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Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
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Homo sapiens Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: n-propanol + NAD+ = propanal + NADH + H+ ,
1.1.1.1: 3-methoxy-4-hydroxyphenylglycol + NAD+ ↔ 3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: methionol + NAD+ = 3-methylthiopropanal + NADH + H+ ,
1.1.1.1: 3,4-dihydroxyphenylglycol + NAD+ ← 3,4-dihydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 4-tyrosol + NAD+ = (4-hydroxyphenyl)acetaldehyde + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: isobutanol + NAD+ ↔ isobutanal + NADH + H+ ,
1.1.1.1: phytol + NAD+ → phytenal + NADH + H+ ,
1.1.1.1: 2-methylbutanol + NAD+ = 2-methylbutanal + NADH + H+ ,
1.1.1.1: a secondary alcohol + NAD+ = a ketone + NADH + H+ ,
1.1.1.1: 5-hydroxytryptophol + NAD+ ← 5-hydroxyindole acetaldehyde + NADH + H+ ,
1.1.1.1: 2-phenylethanol + NAD+ = phenylacetaldehyde + NADH + H+ ,
1.1.1.1: indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ ,
1.1.1.1: a primary alcohol + NAD+ = an aldehyde + NADH + H+ ,
1.1.1.1: 3-methylbutanol + NAD+ ↔ 3-methylbutanal + NADH + H+ ,
1.1.1.2: indole acetaldehyde + NADPH + H+ → indole-3-ethanol + NADP+ ,
1.1.1.2: ethanol + NADP+ = acetaldehyde + NADPH + H+ ,
1.1.1.2: an alcohol + NADP+ = an aldehyde + NADPH + H+ ,
1.1.1.8: sn-glycerol 3-phosphate + NAD+ ↔ dihydroxyacetone phosphate + NADH + H+ ,
1.1.1.9: xylitol + NAD+ = D-xylulose + NADH + H+ ,
1.1.1.10: xylitol + NADP+ ↔ L-xylulose + NADPH + H+ ,
1.1.1.14: L-iditol + NAD+ = keto-L-sorbose + NADH + H+ ,
1.1.1.14: D-sorbitol + NAD+ → keto-D-fructose + NADH + H+ ,
1.1.1.19: L-gulonate + NADP+aldehydo-D-glucuronate + NADPH + H+ ,
1.1.1.21: a sugar alcohol + NAD(P)+ = an aldose + NAD(P)H + H+ ,
1.1.1.21: L-arabitol + NADP+ ↔ L-arabinopyranose + NADPH + H+ ,
1.1.1.21: galactitol + NADP+ ↔ β-D-galactose + NADPH + H+ ,
1.1.1.22: UDP-α-D-glucose + 2 NAD+ + H2O → UDP-α-D-glucuronate + 2 NADH + 3 H+ ,
1.1.1.27: (S)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.29: D-glycerate + NAD+ = hydroxypyruvate + NADH + H+ ,
1.1.1.30: (R)-3-hydroxybutanoate + NAD+ ↔ acetoacetate + NADH + H+ ,
1.1.1.31: (S)-3-hydroxy-isobutanoate + NAD+ → (S)-methylmalonate-semialdehyde + NADH + H+ ,
1.1.1.34: (R)-mevalonate + coenzyme A + 2 NADP+ ← (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ ,
1.1.1.35: (S)-3-hydroxydecanoyl-CoA + NAD+ = 3-oxodecanoyl-CoA + NADH + H+ ,
1.1.1.35: a (3S)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.35: (S)-3-hydroxybutanoyl-CoA + NAD+ ↔ acetoacetyl-CoA + NADH + H+ ,
1.1.1.36: (R)-3-hydroxybutanoyl-CoA + NADP+ = acetoacetyl-CoA + NADPH + H+ ,
1.1.1.36: (R)-3-hydroxyvaleryl-CoA + NADP+ = β-ketovaleryl-CoA + NADPH + H+ ,
1.1.1.36: a (3R)-3-hydroxyacyl-CoA + NADP+ = a 3-oxoacyl-CoA + NADPH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ = pyruvate + CO2 + NADH ,
1.1.1.40: (S)-malate + NADP+ = CO2 + pyruvate + NADPH ,
1.1.1.41: D-threo-isocitrate[mitochondrial lumen] + NAD+[mitochondrial lumen] → CO2[mitochondrial lumen] + 2-oxoglutarate[mitochondrial lumen] + NADH[mitochondrial lumen] ,
1.1.1.42: D-threo-isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.45: L-gulonate + NAD+ → 3-keto-L-gulonate + NADH + H+ ,
1.1.1.47: D-glucopyranose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+ ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.50/1.1.1.209/1.1.1.213: androsterone + NAD(P)+ = 5α-androstane-3,17-dione + NAD(P)H + H+ ,
1.1.1.51: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+ ,
1.1.1.62: 17β-estradiol + NAD(P)+ → estrone + NAD(P)H + H+ ,
1.1.1.64: testosterone + NADP+ ← androst-4-ene-3,17-dione + NADPH + H+ ,
1.1.1.71: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ ,
1.1.1.77: (R)-propane-1,2-diol + NAD+ ← (R)-lactaldehyde + NADH + H+ ,
1.1.1.78: (R)-lactaldehyde + NAD+ ← methylglyoxal + NADH + H+ ,
1.1.1.79: glycolate + NADP+ = glyoxylate + NADPH + H+ ,
1.1.1.80: isopropanol + NADP+ → acetone + NADPH + H+ ,
1.1.1.81: D-glycerate + NAD(P)+ = hydroxypyruvate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.102: sphinganine + NADP+ ← 3-dehydrosphinganine + NADPH + H+ ,
1.1.1.105: all-trans-retinol + NAD+all-trans-retinal + NADH + H+ ,
1.1.1.105: an all-trans retinol-[cellular-retinol-binding-protein] + NAD+ → an all-trans retinal-[cellular-retinol-binding-protein] + NADH + H+ ,
1.1.1.112: 1-indanol + NAD(P)+ = indanone + NAD(P)H + H+ ,
1.1.1.141: prostaglandin E2 + NAD+ = (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprosta-13-enoate + NADH + H+ ,
1.1.1.145: 17-α-hydroxypregnenolone + NAD+ = pregn-5-ene-3,20-dione-17-ol + NADH + H+ ,
1.1.1.145: pregnenolone + NAD+ → pregn-5-ene-3,20-dione + NADH + H+ ,
1.1.1.145: a 3β-hydroxy-δ5-steroid + NAD+ = a 3-oxo-δ5-steroid + NADH + H+ ,
1.1.1.145: dehydroepiandrosterone + NAD+ → 5-androstene-3,17-dione + NADH + H+ ,
1.1.1.146: an 11-β-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+ ,
1.1.1.149: (20S)-17,20-dihydroxypregn-4-en-3-one + NAD(P)+ = 17-α-hydroxyprogesterone + NAD(P)H + H+ ,
1.1.1.153: L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP+ ← 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ ,
1.1.1.153: L-erythro-7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+ ,
1.1.1.170: 4α-carboxy-5α-cholesta-8-en-3β-ol + NAD(P)+ → 5α-cholesta-8-en-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ → 3-dehydro-4-methylzymosterol + CO2 + NAD(P)H ,
1.1.1.170: 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + NAD(P)+ = CO2 + 4α-methyl-5α-cholest-7-en-3-one + NAD(P)H ,
1.1.1.170: 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ → 5α-cholesta-8,24-dien-3-one + CO2 + NAD(P)H ,
1.1.1.170: 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ → 4α-methyl-5α-cholesta-8-en-3-one + CO2 + NAD(P)H ,
1.1.1.178: 2-methyl-3-hydroxybutyryl-CoA + NAD+ → 2-methylacetoacetyl-CoA + NADH + H+ ,
1.1.1.179: a D-xylopyranose + NADP+ ↔ D-xylonolactone + NADPH + H+ ,
1.1.1.181: 7α-hydroxycholesterol + NAD+ → 7α-hydroxycholest-4-en-3-one + NADH + H+ ,
1.1.1.184: a secondary alcohol + NADP+ = a ketone + NADPH + H+ ,
1.1.1.188: prostaglandin F + NADP+ = prostaglandin D2 + NADPH + H+ ,
1.1.1.189: prostaglandin F + NADP+ = prostaglandin E2 + NADPH + H+ ,
1.1.1.197: (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoate + NADP+ = (13E)-11-α-hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.210: 5-α-androstan-3β,17β-diol + NADP+ = 5-α-dihydrotestosterone + NADPH + H+ ,
1.1.1.211: a long-chain (3S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.213: 5β-cholestane-3α,7α,12α-triol + NAD(P)+ ← 7α,12α-dihydroxy-5β-cholestan-3-one + NAD(P)H + H+ ,
1.1.1.213: allopregnanolone + NAD(P)+ ↔ 5-α-pregnane-3,20-dione + NAD(P)H + H+ ,
1.1.1.213: 5-α-androstan-3α,17β-diol + NAD(P)+ = 5-α-dihydrotestosterone + NAD(P)H + H+ ,
1.1.1.213: 5β-cholestane-3α,7α-diol + NAD(P)+ ← 7α-hydroxy-5β-cholestan-3-one + NAD(P)H + H+ ,
1.1.1.216: (2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ ,
1.1.1.218: morphine + NAD(P)+ ← morphinone + NAD(P)H + H+ ,
1.1.1.225: chlordecone alcohol + NADP+ = chlordecone + NADPH + H+ ,
1.1.1.237: 3-(4-hydroxyphenyl)lactate + NAD+ ← 4-hydroxyphenylpyruvate + NADH + H+ ,
1.1.1.239: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH + H+ ,
1.1.1.247: codeine + NADP+ ← codeinone + NADPH + H+ ,
1.1.1.248: salutaridinol + NADP+ ← salutaridine + NADPH + H+ ,
1.1.1.263: 1,5-anhydro-D-glucitol + NADP+ ← 1,5-anhydro-D-fructose + NADPH + H+ ,
1.1.1.270: 4α-methyl-cholesta-8-enol + NADP+ ← 4α-methyl-5α-cholesta-8-en-3-one + NADPH + H+ ,
1.1.1.270: zymosterol + NADP+ ← 5α-cholesta-8,24-dien-3-one + NADPH + H+ ,
1.1.1.270: 4α-methyl-5α-cholest-7-en-3β-ol + NADP+ = 4α-methyl-5α-cholest-7-en-3-one + NADPH + H+ ,
1.1.1.270: zymostenol + NADP+ ← 5α-cholesta-8-en-3-one + NADPH + H+ ,
1.1.1.270: 4α-methyl-zymosterol + NADP+ ← 3-dehydro-4-methylzymosterol + NADPH + H+ ,
1.1.1.271: GDP-β-L-fucose + NADP+ ← GDP-4-dehydro-α-D-rhamnose + NADPH + H+ ,
1.1.1.278: allopregnanolone + NADP+ = 5-α-pregnane-3,20-dione + NADPH + H+ ,
1.1.1.284: S-hydroxymethylglutathione + NAD(P)+S-formylglutathione + NAD(P)H + H+ ,
1.1.1.300: all-trans-retinol + NADP+all-trans-retinal + NADPH + H+ ,
1.1.1.315: an 11-cis-retinol-[retinal-binding protein] + NAD+ → an 11-cis-retinal-[retinal-binding protein] + NADH + H+ ,
1.1.1.330: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain oxoacyl-CoA + NADPH + H+ ,
1.1.1.330: 3R-hydroxy-tetracosapentaenoyl-CoA + NADP+ ← 3-oxo-tetracosapentaenoyl-CoA + NADPH + H+ ,
1.1.1.330: 3R-hydroxy-(11Z,14Z)-icosa-11,14-dienoyl-CoA + NADP+ ← 3-oxo-(11Z,14Z)-icosa-11,14-dienoyl-CoA + NADPH + H+ ,
1.1.1.330: 3-oxo-docosapentaenoyl-CoA + NAD(P)H + H+ → (5Z,8Z,11Z,14Z,17Z)-3R-hydroxy-docosapentaenoyl-CoA + NAD(P)+ ,
1.1.1.330: 3-oxo-icosatetraenoyl-CoA + NAD(P)H + H+ → 3-hydroxy-eicosatetraenoyl-CoA + NAD(P)+ ,
1.1.1.-: (R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: cholate + NAD+ = 3-dehydrocholate + NADH + H+ ,
1.1.1.-: 11-cis-retinol + NADP+ = 11-cis-retinal + NADPH + H+ ,
1.1.1.-: butanal + NADH + H+ → n-butanol + NAD+ ,
1.1.1.-: trans-2-hexenol + NADP+ = trans-2-hexenal + NADPH + H+ ,
1.1.1.-: (6E)-8-hydroxygeranial + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ,
1.1.1.-: 9-cis-retinol + NAD+ = 9-cis-retinal + NADH + H+ ,
1.1.1.-: a (3R)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.-: (6E)-8-oxogeraniol + NADP+ = (6E)-8-oxogeranial + NADPH + H+ ,
1.1.1.-: 13-cis-retinol + NAD+ → 13-cis-retinal + NADH + H+ ,
1.1.1.-: (3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD+ → 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADH + H+ ,
1.1.1.-: 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: trans-2-pentenol + NADP+ = trans-2-pentenal + NADPH + H+ ,
1.1.1.-: acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
1.1.1.-: n-butanol + NADP+ = butanal + NADPH + H+ ,
1.1.1.-: choloyl-CoA + NAD(P)+ = 3-oxo-cholyl-CoA + NAD(P)H + H+ ,
1.1.3.15: an (S)-2-hydroxyacid + oxygen → hydrogen peroxide + a 2-oxo carboxylate ,
1.1.3.-: glycolate + oxygen → glyoxylate + hydrogen peroxide ,
1.1.5.3: sn-glycerol 3-phosphate[mitochondrial intermembrane space] + an ubiquinone[mitochondrial inner membrane] → dihydroxyacetone phosphate[mitochondrial intermembrane space] + an ubiquinol[mitochondrial inner membrane] ,
1.1.5.-: (R)-lactate + an ubiquinone[inner membrane] → pyruvate + an ubiquinol[inner membrane] ,
1.1.99.1: choline + an unknown oxidized electron acceptor → betaine aldehyde + an unknown reduced electron acceptor ,
1.1.99.2: (S)-2-hydroxyglutarate + an unknown oxidized electron acceptor = 2-oxoglutarate + an unknown reduced electron acceptor ,
1.1.99.14: glycolate + an unknown oxidized electron acceptor = glyoxylate + an unknown reduced electron acceptor ,
1.1.99.24: (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate ,
1.1.-.-: allopregnanolone[cytosol] + NAD+[cytosol] → 5-α-pregnane-3,20-dione[cytosol] + NADH[cytosol] + H+[cytosol] ,
1.2.1.3: 3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O → 3,4-dihydroxymandelate + NADH + 2 H+ ,
1.2.1.3: a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+ ,
1.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O → an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: octanal + NAD+ + H2O = octanoate + NADH + 2 H+ ,
1.2.1.3: phytenal + NAD+ + H2O → phytenate + NADH + 2 H+ ,
1.2.1.3: 4-acetamidobutanal + NAD+ + H2O → 4-acetamidobutanoate + NADH + 2 H+ ,
1.2.1.3: imidazole acetaldehyde + NAD+ + H2O → 4-imidazoleacetate + NADH + 2 H+ ,
1.2.1.3: 3-methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O → vanillyl mandelate + NADH + 2 H+ ,
1.2.1.3: a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O → a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: indole acetaldehyde + NAD+ + H2O → indole-3-acetate + NADH + 2 H+ ,
1.2.1.3: 3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O → 3,4-dihydroxyphenylacetate + NADH + 2 H+ ,
1.2.1.3: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ ,
1.2.1.3: 5-hydroxyindole acetaldehyde + NAD+ + H2O → 5-hydroxyindole acetate + NADH + 2 H+ ,
1.2.1.3: an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + 2 H+ ,
1.2.1.5: an aldehyde + NAD(P)+ + H2O = a carboxylate + NAD(P)H + 2 H+ ,
1.2.1.5: indole acetaldehyde + NAD(P)+ + H2O = indole-3-acetate + NAD(P)H + 2 H+ ,
1.2.1.8: betaine aldehyde + NAD+ + H2O → glycine betaine + NADH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ → acetyl-CoA + NADH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.18: malonate semialdehyde + coenzyme A + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H ,
1.2.1.19: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+ ,
1.2.1.22: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+ ,
1.2.1.24: succinate semialdehyde + NAD+ + H2O → succinate + NADH + 2 H+ ,
1.2.1.25: 3-methyl-2-oxobutanoate + coenzyme A + NAD+ → isobutanoyl-CoA + CO2 + NADH ,
1.2.1.27: (S)-methylmalonate-semialdehyde + coenzyme A + NAD+ + H2O → propanoyl-CoA + hydrogen carbonate + NADH + H+ ,
1.2.1.27: methylmalonate semialdehyde + coenzyme A + NAD+ + H2O = propanoyl-CoA + hydrogen carbonate + NADH + H+ ,
1.2.1.31: (S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O → L-2-aminoadipate + NAD(P)H + 2 H+ ,
1.2.1.32: 2-aminomuconate 6-semialdehyde + NAD+ + H2O → 2-aminomuconate + NADH + 2 H+ ,
1.2.1.36: an all-trans retinal-[cellular-retinol-binding-protein] + NAD+ + H2O → all-trans-retinoate + a cellular-retinol-binding protein + NADH + H+ ,
1.2.1.36: all-trans-retinal + NAD+ + H2O = all-trans-retinoate + NADH + 2 H+ ,
1.2.1.39: phenylacetaldehyde + NAD+ + H2O → phenylacetate + NADH + 2 H+ ,
1.2.1.41: L-glutamate-5-semialdehyde[mitochondrial lumen] + NADP+[mitochondrial lumen] + phosphate[mitochondrial lumen] ← γ-L-glutamyl 5-phosphate[mitochondrial lumen] + NADPH[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.2.1.42: palmitaldehyde + coenzyme A + NAD+ = palmitoyl-CoA + NADH + H+ ,
1.2.1.47: 4-trimethylammoniobutanal + NAD+ + H2O → γ-butyrobetaine + NADH + 2 H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.84: a long-chain acyl-CoA + 2 NADPH + 2 H+ = a long-chain alcohol + coenzyme A + 2 NADP+ ,
1.2.1.88: L-glutamate-5-semialdehyde + NAD+ + H2O → L-glutamate + NADH + 2 H+ ,
1.2.1.-: pyruvate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + NAD+[mitochondrial lumen] = acetyl-CoA[mitochondrial lumen] + CO2[mitochondrial lumen] + NADH[mitochondrial lumen] ,
1.2.1.-: (S)-3-methyl-2-oxopentanoate + coenzyme A + NAD+ → 2-methylbutanoyl-CoA + CO2 + NADH ,
1.2.1.-: 4-methyl-2-oxopentanoate + coenzyme A + NAD+ → isovaleryl-CoA + CO2 + NADH ,
1.2.1.-: (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD+ + 2 H2O = L-2-aminoadipate + NADH + H+ ,
1.2.1.-: malonate semialdehyde + coenzyme A + NAD+ = acetyl-CoA + CO2 + NADH ,
1.2.1.-: apo-4'-lycopenal + NAD(P)+ + H2O = apo-4'-lycopenoate + NADPH + H+ ,
1.2.1.-: (S)-lactaldehyde + NADP+ + H2O = (S)-lactate + NADPH + 2 H+ ,
1.2.1.-: L-4-hydroxyglutamate semialdehyde + NAD+ + H2O → erythro-4-hydroxy-L-glutamate + NADH + 2 H+ ,
1.2.1.-: (S)-2-amino-6-oxohexanoate + NAD+ + H2O = L-2-aminoadipate + NADH + 2 H+ ,
1.2.1.-: malonate semialdehyde + coenzyme A + NADP+ = acetyl-CoA + CO2 + NADPH ,
1.2.3.1: geranial + oxygen + H2O → geranate + hydrogen peroxide + H+ ,
1.2.3.1: all-trans-retinal + H2O + oxygen → all-trans-retinoate + hydrogen peroxide + H+ ,
1.2.3.1: acetaldehyde + oxygen + H2O → acetate + hydrogen peroxide + H+ ,
1.2.3.1: an aldehyde + oxygen + H2O → a carboxylate + hydrogen peroxide + H+ ,
1.2.3.1: heptanal + oxygen + H2O → heptanoate + hydrogen peroxide + H+ ,
1.2.3.-: nicotine-Δ1'5'-iminium ion + oxygen + H2O → cotinine + hydrogen peroxide + H+ ,
1.2.99.7: an aldehyde + FAD + H2O = a carboxylate + FADH2 ,
1.3.1.2: 5,6-dihydrouracil + NADP+ ← uracil + NADPH + H+ ,
1.3.1.2: 5,6-dihydrothymine + NADP+ ← thymine + NADPH + H+ ,
1.3.1.3: 7α-hydroxycholest-4-en-3-one + NADPH + H+ → 7α-hydroxy-5β-cholestan-3-one + NADP+ ,
1.3.1.3: 4,5β-dihydrocortisone + NADP+ = cortisone + NADPH + H+ ,
1.3.1.3: 7α,12α-dihydroxycholest-4-en-3-one + NADPH + H+ → 7α,12α-dihydroxy-5β-cholestan-3-one + NADP+ ,
1.3.1.3: 5β-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ ,
1.3.1.14: (S)-dihydroorotate + NAD+ = orotate + NADH + H+ ,
1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+ ,
1.3.1.21: cholesterol + NADP+ ← 7-dehydrocholesterol + NADPH + H+ ,
1.3.1.21: desmosterol + NADP+ ← 7-dehydrodesmosterol + NADPH + H+ ,
1.3.1.22: 5α-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ ,
1.3.1.22: a 3-oxo-5-α-steroid + NADP+ = a 3-oxo-Δ4-steroid + NADPH + H+ ,
1.3.1.22: 5-α-pregnane-3,20-dione + NADP+ ← progesterone + NADPH + H+ ,
1.3.1.22: 5-α-dihydrotestosterone + NADP+ ← testosterone + NADPH + H+ ,
1.3.1.22: 4,5α-dihydrocortisone + NADP+ = cortisone + NADPH + H+ ,
1.3.1.24: bilirubin + NAD(P)+ ← biliverdin-IX-α + NAD(P)H + H+ ,
1.3.1.27: palmitaldehyde + NADP+ ← 2-trans-hexadecenal + NADPH + H+ ,
1.3.1.34: trans-Δ2-decenoyl-CoA + NADP+ = trans-Δ2, cis-Δ4-decadienoyl-CoA + NADPH + H+ ,
1.3.1.34: a 2-trans-4-cis-dienoyl-CoA + NADPH = a trans-3-enoyl-CoA + NADP+ + H+ ,
1.3.1.38: a 2,3,4-saturated fatty acyl CoA + NADP+ = a trans-2-enoyl-CoA + NADPH + H+ ,
1.3.1.38: phytenoyl-CoA + NADPH + H+ → phytanoyl-CoA + NADP+ ,
1.3.1.48: (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-α-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+ ,
1.3.1.70: 4,4-dimethyl-5α-cholesta-8-en-3-β-ol + NADP+ ← 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + NADPH + H+ ,
1.3.1.70: 4,4-dimethylzymosterol + NADP+ ← 14-demethyllanosterol + NADPH + H+ ,
1.3.1.70: 4α-methyl-5α-ergosta-8,24-dien-3β-ol + NADP+ = 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + NADPH + H+ ,
1.3.1.72: desmosterol + NADPH + H+ → cholesterol + NADP+ ,
1.3.1.72: lanosterol + NADPH + H+ → 24,25-dihydrolanosterol + NADP+ ,
1.3.1.72: lathosterol + NADP+ ← 5α-cholesta-7,24-dien-3β-ol + NADPH + H+ ,
1.3.1.93: (2E,8Z,11Z,14Z,17Z)-icosa-2,8,11,14,17-pentaenoyl-CoA + an unknown reduced electron acceptor → eicosatetraenoyl-CoA + an unknown oxidized electron acceptor ,
1.3.1.93: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP+ ← (2Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADPH + H+ ,
1.3.1.93: a very-long-chain 2,3,4-saturated fatty acyl CoA + NADP+ = a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ ,
1.3.1.93: (11Z,14Z)-icosa-11,14-dienoyl-CoA + NADP+ ← (2E, 11Z,14Z)-icosa-2,11,14-trienoyl-CoA + NADPH + H+ ,
1.3.1.93: (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + an unknown reduced electron acceptor → docosapentaenoyl-CoA + an unknown oxidized electron acceptor ,
1.3.1.94: a ditrans,polycis-dolichol + NADP+ = a di-trans, poly-cis-polyprenol + NADPH + H+ ,
1.3.1.96: squalene + NADP+ + diphosphate = presqualene diphosphate + NADPH + H+ ,
1.3.1.-: progesterone + NADPH + H+ = 5-β-pregnan-3,20 dione + NADP+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.3.6: a 2,3,4-saturated fatty acyl CoA + oxygen → a trans-2-enoyl-CoA + hydrogen peroxide ,
1.3.3.6: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + oxygen → (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + hydrogen peroxide ,
1.3.3.6: an acyl-CoA + oxygen → a trans-2-enoyl-CoA + hydrogen peroxide ,
1.3.5.1: succinate[mitochondrial lumen] + an ubiquinone[mitochondrial inner membrane] → fumarate[mitochondrial lumen] + an ubiquinol[mitochondrial inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an electron-transfer quinone[inner membrane] → orotate + an electron-transfer quinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an ubiquinone[inner membrane] → orotate + an ubiquinol[inner membrane] ,
1.3.8.4: isovaleryl-CoA + an oxidized electron-transfer flavoprotein → 3-methylcrotonyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.5: 2-methylbutanoyl-CoA + an oxidized electron-transfer flavoprotein → (E)-2-methylcrotonoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.6: glutaryl-CoA + an oxidized electron-transfer flavoprotein = crotonyl-CoA + CO2 + a reduced electron-transfer flavoprotein ,
1.3.8.7: decanoyl-CoA + an oxidized electron-transfer flavoprotein = trans-Δ2-decenoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.7: a medium-chain 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein = a medium-chain trans-2,3-dehydroacyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.8: a long-chain 2,3,4-saturated fatty acyl CoA[mitochondrial lumen] + an oxidized electron-transfer flavoprotein[mitochondrial lumen] = a long-chain trans-2,3-dehydroacyl-CoA[mitochondrial lumen] + a reduced electron-transfer flavoprotein[mitochondrial lumen] ,
1.3.8.-: a 2,3,4-saturated fatty acyl CoA[mitochondrial lumen] + an oxidized electron-transfer flavoprotein[mitochondrial lumen] + H+[mitochondrial lumen] → a trans-2-enoyl-CoA[mitochondrial lumen] + a reduced electron-transfer flavoprotein[mitochondrial lumen] ,
1.3.8.-: isobutanoyl-CoA + FAD + H+ → methylacrylyl-CoA + FADH2 ,
1.3.98.1: (S)-dihydroorotate + fumarate → orotate + succinate ,
1.3.99.6: a 3-oxo-5-β-steroid + an unknown oxidized electron acceptor = a 3-oxo-Δ4-steroid + an unknown reduced electron acceptor ,
1.3.99.12: 2-methylbutanoyl-CoA + an unknown oxidized electron acceptor = (E)-2-methylcrotonoyl-CoA + an unknown reduced electron acceptor ,
1.3.99.23: all-trans-13,14-dihydroretinol + an unknown oxidized electron acceptor = all-trans-retinol + an unknown reduced electron acceptor ,
1.3.99.-: pseudooxynicotine + oxygen + 2 H2O → 4-oxo-4-(3-pyridyl)-butanoate + methylamine + hydrogen peroxide ,
1.4.1.2: L-glutamate[mitochondrial lumen] + NAD+[mitochondrial lumen] + H2O[mitochondrial lumen] = 2-oxoglutarate[mitochondrial lumen] + ammonium[mitochondrial lumen] + NADH[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.4.1.3: L-glutamate[mitochondrial lumen] + NAD(P)+[mitochondrial lumen] + H2O[mitochondrial lumen] ↔ 2-oxoglutarate[mitochondrial lumen] + ammonium[mitochondrial lumen] + NAD(P)H[mitochondrial lumen] + H+[mitochondrial lumen] ,
1.4.1.21: L-aspartate + NAD(P)+ + H2O = oxaloacetate + ammonium + NAD(P)H + H+ ,
1.4.3.2: L-arginine + oxygen + H2O → ammonium + 2-ketoarginine + hydrogen peroxide ,
1.4.3.2: a standard α amino acid + oxygen + H2O → ammonium + hydrogen peroxide + a 2-oxo carboxylate ,
1.4.3.3: a D-amino acid + oxygen + H2O → ammonium + hydrogen peroxide + a 2-oxo carboxylate ,
1.4.3.4: a monoamine + H2O + oxygen → an aldehyde + a primary amine + hydrogen peroxide ,
1.4.3.4: 5-methoxytryptamine + H+ + H2O + oxygen → 5-methoxyindoleacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: (R)-adrenaline + H2O + oxygen → 3,4-dihydroxyphenylglycolaldehyde + methylamine + hydrogen peroxide ,
1.4.3.4: tryptamine + H2O + oxygen → ammonium + indole acetaldehyde + hydrogen peroxide ,
1.4.3.4: serotonin + oxygen + H2O → 5-hydroxyindole acetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: (R)-noradrenaline + H2O + oxygen → 3,4-dihydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: normetanephrine + H2O + oxygen → 3-methoxy-4-hydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: 2-phenylethylamine + oxygen + H2O → phenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: metanephrine + H2O + oxygen → 3-methoxy-4-hydroxyphenylglycolaldehyde + methylamine + hydrogen peroxide ,
1.4.3.4: dopamine + H2O + oxygen → 3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.4: N-acetylputrescine + H2O + oxygen → 4-acetamidobutanal + ammonium + hydrogen peroxide ,
