Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc EC 1.14.13 -- With NADH or NADPH as one donor, and incorporation of one atom of oxygen

Parent Class: EC-Numbers 1 -- Oxidoreductases 1.14 -- Acting on paired donors, with incorporation or reduction of molecular oxygen

Instances:
1.14.13.1 -- salicylate 1-monooxygenase ,
1.14.13.2 -- 4-hydroxybenzoate 3-monooxygenase ,
1.14.13.4 -- melilotate 3-monooxygenase ,
1.14.13.5 -- imidazoleacetate 4-monooxygenase ,
1.14.13.6 -- orcinol 2-monooxygenase ,
1.14.13.7 -- phenol 2-monooxygenase ,
1.14.13.8 -- flavin-containing monooxygenase ,
1.14.13.9 -- kynurenine 3-monooxygenase ,
1.14.13.10 -- 2,6-dihydroxypyridine 3-monooxygenase ,
1.14.13.11 -- trans-cinnamate 4-monooxygenase ,
1.14.13.12 -- benzoate 4-monooxygenase ,
1.14.13.13 -- calcidiol 1-monooxygenase ,
1.14.13.14 -- trans-cinnamate 2-monooxygenase ,
1.14.13.15 -- cholestanetriol 26-monooxygenase ,
1.14.13.16 -- cyclopentanone monooxygenase ,
1.14.13.17 -- cholesterol 7α-monooxygenase ,
1.14.13.18 -- 4-hydroxyphenylacetate 1-monooxygenase ,
1.14.13.19 -- taxifolin 8-monooxygenase ,
1.14.13.20 -- 2,4-dichlorophenol 6-monooxygenase ,
1.14.13.21 -- flavonoid 3′-monooxygenase ,
1.14.13.22 -- cyclohexanone monooxygenase ,
1.14.13.23 -- 3-hydroxybenzoate 4-monooxygenase ,
1.14.13.24 -- 3-hydroxybenzoate 6-monooxygenase ,
1.14.13.25 -- methane monooxygenase (soluble) ,
1.14.13.26 -- phosphatidylcholine 12-monooxygenase ,
1.14.13.27 -- 4-aminobenzoate 1-monooxygenase ,
1.14.13.28 -- 3,9-dihydroxypterocarpan 6a-monooxygenase ,
1.14.13.29 -- 4-nitrophenol 2-monooxygenase ,
1.14.13.30 -- leukotriene-B4 20-monooxygenase ,
1.14.13.31 -- 2-nitrophenol 2-monooxygenase ,
1.14.13.32 -- albendazole monooxygenase ,
1.14.13.33 -- 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] ,
1.14.13.34 -- leukotriene-E4 20-monooxygenase ,
1.14.13.35 -- anthranilate 3-monooxygenase (deaminating) ,
1.14.13.36 -- 5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase ,
1.14.13.37 -- methyltetrahydroprotoberberine 14-monooxygenase ,
1.14.13.38 -- anhydrotetracycline monooxygenase ,
1.14.13.39 -- nitric-oxide synthase (NADPH dependent) ,
1.14.13.40 -- anthraniloyl-CoA monooxygenase ,
1.14.13.41 -- tyrosine N-monooxygenase ,
1.14.13.43 -- questin monooxygenase ,
1.14.13.44 -- 2-hydroxybiphenyl 3-monooxygenase ,
1.14.13.46 -- (-)-menthol monooxygenase ,
1.14.13.47 -- (S)-limonene 3-monooxygenase ,
1.14.13.48 -- (S)-limonene 6-monooxygenase ,
1.14.13.49 -- (S)-limonene 7-monooxygenase ,
1.14.13.50 -- pentachlorophenol monooxygenase ,
1.14.13.51 -- 6-oxocineole dehydrogenase ,
1.14.13.52 -- isoflavone 3′-hydroxylase ,
1.14.13.53 -- 4′-methoxyisoflavone 2′-hydroxylase ,
1.14.13.54 -- ketosteroid monooxygenase ,
1.14.13.55 -- protopine 6-monooxygenase ,
1.14.13.56 -- dihydrosanguinarine 10-monooxygenase ,
1.14.13.57 -- dihydrochelirubine 12-monooxygenase ,
1.14.13.58 -- benzoyl-CoA 3-monooxygenase ,
1.14.13.59 -- L-lysine N6-monooxygenase (NADPH) ,
1.14.13.61 -- 2-hydroxyquinoline 8-monooxygenase ,
1.14.13.62 -- 4-hydroxyquinoline 3-monooxygenase ,
1.14.13.63 -- 3-hydroxyphenylacetate 6-hydroxylase ,
1.14.13.64 -- 4-hydroxybenzoate 1-hydroxylase ,
1.14.13.66 -- 2-hydroxycyclohexanone 2-monooxygenase ,
1.14.13.67 -- quinine 3-monooxygenase ,
1.14.13.68 -- 4-hydroxyphenylacetaldehyde oxime monooxygenase ,
1.14.13.69 -- alkene monooxygenase ,
1.14.13.70 -- sterol 14α-demethylase ,
1.14.13.71 -- N-methylcoclaurine 3′-monooxygenase ,
1.14.13.72 -- methylsterol monooxygenase ,
1.14.13.73 -- tabersonine 16-hydroxylase ,
1.14.13.74 -- 7-deoxyloganin 7-hydroxylase ,
1.14.13.75 -- vinorine hydroxylase ,
1.14.13.76 -- taxane 10β-hydroxylase ,
1.14.13.77 -- taxane 13α-hydroxylase ,
1.14.13.78 -- ent-kaurene oxidase ,
1.14.13.79 -- ent-kaurenoic acid oxidase ,
1.14.13.80 -- (R)-limonene 6-monooxygenase ,
1.14.13.81 -- magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase ,
1.14.13.82 -- vanillate monooxygenase ,
1.14.13.83 -- precorrin-3B synthase ,
1.14.13.84 -- 4-hydroxyacetophenone monooxygenase ,
1.14.13.85 -- glyceollin synthase ,
1.14.13.86 -- 2-hydroxyisoflavanone synthase ,
1.14.13.87 -- licodione synthase ,
1.14.13.88 -- flavanoid 3′,5′-hydroxylase ,
1.14.13.89 -- isoflavone 2′-hydroxylase ,
1.14.13.90 -- zeaxanthin epoxidase ,
1.14.13.91 -- deoxysarpagine hydroxylase ,
1.14.13.92 -- phenylacetone monooxygenase ,
1.14.13.93 -- (+)-abscisic acid 8′-hydroxylase ,
1.14.13.94 -- lithocholate 6β-hydroxylase ,
1.14.13.95 -- 7α-hydroxycholest-4-en-3-one 12α-hydroxylase ,
1.14.13.96 -- 5β-cholestane-3α,7α-diol 12α-hydroxylase ,
1.14.13.97 -- taurochenodeoxycholate 6α-hydroxylase ,
1.14.13.98 -- cholesterol 24-hydroxylase ,
1.14.13.99 -- 24-hydroxycholesterol 7α-hydroxylase ,
1.14.13.100 -- 25/26-hydroxycholesterol 7α-hydroxylase ,
1.14.13.101 -- senecionine N-oxygenase ,
1.14.13.102 -- psoralen synthase ,
1.14.13.103 -- 8-dimethylallylnaringenin 2′-hydroxylase ,
1.14.13.104 -- (+)-menthofuran synthase ,
1.14.13.105 -- monocyclic monoterpene ketone monooxygenase ,
1.14.13.106 -- epi-isozizaene 5-monooxygenase ,
1.14.13.107 -- limonene 1,2-monooxygenase ,
1.14.13.108 -- abieta-7,13-diene hydroxylase ,
1.14.13.109 -- abieta-7,13-dien-18-ol hydroxylase ,
1.14.13.110 -- geranylgeraniol 18-hydroxylase ,
1.14.13.111 -- methanesulfonate monooxygenase ,
1.14.13.112 -- 3-epi-6-deoxocathasterone 23-monooxygenase ,
1.14.13.113 -- FAD-dependent urate hydroxylase ,
1.14.13.114 -- 6-hydroxynicotinate 3-monooxygenase ,
1.14.13.115 -- angelicin synthase ,
1.14.13.116 -- geranylhydroquinone 3′′-hydroxylase ,
1.14.13.117 -- isoleucine N-monooxygenase ,
1.14.13.118 -- valine N-monooxygenase ,
