxycholesterol + NAD+ → 7α-hydroxycholest-4-en-3-one + NADH + H+ ,
1.1.1.184: a secondary alcohol + NADP+ = a ketone + NADPH + H+ ,
1.1.1.188: prostaglandin F + NADP+ = prostaglandin D2 + NADPH + H+ ,
1.1.1.189: prostaglandin F + NADP+ = prostaglandin E2 + NADPH + H+ ,
1.1.1.197: (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoate + NADP+ = (13E)-11-α-hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.210: 5-α-androstan-3β,17β-diol + NADP+ = 5-α-dihydrotestosterone + NADPH + H+ ,
1.1.1.211: a long-chain (3S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.213: 5β-cholestane-3α,7α-diol + NAD(P)+ ← 7α-hydroxy-5β-cholestan-3-one + NAD(P)H + H+ ,
1.1.1.213: 5β-cholestane-3α,7α,12α-triol + NAD(P)+ ← 7α,12α-dihydroxy-5β-cholestan-3-one + NAD(P)H + H+ ,
1.1.1.213: allopregnanolone + NAD(P)+ ↔ 5-α-pregnane-3,20-dione + NAD(P)H + H+ ,
1.1.1.213: 5-α-androstan-3α,17β-diol + NAD(P)+ = 5-α-dihydrotestosterone + NAD(P)H + H+ ,
1.1.1.216: (2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ ,
1.1.1.218: morphine + NAD(P)+ ← morphinone + NAD(P)H + H+ ,
1.1.1.225: chlordecone alcohol + NADP+ = chlordecone + NADPH + H+ ,
1.1.1.237: 3-(4-hydroxyphenyl)lactate + NAD+ ← 4-hydroxyphenylpyruvate + NADH + H+ ,
1.1.1.239: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH + H+ ,
1.1.1.247: codeine + NADP+ ← codeinone + NADPH + H+ ,
1.1.1.248: salutaridinol + NADP+ ← salutaridine + NADPH + H+ ,
1.1.1.263: 1,5-anhydro-D-glucitol + NADP+ ← 1,5-anhydro-D-fructose + NADPH + H+ ,
1.1.1.270: zymosterol + NADP+ ← 5α-cholesta-8,24-dien-3-one + NADPH + H+ ,
1.1.1.270: zymostenol + NADP+ ← 5α-cholesta-8-en-3-one + NADPH + H+ ,
1.1.1.270: 4α-methyl-zymosterol + NADP+ ← 3-dehydro-4-methylzymosterol + NADPH + H+ ,
1.1.1.270: 4α-methyl-5α-cholest-7-en-3β-ol + NADP+ = 4α-methyl-5α-cholest-7-en-3-one + NADPH + H+ ,
1.1.1.270: 4α-methyl-cholesta-8-enol + NADP+ ← 4α-methyl-5α-cholesta-8-en-3-one + NADPH + H+ ,
1.1.1.271: GDP-β-L-fucose + NADP+ ← GDP-4-dehydro-α-D-rhamnose + NADPH + H+ ,
1.1.1.278: allopregnanolone + NADP+ = 5-α-pregnane-3,20-dione + NADPH + H+ ,
1.1.1.284: S-hydroxymethylglutathione + NAD(P)+S-formylglutathione + NAD(P)H + H+ ,
1.1.1.300: all-trans-retinol + NADP+all-trans-retinal + NADPH + H+ ,
1.1.1.315: an 11-cis-retinol-[retinal-binding protein] + NAD+ → an 11-cis-retinal-[retinal-binding protein] + NADH + H+ ,
1.1.1.330: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain oxoacyl-CoA + NADPH + H+ ,
1.1.1.-: acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
1.1.1.-: 13-cis-retinol + NAD+ → 13-cis-retinal + NADH + H+ ,
1.1.1.-: 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: trans-2-pentenol + NADP+ = trans-2-pentenal + NADPH + H+ ,
1.1.1.-: a (3R)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.-: n-butanol + NAD+ ← butanal + NADH + H+ ,
1.1.1.-: choloyl-CoA + NAD(P)+ = 3-oxo-cholyl-CoA + NAD(P)H + H+ ,
1.1.1.-: 11-cis-retinol + NADP+ = 11-cis-retinal + NADPH + H+ ,
1.1.1.-: (6E)-8-hydroxygeranial + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ,
1.1.1.-: (R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: cholate + NAD+ = 3-dehydrocholate + NADH + H+ ,
1.1.1.-: trans-2-hexenol + NADP+ = trans-2-hexenal + NADPH + H+ ,
1.1.1.-: n-butanol + NADP+ = butanal + NADPH + H+ ,
1.1.1.-: 9-cis-retinol + NAD+ = 9-cis-retinal + NADH + H+ ,
1.1.1.-: (6E)-8-oxogeraniol + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ,
1.1.3.15: an (S)-2-hydroxyacid + oxygen → hydrogen peroxide + a 2-oxo carboxylate ,
1.1.3.-: glycolate + oxygen → glyoxylate + hydrogen peroxide ,
1.1.5.3: sn-glycerol 3-phosphate[mitochondrial intermembrane space] + an ubiquinone[mitochondrial inner membrane] → dihydroxyacetone phosphate[mitochondrial intermembrane space] + an ubiquinol[mitochondrial inner membrane] ,
1.1.5.-: (R)-lactate + an ubiquinone[inner membrane] → pyruvate + an ubiquinol[inner membrane] ,
1.1.99.1: choline + an oxidized electron acceptor → betaine aldehyde + a reduced electron acceptor ,
1.1.99.2: (S)-2-hydroxyglutarate + an oxidized electron acceptor = 2-oxoglutarate + a reduced electron acceptor ,
1.1.99.14: glycolate + an oxidized electron acceptor = glyoxylate + a reduced electron acceptor ,
1.1.99.24: (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate ,
1.1.-.-: allopregnanolone[cytosol] + NAD+[cytosol] → 5-α-pregnane-3,20-dione[cytosol] + NADH[cytosol] + H+[cytosol] ,
1.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O → an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: phytenal + NAD+ + H2O → phytenate + NADH + 2 H+ ,
1.2.1.3: 3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O → 3,4-dihydroxyphenylacetate + NADH + 2 H+ ,
1.2.1.3: 5-hydroxyindole acetaldehyde + NAD+ + H2O → 5-hydroxyindole acetate + NADH + 2 H+ ,
1.2.1.3: a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O → a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+ ,
1.2.1.3: 3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O → 3,4-dihydroxymandelate + NADH + 2 H+ ,
1.2.1.3: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ ,
1.2.1.3: a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+ ,
1.2.1.3: octanal + NAD+ + H2O = octanoate + NADH + 2 H+ ,
1.2.1.3: imidazole acetaldehyde + NAD+ + H2O → 4-imidazoleacetate + NADH + 2 H+ ,
1.2.1.3: 3-methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O → vanillyl mandelate + NADH + 2 H+ ,
1.2.1.3: 4-acetamidobutanal + NAD+ + H2O → 4-acetamidobutanoate + NADH + 2 H+ ,
1.2.1.3: indole acetaldehyde + NAD+ + H2O → indole-3-acetate + NADH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + 2 H+ ,
1.2.1.5: an aldehyde + NAD(P)+ + H2O = a carboxylate + NAD(P)H + 2 H+ ,
1.2.1.5: indole acetaldehyde + NAD(P)+ + H2O = indole-3-acetate + NAD(P)H + 2 H+ ,
1.2.1.8: betaine aldehyde + NAD+ + H2O → glycine betaine + NADH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ → acetyl-CoA + NADH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.18: malonate semialdehyde + coenzyme A + NAD(P)+ → acetyl-CoA + CO2 + NAD(P)H ,
1.2.1.19: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+ ,
1.2.1.22: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+ ,
1.2.1.24: succinate semialdehyde + NAD+ + H2O → succinate + NADH + 2 H+ ,
1.2.1.25: 3-methyl-2-oxobutanoate + coenzyme A + NAD+ → isobutanoyl-CoA + CO2 + NADH ,
1.2.1.27: (S)-methylmalonate-semialdehyde + coenzyme A + NAD+ + H2O → propanoyl-CoA + hydrogen carbonate + NADH + H+ ,
1.2.1.31: (S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O → L-2-aminoadipate + NAD(P)H + 2 H+ ,
1.2.1.32: 2-aminomuconate 6-semialdehyde + NAD+ + H2O → 2-aminomuconate + NADH + 2 H+ ,
1.2.1.36: an all-trans retinal-[cellular-retinol-binding-protein] + NAD+ + H2O → all-trans-retinoate + a cellular-retinol-binding protein + NADH + H+ ,
1.2.1.36: all-trans-retinal + NAD+ + H2O = all-trans-retinoate + NADH + 2 H+ ,
1.2.1.39: phenylacetaldehyde + NAD+ + H2O → phenylacetate + NADH + 2 H+ ,
1.2.1.41: L-glutamate-5-semialdehyde[mitochondrial lumen] + NADP+[mitochondrial lumen] + phosphate[mitochondrial lumen] ← γ-L-glutamyl 5-phosphate[mitochondrial lumen] + NADPH[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.2.1.42: palmitaldehyde + coenzyme A + NAD+ = palmitoyl-CoA + NADH + H+ ,
1.2.1.47: 4-trimethylammoniobutanal + NAD+ + H2O → γ-butyrobetaine + NADH + 2 H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.84: a long-chain acyl-CoA + 2 NADPH + 2 H+ = a long-chain alcohol + coenzyme A + 2 NADP+ ,
1.2.1.88: L-glutamate-5-semialdehyde + NAD+ + H2O → L-glutamate + NADH + 2 H+ ,
1.2.1.-: (S)-3-methyl-2-oxopentanoate + coenzyme A + NAD+ → 2-methylbutanoyl-CoA + CO2 + NADH ,
1.2.1.-: 4-methyl-2-oxopentanoate + coenzyme A + NAD+ → isovaleryl-CoA + CO2 + NADH ,
1.2.1.-: pyruvate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + NAD+[mitochondrial lumen] = acetyl-CoA[mitochondrial lumen] + CO2[mitochondrial lumen] + NADH[mitochondrial lumen] ,
1.2.1.-: (S)-lactaldehyde + NADP+ + H2O = (S)-lactate + NADPH + 2 H+ ,
1.2.1.-: (S)-2-amino-6-oxohexanoate + NAD+ + H2O = L-2-aminoadipate + NADH + 2 H+ ,
1.2.1.-: L-4-hydroxyglutamate semialdehyde + NAD+ + H2O → erythro-4-hydroxy-L-glutamate + NADH + 2 H+ ,
1.2.1.-: malonate semialdehyde + coenzyme A + NAD+ = acetyl-CoA + CO2 + NADH ,
1.2.1.-: (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD+ + 2 H2O = L-2-aminoadipate + NADH + H+ ,
1.2.1.-: apo-4'-lycopenal + NAD(P)+ + H2O = apo-4'-lycopenoate + NADPH + H+ ,
1.2.1.-: malonate semialdehyde + coenzyme A + NADP+ = acetyl-CoA + CO2 + NADPH ,
1.2.3.1: acetaldehyde + oxygen + H2O → acetate + hydrogen peroxide + H+ ,
1.2.3.1: heptanal + oxygen + H2O → heptanoate + hydrogen peroxide + H+ ,
1.2.3.1: all-trans-retinal + H2O + oxygen → all-trans-retinoate + hydrogen peroxide + H+ ,
1.2.3.1: geranial + oxygen + H2O → geranate + hydrogen peroxide + H+ ,
1.2.3.1: an aldehyde + oxygen + H2O → a carboxylate + hydrogen peroxide + H+ ,
1.2.3.-: nicotine-Δ1'5'-iminium ion + oxygen + H2O → cotinine + hydrogen peroxide + H+ ,
1.2.99.7: an aldehyde + FAD + H2O = a carboxylate + FADH2 ,
1.3.1.2: 5,6-dihydrouracil + NADP+ ← uracil + NADPH + H+ ,
1.3.1.2: 5,6-dihydrothymine + NADP+ ← thymine + NADPH + H+ ,
1.3.1.3: 5β-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ ,
1.3.1.3: 7α-hydroxycholest-4-en-3-one + NADPH + H+ → 7α-hydroxy-5β-cholestan-3-one + NADP+ ,
1.3.1.3: 4,5β-dihydrocortisone + NADP+ = cortisone + NADPH + H+ ,
1.3.1.3: 7α,12α-dihydroxycholest-4-en-3-one + NADPH + H+ → 7α,12α-dihydroxy-5β-cholestan-3-one + NADP+ ,
1.3.1.14: (S)-dihydroorotate + NAD+ = orotate + NADH + H+ ,
1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+ ,
1.3.1.21: cholesterol + NADP+ ← 7-dehydrocholesterol + NADPH + H+ ,
1.3.1.21: desmosterol + NADP+ ← 7-dehydrodesmosterol + NADPH + H+ ,
1.3.1.22: 4,5α-dihydrocortisone + NADP+ = cortisone + NADPH + H+ ,
1.3.1.22: a 3-oxo-5-α-steroid + NADP+ = a 3-oxo-Δ4-steroid + NADPH + H+ ,
1.3.1.22: 5-α-dihydrotestosterone + NADP+ ← testosterone + NADPH + H+ ,
1.3.1.22: 5α-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ ,
1.3.1.22: 5-α-pregnane-3,20-dione + NADP+ ← progesterone + NADPH + H+ ,
1.3.1.24: bilirubin + NAD(P)+ ← biliverdin-IX-α + NAD(P)H + H+ ,
1.3.1.27: palmitaldehyde + NADP+ ← 2-trans-hexadecenal + NADPH + H+ ,
1.3.1.34: trans-Δ2-decenoyl-CoA + NADP+ = trans-Δ2, cis-Δ4-decadienoyl-CoA + NADPH + H+ ,
1.3.1.34: a 2-trans-4-cis-dienoyl-CoA + NADPH = a trans-3-enoyl-CoA + NADP+ + H+ ,
1.3.1.38: phytenoyl-CoA + NADPH + H+ → phytanoyl-CoA + NADP+ ,
1.3.1.38: a 2,3,4-saturated fatty acyl CoA + NADP+ = a trans-2-enoyl-CoA + NADPH + H+ ,
1.3.1.48: (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+ ,
1.3.1.70: 4,4-dimethylzymosterol + NADP+ ← 14-demethyllanosterol + NADPH + H+ ,
1.3.1.70: 4α-methyl-5α-ergosta-8,24-dien-3β-ol + NADP+ = 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + NADPH + H+ ,
1.3.1.70: 4,4-dimethyl-5α-cholesta-8-en-3-β-ol + NADP+ ← 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + NADPH + H+ ,
1.3.1.72: desmosterol + NADPH + H+ → cholesterol + NADP+ ,
1.3.1.72: lanosterol + NADPH + H+ → 24,25-dihydrolanosterol + NADP+ ,
1.3.1.72: lathosterol + NADP+ ← 5α-cholesta-7,24-dien-3β-ol + NADPH + H+ ,
1.3.1.93: a very-long-chain 2,3,4-saturated fatty acyl CoA + NADP+ = a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ ,
1.3.1.94: a ditrans,polycis-dolichol + NADP+ = a di-trans, poly-cis-polyprenol + NADPH + H+ ,
1.3.1.96: squalene + NADP+ + diphosphate = presqualene diphosphate + NADPH + H+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.3.6: a 2,3,4-saturated fatty acyl CoA + oxygen → a trans-2-enoyl-CoA + hydrogen peroxide ,
1.3.3.6: an acyl-CoA + oxygen → a trans-2-enoyl-CoA + hydrogen peroxide ,
1.3.5.1: succinate[mitochondrial lumen] + an ubiquinone[mitochondrial inner membrane] → fumarate[mitochondrial lumen] + an ubiquinol[mitochondrial inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an electron-transfer-related quinone[inner membrane] → orotate + an electron-transfer-related quinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an ubiquinone[inner membrane] → orotate + an ubiquinol[inner membrane] ,
1.3.8.4: isovaleryl-CoA + an oxidized electron-transfer flavoprotein → 3-methylcrotonyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.5: 2-methylbutanoyl-CoA + an oxidized electron-transfer flavoprotein → (E)-2-methylcrotonoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.6: glutaryl-CoA + an oxidized electron-transfer flavoprotein = crotonyl-CoA + CO2 + a reduced electron-transfer flavoprotein ,
1.3.8.7: a medium-chain 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein = a medium-chain trans-2,3-dehydroacyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.7: decanoyl-CoA + an oxidized electron-transfer flavoprotein = trans-Δ2-decenoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.8: a long-chain 2,3,4-saturated fatty acyl CoA[mitochondrial lumen] + an oxidized electron-transfer flavoprotein[mitochondrial lumen] = a long-chain trans-2,3-dehydroacyl-CoA[mitochondrial lumen] + a reduced electron-transfer flavoprotein[mitochondrial lumen] ,
1.3.8.-: isobutanoyl-CoA + FAD + H+ → methylacrylyl-CoA + FADH2 ,
1.3.8.-: a 2,3,4-saturated fatty acyl CoA[mitochondrial lumen] + an oxidized electron-transfer flavoprotein[mitochondrial lumen] + H+[mitochondrial lumen] → a trans-2-enoyl-CoA[mitochondrial lumen] + a reduced electron-transfer flavoprotein[mitochondrial lumen] ,
1.3.98.1: (S)-dihydroorotate + fumarate → orotate + succinate ,
1.3.99.6: a 3-oxo-5-β-steroid + an oxidized electron acceptor = a 3-oxo-Δ4-steroid + a reduced electron acceptor ,
1.3.99.12: 2-methylbutanoyl-CoA + an oxidized electron acceptor = (E)-2-methylcrotonoyl-CoA + a reduced electron acceptor ,
1.3.99.23: all-trans-13,14-dihydroretinol + an oxidized electron acceptor = all-trans-retinol + a reduced electron acceptor ,
1.3.99.-: pseudooxynicotine + oxygen + 2 H2O → 4-oxo-4-(3-pyridyl)-butanoate + methylamine + hydrogen peroxide ,
1.4.1.2: L-glutamate[mitochondrial lumen] + NAD+[mitochondrial lumen] + H2O[mitochondrial lumen] = 2-oxoglutarate[mitochondrial lumen] + ammonium[mitochondrial lumen] + NADH[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.4.1.3: L-glutamate[mitochondrial lumen] + NAD(P)+[mitochondrial lumen] + H2O[mitochondrial lumen] ↔ 2-oxoglutarate[mitochondrial lumen] + ammonium[mitochondrial lumen] + NAD(P)H[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.4.1.21: L-aspartate + NAD(P)+ + H2O = oxaloacetate + ammonium + NAD(P)H + H+ ,
1.4.3.2: L-arginine + oxygen + H2O → ammonium + 2-ketoarginine + hydrogen peroxide ,
1.4.3.2: a standard α amino acid + oxygen + H2O → ammonium + hydrogen peroxide + a 2-oxo carboxylate ,
1.4.3.3: a D-amino acid + oxygen + H2O → ammonium + hydrogen peroxide + a 2-oxo carboxylate ,
1.4.3.4: 2-phenylethylamine + oxygen + H2O → phenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: metanephrine + H2O + oxygen → 3-methoxy-4-hydroxyphenylglycolaldehyde + methylamine + hydrogen peroxide ,
1.4.3.4: N-acetylputrescine + H2O + oxygen → 4-acetamidobutanal + ammonium + hydrogen peroxide ,
1.4.3.4: dopamine + H2O + oxygen → 3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: a monoamine + H2O + oxygen → an aldehyde + a primary amine + hydrogen peroxide ,
1.4.3.4: 5-methoxytryptamine + H+ + H2O + oxygen → 5-methoxyindoleacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: (R)-adrenaline + H2O + oxygen → 3,4-dihydroxyphenylglycolaldehyde + methylamine + hydrogen peroxide ,
1.4.3.4: serotonin + oxygen + H2O → 5-hydroxyindole acetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: (R)-noradrenaline + H2O + oxygen → 3,4-dihydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: tryptamine + H2O + oxygen → ammonium + indole acetaldehyde + hydrogen peroxide ,
1.4.3.4: normetanephrine + H2O + oxygen → 3-methoxy-4-hydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.5: pyridoxamine 5'-phosphate + oxygen + H2O → ammonium + hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.13: a [protein]-L-lysine + oxygen + H2O → a protein L-allysine + ammonium + hydrogen peroxide ,
1.4.3.21: cadaverine + H2O + oxygen → 5-aminopentanal + ammonium + hydrogen peroxide ,
1.4.3.21: aminoacetone + H2O + oxygen → methylglyoxal + ammonium + hydrogen peroxide ,
1.4.3.21: 2-phenylethylamine + oxygen + H2O → phenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.21: an aliphatic amine + H2O + oxygen → an aldehyde + ammonium + hydrogen peroxide ,
1.4.3.21: a primary amine + H2O + oxygen → an aldehyde + ammonium + hydrogen peroxide ,
1.4.3.22: a diamine + H2O + oxygen → a monoamine + ammonium + hydrogen peroxide ,
1.4.3.22: histamine + H2O + oxygen → imidazole acetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.-: L-tryptophan + oxygen → 2-imino-3-(indol-3-yl)propanoate + hydrogen peroxide + H+ ,
1.5.1.2: trans-4-hydroxy-L-proline + NAD(P)+ ← (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: a tetrahydrofolate + NADP+ ← a 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: a 5,10-methylene-tetrahydrofolate + NADP+ ↔ a 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.6: an N10-formyl-tetrahydrofolate + NADP+ + H2O = a tetrahydrofolate + CO2 + NADPH + H+ ,
1.5.1.8: L-saccharopine + NADP+ + H2O ← 2-oxoglutarate + L-lysine + NADPH + H+ ,
1.5.1.9: L-saccharopine + NAD+ + H2O → L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+ ,
1.5.1.15: a 5,10-methylene-tetrahydrofolate + NAD+ → a 5,10-methenyltetrahydrofolate + NADH ,
1.5.1.20: an N5-methyl-tetrahydrofolate + NAD+ ← a 5,10-methylene-tetrahydrofolate + NADH + H+ ,
1.5.1.21: L-pipecolate + NADP+ ← (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NADPH + 2 H+ ,
1.5.1.21: L-pipecolate + NAD(P)+ ← Δ1-piperideine-2-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.25: thiomorpholine-3-carboxylate + NAD(P)+ = 3,4-dehydrothiomorpholine-3-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.27: (R)-reticuline + NADP+ ← 1,2-dehydroreticulinium + NADPH + H+ ,
1.5.1.30: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+ ,
1.5.1.34: a 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H+ ,
1.5.1.38: NADP+ + FMNH2 = NADPH + FMN + 2 H+ ,
1.5.1.39: FMNH2 + NAD(P)+ = FMN + NAD(P)H + 2 H+ ,
1.5.1.-: L-erythro-5,6,7,8-tetrahydrobiopterin + NAD+ ← L-erythro-7,8-dihydrobiopterin + NADH + H+ ,
1.5.1.-: tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ ,
1.5.3.1: sarcosine + oxygen + H2O → hydrogen peroxide + formaldehyde + glycine ,
1.5.3.7: L-pipecolate + oxygen → (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + hydrogen peroxide + H+ ,
1.5.3.13/1.5.3.17: N1-acetylspermidine + oxygen + H2O → putrescine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.13: N1,N12-diacetylspermine + oxygen + H2O → N1-acetylspermidine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.13: N1-acetylspermine + oxygen + H2O → spermidine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.14: spermine + oxygen + H2O → 1-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide ,
1.5.3.16: norspermine + oxygen + H2O → norspermidine + 3-aminopropanal + hydrogen peroxide ,
1.5.3.16: N1-acetylspermine + oxygen + H2O → hydrogen peroxide + 3-aminopropanal + N1-acetylspermidine ,
1.5.3.17: spermine + H2O + oxygen → 3-aminopropanal + spermidine + hydrogen peroxide ,
1.5.5.2: L-proline[in] + an ubiquinone[in] → (S)-1-pyrroline-5-carboxylate[in] + an ubiquinol[in] + H+[in] ,
1.5.5.2: L-proline[in] + an electron-transfer-related quinone → (S)-1-pyrroline-5-carboxylate[in] + an electron-transfer-related quinol + H+[in] ,
1.5.5.2: L-proline[in] + an ubiquinone[in] → (S)-1-pyrroline-5-carboxylate[in] + an ubiquinol[in] + H+[in] ,
1.5.5.-: trans-4-hydroxy-L-proline[in] + an electron-transfer-related quinone → (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate[in] + an electron-transfer-related quinol + H+[in] ,
1.5.8.3: sarcosine + an oxidized electron-transfer flavoprotein + H2O + H+ = glycine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.8.4: dimethylglycine + an oxidized electron-transfer flavoprotein + H2O + H+ = sarcosine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.8.-: dimethylglycine + an oxidized electron-transfer flavoprotein + a tetrahydrofolate → sarcosine + a 5,10-methenyltetrahydrofolate + a reduced electron-transfer flavoprotein ,
1.5.8.-: (S)-nicotine + an oxidized flavoprotein → nicotine-Δ1'5'-iminium ion + a reduced flavoprotein ,
1.5.8.-: sarcosine + an oxidized electron-transfer flavoprotein + a tetrahydrofolate → glycine + a 5,10-methenyltetrahydrofolate + a reduced electron-transfer flavoprotein ,
1.6.1.2/1.6.1.3: NADPH + NAD+ = NADH + NADP+ ,
1.6.1.2: NADH + NADP+ + H+[out] → NADPH + NAD+ + H+[in] ,
1.6.3.1: NAD(P)H + H+ + oxygen → hydrogen peroxide + NAD(P)+ ,
1.6.5.2: a quinone + NAD(P)H + H+ → a quinol + NAD(P)+ ,
1.6.5.2: a plastoquinone + NAD(P)H + H+ ↔ a plastoquinol + NAD(P)+ ,
1.6.5.3: NADH[mitochondrial lumen] + an ubiquinone[mitochondrial inner membrane] + 5 H+[mitochondrial lumen] ↔ NAD+[mitochondrial lumen] + an ubiquinol[mitochondrial inner membrane] + 4 H+[mitochondrial intermembrane space] ,
1.6.5.4: 2 monodehydroascorbate radical + NADH → 2 L-ascorbate + NAD+ + H+ ,
1.6.5.5: a quinone + NADPH = a semiquinone + NADP+ ,
1.6.5.9: NADH + an ubiquinone[inner membrane] + H+ → NAD+ + an ubiquinol[inner membrane] ,
1.6.5.10: NADPH + an electron-transfer-related quinone + H+ = NADP+ + an electron-transfer-related quinol ,
1.6.5.-: 2 monodehydroascorbate radical + NADPH + H+ → 2 L-ascorbate + NADP+ + 2 H+ ,
