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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc EC 1.14.13 -- With NADH or NADPH as one donor, and incorporation of one atom of oxygen

Parent Class: EC-Numbers 1 -- Oxidoreductases 1.14 -- Acting on paired donors, with incorporation or reduction of molecular oxygen

Instances:
1.14.13.1 -- salicylate 1-monooxygenase ,
1.14.13.2 -- 4-hydroxybenzoate 3-monooxygenase ,
1.14.13.4 -- melilotate 3-monooxygenase ,
1.14.13.5 -- imidazoleacetate 4-monooxygenase ,
1.14.13.6 -- orcinol 2-monooxygenase ,
1.14.13.7 -- phenol 2-monooxygenase ,
1.14.13.8 -- flavin-containing monooxygenase ,
1.14.13.9 -- kynurenine 3-monooxygenase ,
1.14.13.10 -- 2,6-dihydroxypyridine 3-monooxygenase ,
1.14.13.11 -- trans-cinnamate 4-monooxygenase ,
1.14.13.12 -- benzoate 4-monooxygenase ,
1.14.13.13 -- calcidiol 1-monooxygenase ,
1.14.13.14 -- trans-cinnamate 2-monooxygenase ,
1.14.13.15 -- cholestanetriol 26-monooxygenase ,
1.14.13.16 -- cyclopentanone monooxygenase ,
1.14.13.17 -- cholesterol 7α-monooxygenase ,
1.14.13.18 -- 4-hydroxyphenylacetate 1-monooxygenase ,
1.14.13.19 -- taxifolin 8-monooxygenase ,
1.14.13.20 -- 2,4-dichlorophenol 6-monooxygenase ,
1.14.13.21 -- flavonoid 3′-monooxygenase ,
1.14.13.22 -- cyclohexanone monooxygenase ,
1.14.13.23 -- 3-hydroxybenzoate 4-monooxygenase ,
1.14.13.24 -- 3-hydroxybenzoate 6-monooxygenase ,
1.14.13.25 -- methane monooxygenase (soluble) ,
1.14.13.26 -- phosphatidylcholine 12-monooxygenase ,
1.14.13.27 -- 4-aminobenzoate 1-monooxygenase ,
1.14.13.28 -- 3,9-dihydroxypterocarpan 6a-monooxygenase ,
1.14.13.29 -- 4-nitrophenol 2-monooxygenase ,
1.14.13.30 -- leukotriene-B4 20-monooxygenase ,
1.14.13.31 -- 2-nitrophenol 2-monooxygenase ,
1.14.13.32 -- albendazole monooxygenase ,
1.14.13.33 -- 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] ,
1.14.13.34 -- leukotriene-E4 20-monooxygenase ,
1.14.13.35 -- anthranilate 3-monooxygenase (deaminating) ,
1.14.13.36 -- 5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase ,
1.14.13.37 -- methyltetrahydroprotoberberine 14-monooxygenase ,
1.14.13.38 -- anhydrotetracycline monooxygenase ,
1.14.13.39 -- nitric-oxide synthase (NADPH dependent) ,
1.14.13.40 -- anthraniloyl-CoA monooxygenase ,
1.14.13.41 -- tyrosine N-monooxygenase ,
1.14.13.43 -- questin monooxygenase ,
1.14.13.44 -- 2-hydroxybiphenyl 3-monooxygenase ,
1.14.13.46 -- (-)-menthol monooxygenase ,
1.14.13.47 -- (S)-limonene 3-monooxygenase ,
1.14.13.48 -- (S)-limonene 6-monooxygenase ,
1.14.13.49 -- (S)-limonene 7-monooxygenase ,
1.14.13.50 -- pentachlorophenol monooxygenase ,
1.14.13.51 -- 6-oxocineole dehydrogenase ,
1.14.13.52 -- isoflavone 3′-hydroxylase ,
1.14.13.53 -- 4′-methoxyisoflavone 2′-hydroxylase ,
1.14.13.54 -- ketosteroid monooxygenase ,
1.14.13.55 -- protopine 6-monooxygenase ,
1.14.13.56 -- dihydrosanguinarine 10-monooxygenase ,
1.14.13.57 -- dihydrochelirubine 12-monooxygenase ,
1.14.13.58 -- benzoyl-CoA 3-monooxygenase ,
1.14.13.59 -- L-lysine N6-monooxygenase (NADPH) ,
1.14.13.61 -- 2-hydroxyquinoline 8-monooxygenase ,
1.14.13.62 -- 4-hydroxyquinoline 3-monooxygenase ,
1.14.13.63 -- 3-hydroxyphenylacetate 6-hydroxylase ,
1.14.13.64 -- 4-hydroxybenzoate 1-hydroxylase ,
1.14.13.66 -- 2-hydroxycyclohexanone 2-monooxygenase ,
1.14.13.67 -- quinine 3-monooxygenase ,
1.14.13.68 -- 4-hydroxyphenylacetaldehyde oxime monooxygenase ,
1.14.13.69 -- alkene monooxygenase ,
1.14.13.70 -- sterol 14α-demethylase ,
1.14.13.71 -- N-methylcoclaurine 3′-monooxygenase ,
1.14.13.72 -- methylsterol monooxygenase ,
1.14.13.73 -- tabersonine 16-hydroxylase ,
1.14.13.74 -- 7-deoxyloganin 7-hydroxylase ,
1.14.13.75 -- vinorine hydroxylase ,
1.14.13.76 -- taxane 10β-hydroxylase ,
1.14.13.77 -- taxane 13α-hydroxylase ,
1.14.13.78 -- ent-kaurene oxidase ,
1.14.13.79 -- ent-kaurenoic acid oxidase ,
1.14.13.80 -- (R)-limonene 6-monooxygenase ,
1.14.13.81 -- magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase ,
1.14.13.82 -- vanillate monooxygenase ,
1.14.13.83 -- precorrin-3B synthase ,
1.14.13.84 -- 4-hydroxyacetophenone monooxygenase ,
1.14.13.85 -- glyceollin synthase ,
1.14.13.86 -- 2-hydroxyisoflavanone synthase ,
1.14.13.87 -- licodione synthase ,
1.14.13.88 -- flavanoid 3′,5′-hydroxylase ,
1.14.13.89 -- isoflavone 2′-hydroxylase ,
1.14.13.90 -- zeaxanthin epoxidase ,
1.14.13.91 -- deoxysarpagine hydroxylase ,
1.14.13.92 -- phenylacetone monooxygenase ,
1.14.13.93 -- (+)-abscisic acid 8′-hydroxylase ,
1.14.13.94 -- lithocholate 6β-hydroxylase ,
1.14.13.95 -- 7α-hydroxycholest-4-en-3-one 12α-hydroxylase ,
1.14.13.96 -- 5β-cholestane-3α,7α-diol 12α-hydroxylase ,
1.14.13.97 -- taurochenodeoxycholate 6α-hydroxylase ,
1.14.13.98 -- cholesterol 24-hydroxylase ,
1.14.13.99 -- 24-hydroxycholesterol 7α-hydroxylase ,
1.14.13.100 -- 25/26-hydroxycholesterol 7α-hydroxylase ,
1.14.13.101 -- senecionine N-oxygenase ,
1.14.13.102 -- psoralen synthase ,
1.14.13.103 -- 8-dimethylallylnaringenin 2′-hydroxylase ,
1.14.13.104 -- (+)-menthofuran synthase ,
1.14.13.105 -- monocyclic monoterpene ketone monooxygenase ,
1.14.13.106 -- epi-isozizaene 5-monooxygenase ,
1.14.13.107 -- limonene 1,2-monooxygenase ,
1.14.13.108 -- abieta-7,13-diene hydroxylase ,
1.14.13.109 -- abieta-7,13-dien-18-ol hydroxylase ,
1.14.13.110 -- geranylgeraniol 18-hydroxylase ,
1.14.13.111 -- methanesulfonate monooxygenase ,
1.14.13.112 -- 3-epi-6-deoxocathasterone 23-monooxygenase ,
1.14.13.113 -- FAD-dependent urate hydroxylase ,
1.14.13.114 -- 6-hydroxynicotinate 3-monooxygenase ,
1.14.13.115 -- angelicin synthase ,
1.14.13.116 -- geranylhydroquinone 3′′-hydroxylase ,
1.14.13.117 -- isoleucine N-monooxygenase ,