1.14.13.119 -- 5-epiaristolochene 1,3-dihydroxylase ,
1.14.13.120 -- costunolide synthase ,
1.14.13.121 -- premnaspirodiene oxygenase ,
1.14.13.122 -- chlorophyllide-a oxygenase ,
1.14.13.123 -- germacrene A hydroxylase ,
1.14.13.124 -- phenylalanine N-monooxygenase ,
1.14.13.125 -- tryptophan N-monooxygenase ,
1.14.13.126 -- vitamin D3 24-hydroxylase ,
1.14.13.127 -- 3-(3-hydroxyphenyl)propanoate hydroxylase ,
1.14.13.128 -- 7-methylxanthine demethylase ,
1.14.13.129 -- β-carotene 3-hydroxylase ,
1.14.13.130 -- pyrrole-2-carboxylate monooxygenase ,
1.14.13.131 -- dimethyl-sulfide monooxygenase ,
1.14.13.132 -- squalene monooxygenase ,
1.14.13.133 -- pentalenene oxygenase ,
1.14.13.134 -- β-amyrin 11-oxidase ,
1.14.13.135 -- 1-hydroxy-2-naphthoate hydroxylase ,
1.14.13.136 -- 2-hydroxyisoflavanone synthase ,
1.14.13.137 -- indole-2-monooxygenase ,
1.14.13.138 -- indolin-2-one monooxygenase ,
1.14.13.139 -- 3-hydroxyindolin-2-one monooxygenase ,
1.14.13.140 -- 2-hydroxy-1,4-benzoxazin-3-one monooxygenase ,
1.14.13.141 -- cholest-4-en-3-one 26-monooxygenase ,
1.14.13.142 -- 3-ketosteroid 9α-monooxygenase ,
1.14.13.143 -- ent-isokaurene C2-hydroxylase ,
1.14.13.144 -- 9β-pimara-7,15-diene oxidase ,
1.14.13.145 -- ent-cassa-12,15-diene 11-hydroxylase ,
1.14.13.146 -- taxoid 14β-hydroxylase ,
1.14.13.147 -- taxoid 7β-hydroxylase ,
1.14.13.148 -- trimethylamine monooxygenase ,
1.14.13.149 -- phenylacetyl-CoA 1,2-epoxidase ,
1.14.13.150 -- α-humulene 10-hydroxylase ,
1.14.13.151 -- linalool 8-monooxygenase ,
1.14.13.152 -- geraniol 8-hydroxylase ,
1.14.13.153 -- (+)-sabinene 3-hydroxylase ,
1.14.13.154 -- erythromycin 12-hydroxylase ,
1.14.13.155 -- α-pinene monooxygenase ,
1.14.13.156 -- 1,8-cineole 2-endo-monooxygenase ,
1.14.13.157 -- 1,8-cineole 2-exo-monooxygenase ,
1.14.13.158 -- amorpha-4,11-diene 12-monooxygenase ,
1.14.13.159 -- vitamin D 25-hydroxylase ,
1.14.13.160 -- (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase ,
1.14.13.161 -- (+)-camphor 6-exo-hydroxylase ,
1.14.13.162 -- 2,5-diketocamphane 1,2-monooxygenase ,
1.14.13.163 -- 6-hydroxy-3-succinoylpyridine 3-monooxygenase ,
1.14.13.165 -- nitric-oxide synthase [NAD(P)H-dependent] ,
1.14.13.166 -- 4-nitrocatechol 4-monooxygenase ,
1.14.13.167 -- 4-nitrophenol 4-monooxygenase ,
1.14.13.168 -- indole-3-pyruvate monooxygenase ,
1.14.13.169 -- sphinganine C4-monooxygenase ,
1.14.13.170 -- pentalenolactone D synthase ,
1.14.13.171 -- neopentalenolactone D synthase ,
1.14.13.172 -- salicylate 5-hydroxylase ,
1.14.13.173 -- 11-oxo-β-amyrin 30-oxidase ,
1.14.13.174 -- averantin hydroxylase ,
1.14.13.175 -- aflatoxin B synthase ,
1.14.13.176 -- tryprostatin B 6-hydroxylase ,
1.14.13.177 -- fumitremorgin C monooxygenase ,
1.14.13.178 -- methylxanthine N1-demethylase ,
1.14.13.179 -- methylxanthine N3-demethylase ,
1.14.13.180 -- aklavinone 12-hydroxylase ,
1.14.13.181 -- 13-deoxydaunorubicin hydroxylase ,
1.14.13.182 -- 2-heptyl-3-hydroxy-4(1H)-quinolone synthase ,
1.14.13.183 -- dammarenediol 12-hydroxylase ,
1.14.13.184 -- protopanaxadiol 6-hydroxylase ,
1.14.13.185 -- pikromycin synthase ,
1.14.13.186 -- 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase ,
1.14.13.187 -- L-evernosamine nitrososynthase ,
1.14.13.188 -- 6-deoxyerythronolide B hydroxylase ,
1.14.13.189 -- 5-methyl-1-naphthoate 3-hydroxylase ,
1.14.13.190 -- ferruginol synthase ,
1.14.13.191 -- ent-sandaracopimaradiene 3-hydroxylase ,
1.14.13.192 -- oryzalexin E synthase ,
1.14.13.193 -- oryzalexin D synthase ,
1.14.13.194 -- phylloquinone ω-hydroxylase ,
1.14.13.cn -- β-amyrin 28-monooxygenase

Unofficial Reactions:
2-methoxy-6-(all-trans-octaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
2-octaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-octaprenyl)benzene-1,2-diol + NADP+ + H2O ,
3-methylphenol + NADH + oxygen + H+ → 3-hydroxybenzyl alcohol + NAD+ + H2O ,
linalool + NADH + H+ + oxygen → (6E)-8-hydroxylinalool + NAD+ + H2O ,
4-methylphenol + NADH + H+ + oxygen → 4-methylcatechol + NAD+ + H2O ,
2-methylphenol + NADH + H+ + oxygen → 3-methylcatechol + NAD+ + H2O ,
resorcinol + NADH + H+ + oxygen → 1,2,4-benzenetriol + NAD+ + H2O ,
4-nitrotoluene + NADH + H+ + oxygen → 4-nitrobenzyl alcohol + NAD+ + H2O ,
5-hydroxyadamantan-2-one + NADH + oxygen + H+ → 1-hydroxy-4-oxahomoadamantan-5-one + NAD+ + H2O ,
adamantanone + NADH + H+ + oxygen → 4-oxahomoadamantan-5-one + NAD+ + H2O ,
4-chlorophenol + NADPH + oxygen + H+ → 4-chlorocatechol + NADP+ + H2O ,
2-chlorophenol + NADPH + oxygen + H+ → 3-chlorocatechol + NADP+ + H2O ,
3-chlorophenol + NADPH + oxygen + H+ → 3-chlorocatechol + NADP+ + H2O ,
3-chlorophenol + NADPH + oxygen + H+ → 4-chlorocatechol + NADP+ + H2O ,
a jasmonic acid + NADPH + oxygen + H+ → a 12-hydroxyjasmonate + NADP+ + H2O ,
(-)-jasmonate + NADPH + oxygen + H+ → an 11-hydroxyjasmonate + NADP+ + H2O ,
palmitate + NADPH + H+ + oxygen → 16-hydroxypalmitate + NADP+ + H2O ,
16-hydroxypalmitate + NADPH + H+ + oxygen → 10,16-dihydroxypalmitate + NADP+ + H2O ,
oleate + NADPH + oxygen + H+ → 18-hydroxyoleate + NADP+ + H2O ,
laurate + NADPH + oxygen + H+ → ω-hydroxylaurate + NADP+ + H2O ,
decanoate + NADPH + oxygen + H+ → ω-hydroxycaprate + NADP+ + H2O ,
laurate + NADH + oxygen + H+ → ω-hydroxylaurate + NAD+ + H2O ,
laurate + NADPH + oxygen + H+ → ω-1 laurate + NADP+ + H2O ,
elymoclavine aldehyde + NADPH + oxygen → paspalate + NADP+ + H2O ,
agroclavine + NADPH + oxygen + H+ → elymoclavine + NADP+ + H2O ,
coniferaldehyde + NADPH + H+ + oxygen → 5-hydroxy-coniferaldehyde + NADP+ + H2O ,
(4R)-perillyl aldehyde + NADH + oxygen → (4R)-perillate + NAD+ + H2O ,