1.6.99.3: NADH + an oxidized electron acceptor + H+ = NAD+ + a reduced electron acceptor ,
1.7.1.7: ammonium + IMP + NADP+ = GMP + NADPH + 2 H+ ,
1.8.1.3: hypotaurine + NAD+ + H2O → taurine + NADH + H+ ,
1.8.1.7: 2 glutathione + NADP+ ← glutathione disulfide + NADPH + H+ ,
1.8.1.8: a protein dithiol + NAD(P)+ = a protein disulfide + NAD(P)H + H+ ,
1.8.3.1: sulfite + oxygen + H2O → hydrogen peroxide + sulfate ,
1.8.3.2: 2 R'C(R)SH + oxygen → R'C(R)S-S(R)CR' + hydrogen peroxide ,
1.8.3.5: S-prenyl-L-cysteine + H2O + oxygen → 3-methyl-2-butenal + hydrogen peroxide + L-cysteine ,
1.8.3.6: S-(2E,6E)-farnesyl-L-cysteine + oxygen + H2O → (2E,6E)-farnesal + L-cysteine + hydrogen peroxide ,
1.8.4.2: 2 glutathione + a protein disulfide = glutathione disulfide + a protein dithiol ,
1.8.5.1: L-dehydro-ascorbate + 2 glutathione → L-ascorbate + glutathione disulfide + H+ ,
1.8.5.4: hydrogen sulfide + an electron-transfer-related quinone = intracellular S0 + an electron-transfer-related quinol ,
1.8.98.2: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + a protein dithiol = peroxiredoxin-(S-hydroxycysteine) + ADP + a protein disulfide + phosphate + H+ ,
1.9.3.1/1.10.2.2: 2 an ubiquinol[mitochondrial inner membrane] + oxygen[mitochondrial lumen] + 12 H+[mitochondrial lumen] → 2 an ubiquinone[mitochondrial inner membrane] + 2 H2O[mitochondrial lumen] + 12 H+[mitochondrial intermembrane space] ,
1.10.3.1: 2 cis-caffeate + oxygen → 2 3-(2-propenoic acid)-o-benzoquinone + 2 H2O ,
1.10.3.1: 2 catechol + oxygen → 2 1,2-benzoquinone + 2 H2O ,
1.10.3.-: L-dopa + 0.5 oxygen → dopaquinone + H2O ,
1.10.99.2: 1-(β-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H+ = a quinol + 1-(β-D ribofuranosyl)nicotinamide ,
1.11.1.6: ethanol + hydrogen peroxide → acetaldehyde + 2 H2O ,
1.11.1.7: a phenolic donor + hydrogen peroxide = 2 a phenoxyl radical of a phenolic donor + 2 H2O ,
1.11.1.7: 2 betanidin + hydrogen peroxide = betanidin + betanidin quinone + 2 H2O ,
1.11.1.8: [thyroglobulin]-3-iodotyrosine + [thyroglobulin]-3,5-diiodotyrosine + hydrogen peroxide → [thyroglobulin]-triiodothyronine + [thyroglobulin]-aminoacrylate + 2 H2O ,
1.11.1.8: [thyroglobulin]-3-iodotyrosine + iodide + hydrogen peroxide + H+ → [thyroglobulin]-3,5-diiodotyrosine + 2 H2O ,
1.11.1.8: hydrogen peroxide + 2 iodide + 2 H+ = I2 + 2 H2O ,
1.11.1.8: [thyroglobulin]-L-tyrosine + hydrogen peroxide + iodide + H+ → [thyroglobulin]-3-iodotyrosine + 2 H2O ,
1.11.1.8: 2 [thyroglobulin]-3,5-diiodotyrosine + hydrogen peroxide → [thyroglobulin]-L-thyroxine + [thyroglobulin]-aminoacrylate + 2 H2O ,
1.11.1.9: hydrogen peroxide + 2 glutathione → glutathione disulfide + 2 H2O ,
1.11.1.11: 2 L-ascorbate + hydrogen peroxide + H+ → L-ascorbate + L-dehydro-ascorbate + 2 H2O ,
1.11.1.12: a lipid hydroperoxide + 2 glutathione + H+ → a lipid + glutathione disulfide + 2 H2O ,
1.11.1.15: 2 protein cysteines + an organic hydroperoxide = a protein disulfide + an alcohol + H2O ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.11.2.2: chloride + hydrogen peroxide + H+ = hypochlorous acid + H2O ,
1.13.11.5: homogentisate + oxygen → 4-maleyl-acetoacetate + H+ ,
1.13.11.6: 3-hydroxyanthranilate + oxygen → aminocarboxymuconate semialdehyde + H+ ,
1.13.11.11/1.13.11.52: L-tryptophan + oxygen → N-formylkynurenine ,
1.13.11.19: cysteamine + oxygen → hypotaurine + H+ ,
1.13.11.20: L-cysteine + oxygen → 3-sulfinoalanine + H+ ,
1.13.11.27: 2-oxo-3-phenylpropanoate + oxygen → 2-hydroxyphenylacetate + CO2 ,
1.13.11.27: 4-hydroxyphenylpyruvate + oxygen → CO2 + homogentisate ,
1.13.11.31: arachidonate + oxygen → (12S)-HPETE ,
1.13.11.33: arachidonate + oxygen → (15S)-HPETE ,
1.13.11.34: arachidonate + oxygen → leukotriene A4 + H2O ,
1.13.11.52: D-tryptophan + oxygen → N-formyl-D-kynurenine ,
1.13.11.54: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 2-oxo-4-methylthiobutanoate + formate + H+ ,
1.13.11.63: all-trans-β-carotene + oxygen → 2 all-trans-retinal ,
1.13.11.71: all-trans-β-carotene + oxygen → all-trans-10'-apo-β-carotenal + β-ionone ,
1.13.11.-: all-trans-10'-apo-β-carotenal + oxygen → β-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaene-1,12-dial ,
1.13.11.-: 4-methyl-2-oxopentanoate + oxygen → 3-hydroxyisovalerate + CO2 ,
1.13.11.-: leukotriene A4 + a reduced electron acceptor + oxygen → lipoxin B4 + an oxidized electron acceptor ,
1.13.11.-: leukotriene A4 + a reduced electron acceptor + oxygen → lipoxin A4 + an oxidized electron acceptor ,
1.13.11.-: all-trans-β-carotene + 2 oxygen → 2 β-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaene-1,12-dial ,
1.13.99.1: myo-inositol + oxygen → D-glucopyranuronate + H+ + H2O ,
1.14.11.1: 2-oxoglutarate + γ-butyrobetaine + oxygen → L-carnitine + CO2 + succinate ,
1.14.11.2: a [procollagen]-L-proline + 2-oxoglutarate + oxygen → a [procollagen] trans 4-hyroxy-L-proline + CO2 + succinate ,
1.14.11.4: a [procollagen]-L-lysine + 2-oxoglutarate + oxygen → a [procollagen]-5-hydroxy-L-lysine + CO2 + succinate ,
1.14.11.7: a [procollagen]-L-proline + 2-oxoglutarate + oxygen → a [procollagen]-3-hydroxy-L-proline + CO2 + succinate ,
1.14.11.8: 2-oxoglutarate + N6,N6,N6-trimethyl-L-lysine + oxygen → CO2 + succinate + 3-hydroxy-N6,N6,N6-trimethyl-L-lysine ,
1.14.11.16: a [protein]-L-aspartate + 2-oxoglutarate + oxygen → CO2 + succinate + a [protein]-3-hydroxy-L-aspartate ,
1.14.11.18: 2-oxoglutarate + phytanoyl-CoA + oxygen → CO2 + succinate + 2-hydroxyphytanoyl-CoA ,
1.14.11.31: thebaine + 2-oxoglutarate + oxygen → neopinone + formaldehyde + succinate + CO2 ,
1.14.11.31: oripavine + 2-oxoglutarate + oxygen → morphinone + formaldehyde + succinate + CO2 ,
1.14.11.32: thebaine + 2-oxoglutarate + oxygen → oripavine + formaldehyde + succinate + CO2 ,
1.14.11.32: codeine + 2-oxoglutarate + oxygen → morphine + formaldehyde + succinate + CO2 ,
1.14.11.33: N1-methyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + formaldehyde + succinate ,
1.14.11.33: a methylated nucleobase within DNA + 2-oxoglutarate + oxygen → a nucleobase within DNA + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: 1-ethyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + acetaldehyde + succinate ,
1.14.11.33: N3-methylcytosine + 2-oxoglutarate + oxygen → cytosine + CO2 + formaldehyde + succinate + H+ ,
1.14.11.42: 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + 2-oxoglutarate + oxygen → 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe + succinate + CO2 ,
1.14.11.-: a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + 2-oxoglutarate + oxygen → a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA + succinate + CO2 ,
1.14.11.-: a [protein] N6-methyl-L-lysine + 2-oxoglutarate + oxygen + H+ → a [protein]-L-lysine + succinate + formaldehyde + CO2 ,
1.14.13.8: N,N-dimethylaniline + NADPH + oxygen + H+N,N-dimethylaniline-N-oxide + NADP+ + H2O ,
1.14.13.8: (S)-nicotine + NADPH + oxygen → nicotine-1'-N-oxide + NADP+ + H2O ,
1.14.13.9: L-kynurenine + NADPH + oxygen + H+ → 3-hydroxy-L-kynurenine + NADP+ + H2O ,
1.14.13.13: calcidiol + NADPH + H+ + oxygen → calcitriol + NADP+ + H2O ,
1.14.13.15: 5β-cholestane-3α,7α,12α-triol + 3 NADPH + 2 H+ + 3 oxygen → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + 3 NADP+ + 4 H2O ,
1.14.13.15: 5β-cholestane-3α,7α-diol + 3 NADPH + 2 H+ + 3 oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + 3 NADP+ + 4 H2O ,
1.14.13.17: cholesterol + NADPH + H+ + oxygen → 7α-hydroxycholesterol + NADP+ + H2O ,
1.14.13.30: leukotriene B4 + NADPH + oxygen + H+ → 20-hydroxy-leukotriene B4 + NADP+ + H2O ,
1.14.13.30: α-tocopherol + NADPH + oxygen + H+ → 13'-hydroxy-α-tocopherol + NADP+ + H2O ,
1.14.13.32: albendazole + NADPH + H+ + oxygen → albendazole s-oxide + NADP+ + H2O ,
1.14.13.39: 2 L-arginine + 3 NADPH + H+ + 4 oxygen → 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O ,
1.14.13.48: (4S)-limonene + NADPH + oxygen + H+ → (-)-trans-carveol + NADP+ + H2O ,
1.14.13.49: (4S)-limonene + NADPH + oxygen + H+ → (4S)-perillyl alcohol + NADP+ + H2O ,
1.14.13.67: quinine + NADPH + H+ + oxygen → 3-hydroxyquinine + NADP+ + H2O ,
1.14.13.70: obtusifoliol + 3 NADPH + 3 oxygen + 2 H+ → formate + 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + 3 NADP+ + 4 H2O ,
1.14.13.70: 4α,14α-dimethyl-5α-cholesta-8,24-dien-3β-ol + 3 NADPH + 3 oxygen + 2 H+ → 4α-methyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 NADP+ + 4 H2O ,
1.14.13.70: 24,25-dihydrolanosterol + 3 NADPH + 3 oxygen + 2 H+ → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate + 3 NADP+ + 4 H2O ,
1.14.13.70: lanosterol + 3 NADPH + 3 oxygen + 2 H+ → 14-demethyllanosterol + formate + 3 NADP+ + 4 H2O ,
1.14.13.72: 4α-methyl-zymosterol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethylzymosterol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethyl-5α-cholesta-8-en-3-β-ol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethyl-5α-cholest-7-en-3β-ol + 3 NAD(P)H + 3 oxygen + 2 H+ → 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4α-methyl-cholesta-8-enol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-5α-cholesta-8-en-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.80: (4R)-limonene + NADPH + H+ + oxygen → (+)-trans-carveol + NADP+ + H2O ,
1.14.13.95: 7α-hydroxycholest-4-en-3-one + NADPH + H+ + oxygen → 7α,12α-dihydroxycholest-4-en-3-one + NADP+ + H2O ,
1.14.13.97: lithocholate + NADPH + H+ + oxygen → hyodeoxycholate + NADP+ + H2O ,
1.14.13.97: taurochenodeoxycholate + NADPH + H+ + oxygen → taurohyocholate + NADP+ + H2O ,
1.14.13.98: cholesterol + NADPH + H+ + oxygen → (24S)-24-hydroxycholesterol + NADP+ + H2O ,
1.14.13.99: (24R)-cholest-5-ene-3β,24-diol + NADPH + H+ + oxygen → (24R)-cholest-5-ene-3β,7α,24-triol + NADP+ + H2O ,
1.14.13.100: cholest-5-ene-3β,25-diol + NADPH + H+ + oxygen → cholest-5-ene-3β,7α,25-triol + NADP+ + H2O ,
1.14.13.100: (25R)-cholest-5-ene-3β,26-diol + NADPH + H+ + oxygen → (25R)-cholest-5-ene-3β,7α,26-triol + NADP+ + H2O ,
1.14.13.126: calcitriol + NADPH + H+ + oxygen → calcitetrol + NADP+ + H2O ,
1.14.13.126: calcidiol + NADPH + H+ + oxygen → secalciferol + NADP+ + H2O ,
1.14.13.132: squalene + NADPH + oxygen + H+ → (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O ,
1.14.13.148: trimethylamine + NADPH + oxygen → trimethylamine N-oxide + NADP+ + H2O ,
1.14.13.159: vitamin D3 + NADPH + H+ + oxygen → calcidiol + NADP+ + H2O ,
1.14.13.-: oleate + NADPH + oxygen + H+ → 18-hydroxyoleate + NADP+ + H2O ,
1.14.13.-: 7-dehydrocholesterol + NADPH + H+ + oxygen → 7-ketocholesterol + NADP+ + H2O ,
1.14.13.-: 2-methoxy-6-(all-trans-decaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
1.14.13.-: indole + NADH + oxygen + H+ → indoxyl + NAD+ + H2O ,
1.14.13.-: 17-α-hydroxyprogesterone + NADPH + H+ + oxygen → 11-desoxycortisol + NADP+ + H2O ,
1.14.13.-: (4S)-limonene + NADPH + oxygen + H+ → (-)-cis-carveol + NADP+ + H2O ,
1.14.13.-: 3-decaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + NADP+ + H2O ,
1.14.13.-: progesterone + NADPH + H+ + oxygen → 11-deoxycorticosterone + NADP+ + H2O ,
1.14.14.1: melatonin + a reduced flavoprotein + oxygen → N-acetyl-serotonin + an oxidized flavoprotein + formaldehyde + H2O ,
1.14.14.1: 4-hydroxybenzaldehyde + a reduced flavoprotein + oxygen → protocatechualdehyde + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → trans-3'-hydroxycotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: (S)-nicotine + a reduced flavoprotein + oxygen → 2'-hydroxynicotine + an oxidized flavoprotein + H2O ,
1.14.14.1: melatonin + a reduced flavoprotein + oxygen → 6-hydroxymelatonin + an oxidized flavoprotein + H2O ,
1.14.14.1: bupropion + a reduced flavoprotein + oxygen → hydroxybupropion + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → 5'-hydroxycotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → N'-hydroxymethyl-norcotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: acetone + a reduced flavoprotein + oxygen → acetol + an oxidized flavoprotein + H2O ,
1.14.14.-: N'-hydroxymethyl-norcotinine + a reduced flavoprotein + oxygen → norcotinine + an oxidized flavoprotein + H2O ,
1.14.15.4: 11-desoxycortisol + 2 a reduced adrenodoxin + oxygen + 2 H+ → cortisol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.4: 11-deoxycorticosterone + 2 a reduced adrenodoxin + oxygen + 2 H+ → corticosterone + 2 an oxidized adrenodoxin + H2O ,
1.14.15.5: 18-hydroxycorticosterone + 2 a reduced adrenodoxin + 2 H+ + oxygen → aldosterone + 2 an oxidized adrenodoxin + 2 H2O ,
1.14.15.5: corticosterone + 2 a reduced adrenodoxin + oxygen + 2 H+ → 18-hydroxycorticosterone + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: (22R)-hydroxycholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → (20R,22R)-dihydroxycholesterol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: cholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → (22R)-hydroxycholesterol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: (20R,22R)-dihydroxycholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → pregnenolone + 4-methylpentanal + 2 an oxidized adrenodoxin + 2 H2O ,
1.14.16.1: L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + oxygen = L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.14.16.1: tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.14.16.2: tetrahydrobiopterin + L-tyrosine + oxygen → 4α-hydroxy-tetrahydrobiopterin + L-dopa ,
1.14.16.4: tetrahydrobiopterin + L-tryptophan + oxygen → 5-hydroxy-L-tryptophan + 4α-hydroxy-tetrahydrobiopterin ,
1.14.17.1: dopamine + L-ascorbate + H+ + oxygen → L-dehydro-ascorbate + (R)-noradrenaline + H2O ,
1.14.17.3: a C-terminal [protein]-glycine + L-ascorbate + oxygen → a C-terminal [protein]-hydroxyglycine + L-dehydro-ascorbate + H2O ,
1.14.18.1: L-tyrosine + oxygen → dopaquinone + H2O ,
1.14.19.3: linoleoyl-CoA + a reduced electron acceptor + oxygen → γ-linolenoyl-CoA + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: eicosatetraenoyl-CoA + a reduced electron acceptor + oxygen → eicosapentaenoyl-CoA + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: α-linolenoyl-CoA + a reduced electron acceptor + oxygen → stearidonoyl-CoA + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: linoleate + a reduced electron acceptor + oxygen → γ-linolenate + an oxidized electron acceptor + 2 H2O ,
1.14.19.-: oleate + a reduced electron acceptor + oxygen → linoleate + an oxidized electron acceptor + 2 H2O ,
1.14.21.4: (R)-reticuline + NADPH + H+ + oxygen → salutaridine + NADP+ + 2 H2O ,
1.14.21.6: 5α-cholesta-7,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 7-dehydrodesmosterol + NAD(P)+ + 2 H2O ,
1.14.21.6: lathosterol + NAD(P)H + oxygen + H+ → 7-dehydrocholesterol + NAD(P)+ + 2 H2O ,
1.14.99.1: arachidonate + a reduced electron acceptor + 2 oxygen → prostaglandin-H2 + an oxidized electron acceptor + H2O ,
1.14.99.3: ferroheme b + 3 a reduced electron acceptor + 3 oxygen + 2 H+ → carbon monoxide + Fe2+ + biliverdin-IX-α + 3 an oxidized electron acceptor + 3 H2O ,
1.14.99.9: pregnenolone + NADPH + H+ + oxygen → 17-α-hydroxypregnenolone + NADP+ + H2O ,
1.14.99.9: a C21-steroid + a reduced electron acceptor + oxygen → a 17α-hydroxy-C21-steroid + an oxidized electron acceptor + H2O ,
1.14.99.9: progesterone + NADPH + oxygen + H+ → 17-α-hydroxyprogesterone + NADP+ + H2O ,
1.14.99.10: a C21-steroid + a reduced [NADPH-hemoprotein reductase] + oxygen → a 21-hydroxy-C21-steroid + an oxidized [NADPH-hemoprotein reductase] + H2O ,
1.14.99.36: all-trans-β-carotene + oxygen → 2 all-trans-retinal ,
1.14.99.38: cholesterol + a reduced electron acceptor + oxygen → cholest-5-ene-3β,25-diol + an oxidized electron acceptor + H2O ,
1.14.-.-: 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen → 3-demethylubiquinol-10 + an oxidized electron acceptor + H2O ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.16.1.7: 2 an Fe(II)-siderophore + NAD+ + H+ ← 2 an Fe(III)-siderophore + NADH ,
1.16.3.1: 4 Fe2+ + 4 H+ + oxygen → 4 Fe3+ + 2 H2O ,
1.16.5.1: L-ascorbate[in] + Fe3+[out] ↔ monodehydroascorbate radical[in] + Fe2+[out] ,
1.16.5.1: L-ascorbate[in] + Fe3+[out] → monodehydroascorbate radical[in] + Fe2+[out] ,
1.17.1.4: hypoxanthine + NAD+ + H2O → xanthine + NADH + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.1.-: an all-trans retinol-[cellular-retinol-binding-protein] + NAD+ + H2O → all-trans-retinoate + NADH + H+ ,
1.17.3.2: an organic molecule + H2O + 2 oxygen → an alcohol + 2 superoxide + 2 H+ ,
1.17.3.2: xanthine + oxygen + H2O → hydrogen peroxide + urate ,
1.17.4.-: phylloquinone + oxidized dithiothreitol + H2O = dithiothreitol + vitamin K 2,3-epoxide ,
1.17.7.2: 71-hydroxychlorophyll a + 2 a reduced ferredoxin + 2 H+ = chlorophyll a + 2 an oxidized ferredoxin + H2O ,
1.17.99.3: (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an oxidized electron acceptor + H2O = (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + a reduced electron acceptor ,
1.17.99.-: (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an oxidized electron acceptor → (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + a reduced electron acceptor ,
1.20.4.2: 2 glutathione + methylarsonate → glutathione disulfide + methylarsonite ,
1.21.1.-: L-tyrosine + 2 iodide + 2 NADP+ ← 3,5-diiodo-L-tyrosine + 2 NADPH + H+ ,
1.97.1.10: 3',5'-diiodothyronine + a reduced electron acceptor → 3'-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.97.1.10: 3,5,3'-triiodo-L-thyronine + iodide + an oxidized electron acceptor + H+ ← L-thyroxine + a reduced electron acceptor ,
1.97.1.10: 3,3',5'-triiodo-L-thyronine + a reduced electron acceptor → 3,3'-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.97.1.11: 3,3',5'-triiodo-L-thyronine + iodide + an oxidized electron acceptor + H+ ← L-thyroxine + a reduced electron acceptor ,
1.97.1.11: 3,5,3'-triiodo-L-thyronine + a reduced electron acceptor → 3,3'-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.97.1.11: 3,5-diiodothyronine + a reduced electron acceptor → 3-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
1.-.-.-: an even numbered straight chain 2,3,4-saturated fatty acid + NAD(P)H + H+ + oxygen → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + NAD(P)+ + H2O ,
2.1.1.1: nicotinamide + S-adenosyl-L-methionine → 1-methylnicotinamide + S-adenosyl-L-homocysteine ,
2.1.1.2: guanidinoacetate + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + creatine + H+ ,
2.1.1.4: N-acetyl-serotonin + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + melatonin + H+ ,
2.1.1.5: L-homocysteine + glycine betaine → L-methionine + dimethylglycine ,
2.1.1.6: 3,4-dihydroxymandelate + S-adenosyl-L-methionine → vanillyl mandelate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: (R)-noradrenaline + S-adenosyl-L-methionine → normetanephrine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: a catechol + S-adenosyl-L-methionine → a guaiacol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: (R)-adrenaline + S-adenosyl-L-methionine → metanephrine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: L-dopa + S-adenosyl-L-methionine → 3-O-methyldopa + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: S-adenosyl-L-methionine + dopamine → S-adenosyl-L-homocysteine + 3-methoxytyramine + H+ ,
2.1.1.6: 3,4-dihydroxyphenylglycol + S-adenosyl-L-methionine → 3-methoxy-4-hydroxyphenylglycol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: 3,4-dihydroxyphenylacetate + S-adenosyl-L-methionine → homovanillate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: orcinol + S-adenosyl-L-methionine → 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine + H+ ,
2.1.1.8: histamine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + Nτ-methylhistamine + H+ ,
2.1.1.10: S-methyl-L-methionine + L-homocysteine → 2 L-methionine + H+ ,
2.1.1.13: L-homocysteine + an N5-methyl-tetrahydrofolate → L-methionine + a tetrahydrofolate ,
2.1.1.17: an L-1-phosphatidyl-ethanolamine + S-adenosyl-L-methionine → a phosphatidyl-N-methylethanolamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.19: a tetrahydrofolate + trimethyl sulfonium ← dimethyl sulfide + an N5-methyl-tetrahydrofolate + H+ ,
2.1.1.20: S-adenosyl-L-methionine + glycine → S-adenosyl-L-homocysteine + sarcosine + H+ ,
2.1.1.28: phenylethanolamine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + N-methylphenylethanolamine + H+ ,
2.1.1.28: S-adenosyl-L-methionine + (R)-noradrenaline → S-adenosyl-L-homocysteine + (R)-adrenaline + H+ ,
2.1.1.43: a [histone]-L-lysine + S-adenosyl-L-methionine → a [histone] N6-methyl-L-lysine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.45: a 5,10-methylene-tetrahydrofolate + dUMP → dTMP + a 7,8-dihydrofolate ,
2.1.1.49: (S)-nicotine + S-adenosyl-L-methionine → nicotine isomethonium ion + S-adenosyl-L-homocysteine ,
2.1.1.49: an amine + S-adenosyl-L-methionine → a methylated amine + S-adenosyl-L-homocysteine ,
2.1.1.62: m7G(5')pppAm + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + m7G(5')pppm6Am + H+ ,
2.1.1.64: 3-demethylubiquinol-10 + S-adenosyl-L-methionine → ubiquinol-10 + S-adenosyl-L-homocysteine + H+ ,
2.1.1.67: a thiopurine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + a thiopurine S-methylether + H+ ,
2.1.1.77: S-adenosyl-L-methionine + a [protein]-L-β-isoaspartate → S-adenosyl-L-homocysteine + a protein L-β-isoaspartate α-methyl ester ,
2.1.1.100: a [protein] c-terminal S-farnesyl-L-cysteine + S-adenosyl-L-methionine → a protein c-terminal s-farnesyl-l-cysteine methyl ester + S-adenosyl-L-homocysteine ,