1.14.13.118 -- valine N-monooxygenase ,
1.14.13.119 -- 5-epiaristolochene 1,3-dihydroxylase ,
1.14.13.120 -- costunolide synthase ,
1.14.13.121 -- premnaspirodiene oxygenase ,
1.14.13.122 -- chlorophyllide-a oxygenase ,
1.14.13.123 -- germacrene A hydroxylase ,
1.14.13.124 -- phenylalanine N-monooxygenase ,
1.14.13.125 -- tryptophan N-monooxygenase ,
1.14.13.126 -- vitamin D3 24-hydroxylase ,
1.14.13.127 -- 3-(3-hydroxyphenyl)propanoate hydroxylase ,
1.14.13.128 -- 7-methylxanthine demethylase ,
1.14.13.129 -- β-carotene 3-hydroxylase ,
1.14.13.130 -- pyrrole-2-carboxylate monooxygenase ,
1.14.13.131 -- dimethyl-sulfide monooxygenase ,
1.14.13.132 -- squalene monooxygenase ,
1.14.13.133 -- pentalenene oxygenase ,
1.14.13.134 -- β-amyrin 11-oxidase ,
1.14.13.135 -- 1-hydroxy-2-naphthoate hydroxylase ,
1.14.13.136 -- 2-hydroxyisoflavanone synthase ,
1.14.13.137 -- indole-2-monooxygenase ,
1.14.13.138 -- indolin-2-one monooxygenase ,
1.14.13.139 -- 3-hydroxyindolin-2-one monooxygenase ,
1.14.13.140 -- 2-hydroxy-1,4-benzoxazin-3-one monooxygenase ,
1.14.13.141 -- cholest-4-en-3-one 26-monooxygenase ,
1.14.13.142 -- 3-ketosteroid 9α-monooxygenase ,
1.14.13.143 -- ent-isokaurene C2-hydroxylase ,
1.14.13.144 -- 9β-pimara-7,15-diene oxidase ,
1.14.13.145 -- ent-cassa-12,15-diene 11-hydroxylase ,
1.14.13.146 -- taxoid 14β-hydroxylase ,
1.14.13.147 -- taxoid 7β-hydroxylase ,
1.14.13.148 -- trimethylamine monooxygenase ,
1.14.13.149 -- phenylacetyl-CoA 1,2-epoxidase ,
1.14.13.150 -- α-humulene 10-hydroxylase ,
1.14.13.151 -- linalool 8-monooxygenase ,
1.14.13.152 -- geraniol 8-hydroxylase ,
1.14.13.153 -- (+)-sabinene 3-hydroxylase ,
1.14.13.154 -- erythromycin 12-hydroxylase ,
1.14.13.155 -- α-pinene monooxygenase ,
1.14.13.156 -- 1,8-cineole 2-endo-monooxygenase ,
1.14.13.157 -- 1,8-cineole 2-exo-monooxygenase ,
1.14.13.158 -- amorpha-4,11-diene 12-monooxygenase ,
1.14.13.159 -- vitamin D 25-hydroxylase ,
1.14.13.160 -- (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase ,
1.14.13.161 -- (+)-camphor 6-exo-hydroxylase ,
1.14.13.162 -- 2,5-diketocamphane 1,2-monooxygenase ,
1.14.13.163 -- 6-hydroxy-3-succinoylpyridine 3-monooxygenase ,
1.14.13.165 -- nitric-oxide synthase [NAD(P)H-dependent] ,
1.14.13.166 -- 4-nitrocatechol 4-monooxygenase ,
1.14.13.167 -- 4-nitrophenol 4-monooxygenase ,
1.14.13.168 -- indole-3-pyruvate monooxygenase ,
1.14.13.169 -- sphinganine C4-monooxygenase ,
1.14.13.170 -- pentalenolactone D synthase ,
1.14.13.171 -- neopentalenolactone D synthase ,
1.14.13.172 -- salicylate 5-hydroxylase ,
1.14.13.173 -- 11-oxo-β-amyrin 30-oxidase ,
1.14.13.174 -- averantin hydroxylase ,
1.14.13.175 -- aflatoxin B synthase ,
1.14.13.176 -- tryprostatin B 6-hydroxylase ,
1.14.13.177 -- fumitremorgin C monooxygenase ,
1.14.13.178 -- methylxanthine N1-demethylase ,
1.14.13.179 -- methylxanthine N3-demethylase ,
1.14.13.180 -- aklavinone 12-hydroxylase ,
1.14.13.181 -- 13-deoxydaunorubicin hydroxylase ,
1.14.13.182 -- 2-heptyl-3-hydroxy-4(1H)-quinolone synthase ,
1.14.13.183 -- dammarenediol 12-hydroxylase ,
1.14.13.184 -- protopanaxadiol 6-hydroxylase ,
1.14.13.185 -- pikromycin synthase ,
1.14.13.186 -- 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase ,
1.14.13.187 -- L-evernosamine nitrososynthase ,
1.14.13.188 -- 6-deoxyerythronolide B hydroxylase ,
1.14.13.189 -- 5-methyl-1-naphthoate 3-hydroxylase ,
1.14.13.190 -- ferruginol synthase ,
1.14.13.191 -- ent-sandaracopimaradiene 3-hydroxylase ,
1.14.13.192 -- oryzalexin E synthase ,
1.14.13.193 -- oryzalexin D synthase ,
1.14.13.194 -- phylloquinone ω-hydroxylase ,
1.14.13.cn -- β-amyrin 28-monooxygenase

Unofficial Reactions:
2-methoxy-6-(all-trans-octaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
2-octaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-octaprenyl)benzene-1,2-diol + NADP+ + H2O ,
3-methylphenol + NADH + oxygen + H+ → 3-hydroxybenzyl alcohol + NAD+ + H2O ,
linalool + NADH + H+ + oxygen → (6E)-8-hydroxylinalool + NAD+ + H2O ,
4-methylphenol + NADH + H+ + oxygen → 4-methylcatechol + NAD+ + H2O ,
2-methylphenol + NADH + H+ + oxygen → 3-methylcatechol + NAD+ + H2O ,
resorcinol + NADH + H+ + oxygen → 1,2,4-benzenetriol + NAD+ + H2O ,
4-nitrotoluene + NADH + H+ + oxygen → 4-nitrobenzyl alcohol + NAD+ + H2O ,
5-hydroxyadamantan-2-one + NADH + oxygen + H+ → 1-hydroxy-4-oxahomoadamantan-5-one + NAD+ + H2O ,
adamantanone + NADH + H+ + oxygen → 4-oxahomoadamantan-5-one + NAD+ + H2O ,
4-chlorophenol + NADPH + oxygen + H+ → 4-chlorocatechol + NADP+ + H2O ,
2-chlorophenol + NADPH + oxygen + H+ → 3-chlorocatechol + NADP+ + H2O ,
3-chlorophenol + NADPH + oxygen + H+ → 3-chlorocatechol + NADP+ + H2O ,
3-chlorophenol + NADPH + oxygen + H+ → 4-chlorocatechol + NADP+ + H2O ,
a jasmonic acid + NADPH + oxygen + H+ → a 12-hydroxyjasmonate + NADP+ + H2O ,
(-)-jasmonate + NADPH + oxygen + H+ → an 11-hydroxyjasmonate + NADP+ + H2O ,
palmitate + NADPH + H+ + oxygen → 16-hydroxypalmitate + NADP+ + H2O ,
16-hydroxypalmitate + NADPH + H+ + oxygen → 10,16-dihydroxypalmitate + NADP+ + H2O ,
oleate + NADPH + oxygen + H+ → 18-hydroxyoleate + NADP+ + H2O ,
laurate + NADPH + oxygen + H+ → ω-hydroxylaurate + NADP+ + H2O ,
decanoate + NADPH + oxygen + H+ → ω-hydroxycaprate + NADP+ + H2O ,
laurate + NADH + oxygen + H+ → ω-hydroxylaurate + NAD+ + H2O ,
laurate + NADPH + oxygen + H+ → ω-1 laurate + NADP+ + H2O ,
elymoclavine aldehyde + NADPH + oxygen → paspalate + NADP+ + H2O ,
agroclavine + NADPH + oxygen + H+ → elymoclavine + NADP+ + H2O ,
coniferaldehyde + NADPH + H+ + oxygen → 5-hydroxy-coniferaldehyde + NADP+ + H2O ,
(4R)-perillyl aldehyde + NADH + oxygen → (4R)-perillate + NAD+ + H2O ,