(4R)-limonene + NADH + oxygen + H+ → (4R)-perillyl alcohol + NAD+ + H2O ,
(22α)-hydroxy-campesterol + NADPH + H+ + oxygen → (22R,23R)-22,23-dihydroxycampesterol + NADP+ + H2O ,
(22α)-hydroxy-campest-4-en-3-one + NADPH + H+ + oxygen → (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP+ + H2O ,
3-epi-6-deoxocathasterone + NADPH + H+ + oxygen → 6-deoxotyphasterol + NADP+ + H2O ,
3-dehydro-6-deoxoteasterone + NADPH + oxygen → 3-dehydroteasterone + NADP+ + H+ + H2O ,
teasterone + NADPH + H+ + oxygen → 7-oxateasterone + NADP+ + H2O ,
typhasterol + NADPH + H+ + oxygen → 7-oxatyphasterol + NADP+ + H2O ,
(2E,6E)-farnesyl methyl ester + NADPH + oxygen + H+ → juvenile hormone III + NADP+ + H2O ,
1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + H+ + oxygen → 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP+ + H2O ,
(2-trans-6-trans)-farnesoate + NADPH + oxygen + H+ → juvenile hormone III acid + NADP+ + H2O ,
aminopyrrolnitrin + NAD(P)H + 2 oxygen + H+ → pyrrolnitrin + NAD(P)+ + 2 H2O ,
N-debenzoyl-(3'-RS)-2'-deoxytaxol + NADPH + oxygen + H+N-debenzoyl-(3'-RS)-taxol + NADP+ + H2O ,
5-methyl-phenazine-1-carboxylate + NADH + oxygen + 2 H+ → pyocyanin + CO2 + NAD+ + H2O ,
(3S,6E)-nerolidol + NADPH + H+ + oxygen → (3E)-4,8-dimethylnona-1,3,7-triene + but-1-en-3-one + NADP+ + 2 H2O ,
4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NADH + oxygen + H+ → 4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+ + 2 H2O ,
24-methylenecycloartanol + NADH + oxygen + H+ → 4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+ + H2O ,
4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NADH + oxygen → 4α-carboxy-4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+ + H2O ,
24-methylenelophenol + NADH + oxygen + H+ → 4α-hydroxymethyl-ergosta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl-ergosta-7,24(241)-dien-3β-ol + NADH + oxygen + H+ → 4α-formyl-ergosta-7,24(241)-dien-3β-ol + NAD+ + 2 H2O ,
4α-formyl-ergosta-7,24(241)-dien-3β-ol + NADH + oxygen → 4α-carboxy-ergosta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
24-ethylidenelophenol + NADH + oxygen + H+ → 4α-hydroxymethyl-stigmasta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl-stigmasta-7,24(241)-dien-3β-ol + NADH + oxygen + H+ → 4α-formyl-stigmasta-7,24(241)-dien-3β-ol + NAD+ + 2 H2O ,
4α-formyl-stigmasta-7,24(241)-dien-3β-ol + NADH + oxygen → 4α-carboxy-stigmasta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
cycloartenol + NADH + oxygen + H+ → 4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NADH + oxygen + H+ → 4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD+ + 2 H2O ,
4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NADH + oxygen → 4α-carboxy,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD+ + H2O ,
4α-methyl-5α-cholesta-7,24-dien-3β-ol + NADH + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-7,24-dien-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl-5α-cholesta-7,24-dien-3β-ol + NADH + oxygen + H+ → 4α-formyl-5α-cholesta-7,24-dien-3β-ol + NAD+ + 2 H2O ,
4α-formyl-5α-cholesta-7,24-dien-3β-ol + NADH + oxygen → 4α-carboxy-5α-cholesta-7,24-dien-3β-ol + NAD+ + H2O ,
behenate + NADPH + oxygen + H+ → 22-hydroxydocosanoate + NADP+ + H2O ,
a fatty acid + NADPH + oxygen + H+ → an in-chain hydroxy fatty acid + NADP+ + H2O ,
benzoate + NADPH + oxygen + H+ → 6-hydroxy-2-cyclohexen-one-carboxylate + NADP+ ,
(+)-7-iso-jasmonoyl-L-isoleucine + NADPH + oxygen + H+ → (3R, 7S)-12-hydroxy-jasmonoyl-L-isoleucine + NADP+ + H2O ,
justicidin B + NADPH + oxygen + H+ → diphyllin + NADP+ + H2O ,
(+)-α-santalene + NADPH + oxygen + H+ → (+)-α-santalol + NADP+ + H2O ,
kauralexin A1 + NADPH + oxygen → kauralexin A3 + NADP+ + H2O + H+ ,
kauralexin A3 + NADPH + oxygen → kauralexin A2 + NADP+ + H2O ,
ent-kaurene + NADPH + H+ + oxygen → kauralexin A1 + NADP+ + H2O ,
kauralexin B1 + NADPH + oxygen → kauralexin B3 + NADP+ + H2O + H+ ,
kauralexin B3 + NADPH + oxygen → kauralexin B2 + NADP+ + H2O ,
ent-isokaurene + NADPH + H+ + oxygen → kauralexin B1 + NADP+ + H2O ,
4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + NADPH + oxygen → zealexin A1 + NADP+ + H2O ,
pentalen-13-al + NADPH + oxygen → 1-deoxypentalenate + NADP+ + H2O ,
(S)-β-macrocarpene + NADPH + H+ + oxygen → [4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl] methanol + NADP+ + H2O ,
[4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl] methanol + NADPH + oxygen + H+ → 4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + NADP+ + 2 H2O ,
30-hydroxy-β-amyrin + NADPH + oxygen + H+ → 11α,30-dihydroxy-β-amyrin + NADP+ + H2O ,
cholesterol + NADH + oxygen + H+ → (25R)-cholest-5-ene-3β,26-diol + NAD+ + H2O ,
androst-4-ene-3,17-dione + NADH + oxygen + H+ → 9α-hydroxy-androst-4-en-3,17-dione + NAD+ + H2O ,
3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + NADH + oxygen + H+ → 9α-hydroxy-androst-4-en-3-one-17-propanoyl-CoA + NAD+ + H2O ,
3-one-23,24-bisnorchol-1,4-dien-22-yl-CoA + NADH + oxygen + H+ → 9α-hydroxy-3-oxo-23,24-bisnorchol-1,4-dien-22-yl-CoA + NAD+ + H2O ,
3-one-23,24-bisnorchol-4-en-22-oate + NADH + oxygen + H+ → 3-one-9-hydroxy-23,24-bisnorchol-4-en-22-oate + NAD+ + H2O ,
3-oxo-24-ethyl-cholest-4-ene + NADH + oxygen + H+ → 3-oxo-24-ethyl-26-hydroxy-cholest-4-ene + NAD+ + H2O ,
dimethylamine + NADPH + oxygen + H+ → methylamine + formaldehyde + NADP+ + H2O ,
8,8a-deoxyoleandolide + NADPH + oxygen → oleandolide + NADP+ + H2O + H+ ,
(6E)-8-hydroxylinalool + NADH + oxygen + H+ → (6E)-8-oxolinalool + NAD+ + 2 H2O ,
tetrahomomethionine + NADPH + oxygen → N-hydroxy-tetrahomomethionine + NADP+ + H2O ,
N-hydroxyhexahomomethioniate + NADPH + oxygen + H+N,N-dihydroxyhexahomomethioniate + NADP+ + H2O ,