2.1.1.114: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine → 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.125: S-adenosyl-L-methionine + [histone]-L-arginine → S-adenosyl-L-homocysteine + [histone]-Nω-methyl-arginine + 2 H+ ,
2.1.1.126: S-adenosyl-L-methionine + [myelin basic protein]-L-arginine → S-adenosyl-L-homocysteine + [myelin basic protein]-Nω-methyl-arginine + H+ ,
2.1.1.137: arsenite + S-adenosyl-L-methionine → methylarsonate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.137: S-adenosyl-L-methionine + methylarsonite → S-adenosyl-L-homocysteine + cacodylate + 2 H+ ,
2.1.1.201: 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine → 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-decaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: a 3-(all-trans-polyrenyl)benzene-1,2-diol + S-adenosyl-L-methionine → a 2-methoxy-6-(all-trans-polyprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-nonaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-nonaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-heptaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-heptaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.233: S-adenosyl-L-methionine + a [phosphatase 2A protein] C-terminal L-leucine → S-adenosyl-L-homocysteine + a [phosphatase 2A protein] C-terminal L-leucine methyl ester ,
2.1.1.244: 3 S-adenosyl-L-methionine + an N-terminal-(A/S)PK-[protein] → 3 S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein] + 3 H+ ,
2.1.1.244: 2 S-adenosyl-L-methionine + an N-terminal-PPK-[protein] → 2 S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-PPK-[protein] + 2 H+ ,
2.1.1.282: S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPheS-adenosyl-L-homocysteine + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + H+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl acceptor → S-adenosyl-L-homocysteine + a methylated methyl acceptor + H+ ,
2.1.2.1: L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H2O ,
2.1.2.2: an N10-formyl-tetrahydrofolate + N1-(5-phospho-β-D-ribosyl)glycinamide → a tetrahydrofolate + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + H+ ,
2.1.2.3: an N10-formyl-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide → a tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
2.1.2.5: a 5-formiminotetrahydrofolate + L-glutamate ← N-formimino-L-glutamate + a tetrahydrofolate ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate → L-citrulline + phosphate + H+ ,
2.1.4.1: glycine + L-arginine → guanidinoacetate + L-ornithine ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ← D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate → β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate → β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.3.1.1: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.4: D-glucosamine 6-phosphate + acetyl-CoA → N-acetyl-D-glucosamine 6-phosphate + coenzyme A + H+ ,
2.3.1.5: an arylamine + acetyl-CoA = an N-acetylarylamine + coenzyme A ,
2.3.1.6: choline + acetyl-CoA = acetylcholine + coenzyme A ,
2.3.1.7: L-carnitine + acetyl-CoA ← O-acetylcarnitine + coenzyme A ,
2.3.1.9: acetyl-CoA + propanoyl-CoA = β-ketovaleryl-CoA + coenzyme A ,
2.3.1.9: 2-methylacetoacetyl-CoA + coenzyme A ↔ propanoyl-CoA + acetyl-CoA ,
2.3.1.9: 2 acetyl-CoA ↔ acetoacetyl-CoA + coenzyme A ,
2.3.1.12: acetyl-CoA + dihydrolipoamide = S-acetyldihydrolipoamide + coenzyme A ,
2.3.1.13: glycine + an acyl-CoA = an N-acylglycine + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.16: acetyl-CoA + octanoyl-CoA = 3-oxodecanoyl-CoA + coenzyme A ,
2.3.1.16: jasmonoyl-CoA + acetyl-CoA = OPC4-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: OPC4-CoA + acetyl-CoA = OPC6-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: acetyl-CoA + butanoyl-CoA = 3-oxohexanoyl-CoA + coenzyme A ,
2.3.1.16: 4-hydroxybenzoyl-CoA + acetyl-CoA = 4-hydroxybenzoyl-acetyl-CoA + coenzyme A ,
2.3.1.16: a 2,3,4-saturated fatty acyl CoA + acetyl-CoA ↔ a 3-oxoacyl-CoA + coenzyme A ,
2.3.1.16: OPC6-CoA + acetyl-CoA = OPC8-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + acetyl-CoA = 3,22-dioxochol-4-en-24-oyl-CoA + coenzyme A ,
2.3.1.20: a 1,2-diacyl-sn-glycerol + an acyl-CoA → a triacyl-sn-glycerol + coenzyme A ,
2.3.1.21: L-carnitine + palmitoyl-CoA = L-palmitoylcarnitine + coenzyme A ,
2.3.1.21: a long-chain acyl-CoA + L-carnitine ↔ an O-acyl-L-carnitine + coenzyme A ,
2.3.1.22: a 2-monoglyceride + an acyl-CoA = a 1,2-diacyl-sn-glycerol + coenzyme A ,
2.3.1.23: an acyl-CoA + a 2-lyso-phosphatidylcholine ↔ a phosphatidylcholine + coenzyme A ,
2.3.1.24: phytosphingosine + a very long chain fatty acyl-CoA = a phytoceramide + coenzyme A + H+ ,
2.3.1.24: an acyl-CoA + a sphingoid base = a ceramide + coenzyme A + H+ ,
2.3.1.26: cholesterol + an acyl-CoA = a cholesterol ester + coenzyme A ,
2.3.1.29: glycine + acetyl-CoA = 2-amino-3-oxobutanoate + coenzyme A + H+ ,
2.3.1.37: glycine + succinyl-CoA + H+ → CO2 + 5-aminolevulinate + coenzyme A ,
2.3.1.42: a long-chain acyl-CoA + dihydroxyacetone phosphate = an acylglycerone phosphate + coenzyme A ,
2.3.1.43: a sterol + a phosphatidylcholine = a 2-lyso-phosphatidylcholine + a steryl-ester ,
2.3.1.50: L-serine + palmitoyl-CoA + H+ → CO2 + 3-dehydrosphinganine + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.57: acetyl-CoA + spermidine → N1-acetylspermidine + coenzyme A + H+ ,
2.3.1.57: an aliphatic α,ω-diamine + acetyl-CoA = an aliphatic N-acetyl-diamine + coenzyme A + H+ ,
2.3.1.57: putrescine + acetyl-CoA → N-acetylputrescine + coenzyme A + H+ ,
2.3.1.57: spermine + acetyl-CoA → N1-acetylspermine + coenzyme A + H+ ,
2.3.1.65: glycine + choloyl-CoA → glycocholate + coenzyme A + H+ ,
2.3.1.65: choloyl-CoA + taurine → taurocholate + coenzyme A + H+ ,
2.3.1.65: chenodeoxycholoyl-CoA + taurine → taurochenodeoxycholate + coenzyme A + H+ ,
2.3.1.65: chenodeoxycholoyl-CoA + glycine → glycochenodeoxycholate + coenzyme A + H+ ,
2.3.1.67: acetyl-CoA + a 1-alkyl-2-lyso-sn-glycero-3-phosphocholine = a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + coenzyme A ,
2.3.1.75: a very long chain alcohol + a long-chain acyl-CoA = a wax ester + coenzyme A ,
2.3.1.75: arachidoyl-CoA + 1-dodecanol = arachidoyl dodecanoate + coenzyme A ,
2.3.1.75: a long-chain acyl-CoA + ethanol → a fatty acid-ethyl ester + coenzyme A ,
2.3.1.75: a long-chain acyl-CoA + a long-chain alcohol = a long-chain ester + coenzyme A ,
2.3.1.78: α-D-glucosaminide-[heparan sulfate] + acetyl-CoA = N-acetyl-α-D-glucosaminide-[heparan sulfate] + coenzyme A ,
2.3.1.80: 4-hydroxy-2-nonenal-[L-Cys] conjugate + acetyl-CoA → 4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ ,
2.3.1.80: an L-cysteine-S-conjugate + acetyl-CoA → a mercapturate + coenzyme A + H+ ,
2.3.1.85: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = a long-chain fatty acid + n CO2 + (n+1) coenzyme A + 2n NADP+ ,
2.3.1.87: acetyl-CoA + serotonin → N-acetyl-serotonin + coenzyme A + H+ ,
2.3.1.87: acetyl-CoA + a 2-arylethylamine = an N-acetyl-2-arylethylamine + coenzyme A + H+ ,
2.3.1.97: glycyl-peptide + myristoyl-CoA = N-tetradecanoylglycyl-peptide + coenzyme A ,
2.3.1.108: an [α-tubuline]-L-lysine + acetyl-CoA = an [α-tubulin]-N6-acetyl-L-lysine + coenzyme A + H+ ,
2.3.1.111: an acyl-CoA + n (R)-methylmalonyl-CoA + 2n NADPH + 2n H+ = a multi-methyl-branched acyl-CoA + n CO2 + n coenzyme A + 2n NADP+ ,
2.3.1.118: an N-hydroxy-arylamine + acetyl-CoA = an N-acetoxyarylamine + coenzyme A ,
2.3.1.135: an all-trans retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine → a cellular-retinol-binding protein + an all-trans-retinyl ester + a 1-lysophosphatidylcholine ,
2.3.1.135: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine → a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine ,
2.3.1.137: octanoyl-CoA + L-carnitine = L-octanoylcarnitine + coenzyme A ,
2.3.1.150: salutaridinol + acetyl-CoA → 7-O-acetylsalutaridinol + coenzyme A ,
2.3.1.154: propanoyl-CoA + 4,8,12-trimethyltridecanoyl-CoA = 3-oxopristanoyl-CoA + coenzyme A ,
2.3.1.158: a phosphatidylcholine[out] + a 1,2-diacyl-sn-glycerol[out] → a triacyl-sn-glycerol + a 2-lyso-phosphatidylcholine ,
2.3.1.176: 3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + coenzyme A → choloyl-CoA + propanoyl-CoA ,
2.3.1.176: 3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + coenzyme A → chenodeoxycholoyl-CoA + propanoyl-CoA ,
2.3.1.223: 2,3-didehydroadipyl-CoA + acetyl-CoA = 3-oxo-5,6-didehydrosuberyl-CoA + coenzyme A ,
2.3.1.231: 7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + CO2 + S-adenosyl-L-methionine → wybutosine37 in tRNAPhe + S-adenosyl-L-homocysteine + 2 H+ ,
2.3.1.-: 2 a 1,2-diacyl-sn-glycerol ↔ a triacyl-sn-glycerol + a 2-monoglyceride ,
2.3.1.-: palmitoyl-CoA + malonyl-CoA + H+ → 3-oxo-stearoyl-CoA + CO2 + coenzyme A ,
2.3.2.2: hypoglycin A + glutathione = hypoglycin B + L-cysteinyl-glycine ,
2.3.2.2: glutathione + a standard α amino acid → L-cysteinyl-glycine + an (γ-L-glutamyl)-L-amino acid ,
2.3.2.4: an (γ-L-glutamyl)-L-amino acid → an L-amino acid + 5-oxoproline ,
2.3.3.8: oxaloacetate + acetyl-CoA + ADP + phosphate ← citrate + ATP + coenzyme A ,
2.3.3.10: acetoacetyl-CoA + acetyl-CoA + H2O → (S)-3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ ,
2.3.3.16: oxaloacetate[mitochondrial lumen] + acetyl-CoA[mitochondrial lumen] + H2O[mitochondrial lumen] → citrate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + H+[mitochondrial lumen] ,
2.4.1.1: a glycogen + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: a maltodextrin(n) + phosphate = a maltodextrin(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate = α-D-glucose 1-phosphate + (1,4-α-D-glucosyl)(n-1) ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.1: a debranched limit dextrin + n phosphate → n α-D-glucose 1-phosphate ,
2.4.1.11: UDP-α-D-glucose + (1,4-α-D-glucosyl)(n) glycogenin → (1,4-α-D-glucosyl)(n+1) glycogenin + UDP ,
2.4.1.17: 3,5,3'-triiodo-L-thyronine + UDP-α-D-glucuronate → 3,5,3'-triiodo-L-thyronine phenolic β-D-glucuronide + UDP + H+ ,
2.4.1.17: (S)-nicotine + UDP-α-D-glucuronate → nicotine-glucuronide + UDP ,
2.4.1.17: N-acetyl-serotonin + UDP-α-D-glucuronate → N-acetyl-serotonin glucuronide + UDP ,
2.4.1.17: tetraiodothyroacetate + UDP-α-D-glucuronate → tetraiodothyroacetate ether glucuronide + UDP + H+ ,
2.4.1.17: 3,3',5-triiodothyroacetate + UDP-α-D-glucuronate → triiodothyroacetate ether glucuronide + UDP + H+ ,
2.4.1.17: 5-hydroxytryptophol + UDP-α-D-glucuronate → 5-hydroxytryptophol glucuronide + UDP ,
2.4.1.17: L-thyroxine + UDP-α-D-glucuronate → L-thyroxine phenolic β-D-glucuronide + UDP + H+ ,
2.4.1.17: 3,5,3'-triiodo-L-thyronine + UDP-α-D-glucuronate → 3,5,3'-triiodo-L-thyronine acyl β-D-glucuronide + UDP + H+ ,
2.4.1.17: mycophenolate + UDP-α-D-glucuronate = mycophenolic acid phenolic glucuronide + UDP + H+ ,
2.4.1.17: oleanolate + UDP-α-D-glucuronate = oleanolate 3 β-D-glucuronoside + UDP + H+ ,
2.4.1.17: 3,3',5-triiodothyroacetate + UDP-α-D-glucuronate → triiodothyroacetate ester glucuronide + UDP ,
2.4.1.17: L-thyroxine + UDP-α-D-glucuronate → L-thyroxine acyl β-D-glucuronide + UDP + H+ ,
2.4.1.17: mycophenolate + UDP-α-D-glucuronate = mycophenolic acid O-acyl-glucuronide + UDP ,
2.4.1.17: trans-3'-hydroxycotinine + UDP-α-D-glucuronate → trans-3-hydroxycotinine-glucuronide + UDP + H+ ,
2.4.1.17: a non-glucuronosylated glucuronoside acceptor + UDP-α-D-glucuronate = a glucuronosylated glucuronoside acceptor + UDP ,
2.4.1.17: tetraiodothyroacetate + UDP-α-D-glucuronate → tetraiodothyroacetate ester glucuronide + UDP ,
2.4.1.17: cotinine + UDP-α-D-glucuronate → cotinine-glucuronide + UDP ,
2.4.1.18: a 1,4-α-D-glucan = a glycogen ,
2.4.1.18: a glucosylated glycogenin → a glycogen ,
2.4.1.18: n a 1,4-α-D-glucan = n starch + n H2O ,
2.4.1.22: UDP-α-D-galactose + β-D-glucose = α-lactose + UDP + H+ ,
2.4.1.25: a limit dextrin → a limit dextrin with short branches ,
2.4.1.37: UDP-α-D-galactose + a glycoprotein-α-L-fucosyl-(1,2)-D-galactose = UDP + a galactosyl-(1->3)-[α-L-fucosyl(1->2)]-D-galactosyl-R + H+ ,
2.4.1.38: UDP-α-D-galactose + N-acetyl-β-D-galactosyl-(1,4)-[N-acetyl-β-D-glucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-R → I antigen + UDP + H+ ,
2.4.1.38: UDP-α-D-galactose + an N-acetyl-β-D-glucosaminyl-R → β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.38: UDP-α-D-galactose + N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-R → i antigen + UDP + H+ ,
2.4.1.40: UDP-N-acetyl-D-galactosamine + a glycoprotein-α-L-fucosyl-(1,2)-D-galactose = glycoprotein N-acetyl-α-D-galactosaminyl-(1,3)-[α-L-fucosyl-(1,2)]-D-galactose + UDP + H+ ,
2.4.1.41: UDP-N-acetyl-α-D-galactosamine + a [glycoprotein]-(L-serine/L-threonine) → N-acetyl-α-D-galactosalaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.45: UDP-α-D-galactose + a 2-(2-hydroxyacyl)sphingosine = a 1-(β-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP + H+ ,
2.4.1.50: UDP-α-D-galactose + a [procollagen]-5-hydroxy-L-lysine = a procollagen 5-(galactosyloxy)-L-lysine + UDP + H+ ,
2.4.1.62: UDP-α-D-galactose + gangloside GM2 = ganglioside GM1a + UDP + H+ ,
2.4.1.65: GDP-L-fucose + 1,3-β-D-galactosyl-N-acetyl-D-glucosaminyl-R = 1,3-β-D-galactosyl-(α-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl- R + GDP + H+ ,
2.4.1.68: GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine = GDP + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-[α-L-fucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl}asparagine + H+ ,
2.4.1.69: GDP-L-fucose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide = III2-α-fucosyllactotetraosylceramide + GDP + H+ ,
2.4.1.79: UDP-N-acetyl-α-D-galactosamine + an α-D-galactosyl-(1->4)-β-D-galactosyl-(1->4)-β-D-glucosylceramide = an N-acetyl-β-D-galactosaminyl-(1,3)-α-D-galactosyl-(1,4)-β-D-galactosyl-(1,4)-β-D-glucosylceramide + UDP + H+ ,
2.4.1.80: UDP-α-D-glucose + an N-acylsphingosine + H+ = a D-glucosyl-N-acylsphinganine + UDP ,
2.4.1.80: UDP-α-D-glucose + a dihydroceramide = a D-glucosyl-N-acylsphinganine + UDP + H+ ,
2.4.1.83: a dolichyl phosphate + GDP-α-D-mannose → a dolichyl β-D-mannosyl phosphate + GDP ,
2.4.1.87: UDP-α-D-galactose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-D-galactosyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R + UDP + H+ ,
2.4.1.90: UDP-α-D-galactose + N-acetyl-β-D-glucosamine = β-D-galactosyl-1,4-N-acetyl-β-D-glucosamine + UDP + H+ ,
2.4.1.92: UDP-N-acetyl-α-D-galactosamine + a 1-O-[O-(N-acetyl-α-neuraminyl)-2,3-β-D-galactosyl-1,4-β-D-glucosyl]ceramide = gangloside GM2 + UDP + H+ ,
2.4.1.101: UDP-N-acetyl-α-D-glucosamine + a (mannosyl)5-N-glycan = a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan + UDP + H+ ,
2.4.1.102: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine → β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.117: UDP-α-D-glucose + a dolichyl phosphate → a dolichyl β-D-glucosyl phosphate + UDP ,
2.4.1.122: UDP-α-D-galactose + N-acetyl-α-D-galactosalaminyl-[glycoprotein] → β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + UDP + H+ ,
2.4.1.131: a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol + 2 GDP-α-D-mannose → a (mannosyl)5-(N-acetylglucosaminyl)2-diphosphodolichol + 2 GDP + 2 H+ ,
2.4.1.132: a mannosyl-(N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.133: UDP-α-D-galactose + O-β-D-xylosyl-[core protein] → β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.141: an N-acetylglucosaminyl-diphosphodolichol + UDP-N-acetyl-α-D-glucosamine → an (N-acetylglucosaminyl)2-diphosphodolichol + UDP + H+ ,
2.4.1.142: an (N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a mannosyl-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.143: α-D-mannosyl-1,6-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3)-β-D-mannosyl-[glycoprotein] + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3)-β-D-mannosyl-[glycoprotein] + UDP + H+ ,
2.4.1.144: N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-(N-acetyl-β-D-glucosaminyl-1,4)-β-D-mannosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.145: (N-acetyl-β-D-glucosaminyl-1,2)-α-D-mannosyl-1,3-(β-N-acetyl-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-R + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-α-D-mannosyl-1,3-(β-N-acetyl-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-R + UDP + H+ ,
2.4.1.146: β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP-N-acetyl-α-D-glucosamine → N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.149: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.150: UDP-N-acetyl-α-D-glucosamine + i antigen → N-acetyl-β-D-galactosyl-(1,4)-[N-acetyl-β-D-glucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.150: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → N-acetyl-β-D-glucosaminyl-(1→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.152: GDP-L-fucose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → Lewis x epitope + GDP + H+ ,
2.4.1.155: [(2,4),(2)]-N-linked glycan + UDP-N-acetyl-α-D-glucosamine = [(2,4),(2,6)]-N-linked glycan + UDP + H+ ,
2.4.1.174: UDP-N-acetyl-D-galactosamine + β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] = α-N-acetyl-D-galactosaminyl-(1->4)-β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.174: UDP-N-acetyl-D-galactosamine + D-glucuronyl-1,3-β-D-galactosylproteoglycan → N-acetyl-D-galactosaminyl-1,4-β-D-glucuronyl-1,3-β-D-galactosyl-[proteoglycan] + UDP + H+ ,
2.4.1.175: UDP-N-acetyl-α-D-galactosamine + β-D-glucuronosyl-[chondroitin/dermatan] → N-acetyl-β-D-galactosaminide-[chondroitin/dermatan] + UDP + H+ ,
2.4.1.198: an L-1-phosphatidyl-inositol + UDP-N-acetyl-α-D-glucosamine = a 6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + UDP + H+ ,
2.4.1.212: N-acetyl-α-D-glucosaminide-[hyaluronan] + UDP-α-D-glucuronate = β-D-glucuronosyl-[hyaluronan] + UDP ,
2.4.1.212: UDP-N-acetyl-α-D-glucosamine + β-D-glucuronosyl-[hyaluronan] = N-acetyl-α-D-glucosaminide-[hyaluronan] + UDP ,
2.4.1.214: GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine = N(4)-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-[α-L-fucosyl-(1,3)]-N-acetyl-β-D-glucosaminyl}asparagine + GDP + H+ ,
2.4.1.221: GDP-β-L-fucose + a [protein]-L-serine = GDP + a [protein]-3-O-L-fucosyl-L-serine + H+ ,
2.4.1.222: UDP-N-acetyl-α-D-glucosamine + a fucosyl-protein = UDP + O-β-D-GlcNAc-fucosyl-protein ,
2.4.1.223: β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP-N-acetyl-α-D-glucosamine → α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.224: β-D-glucuronosyl-[heparan sulfate] + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-glucosaminide-[heparan sulfate] + UDP + H+ ,
2.4.1.225: N-acetyl-α-D-glucosaminide-[heparan sulfate] + UDP-α-D-glucuronate → β-D-glucuronosyl-[heparan sulfate] + UDP ,
2.4.1.226: N-acetyl-β-D-galactosaminide-[chondroitin/dermatan] + UDP-α-D-glucuronate → β-D-glucuronosyl-[chondroitin/dermatan] + UDP ,
2.4.1.228: UDP-α-D-galactose + a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide = an α-D-galactosyl-(1->4)-β-D-galactosyl-(1->4)-β-D-glucosylceramide + UDP + H+ ,
2.4.1.244: UDP-N-acetyl-α-D-galactosamine + an N-acetyl-β-D-glucosaminyl-R = N-acetyl-β-D-galactosaminyl-(1->4)-N-acetyl-β-D-glucosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) → UDP + an N-acetyl-α-D-glucosaminyl-[glycoprotein] + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [protein]-L-threonine = UDP + an N-acetyl-α-D-glucosaminyl-L-threonine-[glycoprotein] + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [protein]-L-serine = UDP + an N-acetyl-α-D-glucosaminyl-L-serine-[glycoprotein] + H+ ,
2.4.1.256: a (glucosyl)2(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → dolichyl diphosphooligosaccharide + a dolichyl phosphate + H+ ,
2.4.1.257: a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.258: a (mannosyl)5-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.259: a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.260: a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.261: a (mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.265: a glucosyl-(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → a (glucosyl)2(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.267: a (mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → a glucosyl-(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.274: UDP-α-D-galactose + a D-glucosyl-N-acylsphingosine = a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.1.275: an N-acetyl-β-D-glucosaminyl-(1-3)-β-D-galactosyl-(1-4)-β-D-glucosyl-(1↔1)-ceramide + UDP-α-D-galactose = a β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1-3)-β-D-galactosyl-1,4-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.1.-: an N-acetyl-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide + UDP-α-D-galactose = β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.2.1: a purine ribonucleoside + arsenate → ribose-1-arsenate + a purine base ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine ,
2.4.2.1: xanthosine + phosphate ↔ α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: a purine ribonucleoside + phosphate = α-D-ribose-1-phosphate + a purine base ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine ,
2.4.2.2/2.4.2.4: thymidine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + thymine ,
2.4.2.2/2.4.2.3: uridine + phosphate ↔ α-D-ribose-1-phosphate + uracil ,
2.4.2.3: 2'-deoxyuridine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + uracil ,
2.4.2.7: AMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + adenine ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + hypoxanthine ,
