|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: [myelin basic protein]-arginine N-methyltransferase
Enzyme Commission Synonyms: myelin basic protein methylase I, protein methylase I, S-adenosyl-L-methionine:[myelin-basic-protein]-arginine ω-N-methyltransferase
Enzyme Commission Summary:
Forms the omega-N-monomethyl-, omega-N,omega-N-dimethyl- and omega N,omega'-N-dimethyl-arginine derivatives. The name protein methylase I is misleading since it has been used for a number of enzymes with different specificities. Formerly EC 126.96.36.199.
Ghosh88: Ghosh SK, Paik WK, Kim S (1988). "Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein- and histone-specific enzyme." J Biol Chem 263(35);19024-33. PMID: 2461933
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