1.4.3.5: pyridoxamine 5'-phosphate + oxygen + H2O → ammonium + hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.13: a [protein]-L-lysine + oxygen + H2O → a protein L-allysine + ammonium + hydrogen peroxide ,
1.4.3.21: an aliphatic amine + H2O + oxygen → an aldehyde + ammonium + hydrogen peroxide ,
1.4.3.21: a primary amine + H2O + oxygen → an aldehyde + ammonium + hydrogen peroxide ,
1.4.3.21: cadaverine + H2O + oxygen → 5-aminopentanal + ammonium + hydrogen peroxide ,
1.4.3.21: aminoacetone + H2O + oxygen → methylglyoxal + ammonium + hydrogen peroxide ,
1.4.3.21: 2-phenylethylamine + oxygen + H2O → phenylacetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.22: histamine + H2O + oxygen → imidazole acetaldehyde + ammonium + hydrogen peroxide ,
1.4.3.22: a diamine + H2O + oxygen → a monoamine + ammonium + hydrogen peroxide ,
1.4.3.-: L-tryptophan + oxygen → 2-imino-3-(indol-3-yl)propanoate + hydrogen peroxide + H+ ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.2: trans-4-hydroxy-L-proline + NAD(P)+ ← (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: a tetrahydrofolate + NADP+ ← a 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: a 5,10-methylene-tetrahydrofolate + NADP+ ↔ a 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.6: an N10-formyl-tetrahydrofolate + NADP+ + H2O = a tetrahydrofolate + CO2 + NADPH + H+ ,
1.5.1.8: L-saccharopine + NADP+ + H2O ← 2-oxoglutarate + L-lysine + NADPH + H+ ,
1.5.1.9: L-saccharopine + NAD+ + H2O → L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+ ,
1.5.1.15: a 5,10-methylene-tetrahydrofolate + NAD+ → a 5,10-methenyltetrahydrofolate + NADH ,
1.5.1.20: an N5-methyl-tetrahydrofolate + NAD+ ← a 5,10-methylene-tetrahydrofolate + NADH + H+ ,
1.5.1.21: L-pipecolate + NAD(P)+ ← Δ1-piperideine-2-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.21: L-pipecolate + NADP+ ← (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NADPH + 2 H+ ,
1.5.1.25: thiomorpholine-3-carboxylate + NAD(P)+ = 3,4-dehydrothiomorpholine-3-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.27: (R)-reticuline + NADP+ ← 1,2-dehydroreticulinium + NADPH + H+ ,
1.5.1.30: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+ ,
1.5.1.34: a 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H+ ,
1.5.1.38: NADP+ + FMNH2 = NADPH + FMN + 2 H+ ,
1.5.1.39: FMNH2 + NAD(P)+ = FMN + NAD(P)H + 2 H+ ,
1.5.1.-: tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ ,
1.5.1.-: L-erythro-7,8-dihydrobiopterin + NADH + H+ → L-erythro-5,6,7,8-tetrahydrobiopterin + NAD+ ,
1.5.3.1: sarcosine + oxygen + H2O → hydrogen peroxide + formaldehyde + glycine ,
1.5.3.2: N-methyl-L-tryptophan + oxygen + H2O → hydrogen peroxide + formaldehyde + L-tryptophan ,
1.5.3.7: L-pipecolate + oxygen → (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + hydrogen peroxide + H+ ,
1.5.3.13: N1,N12-diacetylspermine + oxygen + H2O → N1-acetylspermidine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.13: N1-acetylspermine + oxygen + H2O → spermidine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.13/1.5.3.17: N1-acetylspermidine + oxygen + H2O → putrescine + 3-acetamidopropanal + hydrogen peroxide ,
1.5.3.14: spermine + oxygen + H2O → 1-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide ,
1.5.3.16: N1-acetylspermine + oxygen + H2O → hydrogen peroxide + 3-aminopropanal + N1-acetylspermidine ,
1.5.3.16: norspermine + oxygen + H2O → norspermidine + 3-aminopropanal + hydrogen peroxide ,
1.5.3.17: spermine + H2O + oxygen → 3-aminopropanal + spermidine + hydrogen peroxide ,
1.5.5.2: L-proline[in] + an ubiquinone[in] → (S)-1-pyrroline-5-carboxylate[in] + an ubiquinol[in] + H+[in] ,
1.5.5.2: L-proline[in] + an ubiquinone[in] → (S)-1-pyrroline-5-carboxylate[in] + an ubiquinol[in] + H+[in] ,
1.5.5.2: L-proline[in] + an electron-transfer quinone[membrane] → (S)-1-pyrroline-5-carboxylate[in] + an electron-transfer quinol[membrane] + H+[in] ,
1.5.5.-: trans-4-hydroxy-L-proline[in] + an electron-transfer quinone[membrane] → (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate[in] + an electron-transfer quinol[membrane] + H+[in] ,
1.5.8.3: sarcosine + an oxidized electron-transfer flavoprotein + H2O + H+ = glycine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.8.4: dimethylglycine + an oxidized electron-transfer flavoprotein + H2O + H+ = sarcosine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.8.-: (S)-nicotine + an oxidized flavoprotein → nicotine-Δ1'5'-iminium ion + a reduced flavoprotein ,
1.5.8.-: sarcosine + an oxidized electron-transfer flavoprotein + a tetrahydrofolate → glycine + a 5,10-methenyltetrahydrofolate + a reduced electron-transfer flavoprotein ,
1.5.8.-: dimethylglycine + an oxidized electron-transfer flavoprotein + a tetrahydrofolate → sarcosine + a 5,10-methenyltetrahydrofolate + a reduced electron-transfer flavoprotein ,
1.6.1.2/1.6.1.3: NADPH + NAD+ = NADH + NADP+ ,
1.6.1.2: NADH + NADP+ + H+[out] → NADPH + NAD+ + H+[in] ,
1.6.3.1: NAD(P)H + H+ + oxygen → hydrogen peroxide + NAD(P)+ ,
1.6.3.5: 2-dihydro-NAD + H+ + oxygen = hydrogen peroxide + NAD+ ,
1.6.3.5: 2-dihydro-NADP + H+ + oxygen → hydrogen peroxide + NADP+ ,
1.6.3.5: 6-dihydro-NAD + H+ + oxygen = hydrogen peroxide + NAD+ ,
1.6.3.5: 6-dihydro-NADP + H+ + oxygen = hydrogen peroxide + NADP+ ,
1.6.5.2: a plastoquinone + NAD(P)H + H+ ↔ a plastoquinol + NAD(P)+ ,
1.6.5.2: a quinone[membrane] + NAD(P)H[membrane] + H+[membrane] → a quinol[membrane] + NAD(P)+[membrane] ,
1.6.5.3: NADH[mitochondrial lumen] + an ubiquinone[mitochondrial inner membrane] + 5 H+[mitochondrial lumen] ↔ NAD+[mitochondrial lumen] + an ubiquinol[mitochondrial inner membrane] + 4 H+[mitochondrial intermembrane space] ,
1.6.5.4: 2 monodehydroascorbate radical + NADH → 2 L-ascorbate + NAD+ + H+ ,
1.6.5.5: a quinone + NADPH = a semiquinone + NADP+ ,
1.6.5.9: NADH + an ubiquinone[inner membrane] + H+ → NAD+ + an ubiquinol[inner membrane] ,
1.6.5.10: NADPH[membrane] + an electron-transfer quinone[membrane] + H+[membrane] = NADP+[membrane] + an electron-transfer quinol[membrane] ,
1.6.5.-: 2 monodehydroascorbate radical + NADPH + H+ → 2 L-ascorbate + NADP+ + 2 H+ ,
1.6.99.3: NADH + an unknown oxidized electron acceptor + H+ = NAD+ + an unknown reduced electron acceptor ,
1.7.1.7: ammonium + IMP + NADP+ = GMP + NADPH + 2 H+ ,
1.8.1.3: hypotaurine + NAD+ + H2O → taurine + NADH + H+ ,
1.8.1.7: 2 glutathione + NADP+ ← glutathione disulfide + NADPH + H+ ,
1.8.1.8: a protein dithiol + NAD(P)+ = a protein disulfide + NAD(P)H + H+ ,
1.8.3.1: sulfite + oxygen + H2O → hydrogen peroxide + sulfate ,
1.8.3.2: 2 R'C(R)SH + oxygen → R'C(R)S-S(R)CR' + hydrogen peroxide ,
1.8.3.5: S-prenyl-L-cysteine + H2O + oxygen → 3-methyl-2-butenal + hydrogen peroxide + L-cysteine ,
1.8.3.6: S-(2E,6E)-farnesyl-L-cysteine + oxygen + H2O → (2E,6E)-farnesal + L-cysteine + hydrogen peroxide ,
1.8.3.-: a [sulfatase]-L-cysteine + 2 a thiol + oxygen → a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O ,
1.8.4.2: 2 glutathione + a protein disulfide = glutathione disulfide + a protein dithiol ,
1.8.4.3: glutathione disulfide + coenzyme A = glutathione + CoA-glutathione ,
1.8.5.1: L-dehydro-ascorbate + 2 glutathione → L-ascorbate + glutathione disulfide + H+ ,
1.8.5.4: hydrogen sulfide + an electron-transfer quinone = intracellular S0 + an electron-transfer quinol ,
1.8.98.2: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + a protein dithiol = peroxiredoxin-(S-hydroxycysteine) + ADP + a protein disulfide + phosphate + H+ ,
1.9.3.1/1.10.2.2: 2 an ubiquinol[mitochondrial inner membrane] + oxygen[mitochondrial lumen] + 12 H+[mitochondrial lumen] → 2 an ubiquinone[mitochondrial inner membrane] + 2 H2O[mitochondrial lumen] + 12 H+[mitochondrial intermembrane space] ,
1.10.3.1: 2 catechol + oxygen → 2 1,2-benzoquinone + 2 H2O ,
1.10.3.1: 2 cis-caffeate + oxygen → 2 3-(2-propenoic acid)-o-benzoquinone + 2 H2O ,
1.10.3.-: L-dopa + 0.5 oxygen → dopaquinone + H2O ,
1.10.99.2: 1-(β-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H+ = a quinol + 1-(β-D ribofuranosyl)nicotinamide ,
1.11.1.6: ethanol + hydrogen peroxide → acetaldehyde + 2 H2O ,
1.11.1.7: a phenolic donor + hydrogen peroxide = 2 a phenoxyl radical of a phenolic donor + 2 H2O ,
1.11.1.7: 2 betanidin + hydrogen peroxide = betanidin + betanidin quinone + 2 H2O ,
1.11.1.8: [thyroglobulin]-3-iodotyrosine + iodide + hydrogen peroxide + H+ → [thyroglobulin]-3,5-diiodotyrosine + 2 H2O ,
1.11.1.8: hydrogen peroxide + 2 iodide + 2 H+ = I2 + 2 H2O ,
1.11.1.8: [thyroglobulin]-L-tyrosine + hydrogen peroxide + iodide + H+ → [thyroglobulin]-3-iodotyrosine + 2 H2O ,
1.11.1.8: 2 [thyroglobulin]-3,5-diiodotyrosine + hydrogen peroxide → [thyroglobulin]-L-thyroxine + [thyroglobulin]-aminoacrylate + 2 H2O ,
1.11.1.8: [thyroglobulin]-3-iodotyrosine + [thyroglobulin]-3,5-diiodotyrosine + hydrogen peroxide → [thyroglobulin]-triiodothyronine + [thyroglobulin]-aminoacrylate + 2 H2O ,
1.11.1.9: hydrogen peroxide + 2 glutathione → glutathione disulfide + 2 H2O ,
1.11.1.11: 2 L-ascorbate + hydrogen peroxide + H+ → L-ascorbate + L-dehydro-ascorbate + 2 H2O ,
1.11.1.12: a hydroperoxy fatty acid in a glycerolipid + 2 glutathione + H+ → a lipid + glutathione disulfide + 2 H2O ,
1.11.1.15: 2 protein cysteines + an organic hydroperoxide = a protein disulfide + an alcohol + H2O ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.11.2.2: chloride + hydrogen peroxide + H+ = hypochlorous acid + H2O ,
1.13.11.5: homogentisate + oxygen → 4-maleyl-acetoacetate + H+ ,
1.13.11.6: 3-hydroxyanthranilate + oxygen → aminocarboxymuconate semialdehyde + H+ ,
1.13.11.11/1.13.11.52: L-tryptophan + oxygen → N-formylkynurenine ,
1.13.11.19: cysteamine + oxygen → hypotaurine + H+ ,
1.13.11.20: L-cysteine + oxygen → 3-sulfinoalanine + H+ ,
1.13.11.27: 2-oxo-3-phenylpropanoate + oxygen → 2-hydroxyphenylacetate + CO2 ,
1.13.11.27: 4-hydroxyphenylpyruvate + oxygen → CO2 + homogentisate ,
1.13.11.31: arachidonate + oxygen → (12S)-HPETE ,
1.13.11.33: arachidonate + oxygen → (15S)-HPETE ,
1.13.11.34: arachidonate + oxygen → leukotriene A4 + H2O ,
1.13.11.52: D-tryptophan + oxygen → N-formyl-D-kynurenine ,
1.13.11.53: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 3-(methylthio)propanoate + formate + carbon monoxide + H+ ,
1.13.11.54: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 2-oxo-4-methylthiobutanoate + formate + H+ ,
1.13.11.63: all-trans-β-carotene + oxygen → 2 all-trans-retinal ,
1.13.11.71: all-trans-β-carotene + oxygen → all-trans-10'-apo-β-carotenal + β-ionone ,
1.13.11.-: all-trans-10'-apo-β-carotenal + oxygen → β-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaene-1,12-dial ,
1.13.11.-: leukotriene A4 + an unknown reduced electron acceptor + oxygen → lipoxin B4 + an unknown oxidized electron acceptor ,
1.13.11.-: leukotriene A4 + an unknown reduced electron acceptor + oxygen → lipoxin A4 + an unknown oxidized electron acceptor ,
1.13.11.-: all-trans-β-carotene + 2 oxygen → 2 β-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaene-1,12-dial ,
1.13.11.-: 4-methyl-2-oxopentanoate + oxygen → 3-hydroxyisovalerate + CO2 ,
1.13.99.1: myo-inositol + oxygen → D-glucopyranuronate + H+ + H2O ,
1.14.11.1: 2-oxoglutarate + γ-butyrobetaine + oxygen → L-carnitine + CO2 + succinate ,
1.14.11.2: a [procollagen]-L-proline + 2-oxoglutarate + oxygen → a [procollagen] trans 4-hyroxy-L-proline + CO2 + succinate ,
1.14.11.4: a [procollagen]-L-lysine + 2-oxoglutarate + oxygen → a [procollagen]-5-hydroxy-L-lysine + CO2 + succinate ,
1.14.11.7: a [procollagen]-L-proline + 2-oxoglutarate + oxygen → a [procollagen]-3-hydroxy-L-proline + CO2 + succinate ,
1.14.11.8: 2-oxoglutarate + N6,N6,N6-trimethyl-L-lysine + oxygen → CO2 + succinate + 3-hydroxy-N6,N6,N6-trimethyl-L-lysine ,
1.14.11.16: a [protein]-L-aspartate + 2-oxoglutarate + oxygen → CO2 + succinate + a [protein]-3-hydroxy-L-aspartate ,
1.14.11.18: 2-oxoglutarate + phytanoyl-CoA + oxygen → CO2 + succinate + 2-hydroxyphytanoyl-CoA ,
1.14.11.31: thebaine + 2-oxoglutarate + oxygen → neopinone + formaldehyde + succinate + CO2 ,
1.14.11.31: oripavine + 2-oxoglutarate + oxygen → morphinone + formaldehyde + succinate + CO2 ,
1.14.11.32: thebaine + 2-oxoglutarate + oxygen → oripavine + formaldehyde + succinate + CO2 ,
1.14.11.32: codeine + 2-oxoglutarate + oxygen → morphine + formaldehyde + succinate + CO2 ,
1.14.11.33: a methylated nucleobase within DNA + 2-oxoglutarate + oxygen → a nucleobase within DNA + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: N3-methylcytosine + 2-oxoglutarate + oxygen → cytosine + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: N1-methyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + formaldehyde + succinate ,
1.14.11.33: 1-ethyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + acetaldehyde + succinate ,
1.14.11.42: 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + 2-oxoglutarate + oxygen → 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe + succinate + CO2 ,
1.14.11.-: a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + 2-oxoglutarate + oxygen → a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA + succinate + CO2 ,
1.14.11.-: a [protein] N6-methyl-L-lysine + 2-oxoglutarate + oxygen + H+ → a [protein]-L-lysine + succinate + formaldehyde + CO2 ,
1.14.13.8: (S)-nicotine + NADPH + oxygen → nicotine-1'-N-oxide + NADP+ + H2O ,
1.14.13.8: N,N-dimethylaniline + NADPH + oxygen + H+N,N-dimethylaniline-N-oxide + NADP+ + H2O ,
1.14.13.9: L-kynurenine + NADPH + oxygen + H+ → 3-hydroxy-L-kynurenine + NADP+ + H2O ,
1.14.13.13: calcidiol + NADPH + H+ + oxygen → calcitriol + NADP+ + H2O ,
1.14.13.15: 5β-cholestane-3α,7α,12α-triol + 3 NADPH + 2 H+ + 3 oxygen → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + 3 NADP+ + 4 H2O ,
1.14.13.15: 5β-cholestane-3α,7α-diol + 3 NADPH + 2 H+ + 3 oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + 3 NADP+ + 4 H2O ,
1.14.13.17: cholesterol + NADPH + H+ + oxygen → 7α-hydroxycholesterol + NADP+ + H2O ,
1.14.13.30: leukotriene B4 + NADPH + oxygen + H+ → 20-hydroxy-leukotriene B4 + NADP+ + H2O ,
1.14.13.30: α-tocopherol + NADPH + oxygen + H+ → 13'-hydroxy-α-tocopherol + NADP+ + H2O ,
1.14.13.32: albendazole + NADPH + H+ + oxygen → albendazole s-oxide + NADP+ + H2O ,
1.14.13.39: 2 L-arginine + 3 NADPH + H+ + 4 oxygen → 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O ,
1.14.13.48: (4S)-limonene + NADPH + oxygen + H+ → (-)-trans-carveol + NADP+ + H2O ,
1.14.13.49: (4S)-limonene + NADPH + oxygen + H+ → (4S)-perillyl alcohol + NADP+ + H2O ,
1.14.13.67: quinine + NADPH + H+ + oxygen → 3-hydroxyquinine + NADP+ + H2O ,
1.14.13.70: obtusifoliol + 3 NADPH + 3 oxygen + 2 H+ → formate + 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + 3 NADP+ + 4 H2O ,
1.14.13.70: 4α,14α-dimethyl-5α-cholesta-8,24-dien-3β-ol + 3 NADPH + 3 oxygen + 2 H+ → 4α-methyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 NADP+ + 4 H2O ,
1.14.13.70: 24,25-dihydrolanosterol + 3 NADPH + 3 oxygen + 2 H+ → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate + 3 NADP+ + 4 H2O ,
1.14.13.70: lanosterol + 3 NADPH + 3 oxygen + 2 H+ → 14-demethyllanosterol + formate + 3 NADP+ + 4 H2O ,
1.14.13.72: 4,4-dimethyl-5α-cholest-7-en-3β-ol + 3 NAD(P)H + 3 oxygen + 2 H+ → 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4α-methyl-cholesta-8-enol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-5α-cholesta-8-en-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4α-methyl-zymosterol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethylzymosterol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.72: 4,4-dimethyl-5α-cholesta-8-en-3-β-ol + 3 NAD(P)H + 3 oxygen + 2 H+ → 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + 3 NAD(P)+ + 4 H2O ,
1.14.13.80: (4R)-limonene + NADPH + H+ + oxygen → (+)-trans-carveol + NADP+ + H2O ,
1.14.13.95: 7α-hydroxycholest-4-en-3-one + NADPH + H+ + oxygen → 7α,12α-dihydroxycholest-4-en-3-one + NADP+ + H2O ,
1.14.13.97: lithocholate + NADPH + H+ + oxygen → hyodeoxycholate + NADP+ + H2O ,
1.14.13.97: taurochenodeoxycholate + NADPH + H+ + oxygen → taurohyocholate + NADP+ + H2O ,
1.14.13.98: cholesterol + NADPH + H+ + oxygen → (24S)-24-hydroxycholesterol + NADP+ + H2O ,
1.14.13.99: (24R)-cholest-5-ene-3β,24-diol + NADPH + H+ + oxygen → (24R)-cholest-5-ene-3β,7α,24-triol + NADP+ + H2O ,
1.14.13.100: cholest-5-ene-3β,25-diol + NADPH + H+ + oxygen → cholest-5-ene-3β,7α,25-triol + NADP+ + H2O ,
1.14.13.100: (25R)-cholest-5-ene-3β,26-diol + NADPH + H+ + oxygen → (25R)-cholest-5-ene-3β,7α,26-triol + NADP+ + H2O ,
1.14.13.126: calcitriol + NADPH + H+ + oxygen → calcitetrol + NADP+ + H2O ,
1.14.13.126: calcidiol + NADPH + H+ + oxygen → secalciferol + NADP+ + H2O ,
1.14.13.132: squalene + NADPH + oxygen + H+ → (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O ,
1.14.13.148: trimethylamine + NADPH + oxygen → trimethylamine N-oxide + NADP+ + H2O ,
1.14.13.159: vitamin D3 + NADPH + H+ + oxygen → calcidiol + NADP+ + H2O ,
1.14.13.-: (4S)-limonene + NADPH + oxygen + H+ → (-)-cis-carveol + NADP+ + H2O ,
1.14.13.-: 17-α-hydroxyprogesterone + NADPH + H+ + oxygen → 11-desoxycortisol + NADP+ + H2O ,
1.14.13.-: indole + NADH + oxygen + H+ → indoxyl + NAD+ + H2O ,
1.14.13.-: 3-decaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + NADP+ + H2O ,
1.14.13.-: oleate + NADPH + oxygen + H+ → 18-hydroxyoleate + NADP+ + H2O ,
1.14.13.-: 7-dehydrocholesterol + NADPH + H+ + oxygen → 7-ketocholesterol + NADP+ + H2O ,
1.14.13.-: 2-methoxy-6-(all-trans-decaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
1.14.13.-: progesterone + NADPH + H+ + oxygen → 11-deoxycorticosterone + NADP+ + H2O ,
1.14.14.1: melatonin + a reduced flavoprotein + oxygen → 6-hydroxymelatonin + an oxidized flavoprotein + H2O ,
1.14.14.1: acetone + a reduced flavoprotein + oxygen → acetol + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → trans-3'-hydroxycotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: 4-hydroxybenzaldehyde + a reduced flavoprotein + oxygen → protocatechualdehyde + an oxidized flavoprotein + H2O ,
1.14.14.1: (S)-nicotine + a reduced flavoprotein + oxygen → 2'-hydroxynicotine + an oxidized flavoprotein + H2O ,
1.14.14.1: bupropion + a reduced flavoprotein + oxygen → hydroxybupropion + an oxidized flavoprotein + H2O ,
1.14.14.1: melatonin + a reduced flavoprotein + oxygen → N-acetyl-serotonin + an oxidized flavoprotein + formaldehyde + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → 5'-hydroxycotinine + an oxidized flavoprotein + H2O ,
1.14.14.1: cotinine + a reduced flavoprotein + oxygen → N'-hydroxymethyl-norcotinine + an oxidized flavoprotein + H2O ,
1.14.14.-: N'-hydroxymethyl-norcotinine + a reduced flavoprotein + oxygen → norcotinine + an oxidized flavoprotein + H2O ,
1.14.15.4: 11-desoxycortisol + 2 a reduced adrenodoxin + oxygen + 2 H+ → cortisol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.4: 11-deoxycorticosterone + 2 a reduced adrenodoxin + oxygen + 2 H+ → corticosterone + 2 an oxidized adrenodoxin + H2O ,
1.14.15.5: 18-hydroxycorticosterone + 2 a reduced adrenodoxin + 2 H+ + oxygen → aldosterone + 2 an oxidized adrenodoxin + 2 H2O ,
1.14.15.5: corticosterone + 2 a reduced adrenodoxin + oxygen + 2 H+ → 18-hydroxycorticosterone + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: (20R,22R)-dihydroxycholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → pregnenolone + 4-methylpentanal + 2 an oxidized adrenodoxin + 2 H2O ,
1.14.15.6: (22R)-hydroxycholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → (20R,22R)-dihydroxycholesterol + 2 an oxidized adrenodoxin + H2O ,
1.14.15.6: cholesterol + 2 a reduced adrenodoxin + oxygen + 2 H+ → (22R)-hydroxycholesterol + 2 an oxidized adrenodoxin + H2O ,
1.14.16.1: tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.14.16.1: L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + oxygen = L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.14.16.2: tetrahydrobiopterin + L-tyrosine + oxygen → 4α-hydroxy-tetrahydrobiopterin + L-dopa ,
1.14.16.4: tetrahydrobiopterin + L-tryptophan + oxygen → 5-hydroxy-L-tryptophan + 4α-hydroxy-tetrahydrobiopterin ,
1.14.17.1: dopamine + L-ascorbate + H+ + oxygen → L-dehydro-ascorbate + (R)-noradrenaline + H2O ,
1.14.17.3: a C-terminal [protein]-glycine + L-ascorbate + oxygen → a C-terminal [protein]-hydroxyglycine + L-dehydro-ascorbate + H2O ,
1.14.18.1: L-tyrosine + oxygen → dopaquinone + H2O ,
1.14.19.3: α-linolenoyl-CoA + 2 a ferrocytochrome b5 + oxygen + 2 H+ → stearidonoyl-CoA + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.3: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 a ferrocytochrome b5 + oxygen + 2 H+ → (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.3: linoleoyl-CoA + an unknown reduced electron acceptor + oxygen → γ-linolenoyl-CoA + an unknown oxidized electron acceptor + 2 H2O ,
1.14.19.4: a [glycerolipid]-(11Z,14Z)-icosa-11,14-dienoate + 2 a ferrocytochrome b5 + oxygen + 2 H+ → a [glycerolipid]-di-homo-γ-linolenate + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.-: oleate + an unknown reduced electron acceptor + oxygen → linoleate + an unknown oxidized electron acceptor + 2 H2O ,
1.14.19.-: a dihydroceramide + 2 a ferrocytochrome b5 + oxygen + 2 H+ = a sphingosine ceramide + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.-: eicosatetraenoyl-CoA + 2 a ferrocytochrome b5 + oxygen + 2 H+ → (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.-: a [glycerolipid]-di-homo-γ-linolenate + 2 a ferrocytochrome b5 + oxygen + 2 H+ → a [glycerolipid]-arachidonate + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.-: dihomo γ-linolenoyl-CoA + 2 a ferrocytochrome b5 + oxygen + 2 H+ → arachidonyl-CoA + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.-: a D-glucosyl-N-acylsphinganine + 2 a ferrocytochrome b5 + oxygen + 2 H+ = a D-glucosyl-N-acylsphingosine + 2 a ferricytochrome b5 + 2 H2O ,
1.14.19.-: linoleate + an unknown reduced electron acceptor + oxygen → γ-linolenate + an unknown oxidized electron acceptor + 2 H2O ,
1.14.21.4: (R)-reticuline + NADPH + H+ + oxygen → salutaridine + NADP+ + 2 H2O ,
1.14.21.6: lathosterol + NAD(P)H + oxygen + H+ → 7-dehydrocholesterol + NAD(P)+ + 2 H2O ,
1.14.21.6: 5α-cholesta-7,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 7-dehydrodesmosterol + NAD(P)+ + 2 H2O ,
1.14.99.1: arachidonate + an unknown reduced electron acceptor + 2 oxygen → prostaglandin-H2 + an unknown oxidized electron acceptor + H2O ,
1.14.99.3: ferroheme b + 3 an unknown reduced electron acceptor + 3 oxygen + 2 H+ → carbon monoxide + Fe2+ + biliverdin-IX-α + 3 an unknown oxidized electron acceptor + 3 H2O ,
1.14.99.9: progesterone + NADPH + oxygen + H+ → 17-α-hydroxyprogesterone + NADP+ + H2O ,
1.14.99.9: a C21-steroid + an unknown reduced electron acceptor + oxygen → a 17α-hydroxy-C21-steroid + an unknown oxidized electron acceptor + H2O ,
1.14.99.9: pregnenolone + NADPH + H+ + oxygen → 17-α-hydroxypregnenolone + NADP+ + H2O ,
1.14.99.10: a C21-steroid + a reduced [NADPH-hemoprotein reductase] + oxygen → a 21-hydroxy-C21-steroid + an oxidized [NADPH-hemoprotein reductase] + H2O ,
1.14.99.36: all-trans-β-carotene + oxygen → 2 all-trans-retinal ,
1.14.99.38: cholesterol + an unknown reduced electron acceptor + oxygen → cholest-5-ene-3β,25-diol + an unknown oxidized electron acceptor + H2O ,
1.14.-.-: 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + an unknown reduced electron acceptor + oxygen → 3-demethylubiquinol-10 + an unknown oxidized electron acceptor + H2O ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.16.1.7: 2 an Fe(II)-siderophore + NAD+ + H+ ← 2 an Fe(III)-siderophore + NADH ,