pentahomomethionine + NADPH + oxygen → N-hydroxypentahomomethionine + NADP+ + H2O ,
N-hydroxypentahomomethionine + NADPH + oxygen + H+N,N-dihydroxypentahomomethionine + NADP+ + H2O ,
L-homomethionine + NADPH + oxygen → N-hydroxyhomomethionine + NADP+ + H2O ,
N-hydroxyhomomethionine + NADPH + oxygen + H+N,N-dihydroxyhomomethionine + NADP+ + H2O ,
L-dihomomethionine + NADPH + oxygen → N-hydroxy-L-dihomomethionine + NADP+ + H2O ,
N-hydroxy-L-dihomomethionine + NADPH + oxygen + H+N,N-dihydroxy-L-dihomomethionine + NADP+ + H2O ,
trihomomethionine + NADPH + oxygen → N-hydroxytrihomomethionine + NADP+ + H2O ,
N-hydroxytrihomomethionine + NADPH + oxygen + H+N, N-dihydroxytrihomomethionine + NADP+ + H2O ,
N, N-dihydroxytrihomomethionine + H+ = 6-methylthiohexanaldoxime + CO2 + H2O ,
N-hydroxy-tetrahomomethionine + NADPH + oxygen + H+N, N-dihydroxy-tetrahomomethionine + NADP+ + H2O ,
hexahomomethionine + NADPH + oxygen → N-hydroxyhexahomomethioniate + NADP+ + H2O ,
3,6-diketocamphane + NADH + H+ + oxygen → (-)-5-oxo-1,2-campholide + NAD+ + H2O ,
2-propylphenol + NADH + oxygen + H+ → 3-propylcatechol + NAD+ + H2O ,
2-isopropylphenol + NADH + oxygen + H+ → 3-isopropylcatechol + NAD+ + H2O ,
2,2',3-trihydroxybiphenyl + NADH + oxygen + H+ → 2,2',3,3'-tetrahydroxybiphenyl + NAD+ + H2O ,
2,3-dihydroxybenzoate + NADH + oxygen + 2 H+ → pyrogallol + CO2 + NAD+ + H2O ,
7-dehydrocholesterol + NADPH + H+ + oxygen → 7-ketocholesterol + NADP+ + H2O ,
protodeoxyviolaceinate + NADPH + oxygen + H+ → protoviolaceinate + NADP+ + H2O ,
protoviolaceinate + NADPH + oxygen + H+ → violaceinate + NADP+ + H2O ,
protodeoxyviolaceinate + NADPH + oxygen + H+ → deoxyviolaceinate + NADP+ + H2O ,
premithramycin B + NADPH + oxygen + H+ → premithramycin B lactone + NADP+ + H2O ,
elymoclavine + NADPH + oxygen + H+ → elymoclavine aldehyde + NADP+ + 2 H2O ,
taxusin + NADPH + oxygen + H+ → 2α-hydroxytaxusin + NADP+ + H2O ,
7β-hydroxytaxusin + NADPH + oxygen + H+ → 2α, 7β-dihydroxytaxusin + NADP+ + H2O ,
2α-hydroxytaxusin + NADPH + oxygen + H+ → 2α, 7β-dihydroxytaxusin + NADP+ + H2O ,
β-amyrin + NADPH + H+ + oxygen → 30-hydroxy-β-amyrin + NADP+ + H2O ,
lupeol + NADPH + oxygen + H+ → betulin + NADP+ + H2O ,
betulinic aldehyde + NADPH + oxygen + H+ → betulinate + NADP+ + H2O ,
α-amyrin + NADPH + oxygen + H+ → uvaol + NADP+ + H2O ,
ursolic aldehyde + NADPH + oxygen + H+ → ursolate + NADP+ + H2O ,
lupeol + 3 NADPH + 3 oxygen + 3 H+ → betulinate + 3 NADP+ + 4 H2O ,
α-amyrin + 3 NADPH + 3 oxygen + 3 H+ → ursolate + 3 NADP+ + 4 H2O ,
ent-kaur-16-en-19-oate + NADPH + oxygen + 2 H+ → steviol + NADP+ + H2O ,
O-methylandrocymbine + NADPH + oxygen → N-formyldemecolcine + NADP+ + H2O + 2 H+ ,
triethylamine + NADPH + oxygen → triethylamine N-oxide + NADP+ + H2O ,
diethylamine + NADPH + oxygen → diethylamine N-oxide + NADP+ + H2O ,
ethylamine + NADPH + H+ + oxygen → acetaldehyde + ammonium + NADP+ + H2O ,
4-hydroxyphenylacetonitrile + NADPH + oxygen + H+ → (R)-4-hydroxymandelonitrile + NADP+ + H2O ,
(+)-taxifolin + NADPH + oxygen + H+ → dihydromyricetin + NADP+ + H2O ,
allocryptopine + NADPH + oxygen + H+ → 6-hydroxy-allocryptopine + NADP+ + H2O ,
3,7,4'-trimethylquercetin + NADPH + oxygen + H+ → 2'-hydroxy 3,7,4'-trimethylquercetin + NADP+ + H2O ,
3,6,7,4'-tetramethylquercetagetin + NADPH + oxygen + H+ → 2'-hydroxy 3,6,7,4'-tetramethylquercetagetin + NADP+ + H2O ,
quercetin + NADPH + oxygen + H+ → quercetagetin + NADP+ + H2O ,
zeaxanthin + NADH + oxygen + H+ → caloxanthin + NAD+ + H2O ,
all-trans-β-carotene + 2 NADH + 2 H+ + 2 oxygen → (2R,2'R)-dihydroxy-all-trans-β-carotene + 2 NAD+ + 2 H2O ,
(2S)-naringenin + NADPH + oxygen → 2-hydroxynaringenin + NADP+ + H2O ,
eriodictyol + NADPH + oxygen + 2 H+ → 2-hydroxyeriodictyol + NADP+ + H2O ,
(2S)-pinocembrin + NADPH + oxygen + H+ → 2,5,7-trihydroxyflavanone + NADP+ + H2O ,
(Z)-2-methylbutanal oxime + NADPH + oxygen + H+ → 2-hydroxy-2-methylbutyronitrile + NADP+ + 2 H2O ,
chrysin + NADPH + oxygen + 2 H+ → baicalein + NADP+ + H2O ,
3-hexaprenyl-4-aminobenzoate + NADPH + oxygen + H+ → 3-hexaprenyl-4-amino-5-hydroxybenzoate + NADP+ + H2O ,
2-hexaprenyl-6-methoxyaminobenzene + NADPH + oxygen + H+ → 2-hexaprenyl-6-methoxyaminophenol + NADP+ + H2O ,
oleoyl-CoA + NADH + oxygen + H+ → ricinoleyl-CoA + NAD+ + H2O ,
(11Z)-eicos-11-enoyl-CoA + NADH + oxygen + H+ → lesqueroloyl-CoA + NAD+ + H2O ,
L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → (R)-β-hydroxy-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
β-oxo-L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → 2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
indole-3-acetate + NADH + oxygen + H+ → 2-hydroxy-indole-3-acetate + NAD+ + H2O ,
indole + NADH + oxygen + H+ → indoxyl + NAD+ + H2O ,
genkwanin + NADPH + oxygen + H+ → scutellarein 7-methyl ether + NADP+ + H2O ,
apigenin-7,4'-dimethyl ether + NADPH + oxygen + H+ → ladanein + NADP+ + H2O ,
(S)-sakuranetin + NADPH + oxygen + H+ → carthamidin-7-methyl ether + NADP+ + H2O ,
aurachin D + NADPH + oxygen + H+ → 9'-hydroxy-aurachin D + NADP+ + H2O ,
9'-hydroxy-aurachin D + NADPH + oxygen + H+ → aurachin RE + NADP+ + H2O ,
aurachin D + NADPH + oxygen + H+ → aurachin C + NADP+ + H2O ,
aurachin B + NAD(P)H + oxygen + H+ → aurachin B epoxide + NAD(P)+ + H2O ,
aurachin C + NAD(P)H + oxygen + H+ → aurachin C epoxide + NAD(P)+ + H2O ,
β-myrcene + NADPH + H+ + oxygen → (4S)-(+)-ipsdienol + NADP+ + H2O ,
β-myrcene + NADPH + H+ + oxygen → (4R)-(-)-ipsdienol + NADP+ + H2O ,
mycinamicin IV + NADPH + oxygen + H+ → mycinamicin V + NADP+ + H2O ,
mycinamicin V + NADPH + oxygen + H+ → mycinamicin II + NADP+ + H2O ,
mycinamicin IV + NADPH + oxygen + H+ → mycinamicin I + NADP+ + H2O ,