(4R)-limonene + NADH + oxygen + H+ → (4R)-perillyl alcohol + NAD+ + H2O ,
(22α)-hydroxy-campesterol + NADPH + H+ + oxygen → (22R,23R)-22,23-dihydroxycampesterol + NADP+ + H2O ,
(22α)-hydroxy-campest-4-en-3-one + NADPH + H+ + oxygen → (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP+ + H2O ,
3-epi-6-deoxocathasterone + NADPH + H+ + oxygen → 6-deoxotyphasterol + NADP+ + H2O ,
3-dehydro-6-deoxoteasterone + NADPH + oxygen → 3-dehydroteasterone + NADP+ + H+ + H2O ,
teasterone + NADPH + H+ + oxygen → 7-oxateasterone + NADP+ + H2O ,
typhasterol + NADPH + H+ + oxygen → 7-oxatyphasterol + NADP+ + H2O ,
(2E,6E)-farnesyl methyl ester + NADPH + oxygen + H+ → juvenile hormone III + NADP+ + H2O ,
1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + H+ + oxygen → 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP+ + H2O ,
(2-trans-6-trans)-farnesoate + NADPH + oxygen + H+ → juvenile hormone III acid + NADP+ + H2O ,
aminopyrrolnitrin + NAD(P)H + 2 oxygen + H+ → pyrrolnitrin + NAD(P)+ + 2 H2O ,
N-debenzoyl-(3'-RS)-2'-deoxytaxol + NADPH + oxygen + H+N-debenzoyl-(3'-RS)-taxol + NADP+ + H2O ,
5-methyl-phenazine-1-carboxylate + NADH + oxygen + 2 H+ → pyocyanin + CO2 + NAD+ + H2O ,
(3S,6E)-nerolidol + NADPH + H+ + oxygen → (3E)-4,8-dimethylnona-1,3,7-triene + but-1-en-3-one + NADP+ + 2 H2O ,
4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NADH + oxygen + H+ → 4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+ + 2 H2O ,
24-methylenecycloartanol + NADH + oxygen + H+ → 4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+ + H2O ,
4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NADH + oxygen → 4α-carboxy-4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+ + H2O ,
24-methylenelophenol + NADH + oxygen + H+ → 4α-hydroxymethyl-ergosta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl-ergosta-7,24(241)-dien-3β-ol + NADH + oxygen + H+ → 4α-formyl-ergosta-7,24(241)-dien-3β-ol + NAD+ + 2 H2O ,
4α-formyl-ergosta-7,24(241)-dien-3β-ol + NADH + oxygen → 4α-carboxy-ergosta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
24-ethylidenelophenol + NADH + oxygen + H+ → 4α-hydroxymethyl-stigmasta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl-stigmasta-7,24(241)-dien-3β-ol + NADH + oxygen + H+ → 4α-formyl-stigmasta-7,24(241)-dien-3β-ol + NAD+ + 2 H2O ,
4α-formyl-stigmasta-7,24(241)-dien-3β-ol + NADH + oxygen → 4α-carboxy-stigmasta-7,24(241)-dien-3β-ol + NAD+ + H2O ,
cycloartenol + NADH + oxygen + H+ → 4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NADH + oxygen + H+ → 4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD+ + 2 H2O ,
4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NADH + oxygen → 4α-carboxy,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD+ + H2O ,
4α-methyl-5α-cholesta-7,24-dien-3β-ol + NADH + oxygen + H+ → 4α-hydroxymethyl-5α-cholesta-7,24-dien-3β-ol + NAD+ + H2O ,
4α-hydroxymethyl-5α-cholesta-7,24-dien-3β-ol + NADH + oxygen + H+ → 4α-formyl-5α-cholesta-7,24-dien-3β-ol + NAD+ + 2 H2O ,
4α-formyl-5α-cholesta-7,24-dien-3β-ol + NADH + oxygen → 4α-carboxy-5α-cholesta-7,24-dien-3β-ol + NAD+ + H2O ,
behenate + NADPH + oxygen + H+ → 22-hydroxydocosanoate + NADP+ + H2O ,
a fatty acid + NADPH + oxygen + H+ → an in-chain hydroxy fatty acid + NADP+ + H2O ,
benzoate + NADPH + oxygen + H+ → 6-hydroxy-2-cyclohexen-one-carboxylate + NADP+ ,
(+)-7-iso-jasmonoyl-L-isoleucine + NADPH + oxygen + H+ → (3R, 7S)-12-hydroxy-jasmonoyl-L-isoleucine + NADP+ + H2O ,
justicidin B + NADPH + oxygen + H+ → diphyllin + NADP+ + H2O ,
(+)-α-santalene + NADPH + oxygen + H+ → (+)-α-santalol + NADP+ + H2O ,
kauralexin A1 + NADPH + oxygen → kauralexin A3 + NADP+ + H2O + H+ ,
kauralexin A3 + NADPH + oxygen → kauralexin A2 + NADP+ + H2O ,
ent-kaurene + NADPH + H+ + oxygen → kauralexin A1 + NADP+ + H2O ,
kauralexin B1 + NADPH + oxygen → kauralexin B3 + NADP+ + H2O + H+ ,
kauralexin B3 + NADPH + oxygen → kauralexin B2 + NADP+ + H2O ,
ent-isokaurene + NADPH + H+ + oxygen → kauralexin B1 + NADP+ + H2O ,
4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + NADPH + oxygen → zealexin A1 + NADP+ + H2O ,
pentalen-13-al + NADPH + oxygen → 1-deoxypentalenate + NADP+ + H2O ,
(S)-β-macrocarpene + NADPH + H+ + oxygen → [4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl] methanol + NADP+ + H2O ,
[4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl] methanol + NADPH + oxygen + H+ → 4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + NADP+ + 2 H2O ,
30-hydroxy-β-amyrin + NADPH + oxygen + H+ → 11α,30-dihydroxy-β-amyrin + NADP+ + H2O ,
cholesterol + NADH + oxygen + H+ → (25R)-cholest-5-ene-3β,26-diol + NAD+ + H2O ,
androst-4-ene-3,17-dione + NADH + oxygen + H+ → 9α-hydroxy-androst-4-en-3,17-dione + NAD+ + H2O ,
3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + NADH + oxygen + H+ → 9α-hydroxy-androst-4-en-3-one-17-propanoyl-CoA + NAD+ + H2O ,
3-one-23,24-bisnorchol-1,4-dien-22-yl-CoA + NADH + oxygen + H+ → 9α-hydroxy-3-oxo-23,24-bisnorchol-1,4-dien-22-yl-CoA + NAD+ + H2O ,
3-one-23,24-bisnorchol-4-en-22-oate + NADH + oxygen + H+ → 3-one-9-hydroxy-23,24-bisnorchol-4-en-22-oate + NAD+ + H2O ,
3-oxo-24-ethyl-cholest-4-ene + NADH + oxygen + H+ → 3-oxo-24-ethyl-26-hydroxy-cholest-4-ene + NAD+ + H2O ,
dimethylamine + NADPH + oxygen + H+ → methylamine + formaldehyde + NADP+ + H2O ,
8,8a-deoxyoleandolide + NADPH + oxygen → oleandolide + NADP+ + H2O + H+ ,
(6E)-8-hydroxylinalool + NADH + oxygen + H+ → (6E)-8-oxolinalool + NAD+ + 2 H2O ,
tetrahomomethionine + NADPH + oxygen → N-hydroxy-tetrahomomethionine + NADP+ + H2O ,
N-hydroxyhexahomomethioniate + NADPH + oxygen + H+N,N-dihydroxyhexahomomethioniate + NADP+ + H2O ,