1.16.3.1: 4 Fe2+ + 4 H+ + oxygen → 4 Fe3+ + 2 H2O ,
1.16.5.1: L-ascorbate[in] + Fe3+[out] ↔ monodehydroascorbate radical[in] + Fe2+[out] ,
1.16.5.1: L-ascorbate[in] + Fe3+[out] → monodehydroascorbate radical[in] + Fe2+[out] ,
1.17.1.4: hypoxanthine + NAD+ + H2O → xanthine + NADH + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.1.-: an all-trans retinol-[cellular-retinol-binding-protein] + NAD+ + H2O → all-trans-retinoate + NADH + H+ ,
1.17.3.2: xanthine + oxygen + H2O → hydrogen peroxide + urate ,
1.17.3.2: an organic molecule + H2O + 2 oxygen → an alcohol + 2 superoxide + 2 H+ ,
1.17.4.-: phylloquinone + oxidized dithiothreitol + H2O = dithiothreitol + vitamin K 2,3-epoxide ,
1.17.7.2: 71-hydroxychlorophyll a + 2 a reduced ferredoxin + 2 H+ = chlorophyll a + 2 an oxidized ferredoxin + H2O ,
1.17.99.3: (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an unknown oxidized electron acceptor + H2O = (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + an unknown reduced electron acceptor ,
1.17.99.-: (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + an unknown oxidized electron acceptor → (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + an unknown reduced electron acceptor ,
1.20.4.2: 2 glutathione + methylarsonate → glutathione disulfide + methylarsonite ,
1.21.1.-: 3,5-diiodo-L-tyrosine + 2 NADPH + H+ → L-tyrosine + 2 iodide + 2 NADP+ ,
1.97.1.10: 3,5,3'-triiodo-L-thyronine + iodide + an unknown oxidized electron acceptor + H+ ← L-thyroxine + an unknown reduced electron acceptor ,
1.97.1.10: 3,3',5'-triiodo-L-thyronine + an unknown reduced electron acceptor → 3,3'-diiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
1.97.1.10: 3',5'-diiodothyronine + an unknown reduced electron acceptor → 3'-monoiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
1.97.1.11: 3,5,3'-triiodo-L-thyronine + an unknown reduced electron acceptor → 3,3'-diiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
1.97.1.11: 3,5-diiodothyronine + an unknown reduced electron acceptor → 3-monoiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
1.97.1.11: 3,3',5'-triiodo-L-thyronine + iodide + an unknown oxidized electron acceptor + H+ ← L-thyroxine + an unknown reduced electron acceptor ,
1.-.-.-: an even numbered straight chain 2,3,4-saturated fatty acid + NAD(P)H + H+ + oxygen → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + NAD(P)+ + H2O ,
2.1.1.1: nicotinamide + S-adenosyl-L-methionine → 1-methylnicotinamide + S-adenosyl-L-homocysteine ,
2.1.1.2: guanidinoacetate + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + creatine + H+ ,
2.1.1.4: N-acetyl-serotonin + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + melatonin + H+ ,
2.1.1.5: L-homocysteine + glycine betaine → L-methionine + dimethylglycine ,
2.1.1.6: S-adenosyl-L-methionine + dopamine → S-adenosyl-L-homocysteine + 3-methoxytyramine + H+ ,
2.1.1.6: L-dopa + S-adenosyl-L-methionine → 3-O-methyldopa + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: 3,4-dihydroxyphenylacetate + S-adenosyl-L-methionine → homovanillate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: orcinol + S-adenosyl-L-methionine → 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: 3,4-dihydroxyphenylglycol + S-adenosyl-L-methionine → 3-methoxy-4-hydroxyphenylglycol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: 3,4-dihydroxymandelate + S-adenosyl-L-methionine → vanillyl mandelate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: a catechol + S-adenosyl-L-methionine → a guaiacol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: (R)-noradrenaline + S-adenosyl-L-methionine → normetanephrine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.6: (R)-adrenaline + S-adenosyl-L-methionine → metanephrine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.8: histamine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + Nτ-methylhistamine + H+ ,
2.1.1.10: S-methyl-L-methionine + L-homocysteine → 2 L-methionine + H+ ,
2.1.1.13: L-homocysteine + an N5-methyl-tetrahydrofolate → L-methionine + a tetrahydrofolate ,
2.1.1.17: an L-1-phosphatidylethanolamine + S-adenosyl-L-methionine → a phosphatidyl-N-methylethanolamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.20: S-adenosyl-L-methionine + glycine → S-adenosyl-L-homocysteine + sarcosine + H+ ,
2.1.1.28: phenylethanolamine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + N-methylphenylethanolamine + H+ ,
2.1.1.28: S-adenosyl-L-methionine + (R)-noradrenaline → S-adenosyl-L-homocysteine + (R)-adrenaline + H+ ,
2.1.1.43: a [histone]-L-lysine + S-adenosyl-L-methionine → a [histone] N6-methyl-L-lysine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.45: a 5,10-methylene-tetrahydrofolate + dUMP → dTMP + a 7,8-dihydrofolate ,
2.1.1.49: an amine + S-adenosyl-L-methionine → a methylated amine + S-adenosyl-L-homocysteine ,
2.1.1.49: (S)-nicotine + S-adenosyl-L-methionine → nicotine isomethonium ion + S-adenosyl-L-homocysteine ,
2.1.1.62: m7G(5')pppAm + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + m7G(5')pppm6Am + H+ ,
2.1.1.64: 3-demethylubiquinol-10 + S-adenosyl-L-methionine → ubiquinol-10 + S-adenosyl-L-homocysteine + H+ ,
2.1.1.67: a thiopurine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + a thiopurine S-methylether + H+ ,
2.1.1.77: S-adenosyl-L-methionine + a [protein]-L-β-isoaspartate → S-adenosyl-L-homocysteine + a protein L-β-isoaspartate α-methyl ester ,
2.1.1.100: a [protein] c-terminal S-farnesyl-L-cysteine + S-adenosyl-L-methionine → a [protein] c-terminal S-farnesyl-L-cysteine methyl ester + S-adenosyl-L-homocysteine ,
2.1.1.114: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine → 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.114: 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H+ ,
2.1.1.114: 3,4-dihydroxy-5-all-trans-nonaprenylbenzoate + S-adenosyl-L-methionine → 3-methoxy-4-hydroxy-5-all-trans-nonaprenylbenzoate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.125: S-adenosyl-L-methionine + [histone]-L-arginine → S-adenosyl-L-homocysteine + [histone]-Nω-methyl-arginine + 2 H+ ,
2.1.1.126: S-adenosyl-L-methionine + [myelin basic protein]-L-arginine → S-adenosyl-L-homocysteine + [myelin basic protein]-Nω-methyl-arginine + H+ ,
2.1.1.137: S-adenosyl-L-methionine + methylarsonite → S-adenosyl-L-homocysteine + cacodylate + 2 H+ ,
2.1.1.137: arsenite + S-adenosyl-L-methionine → methylarsonate + S-adenosyl-L-homocysteine + H+ ,
2.1.1.201: 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine → 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-nonaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-nonaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-heptaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-heptaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-decaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: a 3-(all-trans-polyrenyl)benzene-1,2-diol + S-adenosyl-L-methionine → a 2-methoxy-6-(all-trans-polyprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.233: S-adenosyl-L-methionine + a [phosphatase 2A protein] C-terminal L-leucine → S-adenosyl-L-homocysteine + a [phosphatase 2A protein] C-terminal L-leucine methyl ester ,
2.1.1.244: 2 S-adenosyl-L-methionine + an N-terminal-PPK-[protein] → 2 S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-PPK-[protein] + 2 H+ ,
2.1.1.244: 3 S-adenosyl-L-methionine + an N-terminal-(A/S)PK-[protein] → 3 S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein] + 3 H+ ,
2.1.1.282: S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPheS-adenosyl-L-homocysteine + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + H+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl donor → S-adenosyl-L-homocysteine + a methylated methyl donor + H+ ,
2.1.2.1: L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H2O ,
2.1.2.2: an N10-formyl-tetrahydrofolate + N1-(5-phospho-β-D-ribosyl)glycinamide → a tetrahydrofolate + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + H+ ,
2.1.2.3: an N10-formyl-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide → a tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
2.1.2.5: a 5-formiminotetrahydrofolate + L-glutamate ← N-formimino-L-glutamate + a tetrahydrofolate ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate → L-citrulline + phosphate + H+ ,
2.1.4.1: glycine + L-arginine → guanidinoacetate + L-ornithine ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ← D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate → β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate → β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.3.1.1: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.4: D-glucosamine 6-phosphate + acetyl-CoA → N-acetyl-D-glucosamine 6-phosphate + coenzyme A + H+ ,
2.3.1.5: an arylamine + acetyl-CoA = an N-acetylarylamine + coenzyme A ,
2.3.1.6: choline + acetyl-CoA = acetylcholine + coenzyme A ,
2.3.1.7: L-carnitine + acetyl-CoA ← O-acetylcarnitine + coenzyme A ,
2.3.1.9: acetyl-CoA + propanoyl-CoA = β-ketovaleryl-CoA + coenzyme A ,
2.3.1.9: 2-methylacetoacetyl-CoA + coenzyme A ↔ propanoyl-CoA + acetyl-CoA ,
2.3.1.9: 2 acetyl-CoA ↔ acetoacetyl-CoA + coenzyme A ,
2.3.1.12: acetyl-CoA + dihydrolipoamide = S-acetyldihydrolipoamide + coenzyme A ,
2.3.1.13: glycine + an acyl-CoA = an N-acylglycine + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.16: docosahexaenoyl-CoA + acetyl-CoA ← 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + coenzyme A ,
2.3.1.16: acetyl-CoA + butanoyl-CoA = 3-oxohexanoyl-CoA + coenzyme A ,
2.3.1.16: OPC4-CoA + acetyl-CoA = OPC6-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: 4-hydroxybenzoyl-CoA + acetyl-CoA = 4-hydroxybenzoyl-acetyl-CoA + coenzyme A ,
2.3.1.16: a 2,3,4-saturated fatty acyl CoA + acetyl-CoA ← a 3-oxoacyl-CoA + coenzyme A ,
2.3.1.16: 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + acetyl-CoA = 3,22-dioxochol-4-en-24-oyl-CoA + coenzyme A ,
2.3.1.16: OPC6-CoA + acetyl-CoA = OPC8-3-ketoacyl-CoA + coenzyme A ,
2.3.1.16: acetyl-CoA + octanoyl-CoA = 3-oxodecanoyl-CoA + coenzyme A ,
2.3.1.16: jasmonoyl-CoA + acetyl-CoA = OPC4-3-ketoacyl-CoA + coenzyme A ,
2.3.1.20: a 1,2-diacyl-sn-glycerol + an acyl-CoA → a triacyl-sn-glycerol + coenzyme A ,
2.3.1.21: a long-chain acyl-CoA + L-carnitine ↔ an O-acyl-L-carnitine + coenzyme A ,
2.3.1.21: L-carnitine + palmitoyl-CoA = L-palmitoylcarnitine + coenzyme A ,
2.3.1.22: a 2-monoglyceride + an acyl-CoA = a 1,2-diacyl-sn-glycerol + coenzyme A ,
2.3.1.23: an acyl-CoA + a 1-acyl 2-lyso-phosphatidylcholine ↔ a phosphatidylcholine + coenzyme A ,
2.3.1.24: an acyl-CoA + a sphingoid base = a ceramide + coenzyme A + H+ ,
2.3.1.24: phytosphingosine + a very long chain fatty acyl-CoA = a phytoceramide + coenzyme A + H+ ,
2.3.1.26: cholesterol + an acyl-CoA = a cholesterol ester + coenzyme A ,
2.3.1.29: glycine + acetyl-CoA = 2-amino-3-oxobutanoate + coenzyme A + H+ ,
2.3.1.37: glycine + succinyl-CoA + H+ → CO2 + 5-aminolevulinate + coenzyme A ,
2.3.1.42: a long-chain acyl-CoA + dihydroxyacetone phosphate = an acylglycerone phosphate + coenzyme A ,
2.3.1.43: a sterol + a phosphatidylcholine = a 1-acyl 2-lyso-phosphatidylcholine + a steryl-ester ,
2.3.1.50: L-serine + palmitoyl-CoA + H+ → CO2 + 3-dehydrosphinganine + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.57: spermine + acetyl-CoA → N1-acetylspermine + coenzyme A + H+ ,
2.3.1.57: acetyl-CoA + spermidine → N1-acetylspermidine + coenzyme A + H+ ,
2.3.1.57: putrescine + acetyl-CoA → N-acetylputrescine + coenzyme A + H+ ,
2.3.1.57: an aliphatic α,ω-diamine + acetyl-CoA = an aliphatic N-acetyl-diamine + coenzyme A + H+ ,
2.3.1.65: chenodeoxycholoyl-CoA + taurine → taurochenodeoxycholate + coenzyme A + H+ ,
2.3.1.65: glycine + choloyl-CoA → glycocholate + coenzyme A + H+ ,
2.3.1.65: choloyl-CoA + taurine → taurocholate + coenzyme A + H+ ,
2.3.1.65: chenodeoxycholoyl-CoA + glycine → glycochenodeoxycholate + coenzyme A + H+ ,
2.3.1.67: acetyl-CoA + a 1-alkyl-2-lyso-sn-glycero-3-phosphocholine = a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + coenzyme A ,
2.3.1.75: a long-chain acyl-CoA + a long-chain alcohol = a long-chain ester + coenzyme A ,
2.3.1.75: arachidoyl-CoA + 1-dodecanol = arachidoyl dodecanoate + coenzyme A ,
2.3.1.75: a long-chain acyl-CoA + ethanol → a fatty acid-ethyl ester + coenzyme A ,
2.3.1.75: a very long chain alcohol + a long-chain acyl-CoA = a wax ester + coenzyme A ,
2.3.1.78: α-D-glucosaminide-[heparan sulfate] + acetyl-CoA = N-acetyl-α-D-glucosaminide-[heparan sulfate] + coenzyme A ,
2.3.1.80: an L-cysteine-S-conjugate + acetyl-CoA → a mercapturate + coenzyme A + H+ ,
2.3.1.80: 4-hydroxy-2-nonenal-[L-Cys] conjugate + acetyl-CoA → 4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ ,
2.3.1.85: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = a long-chain fatty acid + n CO2 + (n+1) coenzyme A + 2n NADP+ ,
2.3.1.87: acetyl-CoA + a 2-arylethylamine = an N-acetyl-2-arylethylamine + coenzyme A + H+ ,
2.3.1.87: acetyl-CoA + serotonin → N-acetyl-serotonin + coenzyme A + H+ ,
2.3.1.97: glycyl-peptide + myristoyl-CoA = N-tetradecanoylglycyl-peptide + coenzyme A ,
2.3.1.108: an [α-tubuline]-L-lysine + acetyl-CoA = an [α-tubulin]-N6-acetyl-L-lysine + coenzyme A + H+ ,
2.3.1.111: an acyl-CoA + n (R)-methylmalonyl-CoA + 2n NADPH + 2n H+ = a multi-methyl-branched acyl-CoA + n CO2 + n coenzyme A + 2n NADP+ ,
2.3.1.118: an N-hydroxy-arylamine + acetyl-CoA = an N-acetoxyarylamine + coenzyme A ,
2.3.1.135: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine → a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 2-acyl 1-lyso-phosphatidylcholine ,
2.3.1.135: an all-trans retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine → a cellular-retinol-binding protein + an all-trans-retinyl ester + a 2-acyl 1-lyso-phosphatidylcholine ,
2.3.1.137: octanoyl-CoA + L-carnitine = L-octanoylcarnitine + coenzyme A ,
2.3.1.150: salutaridinol + acetyl-CoA → 7-O-acetylsalutaridinol + coenzyme A ,
2.3.1.154: propanoyl-CoA + 4,8,12-trimethyltridecanoyl-CoA = 3-oxopristanoyl-CoA + coenzyme A ,
2.3.1.158: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol → a triacyl-sn-glycerol + a 1-acyl 2-lyso-phosphatidylcholine ,
2.3.1.176: 3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + coenzyme A → chenodeoxycholoyl-CoA + propanoyl-CoA ,
2.3.1.176: 3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + coenzyme A → choloyl-CoA + propanoyl-CoA ,
2.3.1.199: malonyl-CoA + linoleoyl-CoA + H+ → 3-oxo-(11Z,14Z)-icosa-11,14-dienoyl-CoA + CO2 + coenzyme A ,
2.3.1.223: 2,3-didehydroadipyl-CoA + acetyl-CoA = 3-oxo-5,6-didehydrosuberyl-CoA + coenzyme A ,
2.3.1.231: 7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + CO2 + S-adenosyl-L-methionine → wybutosine37 in tRNAPhe + S-adenosyl-L-homocysteine + 2 H+ ,
2.3.1.-: malonyl-CoA + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + H+ → 3-oxo-docosapentaenoyl-CoA + CO2 + coenzyme A ,
2.3.1.-: docosahexaenoyl-CoA + a glycerolipid ↔ a [glycerolipid]-docosahexaenoate + coenzyme A ,
2.3.1.-: palmitoyl-CoA + malonyl-CoA + H+ → 3-oxo-stearoyl-CoA + CO2 + coenzyme A ,
2.3.1.-: malonyl-CoA + γ-linolenoyl-CoA + H+ → 3-oxo-dihomo γ-linolenoyl-CoA + CO2 + coenzyme A ,
2.3.1.-: (11Z,14Z)-icosa-11,14-dienoyl-CoA + a glycerolipid → a [glycerolipid]-(11Z,14Z)-icosa-11,14-dienoate + coenzyme A ,
2.3.1.-: malonyl-CoA + stearidonoyl-CoA + H+ → 3-oxo-icosatetraenoyl-CoA + CO2 + coenzyme A ,
2.3.1.-: 2 a 1,2-diacyl-sn-glycerol ↔ a triacyl-sn-glycerol + a 2-monoglyceride ,
2.3.1.-: malonyl-CoA + docosapentaenoyl-CoA + H+ → 3-oxo-tetracosapentaenoyl-CoA + CO2 + coenzyme A ,
2.3.2.2: glutathione + a standard α amino acid → L-cysteinyl-glycine + an (γ-L-glutamyl)-L-amino acid ,
2.3.2.2: hypoglycin A + glutathione = hypoglycin B + L-cysteinyl-glycine ,
2.3.2.4: an (γ-L-glutamyl)-L-amino acid → an L-amino acid + 5-oxoproline ,
2.3.2.-: an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + an [(E3-independent) E2 ubiquitin-conjugating enzyme]-L-cysteine → an [E1 ubiquitin-activating enzyme]-L-cysteine + an S-ubiquitinyl-[(E3-independent) E2 ubiquitin-conjugating enzyme]-L-cysteine ,
2.3.2.-: an S-ubiquitinyl-[HECT-type E3 ubiquitin transferase]-L-cysteine + a [protein]-L-lysine → a [HECT-type E3 ubiquitin transferase]-L-cysteine + an N6-monoubiquitinyl-[protein]-L-lysine + H+ ,
2.3.2.-: an S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + a [protein]-L-lysine → an [E2 ubiquitin-conjugating enzyme]-L-cysteine + an N6-monoubiquitinyl-[protein]-L-lysine + H+ ,
2.3.2.-: an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + an [E2 ubiquitin-conjugating enzyme]-L-cysteine → an [E1 ubiquitin-activating enzyme]-L-cysteine + an S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine ,
2.3.2.-: an S-ubiquitinyl-[(E3-independent) E2 ubiquitin-conjugating enzyme]-L-cysteine + a [protein]-L-lysine → an N6-monoubiquitinyl-[protein]-L-lysine + an [(E3-independent) E2 ubiquitin-conjugating enzyme]-L-cysteine + H+ ,
2.3.2.-: an S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + a [HECT-type E3 ubiquitin transferase]-L-cysteine → an [E2 ubiquitin-conjugating enzyme]-L-cysteine + an S-ubiquitinyl-[HECT-type E3 ubiquitin transferase]-L-cysteine ,
2.3.3.8: oxaloacetate + acetyl-CoA + ADP + phosphate ← citrate + ATP + coenzyme A ,
2.3.3.10: acetoacetyl-CoA + acetyl-CoA + H2O → (S)-3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ ,
2.3.3.16: oxaloacetate[mitochondrial lumen] + acetyl-CoA[mitochondrial lumen] + H2O[mitochondrial lumen] → citrate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + H+[mitochondrial lumen] ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate = α-D-glucose 1-phosphate + (1,4-α-D-glucosyl)(n-1) ,
2.4.1.1: a glycogen + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: a maltodextrin(n) + phosphate = a maltodextrin(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a debranched limit dextrin + n phosphate → n α-D-glucose 1-phosphate ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.11: UDP-α-D-glucose + (1,4-α-D-glucosyl)(n) glycogenin → (1,4-α-D-glucosyl)(n+1) glycogenin + UDP ,
2.4.1.17: oleanolate + UDP-α-D-glucuronate = oleanolate 3 β-D-glucuronoside + UDP + H+ ,
2.4.1.17: 3,5,3'-triiodo-L-thyronine + UDP-α-D-glucuronate → 3,5,3'-triiodo-L-thyronine acyl β-D-glucuronide + UDP + H+ ,
2.4.1.17: mycophenolate + UDP-α-D-glucuronate = mycophenolic acid O-acyl-glucuronide + UDP ,
2.4.1.17: trans-3'-hydroxycotinine + UDP-α-D-glucuronate → trans-3-hydroxycotinine-glucuronide + UDP + H+ ,
2.4.1.17: 3,3',5-triiodothyroacetate + UDP-α-D-glucuronate → triiodothyroacetate ester glucuronide + UDP ,
2.4.1.17: cotinine + UDP-α-D-glucuronate → cotinine-glucuronide + UDP ,
2.4.1.17: L-thyroxine + UDP-α-D-glucuronate → L-thyroxine acyl β-D-glucuronide + UDP + H+ ,
2.4.1.17: a non-glucuronosylated glucuronoside acceptor + UDP-α-D-glucuronate = a glucuronosylated glucuronoside acceptor + UDP ,
2.4.1.17: tetraiodothyroacetate + UDP-α-D-glucuronate → tetraiodothyroacetate ester glucuronide + UDP ,
2.4.1.17: (S)-nicotine + UDP-α-D-glucuronate → nicotine-glucuronide + UDP ,
2.4.1.17: 3,5,3'-triiodo-L-thyronine + UDP-α-D-glucuronate → 3,5,3'-triiodo-L-thyronine phenolic β-D-glucuronide + UDP + H+ ,
2.4.1.17: mycophenolate + UDP-α-D-glucuronate = mycophenolic acid phenolic glucuronide + UDP + H+ ,
2.4.1.17: tetraiodothyroacetate + UDP-α-D-glucuronate → tetraiodothyroacetate ether glucuronide + UDP + H+ ,
2.4.1.17: N-acetyl-serotonin + UDP-α-D-glucuronate → N-acetyl-serotonin glucuronide + UDP ,
2.4.1.17: 3,3',5-triiodothyroacetate + UDP-α-D-glucuronate → triiodothyroacetate ether glucuronide + UDP + H+ ,
2.4.1.17: L-thyroxine + UDP-α-D-glucuronate → L-thyroxine phenolic β-D-glucuronide + UDP + H+ ,
2.4.1.17: 5-hydroxytryptophol + UDP-α-D-glucuronate → 5-hydroxytryptophol glucuronide + UDP ,
2.4.1.18: n a 1,4-α-D-glucan = n starch + n H2O ,
2.4.1.18: a 1,4-α-D-glucan = a glycogen ,
2.4.1.18: a glucosylated glycogenin → a glycogen ,
2.4.1.22: UDP-α-D-galactose + β-D-glucose = α-lactose + UDP + H+ ,
2.4.1.25: a limit dextrin → a limit dextrin with short branches ,
2.4.1.37: UDP-α-D-galactose + a glycoprotein-α-L-fucosyl-(1,2)-D-galactose = UDP + a galactosyl-(1->3)-[α-L-fucosyl(1->2)]-D-galactosyl-R + H+ ,
2.4.1.38: UDP-α-D-galactose + N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-R → i antigen + UDP + H+ ,
2.4.1.38: UDP-α-D-galactose + an N-acetyl-β-D-glucosaminyl-R → β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.38: UDP-α-D-galactose + N-acetyl-β-D-galactosyl-(1,4)-[N-acetyl-β-D-glucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-R → I antigen + UDP + H+ ,
2.4.1.40: UDP-N-acetyl-D-galactosamine + a glycoprotein-α-L-fucosyl-(1,2)-D-galactose = glycoprotein N-acetyl-α-D-galactosaminyl-(1,3)-[α-L-fucosyl-(1,2)]-D-galactose + UDP + H+ ,
2.4.1.41: UDP-N-acetyl-α-D-galactosamine + a [glycoprotein]-(L-serine/L-threonine) → N-acetyl-α-D-galactosalaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.45: UDP-α-D-galactose + a 2-(2-hydroxyacyl)sphingosine = a 1-(β-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP + H+ ,
2.4.1.50: UDP-α-D-galactose + a [procollagen]-5-hydroxy-L-lysine = a procollagen 5-(galactosyloxy)-L-lysine + UDP + H+ ,
2.4.1.62: UDP-α-D-galactose + gangloside GM2 = ganglioside GM1a + UDP + H+ ,
2.4.1.65: GDP-L-fucose + 1,3-β-D-galactosyl-N-acetyl-D-glucosaminyl-R = 1,3-β-D-galactosyl-(α-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl- R + GDP + H+ ,
2.4.1.68: GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine = GDP + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-[α-L-fucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl}asparagine + H+ ,
2.4.1.69: GDP-L-fucose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide = III2-α-fucosyllactotetraosylceramide + GDP + H+ ,
2.4.1.79: UDP-N-acetyl-α-D-galactosamine + an α-D-galactosyl-(1->4)-β-D-galactosyl-(1->4)-β-D-glucosylceramide = an N-acetyl-β-D-galactosaminyl-(1,3)-α-D-galactosyl-(1,4)-β-D-galactosyl-(1,4)-β-D-glucosylceramide + UDP + H+ ,
2.4.1.80: UDP-α-D-glucose + a dihydroceramide = a D-glucosyl-N-acylsphinganine + UDP + H+ ,
2.4.1.80: UDP-α-D-glucose + a sphingosine ceramide + H+ = a D-glucosyl-N-acylsphinganine + UDP ,
2.4.1.83: a dolichyl phosphate + GDP-α-D-mannose → a dolichyl β-D-mannosyl phosphate + GDP ,
2.4.1.87: UDP-α-D-galactose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-D-galactosyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R + UDP + H+ ,
2.4.1.90: UDP-α-D-galactose + N-acetyl-β-D-glucosamine = β-D-galactosyl-1,4-N-acetyl-β-D-glucosamine + UDP + H+ ,
2.4.1.92: UDP-N-acetyl-α-D-galactosamine + a 1-O-[O-(N-acetyl-α-neuraminyl)-2,3-β-D-galactosyl-1,4-β-D-glucosyl]ceramide = gangloside GM2 + UDP + H+ ,
2.4.1.101: UDP-N-acetyl-α-D-glucosamine + a (mannosyl)5-N-glycan = a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan + UDP + H+ ,
2.4.1.102: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine → β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.117: UDP-α-D-glucose + a dolichyl phosphate → a dolichyl β-D-glucosyl phosphate + UDP ,
2.4.1.122: UDP-α-D-galactose + N-acetyl-α-D-galactosalaminyl-[glycoprotein] → β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + UDP + H+ ,
2.4.1.131: a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol + 2 GDP-α-D-mannose → a (mannosyl)5-(N-acetylglucosaminyl)2-diphosphodolichol + 2 GDP + 2 H+ ,