geraniol + NADPH + oxygen + H+ → 9-hydroxygeraniol + NADP+ + H2O ,
CMP-5'-3-aminopropylphosphonate + NADPH + oxygen → CMP-5'-N-hydroxy-3-aminopropylphosphonate + NADP+ + H2O ,
O-aminobenzaldehyde + NADH + oxygen → anthranilate + NAD+ + H2O ,
O-aminobenzaldehyde + NADPH + oxygen + H+ → anthranil + NADP+ + 2 H2O ,
O-aminobenzaldehyde + NADPH + oxygen → anthranilate + NADP+ + H2O ,
iridotrial + NADPH + oxygen → 7-deoxyloganetate + NADP+ + H2O ,
7-deoxyloganetin + NADPH + oxygen + H+ → loganetin + NADP+ + H2O ,
2-nonaprenylphenol + NADPH + oxygen + H+ → 2-(all-trans-nonaprenyl)benzene-1,4-diol + NADP+ + H2O ,
β-amyrin + NAD(P)H + oxygen + H+ → 12,13β-epoxy-β-amyrin + NAD(P)+ + H2O ,
12,13β-epoxy-β-amyrin + NAD(P)H + oxygen + H+ → 12,13β-epoxy-16β-hydroxy-β-amyrin + NAD(P)+ + H2O ,
β-amyrin + NAD(P)H + oxygen + H+ → 16β-hydroxy-β-amyrin + NAD(P)+ + H2O ,
16β-hydroxy-β-amyrin + NAD(P)H + oxygen + H+ → 12,13β-epoxy-16β-hydroxy-β-amyrin + NAD(P)+ + H2O ,
ent-sandaracopimaradiene + NADPH + H+ + oxygen → 7β-hydroxy-ent-sandaracopimaradiene + NADP+ + H2O ,
cyclooctat-9-en-5,7-diol + NADPH + oxygen + H+ → cyclooctatin + NADP+ + H2O ,
cyclooctat-9-en-7-ol + NADPH + oxygen + H+ → cyclooctat-9-en-5,7-diol + NADP+ + H2O ,
3β-hydroxy-12,15-cassadiene-11-one + NADPH + oxygen + H+ → 2β,3β-dihydroxy-12,15-cassadiene-11-one + NADP+ + H2O ,
7β-hydroxy-ent-sandaracopimaradiene + NADPH + oxygen + H+ → oryzalexin D + NADP+ + H2O ,
ent-cassa-12,15-diene + NADPH + oxygen + H+ → 3α-hydroxy-ent-cassadiene + NADP+ + H2O ,
(-)-9β-pimara-7,15-diene + NADPH + oxygen + H+ → 6β-hydroxy-syn-pimaradiene + NADP+ + H2O ,
1,3,7-trimethylurate + NADH + oxygen + 3 H+ → 1,3,7-trimethyl-5-hydroxyisourate + NAD+ + H2O ,
germacra-1(10),4,11(13)-trien-12-oate + NADPH + oxygen + H+ → 8β-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP+ + H2O ,
ent-cassa-12,15-diene + NADPH + oxygen + H+ → 2α-hydroxy-ent-cassadiene + NADP+ + H2O ,
3-methylphenol + NADPH + oxygen + H+ → 3-hydroxybenzyl alcohol + NADP+ + H2O ,
3-methylphenol + NADPH + oxygen + H+ → toluquinol + NADP+ + H2O ,
3-hydroxybenzyl alcohol + NADPH + H+ + oxygen → gentisyl alcohol + NADP+ + H2O ,
3-geranylgeranylindole + NADPH + oxygen + H+ → 10,11-epoxy-3-geranylgeranylindole + NADP+ + H2O ,
emindole-SB + NADPH + oxygen + H+ → 14,15-epoxyemindole-SB + NADP+ + H2O ,
paspaline + 4 NADPH + 4 oxygen + 4 H+ → β-10-hydroxy-12-demethyl-11,12-dehydropaspaline + formate + 4 NADP+ + 5 H2O + H+ ,
β-10-hydroxy-12-demethyl-11,12-dehydropaspaline + NADPH + oxygen + H+ → 13-desoxypaxilline + NADP+ + 2 H2O ,
13-desoxypaxilline + NADPH + oxygen + H+ → paxilline + NADP+ + H2O ,
(+)-costunolide + NADPH + oxygen + H+ → parthenolide + NADP+ + H2O ,
parthenolide + NADPH + oxygen + H+ → 3β-hydroxyparthenolide + NADP+ + H2O ,
(+)-costunolide + NADPH + oxygen + H+ → 3β-hydroxycostunolide + NADP+ + H2O ,
flaviolin + NADH + H+ + oxygen → mompain + NAD+ + H2O ,
fusicocca-2,10(14)-diene + NADPH + oxygen + H+ → fusicocca-2,10(14)-diene-8β-ol + NADP+ + H2O ,
fusicocca-2,10(14)-diene-8β-ol + NADPH + H+ + oxygen → fusicocca-2,10(14)-diene-8β,16-diol + NADP+ + H2O ,
4-sulfoacetophenone + NADPH + H+ + oxygen → 4-sulfophenyl acetate + NADP+ + H2O ,
a fatty acid + NADPH + oxygen + H+ → an (ω-1)-hydroxy fatty acid + NADP+ + H2O ,
paspaline + NADPH + oxygen + H+ = terpendole E + NADP+ + H2O ,
13-desoxypaxilline + NADPH + oxygen + H+ → paspalicine + NADP+ + 2 H2O ,
paspalicine + NADPH + oxygen + H+ → paspalinine + NADP+ + H2O ,
fumiquinazoline F + 2 NAD(P)H + 4 H+ + 2 oxygen → fumiquinazoline F-indoline-2,3-diol + 2 NAD(P)+ + 2 H2O ,
asperlicin C + NADH + H+ + oxygen → asperlicin E + NAD+ + H2O ,
α-cyclopiazonate + NAD(P)H + H+ + oxygen → 2-oxocyclopiazonate + NAD(P)+ + H2O ,
L-homomethionine + 2 NADPH + 2 oxygen + 2 H+ → 4-methylthiobutanaldoxime + CO2 + 2 NADP+ + 3 H2O ,
2-hydroxy-indole-3-acetate + NADH + oxygen + H+ → 3-hydroxy-2-oxo-indole-3-acetate + NAD+ + H2O ,
campesterol + NADPH + H+ + oxygen → (22α)-hydroxy-campesterol + NADP+ + H2O ,
(5α)-campestan-3-one + NADPH + H+ + oxygen → (22S,24R)-22-hydroxy-5α-ergostan-3-one + NADP+ + H2O ,
campest-4-en-3-one + NADPH + H+ + oxygen → (22α)-hydroxy-campest-4-en-3-one + NADP+ + H2O ,
an alkane + NADPH + oxygen + H+ → a long-chain alcohol + NADP+ + H2O ,
a fatty acid + NADPH + oxygen + H+ → an ω-hydroxy fatty acid + NADP+ + H2O ,
7-deoxyloganate + NADPH + H+ + oxygen → loganate + NADP+ + H2O ,
2-methylpropionitrile + NADPH + H+ + oxygen → acetone cyanohydrin + NADP+ + H2O ,
L-carnitine + NAD(P)H + oxygen + H+ → L-malic semialdehyde + trimethylamine + NAD(P)+ + H2O ,
dibenzothiophene + NADH + H+ + oxygen → dibenzothiophene-5-oxide + NAD+ + H2O ,
dibenzothiophene-5-oxide + NADH + H+ + oxygen → dibenzothiophene-5,5-dioxide + NAD+ + H2O ,
p-cymene + NADH + H+ + oxygen → p-cumic alcohol + NAD+ + H2O ,
6-oxocampestanol + NADPH + H+ + oxygen → cathasterone + NADP+ + H2O ,
castasterone + NADPH + H+ + oxygen → brassinolide + NADP+ + H2O ,
(2S)-naringenin + NADPH + oxygen → apigenin + NADP+ + 2 H2O ,
eriodictyol + NADPH + H+ + oxygen → luteolin + NADP+ + 2 H2O ,
6,7,4'-trihydroxyflavanone + NADPH + H+ + oxygen → 2,6,7,4'-tetrahydroxyisoflavanone + NADP+ + H2O ,
campestanol + NADPH + H+ + oxygen → 6-deoxocathasterone + NADP+ + H2O ,
a dihydroceramide + NADPH + oxygen + H+ → an α hydroxydihydroceramide + NADP+ + H2O ,
a dihydroceramide + NAD(P)H + oxygen + H+ → a phytoceramide + NAD(P)+ + H2O ,
sitosterol + NADPH + H+ + oxygen → (22α)-hydroxy-sitosterol + NADP+ + H2O ,
isofucosterol + NADPH + H+ + oxygen → (22α)-hydroxy-isofucosterol + NADP+ + H2O ,
cholestanol + NADPH + H+ + oxygen → (22α)-hydroxy-cholestanol + NADP+ + H2O ,
