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MetaCyc Compound Class: a bile acid

Superclasses: a steroid

Summary:
Bile acids are steroid acids found predominantly in the bile of mammals. They are produced in the liver by the oxidation of cholesterol, are stored in gall bladder, and secreted into the intestine in the form of salts, where they assist with the absorption and digestion of lipids. About half of the cholesterol produced in the body is used for bile acid synthesis.

Child Classes: muricholate (2)

Instances:
3 β-hydroxy-7,12-diketocholanate,
3,7,12-trioxo-5β-cholanate,
3-dehydrocholate,
6-β-hydroxylithocholate,
allocholate,
chenodeoxycholate,
cholate,
deoxycholate,
glycochenodeoxycholate,
glycochenodeoxycholate 7-sulfate,
glycocholate,
glycodeoxycholate,
glycolithocholate,
glycolithocholate-3-sulfate,
hyodeoxycholate,
isocholate,
lithocholate,
taurochenodeoxycholate,
taurocholate,
taurodeoxycholate,
taurohyocholate,
taurolithocholate,
taurolithocholate sulfate

Unification Links: ChEBI:3098

Reactions known to consume the compound:

Not in pathways:
a steroid + 2 a reduced adrenodoxin + oxygen + 2 H+ → an 11-β-hydroxysteroid + 2 an oxidized adrenodoxin + H2O


References

Chiang08: Chiang YR, Ismail W, Heintz D, Schaeffer C, Van Dorsselaer A, Fuchs G (2008). "Study of anoxic and oxic cholesterol metabolism by Sterolibacterium denitrificans." J Bacteriol 190(3);905-14. PMID: 18039763


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Thu Feb 11, 2016, biocyc14.