2.4.1.132: a mannosyl-(N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.133: UDP-α-D-galactose + O-β-D-xylosyl-[core protein] → β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.141: an N-acetylglucosaminyl-diphosphodolichol + UDP-N-acetyl-α-D-glucosamine → an (N-acetylglucosaminyl)2-diphosphodolichol + UDP + H+ ,
2.4.1.142: an (N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a mannosyl-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.143: α-D-mannosyl-1,6-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3)-β-D-mannosyl-[glycoprotein] + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3)-β-D-mannosyl-[glycoprotein] + UDP + H+ ,
2.4.1.144: N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,3-(N-acetyl-β-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-(N-acetyl-β-D-glucosaminyl-1,4)-β-D-mannosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.145: (N-acetyl-β-D-glucosaminyl-1,2)-α-D-mannosyl-1,3-(β-N-acetyl-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-R + UDP-N-acetyl-α-D-glucosamine = N-acetyl-β-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-α-D-mannosyl-1,3-(β-N-acetyl-D-glucosaminyl-1,2-α-D-mannosyl-1,6)-β-D-mannosyl-R + UDP + H+ ,
2.4.1.146: β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP-N-acetyl-α-D-glucosamine → N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→6)]-N-acetyl-α-D-galactosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.149: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.150: UDP-N-acetyl-α-D-glucosamine + i antigen → N-acetyl-β-D-galactosyl-(1,4)-[N-acetyl-β-D-glucosyl-(1,6)]-N-acetyl-β-D-glucosaminyl-(1,3)-β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.150: UDP-N-acetyl-α-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → N-acetyl-β-D-glucosaminyl-(1→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + UDP + H+ ,
2.4.1.152: GDP-L-fucose + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → Lewis x epitope + GDP + H+ ,
2.4.1.155: [(2,4),(2)]-N-linked glycan + UDP-N-acetyl-α-D-glucosamine = [(2,4),(2,6)]-N-linked glycan + UDP + H+ ,
2.4.1.174: UDP-N-acetyl-D-galactosamine + D-glucuronosyl-1,3-β-D-galactosyl-[proteoglycan] → N-acetyl-D-galactosaminyl-1,4-β-D-glucuronyl-1,3-β-D-galactosyl-[proteoglycan] + UDP + H+ ,
2.4.1.174: UDP-N-acetyl-D-galactosamine + β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] = N-acetyl-D-galactosaminyl-(1→4)-β-D-glucuronyl-(1→3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.175: UDP-N-acetyl-α-D-galactosamine + β-D-glucuronosyl-[chondroitin/dermatan] → N-acetyl-β-D-galactosaminide-[chondroitin/dermatan] + UDP + H+ ,
2.4.1.198: an L-1-phosphatidyl-inositol + UDP-N-acetyl-α-D-glucosamine = a 6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + UDP + H+ ,
2.4.1.212: N-acetyl-α-D-glucosaminide-[hyaluronan] + UDP-α-D-glucuronate = β-D-glucuronosyl-[hyaluronan] + UDP ,
2.4.1.212: UDP-N-acetyl-α-D-glucosamine + β-D-glucuronosyl-[hyaluronan] = N-acetyl-α-D-glucosaminide-[hyaluronan] + UDP ,
2.4.1.214: GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine = N(4)-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-[α-L-fucosyl-(1,3)]-N-acetyl-β-D-glucosaminyl}asparagine + GDP + H+ ,
2.4.1.221: GDP-β-L-fucose + a [protein]-L-serine = GDP + a [protein]-3-O-L-fucosyl-L-serine + H+ ,
2.4.1.222: UDP-N-acetyl-α-D-glucosamine + a fucosyl-protein = UDP + O-β-D-GlcNAc-fucosyl-protein ,
2.4.1.223: β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP-N-acetyl-α-D-glucosamine → α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucuronosyl-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein] + UDP + H+ ,
2.4.1.224: β-D-glucuronosyl-[heparan sulfate] + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-glucosaminide-[heparan sulfate] + UDP + H+ ,
2.4.1.225: N-acetyl-α-D-glucosaminide-[heparan sulfate] + UDP-α-D-glucuronate → β-D-glucuronosyl-[heparan sulfate] + UDP ,
2.4.1.226: N-acetyl-β-D-galactosaminide-[chondroitin/dermatan] + UDP-α-D-glucuronate → β-D-glucuronosyl-[chondroitin/dermatan] + UDP ,
2.4.1.228: UDP-α-D-galactose + a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide = an α-D-galactosyl-(1->4)-β-D-galactosyl-(1->4)-β-D-glucosylceramide + UDP + H+ ,
2.4.1.244: UDP-N-acetyl-α-D-galactosamine + an N-acetyl-β-D-glucosaminyl-R = N-acetyl-β-D-galactosaminyl-(1->4)-N-acetyl-β-D-glucosaminyl-[glycoprotein] + UDP + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [protein]-L-serine = UDP + an N-acetyl-α-D-glucosaminyl-L-serine-[glycoprotein] + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) → UDP + an N-acetyl-α-D-glucosaminyl-[glycoprotein] + H+ ,
2.4.1.255: UDP-N-acetyl-α-D-glucosamine + a [protein]-L-threonine = UDP + an N-acetyl-α-D-glucosaminyl-L-threonine-[glycoprotein] + H+ ,
2.4.1.256: a (glucosyl)2(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → dolichyl diphosphooligosaccharide + a dolichyl phosphate + H+ ,
2.4.1.257: a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol + GDP-α-D-mannose → a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol + GDP + H+ ,
2.4.1.258: a (mannosyl)5-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.259: a (mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.260: a (mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.261: a (mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-mannosyl phosphate → a (mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.265: a glucosyl-(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → a (glucosyl)2(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.267: a (mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl β-D-glucosyl phosphate → a glucosyl-(mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + a dolichyl phosphate + H+ ,
2.4.1.274: UDP-α-D-galactose + a D-glucosyl-N-acylsphingosine = a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.1.275: an N-acetyl-β-D-glucosaminyl-(1-3)-β-D-galactosyl-(1-4)-β-D-glucosyl-(1↔1)-ceramide + UDP-α-D-galactose = a β-D-galactosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1-3)-β-D-galactosyl-1,4-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.1.-: an N-acetyl-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide + UDP-α-D-galactose = β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + UDP + H+ ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: a purine ribonucleoside + arsenate → ribose-1-arsenate + a purine base ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine ,
2.4.2.1: xanthosine + phosphate → α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine ,
2.4.2.1: a purine ribonucleoside + phosphate = α-D-ribose-1-phosphate + a purine base ,
2.4.2.2/2.4.2.3: uridine + phosphate ↔ α-D-ribose-1-phosphate + uracil ,
2.4.2.2/2.4.2.4: thymidine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + thymine ,
2.4.2.3: 2'-deoxyuridine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + uracil ,
2.4.2.7: AMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + adenine ,
2.4.2.8: IMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + hypoxanthine ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.9: UMP + diphosphate = 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.12: β-nicotinamide D-ribonucleotide + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + nicotinamide + H+ ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.26: a core protein L-serine + UDP-α-D-xylose → O-β-D-xylosyl-[core protein] + UDP ,
2.4.2.28: S-methyl-5'-thioadenosine + phosphate → S-methyl-5-thio-α-D-ribose 1-phosphate + adenine ,
2.4.2.31: a [protein]-L-arginine + NAD+ = a protein-Nω-(ADP-D-ribosyl)-L-arginine + nicotinamide + H+ ,
2.4.2.36: a diphthamide-[translation elongation factor 2] + NAD+ = N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide ,
2.4.99.1: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-N-acetylneuraminyl-2,6-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + CMP + H+ ,
2.4.99.4: β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + CMP-N-acetyl-β-neuraminate → α-N-acetylneuraminyl-2,3-β-D-galactosyl-1,3-N-acetyl-α-D-galactosaminyl-[glycoprotein] + CMP + H+ ,
2.4.99.6: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R → α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-R + CMP + H+ ,
2.4.99.7: α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-[(α-N-acetylneuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP + H+ ,
2.4.99.8: α-N-acetylneuraminyl-2,3-β-D-galactosyl-R + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-2,8-α-N-acetylneuraminyl-2,3-β-D-galactosyl-R + CMP ,
2.4.99.9: a β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP-N-acetyl-β-neuraminate = a 1-O-[O-(N-acetyl-α-neuraminyl)-2,3-β-D-galactosyl-1,4-β-D-glucosyl]ceramide + CMP ,
2.4.99.10: β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP-N-acetyl-β-neuraminate = α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosylceramide + CMP + H+ ,
2.4.99.20: nicotinate + NADP+ = nicotinate-adenine dinucleotide phosphate + nicotinamide ,
2.4.99.-: β-D-galactosyl-(1->3)-N-acetyl-β-D-glucosaminyl-R[Golgi lumen] + CMP-N-acetyl-β-neuraminate[Golgi lumen] = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R[Golgi lumen] + CMP[Golgi lumen] + H+[Golgi lumen] ,
2.4.99.-: CMP-N-acetyl-β-neuraminate + β-D-galactosyl-(1->3)-N-acetyl-α-D-galactosaminyl-R = α-N-acetylneuraminyl-(2->3)-β-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP + H+ ,
2.5.1.1: dimethylallyl diphosphate + isopentenyl diphosphate → geranyl diphosphate + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.10: geranyl diphosphate + isopentenyl diphosphate → (2E,6E)-farnesyl diphosphate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.17: ATP + cob(I)alamin = coenzyme B12 + PPPi ,
2.5.1.17: cob(I)yrinate a,c-diamide + ATP = adenosyl-cobyrinate a,c-diamide + PPPi ,
2.5.1.17: cobinamide + ATP = adenosylcobinamide + PPPi ,
2.5.1.18: 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H+ ,
2.5.1.18: glutathione + RX → a glutathione-toxin conjugate + HX ,
2.5.1.18: glutathione + 4-hydroxy-2-nonenal → 4-hydroxy-2-nonenal-glutathione conjugate ,
2.5.1.21: 2 (2E,6E)-farnesyl diphosphate + NAD(P)H + H+ → squalene + NAD(P)+ + 2 diphosphate ,
2.5.1.22: spermidine + S-adenosyl 3-(methylthio)propylamine → spermine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.26: an acylglycerone phosphate + a long-chain alcohol = a 1-alkyl-glycerone 3-phosphate + a long-chain carboxylate ,
2.5.1.29: isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate → geranylgeranyl diphosphate + diphosphate ,
2.5.1.32: 2 2-cis,6-trans,10-trans-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate ,
2.5.1.39: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate → 3-decaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.56: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = N-acetyl-β-neuraminate + phosphate ,
2.5.1.57: N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O → N-acetyl-β-neuraminate 9-phosphate + phosphate ,
2.5.1.58: a [protein]-L-cysteine + (2E,6E)-farnesyl diphosphate = a [protein]-S-farnesyl-L-cysteine + diphosphate ,
2.5.1.60: geranylgeranyl diphosphate + a [protein]-L-cysteine = a [protein]-S-geranylgeranyl-L-cysteine + diphosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.87: (2E,6E)-farnesyl diphosphate + 13 isopentenyl diphosphate → di-trans, poly-cis-polyprenyl diphosphate (C80) + 13 diphosphate ,
2.5.1.91: (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate → all-trans-decaprenyl diphosphate + 7 diphosphate ,
2.5.1.99: 2 geranylgeranyl diphosphate = all-trans-phytoene + 2 diphosphate ,
2.5.1.103: 2 (2E,6E)-farnesyl diphosphate = presqualene diphosphate + diphosphate ,
2.5.1.108: an L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H+ ,
2.5.1.114: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPheS-methyl-5'-thioadenosine + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe + H+ ,
2.5.1.-: heme b + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ oxaloacetate + L-glutamate ,
2.6.1.1: L-aspartate[mitochondrial lumen] + 2-oxoglutarate[mitochondrial lumen] = L-glutamate[mitochondrial lumen] + oxaloacetate[mitochondrial lumen] ,
2.6.1.2: 2-oxoglutarate + L-alanine → L-glutamate + pyruvate ,
2.6.1.3: 2-oxoglutarate + L-cysteine → L-glutamate + 3-mercaptopyruvate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate → 4-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.7: 3-hydroxy-L-kynurenine + 2-oxoglutarate ↔ 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate ,
2.6.1.7: L-kynurenine + 2-oxoglutarate ↔ L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate ,
2.6.1.13: L-ornithine + 2-oxoglutarate ↔ L-glutamate + L-glutamate-5-semialdehyde ,
2.6.1.13: L-ornithine + a 2-oxo carboxylate = a standard α amino acid + L-glutamate-5-semialdehyde ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.19: 2-oxoglutarate + β-alanine ↔ L-glutamate + malonate semialdehyde ,
2.6.1.19: 2-oxoglutarate + 4-aminobutanoate → L-glutamate + succinate semialdehyde ,
2.6.1.22: 2-oxoglutarate + (S)-3-amino-2-methylpropanoate ↔ L-glutamate + (S)-methylmalonate-semialdehyde ,
2.6.1.23: 2-oxoglutarate + erythro-4-hydroxy-L-glutamate ↔ L-glutamate + 4-hydroxy-2-oxoglutarate ,
2.6.1.39: 2-oxoglutarate + L-2-aminoadipate → L-glutamate + 2-oxoadipate ,
2.6.1.40: pyruvate + (R)-3-amino-2-methylpropanoate ↔ L-alanine + (S)-methylmalonate-semialdehyde ,
2.6.1.42: L-valine + 2-oxoglutarate → 3-methyl-2-oxobutanoate + L-glutamate ,
2.6.1.42: L-isoleucine + 2-oxoglutarate → (S)-3-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.44: glyoxylate + L-alanine ↔ glycine + pyruvate ,
2.6.1.49: L-dopa + 2-oxoglutarate ↔ 3,4-dihydroxyphenylpyruvate + L-glutamate ,
2.6.1.51: pyruvate + L-serine ↔ L-alanine + hydroxypyruvate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ← 3-phospho-hydroxypyruvate + L-glutamate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate = 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.57: 2-oxoglutarate + L-tyrosine → L-glutamate + 4-hydroxyphenylpyruvate ,
2.6.1.64: 2-oxo-3-phenylpropanoate + L-glutamine ↔ L-phenylalanine + 2-oxoglutaramate ,
2.6.1.82: 4-aminobutanal ↔ 1-pyrroline + H2O ,
2.6.1.88: L-methionine + a 2-oxo carboxylate ← 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.1.-: L-methionine + 2-oxoglutaramate ↔ 2-oxo-4-methylthiobutanoate + L-glutamine ,
2.6.1.-: 3-sulfinoalanine + 2-oxoglutarate ↔ L-glutamate + 3-sulfinopyruvate ,
2.7.1.1: a D-hexose + ATP = D-hexose 6-phosphate + ADP + H+ ,
2.7.1.1/2.7.1.2: α-D-glucose + ATP = α-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.2: D-glucopyranose + ATP → D-glucopyranose 6-phosphate + ADP + H+ ,
2.7.1.3: β-D-fructofuranose + ATP → β-D-fructofuranose 1-phosphate + ADP + H+ ,
2.7.1.6: α-D-galactose + ATP → α-D-galactose 1-phosphate + ADP + H+ ,
2.7.1.7: D-mannopyranose + ATP → α-D-mannose 6-phosphate + ADP + H+ ,
2.7.1.11: ATP + β-D-fructofuranose 6-phosphate → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.12: ATP + D-gluconate = D-gluconate 6-phosphate + ADP + H+ ,
2.7.1.14: D-sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H+ ,
2.7.1.15: α-D-ribofuranose + ATP = α-D-ribose 5-phosphate + ADP + H+ ,
2.7.1.17: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H+ ,
2.7.1.20: adenosine + ATP → AMP + ADP + H+ ,
2.7.1.22: 1-(β-D ribofuranosyl)nicotinamide + ATP = β-nicotinamide D-ribonucleotide + ADP + H+ ,
2.7.1.23: ATP + NAD+ → ADP + NADP+ + H+ ,
2.7.1.24: 3'-dephospho-CoA + ATP → ADP + coenzyme A + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP → 3'-phosphoadenylyl-sulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.28: D-glyceraldehyde + ATP → D-glyceraldehyde 3-phosphate + ADP + H+ ,
2.7.1.29: dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.31: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + H+ ,
2.7.1.32: choline + ATP → phosphocholine + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → (R)-4'-phosphopantothenate + ADP + H+ ,
2.7.1.35: ATP + pyridoxine → ADP + pyridoxine 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxal → ADP + pyridoxal 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxamine → ADP + pyridoxamine 5'-phosphate + H+ ,
2.7.1.36: (R)-mevalonate + ATP → (R)-mevalonate 5-phosphate + ADP + H+ ,
2.7.1.40: pyruvate + ATP ← phosphoenolpyruvate + ADP + H+ ,
2.7.1.48: cytidine + GTP = CMP + GDP + H+ ,
2.7.1.48: uridine + GTP = UMP + GDP + H+ ,
2.7.1.48: uridine + ATP → UMP + ADP + H+ ,
2.7.1.48: cytidine + ATP → CMP + ADP + H+ ,
2.7.1.52: L-fucopyranose + ATP → β-L-fucose 1-phosphate + ADP + H+ ,
2.7.1.59: N-acetyl-β-D-glucosamine + ATP → N-acetyl-D-glucosamine 6-phosphate + ADP + H+ ,
2.7.1.60: N-acetyl-D-mannosamine + ATP → N-acetyl-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.60: an N-acyl-D-mannosamine + ATP = an N-acyl-α-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.67: an L-1-phosphatidyl-inositol + ATP → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + H+ ,
2.7.1.68: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+ ,
2.7.1.74/2.7.1.76/2.7.1.145: 2'-deoxyadenosine + ATP → dAMP + ADP + H+ ,
2.7.1.74/2.7.1.113/2.7.1.145: 2'-deoxyguanosine + ATP → dGMP + ADP + H+ ,
2.7.1.74: 2'-deoxycytidine + a nucleoside triphosphate → dCMP + a nucleoside diphosphate + H+ ,
2.7.1.82: ethanolamine + ATP → phosphoryl-ethanolamine + ADP + H+ ,
2.7.1.91: sphinganine + ATP = sphinganine 1-phosphate + ADP + H+ ,
2.7.1.94: a 1-monoglyceride + ATP = a 1-acyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.105: β-D-fructofuranose 6-phosphate + ATP → β-D-fructose 2,6-bisphosphate + ADP + H+ ,
2.7.1.106: α-D-glucose 1-phosphate + 1,3-bisphospho-D-glycerate = α-glucose 1,6-bisphosphate + 3-phospho-D-glycerate + H+ ,
2.7.1.107: ATP + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.108: a dolichol + CTP → a dolichyl phosphate + CDP + H+ ,
2.7.1.127: D-myo-inositol (1,4,5)-trisphosphate + ATP → D-myo-inositol (1,3,4,5)-tetrakisphosphate + ADP + H+ ,
2.7.1.134: D-myo-inositol (3,4,5,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.137: an L-1-phosphatidyl-inositol + ATP → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+ ,
2.7.1.138: a ceramide + ATP = a ceramide 1-phosphate + ADP + H+ ,
2.7.1.138: a dihydroceramide + ATP = a dihydroceramide 1-phosphate + ADP + H+ ,
2.7.1.140: D-myo-inositol (1,3,4,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.145: thymidine + ATP → dTMP + ADP + H+ ,
2.7.1.145: 2'-deoxyuridine + ATP → dUMP + ADP + H+ ,
2.7.1.147: β-D-glucose + ADP = β-D-glucose 6-phosphate + AMP + H+ ,
2.7.1.147: D-glucosamine + ADP = D-glucosamine 6-phosphate + AMP + H+ ,
2.7.1.149: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+ ,
2.7.1.150: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP → 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + H+ ,
2.7.1.151: D-myo-inositol (1,4,5,6)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.151: D-myo-inositol (1,3,4,5)-tetrakisphosphate + ATP → D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+ ,
2.7.1.153: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP → 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+ ,
2.7.1.154: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP → a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+ ,
2.7.1.157: ATP + N-acetyl-α-D-galactosamine = ADP + N-acetyl-α-D-galactosamine 1-phosphate + H+ ,
2.7.1.158: D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP → 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ADP + H+ ,
2.7.1.159: D-myo-inositol (1,3,4)-trisphosphate + ATP → D-myo-inositol (1,3,4,6)-tetrakisphosphate + ADP + H+ ,
2.7.1.159: D-myo-inositol (1,3,4)-trisphosphate + ATP → D-myo-inositol (1,3,4,5)-tetrakisphosphate + ADP + H+ ,
2.7.1.-: an N-acetyl-D-galactosamine + ATP = N-acetyl-D-galactosamine 6-phosphate + ADP + H+ ,
2.7.1.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP → a diphospho-1D-myo-inositol tetrakisphosphate + ADP ,
2.7.1.-: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.11: L-glutamate[mitochondrial lumen] + ATP[mitochondrial lumen] → γ-L-glutamyl 5-phosphate[mitochondrial lumen] + ADP[mitochondrial lumen] ,
2.7.3.2: creatine + ATP ↔ creatine-phosphate + ADP + H+ ,
2.7.4.2: (R)-mevalonate 5-phosphate + ATP ↔ (R)-mevalonate diphosphate + ADP ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP = a nucleoside triphosphate + ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.10: a nucleoside triphosphate + AMP = a nucleoside diphosphate + ADP ,
2.7.4.12/2.7.4.13: dTMP + ATP → ADP + dTDP ,
2.7.4.13: ATP + dGMP → ADP + dGDP ,
2.7.4.13: ATP + dAMP → ADP + dADP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.21: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ADP ,
2.7.4.21: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + ADP ,
2.7.4.21/2.7.4.24: 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + ATP → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.4.24: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + ATP + H+ → 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + ADP ,
2.7.4.24: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ATP → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.24: 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + ATP → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.24: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + ATP → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.6.1: D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.2: thiamin + ATP → thiamin diphosphate + AMP + H+ ,
2.7.7.1: β-nicotinamide D-ribonucleotide + ATP + H+ → NAD+ + diphosphate ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.3: 4'-phosphopantetheine + ATP + H+ → 3'-dephospho-CoA + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ → UDP-α-D-glucose + diphosphate ,
2.7.7.10: α-D-galactose 1-phosphate + UTP + H+ = UDP-α-D-galactose + diphosphate ,
2.7.7.12: UDP-α-D-glucose + α-D-galactose 1-phosphate → UDP-α-D-galactose + α-D-glucose 1-phosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.14: phosphoryl-ethanolamine + CTP + H+ → CDP-ethanolamine + diphosphate ,
2.7.7.15: phosphocholine + CTP + H+ → CDP-choline + diphosphate ,
2.7.7.18: ATP + β-nicotinate D-ribonucleotide + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.22: α-D-mannose 1-phosphate + GDP + H+ = GDP-α-D-mannose + phosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.30: β-L-fucose 1-phosphate + GTP + H+ → GDP-L-fucose + diphosphate ,
2.7.7.34: α-D-glucose 1-phosphate + GTP + H+ → GDP-α-D-glucose + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.43: N-acetyl-β-neuraminate + CTP → CMP-N-acetyl-β-neuraminate + diphosphate ,
2.7.7.43: an N-acyl-β-neuraminate + CTP + H+ = a CMP-N-acyl-β-neuraminate + diphosphate ,
2.7.7.50: a 5'-diphospho-purine-[mRNA] + GTP + H+ → a 5'-(5'-triphosphoguanosine)-purine-[mRNA] + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate = a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.75: ATP + molybdopterin + H+ → molybdopterin adenine dinucleotide + diphosphate ,
2.7.7.78: GDP-α-D-glucose + phosphate ↔ α-D-glucose 1-phosphate + GDP + H+ ,
2.7.7.84: 3 ATP + H+ → pppA2'p5'A2'p5'A + 2 diphosphate ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.1: a 1,2-diacyl-sn-glycerol + CDP-ethanolamine → an L-1-phosphatidylethanolamine + CMP + H+ ,
2.7.8.2: a 1,2-diacyl-sn-glycerol + CDP-choline → a phosphatidylcholine + CMP + H+ ,
2.7.8.2: 1,2-dipalmitoylglycerol + CDP-choline → 1,2-dipalmitoyl-phosphatidylcholine + CMP + H+ ,
2.7.8.5: a CDP-diacylglycerol + sn-glycerol 3-phosphate → CMP + an L-1-phosphatidylglycerol-phosphate + H+ ,