isoliquiritigenin + NADPH + H+ + oxygen → butein + NADP+ + H2O ,
β-amyrin + NADPH + H+ + oxygen → sophoradiol + NADP+ + H2O ,
24-hydroxy-β-amyrin + NADPH + H+ + oxygen → soyasapogenol B + NADP+ + H2O ,
(S)-cis-N-methylstylopine + NADPH + oxygen → protopine + NADP+ + H2O ,
abieta-7,13-diene-18-al + NADPH + oxygen → abieta-7,13-diene-18-oate + NADP+ + H2O ,
levopimaradiene + NADPH + H+ + oxygen → levopimaradienol + NADP+ + H2O ,
levopimaradienol + NADPH + H+ + oxygen → levopiramadiene-diol + NADP+ + H2O ,
levopimaradienal + NADPH + oxygen → levopimaric acid + NADP+ + H2O ,
neoabietadiene + NADPH + H+ + oxygen → neoabietadienol + NADP+ + H2O ,
neoabietadienol + NADPH + H+ + oxygen → neoabietadiene-diol + NADP+ + H2O ,
neoabietadienal + NADPH + oxygen → neoabietic acid + NADP+ + H2O ,
palustradiene + NADPH + H+ + oxygen → palustradienol + NADP+ + H2O ,
palustradienol + NADPH + H+ + oxygen → palustradiene-diol + NADP+ + H2O ,
palustradienal + NADPH + oxygen → palustric acid + NADP+ + H2O ,
dehydroabietadiene + NADPH + H+ + oxygen → dehydroabietadienol + NADP+ + H2O ,
dehydroabietadienol + NADPH + H+ + oxygen → dehydroabietadiene-diol + NADP+ + H2O ,
dehydroabietadienal + NADPH + oxygen → dehydroabietate + NADP+ + H2O ,
(+)-isopimara-7,15-diene + NADPH + H+ + oxygen → isopimaradienol + NADP+ + H2O ,
isopimaradienol + NADPH + H+ + oxygen → isopimaradiene-diol + NADP+ + H2O ,
isopimaradienal + NADPH + oxygen → isopimaric acid + NADP+ + H2O ,
(3R,6E)-nerolidol + NADPH + H+ + oxygen → (3E)-4,8-dimethylnona-1,3,7-triene + but-1-en-3-one + NADP+ + 2 H2O ,
(+)-pinoresinol + NADPH + H+ + oxygen → (+)-piperitol + NADP+ + 2 H2O ,
(+)-piperitol + NADPH + H+ + oxygen → (+)-sesamin + NADP+ + 2 H2O ,
tryptamine + NAD(P)H + H+ + oxygen → serotonin + NAD(P)+ + H2O ,
deoxypodophyllotoxin + NADPH + H+ + oxygen → β-peltatin + NADP+ + H2O ,
(+)-δ-cadinene + NADPH + H+ + oxygen → 8-hydroxy-(+)-δ-cadinene + NADP+ + H2O ,
2-heptaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-heptaprenyl)benzene-1,2-diol + NADP+ + H2O ,
2-methoxy-6-(all-trans-heptaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-heptaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol + NADPH + oxygen + H+ → 3-demethylubiquinol-7 + NADP+ + H2O ,
2-decaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-decaprenyl)benzene-1,2-diol + NADP+ + H2O ,
2-methoxy-6-(all-trans-decaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
2-nonaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-nonaprenyl)benzene-1,2-diol + NADP+ + H2O ,
3-octaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + NADP+ + H2O ,
3-nonaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-nonaprenylbenzoate + NADP+ + H2O ,
3-decaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + NADP+ + H2O ,
3-heptaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + NADP+ + H2O ,
(6E)-8-oxogeranial + NADPH + oxygen + H+ → iridotrial + NADP+ + H2O ,
a limonene + NADPH + H+ + oxygen → a limonene-1,2-epoxide + NADP+ + H2O ,
(4S)-limonene + NADPH + oxygen + H+ → (-)-cis-carveol + NADP+ + H2O ,
thalianol + NAD(P)H + oxygen → a thalian-diol + NAD(P)+ + H2O ,
2-methylbutyronitrile + NADPH + H+ + oxygen → 2-hydroxy-2-methylbutyronitrile + NADP+ + H2O ,
linoleate + NAD(P)H + oxygen + H+ → (+)-vernolate + NAD(P)+ + H2O ,
dimethyl sulfide + NADPH + oxygen + H+ → dimethyl sulfoxide + NADP+ + H2O ,
dimethyl sulfoxide + NADPH + oxygen + H+ → dimethyl sulfone + NADP+ + H2O ,
9,10-epoxystearate + NADPH + H+ + oxygen → 9,10-epoxy-18-hydroxystearate + NADP+ + H2O ,
(9R,10S)-dihydroxystearate + NADPH + H+ + oxygen → 9,10,18-trihydroxystearate + NADP+ + H2O ,
2-chloro-4-methylphenol + NADPH + oxygen + H+ → 3-chloro-5-methylcatechol + NADP+ + H2O ,
3-chlorotoluene + NADH + H+ + oxygen → 3-chlorobenzyl alcohol + NAD+ + H2O ,
a [protein chain elongation factor EF-P]-L-lysine34 + NADPH + oxygen + H+ → a [protein chain elongation factor EF-P]-5-hydroxy-L-lysine34 + NADP+ + H2O ,
2-hexaprenyl-6-methoxyphenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-hexaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
3-hexaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + NADP+ + H2O ,
cis-abscisic alcohol + NAD(P)+ + oxygen → 2-cis-abscisate + NAD(P)H + H2O ,
trans-abscisic alcohol + NAD(P)+ + oxygen → 2-trans-abscisate + NAD(P)H + H2O ,
17-α-hydroxyprogesterone + NADPH + H+ + oxygen → 11-desoxycortisol + NADP+ + H2O ,
progesterone + NADPH + H+ + oxygen → 11-deoxycorticosterone + NADP+ + H2O ,
L-dihomomethionine + 2 NADPH + 2 oxygen + 2 H+ → 5-methylthiopentanaldoxime + CO2 + 2 NADP+ + 3 H2O ,
trihomomethionine + 2 NADPH + 2 oxygen + 2 H+ → CO2 + 6-methylthiohexanaldoxime + 2 NADP+ + 3 H2O ,
tetrahomomethionine + 2 NADPH + 2 H+ + 2 oxygen → CO2 + 7-methylthioheptanaldoxime + 2 NADP+ + 3 H2O ,
pentahomomethionine + 2 NADPH + 2 oxygen + 2 H+ → 8-methylthiooctanaldoxime + CO2 + 2 NADP+ + 3 H2O ,
hexahomomethionine + 2 NADPH + 2 oxygen + 2 H+ → CO2 + 9-methylthiononanaldoxime + 2 NADP+ + 3 H2O ,
toluene + NADH + H+ + oxygen → 2-methylphenol + NAD+ + H2O ,
toluene + NADH + H+ + oxygen → 4-methylphenol + NAD+ + H2O ,
toluene + a reduced electron acceptor + oxygen → 4-methylphenol + an oxidized electron acceptor + H2O ,
toluene + NADH + H+ + oxygen → benzyl alcohol + NAD+ + H2O ,
zeaxanthin + 2 NADH + 2 H+ + 2 oxygen → nostoxanthin + 2 NAD+ + 2 H2O ,
mycinamicin VIII + NADPH + oxygen + H+ → mycinamicin VII + NADP+ + H2O ,
5-O-β-mycaminosyltylactone + NADPH + oxygen + H+ → 20-hydroxy-5-O-mycaminosyltylactone + NADP+ + H2O ,
cyclo(L-Phe-L-Ser) + 2 NAD(P)H + 2 H+ + 2 oxygen → 3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine + 2 NAD(P)+ + 2 H2O