pentahomomethionine + NADPH + oxygen → N-hydroxypentahomomethionine + NADP+ + H2O ,
N-hydroxypentahomomethionine + NADPH + oxygen + H+N,N-dihydroxypentahomomethionine + NADP+ + H2O ,
L-homomethionine + NADPH + oxygen → N-hydroxyhomomethionine + NADP+ + H2O ,
N-hydroxyhomomethionine + NADPH + oxygen + H+N,N-dihydroxyhomomethionine + NADP+ + H2O ,
L-dihomomethionine + NADPH + oxygen → N-hydroxy-L-dihomomethionine + NADP+ + H2O ,
N-hydroxy-L-dihomomethionine + NADPH + oxygen + H+N,N-dihydroxy-L-dihomomethionine + NADP+ + H2O ,
trihomomethionine + NADPH + oxygen → N-hydroxytrihomomethionine + NADP+ + H2O ,
N-hydroxytrihomomethionine + NADPH + oxygen + H+N, N-dihydroxytrihomomethionine + NADP+ + H2O ,
N, N-dihydroxytrihomomethionine + H+ = 6-methylthiohexanaldoxime + CO2 + H2O ,
N-hydroxy-tetrahomomethionine + NADPH + oxygen + H+N, N-dihydroxy-tetrahomomethionine + NADP+ + H2O ,
hexahomomethionine + NADPH + oxygen → N-hydroxyhexahomomethioniate + NADP+ + H2O ,
3,6-diketocamphane + NADH + H+ + oxygen → (-)-5-oxo-1,2-campholide + NAD+ + H2O ,
2-propylphenol + NADH + oxygen + H+ → 3-propylcatechol + NAD+ + H2O ,
2-isopropylphenol + NADH + oxygen + H+ → 3-isopropylcatechol + NAD+ + H2O ,
2,2',3-trihydroxybiphenyl + NADH + oxygen + H+ → 2,2',3,3'-tetrahydroxybiphenyl + NAD+ + H2O ,
2,3-dihydroxybenzoate + NADH + oxygen + 2 H+ → pyrogallol + CO2 + NAD+ + H2O ,
7-dehydrocholesterol + NADPH + H+ + oxygen → 7-ketocholesterol + NADP+ + H2O ,
protodeoxyviolaceinate + NADPH + oxygen + H+ → protoviolaceinate + NADP+ + H2O ,
protoviolaceinate + NADPH + oxygen + H+ → violaceinate + NADP+ + H2O ,
protodeoxyviolaceinate + NADPH + oxygen + H+ → deoxyviolaceinate + NADP+ + H2O ,
premithramycin B + NADPH + oxygen + H+ → premithramycin B lactone + NADP+ + H2O ,
elymoclavine + NADPH + oxygen + H+ → elymoclavine aldehyde + NADP+ + 2 H2O ,
taxusin + NADPH + oxygen + H+ → 2α-hydroxytaxusin + NADP+ + H2O ,
7β-hydroxytaxusin + NADPH + oxygen + H+ → 2α, 7β-dihydroxytaxusin + NADP+ + H2O ,
2α-hydroxytaxusin + NADPH + oxygen + H+ → 2α, 7β-dihydroxytaxusin + NADP+ + H2O ,
β-amyrin + NADPH + H+ + oxygen → 30-hydroxy-β-amyrin + NADP+ + H2O ,
lupeol + NADPH + oxygen + H+ → betulin + NADP+ + H2O ,
betulinic aldehyde + NADPH + oxygen + H+ → betulinate + NADP+ + H2O ,
α-amyrin + NADPH + oxygen + H+ → uvaol + NADP+ + H2O ,
ursolic aldehyde + NADPH + oxygen + H+ → ursolate + NADP+ + H2O ,
lupeol + 3 NADPH + 3 oxygen + 3 H+ → betulinate + 3 NADP+ + 4 H2O ,
α-amyrin + 3 NADPH + 3 oxygen + 3 H+ → ursolate + 3 NADP+ + 4 H2O ,
ent-kaur-16-en-19-oate + NADPH + oxygen + 2 H+ → steviol + NADP+ + H2O ,
O-methylandrocymbine + NADPH + oxygen → N-formyldemecolcine + NADP+ + H2O + 2 H+ ,
triethylamine + NADPH + oxygen → triethylamine N-oxide + NADP+ + H2O ,
diethylamine + NADPH + oxygen → diethylamine N-oxide + NADP+ + H2O ,
ethylamine + NADPH + H+ + oxygen → acetaldehyde + ammonium + NADP+ + H2O ,
4-hydroxyphenylacetonitrile + NADPH + oxygen + H+ → (R)-4-hydroxymandelonitrile + NADP+ + H2O ,
(+)-taxifolin + NADPH + oxygen + H+ → dihydromyricetin + NADP+ + H2O ,
allocryptopine + NADPH + oxygen + H+ → 6-hydroxy-allocryptopine + NADP+ + H2O ,
3,7,4'-trimethylquercetin + NADPH + oxygen + H+ → 2'-hydroxy 3,7,4'-trimethylquercetin + NADP+ + H2O ,
3,6,7,4'-tetramethylquercetagetin + NADPH + oxygen + H+ → 2'-hydroxy 3,6,7,4'-tetramethylquercetagetin + NADP+ + H2O ,
quercetin + NADPH + oxygen + H+ → quercetagetin + NADP+ + H2O ,
zeaxanthin + NADH + oxygen + H+ → caloxanthin + NAD+ + H2O ,
all-trans-β-carotene + 2 NADH + 2 H+ + 2 oxygen → (2R,2'R)-dihydroxy-all-trans-β-carotene + 2 NAD+ + 2 H2O ,
(2S)-naringenin + NADPH + oxygen → 2-hydroxynaringenin + NADP+ + H2O ,
eriodictyol + NADPH + oxygen + 2 H+ → 2-hydroxyeriodictyol + NADP+ + H2O ,
(2S)-pinocembrin + NADPH + oxygen + H+ → 2,5,7-trihydroxyflavanone + NADP+ + H2O ,
(Z)-2-methylbutanal oxime + NADPH + oxygen + H+ → 2-hydroxy-2-methylbutyronitrile + NADP+ + 2 H2O ,
chrysin + NADPH + oxygen + 2 H+ → baicalein + NADP+ + H2O ,
3-hexaprenyl-4-aminobenzoate + NADPH + oxygen + H+ → 3-hexaprenyl-4-amino-5-hydroxybenzoate + NADP+ + H2O ,
2-hexaprenyl-6-methoxyaminobenzene + NADPH + oxygen + H+ → 2-hexaprenyl-6-methoxyaminophenol + NADP+ + H2O ,
oleoyl-CoA + NADH + oxygen + H+ → ricinoleyl-CoA + NAD+ + H2O ,
(11Z)-eicos-11-enoyl-CoA + NADH + oxygen + H+ → lesqueroloyl-CoA + NAD+ + H2O ,
L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → (R)-β-hydroxy-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
β-oxo-L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → 2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
indole-3-acetate + NADH + oxygen + H+ → 2-hydroxy-indole-3-acetate + NAD+ + H2O ,
indole + NADH + oxygen + H+ → indoxyl + NAD+ + H2O ,
genkwanin + NADPH + oxygen + H+ → scutellarein 7-methyl ether + NADP+ + H2O ,
apigenin-7,4'-dimethyl ether + NADPH + oxygen + H+ → ladanein + NADP+ + H2O ,
(S)-sakuranetin + NADPH + oxygen + H+ → carthamidin-7-methyl ether + NADP+ + H2O ,
aurachin D + NADPH + oxygen + H+ → 9'-hydroxy-aurachin D + NADP+ + H2O ,
9'-hydroxy-aurachin D + NADPH + oxygen + H+ → aurachin RE + NADP+ + H2O ,
aurachin D + NADPH + oxygen + H+ → aurachin C + NADP+ + H2O ,
aurachin B + NAD(P)H + oxygen + H+ → aurachin B epoxide + NAD(P)+ + H2O ,
aurachin C + NAD(P)H + oxygen + H+ → aurachin C epoxide + NAD(P)+ + H2O ,
β-myrcene + NADPH + H+ + oxygen → (4S)-(+)-ipsdienol + NADP+ + H2O ,
β-myrcene + NADPH + H+ + oxygen → (4R)-(-)-ipsdienol + NADP+ + H2O ,
mycinamicin IV + NADPH + oxygen + H+ → mycinamicin V + NADP+ + H2O ,
mycinamicin V + NADPH + oxygen + H+ → mycinamicin II + NADP+ + H2O ,
mycinamicin IV + NADPH + oxygen + H+ → mycinamicin I + NADP+ + H2O ,