2.7.8.11: a CDP-diacylglycerol + myo-inositol → an L-1-phosphatidyl-inositol + CMP + H+ ,
2.7.8.15: a dolichyl phosphate + UDP-N-acetyl-α-D-glucosamine → an N-acetylglucosaminyl-diphosphodolichol + UMP ,
2.7.8.17: a lysosomal-enzyme-D-mannose + UDP-N-acetyl-α-D-glucosamine = a lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose + UMP ,
2.7.8.27: a ceramide + a phosphatidylcholine ↔ a sphingomyelin + a 1,2-diacyl-sn-glycerol ,
2.7.8.29: an L-1-phosphatidylethanolamine + L-serine → an L-1-phosphatidylserine + ethanolamine ,
2.7.8.-: 2 an L-1-phosphatidyl-glycerol = a cardiolipin + glycerol ,
2.7.8.-: a phosphatidylcholine + L-serine = an L-1-phosphatidylserine + choline ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.7.10.2/2.7.12.1: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate + H+ ,
2.7.11.18: ATP + myosin light-chain + H+ = ADP + myosin light-chain phosphate ,
2.8.1.1: hydrogen cyanide + thiosulfate → sulfite + thiocyanate + 2 H+ ,
2.8.1.2: hydrogen cyanide + 3-mercaptopyruvate → pyruvate + thiocyanate + H+ ,
2.8.1.7: a [cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-cysteine → an S-sulfanyl-[cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-alanine ,
2.8.1.7: L-cystein desulfurase + L-cysteine = an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.7: an [L-cysteine desulfurase]-L-cysteine + L-cysteine → an [L-cysteine desulfurase] L-cysteine persulfide + L-alanine ,
2.8.1.7: an [L-cysteine desulfurase] L-cysteine persulfide + an unsulfurated [sulfur carrier] ↔ an [L-cysteine desulfurase]-L-cysteine + a sulfurated [sulfur carrier] ,
2.8.1.7: L-cysteine + an unsulfurated [sulfur carrier] → L-alanine + a sulfurated [sulfur carrier] ,
2.8.1.9: L-cysteine + MoO2-molybdopterin cofactor + 2 H+ → thio-molybdenum cofactor + L-alanine + H2O ,
2.8.1.12: cyclic pyranopterin phosphate + 2 a thiocarboxylated small subunit of molybdopterin synthase + H2O → 2 a small subunit of molybdopterin synthase + molybdopterin ,
2.8.2.1: a phenol + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + an aryl sulfate ,
2.8.2.1: 3,5,3'-triiodo-L-thyronine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + triiodothyronine sulfate + H+ ,
2.8.2.1: N-acetyl-serotonin + 3'-phosphoadenylyl-sulfate → N-acetyl-serotonin sulfate + adenosine 3',5'-bisphosphate ,
2.8.2.1: 3'-phosphoadenylyl-sulfate + 4-methylphenol = adenosine 3',5'-bisphosphate + 4-methylphenyl sulfate + H+ ,
2.8.2.1: 5-hydroxytryptophol + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + 5-hydroxytryptophol sulfate + H+ ,
2.8.2.1: L-thyroxine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + thyroxine sulfate + H+ ,
2.8.2.1: 6-hydroxymelatonin + 3'-phosphoadenylyl-sulfate → 6-sulfatoxymelatonin + adenosine 3',5'-bisphosphate ,
2.8.2.1: 3'-phosphoadenylyl-sulfate + indoxyl = adenosine 3',5'-bisphosphate + indoxyl sulfate + H+ ,
2.8.2.1: dopamine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H+ ,
2.8.2.1: serotonin + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + serotonin O-sulfate + H+ ,
2.8.2.2: an alcohol + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + an organosulfate + H+ ,
2.8.2.4: estrone + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + estrone-sulfate + H+ ,
2.8.2.5: [chondroitin]-N-acetyl-galactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-4-O-sulfo-N-acetylgalactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.8: [heparan]-α-D-glucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine + adenosine 3',5'-bisphosphate ,
2.8.2.11: a cerebroside + 3'-phosphoadenylyl-sulfate = a cerebroside 3-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.14: glycolithocholate + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + glycolithocholate-3-sulfate + H+ ,
2.8.2.14: taurolithocholate + 3'-phosphoadenylyl-sulfate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate + H+ ,
2.8.2.17: [chondroitin]-N-acetyl-galactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-6-O-sulfo-N-acetylgalactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.21: a keratan + 3'-phosphoadenylyl-sulfate = keratan sulfate + adenosine 3',5'-bisphosphate ,
2.8.2.23: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.29: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.30: [heparan]-α-D-glucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-glucosamine 3-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.33: [chondroitin]-4-O-sulfo-N-acetylgalactosamine + 3'-phosphoadenylyl-sulfate → [chondroitin]-4,6-di-O-sulfo-N-acetyl-D-galactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.33: [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine + 3'-phosphoadenylyl-sulfate → [dermatan]-4,6-di-O-sulfo-N-acetyl-D-galactosamine + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.35: [dermatan]-N-acetyl-D-galactosamine + 3'-phosphoadenylyl-sulfate → adenosine 3',5'-bisphosphate + [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine + H+ ,
2.8.2.-: [heparan sulfate]-α-D-N-sulfoglucosamine 6-O-sulfate + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 3,6-O-bissulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [chondroitin]-β-D-glucuronate + 3'-phosphoadenylyl-sulfate → [chondroitin-sulfate]-2-O-sulfo-β-D-glucuronate + adenosine 3',5'-bisphosphate ,
2.8.2.-: [dermatan]-α-L-iduronate + 3'-phosphoadenylyl-sulfate → [dermatan-sulfate]-2-O-sulfo-α-L-iduronate + adenosine 3',5'-bisphosphate ,
2.8.2.-: [heparan]-α-L-iduronate + 3'-phosphoadenylyl-sulfate → [heparan-sulfate]-2-O-sulfo-α-L-iduronate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan sulfate]-α-D-N-sulfoglucosamine + 3'-phosphoadenylyl-sulfate → [heparan sulfate]-α-D-N-sulfoglucosamine 6-O-sulfate + adenosine 3',5'-bisphosphate + H+ ,
2.8.2.-: [heparan]-β-D-glucuronate + 3'-phosphoadenylyl-sulfate = [heparan-sulfate]-2-O-sulfo-β-D-glucuronate + adenosine 3',5'-bisphosphate + H+ ,
2.8.3.5: succinyl-CoA + acetoacetate → succinate + acetoacetyl-CoA ,
2.8.3.5: a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate ,
2.10.1.1: molybdopterin adenine dinucleotide + molybdate + H+ → AMP + MoO2-molybdopterin cofactor + H2O ,
3.1.1.1: a carboxylic ester + H2O → an alcohol + a carboxylate + H+ ,
3.1.1.1: all-trans-retinyl palmitate + H2O → a retinol + palmitate + H+ ,
3.1.1.1: salicyl-6-hydroxy-2-cyclohexene-on-oyl + H2O → 6-hydroxy-2-cyclohexen-one-carboxylate + salicyl alcohol + H+ ,
3.1.1.1: 1-O-methylsalicylate + H2O → salicylate + methanol + H+ ,
3.1.1.1: a methyl jasmonate + H2O → a jasmonic acid + methanol + H+ ,
3.1.1.1: all-trans-retinyl palmitate + H2O → all-trans-retinol + palmitate + H+ ,
3.1.1.1: an all-trans-retinyl ester + H2O → all-trans-retinol + a long-chain fatty acid + H+ ,
3.1.1.1: methyl (indol-3-yl)acetate + H2O → indole-3-acetate + methanol + H+ ,
3.1.1.2: a phenyl acetate + H2O → a phenol + acetate + H+ ,
3.1.1.3: a dietary all-trans-retinyl ester + H2O → all-trans-retinol + a long-chain fatty acid + H+ ,
3.1.1.3: tributyrin + H2O → 1,2-dibutyrin + butanoate + H+ ,
3.1.1.3: a triglyceride + H2O → a 1,2-diglyceride + a fatty acid + H+ ,
3.1.1.4: an L-1-phosphatidylethanolamine + H2O → a fatty acid + a 1-acyl 2-lyso-phosphatidylethanolamine + H+ ,
3.1.1.4: a phosphatidylcholine + H2O → a 1-acyl 2-lyso-phosphatidylcholine + a fatty acid + H+ ,
3.1.1.4: a phosphatidylcholine + H2O → a 1-acyl 2-lyso-phosphatidylcholine + α-linolenate ,
3.1.1.5: a 2-acyl 1-lyso-phosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+ ,
3.1.1.7: acetylcholine + H2O → acetate + choline + H+ ,
3.1.1.8: an acylcholine + H2O → choline + a carboxylate + H+ ,
3.1.1.13: a steryl-ester + H2O → a sterol + a fatty acid + H+ ,
3.1.1.17: D-glucono-1,5-lactone + H2O → D-gluconate + H+ ,
3.1.1.23: a 1-monoglyceride + H2O → a fatty acid + glycerol + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.1.32: a phosphatidylcholine + H2O → a 2-acyl 1-lyso-phosphatidylcholine + a fatty acid + H+ ,
3.1.1.34: a triacyl-sn-glycerol + H2O = a carboxylate + a 1,2-diacyl-sn-glycerol + H+ ,
3.1.1.45: cis-dienelactone + H2O → 2-maleylacetate + H+ ,
3.1.1.45: trans-dienelactone + H2O → 2-maleylacetate + H+ ,
3.1.1.47: a 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O → acetate + a 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + H+ ,
3.1.1.52: an L-1-phosphatidyl-inositol + H2O → a 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H+ ,
3.1.1.53: N-acetyl-4-O-acetylneuraminate + H2O → N-acetylneuraminate + acetate + H+ ,
3.1.1.56: 4-methylumbelliferyl acetate + H2O → acetate + 4-methylumbelliferone + H+ ,
3.1.1.77: a 3-(acyloxy)acyl group of bacterial toxin + H2O → a 3-hydroxyacyl group of bacterial toxin + a fatty acid + H+ ,
3.1.1.79: a 2-monoglyceride + H2O → glycerol + a fatty acid + H+ ,
3.1.1.79: a 1,2-diglyceride + H2O → a 2-monoglyceride + a fatty acid + H+ ,
3.1.1.89: a [phosphatase 2A protein] C-terminal L-leucine methyl ester + H2O → a [phosphatase 2A protein] C-terminal L-leucine + methanol + H+ ,
3.1.1.93: mycophenolic acid O-acyl-glucuronide + H2O → mycophenolate + D-glucopyranuronate + H+ ,
3.1.1.-: [heparan]-N-acetyl-α-D-glucosamine + H2O → [heparan]-α-D-glucosamine + acetate + H+ ,
3.1.2.1: acetyl-CoA + H2O → acetate + coenzyme A + H+ ,
3.1.2.2: myristoyl-CoA + H2O → myristate + coenzyme A + H+ ,
3.1.2.2: (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + H2O → (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + coenzyme A + H+ ,
3.1.2.2: arachidoyl-CoA + H2O → arachidate + coenzyme A + H+ ,
3.1.2.2: stearoyl-CoA + H2O → stearate + coenzyme A + H+ ,
3.1.2.2: palmitoyl-CoA + H2O → palmitate + coenzyme A + H+ ,
3.1.2.2: decanoyl-CoA + H2O → decanoate + coenzyme A + H+ ,
3.1.2.2: a 2,3,4-saturated fatty acyl CoA + H2O → a 2,3,4-saturated fatty acid + coenzyme A + H+ ,
3.1.2.2: lauroyl-CoA + H2O → laurate + coenzyme A + H+ ,
3.1.2.3: succinyl-CoA + H2O → succinate + coenzyme A + H+ ,
3.1.2.4: (S)-3-hydroxy-isobutanoyl-CoA + H2O → (S)-3-hydroxy-isobutanoate + coenzyme A + H+ ,
3.1.2.4: 3-hydroxy-isobututanoyl-CoA + H2O → 3-hydroxy-isobutyrate + coenzyme A + H+ ,
3.1.2.4: 3-hydroxypropanoyl-CoA + H2O → 3-hydroxypropanoate + coenzyme A + H+ ,
3.1.2.6: (R)-S-lactoylglutathione + H2O → glutathione + (R)-lactate + H+ ,
3.1.2.6: S-(2-hydroxyacyl)glutathione + H2O → glutathione + a 2-hydroxy carboxylate ,
3.1.2.10: formyl-CoA + H2O → formate + coenzyme A + H+ ,
3.1.2.12: S-formylglutathione + H2O → formate + glutathione + H+ ,
3.1.2.20: an acyl-CoA + H2O → a carboxylate + coenzyme A + H+ ,
3.1.2.23: 4-hydroxybenzoyl-CoA + H2O → 4-hydroxybenzoate + coenzyme A + H+ ,
3.1.2.27: choloyl-CoA + H2O → cholate + coenzyme A + H+ ,
3.1.2.-: 3-trans,5-cis-tetradecadienoyl-CoA + H2O → (3E,5Z)-tetradecadienoate + coenzyme A + H+ ,
3.1.2.-: oleoyl-CoA + H2O → oleate + coenzyme A + H+ ,
3.1.3.1: a phosphate monoester + H2O → an alcohol + phosphate ,
3.1.3.2: a phosphate monoester + H2O → an alcohol + phosphate ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.4: a 1,2-diacyl-sn-glycerol 3-phosphate + H2O → a 1,2-diacyl-sn-glycerol + phosphate ,
3.1.3.5: GMP + H2O → guanosine + phosphate ,
3.1.3.5: IMP + H2O → inosine + phosphate ,
3.1.3.5: XMP + H2O → xanthosine + phosphate ,
3.1.3.5: a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.5: AMP + H2O → adenosine + phosphate ,
3.1.3.5: UMP + H2O → uridine + phosphate ,
3.1.3.5: β-nicotinamide D-ribonucleotide + H2O → 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
3.1.3.7: adenosine 3',5'-bisphosphate + H2O → AMP + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.13: 2,3-diphospho-D-glycerate + H2O → 3-phospho-D-glycerate + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.25: a myo-inositol monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 6-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 2-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 5-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 4-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 3-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.27: an L-1-phosphatidylglycerol-phosphate + H2O → an L-1-phosphatidyl-glycerol + phosphate ,
3.1.3.29: an N-acyl-β-neuraminate 9-phosphate + H2O → an N-acyl-β-neuraminate + phosphate ,
3.1.3.29: N-acetyl-β-neuraminate 9-phosphate + H2O → N-acetyl-β-neuraminate + phosphate ,
3.1.3.36: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate ,
3.1.3.46: β-D-fructose 2,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.56: D-myo-inositol (1,3,4,5)-tetrakisphosphate + H2O → D-myo-inositol (1,3,4)-trisphosphate + phosphate ,
3.1.3.56: D-myo-inositol (1,4,5)-trisphosphate + H2O → D-myo-inositol (1,4)-bisphosphate + phosphate ,
3.1.3.57: D-myo-inositol (1,3,4)-trisphosphate + H2O → D-myo-inositol (3,4)-bisphosphate + phosphate ,
3.1.3.57: D-myo-inositol (1,4)-bisphosphate + H2O → 1D-myo-inositol 4-monophosphate + phosphate ,
3.1.3.58: β-D-glucose 6-phosphate + H2O → β-D-glucose + phosphate ,
3.1.3.58: D-glucopyranose 6-phosphate + H2O → D-glucopyranose + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,3,4,5)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate ,
3.1.3.62: D-myo-inositol (1,3,4,5)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → a D myo-inositol penta kis phosphate + phosphate ,
3.1.3.62/3.1.3.72: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → 1D-myo-inositol (1,2,3,4,6)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,4,5,6)-pentakisphosphate + phosphate ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O → D-myo-inositol (1,2,3,5,6) pentakisphosphate + phosphate ,
3.1.3.64: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.66: a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate ,
3.1.3.66: D-myo-inositol (3,4)-bisphosphate + H2O → 1D-myo-inositol 3-monophosphate + phosphate ,
3.1.3.66: D-myo-inositol (1,3,4)-trisphosphate + H2O → D-myo-inositol (1,3)-bisphosphate + phosphate ,
3.1.3.67: a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate ,
3.1.3.67: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + phosphate ,
3.1.3.74: pyridoxal 5'-phosphate + H2O → pyridoxal + phosphate ,
3.1.3.74: pyridoxamine 5'-phosphate + H2O → pyridoxamine + phosphate ,
3.1.3.75: phosphocholine + H2O → choline + phosphate ,
3.1.3.75: phosphoryl-ethanolamine + H2O → ethanolamine + phosphate ,
3.1.3.77: 5-(methylthio)-2,3-dioxopentyl 1-phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate + H+ ,
3.1.3.78: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate ,
3.1.3.80: 2,3-diphospho-D-glycerate + H2O → 2-phospho-D-glycerate + phosphate ,
3.1.3.84: ADP ribose 1''-phosphate + H2O → ADP-D-ribose + phosphate ,
3.1.3.86: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate ,
3.1.3.87: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl 1-phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate ,
3.1.3.91: CMP + H2O → cytidine + phosphate ,
3.1.3.95: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate ,
3.1.3.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (1,4,5,6)-tetrakisphosphate + phosphate ,
3.1.3.-: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.-: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate ,
3.1.3.-: D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (3,4,5,6)-tetrakisphosphate + phosphate ,
3.1.3.-: D-myo-inositol (1,4,5,6)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate ,
3.1.3.-: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate ,
3.1.3.-: NADP+ + H2O → NAD+ + phosphate ,
3.1.4.1: an oligonucleotide + H2O → an oligonucleotide + a nucleoside 5'-monophosphate ,
3.1.4.3: a phosphatidylcholine + H2O → phosphocholine + a 1,2-diacyl-sn-glycerol + H+ ,
3.1.4.4: a phosphatidylcholine + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + choline + H+ ,
3.1.4.11: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → a 1,2-diacyl-sn-glycerol + D-myo-inositol (1,4)-bisphosphate + H+ ,
3.1.4.11: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O → a 1,2-diacyl-sn-glycerol + D-myo-inositol (1,4,5)-trisphosphate + H+ ,
3.1.4.12: a sphingomyelin + H2O → a ceramide + phosphocholine + H+ ,
3.1.4.17: a nucleoside cyclic 3',5'-monophosphate + H2O → a nucleoside 5'-monophosphate + H+ ,
3.1.4.35: cyclic-GMP + H2O → GMP + H+ ,
3.1.4.37: adenosine 2',3'-cyclic monophosphate + H2O → adenosine 2'-monophosphate + H+ ,
3.1.4.37: uridine 2'3'-cyclic monophosphate + H2O → uridine 2'-monophosphate + H+ ,
3.1.4.37: cytidine 2',3'-cyclic monophosphate + H2O → cytidine 2'-monophosphate + H+ ,
3.1.4.37: a nucleoside 2',3'-cyclic phosphate + H2O → a nucleoside 2'-phosphate + H+ ,
3.1.4.37: guanosine 2',3'-cyclic monophosphate + H2O → guanosine 2'-monophosphate + H+ ,
3.1.4.44: sn-glycero-3-phospho-1-inositol + H2O → myo-inositol + sn-glycerol 3-phosphate + H+ ,
3.1.4.45: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O → glycoprotein-phospho-D-mannose + N-acetyl-β-D-glucosamine + H+ ,
3.1.4.46: a glycerophosphodiester + H2O → an alcohol + sn-glycerol 3-phosphate + H+ ,
3.1.4.50: 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + 1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + H+ ,
3.1.4.54: an N-acylphosphatidylethanolamine + H2O → an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ ,
3.1.4.-: ADP ribose 1'',2''-cyclic phosphate + H2O → ADP ribose 1''-phosphate + H+ ,
3.1.6.1: a phenol sulfate + H2O → a phenol + sulfate + H+ ,
3.1.6.2: 3-β-hydroxyandrost-5-en-17-one 3-sulfate + H2O → sulfate + dehydroepiandrosterone + 3 H+ ,
3.1.6.4: [keratan]-galactose 6'-sulfate + H2O → [keratan]-galactose + sulfate + H+ ,
3.1.6.4: [chondroitin]-6-O-sulfo-N-acetylgalactosamine + H2O → [chondroitin]-N-acetyl-galactosamine + sulfate + H+ ,
3.1.6.8: a cerebroside 3-sulfate + H2O → a cerebroside + sulfate + H+ ,
3.1.6.12: [chondroitin]-4-O-sulfo-N-acetylgalactosamine + H2O → [chondroitin]-N-acetyl-galactosamine + sulfate + H+ ,
3.1.6.13: [heparan-sulfate]-2-O-sulfo-α-L-iduronate + H2O → [heparan]-α-L-iduronate + sulfate + H+ ,
3.1.6.13: [dermatan-sulfate]-2-O-sulfo-α-L-iduronate + H2O → [dermatan]-α-L-iduronate + sulfate + 2 H+ ,
3.1.6.14: [heparan sulfate]-α-N-acetyl-D-glucosamine 6-O-sulfate + H2O → [heparan]-N-acetyl-α-D-glucosamine + sulfate + H+ ,
3.1.6.14: [keratan sulfate]-α-N-acetyl-D-glucosamine 6-O-sulfate + H2O → [keratan sulfate]-α-N-acetyl-D-glucosamine + sulfate + H+ ,
3.1.6.18: [heparan-sulfate]-2-O-sulfo-β-D-glucuronate + H2O → [heparan]-β-D-glucuronate + sulfate + H+ ,
3.1.6.18: [chondroitin-sulfate]-2-O-sulfo-β-D-glucuronate + H2O → [chondroitin]-β-D-glucuronate + sulfate + 2 H+ ,
3.1.8.1: an aryl dialkyl phosphate + H2O → a dialkyl phosphate + a phenol ,
3.1.8.1: methyl parathion + H2O → 4-nitrophenol + dimethylthiophosphate + 2 H+ ,
3.1.8.1: amino-parathion + H2O → diethylthiophosphate + 4-aminophenol + H+ ,
3.1.8.1: parathion + H2O → diethylthiophosphate + 4-nitrophenol + 2 H+ ,
3.1.8.1: paraoxon + H2O → diethylphosphate + 4-nitrophenol + 2 H+ ,
3.1.11.1: DNAn + H2O → (deoxynucleotides)(n-1) + a 2'-deoxyribonucleoside 5'-monophosphate ,
3.1.11.-: DNAn + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.1: RNase II degradation substrate mRNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.3: an oligonucleotide + H2O → n a nucleoside 5'-monophosphate ,
3.1.13.4: a mRNA with poly(A) tail + n H2O → an mRNA + n AMP ,
3.1.21.1: a double stranded DNA + 2n H2O → n a 5'-phosphooligonucleotide + n a 5' phosphodinucleotide ,
3.1.22.1: a double stranded DNA + H2O → a 3' phosphooligonucleotide + a 5'-hydroxyoligonucleotide ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.11: a tRNA precursor + H2O → mature tRNA + a single-stranded oligoribonucleotide ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.27.1: RNA + H2O → a ribonucleoside 3'-phosphate + a 3' phosphooligonucleotide ,
3.1.27.5: RNA + H2O → a ribonucleoside 3'-phosphate + a 3' phosphooligonucleotide ,
3.2.1.1: starch + H2O → maltose + glucose ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → a 1,4-α-D-glucan + maltohexaose ,
3.2.1.1: starch + n H2O → a large-branched glucan ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → n a 1,4-α-D-glucan ,
3.2.1.3: {6-α-D-(1,4-α-D-glucano)-glucan}n + H2O → {6-α-D-(1,4-α-D-glucano)-glucan}n-1 + β-D-glucose ,
3.2.1.3: a debranched limit dextrin + n H2O → n β-D-glucose ,
3.2.1.10: β-isomaltose + H2O → α-D-glucose + D-glucopyranose ,
3.2.1.14: chitin + n H2O → n a chitodextrin ,
3.2.1.17: a peptidoglycan + H2O → a N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol + N-acetyl-D-glucosamine ,
3.2.1.18: a sialyloligosaccharide + H2O → an oligosaccharide + N-acetylneuraminate ,
3.2.1.20: (1,4-α-D-glucosyl)(n) + H2O → (1,4-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.20: α-maltose + H2O → 2 α-D-glucose ,
3.2.1.21: linamarin + H2O → acetone cyanohydrin + β-D-glucose ,
3.2.1.21: a β-D glucoside + H2O → a non glucosylated D-glucose acceptor + β-D-glucose ,
3.2.1.22: an α-D-galactoside + H2O → α-D-galactose + a non galactosylated galactose acceptor ,
3.2.1.22: melibiose + H2O → α-D-galactose + β-D-glucose ,
3.2.1.22: stachyose + H2O → raffinose + α-D-galactose ,
3.2.1.23: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.23: XLLG xyloglucan oligosaccharide + 2 H2O → XXXG xyloglucan oligosaccharide + 2 β-D-galactose ,
3.2.1.23: a β-D-galactoside + H2O → a non galactosylated galactose acceptor + β-D-galactose ,
3.2.1.23: 3'-ketolactose + H2O → 3-keto-β-D-galactose + β-D-glucose ,
3.2.1.23: XLXG xyloglucan oligosaccharide + H2O → XXXG xyloglucan oligosaccharide + β-D-galactose ,
3.2.1.23: XXLG xyloglucan oligosaccharide + H2O → XXXG xyloglucan oligosaccharide + β-D-galactose ,
3.2.1.24: an α-D-mannoside + H2O → α-D-mannose + a non glycosylated sugar acceptor ,
3.2.1.25: a β-D-mannoside + H2O → β-D-mannose + a non glycosylated sugar acceptor ,
3.2.1.26: β-D-fructofuranose(n) + H2O → β-D-fructofuranose(n-1) + β-D-fructofuranose ,
3.2.1.26: sucrose + H2O → α-D-glucose + β-D-fructofuranose ,
3.2.1.28: α,α-trehalose + H2O → β-D-glucose + α-D-glucose ,
3.2.1.31: a β-D-glucuronoside + H2O → D-glucopyranuronate + an alcohol ,
3.2.1.33: a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose ,
3.2.1.33: a limit dextrin + H2O → maltotetraose + a debranched limit dextrin ,
3.2.1.35: chondroitin sulfate + n H2O → n chondroitin sulfate disaccharide ,
3.2.1.35: hyaluronan + n H2O → n hyaluronate ,
3.2.1.35: dermatan sulfate + n H2O → n dermatan sulfate disaccharide ,
3.2.1.37: a (1->4)-β-D-xylan oligosaccharide + n H2O → n β-D-xylopyranose ,
3.2.1.44: a fucoidan + H2O → fucose + a fucose sulfate + an oligosaccharide ,
3.2.1.45: a D-glucosyl-N-acylsphingosine + H2O → a sphingosine ceramide + β-D-glucose ,
3.2.1.46: a D-galactosyl-N-acylsphingosine + H2O → a sphingosine ceramide + β-D-galactose ,
3.2.1.48: sucrose + H2O → β-D-fructofuranose + α-D-glucose ,
3.2.1.49: N-acetyl-α-D-glucosaminyl-[glycoprotein] + H2O → N-acetyl-α-D-galactosamine + a glycoprotein ,
3.2.1.50: an N-acetyl-α-D-glucosaminide + H2O → N-acetyl-α-D-glucosamine + a non glycosylated sugar acceptor ,
3.2.1.51: α-L-fucoside + H2O → L-fucopyranose + an alcohol ,
3.2.1.52: N,N'-diacetylchitobiose + H2O → 2 N-acetyl-D-glucosamine ,
3.2.1.52: an N-acetyl-β-D-galactosalaminyl-[glycan] + H2O → a glycan + N-acetyl-β-D-galactosamine ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.1.52: chitotriose + H2O → N,N'-diacetylchitobiose + N-acetyl-D-glucosamine ,
3.2.1.52: an N-acetyl-β-D-hexosaminide + H2O → an N-acetyl-β-D-hexosamine + an alcohol ,
3.2.1.62: glycosyl-N-acylsphingosine + H2O → a ceramide + a sugar ,