Enzymes and Genes:
cyclo(L-Phe-L-Ser) hydroxylase : gliC ( Aspergillus fumigatus )
5-O-mycaminosyltylactone C20-hydroxylase : tylI ( Streptomyces fradiae )
mycinamicin VIII monooxygenase complex : mycCII , mycCI ( Micromonospora griseorubida )
toluene-4-monooxygenase : tmoA , tmoB , tmoE , tmoD , tmoC , tmoF ( Pseudomonas mendocina (pWWO) or (pTOL) )
steroid 21-monooxygenase : CYP21A2 ( Homo sapiens )
EF-P-Lys34 hydroxylase : epmC ( Escherichia coli K-12 substr. MG1655 )
xylene monooxygenase : xylA , xylM ( Pseudomonas putida mt-2 )
trimethylamine monooxygenase : tmm ( Methylocella silvestris )
dimethylsulfoxide oxygenase : dsoA , dsoB , dsoC , dsoD , dsoE , dsoF ( Acinetobacter sp. strain 20B )
CYP77A4 : AT5G04660 ( Arabidopsis thaliana col )
linoleate epoxygenase (cytochrome P450) ( Euphorbia lagascae )
Δ12 linoleate epoxygenase (fatty acid desaturase-like) : Cpal2 ( Crepis palaestina )
thalianol hydroxylase : THAH ( Arabidopsis thaliana col )
ubiquinone biosynthesis monooxygenase COQ6 : COQ6 ( Homo sapiens )
(+)-δ-cadinene-8-hydroxylase : CYP706B1 ( Gossypium arboreum )
deoxypodophyllotoxin 6-hydroxylase ( Linum flavum )
tryptamine 5-hydroxylase ( Juglans regia )
(+)-piperitol/(+)-sesamin synthase : CYP81Q2 ( Sesamum radiatum )
(+)-piperitol/(+)-sesamin synthase : CYP81Q1 ( Sesamum indicum )
abietadienol hydroxylase : CYP720B1 ( Pinus taeda )
(S)-cis-N-methylstylopine 14-hydroxylase/(S)-N-methylcanadine 14-hydroxylase : CYP82N4 ( Papaver somniferum )
(S)-cis-N-methylstylopine 14-hydroxylase/(S)-N-methylcanadine 14-monooxygenase ( Corydalis vaginans )
chalcone 3-hydroxylase ( Dahlia pinnata )
sphingolipid long-chain base 4-hydroxylase ( Zea mays )
sphingolipid very long chain fatty acid α-hydroxylase : AT2G34770 ( Arabidopsis thaliana col )
isoflavone synthase : IFS-Tp ( Trifolium pratense )
isoflavone synthase : IFS1 ( Glycine max )
isoflavone synthase : CYP Ge-8 ( Glycyrrhiza echinata )
apigenin synthase : CYP93B23 ( Ocimum basilicum )
flavone synthase II : CYP93B2 ( Gerbera hybrid cultivar )
brassinolide synthase : CYP85A3 ( Solanum lycopersicum )
p-cymene monooxygenase : cymAa , cymAb ( Pseudomonas putida F1 )
dibenzothiophene monooxygenase : dszC ( Rhodococcus YH3-3 )
carnitine monooxygenase complex : cntB , cntA ( Acinetobacter baumannii ATCC 19606 = CIP 70.34 )
carnitine monooxygenase ( Acinetobacter calcoaceticus )
n-alkane monooxygenase system : NCP1 , CYP52A3-A ( Candida maltosa )
steroid 22α-hydroxylase : CYP90B1 ( Arabidopsis thaliana col )
2-hydroxy-indole-3-acetate monooxygenase : iacE ( Pseudomonas putida 1290 )
α-cyclopiazonate hydroxylase : CpaH ( Aspergillus oryzae )
asperlicin C monooxygenase : AspB ( Aspergillus alliaceus )
fumiquinazoline F monooxygenase : Af12060 ( Aspergillus fumigatus )
cytochrome P450 monooxygenase, AtmQ : atmQ ( Aspergillus flavus )
cytochrome P450 monooxygenase, TerQ : terQ ( Tolypocladium album )
4-sulfoacetophenone monooxygenase : CtesDRAFT_PD5437 ( Comamonas testosteroni KF-1 )
fusicoccadiene 8-ol C-16 hydroxylase : fc8,16h ( Alternaria brassicicola ATCC 96836 )
fusicoccadiene C-8 hydroxylase : fc8h ( Alternaria brassicicola ATCC 96836 )
1,3,6,8-tetrahydroxynaphthalene monooxygenase : MomA ( Streptomyces antibioticus )
sesquiterpenoid 3β-hydroxylase : CYP71CB1 ( Tanacetum parthenium )
parthenolide synthase : CYP71CA1 ( Tanacetum parthenium )
cytochrome P450 monooxygenase, PaxQ : paxQ ( Penicillium paxilli ATCC 26601 )
multifunctional cytochrome P450 monooxygenase, AtmP : atmP ( Aspergillus flavus )
multifunctional cytochrome P450 monooxygenase, PaxP : paxP ( Penicillium paxilli ATCC 26601 )
FAD-dependent monooxygenase, PaxM : paxM ( Penicillium paxilli ATCC 26601 )
cytochrome P450 CYP619C2 : patI ( Aspergillus clavatus NRRL 1980 )
cytochrome P450 CYP619C3 : patH ( Aspergillus clavatus NRRL 1980 )
germacrene A acid 8β-hydroxylase : CYP71BL1 ( Helianthus annuus )
trimethyluric acid monooxygenase : tmuM ( Pseudomonas sp. CBB1 )
cytochrome P450 dependent diterpene olefin hydroxylase : KOL4 ( Oryza sativa )
ent-cassadiene-C2-hydroxylase : CYP71Z7 ( Oryza sativa )
octat-9-en-7-ol 5-monooxygenase : cotB3 ( Streptomyces melanosporofaciens )
cyclooctat-9-en-5,7-diol C18-monooxygenase : cotB4 ( Streptomyces melanosporofaciens )
cytochrome P450 dependent ent-sandaracopimardiene 9β-hydroxylase : CYP76M6 ( Oryza sativa )
cytochrome P450 dependent ent-sandaracopimardiene 7β-hydroxylase : CYP76M8 ( Oryza sativa )
cytochrome P450 dependent β-amyrin monooxygenase : SAD2 ( Avena strigosa )
CMP-5'-3-aminopropylphosphonate hydroxylase : frbG ( Streptomyces rubellomurinus )
mycinamicin IV hydroxylase/epoxidase : mycG ( Micromonospora griseorubida )
myrcene hydroxylase : CYP9T3 ( Ips pini )
myrcene hydroxylase : CYP9T2 ( Ips pini )
aurachin C monooxygenase : auaG ( Stigmatella aurantiaca Sg a15 )
aurachin B monooxygenase : auaJ ( Stigmatella aurantiaca Sg a15 )
aurachin D N-monooxygenase : auaF ( Stigmatella aurantiaca Sg a15 )
9'-hydroxy-aurachin D monooxygenase : rauA ( Rhodococcus erythropolis JCM 6824 )
flavone-6-hydroxylase : CYP82D62 ( Mentha x piperita )
genkwanin 6-hydroxylase : CYP82D33 ( Ocimum basilicum )
cytochrome P450 2E1 : CYP2E1 ( Homo sapiens )
indole monooxygenase : idoA ( Pseudomonas alcaligenes PA-10 )
indole monooxygenase / indole-3-acetate monooxygenase : iacA ( Pseudomonas putida 1290 )
L-tyrosine-[NovH-protein] β-hydroxylase : novI ( Actinoalloteichus cyanogriseus )
oleate 12-hydroxylase : AH12 ( Physaria lindheimeri )
oleate 12-hydroxylase:desaturase : AH12 ( Physaria fendleri )
oleate 12-hydroxylase : FAH12 ( Ricinus communis )
