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Homo sapiens Enzyme: Histone-lysine N-methyltransferase SETD1A

Gene: SETD1A Accession Number: HS01894 (HumanCyc)

Synonyms: KIAA0339, KMT2F, SET1, SET1A, hSET1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, Set1/Ash2 histone methyltransferase complex subunit SET1

Map Position: [31,465,647 -> 31,493,017] (34.5 centisomes) on Chromosome 16
Length: 27371 bp

Unification Links: Ensembl:ENSG00000099381 , Entrez:BAA20797 , MOPED:O15047 , UniProt:O15047

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

GO Terms:

Molecular Function: GO:0003676 - nucleic acid binding


Enzymatic reaction of: Histone-lysine N-methyltransferase SETD1A

EC Number: 2.1.1.43

a [histone]-L-lysine + S-adenosyl-L-methionine <=> a [histone] N6-methyl-L-lysine + S-adenosyl-L-homocysteine + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.


Gene Local Context (not to scale): ?

Gene local context diagram

Exons/Introns:

Schematic showing introns, exons and/or isoforms of SETD1A


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
Page generated by SRI International Pathway Tools version 19.0 on Sun Aug 30, 2015, biocyc13.