3.2.1.76: [dermatan]-α-L-iduronate + H2O → α-L-iduronate + [dermatan]-N-acetyl-D-galactosamine ,
3.2.1.84: (1,3-α-D-glucosyl)(n) + H2O → (1,3-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.96: a glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine + H2O → N-acetyl-D-glucosamine-asparagine + a glycopeptide-D-mannosyl-N4-N-acetyl-D-glucosamine ,
3.2.1.106: Glc3Man9GlcNAc2 + H2O → Glc2Man9GlcNAc2 + D-glucopyranose ,
3.2.1.108: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.113: a (mannosyl)9-(N-acetylglucosaminyl)2 + H2O → a (mannosyl)8-(N-acetylglucosaminyl)2 + D-mannose ,
3.2.1.114: a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan + 2 H2O → N4-{N-acetyl-β-D-glucosaminyl-(1,2)-α-D-mannosyl-(1,3)-[α-D-mannosyl-(1,6)]-β-D-mannosyl-(1,4)-N-acetyl-β-D-glucosaminyl-(1,4)-N-acetyl-β-D-glucosaminyl}-protein-L-asparagine + 2 α-D-mannose ,
3.2.1.127: an immunoglobulin G glycopeptide + H2O → fragments of immunoglobuline G glycopeptide + α-L-fucopyranose ,
3.2.1.130: a GlcMan9(GlcNAc)2-glycoprotein + H2O → a GlcMan8(GlcNAc)2-glycoprotein + D-glucosyl-α(1→3)- mannose ,
3.2.1.141: a maltooligosyl-trehalose + H2O = a maltodextrin + α,α-trehalose ,
3.2.1.143: poly(ADP-D-ribose)(n) + H2O → poly(ADP-D-ribose)(n-1) + ADP-D-ribose ,
3.2.1.166: heparan sulfate containing a glucuronate--N,3-O-disulfo-D-glucosamine disaccharide + n H2O → n short heparan sulfate fragments ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-L-serine-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [protein]-L-serine ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [glycoprotein]-(L-serine/L-threonine) ,
3.2.1.169: an N-acetyl-α-D-glucosaminyl-L-threonine-[glycoprotein] + H2O → N-acetyl-α-D-glucosamine + a [protein]-L-threonine ,
3.2.1.170: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate + H2O → α-D-mannose 6-phosphate + D-glycerate ,
3.2.1.183: UDP-N-acetyl-α-D-glucosamine + H2O → N-acetyl-α-D-mannosamine + UDP + H+ ,
3.2.1.-: a long-linear glucan + n H2O → a linear malto-oligosaccharide ,
3.2.2.6: NAD+ + H2O → ADP-D-ribose + nicotinamide + H+ ,
3.2.2.11: N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O → L-asparagine + N-acetyl-β-D-glucosamine ,
3.2.2.19: Nω-(ADP-D-ribosyl)-L-arginine + H2O → ADP-D-ribose + L-arginine ,
3.2.2.19: a protein-Nω-(ADP-D-ribosyl)-L-arginine + H2O → ADP-D-ribose + a [protein]-L-arginine ,
3.2.2.21: an alkylated DNA + H2O → DNAn + an alkylated nucleobase ,
3.2.2.29: a DNA containing a mismatch + H2O → a DNA containing an apyrimidinic site + thymine ,
3.3.1.1: S-adenosyl-L-homocysteine + H2O → L-homocysteine + adenosine ,
3.3.2.6: leukotriene A4 + H2O → leukotriene B4 ,
3.3.2.9: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol ,
3.3.2.10: an epoxide + H2O = a glycol ,
3.3.2.-: 7(8)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D2 ,
3.3.2.-: 4S-hydroperoxy,17S-H-docosahexaenoate → 4(5)-epoxy-17S-H-docosahexaenoate + H2O ,
3.3.2.-: 4S-hydroperoxy,17R-H-docosahexaenoate → 4(5)-epoxy-17R-H-docosahexaenoate + H2O ,
3.3.2.-: 7(8)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D1 ,
3.3.2.-: 4(5)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D3 ,
3.3.2.-: 7S-hydroperoxy,17S-H-docosahexaenoate → 7(8)-epoxy-17S-H-docosahexaenoate + H2O ,
3.3.2.-: 4(5)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D3 ,
3.3.2.-: 7(8)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D2 ,
3.3.2.-: 4(5)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D4 ,
3.3.2.-: 7(8)-epoxy-17S-H-docosahexaenoate + H2O → resolvin D1 ,
3.3.2.-: 4(5)-epoxy-17R-H-docosahexaenoate + H2O → aspirin triggered resolvin D4 ,
3.3.2.-: 7S-hydroperoxy,17R-H-docosahexaenoate → 7(8)-epoxy-17R-H-docosahexaenoate + H2O ,
3.4.11.2: a [Cys-Gly]-S-conjugate + H2O → an L-cysteine-S-conjugate + glycine ,
3.4.11.2: a polypeptide + H2O → a polypeptide + an L-amino acid ,
3.4.11.2: 4-hydroxy-2-nonenal-[Cys-Gly] conjugate + H2O → 4-hydroxy-2-nonenal-[L-Cys] conjugate + glycine ,
3.4.11.3: a protein + H2O → a peptide + a peptide ,
3.4.11.5: a peptide with an N-terminal L-proline + H2O → a peptide + L-proline ,
3.4.11.6: a protein + H2O → a peptide + a peptide ,
3.4.11.7: a [protein] N-terminal L-glutamate + H2O → L-glutamate + a protein + H+ ,
3.4.11.9: a peptide + H2O → a standard α amino acid + a peptide ,
3.4.11.14: amino acids(n) + H2O → amino acids(n-1) + a standard α amino acid ,
3.4.11.18: a peptide with an N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.11.21: a protein + H2O → a peptide + a peptide ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.13.18: a dipeptide + H2O → 2 a standard α amino acid ,
3.4.13.18: L-alanyl-L-histidine + H2O → L-alanine + L-histidine ,
3.4.13.18: L-cysteinyl-glycine + H2O → L-cysteine + glycine ,
3.4.13.18: L-alanyl-L-aspartate + H2O → L-alanine + L-aspartate ,
3.4.13.19: a dipeptide + H2O → 2 amino acids ,
3.4.13.19: leukotriene-D4 + H2O → glycine + leukotriene-E4 ,
3.4.13.20: a dipetide with L-histidine at the C-terminal + H2O → a standard α amino acid + L-histidine ,
3.4.13.21: a dipetide with an N-terminal L-aspartate + H2O → L-aspartate + a standard α amino acid ,
3.4.14.1: a peptide + n H2O → n+1 a dipeptide ,
3.4.14.2: an oligopeptide + H2O → a dipeptide + a peptide ,
3.4.14.4: an oligopeptide + H2O → a peptide + a dipeptide ,
3.4.14.5: a polypeptide + H2O → a dipeptide + a peptide ,
3.4.14.9: a polypeptide + H2O → a peptide + a tripeptide ,
3.4.14.10: a polypeptide + H2O → a peptide + a tripeptide ,
3.4.15.1: an oligopeptide + H2O → a dipeptide + a peptide ,
3.4.16.2: an oligopeptide + H2O → a peptide + a standard α amino acid ,
3.4.16.5: a peptide + H2O → a peptide + a standard α amino acid ,
3.4.16.6: a protein + H2O → a basic amino acid + a protein ,
3.4.17.11: folate + H2O → pteroate + a glutamate ,
3.4.17.12: a protein + H2O → a protein + an α amino acid ,
3.4.17.15: a peptide + H2O → a peptide + an aromatic amino acid ,
3.4.17.20: a peptide + H2O → a peptide + a basic amino acid ,
3.4.17.21: a peptide + H2O → a peptide + L-glutamate ,
3.4.17.22: a peptide + H2O → a basic amino acid + a peptide ,
3.4.18.1: a protein + H2O → a peptide + a peptide ,
3.4.19.5: a protein + H2O → a protein + L-aspartate ,
3.4.19.6: a peptide with N-terminal 5-oxo-L-proline + H2O → 5-oxoproline + a peptide ,
3.4.19.9: 4-hydroxy-2-nonenal-glutathione conjugate + H2O → 4-hydroxy-2-nonenal-[Cys-Gly] conjugate + L-glutamate ,
3.4.19.9: a glutathione-toxin conjugate + H2O → a [Cys-Gly]-S-conjugate + L-glutamate ,
3.4.19.9: tetrahydropteroyl-[γ-Glu](n) + H2O → tetrahydropteroyl-[γ-Glu](n-1) + L-glutamate ,
3.4.19.12: a ubiquitin C-terminal thioester + H2O → a ubiquitin + a thiol ,
3.4.19.13: glutathione + H2O → L-cysteinyl-glycine + L-glutamate ,
3.4.21.1: a protein + H2O → a peptide + a peptide ,
3.4.21.2: a protein + H2O → a peptide + a peptide ,
3.4.21.4: a protein + H2O → a peptide + a peptide ,
3.4.21.5: a fibrinogen + H2O → a fibrin + a fibrinopeptide A + a fibrinopeptide B ,
3.4.21.6: a prothrombin + H2O → a thrombin + a peptide + a peptide ,
3.4.21.7: a fibrin + H2O → n a peptide ,
3.4.21.9: trypsinogen + H2O → trypsin + a peptide ,
3.4.21.10: a protein + H2O → a peptide + a peptide ,
3.4.21.20: a protein + H2O → a peptide + a peptide ,
3.4.21.21: a factor X + H2O → a factor Xa + a factor Xa ,
3.4.21.22: a factor X + H2O → a factor Xa + a factor Xa ,
3.4.21.26: a protein + H2O → a peptide + a peptide ,
3.4.21.27: a factor IX + H2O → a factor IXa + a factor IXa ,
3.4.21.34: a protein + H2O → a peptide + a peptide ,
3.4.21.35: a protein + H2O → a peptide + a peptide ,
3.4.21.36: a protein + H2O → a peptide + a peptide ,
3.4.21.37: a protein + H2O → a peptide + a peptide ,
3.4.21.38: a factor VII + H2O → a factor VIIa + a factor VIIa ,
3.4.21.38: a factor XI + H2O → a factor XIa ,
3.4.21.39: a protein + H2O → a peptide + a peptide ,
3.4.21.41: complement subcomponent C1s + H2O → activated complement subcomponent C1s ,
3.4.21.43/3.4.21.47: a complement 5 α chain + H2O → a C5a anaphylatoxin + a complement C5 α' chain ,
3.4.21.45: complement component protein C4b + H2O → complement component protein C4c + complement component protein C4d ,
3.4.21.45: complement component protein C3b + H2O → complement component protein C3c + complement component protein C3d ,
3.4.21.46: complement factor B + H2O → complement factor Ba + complement factor Bb ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.59: a protein + H2O → a peptide + a peptide ,
3.4.21.68: a plasminogen + H2O → a plasmin ,
3.4.21.69: a factor Va + H2O → n a peptide ,
3.4.21.69: a factor VIIIa + H2O → n a peptide ,
3.4.21.70: a protein + H2O → a peptide + a peptide ,
3.4.21.71: a protein + H2O → a peptide + a peptide ,
3.4.21.73: a plasminogen + H2O → a plasmin ,
3.4.21.75: a protein precursor + H2O → a mature protein ,
3.4.21.76: a protein + H2O → a peptide + a peptide ,
3.4.21.77: semenogelin-1 + H2O → n fragments of semenogelin-1 ,
3.4.21.78: a protein + H2O → a peptide + a peptide ,
3.4.21.79: a protein + H2O → a peptide + a peptide ,
3.4.21.83: an oligopeptide + H2O → a peptide + a peptide ,
3.4.21.89: a peptide with a leader sequence + H2O → a peptide + a leader sequence ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.93: a protein + H2O → a peptide + a peptide ,
3.4.21.94: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.21.-: a cleaved lipoprotein signal peptide + H2O → n a peptide ,
3.4.22.1: a protein + H2O → a peptide + a peptide ,
3.4.22.15: a protein + H2O → a peptide + a peptide ,
3.4.22.16: a protein + H2O → a peptide + a peptide ,
3.4.22.27: a protein + H2O → a peptide + a peptide ,
3.4.22.34: a protein + H2O → a peptide + a peptide ,
3.4.22.36: pro-interleukin-1β + H2O → mature pro-interleukin-1β ,
3.4.22.38: a protein + H2O → a peptide + a peptide ,
3.4.22.40: a bleomycin + H2O → a deamido-bleomycin ,
3.4.22.41: a protein + H2O → a peptide + a peptide ,
3.4.22.42: a protein + H2O → a peptide + a peptide ,
3.4.22.43: a protein + H2O → a peptide + a peptide ,
3.4.23.1: a protein + H2O → a peptide + a peptide ,
3.4.23.3: a protein + H2O → a peptide + a peptide ,
3.4.23.5: a protein + H2O → a peptide + a peptide ,
3.4.23.15: an angiotensinogen + H2O → angiotensin I + a cleaved angiotensinogen ,
3.4.23.34: a protein + H2O → a peptide + a peptide ,
3.4.23.49: a protein + H2O → a peptide + a peptide ,
3.4.24.3: a collagen + H2O → n a peptide ,
3.4.24.7: a collagen + H2O → a peptide + a peptide ,
3.4.24.11: a protein + H2O → a peptide + a peptide ,
3.4.24.14: a procollagen + H2O → a cleaved procollagen + a peptide ,
3.4.24.15: a protein + H2O → a peptide + a peptide ,
3.4.24.16: an oligopeptide + H2O → a peptide + a peptide ,
3.4.24.17: a protein + H2O → a peptide + a peptide ,
3.4.24.18: a protein + H2O → a peptide + a peptide ,
3.4.24.19: a procollagen + H2O → C-terminal propeptides of procollagen + a peptide ,
3.4.24.22: a protein + H2O → a peptide + a peptide ,
3.4.24.23: a protein + H2O → a peptide + a peptide ,
3.4.24.24: a protein + H2O → a peptide + a peptide ,
3.4.24.34: a protein + H2O → a peptide + a peptide ,
3.4.24.35: a protein + H2O → a peptide + a peptide ,
3.4.24.55: a protein + H2O → n a peptide ,
3.4.24.56: a polypeptide + H2O → n a peptide ,
3.4.24.57: a O-sialoglycoprotein + H2O → n a peptide ,
3.4.24.59: mitochondrial intermediate protein + H2O → an octapeptide + a mature protein ,
3.4.24.61: a protein + H2O → a peptide + a peptide ,
3.4.24.64: a mitochondrial preprotein including a mitochondrial targeting sequence + H2O → a processed mitochondrial protein + a peptide ,
3.4.24.65: a protein + H2O → n a peptide ,
3.4.24.71: big endothelin + H2O → endothelin 1 + a peptide ,
3.4.24.81: a protein + H2O → 2 a peptide ,
3.4.24.82: aggrecan + H2O → n an aggrecan cleavage product ,
3.4.24.84: a [protein] S-farnesyl-L-cysteine + H2O → a [protein] c-terminal S-farnesyl-L-cysteine + a peptide ,
3.5.1.6: 3-ureido-isobutyrate + H2O + 2 H+ → (R)-3-amino-2-methylpropanoate + ammonium + CO2 ,
3.5.1.6: 3-ureidopropionate + H2O + 2 H+ → β-alanine + ammonium + CO2 ,
3.5.1.9: N-formylkynurenine + H2O → L-kynurenine + formate + H+ ,
3.5.1.10: an N10-formyl-tetrahydrofolate + H2O → a tetrahydrofolate + formate + H+ ,
3.5.1.12: biotin amide + H2O = ammonium + biotin ,
3.5.1.14: an N-acylated aliphatic-L-amino acid + H2O = a carboxylate + an aliphatic L-amino acid ,
3.5.1.15: an N-acyl-L-aspartate + H2O → L-aspartate + a carboxylate ,
3.5.1.15: N-acetyl-L-aspartate + H2O = L-aspartate + acetate ,
3.5.1.23: an α hydroxyphytoceramide + H2O ↔ phytosphingosine + a hydroxy fatty acid ,
3.5.1.23: a ceramide + H2O = a sphingoid base + a fatty acid ,
3.5.1.23: a sphingosine ceramide + H2O → sphingosine + a fatty acid ,
3.5.1.25: N-acetyl-D-galactosamine 6-phosphate + H2O = acetate + D-galactosamine 6-phosphate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.26: N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O → N-acetyl-β-glucosaminylamine + L-aspartate + H+ ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O = N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine ,
3.5.1.38: L-asparagine + H2O → L-aspartate + ammonium ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.52: a [protein]-N4-(N-acetyl-β-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-β-glucosaminylamine + a [protein]-L-aspartate + H+ ,
3.5.1.63: 4-acetamidobutanoate + H2O → 4-aminobutanoate + acetate ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O = a [protein] N-terminal L-methionine + formate ,
3.5.1.89: a 6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O = 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate ,
3.5.1.92: pantetheine + H2O = (R)-pantothenate + cysteamine ,
3.5.1.99: anandamide + H2O → arachidonate + ethanolamine ,
3.5.1.99: oleamide + H2O = oleate + ammonium ,
3.5.1.109: a D-glucosyl-N-acylsphingosine + H2O = a fatty acid + D-glucosyl-sphingosine ,
3.5.1.109: an N-acyl-sphingosylphosphorylcholine + H2O → a fatty acid + sphingosylphosphorylcholine ,
3.5.1.111: 2-oxoglutaramate + H2O → 2-oxoglutarate + ammonium ,
3.5.2.2: hydantoin + H2O = N-carbamoylglycine + H+ ,
3.5.2.2: 5,6-dihydrothymine + H2O → 3-ureido-isobutyrate + H+ ,
3.5.2.2: 5,6-dihydrouracil + H2O → 3-ureidopropionate + H+ ,
3.5.2.3: (S)-dihydroorotate + H2O ← N-carbamoyl-L-aspartate + H+ ,
3.5.2.7: 4-imidazolone-5-propionate + H2O → N-formimino-L-glutamate ,
3.5.2.9: 5-oxoproline + ATP + 2 H2O → L-glutamate + ADP + phosphate + H+ ,
3.5.3.1: L-arginine + H2O → urea + L-ornithine ,
3.5.3.4: allantoate + H2O = S-ureidoglycolate + urea ,
3.5.3.11: agmatine + H2O → urea + putrescine ,
3.5.3.18: N6,N6-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline ,
3.5.4.3: guanine + H+ + H2O → ammonium + xanthine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.5: cytidine + H+ + H2O → uridine + ammonium ,
3.5.4.5: 2'-deoxycytidine + H+ + H2O → 2'-deoxyuridine + ammonium ,
3.5.4.9: a 5,10-methenyltetrahydrofolate + H2O ↔ an N10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ← 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.12: dCMP + H+ + H2O → ammonium + dUMP ,
3.5.4.16: GTP + H2O → formate + 7,8-dihydroneopterin 3'-triphosphate + H+ ,
3.5.4.17: AMP + H+ + H2O → IMP + ammonium ,
3.5.5.1: indole-3-acetonitrile + 2 H2O = ammonium + indole-3-acetate ,
3.5.5.1: a nitrile + 2 H2O = a carboxylate + ammonium ,
3.5.99.6: α-D-glucosamine 6-phosphate + H2O ↔ β-D-fructofuranose 6-phosphate + ammonium ,
3.5.99.10: 2-iminopropanoate + H+ + H2O → pyruvate + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.5: a nucleoside triphosphate + 2 H2O → a nucleoside 5'-monophosphate + 2 phosphate + 2 H+ ,
3.6.1.5: ATP + 2 H2O → AMP + 2 phosphate + 2 H+ ,
3.6.1.5: CTP + 2 H2O → CMP + 2 phosphate + 2 H+ ,
3.6.1.5: ADP + H2O = AMP + phosphate + H+ ,
3.6.1.5: UTP + 2 H2O → UMP + 2 phosphate + 2 H+ ,
3.6.1.6: CDP + H2O → CMP + phosphate + H+ ,
3.6.1.6: a nucleoside diphosphate + H2O = a nucleoside 5'-monophosphate + phosphate + H+ ,
3.6.1.6: UDP + H2O → UMP + phosphate + H+ ,
3.6.1.6: dCDP + H2O → dCMP + phosphate + H+ ,
3.6.1.7: an acyl phosphate + H2O = a carboxylate + phosphate + H+ ,
3.6.1.9: a dinucleotide (nucleic acid) + H2O = 2 a nucleoside 5'-monophosphate + 2 H+ ,
3.6.1.9: NADH + H2O = NMNH + AMP + 2 H+ ,
3.6.1.14: adenosine tetraphosphate + H2O = ATP + phosphate + 2 H+ ,
3.6.1.14: adenosine pentaphosphate + H2O = adenosine tetraphosphate + phosphate + H+ ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.15: UTP + H2O → UDP + phosphate + H+ ,
3.6.1.15: a nucleoside triphosphate + H2O → a nucleoside diphosphate + phosphate + H+ ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.16: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+ ,
3.6.1.17: P1,P4-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP + 2 H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.19: ITP + H2O = IMP + diphosphate + H+ ,
3.6.1.19: a nucleoside triphosphate + H2O → a nucleoside 5'-monophosphate + diphosphate + H+ ,
3.6.1.19: dGTP + H2O → dGMP + diphosphate + H+ ,
3.6.1.21: an ADP-sugar + H2O = AMP + an α-D-aldose 1-phosphate ,
3.6.1.28: thiamin triphosphate + H2O = thiamin diphosphate + phosphate + H+ ,
3.6.1.29: 5',5'''-diadenosine triphosphate + H2O = AMP + ADP + 2 H+ ,
3.6.1.43: dolichyl diphosphate + H2O = a dolichyl phosphate + phosphate + H+ ,
3.6.1.45: a UDP-sugar + H2O → UMP + an α-D-aldose 1-phosphate + 2 H+ ,
3.6.1.52: 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: a diphospho-1D-myo-inositol tetrakisphosphate + H2O = D-myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: a pyrophosphate-containing inositol phosphate + H2O = a myo-inositol-polyphosphate + phosphate ,
3.6.1.52: 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.52: 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + H2O = 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + phosphate + H+ ,
3.6.1.52: 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+ ,
3.6.1.53: CDP-choline + H2O = CMP + phosphocholine + 2 H+ ,
3.6.1.53: ADP-D-ribose + H2O = AMP + D-ribofuranose 5-phosphate + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.56: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate + H+ ,
3.6.1.58: 8-oxo-dGDP + H2O → 8-oxo-dGMP + phosphate + H+ ,
3.6.1.60: 5',5'''-diadenosine pentaphosphate + H2O = adenosine tetraphosphate + AMP + H+ ,
3.6.1.60: 5',5'''-diadenosine hexaphosphate + H2O = adenosine pentaphosphate + AMP + H+ ,
3.6.1.65: dCTP + H2O = dCMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GDP + H2O → 8-oxo-GMP + phosphate + H+ ,
3.6.1.-: 8-oxo-dADP + H2O → 8-oxo-dAMP + phosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.3.1: a phospholipid[out] + ATP + H2O → a phospholipid[cytosol] + ADP + phosphate + H+ ,
3.6.3.4: Cu2+[cytosol] + ATP + H2O ↔ Cu2+[golgi lumen] + ADP + phosphate + 2 H+ ,
3.6.3.4: Cu2+[cytosol] + ATP + H2O → Cu2+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[endoplasmic reticulum lumen] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.8: Ca2+[cytosol] + ATP + H2O ↔ Ca2+[golgi lumen] + ADP + phosphate + H+ ,
3.6.3.9: 2 K+[extracellular space] + 3 Na+[cytosol] + ATP + H2O → 2 K+[cytosol] + 3 Na+[extracellular space] + ADP + phosphate + H+ ,
3.6.3.10: K+[extracellular space] + ATP + H+[cytosol] + H2O → ADP + K+[cytosol] + phosphate + H+[cytosol] + H+[cytosol] ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.44: a xenobiotic[cytosol] + ATP + H2O ↔ a xenobiotic[extracellular space] + ADP + phosphate ,
3.6.3.49: chloride[out] + ATP + H2O ↔ chloride[cytosol] + ADP + phosphate + H+ ,
3.6.3.-: Ca2+[in] + ATP + H2O ↔ Ca2+[out] + ADP + phosphate + H+ ,
3.6.3.-: Cu2+[out] + ATP + H2O ↔ Cu2+[in] + ADP + phosphate + H+ ,
3.6.4.3: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.4: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.6: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.7: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.12: a double-helix DNA + ATP + H2O → an unwound double-stranded DNA + ADP + phosphate + H+ ,
3.6.4.13: ATP + H2O = ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
3.7.1.2: 4-fumaryl-acetoacetate + H2O → fumarate + acetoacetate + H+ ,
3.7.1.3: L-kynurenine + H2O ← L-alanine + anthranilate + H+ ,
3.7.1.3: 3-hydroxy-L-kynurenine + H2O → 3-hydroxyanthranilate + L-alanine + H+ ,
3.10.1.1: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate ,
3.13.1.-: 3-sulfinopyruvate + H2O → sulfite + pyruvate + H+ ,
4.1.1.4: acetoacetate + H+ → acetone + CO2 ,
4.1.1.6: cis-aconitate + H+ = CO2 + itaconate ,
4.1.1.9: malonyl-CoA + H+ → CO2 + acetyl-CoA ,
4.1.1.15: L-glutamate + H+ → CO2 + 4-aminobutanoate ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.19: L-arginine + H+ → CO2 + agmatine ,
4.1.1.21: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ ← 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 ,
4.1.1.22: L-histidine + H+ = CO2 + histamine ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.25: L-tyrosine + H+ → CO2 + tyramine ,
4.1.1.28: 5-hydroxy-L-tryptophan + H+ → serotonin + CO2 ,
4.1.1.28: L-tryptophan + H+ → CO2 + tryptamine ,
4.1.1.28: L-dopa + H+ → dopamine + CO2 ,
4.1.1.29: 3-sulfinoalanine + H+ → CO2 + hypotaurine ,
4.1.1.32: oxaloacetate + ITP = CO2 + phosphoenolpyruvate + IDP ,
4.1.1.32: oxaloacetate + GTP → CO2 + phosphoenolpyruvate + GDP ,
4.1.1.33: (R)-mevalonate diphosphate + ATP → isopentenyl diphosphate + CO2 + ADP + phosphate ,
4.1.1.34: 3-keto-L-gulonate + H+ → L-xylulose + CO2 ,
4.1.1.35: UDP-α-D-glucuronate + H+ → UDP-α-D-xylose + CO2 ,
4.1.1.36: R-4'-phosphopantothenoyl-L-cysteine + H+ → 4'-phosphopantetheine + CO2 ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → 4 CO2 + coproporphyrinogen III ,
4.1.1.37: uroporphyrinogen-I + 4 H+ = coproporphyrinogen I + 4 CO2 ,
4.1.1.41: (S)-methylmalonyl-CoA + H+ = CO2 + propanoyl-CoA ,
4.1.1.45: aminocarboxymuconate semialdehyde + H+ → CO2 + 2-aminomuconate 6-semialdehyde ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.65: an L-1-phosphatidylserine + H+ = an L-1-phosphatidylethanolamine + CO2 ,
4.1.1.70: (E)-glutaconyl-CoA + H+ ↔ CO2 + crotonyl-CoA ,
4.1.1.84: D-dopachrome + H+ = 5,6-dihydroxyindole + CO2 ,
4.1.1.90: a [protein] 4-carboxy-L-glutamate + vitamin K 2,3-epoxide + H2O = phylloquinone + a [protein]-α-L-glutamate + CO2 + oxygen + H+ ,
4.1.1.94: (S)-ethylmalonyl-CoA + H+ = butanoyl-CoA + CO2 ,
4.1.1.-: 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 ,
4.1.1.-: a 3-oxoacid + H+ → a methyl ketone + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate → acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.13: β-D-fructofuranose 1-phosphate → dihydroxyacetone phosphate + D-glyceraldehyde ,
4.1.2.27: sphinganine 1-phosphate = palmitaldehyde + phosphoryl-ethanolamine ,
4.1.2.30: 17-α-hydroxypregnenolone → dehydroepiandrosterone + acetaldehyde ,
4.1.3.3: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate ,
4.1.3.4: (S)-3-hydroxy-3-methylglutaryl-CoA → acetoacetate + acetyl-CoA ,
4.1.3.6: citrate = acetate + oxaloacetate ,
4.1.3.16: 4-hydroxy-2-oxoglutarate → glyoxylate + pyruvate ,
4.1.3.44: N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine → 4-demethylwyosine37 in tRNAPhe + L-methionine + 5'-deoxyadenosine + CO2 + H2O ,
4.1.99.14: (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA) = thymidylyl-(3'-5')-thymidylate (in DNA) ,
4.1.99.18: GTP → cyclic pyranopterin phosphate + diphosphate ,
4.1.-.-: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA → a 2-methyl branched 2,3,4-saturated fatty aldehyde + formyl-CoA ,