geraniol + NADPH + oxygen + H+ → 9-hydroxygeraniol + NADP+ + H2O ,
CMP-5'-3-aminopropylphosphonate + NADPH + oxygen → CMP-5'-N-hydroxy-3-aminopropylphosphonate + NADP+ + H2O ,
O-aminobenzaldehyde + NADH + oxygen → anthranilate + NAD+ + H2O ,
O-aminobenzaldehyde + NADPH + oxygen + H+ → anthranil + NADP+ + 2 H2O ,
O-aminobenzaldehyde + NADPH + oxygen → anthranilate + NADP+ + H2O ,
iridotrial + NADPH + oxygen → 7-deoxyloganetate + NADP+ + H2O ,
7-deoxyloganetin + NADPH + oxygen + H+ → loganetin + NADP+ + H2O ,
2-nonaprenylphenol + NADPH + oxygen + H+ → 2-(all-trans-nonaprenyl)benzene-1,4-diol + NADP+ + H2O ,
β-amyrin + NAD(P)H + oxygen + H+ → 12,13β-epoxy-β-amyrin + NAD(P)+ + H2O ,
12,13β-epoxy-β-amyrin + NAD(P)H + oxygen + H+ → 12,13β-epoxy-16β-hydroxy-β-amyrin + NAD(P)+ + H2O ,
β-amyrin + NAD(P)H + oxygen + H+ → 16β-hydroxy-β-amyrin + NAD(P)+ + H2O ,
16β-hydroxy-β-amyrin + NAD(P)H + oxygen + H+ → 12,13β-epoxy-16β-hydroxy-β-amyrin + NAD(P)+ + H2O ,
ent-sandaracopimaradiene + NADPH + H+ + oxygen → 7β-hydroxy-ent-sandaracopimaradiene + NADP+ + H2O ,
cyclooctat-9-en-5,7-diol + NADPH + oxygen + H+ → cyclooctatin + NADP+ + H2O ,
cyclooctat-9-en-7-ol + NADPH + oxygen + H+ → cyclooctat-9-en-5,7-diol + NADP+ + H2O ,
3β-hydroxy-12,15-cassadiene-11-one + NADPH + oxygen + H+ → 2β,3β-dihydroxy-12,15-cassadiene-11-one + NADP+ + H2O ,
7β-hydroxy-ent-sandaracopimaradiene + NADPH + oxygen + H+ → oryzalexin D + NADP+ + H2O ,
ent-cassa-12,15-diene + NADPH + oxygen + H+ → 3α-hydroxy-ent-cassadiene + NADP+ + H2O ,
(-)-9β-pimara-7,15-diene + NADPH + oxygen + H+ → 6β-hydroxy-syn-pimaradiene + NADP+ + H2O ,
1,3,7-trimethylurate + NADH + oxygen + 3 H+ → 1,3,7-trimethyl-5-hydroxyisourate + NAD+ + H2O ,
germacra-1(10),4,11(13)-trien-12-oate + NADPH + oxygen + H+ → 8β-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP+ + H2O ,
ent-cassa-12,15-diene + NADPH + oxygen + H+ → 2α-hydroxy-ent-cassadiene + NADP+ + H2O ,
3-methylphenol + NADPH + oxygen + H+ → 3-hydroxybenzyl alcohol + NADP+ + H2O ,
3-methylphenol + NADPH + oxygen + H+ → toluquinol + NADP+ + H2O ,
3-hydroxybenzyl alcohol + NADPH + H+ + oxygen → gentisyl alcohol + NADP+ + H2O ,
3-geranylgeranylindole + NADPH + oxygen + H+ → 10,11-epoxy-3-geranylgeranylindole + NADP+ + H2O ,
emindole-SB + NADPH + oxygen + H+ → 14,15-epoxyemindole-SB + NADP+ + H2O ,
paspaline + 4 NADPH + 4 oxygen + 4 H+ → β-10-hydroxy-12-demethyl-11,12-dehydropaspaline + formate + 4 NADP+ + 5 H2O + H+ ,
β-10-hydroxy-12-demethyl-11,12-dehydropaspaline + NADPH + oxygen + H+ → 13-desoxypaxilline + NADP+ + 2 H2O ,
13-desoxypaxilline + NADPH + oxygen + H+ → paxilline + NADP+ + H2O ,
(+)-costunolide + NADPH + oxygen + H+ → parthenolide + NADP+ + H2O ,
parthenolide + NADPH + oxygen + H+ → 3β-hydroxyparthenolide + NADP+ + H2O ,
(+)-costunolide + NADPH + oxygen + H+ → 3β-hydroxycostunolide + NADP+ + H2O ,
flaviolin + NADH + H+ + oxygen → mompain + NAD+ + H2O ,
fusicocca-2,10(14)-diene + NADPH + oxygen + H+ → fusicocca-2,10(14)-diene-8β-ol + NADP+ + H2O ,
fusicocca-2,10(14)-diene-8β-ol + NADPH + H+ + oxygen → fusicocca-2,10(14)-diene-8β,16-diol + NADP+ + H2O ,
4-sulfoacetophenone + NADPH + H+ + oxygen → 4-sulfophenyl acetate + NADP+ + H2O ,
a fatty acid + NADPH + oxygen + H+ → an (ω-1)-hydroxy fatty acid + NADP+ + H2O ,
paspaline + NADPH + oxygen + H+ = terpendole E + NADP+ + H2O ,
13-desoxypaxilline + NADPH + oxygen + H+ → paspalicine + NADP+ + 2 H2O ,
paspalicine + NADPH + oxygen + H+ → paspalinine + NADP+ + H2O ,
fumiquinazoline F + 2 NAD(P)H + 4 H+ + 2 oxygen → fumiquinazoline F-indoline-2,3-diol + 2 NAD(P)+ + 2 H2O ,
asperlicin C + NADH + H+ + oxygen → asperlicin E + NAD+ + H2O ,
α-cyclopiazonate + NAD(P)H + H+ + oxygen → 2-oxocyclopiazonate + NAD(P)+ + H2O ,
L-homomethionine + 2 NADPH + 2 oxygen + 2 H+ → 4-methylthiobutanaldoxime + CO2 + 2 NADP+ + 3 H2O ,
2-hydroxy-indole-3-acetate + NADH + oxygen + H+ → 3-hydroxy-2-oxo-indole-3-acetate + NAD+ + H2O ,
campesterol + NADPH + H+ + oxygen → (22α)-hydroxy-campesterol + NADP+ + H2O ,
(5α)-campestan-3-one + NADPH + H+ + oxygen → (22S,24R)-22-hydroxy-5α-ergostan-3-one + NADP+ + H2O ,
campest-4-en-3-one + NADPH + H+ + oxygen → (22α)-hydroxy-campest-4-en-3-one + NADP+ + H2O ,
an alkane + NADPH + oxygen + H+ → a long-chain alcohol + NADP+ + H2O ,
a fatty acid + NADPH + oxygen + H+ → an ω-hydroxy fatty acid + NADP+ + H2O ,
7-deoxyloganate + NADPH + H+ + oxygen → loganate + NADP+ + H2O ,
2-methylpropionitrile + NADPH + H+ + oxygen → acetone cyanohydrin + NADP+ + H2O ,
L-carnitine + NAD(P)H + oxygen + H+ → L-malic semialdehyde + trimethylamine + NAD(P)+ + H2O ,
dibenzothiophene + NADH + H+ + oxygen → dibenzothiophene-5-oxide + NAD+ + H2O ,
dibenzothiophene-5-oxide + NADH + H+ + oxygen → dibenzothiophene-5,5-dioxide + NAD+ + H2O ,
p-cymene + NADH + H+ + oxygen → p-cumic alcohol + NAD+ + H2O ,
6-oxocampestanol + NADPH + H+ + oxygen → cathasterone + NADP+ + H2O ,
castasterone + NADPH + H+ + oxygen → brassinolide + NADP+ + H2O ,
(2S)-naringenin + NADPH + oxygen → apigenin + NADP+ + 2 H2O ,
eriodictyol + NADPH + H+ + oxygen → luteolin + NADP+ + 2 H2O ,
6,7,4'-trihydroxyflavanone + NADPH + H+ + oxygen → 2,6,7,4'-tetrahydroxyisoflavanone + NADP+ + H2O ,
campestanol + NADPH + H+ + oxygen → 6-deoxocathasterone + NADP+ + H2O ,
a dihydroceramide + NADPH + oxygen + H+ → an α hydroxydihydroceramide + NADP+ + H2O ,
a dihydroceramide + NAD(P)H + oxygen + H+ → a phytoceramide + NAD(P)+ + H2O ,
sitosterol + NADPH + H+ + oxygen → (22α)-hydroxy-sitosterol + NADP+ + H2O ,
isofucosterol + NADPH + H+ + oxygen → (22α)-hydroxy-isofucosterol + NADP+ + H2O ,
cholestanol + NADPH + H+ + oxygen → (22α)-hydroxy-cholestanol + NADP+ + H2O ,
isoliquiritigenin + NADPH + H+ + oxygen → butein + NADP+ + H2O ,