2.4.2.9: UMP + diphosphate = 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.12: β-nicotinamide D-ribonucleotide + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + nicotinamide + H+ ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.26: a core protein L-serine + UDP-α-D-xylose → O-β-D-xylosyl-[core protein] + UDP ,
2.4.2.28: S-methyl-5'-thioadenosine + phosphate → S-methyl-5-thio-α-D-ribose 1-phosphate + adenine ,
2.4.2.31: a [protein]-L-arginine + NAD+ = a protein-Nω-(ADP-D-ribosyl)-L-arginine + nicotinamide + H+ ,
2.4.2.36: a diphthamide-[translation elongation factor 2] + NAD+ = N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide ,
2.4.99.1: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-N-acetylneuraminyl-2,6-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + CMP + H+ ,
2.4.99.4: β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + CMP-N-acetyl-β-neuraminate → α-N-acetylneuraminyl-2,3-β-D-galactosyl-1,3-N-acetyl-α-D-galactosaminyl-[glycoprotein] + CMP + H+ ,
2.4.99.6: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + CMP + H+ ,
2.4.99.7: α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-[(α-N-acetylneuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP + H+ ,
2.4.99.8: α-N-acetylneuraminyl-2,3-β-D-galactosyl-R + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-2,8-α-N-acetylneuraminyl-2,3-β-D-galactosyl-R + CMP ,
2.4.99.9: a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP-N-acetyl-β-neuraminate = a 1-O-[O-(N-acetyl-α-neuraminyl)-2,3-β-D-galactosyl-1,4-β-D-glucosyl]ceramide + CMP ,
2.4.99.10: β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosylceramide + CMP + H+ ,
2.4.99.20: nicotinate + NADP+ = nicotinate-adenine dinucleotide phosphate + nicotinamide ,
2.4.99.-: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1->3)-N-acetyl-α-D-galactosaminyl-R = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP + H+ ,
2.4.99.-: β-D-galactosyl-(1->3)-N-acetyl-β-D-glucosaminyl-R[Golgi lumen] + CMP-N-acetyl-β-neuraminate[Golgi lumen] = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R[Golgi lumen] + CMP[Golgi lumen] + H+[Golgi lumen] ,
2.5.1.1: dimethylallyl diphosphate + isopentenyl diphosphate → geranyl diphosphate + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.10: geranyl diphosphate + isopentenyl diphosphate → (2E,6E)-farnesyl diphosphate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.17: cobinamide + ATP = adenosylcobinamide + PPPi ,
2.5.1.17: ATP + cob(I)alamin = coenzyme B12 + PPPi ,
2.5.1.17: cob(I)yrinate a,c-diamide + ATP = adenosyl-cobyrinate a,c-diamide + PPPi ,
2.5.1.18: glutathione + 4-hydroxy-2-nonenal → 4-hydroxy-2-nonenal-glutathione conjugate ,
2.5.1.18: 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H+ ,
2.5.1.18: glutathione + RX → a glutathione-toxin conjugate + HX ,
2.5.1.21: 2 (2E,6E)-farnesyl diphosphate + NAD(P)H + H+ → squalene + NAD(P)+ + 2 diphosphate ,
2.5.1.22: spermidine + S-adenosyl 3-(methylthio)propylamine → spermine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.26: an acylglycerone phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain carboxylate ,
2.5.1.29: isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate → geranylgeranyl diphosphate + diphosphate ,
2.5.1.32: 2 2-cis,6-trans,10-trans-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate ,
2.5.1.39: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate → 3-decaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.56: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = N-acetyl-β-neuraminate + phosphate ,
2.5.1.57: N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O → N-acetyl-β-neuraminate 9-phosphate + phosphate ,
2.5.1.58: a [protein]-L-cysteine + (2E,6E)-farnesyl diphosphate = a [protein]-S-farnesyl-L-cysteine + diphosphate ,
2.5.1.60: geranylgeranyl diphosphate + a [protein]-L-cysteine = a [protein]-S-geranylgeranyl-L-cysteine + diphosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.87: (2E,6E)-farnesyl diphosphate + 13 isopentenyl diphosphate → di-trans, poly-cis-polyprenyl diphosphate (C80) + 13 diphosphate ,
2.5.1.91: (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate → all-trans-decaprenyl diphosphate + 7 diphosphate ,
2.5.1.99: 2 geranylgeranyl diphosphate = all-trans-phytoene + 2 diphosphate ,
2.5.1.103: 2 (2E,6E)-farnesyl diphosphate = presqualene diphosphate + diphosphate ,
2.5.1.108: an L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H+ ,
2.5.1.114: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPheS-methyl-5'-thioadenosine + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe + H+ ,
2.5.1.-: heme b + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate ,
2.6.1.1: L-aspartate[mitochondrial lumen] + 2-oxoglutarate[mitochondrial lumen] = L-glutamate[mitochondrial lumen] + oxaloacetate[mitochondrial lumen] ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ oxaloacetate + L-glutamate ,
2.6.1.2: 2-oxoglutarate + L-alanine → L-glutamate + pyruvate ,
2.6.1.3: 2-oxoglutarate + L-cysteine → L-glutamate + 3-mercaptopyruvate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate → 4-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.7: L-kynurenine + 2-oxoglutarate ↔ L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate ,
2.6.1.7: 3-hydroxy-L-kynurenine + 2-oxoglutarate ↔ 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate ,
2.6.1.13: L-ornithine + a 2-oxo carboxylate = a standard α amino acid + L-glutamate-5-semialdehyde ,
2.6.1.13: L-ornithine + 2-oxoglutarate ↔ L-glutamate + L-glutamate-5-semialdehyde ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.19: 2-oxoglutarate + 4-aminobutanoate → L-glutamate + succinate semialdehyde ,
2.6.1.19: 2-oxoglutarate + β-alanine ↔ L-glutamate + malonate semialdehyde ,
2.6.1.22: 2-oxoglutarate + (S)-3-amino-2-methylpropanoate ↔ L-glutamate + (S)-methylmalonate-semialdehyde ,
2.6.1.23: 2-oxoglutarate + erythro-4-hydroxy-L-glutamate ↔ L-glutamate + 4-hydroxy-2-oxoglutarate ,
2.6.1.39: 2-oxoglutarate + L-2-aminoadipate → L-glutamate + 2-oxoadipate ,
2.6.1.40: pyruvate + (R)-3-amino-2-methylpropanoate ↔ L-alanine + (S)-methylmalonate-semialdehyde ,
2.6.1.42: L-isoleucine + 2-oxoglutarate → (S)-3-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.42: L-valine + 2-oxoglutarate → 3-methyl-2-oxobutanoate + L-glutamate ,
2.6.1.44: glyoxylate + L-alanine ↔ glycine + pyruvate ,
2.6.1.49: L-dopa + 2-oxoglutarate ↔ 3,4-dihydroxyphenylpyruvate + L-glutamate ,
2.6.1.51: pyruvate + L-serine ↔ L-alanine + hydroxypyruvate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate = 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ← 3-phospho-hydroxypyruvate + L-glutamate ,
2.6.1.57: 2-oxoglutarate + L-tyrosine → L-glutamate + 4-hydroxyphenylpyruvate ,
2.6.1.64: 2-oxo-3-phenylpropanoate + L-glutamine ↔ L-phenylalanine + 2-oxoglutaramate ,
2.6.1.82: 4-aminobutanal ↔ 1-pyrroline + H2O ,
2.6.1.88: L-methionine + a 2-oxo carboxylate ← 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.1.-: L-methionine + 2-oxoglutaramate ↔ 2-oxo-4-methylthiobutanoate + L-glutamine ,
2.6.1.-: 3-sulfinoalanine + 2-oxoglutarate ↔ L-glutamate + 3-sulfinopyruvate ,
2.7.1.1: a D-hexose + ATP = D-hexose 6-phosphate + ADP + H+ ,
2.7.1.1/2.7.1.2: α-D-glucose + ATP = α-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.2: D-glucopyranose + ATP → D-glucopyranose 6-phosphate + ADP + H+ ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.3: β-D-fructofuranose + ATP → β-D-fructofuranose 1-phosphate + ADP + H+ ,
2.7.1.6: α-D-galactose + ATP → α-D-galactose 1-phosphate + ADP + H+ ,
2.7.1.7: D-mannopyranose + ATP → α-D-mannose 6-phosphate + ADP + H+ ,
2.7.1.11: ATP + β-D-fructofuranose 6-phosphate → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.12: ATP + D-gluconate = D-gluconate 6-phosphate + ADP + H+ ,
2.7.1.14: D-sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H+ ,
2.7.1.15: α-D-ribofuranose + ATP = α-D-ribose 5-phosphate + ADP + H+ ,
2.7.1.17: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H+ ,
2.7.1.20: adenosine + ATP → AMP + ADP + H+ ,
2.7.1.22: 1-(β-D ribofuranosyl)nicotinamide + ATP = β-nicotinamide D-ribonucleotide + ADP + H+ ,
2.7.1.23: ATP + NAD+ → ADP + NADP+ + H+ ,
2.7.1.24: 3'-dephospho-CoA + ATP → ADP + coenzyme A + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP → 3'-phosphoadenylyl-sulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.28: D-glyceraldehyde + ATP → D-glyceraldehyde 3-phosphate + ADP + H+ ,
2.7.1.29: dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.31: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → (R)-4'-phosphopantothenate + ADP + H+ ,
2.7.1.35: ATP + pyridoxine → ADP + pyridoxine 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxal → ADP + pyridoxal 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxamine → ADP + pyridoxamine 5'-phosphate + H+ ,
2.7.1.36: (R)-mevalonate + ATP → (R)-mevalonate 5-phosphate + ADP + H+ ,
2.7.1.40: pyruvate + ATP ← phosphoenolpyruvate + ADP + H+ ,
2.7.1.48: cytidine + GTP = CMP + GDP + H+ ,
2.7.1.48: uridine + ATP → UMP + ADP + H+ ,
2.7.1.48: cytidine + ATP → CMP + ADP + H+ ,
2.7.1.48: uridine + GTP = UMP + GDP + H+ ,
2.7.1.52: L-fucopyranose + ATP → β-L-fucose 1-phosphate + ADP + H+ ,
2.7.1.59: N-acetyl-β-D-glucosamine + ATP → N-acetyl-D-glucosamine 6-phosphate + ADP + H+ ,
2.7.1.60: N-acetyl-D-mannosamine + ATP → N-acetyl-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.60: an N-acyl-D-mannosamine + ATP = an N-acyl-α-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.67: an L-1-phosphatidyl-inositol + ATP → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + H+ ,
2.7.1.68: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+ ,
2.7.1.74/2.7.1.76/2.7.1.145: 2'-deoxyadenosine + ATP → dAMP + ADP + H+ ,
2.7.1.74/2.7.1.113/2.7.1.145: 2'-deoxyguanosine + ATP → dGMP + ADP + H+ ,
2.7.1.74: 2'-deoxycytidine + a nucleoside triphosphate → dCMP + a nucleoside diphosphate + H+ ,
2.7.1.82: ethanolamine + ATP → phosphoryl-ethanolamine + ADP + H+ ,
2.7.1.91: sphinganine + ATP = sphinganine 1-phosphate + ADP + H+ ,
2.7.1.94: a 1-monoglyceride + ATP = a 1-acyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.105: β-D-fructofuranose 6-phosphate + ATP → β-D-fructose 2,6-bisphosphate + ADP + H+ ,
2.7.1.106: α-D-glucose 1-phosphate + 1,3-bisphospho-D-glycerate = α-glucose 1,6-bisphosphate + 3-phospho-D-glycerate + H+ ,
2.7.1.107: ATP + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.108: a dolichol + CTP → a dolichyl phosphate + CDP + H+ ,
2.7.1.127: D-myo-inositol (1,4,5)-trisphosphate + ATP → D-myo-inositol (1,3,4,5)-tetrakisphosphate + ADP + H+ ,
2.7.1.134: D-myo-inositol (3,4,5,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.137: an L-1-phosphatidyl-inositol + ATP → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+ ,
2.7.1.138: a dihydroceramide + ATP = a dihydroceramide 1-phosphate + ADP + H+ ,
2.7.1.138: a ceramide + ATP = a ceramide 1-phosphate + ADP + H+ ,
2.7.1.140: D-myo-inositol (1,3,4,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.145: 2'-deoxyuridine + ATP → dUMP + ADP + H+ ,
2.7.1.145: thymidine + ATP → dTMP + ADP + H+ ,
2.7.1.32: choline + ATP → phosphocholine + ADP + H+ ,
2.7.1.147: D-glucosamine + ADP = D-glucosamine 6-phosphate + AMP + H+ ,
2.7.1.147: β-D-glucose + ADP = β-D-glucose 6-phosphate + AMP + H+ ,
2.7.1.149: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+ ,
2.7.1.150: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP → 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + H+ ,
2.7.1.151: D-myo-inositol (1,4,5,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.151: D-myo-inositol (1,3,4,5)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.153: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP → 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+ ,
2.7.1.154: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+ ,
2.7.1.157: ATP + N-acetyl-α-D-galactosamine = ADP + N-acetyl-α-D-galactosamine 1-phosphate + H+ ,
2.7.1.158: D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP → 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ADP + H+ ,
2.7.1.159: D-myo-inositol (1,3,4)-trisphosphate + ATP → D-myo-inositol (1,3,4,6)-tetrakisphosphate + ADP + H+ ,
2.7.1.159: D-myo-inositol (1,3,4)-trisphosphate + ATP → D-myo-inositol (1,3,4,5)-tetrakisphosphate + ADP + H+ ,
2.7.1.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP → a diphospho-1D-myo-inositol tetrakisphosphate + ADP ,
2.7.1.-: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+ ,
2.7.1.-: an N-acetyl-D-galactosamine + ATP = N-acetyl-D-galactosamine 6-phosphate + ADP + H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.11: L-glutamate[mitochondrial lumen] + ATP[mitochondrial lumen] → γ-L-glutamyl 5-phosphate[mitochondrial lumen] + ADP[mitochondrial lumen] ,
2.7.3.2: creatine + ATP ↔ creatine-phosphate + ADP + H+ ,
2.7.4.2: (R)-mevalonate 5-phosphate + ATP ↔ (R)-mevalonate diphosphate + ADP ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP = a nucleoside triphosphate + ADP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.10: a nucleoside triphosphate + AMP = a nucleoside diphosphate + ADP ,
2.7.4.12/2.7.4.13: dTMP + ATP → ADP + dTDP ,
2.7.4.13: ATP + dAMP → ADP + dADP ,
2.7.4.13: ATP + dGMP → ADP + dGDP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.21: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ADP ,
2.7.4.21: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + ADP ,
2.7.4.21/2.7.4.24: 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + ATP → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.4.24: 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + ATP → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.24: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ATP → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.24: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + ADP ,
2.7.4.24: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ATP → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.6.1: D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.2: thiamin + ATP → thiamin diphosphate + AMP + H+ ,
2.7.7.1: β-nicotinamide D-ribonucleotide + ATP + H+ → NAD+ + diphosphate ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.3: 4'-phosphopantetheine + ATP + H+ → 3'-dephospho-CoA + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ → UDP-α-D-glucose + diphosphate ,
2.7.7.10: α-D-galactose 1-phosphate + UTP + H+ = UDP-α-D-galactose + diphosphate ,
2.7.7.12: UDP-α-D-glucose + α-D-galactose 1-phosphate → UDP-α-D-galactose + α-D-glucose 1-phosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.14: phosphoryl-ethanolamine + CTP + H+ → CDP-ethanolamine + diphosphate ,
2.7.7.15: phosphocholine + CTP + H+ → CDP-choline + diphosphate ,
2.7.7.18: ATP + β-nicotinate D-ribonucleotide + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.22: α-D-mannose 1-phosphate + GDP + H+ = GDP-α-D-mannose + phosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.30: β-L-fucose 1-phosphate + GTP + H+ → GDP-L-fucose + diphosphate ,
2.7.7.34: α-D-glucose 1-phosphate + GTP + H+ → GDP-α-D-glucose + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.43: N-acetyl-β-neuraminate + CTP → CMP-N-acetyl-β-neuraminate + diphosphate ,
2.7.7.43: an N-acyl-β-neuraminate + CTP + H+ = a CMP-N-acyl-β-neuraminate + diphosphate ,
2.7.7.50: a 5'-diphospho-purine-[mRNA] + GTP + H+ → a 5'-(5'-triphosphoguanosine)-purine-[mRNA] + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate = a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.75: ATP + molybdopterin + H+ → molybdopterin adenine dinucleotide + diphosphate ,
2.7.7.78: GDP-α-D-glucose + phosphate ↔ α-D-glucose 1-phosphate + GDP + H+ ,
2.7.7.84: 3 ATP + H+ → pppA2'p5'A2'p5'A + 2 diphosphate ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.1: a 1,2-diacyl-sn-glycerol + CDP-ethanolamine → an L-1-phosphatidyl-ethanolamine + CMP + H+ ,
2.7.8.2: a 1,2-diacyl-sn-glycerol + CDP-choline → a phosphatidylcholine + CMP + H+ ,
2.7.8.2: 1,2-dipalmitoylglycerol + CDP-choline → 1,2-dipalmitoyl-phosphatidylcholine + CMP + H+ ,
2.7.8.5: a CDP-diacylglycerol + sn-glycerol 3-phosphate → CMP + an L-1-phosphatidylglycerol-phosphate + H+ ,
2.7.8.11: a CDP-diacylglycerol + myo-inositol → an L-1-phosphatidyl-inositol + CMP + H+ ,
2.7.8.15: a dolichyl phosphate + UDP-N-acetyl-α-D-glucosamine → an N-acetylglucosaminyl-diphosphodolichol + UMP ,
2.7.8.17: a lysosomal-enzyme-D-mannose + UDP-N-acetyl-α-D-glucosamine = a lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose + UMP ,
2.7.8.27: a ceramide + a phosphatidylcholine ↔ a sphingomyelin + a 1,2-diacyl-sn-glycerol ,
2.7.8.29: an L-1-phosphatidyl-ethanolamine + L-serine → an L-1-phosphatidylserine + ethanolamine ,
2.7.8.-: a phosphatidylcholine + L-serine = an L-1-phosphatidylserine + choline ,
2.7.8.-: 2 an L-1-phosphatidyl-glycerol = a cardiolipin + glycerol ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.7.10.2/2.7.12.1: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate + H+ ,
2.7.11.18: ATP + myosin light-chain + H+ = ADP + myosin light-chain phosphate ,
2.8.1.1: hydrogen cyanide + thiosulfate → sulfite + thiocyanate + 2 H+ ,
2.8.1.2: hydrogen cyanide + 3-mercaptopyruvate → pyruvate + thiocyanate + H+ ,
2.8.1.7: an [L-cysteine desulfurase] + L-cysteine → an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.7: an [L-cysteine desulfurase] L-cysteine persulfide + an unsulfurated [sulfur carrier] ↔ an [L-cysteine desulfurase]-L-cysteine + a sulfurated [sulfur carrier] ,
2.8.1.7: an [L-cysteine desulfurase]-L-cysteine + L-cysteine → an [L-cysteine desulfurase] L-cysteine persulfide + L-alanine ,
2.8.1.7: a [cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-cysteine → an S-sulfanyl-[cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-alanine ,
2.8.1.7: L-cysteine + an unsulfurated [sulfur carrier] → L-alanine + a sulfurated [sulfur carrier] ,
2.8.1.9: MoO2-molybdopterin cofactor + L-cysteine + 2 H+ → thio-molybdenum cofactor + L-alanine + H2O ,
2.8.1.12: cyclic pyranopterin phosphate + 2 a thiocarboxylated small subunit of molybdopterin synthase + H2O → 2 a small subunit of molybdopterin synthase + molybdopterin ,
2.8.2.1: serotonin + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + serotonin O-sulfate + H+ ,
2.8.2.1: dopamine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H+ ,
2.8.2.1: 3'-phosphoadenylyl-sulfate + 4-methylphenol = adenosine 3',5'-bisphosphate + 4-methylphenyl sulfate + H+ ,
2.8.2.1: a phenol + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + an aryl sulfate ,
2.8.2.1: N-acetyl-serotonin + 3'-phosphoadenylyl-sulfate → N-acetyl-serotonin sulfate + adenosine 3',5'-bisphosphate ,
2.8.2.1: 3,5,3'-triiodo-L-thyronine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + triiodothyronine sulfate + H+ ,
2.8.2.1: 5-hydroxytryptophol + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + 5-hydroxytryptophol sulfate + H+ ,
2.8.2.1: 3'-phosphoadenylyl-sulfate + indoxyl = adenosine 3',5'-bisphosphate + indoxyl sulfate + H+ ,
2.8.2.1: 6-hydroxymelatonin + 3'-phosphoadenylyl-sulfate → 6-sulfatoxymelatonin + adenosine 3',5'-bisphosphate ,
2.8.2.1: L-thyroxine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + thyroxine sulfate + H+ ,
2.8.2.2: an alcohol + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + an organosulfate + H+ ,
2.8.2.4: estrone + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + estrone-sulfate + H+ ,
2.8.2.5: [chondroitin]-N-acetyl-galactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-4-O-sulfo-N-acetylgalactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.8: [heparan sulfate]-α-D-glucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine + adenosine 3',5'-bisphosphate ,
2.8.2.11: a cerebroside + 3'-phosphoadenylyl-sulfate = a cerebroside 3-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.14: taurolithocholate + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate + H+ ,
2.8.2.14: glycolithocholate + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + glycolithocholate-3-sulfate + H+ ,
2.8.2.17: [chondroitin]-N-acetyl-galactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-6-O-sulfo-N-acetylgalactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.21: a keratan + 3'-phosphoadenylyl-sulfate = keratan sulfate + adenosine 3',5'-bisphosphate ,
2.8.2.23: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.29: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.30: [heparan sulfate]-α-D-glucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-glucosamine 3-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.33: [chondroitin]-4-O-sulfo-N-acetylgalactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-4,6-di-O-sulfo-N-acetyl-D-galactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.33: [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine + 3'-phosphoadenylyl-sulfate → [dermatan]-4,6-di-O-sulfo-N-acetyl-D-galactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.35: [dermatan]-N-acetyl-D-galactosamine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine + H+ ,
2.8.2.-: [dermatan]-α-L-iduronate + 3'-phosphoadenylyl-sulfate → [dermatan-sulfate]-2-O-sulfo-α-L-iduronate + adenosine 3',5'-bisphosphate ,
2.8.2.-: [heparan-sulfate]-α-L-iduronate + 3'-phosphoadenylyl-sulfate → [heparan-sulfate]-2-O-sulfo-α-L-iduronate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 6-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan-sulfate]-β-D-glucuronate + 3'-phosphoadenylyl-sulfate = [heparan-sulfate]-2-O-sulfo-β-D-glucuronate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan sulfate]-α-D-N-sulfoglucosamine 6-O-sulfate + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3,6-O-bissulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [chondroitin-sulfate]-β-D-glucuronate + 3'-phosphoadenylyl-sulfate → [chondroitin-sulfate]-2-O-sulfo-β-D-glucuronate + adenosine 3',5'-bisphosphate ,