4.1.-.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA → an odd numbered straight chain 2,3,4-saturated fatty aldehyde + formyl-CoA ,
4.2.1.1: carbonic acid = CO2 + H2O ,
4.2.1.1: hydrogen carbonate + H+ = CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.3: citrate = D-threo-isocitrate ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.17: 3-hydroxyadipyl-CoA = 2,3-didehydroadipyl-CoA + H2O ,
4.2.1.17: (S)-3-hydroxy-isobutanoyl-CoA ← methylacrylyl-CoA + H2O ,
4.2.1.17: OPC4-3-hydroxyacyl-CoA = OPC4-trans-2-enoyl-CoA + H2O ,
4.2.1.17: a (3S)-3-hydroxyacyl-CoA ← a trans-2-enoyl-CoA + H2O ,
4.2.1.17: OPC6-3-hydroxyacyl-CoA = OPC6-trans-2-enoyl-CoA + H2O ,
4.2.1.17: 3-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA = 4-coumaryl-CoA + H2O ,
4.2.1.17: (3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA ← (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O ,
4.2.1.17: OPC8-3-hydroxyacyl-CoA = OPC8-trans-2-enoyl-CoA + H2O ,
4.2.1.17: a (3R)-3-hydroxyacyl-CoA = a cis-2-enoyl-CoA + H2O ,
4.2.1.17: (S)-3-hydroxydecanoyl-CoA ← trans-Δ2-decenoyl-CoA + H2O ,
4.2.1.17: 2-methyl-3-hydroxybutyryl-CoA ← (E)-2-methylcrotonoyl-CoA + H2O ,
4.2.1.18: (S)-3-hydroxy-3-methylglutaryl-CoA ← 3-methylglutaconyl-CoA + H2O ,
4.2.1.22: L-homocysteine + L-serine → L-cystathionine + H2O ,
4.2.1.24: 2 5-aminolevulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.46: dTDP-α-D-glucose = dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O ,
4.2.1.47: GDP-α-D-mannose → GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.49: 4-imidazolone-5-propionate ← urocanate + H2O ,
4.2.1.55: (R)-3-hydroxybutanoyl-CoA = crotonyl-CoA + H2O ,
4.2.1.70: D-ribofuranose 5-phosphate + uracil = pseudouridine 5'-phosphate + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.77: trans-3-hydroxy-L-proline = Δ1-pyrroline-2-carboxylate + H2O + H+ ,
4.2.1.93: ATP + (S)-NADHX → ADP + NADH + phosphate + H+ ,
4.2.1.93: (S)-NADPHX + ATP = ADP + NADPH + phosphate + H+ ,
4.2.1.96: 4α-hydroxy-tetrahydrobiopterin → 7,8-dihydrobiopterin + H2O ,
4.2.1.107: (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA ← (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + H2O ,
4.2.1.107: (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + H2O → (24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA ,
4.2.1.109: 5-methylthioribulose 1-phosphate → 5-(methylthio)-2,3-dioxopentyl 1-phosphate + H2O ,
4.2.1.119: a (3R)-3-hydroxyacyl-CoA ↔ a trans-2-enoyl-CoA + H2O ,
4.2.1.134: a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H2O ,
4.2.1.134: 3R-hydroxy-(11Z,14Z)-icosa-11,14-dienoyl-CoA → (2E, 11Z,14Z)-icosa-2,11,14-trienoyl-CoA + H2O ,
4.2.1.134: (5Z,8Z,11Z,14Z,17Z)-3R-hydroxy-docosapentaenoyl-CoA → (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O ,
4.2.1.134: 3-hydroxy-eicosatetraenoyl-CoA → (2E,8Z,11Z,14Z,17Z)-icosa-2,8,11,14,17-pentaenoyl-CoA + H2O ,
4.2.1.134: 3R-hydroxy-tetracosapentaenoyl-CoA → (2Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O ,
4.2.1.150: (S)-3-hydroxybutanoyl-CoA ← crotonyl-CoA + H2O ,
4.2.1.-: (3R)-3-hydroxy-stearoyl-CoA → trans-octadec-2-enoyl-CoA + H2O ,
4.2.1.-: benzyl-6-hydroxy-2-cyclohexene-on-oyl + H2O = 6-hydroxy-2-cyclohexen-one-carboxylate + benzyl alcohol + H+ ,
4.2.3.12: 7,8-dihydroneopterin 3'-triphosphate → PPPi + 6-pyruvoyl tetrahydropterin + H+ ,
4.3.1.3: L-histidine → ammonium + urocanate ,
4.3.1.4: a 5-formiminotetrahydrofolate + 2 H+ → ammonium + a 5,10-methenyltetrahydrofolate ,
4.3.1.17: L-serine → pyruvate + ammonium ,
4.3.1.19: L-threonine → 2-oxobutanoate + ammonium ,
4.3.2.1: L-arginino-succinate ↔ L-arginine + fumarate ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.2.5: a C-terminal [protein]-hydroxyglycine = a peptidyl amide + glyoxylate ,
4.3.2.-: sphingosine 1-phosphate → 2-trans-hexadecenal + phosphoryl-ethanolamine ,
4.4.1.1: L-homoserine → 2-oxobutanoate + ammonium ,
4.4.1.1/4.4.1.-: L-cysteine + H2O → pyruvate + hydrogen sulfide + ammonium ,
4.4.1.1: L-cystathionine + H2O → 2-oxobutanoate + L-cysteine + ammonium ,
4.4.1.1: L-cystine + H2O → thiocysteine + pyruvate + ammonium ,
4.4.1.5: (R)-S-lactoylglutathione ← methylglyoxal + glutathione ,
4.4.1.13: an L-cysteine-S-conjugate + H2O → pyruvate + a thiol + ammonium ,
4.4.1.16: L-selenocysteine + an unknown reduced electron acceptor = L-alanine + selenide + an unknown oxidized electron acceptor + 2 H+ ,
4.4.1.20: leukotriene-C4 ← leukotriene A4 + glutathione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.6.1.1: ATP = cyclic-AMP + diphosphate ,
4.6.1.2: GTP = cyclic-GMP + diphosphate ,
4.6.1.15: FAD = AMP + riboflavin cyclic-4',5'-phosphate ,
4.6.1.16: a polycistronic tRNA precursor → a tRNA intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus + a 3' half-tRNA molecule with a hydroxyl on its 5' end + a 5' half-tRNA molecule with a 2',3' cyclic phosphate on its 3' end ,
4.99.1.1: protoporphyrin IX + Fe2+ → ferroheme b + 2 H+ ,
5.1.1.18: L-serine = D-serine ,
5.1.2.3: a (3R)-3-hydroxyacyl-CoA → a (3S)-3-hydroxyacyl-CoA ,
5.1.3.1: D-ribulose 5-phosphate → D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: β-D-galactose → α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.7: UDP-N-acetyl-α-D-glucosamine → UDP-N-acetyl-α-D-galactosamine ,
5.1.3.8: an N-acyl-D-glucosamine = an N-acyl-D-mannosamine ,
5.1.3.14: UDP-N-acetyl-α-D-glucosamine = UDP-N-acetyl-α-D-mannosamine ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.17: [heparan]-β-D-glucuronate ↔ [heparan]-α-L-iduronate ,
5.1.3.19: [chondroitin]-β-D-glucuronate → [dermatan]-α-L-iduronate ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.1.99.1: (R)-methylmalonyl-CoA ← (S)-methylmalonyl-CoA ,
5.1.99.4: a (2S)-2-methylacyl-CoA ↔ a (2R)-2-methylacyl-CoA ,
5.1.99.4: (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA ↔ (25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA ,
5.1.99.4: (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ↔ (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ,
5.1.99.6: (R)-NADHX → (S)-NADHX ,
5.2.1.2: 4-maleyl-acetoacetate → 4-fumaryl-acetoacetate ,
5.2.1.8: peptidylproline (ω = 180) = peptidylproline (ω = 0) ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.6: D-ribose 5-phosphate ← D-ribulose 5-phosphate ,
5.3.1.8: α-D-mannose 6-phosphate ← β-D-fructofuranose 6-phosphate ,
5.3.1.9: D-glucopyranose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: α-D-glucose 6-phosphate = β-D-fructofuranose 6-phosphate ,
5.3.1.22: hydroxypyruvate = tartronate semialdehyde ,
5.3.1.23: S-methyl-5-thio-α-D-ribose 1-phosphate → 5-methylthioribulose 1-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.5: 5-(methylthio)-2,3-dioxopentyl 1-phosphate → 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl 1-phosphate + H+ ,
5.3.2.8: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate ↔ (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
5.3.3.1: cholest-5-en-3-one = cholest-4-en-3-one ,
5.3.3.1: pregn-5-ene-3,20-dione-17-ol = 17-α-hydroxyprogesterone ,
5.3.3.1: 3-oxo-24-ethyl-cholest-5-ene = 3-oxo-24-ethyl-cholest-4-ene ,
5.3.3.1: pregn-5-ene-3,20-dione → progesterone ,
5.3.3.1: campesterol = campest-4-en-3β-ol ,
5.3.3.1: a 3-oxo-δ5-steroid = a 3-oxo-Δ4-steroid ,
5.3.3.1: 5-androstene-3,17-dione → androst-4-ene-3,17-dione ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.5: zymosterol → 5α-cholesta-7,24-dien-3β-ol ,
5.3.3.5: lathosterol ← zymostenol ,
5.3.3.8: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA ,
5.3.3.8: a trans-3-enoyl-CoA = a trans-2-enoyl-CoA ,
5.3.3.8: a trans2,cis-5-dienoyl-CoA = a trans3,cis-5-dienoyl-CoA ,
5.3.3.8: a cis-3-enoyl-CoA → a trans-2-enoyl-CoA ,
5.3.3.12: L-dopachrome → 5,6-dihydroxyindole-2-carboxylate ,
5.3.3.-: a trans3,cis-5-dienoyl-CoA = a trans-2,trans-4-dienoyl-CoA ,
5.3.99.2: prostaglandin-H2 → prostaglandin D2 ,
5.3.99.3: prostaglandin-H2 → prostaglandin E2 ,
5.3.99.4: prostaglandin-H2 → prostaglandin I2 ,
5.3.99.5: prostaglandin-H2 → thromboxane A2 ,
5.4.1.-: α-lactose = allolactose ,
5.4.2.3: N-acetyl-α-D-glucosamine 1-phosphate ← N-acetyl-D-glucosamine 6-phosphate ,
5.4.2.4: 1,3-bisphospho-D-glycerate → 2,3-diphospho-D-glycerate + H+ ,
5.4.2.5: α-D-glucose 1-phosphate → D-glucopyranose 6-phosphate ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate → D-ribose 5-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ← α-D-mannose 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.99.2: (R)-methylmalonyl-CoA → succinyl-CoA ,
5.4.99.7: (3S)-2,3-epoxy-2,3-dihydrosqualene = lanosterol ,
5.4.99.25: a uridine55 in tRNA = a tRNA pseudouridine55 ,
5.4.99.26: a uridine65 in tRNA = a tRNA pseudouridine65 ,
5.4.99.27: a uridine13 in tRNA = a pseudouridine13 in tRNA ,
5.4.99.28: a uridine32 in tRNA = a pseudouridine32 in tRNA ,
5.5.1.4: D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate ,
5.5.1.4: β-D-glucose 6-phosphate = 1D-myo-inositol 3-monophosphate ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.2: a carboxylate + ATP + coenzyme A → an acyl-CoA + AMP + diphosphate ,
6.2.1.3: pristanate + ATP + coenzyme A → pristanoyl-CoA + AMP + diphosphate ,
6.2.1.3: ATP + α-linolenate + coenzyme A → α-linolenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: decanoate + ATP + coenzyme A → decanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + ATP + coenzyme A → (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + AMP + diphosphate ,
6.2.1.3: (15Z)-tetracosenoate + ATP + coenzyme A → (Z)-15-tetracosenoyl-CoA + AMP + diphosphate ,
6.2.1.3: linoleate + ATP + coenzyme A → linoleoyl-CoA + AMP + diphosphate ,
6.2.1.3: palmitate + ATP + coenzyme A → palmitoyl-CoA + AMP + diphosphate ,
6.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: octanoate + ATP + coenzyme A → octanoyl-CoA + AMP + diphosphate ,
6.2.1.3: phytenate + ATP + coenzyme A → phytenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a long-chain fatty acid + ATP + coenzyme A → a long-chain acyl-CoA + AMP + diphosphate ,
6.2.1.3: oleate + ATP + coenzyme A → oleoyl-CoA + AMP + diphosphate ,
6.2.1.4: succinate[mitochondrial lumen] + GTP[mitochondrial lumen] + coenzyme A[mitochondrial lumen] ↔ succinyl-CoA[mitochondrial lumen] + GDP[mitochondrial lumen] + phosphate[mitochondrial lumen] ,
6.2.1.5: succinate[mitochondrial lumen] + ATP[mitochondrial lumen] + coenzyme A[mitochondrial lumen] ↔ succinyl-CoA[mitochondrial lumen] + ADP[mitochondrial lumen] + phosphate[mitochondrial lumen] ,
6.2.1.7: (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + ATP + coenzyme A → (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA + AMP + diphosphate ,
6.2.1.7: ATP + cholate + coenzyme A → AMP + choloyl-CoA + diphosphate ,
6.2.1.12: 4-coumarate + ATP + coenzyme A → 4-coumaryl-CoA + AMP + diphosphate ,
6.2.1.15: arachidonate + ATP + coenzyme A → arachidonyl-CoA + AMP + diphosphate ,
6.2.1.16: acetoacetate + ATP + coenzyme A → acetoacetyl-CoA + AMP + diphosphate ,
6.2.1.24: phytanate + ATP + coenzyme A → phytanoyl-CoA + AMP + diphosphate ,
6.2.1.28: ATP + (25R)-3α,7α-dihydroxy-5-β-cholestanate + coenzyme A → AMP + (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + diphosphate ,
6.2.1.41: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + coenzyme A → 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate ,
6.2.1.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.-: 3-oxocholest-4-en-26-oate + ATP + coenzyme A → 3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate ,
6.2.1.-: 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoate + ATP + coenzyme A → OPC8-CoA + AMP + diphosphate ,
6.3.1.1: L-aspartate + ammonium + ATP → L-asparagine + AMP + diphosphate + H+ ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.14: a diphthine-[translation elongation factor 2] + ammonium + ATP → a diphthamide-[translation elongation factor 2] + AMP + diphosphate + H+ ,
6.3.2.2: L-cysteine + L-glutamate + ATP → γ-L-glutamyl-L-cysteine + ADP + phosphate + H+ ,
6.3.2.3: glycine + γ-L-glutamyl-L-cysteine + ATP → glutathione + ADP + phosphate + H+ ,
6.3.2.5: (R)-4'-phosphopantothenate + L-cysteine + CTP → R-4'-phosphopantothenoyl-L-cysteine + CMP + diphosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.11: β-alanine + L-histidine + ATP → carnosine + ADP + phosphate + H+ ,
6.3.2.11: 4-aminobutanoate + L-histidine + ATP → homocarnosine + ADP + phosphate + H+ ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: (R)-4'-phosphopantothenate + L-cysteine + ATP → R-4'-phosphopantothenoyl-L-cysteine + AMP + diphosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: an N5-formyl-tetrahydrofolate + ATP → a 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.3: a tetrahydrofolate + ATP + formate → 10-formyl-tetrahydropteroyl-[γ-Glu](n) + ADP + phosphate ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.11: an apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + biotin + ATP → a holo [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + AMP + diphosphate ,
6.3.4.13: ATP + 5-phospho-β-D-ribosylamine + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.16: ammonium + CO2 + 2 ATP + H2O → carbamoyl-phosphate + 2 ADP + phosphate + 3 H+ ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → L-glutamate + AMP + NAD+ + diphosphate + H+ ,
6.3.5.2: XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+ ,
6.3.5.4: L-glutamine + L-aspartate + ATP + H2O → L-glutamate + L-asparagine + AMP + diphosphate + H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.4.1.1: hydrogen carbonate[mitochondrial lumen] + pyruvate[mitochondrial lumen] + ATP[mitochondrial lumen] → oxaloacetate[mitochondrial lumen] + ADP[mitochondrial lumen] + phosphate[mitochondrial lumen] + H+[mitochondrial lumen] ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.3: ATP + hydrogen carbonate + propanoyl-CoA → (S)-methylmalonyl-CoA + ADP + phosphate + H+ ,
6.4.1.4: hydrogen carbonate + 3-methylcrotonyl-CoA + ATP → ADP + 3-methylglutaconyl-CoA + phosphate + H+ ,
6.5.1.6: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
6.5.1.7: (deoxynucleotides)(m) + ATP + (deoxynucleotides)(n) → (deoxynucleotides)(n+m) + AMP + diphosphate ,
6.-.-.-: a uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + H+ → a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
L-glutamate[mitochondrial lumen] + H+[mitochondrial lumen] ↔ L-glutamate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] ,
an O-acyl-L-carnitine[mitochondrial intermembrane space] ↔ an O-acyl-L-carnitine[cytosol] ,
hydrogen carbonate[extracellular space] + Na+[extracellular space] + chloride[cytosol] → hydrogen carbonate[cytosol] + Na+[cytosol] + chloride[extracellular space] ,
L-tyrosine[extracellular space] → L-tyrosine[cytosol] ,
L-aspartate[extracellular space] + Na+[extracellular space] → L-aspartate[cytosol] + Na+[cytosol] ,
β-D-glucose[extracellular space] → β-D-glucose[cytosol] ,
Na+[extracellular space] → Na+[cytosol] ,
(S)-malate[mitochondrial intermembrane space] ↔ (S)-malate[cytosol] ,
pyruvate[cytosol] ↔ pyruvate[mitochondrial intermembrane space] ,
(R)-noradrenaline[extracellular space] + Na+[extracellular space] → (R)-noradrenaline[cytosol] + Na+[cytosol] ,
K+[out] → K+[in] ,
3'-phosphoadenylyl-sulfate[cytosol] → 3'-phosphoadenylyl-sulfate[golgi lumen] ,
(R)-3-hydroxybutanoate[extracellular space] + H+[extracellular space] → (R)-3-hydroxybutanoate[cytosol] + H+[cytosol] ,
4-aminobutanoate[cytosol] → 4-aminobutanoate[vesicle lumen] ,
4-aminobutanoate[extracellular space] + Na+[extracellular space] + chloride[extracellular space] → 4-aminobutanoate[cytosol] + Na+[cytosol] + chloride[cytosol] ,
an mRNA + H2O = an RNase product with a 3' phosphate + an RNase product with a 5' OH ,
L-glutamate[out] + L-aspartate[in] + H+[out] → L-glutamate[in] + L-aspartate[out] + H+[in] ,
Na+[extracellular space] + L-glutamine[extracellular space] → L-glutamine[cytosol] + Na+[cytosol] ,
D-glucose[extracellular space] + 2 Na+[extracellular space] → D-glucose[cytosol] + 2 Na+[cytosol] ,
4 H+[in] → 4 H+[out] ,
L-valine[extracellular space] + Na+[extracellular space] → L-valine[cytosol] + Na+[cytosol] ,
lactate[extracellular space] + H+[extracellular space] → lactate[cytosol] + H+[cytosol] ,
L-cystine[extracellular space] → L-cystine[cytosol] ,
phosphate[mitochondrial intermembrane space] ↔ phosphate[cytosol] ,
L-glutamate[extracellular space] + Na+[extracellular space] → L-glutamate[cytosol] + Na+[cytosol] ,
L-glutamate[cytosol] → L-glutamate[vesicle lumen] ,
ADP[mitochondrial intermembrane space] ↔ ADP[cytosol] ,
L-alanine[extracellular space] + Na+[extracellular space] → L-alanine[cytosol] + Na+[cytosol] ,
citrate[mitochondrial intermembrane space] ↔ citrate[cytosol] ,
phosphate[mitochondrial lumen] + H+[mitochondrial lumen] → phosphate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] ,
GDP-L-fucose[cytosol] → GDP-L-fucose[golgi lumen] ,
L-alanine[extracellular space] + H+[extracellular space] → L-alanine[cytosol] + H+[cytosol] ,
L-serine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-serine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
L-glutamate[extracellular space] + Na+[extracellular space] → L-glutamate[cytosol] + Na+[cytosol] ,
ammonia[in] ↔ ammonia[out] ,
L-carnitine[mitochondrial intermembrane space] ↔ L-carnitine[cytosol] ,
myo-inositol[extracellular space] + H+[extracellular space]myo-inositol[cytosol] + H+[cytosol] ,
L-glutamate[in] + L-cystine[out] → L-cystine[in] + L-glutamate[out] ,
L-leucine[extracellular space] → L-leucine[cytosol] ,
glycine[extracellular space] + Na+[extracellular space] + H+[cytosol] → glycine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
Na+[extracellular space] + H+[cytosol] → Na+[cytosol] + H+[extracellular space] ,
2-oxoglutarate[mitochondrial intermembrane space] ↔ 2-oxoglutarate[cytosol] ,
pyruvate[mitochondrial intermembrane space] + H+[mitochondrial intermembrane space] → pyruvate[mitochondrial lumen] + H+[mitochondrial lumen] ,
chloride[extracellular space] + Na+[extracellular space] + glycine betaine[extracellular space] → chloride[cytosol] + Na+[cytosol] + glycine betaine[cytosol] ,
K+[out] → K+[in] ,
Na+[extracellular space] + L-threonine[extracellular space] → Na+[cytosol] + L-threonine[cytosol] ,
acetate[extracellular space] + H+[extracellular space] → acetate[cytosol] + H+[cytosol] ,
a neutral amino acid[extracellular space] + Na+[extracellular space] → a neutral amino acid[cytosol] + Na+[cytosol] ,
borate[extracellular space] + 2 Na+[extracellular space] → borate[cytosol] + 2 Na+[cytosol] ,
chloride[cytosol] → chloride[endosome lumen] ,
L-glutamate[mitochondrial intermembrane space] ↔ L-glutamate[cytosol] ,
Na+[extracellular space] + L-cysteine[extracellular space] → Na+[cytosol] + L-cysteine[cytosol] ,
Ca2+[cytosol] + Na+[extracellular space] ↔ Ca2+[extracellular space] + Na+[cytosol] ,
an O-acyl-L-carnitine[mitochondrial lumen] + L-carnitine[mitochondrial intermembrane space] → an O-acyl-L-carnitine[mitochondrial intermembrane space] + L-carnitine[mitochondrial lumen] ,
L-ascorbate[extracellular space] + 2 Na+[extracellular space] → L-ascorbate[cytosol] + 2 Na+[cytosol] ,
L-leucine[extracellular space] + Na+[extracellular space] → L-leucine[cytosol] + Na+[cytosol] ,
pyruvate[extracellular space] + H+[extracellular space] → pyruvate[cytosol] + H+[cytosol] ,
K+[extracellular space] ↔ K+[cytosol] ,
oxygen[in] ↔ oxygen[out] ,
glycine[extracellular space] + H+[extracellular space] → glycine[cytosol] + H+[cytosol] ,
chloride[nuclear lumen] → chloride[cytosol] ,
H2O[mitochondrial intermembrane space] ↔ H2O[cytosol] ,
L-methionine[extracellular space] + Na+[extracellular space] → L-methionine[cytosol] + Na+[cytosol] ,
dihydroxyacetone phosphate[mitochondrial intermembrane space] ↔ dihydroxyacetone phosphate[cytosol] ,
H2O[mitochondrial lumen] ↔ H2O[mitochondrial intermembrane space] ,
acetylcholine[cytosol] + H+[vesicle lumen] → acetylcholine[vesicle lumen] + H+[cytosol] ,
a neutral amino acid[extracellular space] + 2 Na+[cytosol] + chloride[cytosol] → a neutral amino acid[cytosol] + 2 Na+[cytosol] + chloride[cytosol] ,
L-proline[extracellular space] + H+[extracellular space] → L-proline[cytosol] + H+[cytosol] ,
L-glutamine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-glutamine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
(S)-1-pyrroline-5-carboxylate[in] ↔ (S)-1-pyrroline-5-carboxylate[out] ,
ADP[mitochondrial intermembrane space] + ATP[mitochondrial lumen] → ADP[mitochondrial lumen] + ATP[mitochondrial intermembrane space] ,
myo-inositol[extracellular space] + Na+[extracellular space]myo-inositol[cytosol] + Na+[cytosol] ,
L-arginine[extracellular space] → L-arginine[cytosol] ,
L-asparagine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-asparagine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
choline[extracellular space] + Na+[extracellular space] + chloride[extracellular space] → choline[cytosol] + Na+[cytosol] + chloride[cytosol] ,
oxaloacetate[mitochondrial intermembrane space] ↔ oxaloacetate[cytosol] ,
8 H+[in] → 8 H+[out] ,
Na+[extracellular space] + phosphate[extracellular space] → Na+[cytosol] + phosphate[cytosol] ,
K+[out] → K+[in] ,
L-phenylalanine[extracellular space] → L-phenylalanine[cytosol] ,
glycine[cytosol] → glycine[vesicle lumen] ,
2 hydrogen carbonate[extracellular space] + Na+[extracellular space] + chloride[cytosol] → 2 hydrogen carbonate[cytosol] + Na+[cytosol] + chloride[extracellular space] ,
Zn2+[extracellular space] → Zn2+[cytosol] ,
L-aspartate[mitochondrial intermembrane space] ↔ L-aspartate[cytosol] ,
D-serine[extracellular space] → D-serine[cytosol] ,
L-ornithine[cytosol] → L-ornithine[mitochondrial lumen] ,
L-isoleucine[extracellular space] + Na+[extracellular space] → L-isoleucine[cytosol] + Na+[cytosol] ,
acetoacetate[extracellular space] + H+[extracellular space] → acetoacetate[cytosol] + H+[cytosol] ,
chloride[extracellular space] + hydrogen carbonate[cytosol] → chloride[cytosol] + hydrogen carbonate[cytosol] ,
(S)-malate[mitochondrial lumen] + 2-oxoglutarate[mitochondrial intermembrane space] ↔ (S)-malate[mitochondrial intermembrane space] + 2-oxoglutarate[mitochondrial lumen] ,
L-glutamine[extracellular space] + L-arginine[cytosol] → L-glutamine[cytosol] + L-arginine[extracellular space] ,
a monocarboxylate[extracellular space] + H+[extracellular space] → a monocarboxylate[cytosol] + H+[cytosol] ,
Ca2+[mitochondrial intermembrane space] → Ca2+[mitochondrial lumen] ,
L-serine[extracellular space] + Na+[extracellular space] → L-serine[cytosol] + Na+[cytosol] ,
sn-glycerol 3-phosphate[mitochondrial intermembrane space]sn-glycerol 3-phosphate[cytosol] ,
H+[mitochondrial intermembrane space] ↔ H+[cytosol] ,
2 hydrogen carbonate[extracellular space] + Na+[extracellular space] → 2 hydrogen carbonate[cytosol] + Na+[cytosol] ,
Ca2+[extracellular space] + Li+[cytosol] → Ca2+[cytosol] + Li+[extracellular space] ,
glycine[extracellular space] + Na+[extracellular space] → glycine[cytosol] + Na+[cytosol] ,
L-histidine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-histidine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
citrate[mitochondrial lumen] + (S)-malate[mitochondrial intermembrane space] → citrate[mitochondrial intermembrane space] + (S)-malate[mitochondrial lumen] ,
ATP[mitochondrial intermembrane space] ↔ ATP[cytosol] ,
acetyl-CoA[cytosol] → acetyl-CoA[endoplasmic reticulum lumen] ,
2 H+[in] → 2 H+[out] ,
L-tryptophan[extracellular space] → L-tryptophan[cytosol] ,
L-alanine[extracellular space] + Na+[extracellular space] + H+[cytosol] → L-alanine[cytosol] + Na+[cytosol] + H+[extracellular space] ,