β-amyrin + NADPH + H+ + oxygen → sophoradiol + NADP+ + H2O ,
24-hydroxy-β-amyrin + NADPH + H+ + oxygen → soyasapogenol B + NADP+ + H2O ,
(S)-cis-N-methylstylopine + NADPH + oxygen → protopine + NADP+ + H2O ,
abieta-7,13-diene-18-al + NADPH + oxygen → abieta-7,13-diene-18-oate + NADP+ + H2O ,
levopimaradiene + NADPH + H+ + oxygen → levopimaradienol + NADP+ + H2O ,
levopimaradienol + NADPH + H+ + oxygen → levopiramadiene-diol + NADP+ + H2O ,
levopimaradienal + NADPH + oxygen → levopimaric acid + NADP+ + H2O ,
neoabietadiene + NADPH + H+ + oxygen → neoabietadienol + NADP+ + H2O ,
neoabietadienol + NADPH + H+ + oxygen → neoabietadiene-diol + NADP+ + H2O ,
neoabietadienal + NADPH + oxygen → neoabietic acid + NADP+ + H2O ,
palustradiene + NADPH + H+ + oxygen → palustradienol + NADP+ + H2O ,
palustradienol + NADPH + H+ + oxygen → palustradiene-diol + NADP+ + H2O ,
palustradienal + NADPH + oxygen → palustric acid + NADP+ + H2O ,
dehydroabietadiene + NADPH + H+ + oxygen → dehydroabietadienol + NADP+ + H2O ,
dehydroabietadienol + NADPH + H+ + oxygen → dehydroabietadiene-diol + NADP+ + H2O ,
dehydroabietadienal + NADPH + oxygen → dehydroabietate + NADP+ + H2O ,
(+)-isopimara-7,15-diene + NADPH + H+ + oxygen → isopimaradienol + NADP+ + H2O ,
isopimaradienol + NADPH + H+ + oxygen → isopimaradiene-diol + NADP+ + H2O ,
isopimaradienal + NADPH + oxygen → isopimaric acid + NADP+ + H2O ,
(3R,6E)-nerolidol + NADPH + H+ + oxygen → (3E)-4,8-dimethylnona-1,3,7-triene + but-1-en-3-one + NADP+ + 2 H2O ,
(+)-pinoresinol + NADPH + H+ + oxygen → (+)-piperitol + NADP+ + 2 H2O ,
(+)-piperitol + NADPH + H+ + oxygen → (+)-sesamin + NADP+ + 2 H2O ,
tryptamine + NAD(P)H + H+ + oxygen → serotonin + NAD(P)+ + H2O ,
deoxypodophyllotoxin + NADPH + H+ + oxygen → β-peltatin + NADP+ + H2O ,
(+)-δ-cadinene + NADPH + H+ + oxygen → 8-hydroxy-(+)-δ-cadinene + NADP+ + H2O ,
2-heptaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-heptaprenyl)benzene-1,2-diol + NADP+ + H2O ,
2-methoxy-6-(all-trans-heptaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-heptaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol + NADPH + oxygen + H+ → 3-demethylubiquinol-7 + NADP+ + H2O ,
2-decaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-decaprenyl)benzene-1,2-diol + NADP+ + H2O ,
2-methoxy-6-(all-trans-decaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-decaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
2-nonaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-nonaprenyl)benzene-1,2-diol + NADP+ + H2O ,
3-octaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + NADP+ + H2O ,
3-nonaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-nonaprenylbenzoate + NADP+ + H2O ,
3-decaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + NADP+ + H2O ,
3-heptaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + NADP+ + H2O ,
(6E)-8-oxogeranial + NADPH + oxygen + H+ → iridotrial + NADP+ + H2O ,
a limonene + NADPH + H+ + oxygen → a limonene-1,2-epoxide + NADP+ + H2O ,
(4S)-limonene + NADPH + oxygen + H+ → (-)-cis-carveol + NADP+ + H2O ,
thalianol + NAD(P)H + oxygen → a thalian-diol + NAD(P)+ + H2O ,
2-methylbutyronitrile + NADPH + H+ + oxygen → 2-hydroxy-2-methylbutyronitrile + NADP+ + H2O ,
linoleate + NAD(P)H + oxygen + H+ → (+)-vernolate + NAD(P)+ + H2O ,
dimethyl sulfide + NADPH + oxygen + H+ → dimethyl sulfoxide + NADP+ + H2O ,
dimethyl sulfoxide + NADPH + oxygen + H+ → dimethyl sulfone + NADP+ + H2O ,
9,10-epoxystearate + NADPH + H+ + oxygen → 9,10-epoxy-18-hydroxystearate + NADP+ + H2O ,
(9R,10S)-dihydroxystearate + NADPH + H+ + oxygen → 9,10,18-trihydroxystearate + NADP+ + H2O ,
2-chloro-4-methylphenol + NADPH + oxygen + H+ → 3-chloro-5-methylcatechol + NADP+ + H2O ,
3-chlorotoluene + NADH + H+ + oxygen → 3-chlorobenzyl alcohol + NAD+ + H2O ,
a [protein chain elongation factor EF-P]-L-lysine34 + NADPH + oxygen + H+ → a [protein chain elongation factor EF-P]-5-hydroxy-L-lysine34 + NADP+ + H2O ,
2-hexaprenyl-6-methoxyphenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-hexaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
3-hexaprenyl-4-hydroxybenzoate + NADPH + oxygen + H+ → 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + NADP+ + H2O ,
cis-abscisic alcohol + NAD(P)+ + oxygen → 2-cis-abscisate + NAD(P)H + H2O ,
trans-abscisic alcohol + NAD(P)+ + oxygen → 2-trans-abscisate + NAD(P)H + H2O ,
17-α-hydroxyprogesterone + NADPH + H+ + oxygen → 11-desoxycortisol + NADP+ + H2O ,
progesterone + NADPH + H+ + oxygen → 11-deoxycorticosterone + NADP+ + H2O ,
L-dihomomethionine + 2 NADPH + 2 oxygen + 2 H+ → 5-methylthiopentanaldoxime + CO2 + 2 NADP+ + 3 H2O ,
trihomomethionine + 2 NADPH + 2 oxygen + 2 H+ → CO2 + 6-methylthiohexanaldoxime + 2 NADP+ + 3 H2O ,
tetrahomomethionine + 2 NADPH + 2 H+ + 2 oxygen → CO2 + 7-methylthioheptanaldoxime + 2 NADP+ + 3 H2O ,
pentahomomethionine + 2 NADPH + 2 oxygen + 2 H+ → 8-methylthiooctanaldoxime + CO2 + 2 NADP+ + 3 H2O ,
hexahomomethionine + 2 NADPH + 2 oxygen + 2 H+ → CO2 + 9-methylthiononanaldoxime + 2 NADP+ + 3 H2O ,
toluene + NADH + H+ + oxygen → 2-methylphenol + NAD+ + H2O ,
toluene + NADH + H+ + oxygen → 4-methylphenol + NAD+ + H2O ,
toluene + a reduced electron acceptor + oxygen → 4-methylphenol + an oxidized electron acceptor + H2O ,
toluene + NADH + H+ + oxygen → benzyl alcohol + NAD+ + H2O ,
zeaxanthin + 2 NADH + 2 H+ + 2 oxygen → nostoxanthin + 2 NAD+ + 2 H2O ,
mycinamicin VIII + NADPH + oxygen + H+ → mycinamicin VII + NADP+ + H2O ,
5-O-β-mycaminosyltylactone + NADPH + oxygen + H+ → 20-hydroxy-5-O-mycaminosyltylactone + NADP+ + H2O ,
cyclo(L-Phe-L-Ser) + 2 NAD(P)H + 2 H+ + 2 oxygen → 3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine + 2 NAD(P)+ + 2 H2O