2.8.3.5: a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate ,
2.8.3.5: succinyl-CoA + acetoacetate → succinate + acetoacetyl-CoA ,
2.10.1.1: molybdopterin adenine dinucleotide + molybdate + H+ → MoO2-molybdopterin cofactor + AMP + H2O ,
3.1.1.1: an all-trans-retinyl ester + H2O → all-trans-retinol + a long-chain fatty acid + H+ ,
3.1.1.1: methyl (indol-3-yl)acetate + H2O → indole-3-acetate + methanol + H+ ,
3.1.1.1: all-trans-retinyl palmitate + H2O → all-trans-retinol + palmitate + H+ ,
3.1.1.1: a carboxylic ester + H2O ↔ an alcohol + a carboxylate + H+ ,
3.1.1.1: all-trans-retinyl palmitate + H2O → a retinol + palmitate + H+ ,
3.1.1.1: a methyl jasmonate + H2O → a jasmonic acid + methanol + H+ ,
3.1.1.1: salicyl-6-hydroxy-2-cyclohexene-on-oyl + H2O → 6-hydroxy-2-cyclohexen-one-carboxylate + salicyl alcohol + H+ ,
3.1.1.1: 1-O-methylsalicylate + H2O → salicylate + methanol + H+ ,
3.1.1.2: a phenyl acetate + H2O → a phenol + acetate + H+ ,
3.1.1.3: a triglyceride + H2O → a 1,2-diglyceride + a fatty acid + H+ ,
3.1.1.3: a dietary all-trans-retinyl ester + H2O → all-trans-retinol + a long-chain fatty acid + H+ ,
3.1.1.3: tributyrin + H2O → 1,2-dibutyrin + butanoate + H+ ,
3.1.1.4: a phosphatidylcholine + H2O → a 2-lyso-phosphatidylcholine + a fatty acid + H+ ,
3.1.1.4: an L-1-phosphatidyl-ethanolamine + H2O → a fatty acid + a 2-lyso-phosphatidyl-ethanolamine + H+ ,
3.1.1.4: a phosphatidylcholine + H2O → a 2-lyso-phosphatidylcholine + α-linolenate ,
3.1.1.5: a 1-lysophosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+ ,
3.1.1.7: acetylcholine + H2O → acetate + choline + H+ ,
3.1.1.8: an acylcholine + H2O → choline + a carboxylate + H+ ,
3.1.1.13: a steryl-ester + H2O → a sterol + a fatty acid + H+ ,
3.1.1.17: D-glucono-1,5-lactone + H2O → D-gluconate + H+ ,
3.1.1.23: a 1-monoglyceride + H2O → a fatty acid + glycerol + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.1.32: a phosphatidylcholine + H2O → a 1-lysophosphatidylcholine + a fatty acid + H+ ,
3.1.1.34/3.1.1.79: a 1,2-diglyceride + H2O → a 2-monoglyceride + a fatty acid + H+ ,
3.1.1.34: a triacyl-sn-glycerol + H2O = a carboxylate + a 1,2-diacyl-sn-glycerol + H+ ,
3.1.1.45: trans-dienelactone + H2O → 2-maleylacetate + H+ ,
3.1.1.45: cis-dienelactone + H2O → 2-maleylacetate + H+ ,
3.1.1.47: a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O → acetate + a 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + H+ ,
3.1.1.52: an L-1-phosphatidyl-inositol + H2O → 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H+ ,
3.1.1.53: N-acetyl-4-O-acetylneuraminate + H2O → N-acetylneuraminate + acetate + H+ ,
3.1.1.56: 4-methylumbelliferyl acetate + H2O → acetate + 4-methylumbelliferone + H+ ,
3.1.1.77: a 3-(acyloxy)acyl group of bacterial toxin + H2O → a 3-hydroxyacyl group of bacterial toxin + a fatty acid + H+ ,
3.1.1.79: a 2-monoglyceride + H2O → glycerol + a fatty acid + H+ ,
3.1.1.89: a [phosphatase 2A protein] C-terminal L-leucine methyl ester + H2O → a [phosphatase 2A protein] C-terminal L-leucine + methanol + H+ ,
3.1.1.93: mycophenolic acid O-acyl-glucuronide + H2O → mycophenolate + D-glucopyranuronate + H+ ,
3.1.1.-: [heparan sulfate]-N-acetyl-α-D-glucosamine + H2O → [heparan sulfate]-α-D-glucosamine + acetate + H+ ,
3.1.2.1: acetyl-CoA + H2O → acetate + coenzyme A + H+ ,
3.1.2.2: decanoyl-CoA + H2O → decanoate + coenzyme A + H+ ,
3.1.2.2: a 2,3,4-saturated fatty acyl CoA + H2O → a 2,3,4-saturated fatty acid + coenzyme A + H+ ,
3.1.2.2: lauroyl-CoA + H2O → laurate + coenzyme A + H+ ,
3.1.2.2: eicosapentaenoyl-CoA + H2O → icosapentaenoate + coenzyme A + H+ ,
3.1.2.2: myristoyl-CoA + H2O → myristate + coenzyme A + H+ ,
3.1.2.2: arachidoyl-CoA + H2O → arachidate + coenzyme A + H+ ,
3.1.2.2: palmitoyl-CoA + H2O → palmitate + coenzyme A + H+ ,
3.1.2.2: stearoyl-CoA + H2O → stearate + coenzyme A + H+ ,
3.1.2.3: succinyl-CoA + H2O → succinate + coenzyme A + H+ ,
3.1.2.4: 3-hydroxypropanoyl-CoA + H2O → 3-hydroxypropanoate + coenzyme A + H+ ,
3.1.2.4: 3-hydroxy-isobututanoyl-CoA + H2O → 3-hydroxy-isobutyrate + coenzyme A + H+ ,
3.1.2.4: (S)-3-hydroxy-isobutanoyl-CoA + H2O → (S)-3-hydroxy-isobutanoate + coenzyme A + H+ ,
3.1.2.6: S-(2-hydroxyacyl)glutathione + H2O → glutathione + a 2-hydroxy carboxylate ,
3.1.2.6: (R)-S-lactoylglutathione + H2O → glutathione + (R)-lactate + H+ ,
3.1.2.10: formyl-CoA + H2O → formate + coenzyme A + H+ ,
3.1.2.12: S-formylglutathione + H2O → formate + glutathione + H+ ,
3.1.2.20: an acyl-CoA + H2O → a carboxylate + coenzyme A + H+ ,
3.1.2.23: 4-hydroxybenzoyl-CoA + H2O → 4-hydroxybenzoate + coenzyme A + H+ ,
3.1.2.27: choloyl-CoA + H2O → cholate + coenzyme A + H+ ,
3.1.2.-: oleoyl-CoA + H2O → oleate + coenzyme A + H+ ,
3.1.2.-: 3-trans,5-cis-tetradecadienoyl-CoA + H2O → (3E,5Z)-tetradecadienoate + coenzyme A + H+ ,
3.1.3.1: a phosphate monoester + H2O → an alcohol + phosphate ,
3.1.3.2: a phosphate monoester + H2O → an alcohol + phosphate ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.4: a 1,2-diacyl-sn-glycerol 3-phosphate + H2O → a 1,2-diacyl-sn-glycerol + phosphate ,
3.1.3.5: AMP + H2O → adenosine + phosphate ,
3.1.3.5: β-nicotinamide D-ribonucleotide + H2O → 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
3.1.3.5: IMP + H2O → inosine + phosphate ,
3.1.3.5: UMP + H2O → uridine + phosphate ,
3.1.3.5: a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.5: GMP + H2O → guanosine + phosphate ,
3.1.3.5: XMP + H2O → xanthosine + phosphate ,
3.1.3.7: adenosine 3',5'-bisphosphate + H2O → AMP + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.13: 2,3-diphospho-D-glycerate + H2O → 3-phospho-D-glycerate + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.25: 1D-myo-inositol 4-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 2-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 3-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: a myo-inositol monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 6-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 5-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.27: an L-1-phosphatidylglycerol-phosphate + H2O → an L-1-phosphatidyl-glycerol + phosphate ,
3.1.3.29: N-acetyl-β-neuraminate 9-phosphate + H2O → N-acetyl-β-neuraminate + phosphate ,
3.1.3.29: an N-acyl-β-neuraminate 9-phosphate + H2O → an N-acyl-β-neuraminate + phosphate ,
3.1.3.36: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate ,
3.1.3.46: β-D-fructose 2,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.56: D-myo-inositol (1,3,4,5)-tetrakisphosphate + H2O → D-myo-inositol (1,3,4)-trisphosphate + phosphate ,
3.1.3.56: D-myo-inositol (1,4,5)-trisphosphate + H2O → D-myo-inositol (1,4)-bisphosphate + phosphate ,
3.1.3.57: D-myo-inositol (1,4)-bisphosphate + H2O → 1D-myo-inositol 4-monophosphate + phosphate ,
3.1.3.57: D-myo-inositol (1,3,4)-trisphosphate + H2O → D-myo-inositol (3,4)-bisphosphate + phosphate ,
3.1.3.58: D-glucopyranose 6-phosphate + H2O → D-glucopyranose + phosphate ,
3.1.3.58: β-D-glucose 6-phosphate + H2O → β-D-glucose + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,3,5,6) pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → a D myo-inositol penta kis phosphate + phosphate ,
3.1.3.62: D-myo-inositol (1,3,4,5)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate ,
3.1.3.62/3.1.3.72: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → 1D-myo-inositol (1,2,3,4,6)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,3,4,5)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,4,5,6)-pentakisphosphate + phosphate ,
3.1.3.64: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.66: D-myo-inositol (3,4)-bisphosphate + H2O → 1D-myo-inositol 3-monophosphate + phosphate ,
3.1.3.66: D-myo-inositol (1,3,4)-trisphosphate + H2O → D-myo-inositol (1,3)-bisphosphate + phosphate ,
3.1.3.66: a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate ,
3.1.3.67: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + phosphate ,
3.1.3.67: a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate ,
3.1.3.74: pyridoxal 5'-phosphate + H2O → pyridoxal + phosphate ,
3.1.3.74: pyridoxamine 5'-phosphate + H2O → pyridoxamine + phosphate ,
3.1.3.75: phosphoryl-ethanolamine + H2O → ethanolamine + phosphate ,
3.1.3.75: phosphocholine + H2O → choline + phosphate ,
3.1.3.77: 5-(methylthio)-2,3-dioxopentyl 1-phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate + H+ ,
3.1.3.78: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate ,
3.1.3.80: 2,3-diphospho-D-glycerate + H2O → 2-phospho-D-glycerate + phosphate ,
3.1.3.84: ADP ribose 1''-phosphate + H2O → ADP-D-ribose + phosphate ,
3.1.3.86: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate ,
3.1.3.87: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl 1-phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate ,
3.1.3.91: CMP + H2O → cytidine + phosphate ,
3.1.3.95: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate ,
3.1.3.-: D-myo-inositol (1,4,5,6)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate ,
3.1.3.-: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (1,4,5,6)-tetrakisphosphate + phosphate ,
3.1.3.-: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.-: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate ,
3.1.3.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (3,4,5,6)-tetrakisphosphate + phosphate ,
3.1.4.1: an oligonucleotide + H2O → an oligonucleotide + a nucleoside 5'-monophosphate ,
3.1.4.3: a phosphatidylcholine + H2O → phosphocholine + a 1,2-diacyl-sn-glycerol + H+ ,
3.1.4.4: a phosphatidylcholine + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + choline + H+ ,
3.1.4.11: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1,2-diacyl-sn-glycerol + D-myo-inositol (1,4,5)-trisphosphate + H+ ,
3.1.4.11: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → a 1,2-diacyl-sn-glycerol + D-myo-inositol (1,4)-bisphosphate + H+ ,
3.1.4.12: a sphingomyelin + H2O → a ceramide + phosphocholine + H+ ,
3.1.4.17: a cyclic 3',5'-nucleoside monophosphate + H2O → a nucleoside 5'-monophosphate + H+ ,
3.1.4.35: cyclic-GMP + H2O → GMP + H+ ,
3.1.4.37: guanosine 2',3'-cyclic monophosphate + H2O → guanosine 2'-monophosphate + H+ ,
3.1.4.37: adenosine 2',3'-cyclic monophosphate + H2O → adenosine 2'-monophosphate + H+ ,
3.1.4.37: uridine 2'3'-cyclic monophosphate + H2O → uridine 2'-monophosphate + H+ ,
3.1.4.37: a 2',3'-cyclic nucleoside phosphate + H2O → a nucleoside 2'-phosphate + H+ ,
3.1.4.37: cytidine 2',3'-cyclic monophosphate + H2O → cytidine 2'-monophosphate + H+ ,
3.1.4.44: sn-glycero-3-phospho-1-inositol + H2O → myo-inositol + sn-glycerol 3-phosphate + H+ ,
3.1.4.45: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O → glycoprotein-phospho-D-mannose + N-acetyl-β-D-glucosamine + H+ ,
3.1.4.46: a glycerophosphodiester + H2O → an alcohol + sn-glycerol 3-phosphate + H+ ,
3.1.4.50: 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + 1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + H+ ,
3.1.4.54: an N-acylphosphatidylethanolamine + H2O → an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ ,
3.1.4.-: ADP ribose 1'',2''-cyclic phosphate + H2O → ADP ribose 1''-phosphate + H+ ,
3.1.6.1: a phenol sulfate + H2O → a phenol + sulfate + H+ ,
3.1.6.2: 3-β-hydroxyandrost-5-en-17-one 3-sulfate + H2O → sulfate + dehydroepiandrosterone + 3 H+ ,
3.1.6.4: [keratan]-galactose 6'-sulfate + H2O → [keratan]-galactose + sulfate + H+ ,
3.1.6.4: [chondroitin]-6-O-sulfo-N-acetylgalactosamine + H2O → [chondroitin]-N-acetyl-galactosamine + sulfate + H+ ,
3.1.6.8: a cerebroside 3-sulfate + H2O → a cerebroside + sulfate + H+ ,
3.1.6.12: [chondroitin]-4-O-sulfo-N-acetylgalactosamine + H2O → [chondroitin]-N-acetyl-galactosamine + sulfate + H+ ,
3.1.6.13: [dermatan-sulfate]-2-O-sulfo-α-L-iduronate + H2O → [dermatan]-α-L-iduronate + sulfate + 2 H+ ,
3.1.6.13: [heparan-sulfate]-2-O-sulfo-α-L-iduronate + H2O → [heparan-sulfate]-α-L-iduronate + sulfate + H+ ,
3.1.6.14: [heparan sulfate]-α-N-acetyl-D-glucosamine 6-O-sulfate + H2O → [heparan sulfate]-N-acetyl-α-D-glucosamine + sulfate + H+ ,
3.1.6.14: [keratan sulfate]-α-N-acetyl-D-glucosamine 6-O-sulfate + H2O → [keratan sulfate]-α-N-acetyl-D-glucosamine + sulfate + H+ ,
3.1.6.18: [heparan-sulfate]-2-O-sulfo-β-D-glucuronate + H2O → [heparan-sulfate]-β-D-glucuronate + sulfate + H+ ,
3.1.6.18: [chondroitin-sulfate]-2-O-sulfo-β-D-glucuronate + H2O → [chondroitin-sulfate]-β-D-glucuronate + sulfate + 2 H+ ,
3.1.8.1: paraoxon + H2O → diethylphosphate + 4-nitrophenol + 2 H+ ,
3.1.8.1: an aryl dialkyl phosphate + H2O → a dialkyl phosphate + a phenol ,
3.1.8.1: amino-parathion + H2O → diethylthiophosphate + 4-aminophenol + H+ ,
3.1.8.1: methyl parathion + H2O → 4-nitrophenol + dimethylthiophosphate + 2 H+ ,
3.1.8.1: parathion + H2O → diethylthiophosphate + 4-nitrophenol + 2 H+ ,
3.1.11.1: DNAn + H2O → (deoxynucleotides)(n-1) + a 2'-deoxyribonucleoside 5'-monophosphate ,
3.1.11.-: DNAn + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.1: RNase II degradation substrate mRNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.3: an oligonucleotide + H2O → n a nucleoside 5'-monophosphate ,
3.1.13.4: a mRNA with poly(A) tail + n H2O → an mRNA + n AMP ,
3.1.21.1: a double stranded DNA + 2n H2O → n a 5'-phosphooligonucleotide + n a 5' phosphodinucleotide ,
3.1.22.1: a double stranded DNA + H2O → a 3' phosphooligonucleotide + a 5'-hydroxyoligonucleotide ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.11: a tRNA precursor + H2O → mature tRNA + a single-stranded oligoribonucleotide ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.27.1: RNA + H2O → a nucleoside 3'-phosphate + a 3' phosphooligonucleotide ,
3.1.27.5: RNA + H2O → a nucleoside 3'-phosphate + a 3' phosphooligonucleotide ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → n a 1,4-α-D-glucan ,
3.2.1.1: starch + n H2O → a large-branched glucan ,
3.2.1.1: starch + H2O → maltose + glucose ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → a 1,4-α-D-glucan + maltohexaose ,
3.2.1.3: a debranched limit dextrin + n H2O → n β-D-glucose ,
3.2.1.3: {6-α-D-(1,4-α-D-glucano)-glucan}n + H2O → {6-α-D-(1,4-α-D-glucano)-glucan}n-1 + β-D-glucose ,
3.2.1.10: β-isomaltose + H2O → α-D-glucose + D-glucopyranose ,
3.2.1.14: chitin + n H2O → n a chitodextrin ,
3.2.1.17: a peptidoglycan + H2O → a N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol + N-acetyl-D-glucosamine ,
3.2.1.18: a sialyloligosaccharide + H2O → an oligosaccharide + N-acetylneuraminate ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.20: α-maltose + H2O → 2 α-D-glucose ,
3.2.1.20: (1,4-α-D-glucosyl)(n) + H2O → (1,4-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.21: a β-D glucoside + H2O → a non glucosylated glucose acceptor + β-D-glucose ,
3.2.1.21: linamarin + H2O → acetone cyanohydrin + β-D-glucose ,
3.2.1.22: an α-D-galactoside + H2O → α-D-galactose + a non galactosylated galactose acceptor ,
3.2.1.22: melibiose + H2O → α-D-galactose + β-D-glucose ,
3.2.1.22: stachyose + H2O → raffinose + α-D-galactose ,
3.2.1.23: XXLG xyloglucan oligosaccharide + H2O → XXXG xyloglucan oligosaccharide + β-D-galactose ,
3.2.1.23: a β-D-galactoside + H2O → a non galactosylated galactose acceptor + β-D-galactose ,
3.2.1.23: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.23: XLLG xyloglucan oligosaccharide + 2 H2O → XXXG xyloglucan oligosaccharide + 2 β-D-galactose ,
3.2.1.23: 3'-ketolactose + H2O → 3-keto-β-D-galactose + β-D-glucose ,
3.2.1.23: XLXG xyloglucan oligosaccharide + H2O → XXXG xyloglucan oligosaccharide + β-D-galactose ,
3.2.1.24: an α-D-mannoside + H2O → α-D-mannose + a non glycosylated sugar acceptor ,
3.2.1.25: a β-D-mannoside + H2O → β-D-mannose + a non glycosylated sugar acceptor ,
3.2.1.28: α,α-trehalose + H2O → β-D-glucose + α-D-glucose ,
3.2.1.31: a β-D-glucuronoside + H2O → D-glucopyranuronate + an alcohol ,
3.2.1.33: a limit dextrin + H2O → maltotetraose + a debranched limit dextrin ,
3.2.1.33: a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose ,
3.2.1.35: dermatan sulfate + n H2O → n dermatan sulfate disaccharide ,
3.2.1.35: hyaluronan + n H2O → n hyaluronate ,
3.2.1.35: chondroitin sulfate + n H2O → n chondroitin sulfate disaccharide ,
3.2.1.37: a (1->4)-β-D-xylan oligosaccharide + n H2O → n β-D-xylopyranose ,
3.2.1.44: a fucoidan + H2O → fucose + a fucose sulfate + an oligosaccharide ,
3.2.1.45: a D-glucosyl-N-acylsphingosine + H2O → an N-acylsphingosine + β-D-glucose ,
3.2.1.46: a D-galactosyl-N-acylsphingosine + H2O → an N-acylsphingosine + β-D-galactose ,
3.2.1.48: sucrose + H2O → β-D-fructofuranose + α-D-glucose ,
3.2.1.49: N-acetyl-α-D-glucosaminyl-[glycoprotein] + H2O → N-acetyl-α-D-galactosamine + a glycoprotein ,
3.2.1.50: an N-acetyl-α-D-glucosaminide + H2O → N-acetyl-α-D-glucosamine + a non glycosylated sugar acceptor ,
3.2.1.51: α-L-fucoside + H2O → L-fucopyranose + an alcohol ,
3.2.1.52: chitotriose + H2O → N,N'-diacetylchitobiose + N-acetyl-D-glucosamine ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.1.52: N,N'-diacetylchitobiose + H2O → 2 N-acetyl-D-glucosamine ,
3.2.1.52: an N-acetyl-β-D-galactosalaminyl-[glycan] + H2O → a glycan + N-acetyl-β-D-galactosamine ,
3.2.1.52: an N-acetyl-β-D-hexosaminide + H2O → an N-acetyl-β-D-hexosamine + an alcohol ,
3.2.1.62: glycosyl-N-acylsphingosine + H2O → a ceramide + a sugar ,
3.2.1.76: [dermatan]-α-L-iduronate + H2O → α-L-iduronate + [dermatan]-N-acetyl-D-galactosamine ,
3.2.1.84: (1,3-α-D-glucosyl)(n) + H2O → (1,3-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.96: a glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine + H2O → N-acetyl-D-glucosamine-asparagine + a glycopeptide-D-mannosyl-N4-N-acetyl-D-glucosamine ,
3.2.1.106: Glc3Man9GlcNAc2 + H2O → Glc2Man9GlcNAc2 + D-glucopyranose ,
3.2.1.108: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.113: a (mannosyl)9-(N-acetylglucosaminyl)2 + H2O → a (mannosyl)8-(N-acetylglucosaminyl)2 + D-mannose ,
3.2.1.114: a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan + 2 H2O → N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine + 2 α-D-mannose ,
3.2.1.127: an immunoglobulin G glycopeptide + H2O → fragments of immunoglobuline G glycopeptide + α-L-fucopyranose ,
3.2.1.130: a GlcMan9(GlcNAc)2-glycoprotein + H2O → a GlcMan8(GlcNAc)2-glycoprotein + D-glucosyl-α(1→3)- mannose ,
3.2.1.143: poly(ADP-D-ribose)(n) + H2O → poly(ADP-D-ribose)(n-1) + ADP-D-ribose ,
3.2.1.166: heparan sulfate containing a glucuronate--N,3-O-disulfo-D-glucosamine disaccharide + n H2O → n short heparan sulfate fragments ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-L-threonine-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [protein]-L-threonine ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-L-serine-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [protein]-L-serine ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) ,
3.2.1.170: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate + H2O → α-D-mannose 6-phosphate + D-glycerate ,
3.2.1.183: UDP-N-acetyl-α-D-glucosamine + H2O → N-acetyl-α-D-mannosamine + UDP + H+ ,
3.2.1.-: a long-linear glucan + n H2O → a linear malto-oligosaccharide ,
3.2.2.6: NAD+ + H2O → ADP-D-ribose + nicotinamide + H+ ,
3.2.2.19: Nω-(ADP-D-ribosyl)-L-arginine + H2O → ADP-D-ribose + L-arginine ,
3.2.2.19: a protein-Nω-(ADP-D-ribosyl)-L-arginine + H2O → ADP-D-ribose + a [protein]-L-arginine ,
3.2.2.21: an alkylated DNA + H2O → DNAn + an alkylated nucleobase ,
3.2.2.29: a DNA containing a mismatch + H2O → a DNA containing an apyrimidinic site + thymine ,
3.3.1.1: S-adenosyl-L-homocysteine + H2O → L-homocysteine + adenosine ,
3.3.2.6: leukotriene A4 + H2O → leukotriene B4 ,
3.3.2.9: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol ,
3.3.2.10: an epoxide + H2O = a glycol ,
3.3.2.-: 4(5)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D4 ,
3.3.2.-: 7S-hydroperoxy,17R-H-docosahexaenoate → 7(8)-epoxy-17R-H-docosahexaenoate + H2O ,
3.3.2.-: 7(8)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D2 ,
3.3.2.-: 4S-hydroperoxy,17S-H-docosahexaenoate → 4(5)-epoxy-17S-H-docosahexaenoate + H2O ,
3.3.2.-: 4S-hydroperoxy,17R-H-docosahexaenoate → 4(5)-epoxy-17R-H-docosahexaenoate + H2O ,
3.3.2.-: 7(8)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D1 ,
3.3.2.-: 4(5)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D3 ,
3.3.2.-: 7S-hydroperoxy,17S-H-docosahexaenoate → 7(8)-epoxy-17S-H-docosahexaenoate + H2O ,
3.3.2.-: 4(5)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D3 ,
3.3.2.-: 7(8)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D2 ,
3.3.2.-: 4(5)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D4 ,
3.3.2.-: 7(8)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D1 ,
3.4.11.2: 4-hydroxy-2-nonenal-[Cys-Gly] conjugate + H2O → 4-hydroxy-2-nonenal-[L-Cys] conjugate + glycine ,
3.4.11.2: a polypeptide + H2O → a polypeptide + an L-amino acid ,
3.4.11.2: a [Cys-Gly]-S-conjugate + H2O → an L-cysteine-S-conjugate + glycine ,
3.4.11.3: a protein + H2O → a peptide + a peptide ,
3.4.11.5: an N-terminal [protein]-L-proline + H2O → a peptide + L-proline ,
3.4.11.6: a protein + H2O → a peptide + a peptide ,
3.4.11.7: a [protein] N-terminal L-glutamate + H2O → L-glutamate + a protein + H+ ,