oleate 12-hydroxylase : FAH12 ( Ricinus communis )
3-hexaprenyl-benzoate-5-monoxygenase : COQ6 ( Saccharomyces cerevisiae )
CYP71E7 : CYP71E7 ( Manihot esculenta )
flavanone 2-hydroxylase : CYP93G2 ( Oryza sativa )
zeaxanthin 2,2'-β-hydroxylase : crtG ( Sphingomonas elodea )
flavonol 6-hydroxylase ( Rudbeckia hirta )
flavonol 6-hydroxylase ( Tagetes erecta )
flavonol 6-hydroxylase ( Tagetes patula )
allocryptopine 6-hydroxylase / protopine-6-hydroxylase : CYP82N2v2 ( Eschscholzia californica )
flavonoid 3',5'-hydroxylase : AJ011862 ( Catharanthus roseus )
tyrosine N-monooxygenase : CYP79E1 ( Triglochin maritima )
triethylamine monooxygenase [multifunctional] ( Arthrobacter protophormiae R4 )
N-formyldemecolcine deformylase [multifunctional] ( Colchicum autumnale )
ent-kaurenoic acid NADPH:oxygen oxidoreductase ( Stevia rebaudiana )
α/β-amyrin 28-monooxygenase : CYP716AL1 ( Catharanthus roseus )
ursolic aldehyde 28-monooxygenase [multifunctional] : CYP716A15 ( Vitis vinifera )
β-amyrin 28-oxidase : CYP716A12 ( Medicago truncatula )
11-oxo-β-amyrin 30-oxidase : CYP72A154 ( Glycyrrhiza uralensis )
taxoid 7β-hydroxylase ( Taxus cuspidata )
taxoid 2α-hydroxylase ( Taxus cuspidata )
premithramycin B monooxygenase : mtmOIV ( Streptomyces argillaceus )
violaceinate synthase / deoxyviolaceinate synthase : vioC ( Chromobacterium violaceum )
protoviolaceinate synthase : vioD ( Chromobacterium violaceum )
cholesterol 7α-monooxygenase : CYP7A1 , POR ( Homo sapiens )
salicylate monooxygenase ( Pseudomonas nitroreducens )
2-hydroxybiphenyl-3-monooxygenase [multifunctional] : hbpA ( Pseudomonas nitroreducens )
3,6-diketocamphane 1,6-monooxygenase complex : Fred , camE36 ( Pseudomonas putida ATCC 17453 )
CYP79F2 monooxygenase : At1g16400 ( Arabidopsis thaliana col )
CYP79F1 monooxygenase : At1g16410 ( Arabidopsis thaliana col )
8,8a-deoxyoleandolide monooxygenase : oleP ( Streptomyces antibioticus )
dimethylamine monooxygenase ( Methylocella silvestris )
3-ketosteroid 9α-hydroxylase : kshB , kshA ( Mycobacterium tuberculosis )
3-ketosteroid 9α-hydroxylase complex : kshB , kshA ( Rhodococcus rhodochrous )
cholest-4-en-3-one 26-monooxygenase : cyp125 ( Mycobacterium tuberculosis )
cholest-4-en-3-one 26-monooxygenase : cyp125 ( Rhodococcus jostii RHA1 )
11α-hydroxy-β-amyrin dehydrogenase : CYP88D6 ( Glycyrrhiza uralensis )
pentalenene oxygenase : pntI ( Streptomyces arenae )
pentalenene oxygenase : ptlI ( Streptomyces avermitilis )
justicidin B 7-hydroxylase : JusB7H ( Linum perenne )
jasmonoyl-isoleucine-12-hydroxylase : CYP94B3 ( Arabidopsis thaliana col )
very long chain fatty acid ω-hydroxylase : CYP86B1 ( Arabidopsis thaliana col )
4-α-methyl-Δ7-sterol-4α-methyl oxidase : SMO2-1 ( Arabidopsis thaliana col )
4,4-dimethyl-9β,19-cyclopropylsterol-4α-methyl oxidase : SMO1-1 ( Arabidopsis thaliana col )
TMTT synthase / DMNT synthase : CYP82G1 ( Arabidopsis thaliana col )
pyocyanin hydroxylase [multifunctional] : phzS , phzM ( Pseudomonas aeruginosa )
β-phenylalanoyl baccatin III-2'-hydroxylase ( Taxus x media )
aminopyrrolnitrin oxygenase : prnD ( Pseudomonas protegens Pf-5 )
Δ12-linoleate epoxygenase : CYP726A1 ( Euphorbia lagascae )
farnesyl methyl ester epoxidase : CYP15A1 ( Diploptera punctata )
farnesyl methyl ester epoxidase ( Blaberus giganteus )
brassinolide synthase : CYP85A2 ( Arabidopsis thaliana col )
brassinosteroid-6-oxidase : CYP85A1 ( Arabidopsis thaliana col )
6-deoxotyphasterol C-23 hydroxylase [multifunctional] : CYP90D1 ( Arabidopsis thaliana col )
3-epi-6-deoxocathasterone C-23 hydroxylase [multifunctional] : CYP90C1 ( Arabidopsis thaliana col )
limonene hydroxylase : pOT435 ( Bacillus stearothermophilus BR388 )
perillyl aldehyde monooxygenase ( Pseudomonas sp. PL )
ferulate 5-hydroxylase : FAH1 ( Arabidopsis thaliana col )
elymoclavine monooxygenase : cloA ( Epichloe festucae )
elmoclavine monooxygenase : cloA ( Claviceps purpurea )
laurate hydroxylase : IMT-6 ( Petunia x hybrida )
laurate in-chain hydroxylase : CYP703A2 ( Arabidopsis thaliana col )
laurate ω-hydroxylase ( Pisum sativum )
laurate monooxygenase ( Helianthus tuberosus )
laurate monoxygenase : IMT-2 ( Petunia x hybrida )
lauric acid dehydroxylase : CYP76J1 ( Petunia x hybrida )
fatty acid ω-hydroxylase : CYP86A1 ( Arabidopsis thaliana col )
fatty acid ω-hydroxylase ( Glycine max )
palmitate-hydroxylase / oleate omega-hydroxylase : CYP704B2 ( Oryza sativa Japonica Group )
fatty acid ω-hydroxylase : CYP94C1 ( Arabidopsis thaliana col )
fatty acid ω-hydroxylase : CYP86A8 ( Arabidopsis thaliana col )
long-chain fatty acid ω-hydroxylase : CYP704B1 ( Arabidopsis thaliana col )
cytochrome P450 monooxygenase CYP52M1 : CYP52M1 ( Starmerella bombicola )
phenol 2-monooxygenase : GI:170525 ( Trichosporon cutaneum )
2,4-dichlorophenol 6-monooxygenase II : tfdBII ( Ralstonia eutropha JMP134 )
2,4-dichlorophenol 6-monooxygenase I : tfdBI ( Ralstonia eutropha JMP134 )
2,5-diketocamphane 1,2-monooxygenase complex : Fred , camE25-2 , camE25-1 ( Pseudomonas putida ATCC 17453 )
toluene monooxygenase / 4-nitrotoluene monooxygenase : ntnM , ntnA ( Pseudomonas putida TW3 )
resorcinol hydroxylase ( Pseudomonas putida ORC )
toluene ortho-monooxygenase : tomA4 , tomA1 , tomA3 , tomA5 , tomA2 ( Burkholderia cepacia )
toluene 3-monooxygenase : tbuU , tbuA2 , tbuA1 , tbuC , tbuV , tbuB ( Ralstonia pickettii )
3,5-xylenol methylhydroxylase ( Pseudomonas alcaligenes NCIMB 9867 )
2-octaprenylphenol hydroxylase : ubiI ( Escherichia coli K-12 substr. MG1655 )
2-octaprenyl-6-methoxyphenol hydroxylase : ubiH ( Escherichia coli K-12 substr. MG1655 )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, BIOCYC14A.