Ca2+[cytosol] + 4 Na+[extracellular space] + K+[cytosol] → Ca2+[extracellular space] + 4 Na+[cytosol] + K+[extracellular space] ,
4-imidazolone-5-propionate + H2O → formyl-L-isoglutamine ,
3,3',5-triiodothyronamine + an unknown reduced electron acceptor → 3,3'-diiodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
19-hydroxyandrostenedione + a reduced flavoprotein + oxygen → 19-oxoandrostenedione + an oxidized flavoprotein + 2 H2O ,
4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → 4α-carboxy-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
4-(3-pyridyl)-butanoate → 3-pyridylacetate ,
leucodopachrome + dopaquinone → L-dopachrome + L-dopa ,
4-coumaryl-CoA + coenzyme A + NAD+ + H2O → 4-hydroxybenzoyl-CoA + acetyl-CoA + NADH + H+ ,
N1-acetyl-N2-formyl-5-methoxykynuramine + H2O → N-acetyl-5-methoxykynurenamine + formate + H+ ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
L-serine → 2-aminoprop-2-enoate + H+ + H2O ,
3-hydroxy-N6,N6,N6-trimethyl-L-lysine → 4-trimethylammoniobutanal + glycine ,
4-(2-aminophenyl)-2,4-dioxobutanoate → kynurenate + H2O + H+ ,
pre-vitamin D3 + heat → vitamin D3 ,
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NAD(P)H + H+ → 2-dehydro-3-deoxy-D-gluconate + NAD(P)+ ,
L-erythro-5,6,7,8-tetrahydrobiopterin + NADP+ = 6-lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ ,
2 Fe2+ + 2 oxygen → 2 superoxide + 2 Fe3+ ,
(S)-2-amino-6-oxohexanoate ↔ (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + H2O + H+ ,
5,6-epoxy,18R-hydroxy-eicosapentaenoate + H2O = resolvin E1 ,
4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + NAD(P)H + H+ + oxygen = 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)+ + 2 H2O ,
4,4-dimethyl-5α-cholest-7-en-3β-ol + NAD(P)H + oxygen + H+ = 4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + NAD(P)+ + H2O ,
2 monodehydroascorbate radical → L-ascorbate + L-dehydro-ascorbate + H+ ,
(R)-lactaldehyde + NAD+ + H2O → (R)-lactate + NADH + 2 H+ ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
4-oxo-4-(3-pyridyl)-butanoate + 2 H+ → 4-hydroxy-4-(3-pyridyl)-butanoate ,
3-iodo-L-tyrosine + NADPH → L-tyrosine + iodide + NADP+ ,
sphingosine 1-phosphate + H2O → sphingosine + phosphate ,
5-methoxyindoleacetaldehyde + an unknown oxidized electron acceptor + H2O → 5-methoxyindole acetate + an unknown reduced electron acceptor ,
L-threonine = (2Z)-2-aminobut-2-enoate + H2O + H+ ,
keto-L-sorbose ↔ L-sorbopyranose ,
glycine + a tetrahydrofolate + NAD+ → a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH ,
3,4-dihydroxyphenylpyruvate + H+ → 3,4-dihydroxyphenylacetaldehyde + CO2 ,
NADP+ = 2'-phospho-cyclic ADP-ribose + nicotinamide ,
[thyroglobulin]-L-thyroxine + H2O → L-thyroxine + [unspecified degradation products] ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + an unknown reduced electron acceptor + oxygen → 18R-hydroxy-eicosapentaenoate + an unknown oxidized electron acceptor + H2O ,
2-oxoadipate + coenzyme A + NAD+ → CO2 + glutaryl-CoA + NADH ,
ribose-1-arsenate + dihydrolipoate + H+ → D-ribofuranose + arsenite + (R)-lipoate ,
3,5,3'-triiodo-L-thyronine + an unknown reduced electron acceptor → 3,5-diiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADPH + oxygen → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + NADP+ + H2O ,
4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + 2 H2O ,
pyruvate + hydroxylamine → pyruvic oxime + H2O ,
4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → 4α-carboxy-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
cotinine → cotinine N-oxide ,
5,6-dihydroxyindole + 2 H+ + oxygen → indole-5,6-quinone + 2 H2O ,
4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADP+ + 2 H2O ,
sphingosine + ATP → sphingosine 1-phosphate + ADP + H+ ,
D-arabinofuranose ↔ D-arabinopyranose ,
aldehydo-D-mannose → β-D-mannose ,
3-O-methyldopa + 2-oxoglutarate + H+ ↔ 3-methoxy-4-hydroxyphenylpyruvate + L-glutamate ,
L-homoserine → (2Z)-2-aminobut-2-enoate + H+ + H2O ,
di-trans, poly-cis-polyprenyl diphosphate (C80) + H2O → di-trans, poly-cis-polyprenol (C80) + diphosphate ,
stearidonoyl-CoA + malonyl-CoA + 2 NADPH + 3 H+ = eicosatetraenoyl-CoA + CO2 + coenzyme A + 2 NADP+ + H2O ,
S-adenosyl-L-methionine + an N-terminal-PPK-[protein] → S-adenosyl-L-homocysteine + an N terminal N-methyl-PPK-[protein] + H+ ,
S-adenosyl-L-methionine + an N-terminal-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N-methyl-(A/S)PK-[protein] + H+ ,
(25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADPH + oxygen + H+ → (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADP+ + 2 H2O ,
neopinone → codeinone ,
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 an unknown reduced electron acceptor + 2 oxygen → 17S-hydro(p)docosahexaenoate + 2 an unknown oxidized electron acceptor + 2 H2O ,
arachidonate + oxygen → (5S)-HPETE ,
15S-hydroxypentaenoate + oxygen → lipoxin A4 ,
(12Z,15Z)-9,10-epoxyoctadeca-12,15-dienoate + H2O = (12Z,15Z)-9,10-dihydroxyoctadeca-12,15-dienoate ,
2-oxoadipate + ammonium + NAD+ ← 2-aminomuconate + NADH + H2O + 2 H+ ,
3,5-diiodothyronamine + an unknown reduced electron acceptor → 3-iodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
3-monoiodothyronine + an unknown reduced electron acceptor → L-thyronine + iodide + an unknown oxidized electron acceptor + H+ ,
cis-aconitate + H2O → D-threo-isocitrate ,
14-oxolanosterol + NADPH + oxygen → 14-demethyllanosterol + formate + NADP+ + H2O ,
ethanol + NADPH + oxygen + H+ → acetaldehyde + NADP+ + 2 H2O ,
norcotinine → 4-oxo-4-(3-pyridyl)-butanamide ,
an L-cysteine-S-conjugate = a thiol + 2-aminoprop-2-enoate + H+ ,
an Fe(II)-siderophore + H+ → a siderophore + Fe2+ ,
(3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H2O + H+ ↔ L-4-hydroxyglutamate semialdehyde ,
(S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + NAD(P)+ + 2 H2O = L-2-aminoadipate + NAD(P)H + H+ ,
a 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one → a 3-isopropenyl-6-oxoheptanoate + H+ ,
(25R)-3α,7α-dihydroxy-5β-cholestan-26-al + NADPH + oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + NADP+ + H2O ,
3,5,3'-triiodo-L-thyronine → thyronamine ,
β-carotene 15,15' epoxide + H2O = 15,15'-dihydroxy-β-carotene ,
2-amino-3-oxobutanoate + 2 H+ → aminoacetone + CO2 ,
2-carboxy-L-xylonolactone + H2O → 2-carboxy-L-threo-pentonate + H+ ,
7-O-acetylsalutaridinol → thebaine + acetate + H+ ,
2 L-cysteine → lanthionine + hydrogen sulfide ,
prephytoene diphosphate = all-trans-phytoene + diphosphate ,
(15R)-hydroxyeicosapentaenoate + oxygen → 15 epi-lipoxin A4 ,
3-iodothyronamine + an unknown reduced electron acceptor → thyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
19-oxo-testosterone + a reduced flavoprotein + oxygen → 17β-estradiol + formate + an oxidized flavoprotein + H2O + H+ ,
aminocarboxymuconate semialdehyde → quinolinate + H2O ,
bupropion → 3-chlorobenzoate ,
4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + 2 H2O ,
a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a diphthine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
a 2-monoglyceride → a 1-monoglyceride ,
L-thyroxine → tetraiodothyroacetate ,
a [deoxyhypusine synthase]-N-(4-aminobutylidene)-lysine + an [eIF5A-precursor]-lysine = an [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + a [deoxyhypusine synthase]-L-lysine + H+ ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
2 geranylgeranyl diphosphate = prephytoene diphosphate + diphosphate ,
formyl-L-isoglutamine + H2O → L-isoglutamine + formate ,
3,3',5'-triiodothyronamine + an unknown reduced electron acceptor → 3,3'-diiodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
1-(3-aminopropyl)-4-aminobutanal → 1-(3-aminopropyl)-pyrrolinium + H2O ,
19-oxoandrostenedione + a reduced flavoprotein + oxygen → estrone + formate + an oxidized flavoprotein + H2O + H+ ,
a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-carboxy-3-(methylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
13'-hydroxy-α-tocopherol → 5'-α-carboxylmethylbutylhydroxychroman ,
D-altropyranose ↔ aldehydo-D-altrose ,
an [L-cysteine desulfurase] L-cysteine persulfide + a ThiI sulfur-carrier protein = an [L-cysteine desulfurase]-L-cysteine + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
(S)-1-pyrroline-5-carboxylate[mitochondrial lumen] + NAD+[mitochondrial lumen] + 2 H2O[mitochondrial lumen] → L-glutamate[mitochondrial lumen] + NADH[mitochondrial lumen] + H+[mitochondrial lumen] ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
glutathione + intracellular S0 → S-sulfanylglutathione ,
L-lysine + 2-oxoglutarate → 2-keto-6-aminocaproate + L-glutamate ,
ammeline + H2O = ammelide + ammonium ,
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 an unknown reduced electron acceptor + 2 oxygen → 17-hydro(p)docosahexaenoate + 2 an unknown oxidized electron acceptor + 2 H2O ,
3,3',5,5'-tetraiodothyronamine + an unknown reduced electron acceptor → 3,3',5-triiodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
4α-methyl-zymosterol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
4-hydroxy-4-(3-pyridyl)-butanoate → 4-(3-pyridyl)-3-butenoate ,
3,5-diiodo-L-tyrosine + NADPH + H+ → 3-iodo-L-tyrosine + iodide + NADP+ ,
5-methoxyindoleacetaldehyde + an unknown reduced electron acceptor → 5-methoxytryptophol + an unknown oxidized electron acceptor ,
α-D-ribose 5-phosphate → β-D-ribose 5-phosphate ,
L-dehydro-ascorbate + NADPH → L-ascorbate + NADP+ ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
dATP + hydroxyl radical → 2-hydroxy-dATP + H+ ,
dopamine + 3,4-dihydroxyphenylacetaldehyde → S-norlaudanosoline + H2O ,
2'-phospho-cyclic ADP-ribose + nicotinate = nicotinate-adenine dinucleotide phosphate ,
2 indoxyl + oxygen → indigo + 2 H2O ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
(S)-propane-1,2-diol + NAD+ ← acetol + NADH + H+ ,
2-oxo-4-methylthiobutanoate + hydroxyl radical → ethylene + methanethiol + 2 CO2 ,
18R-hydroxy-eicosapentaenoate + oxygen → 5S hydro(peroxy),18R-hydroxy-eicosapentaenoate ,
betaine aldehyde hydrate ↔ betaine aldehyde + H2O ,
4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
2 L-ascorbate + hydrogen peroxide + 2 H+ → 2 monodehydroascorbate radical + 2 H2O ,
cotinine → cotinine methonium ion ,
5,6-dihydroxyindole-2-carboxylate + 2 H+ + oxygen → indole-5,6-quinone-2-carboxylate + 2 H2O ,
4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADPH + oxygen → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate + NADP+ + H2O ,
sphinganine + a long-chain acyl-CoA → a dihydroceramide + coenzyme A + H+ ,
melatonin + H2O → 5-methoxytryptamine + acetate + H+ ,
aldehydo-L-arabinose ↔ L-arabinopyranose ,
aldehydo-D-xylose ↔ a D-xylopyranose ,
3-methoxy-4-hydroxyphenylpyruvate + NADH + H+ ↔ 3-methoxy-4-hydroxyphenyllactate + NAD+ ,
(R)-methylmalonate-semialdehyde ↔ (S)-methylmalonate-semialdehyde ,
di-trans, poly-cis-polyprenol (C80) + NADPH + H+ → a dolichol + NADP+ ,
NAD+ = cyclic ADP-ribose + nicotinamide ,
(24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA + NAD+ → 3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA + NADH + H+ ,
S-adenosyl-L-methionine + an N terminal N-methyl-PPK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-PPK-[protein] + H+ ,
2-oxoglutarate[mitochondrial lumen] + coenzyme A[mitochondrial lumen] + NAD+[mitochondrial lumen] → succinyl-CoA[mitochondrial lumen] + CO2[mitochondrial lumen] + NADH[mitochondrial lumen] ,
S-adenosyl-L-methionine + an N terminal N-methyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N-dimethyl-(A/S)PK-[protein] + H+ ,
geranial ↔ neral ,
NADH + H2O → (S)-NADHX ,
5β-cholestane-3α,7α,12α-triol + NADPH + oxygen + H+ → (25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADP+ + H2O ,
dopaquinone → leucodopachrome + H+ ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate ,
17S-hydro(p)docosahexaenoate + an unknown reduced electron acceptor + oxygen → 7S-hydroperoxy,17S-H-docosahexaenoate + an unknown oxidized electron acceptor + H2O ,
(9Z,15Z)-12,13-epoxy-octadeca-9,15-dienoate + H2O = (9Z,15Z)-12,13-dihydroxyoctadeca-9,15-dienoate ,
3,3',5'-triiodothyronamine + an unknown reduced electron acceptor → 3',5'-diiodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
cacodylate + 3 H+ → dimethylarsinous acid + H2O ,
3,3'-diiodothyronine + an unknown reduced electron acceptor → 3'-monoiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
L-tyrosine + 0.5 oxygen → L-dopa ,
4α-methyl-cholesta-8-enol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
5'-hydroxycotinine → 4-oxo-4-(3-pyridyl)-N-methylbutanamide ,
4-oxo-4-(3-pyridyl)-butanamide → 4-oxo-4-(3-pyridyl)-butanoate ,
a dihydroceramide + NAD(P)H + oxygen + H+ → a sphingosine ceramide + NAD(P)+ + 2 H2O ,
L-lyxopyranose → aldehydo-L-lyxose ,
D-myo-inositol (1,3,4,6)-tetrakisphosphate = D-myo-inositol (1,3,4,5)-tetrakisphosphate ,
D-galactopyranuronate ↔ aldehydo-D-galacturonate ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
(1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate → (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
15,15'-dihydroxy-β-carotene + an unknown oxidized electron acceptor = 2 all-trans-retinal + an unknown reduced electron acceptor ,
cyclic-2,3-O-oxalyl-L-threonate → cyclic- 3,4-O-oxalyl-L-threonate ,
(15R)-hydroxyeicosapentaenoate + oxygen → 15 epi-lipoxin B4 ,
vernolate + H2O = (9Z)-12,13-dihydroxyoctadeca-9-enoate ,
3'-iodothyronamine + an unknown reduced electron acceptor → thyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
ammonia + H+ ↔ ammonium ,
lanosterol + NADPH + H+ + oxygen → 14-hydroxylanosterol + NADP+ + H2O ,
formaldehyde + a tetrahydrofolate → a 5,10-methylene-tetrahydrofolate + H2O ,
3-chlorobenzoate + glycine → m-chlorohippurate + H2O ,
a 2-[(3S)-3-carboxy-3-(methylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine → a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H+ ,
(S)-nicotine + H2O → nornicotine + formaldehyde + 2 H+ ,
XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+ ,
adenine + hydroxyl radical → isoguanine + H+ ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+ ↔ (E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein ,
2 L-homocysteine → hydrogen sulfide + L-homolanthionine ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
sulfite + 2 Fe3+ + H2O = sulfate + 2 Fe2+ + 2 H+ ,
5β-cholestane-3α,7α-diol + NADPH + H+ + oxygen → (25R)-5β-cholestane-3α,7α,26-triol + NADP+ + H2O ,
3,5,3'-triiodo-L-thyronine → 3,3',5-triiodothyroacetate ,
an [eIF5A-precursor]-N-(4-aminobutylidene)-lysine + NADH + H+ = an [eIF5A-precursor]-deoxyhypusine + NAD+ ,
2 L-dehydro-ascorbate + oxygen → 2 cyclic-2,3-O-oxalyl-L-threonate + 2 H+ ,
a [protein] N6,N6-dimethyl-L-lysine + 2-oxoglutarate + oxygen = a [protein] N6-methyl-L-lysine + succinate + formaldehyde + CO2 ,
prephytoene diphosphate = 15-cis-phytoene + diphosphate ,
a CDP-diacylglycerol + an L-1-phosphatidyl-glycerol → a cardiolipin + CMP + H+ ,
2-oxobutanoate + coenzyme A + NAD+ → propanoyl-CoA + CO2 + NADH ,
4-imidazolone-5-propionate + oxygen + H2O + 2 H+ → 4-oxoglutaramate + ammonium + formate ,
3,3'-diiodothyronamine + an unknown reduced electron acceptor → 3-iodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
1-(3-aminopropyl)-pyrrolinium → 1,5-diazabicyclononane + H+ ,
testosterone + a reduced flavoprotein + oxygen → 19-hydroxytestosterone + an oxidized flavoprotein + H2O ,
a 2(R)-hydroperoxy fatty acid + H+ → a fatty aldehyde + CO2 + H2O ,
bupropion + 2 H+ = threohydrobupropion ,
2'-hydroxynicotine → pseudooxynicotine ,
5'-α-carboxylmethylbutylhydroxychroman → α-carboxyethylhydroxychroman ,
L-cystine = 2-aminoprop-2-enoate + thiocysteine + H+ ,
aldehydo-D-ribose ↔ D-ribofuranose ,
4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate → xanthurenate + H+ + H2O ,
2 L-arginine + 2 NADPH + 2 H+ + 2 oxygen = 2 Nω-hydroxy-L-arginine + 2 NADP+ + 2 H2O ,
spermidine + NAD+ = dehydrospermidine + NADH + H+ ,
dehydroascorbate (bicyclic form) → 2,3-dioxo-L-gulonate + H+ ,
2-aminoprop-2-enoate + H+ + H2O → pyruvate + ammonium ,
2-keto-6-aminocaproate + hydrogen peroxide → 5-aminopentanoate + CO2 + H2O ,
17-hydro(p)docosahexaenoate + an unknown oxidized electron acceptor + H2O → 7S-hydroperoxy,17R-H-docosahexaenoate + an unknown reduced electron acceptor ,
3,3',5,5'-tetraiodothyronamine + an unknown reduced electron acceptor → 3,3',5'-triiodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
androst-4-ene-3,17-dione + a reduced flavoprotein + oxygen → 19-hydroxyandrostenedione + an oxidized flavoprotein + H2O ,
4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + 2 H2O ,
n melanochrome → eumelanin ,
4-(3-pyridyl)-3-butenoate + 2 H+ → 4-(3-pyridyl)-butanoate ,
3-(4-hydroxyphenyl)lactate → 4-coumarate + H2O ,
melatonin + hydrogen peroxide → N1-acetyl-N2-formyl-5-methoxykynuramine + 2 H+ ,
β-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
L-ascorbate + an unknown oxidized electron acceptor + 2 H+ → monodehydroascorbate radical + an unknown reduced electron acceptor ,
2-aminoprop-2-enoate → 2-iminopropanoate ,
aldehydo-L-fucose ↔ L-fucopyranose ,
ATP + UTP + ammonium → ADP + CTP + phosphate + 2 H+ ,
S-norlaudanosoline + 3 S-adenosyl-L-methionine → (S)-reticuline + 3 S-adenosyl-L-homocysteine + 3 H+ ,
7-dehydrocholesterol + UV light → pre-vitamin D3 ,
hydrogen peroxide + Fe2+ → hydroxyl radical + Fe3+ + OH- ,
2-keto-6-aminocaproate → Δ1-piperideine-2-carboxylate + H+ + H2O ,
L-cysteine + L-homocysteine → L-cystathionine + hydrogen sulfide ,
5S hydro(peroxy),18R-hydroxy-eicosapentaenoate → resolvin E1 ,
3,3',5'-triiodo-L-thyronine + an unknown reduced electron acceptor → 3',5'-diiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)H + oxygen = 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate + NAD(P)+ + H2O ,
indole-5,6-quinone + indole-5,6-quinone-2-carboxylate → melanochrome ,
2-oxoglutaramate → 2-hydroxy-5-oxoproline ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
L-arabinofuranose ↔ L-arabinopyranose ,
keto-D-fructose → β-D-fructofuranose ,
3-methoxy-4-hydroxyphenylpyruvate → homovanillate ,
tyramine → dopamine ,
5-hydroxyindole acetaldehyde + L-cysteine ↔ 5-hydroxyindole thiazolidine carboxylate + H2O ,
cyclic ADP-ribose + H2O = ADP-D-ribose + H+ ,
(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA + NAD+ → 3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA + NADH + H+ ,
[thyroglobulin]-triiodothyronine + H2O → 3,5,3'-triiodo-L-thyronine + [unspecified degradation products] ,
NADH + H2O → (R)-NADHX ,
5S hydro(peroxy),18R-hydroxy-eicosapentaenoate + an unknown reduced electron acceptor → resolvin E2 + an unknown oxidized electron acceptor + H2O ,
17S-hydro(p)docosahexaenoate + an unknown reduced electron acceptor + oxygen → 4S-hydroperoxy,17S-H-docosahexaenoate + an unknown oxidized electron acceptor + H2O ,
15S-hydroxypentaenoate + oxygen → lipoxin B4 ,
L-rhamnopyranose ↔ L-rhamnofuranose ,
3',5'-diiodothyronamine + an unknown reduced electron acceptor → 3'-iodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
3'-monoiodothyronine + an unknown reduced electron acceptor → L-thyronine + iodide + an unknown oxidized electron acceptor + H+ ,
4,4-dimethylzymosterol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+ + H2O ,
4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen + H+ → 4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + 2 H2O ,
4-oxo-4-(3-pyridyl)-N-methylbutanamide → 4-oxo-4-(3-pyridyl)-butanoate ,
L-dopachrome + H+ → 5,6-dihydroxyindole + CO2 ,
24,25-dihydrolanosterol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADP+ + H2O ,
α-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
D-arabinopyranose → aldehydo-D-arabinose ,
aldehydo-D-mannose → D-mannopyranose ,
L-cystathionine → (2Z)-2-aminobut-2-enoate + L-cysteine + H+ ,
(25S)-3α,7α-dihydroxy-5β-cholestanoyl-CoA + an unknown oxidized electron acceptor → (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA + an unknown reduced electron acceptor ,
S-adenosyl-L-methionine + an N terminal N,N-dimethyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein] + H+ ,
arachidonate + an unknown reduced electron acceptor + oxygen → 15S-hydroxypentaenoate + an unknown oxidized electron acceptor + H2O ,
(9Z,12Z)-15,16-epoxyoctadeca-9,12-dienoate + H2O = (9Z,12Z)-15,16-dihydroxyoctadeca-9,12-dienoate ,
3,3',5-triiodothyronamine + an unknown reduced electron acceptor → 3,5-diiodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
3,3'-diiodothyronine + an unknown reduced electron acceptor → 3-monoiodothyronine + iodide + an unknown oxidized electron acceptor + H+ ,
simvastatin lactone + H2O → simvastatin acid + H+ ,
citrate[mitochondrial lumen]cis-aconitate[mitochondrial lumen] + H2O[mitochondrial lumen] ,
14-hydroxylanosterol + NADPH + H+ + oxygen → 14-oxolanosterol + NADP+ + 2 H2O ,
nornicotine + H2O → norcotinine + 5 H+ ,
an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + an [N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine → an [E1 ubiquitin-activating enzyme]-L-cysteine + an S-ubiquitinyl-[an N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine ,
2'-deoxyadenosine + hydroxyl radical → 2-hydroxydeoxyadenosine + H+ ,
D-glucopyranuronate ↔ aldehydo-D-glucuronate ,
aldehydo-D-glucose → D-glucopyranose ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
(25R)-5β-cholestane-3α,7α,26-triol + NADPH + H+ + oxygen → (25R)-3α,7α-dihydroxy-5β-cholestan-26-al + NADP+ + 2 H2O ,
L-thyroxine = 3-iodothyronamine ,
all-trans-β-carotene + an unknown reduced electron acceptor + oxygen = β-carotene 15,15' epoxide + an unknown oxidized electron acceptor + H2O ,
2,3-dioxo-L-gulonate → 2-carboxy-L-xylonolactone ,
(S)-reticuline → 1,2-dehydroreticulinium + 2 H+ ,
17-hydro(p)docosahexaenoate + an unknown oxidized electron acceptor + H2O → 4S-hydroperoxy,17R-H-docosahexaenoate + an unknown reduced electron acceptor ,
arachidonate + NADPH + oxygen + H+ → (15R)-hydroxyeicosapentaenoate + NADP+ + H2O ,
4-oxoglutaramate + H2O → 2-oxoglutarate + ammonium ,
3,3'-diiodothyronamine + an unknown reduced electron acceptor → 3'-iodothyronamine + iodide + an unknown oxidized electron acceptor + H+ ,
19-hydroxytestosterone + a reduced flavoprotein + oxygen → 19-oxo-testosterone + an oxidized flavoprotein + 2 H2O ,
intracellular S0n + a thiol → intracellular S0n-1 + a perthiol ,
squalene + NAD(P)+ + diphosphate = presqualene diphosphate + NAD(P)H + H+ ,
3-oxo-3-phenylpropanoyl-CoA + coenzyme A = benzoyl-CoA + acetyl-CoA ,
bupropion + 2 H+ = erythrohydrobupropion ,
4,4-dimethyl-5α-cholesta-8-en-3-β-ol + NAD(P)H + oxygen + H+ → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+ + H2O ,
CTP + hydroxyl radical → 5-hydroxy-CTP + H+ ,
L-cysteine = 2-aminoprop-2-enoate + hydrogen sulfide + H+ ,
5-phospho-α-D-ribose 1-diphosphate + H2O = α-D-ribose 1,5-bisphosphate + phosphate + H+ ,
aldehydo-D-ribose ↔ D-ribopyranose ,
2-aminomuconate 6-semialdehyde → picolinate + H2O ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
2 Nω-hydroxy-L-arginine + NADPH + 2 oxygen = 2 L-citrulline + 2 nitric oxide + NADP+ + 2 H2O + H+ ,
dehydrospermidine + a [deoxyhypusine synthase]-L-lysine = a [deoxyhypusine synthase]-N-(4-aminobutylidene)-lysine + propane-1,3-diamine ,
L-dehydro-ascorbate + H2O → dehydroascorbate (bicyclic form) ,
(5S)-HPETE → leukotriene A4 + H2O ,
sulfite + H+ ↔ bisulfite ,
5,6-epoxy,18R-hydroxy-eicosapentaenoate + 2 H+ = resolvin E2


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Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
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