3.4.11.9: a peptide + H2O → a standard α amino acid + a peptide ,
3.4.11.14: amino acids(n) + H2O → amino acids(n-1) + a standard α amino acid ,
3.4.11.18: a peptide with N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.11.21: a protein + H2O → a peptide + a peptide ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.13.18: L-alanyl-L-histidine + H2O → L-alanine + L-histidine ,
3.4.13.18: a dipeptide + H2O → 2 a standard α amino acid ,
3.4.13.18: L-cysteinyl-glycine + H2O → L-cysteine + glycine ,
3.4.13.18: L-alanyl-L-aspartate + H2O → L-alanine + L-aspartate ,
3.4.13.19: a dipeptide + H2O → 2 amino acids ,
3.4.13.19: leukotriene-D4 + H2O → glycine + leukotriene-E4 ,
3.4.13.20: a dipetide with L-histidine at the C-terminal + H2O → a standard α amino acid + L-histidine ,
3.4.13.21: a dipetide with L-aspartate at the N-terminal + H2O → L-aspartate + a standard α amino acid ,
3.4.14.1: a peptide + n H2O → n+1 a dipeptide ,
3.4.14.2: an oligopeptide + H2O → a dipeptide + a peptide ,
3.4.14.4: an oligopeptide + H2O → a peptide + a dipeptide ,
3.4.14.5: a polypeptide + H2O → a dipeptide + a peptide ,
3.4.14.9: a polypeptide + H2O → a peptide + a tripeptide ,
3.4.14.10: a polypeptide + H2O → a peptide + a tripeptide ,
3.4.15.1: an oligopeptide + H2O → a dipeptide + a peptide ,
3.4.16.2: an oligopeptide + H2O → a peptide + a standard α amino acid ,
3.4.16.5: a peptide + H2O → a peptide + a standard α amino acid ,
3.4.16.6: a protein + H2O → a basic amino acid + a protein ,
3.4.17.11: folate + H2O → pteroate + a glutamate ,
3.4.17.12: a protein + H2O → a protein + an α amino acid ,
3.4.17.15: a peptide + H2O → a peptide + an aromatic amino acid ,
3.4.17.20: a peptide + H2O → a peptide + a basic amino acid ,
3.4.17.21: a peptide + H2O → a peptide + L-glutamate ,
3.4.17.22: a peptide + H2O → a basic amino acid + a peptide ,
3.4.18.1: a protein + H2O → a peptide + a peptide ,
3.4.19.5: a protein + H2O → a protein + L-aspartate ,
3.4.19.6: a 5-oxoprolyl-peptide + H2O → 5-oxoproline + a peptide ,
3.4.19.9: tetrahydropteroyl-[γ-Glu](n) + H2O → tetrahydropteroyl-[γ-Glu](n-1) + L-glutamate ,
3.4.19.9: a glutathione-toxin conjugate + H2O → a [Cys-Gly]-S-conjugate + L-glutamate ,
3.4.19.9: 4-hydroxy-2-nonenal-glutathione conjugate + H2O → 4-hydroxy-2-nonenal-[Cys-Gly] conjugate + L-glutamate ,
3.4.19.12: a ubiquitin C-terminal thioester + H2O → a ubiquitin + a thiol ,
3.4.19.13: glutathione + H2O → L-cysteinyl-glycine + L-glutamate ,
3.4.21.1: a protein + H2O → a peptide + a peptide ,
3.4.21.2: a protein + H2O → a peptide + a peptide ,
3.4.21.4: a protein + H2O → a peptide + a peptide ,
3.4.21.5: a fibrinogen + H2O → a fibrin + a fibrinopeptide A + a fibrinopeptide B ,
3.4.21.6: a prothrombin + H2O → a thrombin + a peptide + a peptide ,
3.4.21.7: a fibrin + H2O → n a peptide ,
3.4.21.9: trypsinogen + H2O → trypsin + a peptide ,
3.4.21.10: a protein + H2O → a peptide + a peptide ,
3.4.21.20: a protein + H2O → a peptide + a peptide ,
3.4.21.21: a factor X + H2O → a factor Xa + a factor Xa ,
3.4.21.22: a factor X + H2O → a factor Xa + a factor Xa ,
3.4.21.26: a protein + H2O → a peptide + a peptide ,
3.4.21.27: a factor IX + H2O → a factor IXa + a factor IXa ,
3.4.21.34: a protein + H2O → a peptide + a peptide ,
3.4.21.35: a protein + H2O → a peptide + a peptide ,
3.4.21.36: a protein + H2O → a peptide + a peptide ,
3.4.21.37: a protein + H2O → a peptide + a peptide ,
3.4.21.38: a factor VII + H2O → a factor VIIa + a factor VIIa ,
3.4.21.38: a factor XI + H2O → a factor XIa ,
3.4.21.39: a protein + H2O → a peptide + a peptide ,
3.4.21.41: complement subcomponent C1s + H2O → activated complement subcomponent C1s ,
3.4.21.43/3.4.21.47: a complement 5 α chain + H2O → a C5a anaphylatoxin + a complement C5 α' chain ,
3.4.21.45: complement component protein C3b + H2O → complement component protein C3c + complement component protein C3d ,
3.4.21.45: complement component protein C4b + H2O → complement component protein C4c + complement component protein C4d ,
3.4.21.46: complement factor B + H2O → complement factor Ba + complement factor Bb ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.59: a protein + H2O → a peptide + a peptide ,
3.4.21.68: a plasminogen + H2O → a plasmin ,
3.4.21.69: a factor Va + H2O → n a peptide ,
3.4.21.69: a factor VIIIa + H2O → n a peptide ,
3.4.21.70: a protein + H2O → a peptide + a peptide ,
3.4.21.71: a protein + H2O → a peptide + a peptide ,
3.4.21.73: a plasminogen + H2O → a plasmin ,
3.4.21.75: a protein precursor + H2O → a mature protein ,
3.4.21.76: a protein + H2O → a peptide + a peptide ,
3.4.21.77: semenogelin-1 + H2O → n fragments of semenogelin-1 ,
3.4.21.78: a protein + H2O → a peptide + a peptide ,
3.4.21.79: a protein + H2O → a peptide + a peptide ,
3.4.21.83: an oligopeptide + H2O → a peptide + a peptide ,
3.4.21.89: a peptide with a leader sequence + H2O → a peptide + a leader sequence ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.93: a protein + H2O → a peptide + a peptide ,
3.4.21.94: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a cleaved lipoprotein signal peptide + H2O → n a peptide ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.22.1: a protein + H2O → a peptide + a peptide ,
3.4.22.15: a protein + H2O → a peptide + a peptide ,
3.4.22.16: a protein + H2O → a peptide + a peptide ,
3.4.22.27: a protein + H2O → a peptide + a peptide ,
3.4.22.34: a protein + H2O → a peptide + a peptide ,
3.4.22.36: pro-interleukin-1β + H2O → mature pro-interleukin-1β ,
3.4.22.38: a protein + H2O → a peptide + a peptide ,
3.4.22.40: a bleomycin + H2O → a deamido-bleomycin ,
3.4.22.41: a protein + H2O → a peptide + a peptide ,
3.4.22.42: a protein + H2O → a peptide + a peptide ,
3.4.22.43: a protein + H2O → a peptide + a peptide ,
3.4.23.1: a protein + H2O → a peptide + a peptide ,
3.4.23.3: a protein + H2O → a peptide + a peptide ,
3.4.23.5: a protein + H2O → a peptide + a peptide ,
3.4.23.15: an angiotensinogen + H2O → angiotensin I + a cleaved angiotensinogen ,
3.4.23.34: a protein + H2O → a peptide + a peptide ,
3.4.23.49: a protein + H2O → a peptide + a peptide ,
3.4.24.3: a collagen + H2O → n a peptide ,
3.4.24.7: a collagen + H2O → a peptide + a peptide ,
3.4.24.11: a protein + H2O → a peptide + a peptide ,
3.4.24.14: a procollagen + H2O → a cleaved procollagen + a peptide ,
3.4.24.15: a protein + H2O → a peptide + a peptide ,
3.4.24.16: an oligopeptide + H2O → a peptide + a peptide ,
3.4.24.17: a protein + H2O → a peptide + a peptide ,
3.4.24.18: a protein + H2O → a peptide + a peptide ,
3.4.24.19: a procollagen + H2O → C-terminal propeptides of procollagen + a peptide ,
3.4.24.22: a protein + H2O → a peptide + a peptide ,
3.4.24.23: a protein + H2O → a peptide + a peptide ,
3.4.24.24: a protein + H2O → a peptide + a peptide ,
3.4.24.34: a protein + H2O → a peptide + a peptide ,
3.4.24.35: a protein + H2O → a peptide + a peptide ,
3.4.24.55: a protein + H2O → n a peptide ,
3.4.24.56: a polypeptide + H2O → n a peptide ,
3.4.24.57: a O-sialoglycoprotein + H2O → n a peptide ,
3.4.24.59: mitochondrial intermediate protein + H2O → an octapeptide + a mature protein ,
3.4.24.61: a protein + H2O → a peptide + a peptide ,
3.4.24.64: a mitochondrial preprotein including a mitochondrial targeting sequence + H2O → a processed mitochondrial protein + a peptide ,
3.4.24.65: a protein + H2O → n a peptide ,
3.4.24.71: big endothelin + H2O → endothelin 1 + a peptide ,
3.4.24.81: a protein + H2O → 2 a peptide ,
3.4.24.82: aggrecan + H2O → n an aggrecan cleavage product ,
3.4.24.84: a protein S-farnesyl-L-cysteine + H2O → a [protein] c-terminal S-farnesyl-L-cysteine + a peptide ,
3.5.1.6: 3-ureido-isobutyrate + H2O + 2 H+ → (R)-3-amino-2-methylpropanoate + ammonium + CO2 ,
3.5.1.6: 3-ureidopropionate + H2O + 2 H+ → β-alanine + ammonium + CO2 ,
3.5.1.9: N-formylkynurenine + H2O → L-kynurenine + formate + H+ ,
3.5.1.10: an N10-formyl-tetrahydrofolate + H2O → a tetrahydrofolate + formate + H+ ,
3.5.1.12: biotin amide + H2O = ammonium + biotin ,
3.5.1.14: an N-acylated aliphatic-L-amino acid + H2O = a carboxylate + an aliphatic L-amino acid ,
3.5.1.15: an N-acyl-L-aspartate + H2O → L-aspartate + a carboxylate ,
3.5.1.15: N-acetyl-L-aspartate + H2O = L-aspartate + acetate ,
3.5.1.23: an α hydroxyphytoceramide + H2O ↔ phytosphingosine + a hydroxy fatty acid ,
3.5.1.23: a ceramide + H2O = a sphingoid base + a fatty acid ,
3.5.1.23: an N-acylsphingosine + H2O → sphingosine + a fatty acid ,
3.5.1.25: N-acetyl-D-galactosamine 6-phosphate + H2O = acetate + D-galactosamine 6-phosphate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.26: N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O → N-acetyl-β-glucosaminylamine + L-aspartate + H+ ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O = N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala ,
3.5.1.38: L-asparagine + H2O → L-aspartate + ammonium ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.52: a [protein]-N4-(N-acetyl-β-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-β-glucosaminylamine + a [protein]-L-aspartate + H+ ,
3.5.1.63: 4-acetamidobutanoate + H2O → 4-aminobutanoate + acetate ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O = a [protein] N-terminal L-methionine + formate ,
3.5.1.89: a 6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O = 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate ,
3.5.1.92: pantetheine + H2O = (R)-pantothenate + cysteamine ,
3.5.1.99: oleamide + H2O = oleate + ammonium ,
3.5.1.99: anandamide + H2O → arachidonate + ethanolamine ,
3.5.1.109: an N-acyl-sphingosylphosphorylcholine + H2O → a fatty acid + sphingosylphosphorylcholine ,
3.5.1.109: a D-glucosyl-N-acylsphingosine + H2O = a fatty acid + D-glucosyl-sphingosine ,
3.5.1.111: 2-oxoglutaramate + H2O → 2-oxoglutarate + ammonium ,
3.5.2.2: 5,6-dihydrouracil + H2O → 3-ureidopropionate + H+ ,
3.5.2.2: 5,6-dihydrothymine + H2O → 3-ureido-isobutyrate + H+ ,
3.5.2.2: hydantoin + H2O = N-carbamoylglycine + H+ ,
3.5.2.3: (S)-dihydroorotate + H2O ← N-carbamoyl-L-aspartate + H+ ,
3.5.2.7: 4-imidazolone-5-propionate + H2O → N-formimino-L-glutamate ,
3.5.2.9: 5-oxoproline + ATP + 2 H2O → L-glutamate + ADP + phosphate + H+ ,
3.5.3.1: L-arginine + H2O → urea + L-ornithine ,
3.5.3.4: allantoate + H2O = S-ureidoglycolate + urea ,
3.5.3.11: agmatine + H2O → urea + putrescine ,
3.5.3.18: N6,N6-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline ,
3.5.4.3: guanine + H+ + H2O → ammonium + xanthine ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.5: cytidine + H+ + H2O → uridine + ammonium ,
3.5.4.5: 2'-deoxycytidine + H+ + H2O → 2'-deoxyuridine + ammonium ,
3.5.4.9: a 5,10-methenyltetrahydrofolate + H2O ↔ an N10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ← 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.12: dCMP + H+ + H2O → ammonium + dUMP ,
3.5.4.16: GTP + H2O → formate + 7,8-dihydroneopterin 3'-triphosphate + H+ ,
3.5.4.17: AMP + H+ + H2O → IMP + ammonium ,
3.5.5.1: a nitrile + 2 H2O = a carboxylate + ammonium ,
3.5.5.1: indole-3-acetonitrile + 2 H2O = ammonium + indole-3-acetate ,
3.5.99.6: α-D-glucosamine 6-phosphate + H2O ↔ β-D-fructofuranose 6-phosphate + ammonium ,
3.5.99.10: 2-iminopropanoate + H+ + H2O → pyruvate + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.5: UTP + 2 H2O → UMP + 2 phosphate + 2 H+ ,
3.6.1.5: ATP + 2 H2O → AMP + 2 phosphate + 2 H+ ,
3.6.1.5: a nucleoside triphosphate + 2 H2O → a nucleoside 5'-monophosphate + 2 phosphate + 2 H+ ,
3.6.1.5: CTP + 2 H2O → CMP + 2 phosphate + 2 H+ ,
3.6.1.5: ADP + H2O = AMP + phosphate + H+ ,
3.6.1.6: CDP + H2O → CMP + phosphate + H+ ,
3.6.1.6: a nucleoside diphosphate + H2O = a nucleoside 5'-monophosphate + phosphate + H+ ,
3.6.1.6: UDP + H2O → UMP + phosphate + H+ ,
3.6.1.6: dCDP + H2O → dCMP + phosphate + H+ ,
3.6.1.7: an acyl phosphate + H2O = a carboxylate + phosphate + H+ ,
3.6.1.9: a dinucleotide (nucleic acid) + H2O = 2 a nucleoside 5'-monophosphate + 2 H+ ,
3.6.1.9: NADH + H2O = NMNH + AMP + 2 H+ ,
3.6.1.14: adenosine pentaphosphate + H2O = adenosine tetraphosphate + phosphate + H+ ,
3.6.1.14: adenosine tetraphosphate + H2O = ATP + phosphate + 2 H+ ,
3.6.1.15: UTP + H2O → UDP + phosphate + H+ ,
3.6.1.15: a nucleoside triphosphate + H2O → a nucleoside diphosphate + phosphate + H+ ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.16: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+ ,
3.6.1.17: P1,P4-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP + 2 H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.19: ITP + H2O = IMP + diphosphate + H+ ,
3.6.1.19: dGTP + H2O → dGMP + diphosphate + H+ ,
3.6.1.19: a nucleoside triphosphate + H2O → a nucleoside 5'-monophosphate + diphosphate + H+ ,
3.6.1.21: an ADP-sugar + H2O = AMP + an α-D-aldose 1-phosphate ,
3.6.1.28: thiamin triphosphate + H2O = thiamin diphosphate + phosphate + H+ ,
3.6.1.29: 5',5'''-diadenosine triphosphate + H2O = AMP + ADP + 2 H+ ,
3.6.1.43: dolichyl diphosphate + H2O = a dolichyl phosphate + phosphate + H+ ,
3.6.1.45: a UDP-sugar + H2O → UMP + an α-D-aldose 1-phosphate + 2 H+ ,
3.6.1.52: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: a diphospho-1D-myo-inositol tetrakisphosphate + H2O = D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: a pyrophosphate-containing inositol phosphate + H2O = a myo-inositol-polyphosphate + phosphate ,
3.6.1.52: 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + H2O = 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate + H+ ,
3.6.1.53: ADP-D-ribose + H2O = AMP + D-ribofuranose 5-phosphate + 2 H+ ,
3.6.1.53: CDP-choline + H2O = CMP + phosphocholine + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.56: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate + H+ ,
3.6.1.58: 8-oxo-dGDP + H2O → 8-oxo-dGMP + phosphate + H+ ,
3.6.1.60: 5',5'''-diadenosine pentaphosphate + H2O = adenosine tetraphosphate + AMP + H+ ,
3.6.1.60: 5',5'''-diadenosine hexaphosphate + H2O = adenosine pentaphosphate + AMP + H+ ,
3.6.1.65: dCTP + H2O = dCMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GDP + H2O → 8-oxo-GMP + phosphate + H+ ,
3.6.1.-: 8-oxo-dADP + H2O → 8-oxo-dAMP + phosphate + H+ ,
3.6.3.1: a phospholipid[out] + ATP + H2O → a phospholipid[cytosol] + ADP + phosphate + H+ ,
3.6.3.4: Cu2+[cytosol] + ATP + H2O ↔ Cu2+[golgi lumen] + ADP + phosphate + 2 H+ ,
3.6.3.4: Cu2+[cytosol] + ATP + H2O → Cu2+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[endoplasmic reticulum lumen] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[golgi lumen] + ADP + phosphate + H+ ,
3.6.3.9: 2 K+[extracellular space] + 3 Na+[cytosol] + ATP + H2O → 2 K+[cytosol] + 3 Na+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.10: K+[extracellular space] + ATP + H+[cytosol] + H2O → ADP + K+[cytosol] + phosphate + H+[cytosol] + H+[cytosol] ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.44: a xenobiotic[cytosol] + ATP + H2O ↔ a xenobiotic[extracellular space] + ADP + phosphate ,
3.6.3.49: chloride[out] + ATP + H2O ↔ chloride[cytosol] + ADP + phosphate + H+ ,
3.6.3.-: Cu2+[out] + ATP + H2O ↔ Cu2+[in] + ADP + phosphate + H+ ,
3.6.3.-: Ca2+[in] + ATP + H2O ↔ Ca2+[out] + ADP + phosphate + H+ ,
3.6.4.3: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.4: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.6: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.7: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.12: a double-helix DNA + ATP + H2O → an unwound double-stranded DNA + ADP + phosphate + H+ ,
3.6.4.13: ATP + H2O = ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
3.7.1.2: 4-fumaryl-acetoacetate + H2O → fumarate + acetoacetate + H+ ,
3.7.1.3: L-kynurenine + H2O ← L-alanine + anthranilate + H+ ,
3.7.1.3: 3-hydroxy-L-kynurenine + H2O → 3-hydroxyanthranilate + L-alanine + H+ ,
3.10.1.1: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate ,
3.13.1.-: 3-sulfinopyruvate + H2O → sulfite + pyruvate + H+ ,
4.1.1.4: acetoacetate + H+ → acetone + CO2 ,
4.1.1.6: cis-aconitate + H+ = CO2 + itaconate ,
4.1.1.9: malonyl-CoA + H+ → CO2 + acetyl-CoA ,
4.1.1.15: L-glutamate + H+ → CO2 + 4-aminobutanoate ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.19: L-arginine + H+ → CO2 + agmatine ,
4.1.1.21: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ ← 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 ,
4.1.1.22: L-histidine + H+ = CO2 + histamine ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.25: L-tyrosine + H+ → CO2 + tyramine ,
4.1.1.28: L-dopa + H+ → dopamine + CO2 ,
4.1.1.28: L-tryptophan + H+ → CO2 + tryptamine ,
4.1.1.28: 5-hydroxy-L-tryptophan + H+ → serotonin + CO2 ,
4.1.1.29: 3-sulfinoalanine + H+ → CO2 + hypotaurine ,
4.1.1.32: oxaloacetate + ITP = CO2 + phosphoenolpyruvate + IDP ,
4.1.1.32: oxaloacetate + GTP → CO2 + phosphoenolpyruvate + GDP ,
4.1.1.33: (R)-mevalonate diphosphate + ATP → isopentenyl diphosphate + CO2 + ADP + phosphate ,
4.1.1.34: 3-keto-L-gulonate + H+ → L-xylulose + CO2 ,
4.1.1.35: UDP-α-D-glucuronate + H+ → UDP-α-D-xylose + CO2 ,
4.1.1.36: R-4'-phosphopantothenoyl-L-cysteine + H+ → 4'-phosphopantetheine + CO2 ,
4.1.1.37: uroporphyrinogen-I + 4 H+ = coproporphyrinogen I + 4 CO2 ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → 4 CO2 + coproporphyrinogen III ,
4.1.1.41: (S)-methylmalonyl-CoA + H+ = CO2 + propanoyl-CoA ,
4.1.1.45: aminocarboxymuconate semialdehyde + H+ → CO2 + 2-aminomuconate 6-semialdehyde ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.65: an L-1-phosphatidylserine + H+ = an L-1-phosphatidyl-ethanolamine + CO2 ,
4.1.1.70: (E)-glutaconyl-CoA + H+ ↔ CO2 + crotonyl-CoA ,
4.1.1.84: D-dopachrome + H+ = 5,6-dihydroxyindole + CO2 ,
4.1.1.90: a [protein] 4-carboxy-L-glutamate + vitamin K 2,3-epoxide + H2O = phylloquinone + a [protein]-α-L-glutamate + CO2 + oxygen + H+ ,
4.1.1.94: (S)-ethylmalonyl-CoA + H+ = butanoyl-CoA + CO2 ,
4.1.1.-: a 3-oxoacid + H+ → a methylketone + CO2 ,
4.1.1.-: 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate → acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.13: β-D-fructofuranose 1-phosphate → dihydroxyacetone phosphate + D-glyceraldehyde ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.27: sphinganine 1-phosphate = palmitaldehyde + phosphoryl-ethanolamine ,
4.1.2.30: 17-α-hydroxypregnenolone → dehydroepiandrosterone + acetaldehyde ,
4.1.3.3: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate ,
4.1.3.4: (S)-3-hydroxy-3-methylglutaryl-CoA → acetoacetate + acetyl-CoA ,
4.1.3.6: citrate = acetate + oxaloacetate ,
4.1.3.16: 4-hydroxy-2-oxoglutarate → glyoxylate + pyruvate ,
4.1.3.44: N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine → 4-demethylwyosine37 in tRNAPhe + L-methionine + 5'-deoxyadenosine + CO2 + H2O ,
4.1.99.14: (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA) = thymidylyl-(3'-5')-thymidylate (in DNA) ,
4.1.99.18: GTP → cyclic pyranopterin phosphate + diphosphate ,
4.1.-.-: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA → a 2-methyl branched 2,3,4-saturated fatty aldehyde + formyl-CoA ,
4.1.-.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA → an odd numbered straight chain 2,3,4-saturated fatty aldehyde + formyl-CoA ,
4.2.1.1: carbonic acid = CO2 + H2O ,
4.2.1.1: hydrogen carbonate + H+ = CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.17: OPC8-3-hydroxyacyl-CoA = OPC8-trans-2-enoyl-CoA + H2O ,
4.2.1.17: 2-methyl-3-hydroxybutyryl-CoA ← (E)-2-methylcrotonoyl-CoA + H2O ,
4.2.1.17: (S)-3-hydroxydecanoyl-CoA ← trans-Δ2-decenoyl-CoA + H2O ,
4.2.1.17: (S)-3-hydroxy-isobutanoyl-CoA ← methylacrylyl-CoA + H2O ,
4.2.1.17: OPC4-3-hydroxyacyl-CoA = OPC4-trans-2-enoyl-CoA + H2O ,
4.2.1.17: a (3S)-3-hydroxyacyl-CoA ← a trans-2-enoyl-CoA + H2O ,
4.2.1.17: a (3R)-3-hydroxyacyl-CoA = a cis-2-enoyl-CoA + H2O ,
4.2.1.17: OPC6-3-hydroxyacyl-CoA = OPC6-trans-2-enoyl-CoA + H2O ,
4.2.1.17: 3-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA = 4-coumaryl-CoA + H2O ,
4.2.1.17: 3-hydroxyadipyl-CoA = 2,3-didehydroadipyl-CoA + H2O ,
4.2.1.18: (S)-3-hydroxy-3-methylglutaryl-CoA ← 3-methylglutaconyl-CoA + H2O ,
4.2.1.22: L-homocysteine + L-serine → L-cystathionine + H2O ,
4.2.1.24: 2 5-aminolevulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.46: dTDP-α-D-glucose = dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O ,
4.2.1.47: GDP-α-D-mannose → GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.49: 4-imidazolone-5-propionate ← urocanate + H2O ,
4.2.1.55: (R)-3-hydroxybutanoyl-CoA = crotonyl-CoA + H2O ,
4.2.1.70: D-ribofuranose 5-phosphate + uracil = pseudouridine 5'-phosphate + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.77: trans-3-hydroxy-L-proline = Δ1-pyrroline-2-carboxylate + H2O + H+ ,
4.2.1.93: (S)-NADPHX + ATP = ADP + NADPH + phosphate + H+ ,
4.2.1.93: ATP + (S)-NADHX → ADP + NADH + phosphate + H+ ,
4.2.1.96: 4α-hydroxy-tetrahydrobiopterin → 7,8-dihydrobiopterin + H2O ,
4.2.1.107: (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + H2O → (24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA ,
4.2.1.107: (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA ← (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + H2O ,
4.2.1.109: 5-methylthioribulose 1-phosphate → 5-(methylthio)-2,3-dioxopentyl 1-phosphate + H2O ,
4.2.1.119: a (3R)-3-hydroxyacyl-CoA ↔ a trans-2-enoyl-CoA + H2O ,
4.2.1.134: a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H2O ,
4.2.1.150: (S)-3-hydroxybutanoyl-CoA ← crotonyl-CoA + H2O ,
4.2.1.-: benzyl-6-hydroxy-2-cyclohexene-on-oyl + H2O = 6-hydroxy-2-cyclohexen-one-carboxylate + benzyl alcohol + H+ ,