Enzymes and Genes:
cyclo(L-Phe-L-Ser) hydroxylase : gliC ( Aspergillus fumigatus )
5-O-mycaminosyltylactone C20-hydroxylase : tylI ( Streptomyces fradiae )
mycinamicin VIII monooxygenase complex : mycCII , mycCI ( Micromonospora griseorubida )
toluene-4-monooxygenase : tmoA , tmoB , tmoE , tmoD , tmoC , tmoF ( Pseudomonas mendocina (pWWO) or (pTOL) )
steroid 21-monooxygenase : CYP21A2 ( Homo sapiens )
EF-P-Lys34 hydroxylase : epmC ( Escherichia coli K-12 substr. MG1655 )
xylene monooxygenase : xylA , xylM ( Pseudomonas putida mt-2 )
trimethylamine monooxygenase : tmm ( Methylocella silvestris )
dimethylsulfoxide oxygenase : dsoA , dsoB , dsoC , dsoD , dsoE , dsoF ( Acinetobacter sp. strain 20B )
CYP77A4 : AT5G04660 ( Arabidopsis thaliana col )
linoleate epoxygenase (cytochrome P450) ( Euphorbia lagascae )
Δ12 linoleate epoxygenase (fatty acid desaturase-like) : Cpal2 ( Crepis palaestina )
thalianol hydroxylase : THAH ( Arabidopsis thaliana col )
ubiquinone biosynthesis monooxygenase COQ6 : COQ6 ( Homo sapiens )
(+)-δ-cadinene-8-hydroxylase : CYP706B1 ( Gossypium arboreum )
deoxypodophyllotoxin 6-hydroxylase ( Linum flavum )
tryptamine 5-hydroxylase ( Juglans regia )
(+)-piperitol/(+)-sesamin synthase : CYP81Q2 ( Sesamum radiatum )
(+)-piperitol/(+)-sesamin synthase : CYP81Q1 ( Sesamum indicum )
abietadienol hydroxylase : CYP720B1 ( Pinus taeda )
(S)-cis-N-methylstylopine 14-hydroxylase/(S)-N-methylcanadine 14-hydroxylase : CYP82N4 ( Papaver somniferum )
(S)-cis-N-methylstylopine 14-hydroxylase/(S)-N-methylcanadine 14-monooxygenase ( Corydalis vaginans )
chalcone 3-hydroxylase ( Dahlia pinnata )
sphingolipid long-chain base 4-hydroxylase ( Zea mays )
sphingolipid very long chain fatty acid α-hydroxylase : AT2G34770 ( Arabidopsis thaliana col )
isoflavone synthase : IFS-Tp ( Trifolium pratense )
isoflavone synthase : IFS1 ( Glycine max )
isoflavone synthase : CYP Ge-8 ( Glycyrrhiza echinata )
apigenin synthase : CYP93B23 ( Ocimum basilicum )
flavone synthase II : CYP93B2 ( Gerbera hybrid cultivar )
brassinolide synthase : CYP85A3 ( Solanum lycopersicum )
p-cymene monooxygenase : cymAa , cymAb ( Pseudomonas putida F1 )
dibenzothiophene monooxygenase : dszC ( Rhodococcus YH3-3 )
carnitine monooxygenase complex : cntB , cntA ( Acinetobacter baumannii ATCC 19606 = CIP 70.34 )
carnitine monooxygenase ( Acinetobacter calcoaceticus )
n-alkane monooxygenase system : NCP1 , CYP52A3-A ( Candida maltosa )
steroid 22α-hydroxylase : CYP90B1 ( Arabidopsis thaliana col )
2-hydroxy-indole-3-acetate monooxygenase : iacE ( Pseudomonas putida 1290 )
α-cyclopiazonate hydroxylase : CpaH ( Aspergillus oryzae )
asperlicin C monooxygenase : AspB ( Aspergillus alliaceus )
fumiquinazoline F monooxygenase : Af12060 ( Aspergillus fumigatus )
cytochrome P450 monooxygenase, AtmQ : atmQ ( Aspergillus flavus )
cytochrome P450 monooxygenase, TerQ : terQ ( Tolypocladium album )
4-sulfoacetophenone monooxygenase : CtesDRAFT_PD5437 ( Comamonas testosteroni KF-1 )
fusicoccadiene 8-ol C-16 hydroxylase : fc8,16h ( Alternaria brassicicola ATCC 96836 )
fusicoccadiene C-8 hydroxylase : fc8h ( Alternaria brassicicola ATCC 96836 )
1,3,6,8-tetrahydroxynaphthalene monooxygenase : MomA ( Streptomyces antibioticus )
sesquiterpenoid 3β-hydroxylase : CYP71CB1 ( Tanacetum parthenium )
parthenolide synthase : CYP71CA1 ( Tanacetum parthenium )
cytochrome P450 monooxygenase, PaxQ : paxQ ( Penicillium paxilli ATCC 26601 )
multifunctional cytochrome P450 monooxygenase, AtmP : atmP ( Aspergillus flavus )
multifunctional cytochrome P450 monooxygenase, PaxP : paxP ( Penicillium paxilli ATCC 26601 )
FAD-dependent monooxygenase, PaxM : paxM ( Penicillium paxilli ATCC 26601 )
cytochrome P450 CYP619C2 : patI ( Aspergillus clavatus NRRL 1980 )
cytochrome P450 CYP619C3 : patH ( Aspergillus clavatus NRRL 1980 )
germacrene A acid 8β-hydroxylase : CYP71BL1 ( Helianthus annuus )
trimethyluric acid monooxygenase : tmuM ( Pseudomonas sp. CBB1 )
cytochrome P450 dependent diterpene olefin hydroxylase : KOL4 ( Oryza sativa )
ent-cassadiene-C2-hydroxylase : CYP71Z7 ( Oryza sativa )
octat-9-en-7-ol 5-monooxygenase : cotB3 ( Streptomyces melanosporofaciens )
cyclooctat-9-en-5,7-diol C18-monooxygenase : cotB4 ( Streptomyces melanosporofaciens )
cytochrome P450 dependent ent-sandaracopimardiene 9β-hydroxylase : CYP76M6 ( Oryza sativa )
cytochrome P450 dependent ent-sandaracopimardiene 7β-hydroxylase : CYP76M8 ( Oryza sativa )
cytochrome P450 dependent β-amyrin monooxygenase : SAD2 ( Avena strigosa )
CMP-5'-3-aminopropylphosphonate hydroxylase : frbG ( Streptomyces rubellomurinus )
mycinamicin IV hydroxylase/epoxidase : mycG ( Micromonospora griseorubida )
myrcene hydroxylase : CYP9T3 ( Ips pini )
myrcene hydroxylase : CYP9T2 ( Ips pini )
aurachin C monooxygenase : auaG ( Stigmatella aurantiaca Sg a15 )
aurachin B monooxygenase : auaJ ( Stigmatella aurantiaca Sg a15 )
aurachin D N-monooxygenase : auaF ( Stigmatella aurantiaca Sg a15 )
9'-hydroxy-aurachin D monooxygenase : rauA ( Rhodococcus erythropolis JCM 6824 )
flavone-6-hydroxylase : CYP82D62 ( Mentha x piperita )
genkwanin 6-hydroxylase : CYP82D33 ( Ocimum basilicum )
cytochrome P450 2E1 : CYP2E1 ( Homo sapiens )
indole monooxygenase : idoA ( Pseudomonas alcaligenes PA-10 )
indole monooxygenase / indole-3-acetate monooxygenase : iacA ( Pseudomonas putida 1290 )
L-tyrosine-[NovH-protein] β-hydroxylase : novI ( Actinoalloteichus cyanogriseus )
oleate 12-hydroxylase : AH12 ( Physaria lindheimeri )
oleate 12-hydroxylase:desaturase : AH12 ( Physaria fendleri )
oleate 12-hydroxylase : FAH12 ( Ricinus communis )
