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MetaCyc EC 1.14.14 -- With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

Parent Class: EC-Numbers 1 -- Oxidoreductases 1.14 -- Acting on paired donors, with incorporation or reduction of molecular oxygen

Instances:
1.14.14.1 -- unspecific monooxygenase ,
1.14.14.3 -- alkanal monooxygenase (FMN) ,
1.14.14.5 -- alkanesulfonate monooxygenase ,
1.14.14.8 -- anthranilate 3-monooxygenase (FAD) ,
1.14.14.9 -- 4-hydroxyphenylacetate 3-monooxygenase ,
1.14.14.10 -- nitrilotriacetate monooxygenase ,
1.14.14.11 -- styrene monooxygenase ,
1.14.14.12 -- 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase ,
1.14.14.13 -- 4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase ,
1.14.14.14 -- aromatase ,
1.14.14.15 -- (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase

Unofficial Reactions:
4-coumarate + FADH2 + oxygen → trans-caffeate + FAD + H2O + H+ ,
dimethyl sulfone + 2 FMNH2 + 2 oxygen → methanesulfonate + formaldehyde + 2 FMN + 2 H2O + 3 H+ ,
3,5,6-trichloro-2-pyridinol + FADH2 + oxygen + 2 H2O → 3,6-dihydroxypyridine-2,5-dione + 3 chloride + FAD + H2O + 4 H+ ,
2-methylpropanamine + a reduced flavin + oxygen → N-(2-methylpropyl)hydroxylamine + an oxidized flavin + H2O + H+ ,
2,4,5-trichlorophenol + FADH2 + oxygen → 2,5-dichloro-p-quinone + chloride + FAD + H2O + H+ ,
4-tyrosol + FADH2 + oxygen → 3-hydroxytyrosol + FAD + H2O + H+ ,
dibenzothiophene-5,5-dioxide + 2 FMNH2 + oxygen → 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O + 3 H+ ,
2,6-dichloro-p-hydroquinone + 2 FADH2 + oxygen → 6-chlorohydroxyquinol + chloride + 2 FAD + H2O + 2 H+ ,
3-dehydro-2,22,25-deoxyecdysone + a reduced flavoprotein + oxygen → 3-dehydro-2,22-dideoxyecdysone + an oxidized flavoprotein + H2O ,
dimethyl sulfone + FMNH2 + oxygen → methylsulfonyl + formaldehyde + FMN + H2O + H+ ,
N'-hydroxymethyl-norcotinine + a reduced flavoprotein + oxygen → norcotinine + an oxidized flavoprotein + H2O ,
2,5-dichloro-p-quinol + FADH2 + oxygen → 5-chlorohydroxyquinone + chloride + FAD + H2O + 3 H+ ,
2,22,25-trideoxyecdysone + a reduced flavoprotein + oxygen → 2,22-dideoxyecdysone + an oxidized flavoprotein + H2O ,
(S)-β-tyrosyl-[SgcC2] + chloride + FADH2 + oxygen → (S)-3-chloro-β-tyrosyl-[SgcC2] + FAD + 2 H2O ,
L-tyrosine + FADH2 + oxygen → L-dopa + FAD + H2O + H+ ,
20-hydroxyecdysone + 3 a reduced flavoprotein + 3 oxygen → 20-hydroxyecdysonate + 3 an oxidized flavoprotein + 4 H2O + H+ ,
8-demethylnovobiocic acid + chloride + FADH2 + oxygen → clorobiocic acid + FAD + 2 H2O

Enzymes and Genes:
8-demethylnovobiocic acid halogenase : clo-hal ( Streptomyces roseochromogenus oscitans )
cytochrome P450 18a1 : Cyp18a1 ( Drosophila melanogaster )
cytochrome P450 306a1 : phm ( Bombyx mori )
cytochrome P450 306a1 : phm ( Drosophila melanogaster )
cytochrome P450 306A1 : phm ( Manduca sexta )
2,4,6-trichlorophenol monooxygenase / 2,6-dichlorohydroquinone monooxygenase : tcpA ( Ralstonia eutropha JMP134 )
dibenzothiophene-5,5-dioxide monooxygenase : dszA ( Rhodococcus YH3-3 )
chlorophenol-4-monooxygenase : tftD ( Burkholderia phenoliruptrix )
isobutylamine N-hydroxylase : vlmH ( Streptomyces viridifaciens )
3,5,6-trichloro-2-pyridinol monooxygenase : tcpA ( Ralstonia sp. T6 )
dimethylsulfone monooxygenase : sfnG ( Pseudomonas putida DS1 )
4-coumarate 3-monooxygenase : hpaB ( Escherichia coli W )


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Sep 1, 2015, biocyc13.