4.2.1.-: (3R)-3-hydroxy-stearoyl-CoA → trans-octadec-2-enoyl-CoA + H2O ,
4.2.3.12: 7,8-dihydroneopterin 3'-triphosphate → PPPi + 6-pyruvoyl tetrahydropterin + H+ ,
4.3.1.3: L-histidine → ammonium + urocanate ,
4.3.1.4: a 5-formiminotetrahydrofolate + 2 H+ → ammonium + a 5,10-methenyltetrahydrofolate ,
4.3.1.17: L-serine → pyruvate + ammonium ,
4.3.1.19: L-threonine → 2-oxobutanoate + ammonium ,
4.3.2.1: L-arginino-succinate ↔ L-arginine + fumarate ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.2.5: a C-terminal [protein]-hydroxyglycine = a peptidyl amide + glyoxylate ,
4.3.2.-: sphingosine 1-phosphate → 2-trans-hexadecenal + phosphoryl-ethanolamine ,
4.4.1.1: L-cystathionine + H2O → 2-oxobutanoate + L-cysteine + ammonium ,
4.4.1.5: (R)-S-lactoylglutathione ← methylglyoxal + glutathione ,
4.4.1.13: an L-cysteine-S-conjugate + H2O → pyruvate + a thiol + ammonium ,
4.4.1.16: L-selenocysteine + a reduced electron acceptor = L-alanine + selenide + an oxidized electron acceptor + 2 H+ ,
4.4.1.20: leukotriene-C4 ← leukotriene A4 + glutathione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.6.1.1: ATP = cyclic-AMP + diphosphate ,
4.6.1.2: GTP = cyclic-GMP + diphosphate ,
4.6.1.15: FAD = AMP + riboflavin cyclic-4',5'-phosphate ,
4.6.1.16: a polycistronic tRNA precursor → a tRNA intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus + a 3' half-tRNA molecule with a hydroxyl on its 5' end + a 5' half-tRNA molecule with a 2',3' cyclic phosphate on its 3' end ,
4.99.1.1: protoporphyrin IX + Fe2+ → ferroheme b + 2 H+ ,
5.1.1.18: L-serine = D-serine ,
5.1.2.3: a (3R)-3-hydroxyacyl-CoA → a (3S)-3-hydroxyacyl-CoA ,
5.1.3.1: D-ribulose 5-phosphate → D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.3: β-D-galactose → α-D-galactose ,
5.1.3.7: UDP-N-acetyl-α-D-glucosamine → UDP-N-acetyl-α-D-galactosamine ,
5.1.3.8: an N-acyl-D-glucosamine = an N-acyl-D-mannosamine ,
5.1.3.14: UDP-N-acetyl-α-D-glucosamine = UDP-N-acetyl-α-D-mannosamine ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.17: [heparan-sulfate]-β-D-glucuronate ↔ [heparan-sulfate]-α-L-iduronate ,
5.1.3.19: [chondroitin-sulfate]-β-D-glucuronate → [dermatan]-α-L-iduronate ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.1.99.1: (R)-methylmalonyl-CoA ← (S)-methylmalonyl-CoA ,
5.1.99.4: (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA ↔ (25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA ,
5.1.99.4: (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ↔ (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ,
5.1.99.4: a (2S)-2-methylacyl-CoA ↔ a (2R)-2-methylacyl-CoA ,
5.1.99.6: (R)-NADHX → (S)-NADHX ,
5.2.1.2: 4-maleyl-acetoacetate → 4-fumaryl-acetoacetate ,
5.2.1.8: peptidylproline (ω = 180) = peptidylproline (ω = 0) ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.6: D-ribose 5-phosphate ← D-ribulose 5-phosphate ,
5.3.1.8: α-D-mannose 6-phosphate ← β-D-fructofuranose 6-phosphate ,
5.3.1.9: D-glucopyranose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: α-D-glucose 6-phosphate = β-D-fructofuranose 6-phosphate ,
5.3.1.22: hydroxypyruvate = tartronate semialdehyde ,
5.3.1.23: S-methyl-5-thio-α-D-ribose 1-phosphate → 5-methylthioribulose 1-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.5: 5-(methylthio)-2,3-dioxopentyl 1-phosphate → 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl 1-phosphate + H+ ,
5.3.2.8: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate ↔ (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
5.3.3.1: a 3-oxo-δ5-steroid = a 3-oxo-Δ4-steroid ,
5.3.3.1: pregn-5-ene-3,20-dione → progesterone ,
5.3.3.1: campesterol = campest-4-en-3β-ol ,
5.3.3.1: cholest-5-en-3-one = cholest-4-en-3-one ,
5.3.3.1: 5-androstene-3,17-dione → androst-4-ene-3,17-dione ,
5.3.3.1: pregn-5-ene-3,20-dione-17-ol = 17-α-hydroxyprogesterone ,
5.3.3.1: 3-oxo-24-ethyl-cholest-5-ene = 3-oxo-24-ethyl-cholest-4-ene ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.5: lathosterol ← zymostenol ,
5.3.3.5: zymosterol → 5α-cholesta-7,24-dien-3β-ol ,
5.3.3.8: a trans-3-enoyl-CoA = a trans-2-enoyl-CoA ,
5.3.3.8: a trans2,cis-5-dienoyl-CoA = a trans3,cis-5-dienoyl-CoA ,
5.3.3.8: a cis-3-enoyl-CoA → a trans-2-enoyl-CoA ,
5.3.3.8: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA ,
5.3.3.12: L-dopachrome → 5,6-dihydroxyindole-2-carboxylate ,
5.3.3.-: a trans3,cis-5-dienoyl-CoA = a trans-2,trans-4-dienoyl-CoA ,
5.3.99.2: prostaglandin-H2 → prostaglandin D2 ,
5.3.99.3: prostaglandin-H2 → prostaglandin E2 ,
5.3.99.4: prostaglandin-H2 → prostaglandin I2 ,
5.3.99.5: prostaglandin-H2 → thromboxane A2 ,
5.4.1.-: α-lactose = allolactose ,
5.4.2.3: N-acetyl-α-D-glucosamine 1-phosphate ← N-acetyl-D-glucosamine 6-phosphate ,
5.4.2.4: 1,3-bisphospho-D-glycerate → 2,3-diphospho-D-glycerate + H+ ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.5: α-D-glucose 1-phosphate → D-glucopyranose 6-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate → D-ribose 5-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ← α-D-mannose 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.99.2: (R)-methylmalonyl-CoA → succinyl-CoA ,
5.4.99.7: (3S)-2,3-epoxy-2,3-dihydrosqualene = lanosterol ,
5.4.99.25: a tRNA uridine55 = a tRNA pseudouridine55 ,
5.4.99.26: a tRNA uridine65 = a tRNA pseudouridine65 ,
5.4.99.27: a tRNA uridine13 = a pseudouridine13 in tRNA ,
5.4.99.28: a tRNA uridine32 = a pseudouridine32 in tRNA ,
5.5.1.4: D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate ,
5.5.1.4: β-D-glucose 6-phosphate = 1D-myo-inositol 3-monophosphate ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.2: a carboxylate + ATP + coenzyme A → an acyl-CoA + AMP + diphosphate ,
6.2.1.3: decanoate + ATP + coenzyme A → decanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: linoleate + ATP + coenzyme A → linoleoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: palmitate + ATP + coenzyme A → palmitoyl-CoA + AMP + diphosphate ,
6.2.1.3: octanoate + ATP + coenzyme A → octanoyl-CoA + AMP + diphosphate ,
6.2.1.3: oleate + ATP + coenzyme A → oleoyl-CoA + AMP + diphosphate ,
6.2.1.3: ATP + α-linolenate + coenzyme A → α-linolenoyl-CoA + AMP + diphosphate ,
6.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: phytenate + ATP + coenzyme A → phytenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: pristanate + ATP + coenzyme A → pristanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a long-chain fatty acid + ATP + coenzyme A → a long-chain acyl-CoA + AMP + diphosphate ,
6.2.1.3: icosapentaenoate + ATP + coenzyme A → eicosapentaenoyl-CoA + AMP + diphosphate ,
6.2.1.3: (15Z)-tetracosenoate + ATP + coenzyme A → (Z)-15-tetracosenoyl-CoA + AMP + diphosphate ,
6.2.1.4: succinate[mitochondrial lumen] + GTP[mitochondrial lumen] + coenzyme A[mitochondrial lumen] ↔ succinyl-CoA[mitochondrial lumen] + GDP[mitochondrial lumen] + phosphate[mitochondrial lumen] ,
6.2.1.5: succinate[mitochondrial lumen] + ATP[mitochondrial lumen] + coenzyme A[mitochondrial lumen] ↔ succinyl-CoA[mitochondrial lumen] + ADP[mitochondrial lumen] + phosphate[mitochondrial lumen] ,
6.2.1.7: (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + ATP + coenzyme A → (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + AMP + diphosphate ,
6.2.1.7: ATP + cholate + coenzyme A → AMP + choloyl-CoA + diphosphate ,
6.2.1.12: 4-coumarate + ATP + coenzyme A → 4-coumaryl-CoA + AMP + diphosphate ,
6.2.1.15: arachidonate + ATP + coenzyme A → arachidonyl-CoA + AMP + diphosphate ,
6.2.1.16: acetoacetate + ATP + coenzyme A → acetoacetyl-CoA + AMP + diphosphate ,
6.2.1.24: phytanate + ATP + coenzyme A → phytanoyl-CoA + AMP + diphosphate ,
6.2.1.28: ATP + (25R)-3α,7α-dihydroxy-5-β-cholestanate + coenzyme A → AMP + (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + diphosphate ,
6.2.1.41: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + coenzyme A → 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate ,
6.2.1.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.-: 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoate + ATP + coenzyme A → OPC8-CoA + AMP + diphosphate ,
6.2.1.-: 3-oxocholest-4-en-26-oate + ATP + coenzyme A → 3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate ,
6.3.1.1: L-aspartate + ammonium + ATP → L-asparagine + AMP + diphosphate + H+ ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.14: a diphthine-[translation elongation factor 2] + ammonium + ATP → a diphthamide-[translation elongation factor 2] + AMP + diphosphate + H+ ,
6.3.2.2: L-cysteine + L-glutamate + ATP → γ-L-glutamyl-L-cysteine + ADP + phosphate + H+ ,
6.3.2.3: glycine + γ-L-glutamyl-L-cysteine + ATP → glutathione + ADP + phosphate + H+ ,
6.3.2.5: (R)-4'-phosphopantothenate + L-cysteine + CTP → R-4'-phosphopantothenoyl-L-cysteine + CMP + diphosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.11: 4-aminobutanoate + L-histidine + ATP → homocarnosine + ADP + phosphate + H+ ,
6.3.2.11: β-alanine + L-histidine + ATP → carnosine + ADP + phosphate + H+ ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: (R)-4'-phosphopantothenate + L-cysteine + ATP → R-4'-phosphopantothenoyl-L-cysteine + AMP + diphosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: an N5-formyl-tetrahydrofolate + ATP → a 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.3: a tetrahydrofolate + ATP + formate → 10-formyl-tetrahydropteroyl-[γ-Glu](n) + ADP + phosphate ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP ↔ L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.11: an apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + biotin + ATP → a holo [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + AMP + diphosphate ,
6.3.4.13: ATP + 5-phospho-β-D-ribosylamine + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.16: ammonium + CO2 + 2 ATP + H2O → carbamoyl-phosphate + 2 ADP + phosphate + 3 H+ ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → L-glutamate + AMP + NAD+ + diphosphate + H+ ,
6.3.5.2: XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+ ,
6.3.5.4: L-glutamine + L-aspartate + ATP + H2O → L-glutamate + L-asparagine + AMP + diphosphate + H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.4.1.1: hydrogen carbonate[mitochondrial lumen] + pyruvate[mitochondrial lumen] + ATP[mitochondrial lumen] → oxaloacetate[mitochondrial lumen] + ADP[mitochondrial lumen] + phosphate[mitochondrial lumen] + H+[mitochondrial lumen] ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.3: ATP + hydrogen carbonate + propanoyl-CoA → (S)-methylmalonyl-CoA + ADP + phosphate + H+ ,
6.4.1.4: hydrogen carbonate + 3-methylcrotonyl-CoA + ATP → ADP + 3-methylglutaconyl-CoA + phosphate + H+ ,
6.5.1.6: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
6.5.1.7: (deoxynucleotides)(m) + ATP + (deoxynucleotides)(n) → (deoxynucleotides)(n+m) + AMP + diphosphate ,
6.-.-.-: a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + H+ → a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
L-arginine[extracellular space] → L-arginine[cytosol] ,
L-asparagine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-asparagine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
2 hydrogen carbonate[extracellular space] + Na+[extracellular space] + chloride[cytosol] → 2 hydrogen carbonate[cytosol] + Na+[cytosol] + chloride[extracellular space] ,
Na+[extracellular space] + phosphate[extracellular space] → Na+[cytosol] + phosphate[cytosol] ,
L-phenylalanine[extracellular space] → L-phenylalanine[cytosol] ,
glycine[cytosol] → glycine[vesicle lumen] ,
Zn2+[extracellular space] → Zn2+[cytosol] ,
L-ornithine[cytosol] → L-ornithine[mitochondrial lumen] ,
an O-acyl-L-carnitine[mitochondrial lumen] + L-carnitine[mitochondrial intermembrane space] → an O-acyl-L-carnitine[mitochondrial intermembrane space] + L-carnitine[mitochondrial lumen] ,
L-isoleucine[extracellular space] + Na+[extracellular space] → L-isoleucine[cytosol] + Na+[cytosol] ,
acetoacetate[extracellular space] + H+[extracellular space] → acetoacetate[cytosol] + H+[cytosol] ,
chloride[extracellular space] + hydrogen carbonate[cytosol] → chloride[cytosol] + hydrogen carbonate[cytosol] ,
L-glutamine[extracellular space] + L-arginine[cytosol] → L-glutamine[cytosol] + L-arginine[extracellular space] ,
a monocarboxylate[extracellular space] + H+[extracellular space] → a monocarboxylate[cytosol] + H+[cytosol] ,
L-serine[extracellular space] + Na+[extracellular space] → L-serine[cytosol] + Na+[cytosol] ,
2 hydrogen carbonate[extracellular space] + Na+[extracellular space] → 2 hydrogen carbonate[cytosol] + Na+[cytosol] ,
Ca2+[extracellular space] + Li+[cytosol] → Ca2+[cytosol] + Li+[extracellular space] ,
Ca2+[mitochondrial intermembrane space] → Ca2+[mitochondrial lumen] ,
glycine[extracellular space] + Na+[extracellular space] → glycine[cytosol] + Na+[cytosol] ,
L-histidine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-histidine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
Ca2+[cytosol] + 4 Na+[extracellular space] + K+[cytosol] → Ca2+[extracellular space] + 4 Na+[cytosol] + K+[extracellular space] ,
acetyl-CoA[cytosol] → acetyl-CoA[endoplasmic reticulum lumen] ,
L-tryptophan[extracellular space] → L-tryptophan[cytosol] ,
L-alanine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-alanine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
β-D-glucose[extracellular space] → β-D-glucose[cytosol] ,
hydrogen carbonate[extracellular space] + Na+[extracellular space] + chloride[cytosol] → hydrogen carbonate[cytosol] + Na+[cytosol] + chloride[extracellular space] ,
L-tyrosine[extracellular space] → L-tyrosine[cytosol] ,
Na+[extracellular space] → Na+[cytosol] ,
(R)-noradrenaline[extracellular space] + Na+[extracellular space] → (R)-noradrenaline[cytosol] + Na+[cytosol] ,
3'-phosphoadenylyl-sulfate[cytosol] → 3'-phosphoadenylyl-sulfate[golgi lumen] ,
(R)-3-hydroxybutanoate[extracellular space] + H+[extracellular space] → (R)-3-hydroxybutanoate[cytosol] + H+[cytosol] ,
4-aminobutanoate[cytosol] → 4-aminobutanoate[vesicle lumen] ,
4-aminobutanoate[extracellular space] + Na+[extracellular space] + chloride[extracellular space] → 4-aminobutanoate[cytosol] + Na+[cytosol] + chloride[cytosol] ,
D-glucose[extracellular space] + 2 Na+[extracellular space] → D-glucose[cytosol] + 2 Na+[cytosol] ,
L-valine[extracellular space] + Na+[extracellular space] → L-valine[cytosol] + Na+[cytosol] ,
lactate[extracellular space] + H+[extracellular space] → lactate[cytosol] + H+[cytosol] ,
L-cystine[extracellular space] → L-cystine[cytosol] ,
an mRNA + H2O = an RNase product with a 3' phosphate + an RNase product with a 5' OH ,
L-glutamate[cytosol] → L-glutamate[vesicle lumen] ,
L-alanine[extracellular space] + Na+[extracellular space] → L-alanine[cytosol] + Na+[cytosol] ,
L-glutamate[extracellular space] + Na+[extracellular space] → L-glutamate[cytosol] + Na+[cytosol] ,
GDP-L-fucose[cytosol] → GDP-L-fucose[golgi lumen] ,
(S)-reticuline → 1,2-dehydroreticulinium + 2 H+ ,
L-serine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-serine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
Na+[extracellular space] + H+[cytosol] → Na+[cytosol] + H+[extracellular space] ,
myo-inositol[extracellular space] + H+[extracellular space]myo-inositol[cytosol] + H+[cytosol] ,
L-leucine[extracellular space] → L-leucine[cytosol] ,
glycine[extracellular space] + Na+[extracellular space] + H+[cytosol] → glycine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
borate[extracellular space] + 2 Na+[extracellular space] → borate[cytosol] + 2 Na+[cytosol] ,
chloride[extracellular space] + Na+[extracellular space] + glycine betaine[extracellular space] → chloride[cytosol] + Na+[cytosol] + glycine betaine[cytosol] ,
acetate[extracellular space] + H+[extracellular space] → acetate[cytosol] + H+[cytosol] ,
a neutral amino acid[extracellular space] + Na+[extracellular space] → a neutral amino acid[cytosol] + Na+[cytosol] ,
chloride[cytosol] → chloride[endosome lumen] ,
Ca2+[cytosol] + Na+[extracellular space] ↔ Ca2+[extracellular space] + Na+[cytosol] ,
L-leucine[extracellular space] + Na+[extracellular space] → L-leucine[cytosol] + Na+[cytosol] ,
pyruvate[extracellular space] + H+[extracellular space] → pyruvate[cytosol] + H+[cytosol] ,
K+[extracellular space] ↔ K+[cytosol] ,
chloride[nuclear lumen] → chloride[cytosol] ,
L-ascorbate[extracellular space] + 2 Na+[extracellular space] → L-ascorbate[cytosol] + 2 Na+[cytosol] ,
L-methionine[extracellular space] + Na+[extracellular space] → L-methionine[cytosol] + Na+[cytosol] ,
acetylcholine[cytosol] + H+[vesicle lumen] → acetylcholine[vesicle lumen] + H+[cytosol] ,
a neutral amino acid[extracellular space] + 2 Na+[cytosol] + chloride[cytosol] → a neutral amino acid[cytosol] + 2 Na+[cytosol] + chloride[cytosol] ,
L-glutamine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-glutamine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
choline[extracellular space] + Na+[extracellular space] + chloride[extracellular space] → choline[cytosol] + Na+[cytosol] + chloride[cytosol] ,
myo-inositol[extracellular space] + Na+[extracellular space]myo-inositol[cytosol] + Na+[cytosol] ,
L-glutamate[in] + L-cystine[out] → L-cystine[in] + L-glutamate[out] ,
sn-glycerol 3-phosphate[mitochondrial intermembrane space]sn-glycerol 3-phosphate[cytosol] ,
dihydroxyacetone phosphate[mitochondrial intermembrane space] ↔ dihydroxyacetone phosphate[cytosol] ,
citrate[mitochondrial intermembrane space] ↔ citrate[cytosol] ,
citrate[mitochondrial lumen] + (S)-malate[mitochondrial intermembrane space] → citrate[mitochondrial intermembrane space] + (S)-malate[mitochondrial lumen] ,
(S)-1-pyrroline-5-carboxylate[in] ↔ (S)-1-pyrroline-5-carboxylate[out] ,
ammonia[in] ↔ ammonia[out] ,
L-glutamate[mitochondrial lumen] + H+[mitochondrial lumen] ↔ L-glutamate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] ,
oxaloacetate[mitochondrial intermembrane space] ↔ oxaloacetate[cytosol] ,
2-oxoglutarate[mitochondrial intermembrane space] ↔ 2-oxoglutarate[cytosol] ,
(S)-malate[mitochondrial intermembrane space] ↔ (S)-malate[cytosol] ,
L-aspartate[mitochondrial intermembrane space] ↔ L-aspartate[cytosol] ,
L-glutamate[mitochondrial intermembrane space] ↔ L-glutamate[cytosol] ,
L-glutamate[out] + L-aspartate[in] + H+[out] → L-glutamate[in] + L-aspartate[out] + H+[in] ,
(S)-malate[mitochondrial lumen] + 2-oxoglutarate[mitochondrial intermembrane space] ↔ (S)-malate[mitochondrial intermembrane space] + 2-oxoglutarate[mitochondrial lumen] ,
oxygen[in] ↔ oxygen[out] ,
phosphate[mitochondrial intermembrane space] ↔ phosphate[cytosol] ,
H+[mitochondrial intermembrane space] ↔ H+[cytosol] ,
H2O[mitochondrial lumen] ↔ H2O[mitochondrial intermembrane space] ,
phosphate[mitochondrial lumen] + H+[mitochondrial lumen] ← phosphate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] ,
ATP[mitochondrial intermembrane space] ↔ ATP[cytosol] ,
ADP[mitochondrial intermembrane space] + ATP[mitochondrial lumen] → ADP[mitochondrial lumen] + ATP[mitochondrial intermembrane space] ,
L-carnitine[mitochondrial intermembrane space] ↔ L-carnitine[cytosol] ,
an O-acyl-L-carnitine[mitochondrial intermembrane space] ↔ an O-acyl-L-carnitine[cytosol] ,
8 H+[in] → 8 H+[out] ,
pyruvate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] → pyruvate[mitochondrial lumen] + H+[mitochondrial lumen] ,
pyruvate[cytosol] ↔ pyruvate[mitochondrial intermembrane space] ,
D-serine[extracellular space] → D-serine[cytosol] ,
Na+[extracellular space] + L-cysteine[extracellular space] → Na+[cytosol] + L-cysteine[cytosol] ,
Na+[extracellular space] + L-glutamine[extracellular space] → L-glutamine[cytosol] + Na+[cytosol] ,
glycine[extracellular space] + H+[extracellular space] → glycine[cytosol] + H+[cytosol] ,
L-glutamate[extracellular space] + Na+[extracellular space] → L-glutamate[cytosol] + Na+[cytosol] ,
K+[out] → K+[in] ,
K+[out] → K+[in] ,
K+[out] → K+[in] ,
H2O[mitochondrial intermembrane space] ↔ H2O[cytosol] ,
ADP[mitochondrial intermembrane space] ↔ ADP[cytosol] ,
Na+[extracellular space] + L-threonine[extracellular space] → Na+[cytosol] + L-threonine[cytosol] ,
L-proline[extracellular space] + H+[extracellular space] → L-proline[cytosol] + H+[cytosol] ,
L-alanine[extracellular space] + H+[extracellular space] → L-alanine[cytosol] + H+[cytosol] ,
L-aspartate[extracellular space] + Na+[extracellular space] → L-aspartate[cytosol] + Na+[cytosol] ,
4 H+[in] → 4 H+[out] ,
an L-cysteine-S-conjugate = a thiol + 2-aminoprop-2-enoate + H+ ,
2 H+[in] → 2 H+[out] ,
a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-carboxy-3-(methylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
13'-hydroxy-α-tocopherol → 5'-α-carboxylmethylbutylhydroxychroman ,
aldehydo-D-ribose ↔ D-ribopyranose ,
2 L-arginine + 2 NADPH + 2 H+ + 2 oxygen = 2 Nω-hydroxy-L-arginine + 2 NADP+ + 2 H2O ,
tyramine → dopamine ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
2-oxo-4-methylthiobutanoate + hydroxyl radical → ethylene + methanethiol + 2 CO2 ,
7-O-acetylsalutaridinol → thebaine + acetate + H+ ,
3,3',5,5'-tetraiodothyronamine + a reduced electron acceptor → 3,3',5-triiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
arachidonate + a reduced electron acceptor + oxygen → 15S-hydroxypentaenoate + an oxidized electron acceptor + H2O ,
L-tyrosine + 0.5 oxygen → L-dopa ,
simvastatin lactone + H2O → simvastatin acid + H+ ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
4,4-dimethylzymosterol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
3-iodo-L-tyrosine + iodide + NADP+ ← 3,5-diiodo-L-tyrosine + NADPH + H+ ,