oleate 12-hydroxylase : FAH12 ( Ricinus communis )
3-hexaprenyl-benzoate-5-monoxygenase : COQ6 ( Saccharomyces cerevisiae )
CYP71E7 : CYP71E7 ( Manihot esculenta )
flavanone 2-hydroxylase : CYP93G2 ( Oryza sativa )
zeaxanthin 2,2'-β-hydroxylase : crtG ( Sphingomonas elodea )
flavonol 6-hydroxylase ( Rudbeckia hirta )
flavonol 6-hydroxylase ( Tagetes erecta )
flavonol 6-hydroxylase ( Tagetes patula )
allocryptopine 6-hydroxylase / protopine-6-hydroxylase : CYP82N2v2 ( Eschscholzia californica )
flavonoid 3',5'-hydroxylase : AJ011862 ( Catharanthus roseus )
tyrosine N-monooxygenase : CYP79E1 ( Triglochin maritima )
triethylamine monooxygenase [multifunctional] ( Arthrobacter protophormiae R4 )
N-formyldemecolcine deformylase [multifunctional] ( Colchicum autumnale )
ent-kaurenoic acid NADPH:oxygen oxidoreductase ( Stevia rebaudiana )
α/β-amyrin 28-monooxygenase : CYP716AL1 ( Catharanthus roseus )
ursolic aldehyde 28-monooxygenase [multifunctional] : CYP716A15 ( Vitis vinifera )
β-amyrin 28-oxidase : CYP716A12 ( Medicago truncatula )
11-oxo-β-amyrin 30-oxidase : CYP72A154 ( Glycyrrhiza uralensis )
taxoid 7β-hydroxylase ( Taxus cuspidata )
taxoid 2α-hydroxylase ( Taxus cuspidata )
premithramycin B monooxygenase : mtmOIV ( Streptomyces argillaceus )
violaceinate synthase / deoxyviolaceinate synthase : vioC ( Chromobacterium violaceum )
protoviolaceinate synthase : vioD ( Chromobacterium violaceum )
cholesterol 7α-monooxygenase : CYP7A1 , POR ( Homo sapiens )
salicylate monooxygenase ( Pseudomonas nitroreducens )
2-hydroxybiphenyl-3-monooxygenase [multifunctional] : hbpA ( Pseudomonas nitroreducens )
3,6-diketocamphane 1,6-monooxygenase complex : Fred , camE36 ( Pseudomonas putida ATCC 17453 )
CYP79F2 monooxygenase : At1g16400 ( Arabidopsis thaliana col )
CYP79F1 monooxygenase : At1g16410 ( Arabidopsis thaliana col )
8,8a-deoxyoleandolide monooxygenase : oleP ( Streptomyces antibioticus )
dimethylamine monooxygenase ( Methylocella silvestris )
3-ketosteroid 9α-hydroxylase : kshB , kshA ( Mycobacterium tuberculosis )
3-ketosteroid 9α-hydroxylase complex : kshB , kshA ( Rhodococcus rhodochrous )
cholest-4-en-3-one 26-monooxygenase : cyp125 ( Mycobacterium tuberculosis )
cholest-4-en-3-one 26-monooxygenase : cyp125 ( Rhodococcus jostii RHA1 )
11α-hydroxy-β-amyrin dehydrogenase : CYP88D6 ( Glycyrrhiza uralensis )
pentalenene oxygenase : pntI ( Streptomyces arenae )
pentalenene oxygenase : ptlI ( Streptomyces avermitilis )
justicidin B 7-hydroxylase : JusB7H ( Linum perenne )
jasmonoyl-isoleucine-12-hydroxylase : CYP94B3 ( Arabidopsis thaliana col )
very long chain fatty acid ω-hydroxylase : CYP86B1 ( Arabidopsis thaliana col )
4-α-methyl-Δ7-sterol-4α-methyl oxidase : SMO2-1 ( Arabidopsis thaliana col )
4,4-dimethyl-9β,19-cyclopropylsterol-4α-methyl oxidase : SMO1-1 ( Arabidopsis thaliana col )
TMTT synthase / DMNT synthase : CYP82G1 ( Arabidopsis thaliana col )
pyocyanin hydroxylase [multifunctional] : phzS , phzM ( Pseudomonas aeruginosa )
β-phenylalanoyl baccatin III-2'-hydroxylase ( Taxus x media )
aminopyrrolnitrin oxygenase : prnD ( Pseudomonas protegens Pf-5 )
Δ12-linoleate epoxygenase : CYP726A1 ( Euphorbia lagascae )
farnesyl methyl ester epoxidase : CYP15A1 ( Diploptera punctata )
farnesyl methyl ester epoxidase ( Blaberus giganteus )
brassinolide synthase : CYP85A2 ( Arabidopsis thaliana col )
brassinosteroid-6-oxidase : CYP85A1 ( Arabidopsis thaliana col )
6-deoxotyphasterol C-23 hydroxylase [multifunctional] : CYP90D1 ( Arabidopsis thaliana col )
3-epi-6-deoxocathasterone C-23 hydroxylase [multifunctional] : CYP90C1 ( Arabidopsis thaliana col )
limonene hydroxylase : pOT435 ( Bacillus stearothermophilus BR388 )
perillyl aldehyde monooxygenase ( Pseudomonas sp. PL )
ferulate 5-hydroxylase : FAH1 ( Arabidopsis thaliana col )
elymoclavine monooxygenase : cloA ( Epichloe festucae )
elmoclavine monooxygenase : cloA ( Claviceps purpurea )
laurate hydroxylase : IMT-6 ( Petunia x hybrida )
laurate in-chain hydroxylase : CYP703A2 ( Arabidopsis thaliana col )
laurate ω-hydroxylase ( Pisum sativum )
laurate monooxygenase ( Helianthus tuberosus )
laurate monoxygenase : IMT-2 ( Petunia x hybrida )
lauric acid dehydroxylase : CYP76J1 ( Petunia x hybrida )
fatty acid ω-hydroxylase : CYP86A1 ( Arabidopsis thaliana col )
fatty acid ω-hydroxylase ( Glycine max )
palmitate-hydroxylase / oleate omega-hydroxylase : CYP704B2 ( Oryza sativa Japonica Group )
fatty acid ω-hydroxylase : CYP94C1 ( Arabidopsis thaliana col )
fatty acid ω-hydroxylase : CYP86A8 ( Arabidopsis thaliana col )
long-chain fatty acid ω-hydroxylase : CYP704B1 ( Arabidopsis thaliana col )
cytochrome P450 monooxygenase CYP52M1 : CYP52M1 ( Starmerella bombicola )
phenol 2-monooxygenase : GI:170525 ( Trichosporon cutaneum )
2,4-dichlorophenol 6-monooxygenase II : tfdBII ( Ralstonia eutropha JMP134 )
2,4-dichlorophenol 6-monooxygenase I : tfdBI ( Ralstonia eutropha JMP134 )
2,5-diketocamphane 1,2-monooxygenase complex : Fred , camE25-2 , camE25-1 ( Pseudomonas putida ATCC 17453 )
toluene monooxygenase / 4-nitrotoluene monooxygenase : ntnM , ntnA ( Pseudomonas putida TW3 )
resorcinol hydroxylase ( Pseudomonas putida ORC )
toluene ortho-monooxygenase : tomA4 , tomA1 , tomA3 , tomA5 , tomA2 ( Burkholderia cepacia )
toluene 3-monooxygenase : tbuU , tbuA2 , tbuA1 , tbuC , tbuV , tbuB ( Ralstonia pickettii )
3,5-xylenol methylhydroxylase ( Pseudomonas alcaligenes NCIMB 9867 )
2-octaprenylphenol hydroxylase : ubiI ( Escherichia coli K-12 substr. MG1655 )
2-octaprenyl-6-methoxyphenol hydroxylase : ubiH ( Escherichia coli K-12 substr. MG1655 )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Dec 22, 2014, BIOCYC14B.