formaldehyde + a tetrahydrofolate → a 5,10-methylene-tetrahydrofolate + H2O ,
4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + 2 H2O ,
5-methoxyindoleacetaldehyde + a reduced electron acceptor → 5-methoxytryptophol + an oxidized electron acceptor ,
4-oxo-4-(3-pyridyl)-N-methylbutanamide → 4-oxo-4-(3-pyridyl)-butanoate ,
L-dehydro-ascorbate + NADPH → L-ascorbate + NADP+ ,
24,25-dihydrolanosterol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADP+ + H2O ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
S-adenosyl-L-methionine + an N terminal N-methyl-PPK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-PPK-[protein] + H+ ,
(25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + an oxidized electron acceptor → (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + a reduced electron acceptor ,
S-adenosyl-L-methionine + an N terminal N-methyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-(A/S)PK-[protein] + H+ ,
NADH + H2O → (S)-NADHX ,
5β-cholestane-3α,7α,12α-triol + NADPH + oxygen + H+ → (25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADP+ + H2O ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate ,
a [protein] N6,N6-dimethyl-L-lysine + 2-oxoglutarate + oxygen = a [protein] N6-methyl-L-lysine + succinate + formaldehyde + CO2 ,
prephytoene diphosphate = 15-cis-phytoene + diphosphate ,
(9Z,15Z)-12,13-epoxy-octadeca-9,15-dienoate + H2O = (9Z,15Z)-12,13-dihydroxyoctadeca-9,15-dienoate ,
17-hydro(p)docosahexaenoate + an oxidized electron acceptor + H2O → 4S-hydroperoxy,17R-H-docosahexaenoate + a reduced electron acceptor ,
arachidonate + NADPH + oxygen + H+ → (15R)-hydroxyeicosapentaenoate + NADP+ + H2O ,
4-oxoglutaramate + H2O → 2-oxoglutarate + ammonium ,
5,6-dihydroxyindole-2-carboxylate + 2 H+ + oxygen → indole-5,6-quinone-2-carboxylate + 2 H2O ,
a 2(R)-hydroperoxy fatty acid + H+ → a fatty aldehyde + CO2 + H2O ,
14-hydroxylanosterol + NADPH + H+ + oxygen → 14-oxolanosterol + NADP+ + 2 H2O ,
melatonin + H2O → 5-methoxytryptamine + acetate + H+ ,
4,4-dimethyl-5α-cholest-7-en-3β-ol + NAD(P)H + oxygen + H+ = 4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + NAD(P)+ + H2O ,
α-D-ribose 5-phosphate → β-D-ribose 5-phosphate ,
nornicotine + H2O → norcotinine + 5 H+ ,
keto-L-sorbose ↔ L-sorbopyranose ,
3-methoxy-4-hydroxyphenylpyruvate + NADH + H+ ↔ 3-methoxy-4-hydroxyphenyllactate + NAD+ ,
cyclic ADP-ribose + H2O = ADP-D-ribose + H+ ,
15,15'-dihydroxy-β-carotene + an oxidized electron acceptor = 2 all-trans-retinal + a reduced electron acceptor ,
(25R)-5β-cholestane-3α,7α,26-triol + NADPH + H+ + oxygen → (25R)-3α,7α-dihydroxy-5β-cholestan-26-al + NADP+ + 2 H2O ,
cyclic-2,3-O-oxalyl-L-threonate → cyclic- 3,4-O-oxalyl-L-threonate ,
2-aminoprop-2-enoate + H+ + H2O → pyruvate + ammonium ,
glutathione + intracellular S0 → S-sulfanylglutathione ,
a vernolate + H2O = (9Z)-12,13-dihydroxyoctadeca-9-enoate ,
5,6-epoxy,18R-hydroxy-eicosapentaenoate + 2 H+ = resolvin E2 ,
3,3',5'-triiodothyronamine + a reduced electron acceptor → 3',5'-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
3,3'-diiodothyronine + a reduced electron acceptor → 3'-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
4-imidazolone-5-propionate + H2O → formyl-L-isoglutamine ,
19-hydroxytestosterone + a reduced flavoprotein + oxygen → 19-oxo-testosterone + an oxidized flavoprotein + 2 H2O ,
2-oxoadipate + coenzyme A + NAD+ → CO2 + glutaryl-CoA + NADH ,
squalene + NAD(P)+ + diphosphate = presqualene diphosphate + NAD(P)H + H+ ,
(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADPH + oxygen → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + NADP+ + H2O ,
bupropion + 2 H+ = erythrohydrobupropion ,
XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+ ,
4,4-dimethyl-5α-cholesta-8-en-3-β-ol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+ ↔ (E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein ,
D-myo-inositol (1,3,4,6)-tetrakisphosphate = D-myo-inositol (1,3,4,5)-tetrakisphosphate ,
D-arabinofuranose ↔ D-arabinopyranose ,
CTP + hydroxyl radical → 5-hydroxy-CTP + H+ ,
aldehydo-D-mannose → β-D-mannose ,
3,5,3'-triiodo-L-thyronine → 3,3',5-triiodothyroacetate ,
an [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + NADH + H+ = an [eIF5A-precursor]-deoxyhypusine + NAD+ ,
2 L-dehydro-ascorbate + oxygen → 2 cyclic-2,3-O-oxalyl-L-threonate + 2 H+ ,
3'-iodothyronamine + a reduced electron acceptor → thyronamine + iodide + an oxidized electron acceptor + H+ ,
5,6-epoxy,18R-hydroxy-eicosapentaenoate + H2O = resolvin E1 ,
ammonia + H+ ↔ ammonium ,
19-hydroxyandrostenedione + a reduced flavoprotein + oxygen → 19-oxoandrostenedione + an oxidized flavoprotein + 2 H2O ,
2-oxoadipate + ammonium + NAD+ ← 2-aminomuconate + NADH + H2O + 2 H+ ,
4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
a 2-[(3S)-3-carboxy-3-(methylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
a 2-monoglyceride → a 1-monoglyceride ,
4-(3-pyridyl)-butanoate → 3-pyridylacetate ,
an Fe(II)-siderophore + H+ → a siderophore + Fe2+ ,
4-coumaryl-CoA + coenzyme A + NAD+ + H2O → 4-hydroxybenzoyl-CoA + acetyl-CoA + NADH + H+ ,
(3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H2O + H+ ↔ L-4-hydroxyglutamate semialdehyde ,
spermidine + NAD+ = dehydrospermidine + NADH + H+ ,
3-hydroxy-N6,N6,N6-trimethyl-L-lysine → 4-trimethylammoniobutanal + glycine ,
pre-vitamin D3 + heat → vitamin D3 ,
L-dehydro-ascorbate + H2O → dehydroascorbate (bicyclic form) ,
3,3'-diiodothyronamine + a reduced electron acceptor → 3-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
icosapentaenoate + a reduced electron acceptor + oxygen → 18R-hydroxy-eicosapentaenoate + an oxidized electron acceptor + H2O ,
ribose-1-arsenate + dihydrolipoate + H+ → D-ribofuranose + arsenite + (R)-lipoate ,
3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)H + oxygen = 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + NAD(P)+ + H2O ,
5'-α-carboxylmethylbutylhydroxychroman → α-carboxyethylhydroxychroman ,
adenine + hydroxyl radical → isoguanine + H+ ,
4-oxo-4-(3-pyridyl)-butanoate + 2 H+ → 4-hydroxy-4-(3-pyridyl)-butanoate ,
sphingosine 1-phosphate + H2O → sphingosine + phosphate ,
4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate → xanthurenate + H+ + H2O ,
2 Nω-hydroxy-L-arginine + NADPH + 2 oxygen = 2 L-citrulline + 2 nitric oxide + NADP+ + 2 H2O + H+ ,
3,4-dihydroxyphenylpyruvate + H+ → 3,4-dihydroxyphenylacetaldehyde + CO2 ,
(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + NAD+ → 3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + NADH + H+ ,
hydrogen peroxide + Fe2+ → hydroxyl radical + Fe3+ + OH- ,
2 geranylgeranyl diphosphate = prephytoene diphosphate + diphosphate ,
docosahexaenoate + 2 a reduced electron acceptor + 2 oxygen → 17S-hydro(p)docosahexaenoate + 2 an oxidized electron acceptor + 2 H2O ,
3,3',5,5'-tetraiodothyronamine + a reduced electron acceptor → 3,3',5'-triiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
15S-hydroxypentaenoate + oxygen → lipoxin A4 ,
n melanochrome → eumelanin ,
4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + 2 H2O ,
a D-glucosyl-N-acylsphinganine + NADPH + oxygen + H+ = a D-glucosyl-N-acylsphingosine + NADP+ + 2 H2O ,
4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → 4α-carboxy-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
melatonin + hydrogen peroxide → N1-acetyl-N2-formyl-5-methoxykynuramine + 2 H+ ,
cotinine → cotinine N-oxide ,
L-ascorbate + an oxidized electron acceptor + 2 H+ → monodehydroascorbate radical + a reduced electron acceptor ,
4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADP+ + 2 H2O ,
D-altropyranose ↔ aldehydo-D-altrose ,
sphingosine + ATP → sphingosine 1-phosphate + ADP + H+ ,
an [L-cysteine desulfurase] L-cysteine persulfide + a ThiI sulfur-carrier protein = an [L-cysteine desulfurase]-L-cysteine + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
di-trans, poly-cis-polyprenyl diphosphate (C80) + H2O → di-trans, poly-cis-polyprenol (C80) + diphosphate ,
[thyroglobulin]-triiodothyronine + H2O → 3,5,3'-triiodo-L-thyronine + [unspecified degradation products] ,
NADH + H2O → (R)-NADHX ,
L-rhamnopyranose ↔ L-rhamnofuranose ,
2 L-cysteine → lanthionine + hydrogen sulfide ,
3,3',5'-triiodo-L-thyronine + a reduced electron acceptor → 3',5'-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
(15R)-hydroxyeicosapentaenoate + oxygen → 15 epi-lipoxin A4 ,
indole-5,6-quinone + indole-5,6-quinone-2-carboxylate → melanochrome ,
14-oxolanosterol + NADPH + oxygen → 14-demethyllanosterol + formate + NADP+ + H2O ,
3-oxo-3-phenylpropanoyl-CoA + coenzyme A = benzoyl-CoA + acetyl-CoA ,
ethanol + NADPH + oxygen + H+ → acetaldehyde + NADP+ + 2 H2O ,
β-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
2-aminoprop-2-enoate → 2-iminopropanoate ,
norcotinine → 4-oxo-4-(3-pyridyl)-butanamide ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
3-methoxy-4-hydroxyphenylpyruvate → homovanillate ,
dATP + hydroxyl radical → 2-hydroxy-dATP + H+ ,
5-hydroxyindole acetaldehyde + L-cysteine ↔ 5-hydroxyindole thiazolidine carboxylate + H2O ,
NADP+ = 2'-phospho-cyclic ADP-ribose + nicotinamide ,
a 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one → a 3-isopropenyl-6-oxoheptanoate + H+ ,
S-adenosyl-L-methionine + an N terminal N,N-dimethyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein] + H+ ,
(25R)-3α,7α-dihydroxy-5β-cholestan-26-al + NADPH + oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + NADP+ + H2O ,
(5S)-HPETE → leukotriene A4 + H2O ,
2-keto-6-aminocaproate + hydrogen peroxide → 5-aminopentanoate + CO2 + H2O ,
(9Z,12Z)-15,16-epoxyoctadeca-9,12-dienoate + H2O = (9Z,12Z)-15,16-dihydroxyoctadeca-9,12-dienoate ,
ammeline + H2O = ammelide + ammonium ,
3',5'-diiodothyronamine + a reduced electron acceptor → 3'-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
3'-monoiodothyronine + a reduced electron acceptor → L-thyronine + iodide + an oxidized electron acceptor + H+ ,
formyl-L-isoglutamine + H2O → L-isoglutamine + formate ,
1-(3-aminopropyl)-4-aminobutanal → 1-(3-aminopropyl)-pyrrolinium + H2O ,
19-oxo-testosterone + a reduced flavoprotein + oxygen → 17β-estradiol + formate + an oxidized flavoprotein + H2O + H+ ,
L-dopachrome + H+ → 5,6-dihydroxyindole + CO2 ,
bupropion → 3-chlorobenzoate ,
4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + 2 H2O ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
aldehydo-L-arabinose ↔ L-arabinopyranose ,
aldehydo-D-xylose ↔ a D-xylopyranose ,
(R)-methylmalonate-semialdehyde ↔ (S)-methylmalonate-semialdehyde ,
sulfite + 2 Fe3+ + H2O = sulfate + 2 Fe2+ + 2 H+ ,
L-thyroxine = 3-iodothyronamine ,
all-trans-β-carotene + a reduced electron acceptor + oxygen = β-carotene 15,15' epoxide + an oxidized electron acceptor + H2O ,
2,3-dioxo-L-gulonate → 2-carboxy-L-xylonolactone ,
L-erythro-5,6,7,8-tetrahydrobiopterin + NADP+ = 6-lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ ,
2-oxoglutarate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + NAD+[mitochondrial lumen] → succinyl-CoA[mitochondrial lumen] + CO2[mitochondrial lumen] + NADH[mitochondrial lumen] ,
Δ1-piperideine-2-carboxylate + H+ + H2O ← 2-keto-6-aminocaproate ,
L-lysine + 2-oxoglutarate → 2-keto-6-aminocaproate + L-glutamate ,
3,3',5-triiodothyronamine + a reduced electron acceptor → 3,5-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
docosahexaenoate + 2 a reduced electron acceptor + 2 oxygen → 17-hydro(p)docosahexaenoate + 2 an oxidized electron acceptor + 2 H2O ,
3,3'-diiodothyronine + a reduced electron acceptor → 3-monoiodothyronine + iodide + an oxidized electron acceptor + H+ ,
19-oxoandrostenedione + a reduced flavoprotein + oxygen → estrone + formate + an oxidized flavoprotein + H2O + H+ ,
2 monodehydroascorbate radical → L-ascorbate + L-dehydro-ascorbate + H+ ,
L-lyxopyranose → aldehydo-L-lyxose ,
D-galactopyranuronate ↔ aldehydo-D-galacturonate ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
dehydrospermidine + a [deoxyhypusine synthase]-L-lysine = a [deoxyhypusine synthase]-N-(4-aminobutylidene)-lysine + propane-1,3-diamine ,
dehydroascorbate (bicyclic form) + hydrogen peroxide → L-threonate + oxalate + 3 H+ ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
3,3'-diiodothyronamine + a reduced electron acceptor → 3'-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
18R-hydroxy-eicosapentaenoate + oxygen → 5S hydro(peroxy),18R-hydroxy-eicosapentaenoate ,
intracellular S0n + a thiol → intracellular S0n-1 + a perthiol ,
citrate[mitochondrial lumen]cis-aconitate[mitochondrial lumen] + H2O[mitochondrial lumen] ,
4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + NAD(P)H + H+ + oxygen = 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)+ + 2 H2O ,
4α-methyl-zymosterol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
pyruvate + hydroxylamine → pyruvic oxime + H2O ,
4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
2'-deoxyadenosine + hydroxyl radical → 2-hydroxydeoxyadenosine + H+ ,
4-hydroxy-4-(3-pyridyl)-butanoate → 4-(3-pyridyl)-3-butenoate ,
5-phospho-α-D-ribose 1-diphosphate + H2O = α-D-ribose 1,5-bisphosphate + phosphate + H+ ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
2 L-homocysteine → hydrogen sulfide + L-homolanthionine ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
2-aminomuconate 6-semialdehyde → picolinate + H2O ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
dopamine + 3,4-dihydroxyphenylacetaldehyde → S-norlaudanosoline + H2O ,
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NAD(P)H + H+ → 2-dehydro-3-deoxy-D-gluconate + NAD(P)+ ,
2 Fe2+ + 2 oxygen → 2 superoxide + 2 Fe3+ ,
17S-hydro(p)docosahexaenoate + a reduced electron acceptor + oxygen → 7S-hydroperoxy,17S-H-docosahexaenoate + an oxidized electron acceptor + H2O ,
3,3',5-triiodothyronamine + a reduced electron acceptor → 3,3'-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
cacodylate + 3 H+ → dimethylarsinous acid + H2O ,
4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
leucodopachrome + dopaquinone → L-dopachrome + L-dopa ,
N1-acetyl-N2-formyl-5-methoxykynuramine + H2O → N-acetyl-5-methoxykynurenamine + formate + H+ ,
cotinine → cotinine methonium ion ,
4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADPH + oxygen → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate + NADP+ + H2O ,
aldehydo-D-ribose ↔ D-ribofuranose ,
sphinganine + a long-chain acyl-CoA → a dihydroceramide + coenzyme A + H+ ,
4-(2-aminophenyl)-2,4-dioxobutanoate → kynurenate + H2O + H+ ,
di-trans, poly-cis-polyprenol (C80) + NADPH + H+ → a dolichol + NADP+ ,
[thyroglobulin]-L-thyroxine + H2O → L-thyroxine + [unspecified degradation products] ,
(24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA + NAD+ → 3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + NADH + H+ ,
2-amino-3-oxobutanoate + 2 H+ → aminoacetone + CO2 ,
a CDP-diacylglycerol + an L-1-phosphatidyl-glycerol → a cardiolipin + CMP + H+ ,
2-oxobutanoate + coenzyme A + NAD+ → propanoyl-CoA + CO2 + NADH ,
(15R)-hydroxyeicosapentaenoate + oxygen → 15 epi-lipoxin B4 ,
(R)-lactaldehyde + NAD+ + H2O → (R)-lactate + NADH + 2 H+ ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
L-tyrosine + iodide + NADP+ ← 3-iodo-L-tyrosine + NADPH ,
4α-methyl-cholesta-8-enol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
5-methoxyindoleacetaldehyde + an oxidized electron acceptor + H2O → 5-methoxyindole acetate + a reduced electron acceptor ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
5'-hydroxycotinine → 4-oxo-4-(3-pyridyl)-N-methylbutanamide ,
L-serine → 2-aminoprop-2-enoate + H+ + H2O ,
4-oxo-4-(3-pyridyl)-butanamide → 4-oxo-4-(3-pyridyl)-butanoate ,
aldehydo-L-fucose ↔ L-fucopyranose ,
a dihydroceramide + NAD(P)H + oxygen + H+ → an N-acylsphingosine + NAD(P)+ + 2 H2O ,
ATP + UTP + ammonium → ADP + CTP + phosphate + 2 H+ ,
2'-phospho-cyclic ADP-ribose + nicotinate = nicotinate-adenine dinucleotide phosphate ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
stearidonoyl-CoA + malonyl-CoA + 2 NADPH + 3 H+ → eicosatetraenoyl-CoA + CO2 + coenzyme A + 2 NADP+ + H2O ,
S-adenosyl-L-methionine + an N-terminal-PPK-[protein] → S-adenosyl-L-homocysteine + an N terminal N-methyl-PPK-[protein] + H+ ,
S-adenosyl-L-methionine + an N-terminal-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N-methyl-(A/S)PK-[protein] + H+ ,
(25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADPH + oxygen + H+ → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADP+ + 2 H2O ,
sulfite + H+ ↔ bisulfite ,
arachidonate + oxygen → (5S)-HPETE ,
(12Z,15Z)-9,10-epoxyoctadeca-12,15-dienoate + H2O = (12Z,15Z)-9,10-dihydroxyoctadeca-12,15-dienoate ,
3,5,3'-triiodo-L-thyronine + a reduced electron acceptor → 3,5-diiodothyronine + iodide + an oxidized electron acceptor + H+ ,
4-imidazolone-5-propionate + oxygen + H2O + 2 H+ → 4-oxoglutaramate + ammonium + formate ,
1-(3-aminopropyl)-pyrrolinium → 1,5-diazabicyclononane + H+ ,
aminocarboxymuconate semialdehyde → quinolinate + H2O ,
5,6-dihydroxyindole + 2 H+ + oxygen → indole-5,6-quinone + 2 H2O ,
lanosterol + NADPH + H+ + oxygen → 14-hydroxylanosterol + NADP+ + H2O ,
3-chlorobenzoate + glycine → m-chlorohippurate + H2O ,
L-threonine = (2Z)-2-aminobut-2-enoate + H2O + H+ ,
(S)-nicotine + H2O → nornicotine + formaldehyde + 2 H+ ,
L-arabinofuranose ↔ L-arabinopyranose ,
keto-D-fructose → β-D-fructofuranose ,
3-O-methyldopa + 2-oxoglutarate + H+ ↔ 3-methoxy-4-hydroxyphenylpyruvate + L-glutamate ,
NAD+ = cyclic ADP-ribose + nicotinamide ,
3,5,3'-triiodo-L-thyronine → thyronamine ,
β-carotene 15,15' epoxide + H2O = 15,15'-dihydroxy-β-carotene ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
5β-cholestane-3α,7α-diol + NADPH + H+ + oxygen → (25R)-5β-cholestane-3α,7α,26-triol + NADP+ + H2O ,
2-carboxy-L-xylonolactone + H2O → 2-carboxy-L-threo-pentonate + H+ ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
prephytoene diphosphate = all-trans-phytoene + diphosphate ,
(S)-2-amino-6-oxohexanoate ↔ (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + H2O + H+ ,
3,5-diiodothyronamine + a reduced electron acceptor → 3-iodothyronamine + iodide + an oxidized electron acceptor + H+ ,
17-hydro(p)docosahexaenoate + an oxidized electron acceptor + H2O → 7S-hydroperoxy,17R-H-docosahexaenoate + a reduced electron acceptor ,
3-monoiodothyronine + a reduced electron acceptor → L-thyronine + iodide + an oxidized electron acceptor + H+ ,
testosterone + a reduced flavoprotein + oxygen → 19-hydroxytestosterone + an oxidized flavoprotein + H2O ,
bupropion + 2 H+ = threohydrobupropion ,
2'-hydroxynicotine → pseudooxynicotine ,
α-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
D-arabinopyranose → aldehydo-D-arabinose ,
aldehydo-D-mannose → D-mannopyranose ,
(S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD(P)+ + 2 H2O = L-2-aminoadipate + NAD(P)H + H+ ,
L-cystathionine → (2Z)-2-aminobut-2-enoate + L-cysteine + H+ ,
(1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate → (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
L-thyroxine → tetraiodothyroacetate ,
a [deoxyhypusine synthase]-N-(4-aminobutylidene)-lysine + an [eIF5A-precursor]-lysine = an [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + a [deoxyhypusine synthase]-L-lysine + H+ ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
(S)-propane-1,2-diol + NAD+ ← acetol + NADH + H+ ,
L-cysteine + L-homocysteine → L-cystathionine + hydrogen sulfide ,
3-iodothyronamine + a reduced electron acceptor → thyronamine + iodide + an oxidized electron acceptor + H+ ,
5S hydro(peroxy),18R-hydroxy-eicosapentaenoate → resolvin E1 ,
cis-aconitate + H2O → D-threo-isocitrate ,
androst-4-ene-3,17-dione + a reduced flavoprotein + oxygen → 19-hydroxyandrostenedione + an oxidized flavoprotein + H2O ,
4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + 2 H2O ,
a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a diphthine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
2 L-ascorbate + hydrogen peroxide + 2 H+ → 2 monodehydroascorbate radical + 2 H2O ,
4-(3-pyridyl)-3-butenoate + 2 H+ → 4-(3-pyridyl)-butanoate ,
3-(4-hydroxyphenyl)lactate → 4-coumarate + H2O ,
D-glucopyranuronate ↔ aldehydo-D-glucuronate ,
aldehydo-D-glucose → D-glucopyranose ,
S-norlaudanosoline + 3 S-adenosyl-L-methionine → (S)-reticuline + 3 S-adenosyl-L-homocysteine + 3 H+ ,
7-dehydrocholesterol + UV light → pre-vitamin D3 ,
dehydroascorbate (bicyclic form) → 2,3-dioxo-L-gulonate + H+ ,
(S)-1-pyrroline-5-carboxylate[mitochondrial lumen] + NAD+[mitochondrial lumen] + 2 H2O[mitochondrial lumen] → L-glutamate[mitochondrial lumen] + NADH[mitochondrial lumen] + H+[mitochondrial lumen] ,
geranial ↔ neral ,
dopaquinone → leucodopachrome + H+ ,
neopinone → codeinone ,
5S hydro(peroxy),18R-hydroxy-eicosapentaenoate + a reduced electron acceptor → resolvin E2 + an oxidized electron acceptor + H2O ,
17S-hydro(p)docosahexaenoate + a reduced electron acceptor + oxygen → 4S-hydroperoxy,17S-H-docosahexaenoate + an oxidized electron acceptor + H2O ,
3,3',5'-triiodothyronamine + a reduced electron acceptor → 3,3'-diiodothyronamine + iodide + an oxidized electron acceptor + H+ ,
15S-hydroxypentaenoate + oxygen → lipoxin B4 ,
betaine aldehyde hydrate ↔ betaine aldehyde + H2O ,
glycine + a tetrahydrofolate + NAD+ → a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH ,
2-oxoglutaramate → 2-hydroxy-5-oxoproline ,
2 indoxyl + oxygen → indigo + 2 H2O


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Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
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