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MetaCyc EC 2.1.1 -- Methyltransferases

Parent Class: EC-Numbers2 -- Transferases2.1 -- Transferring one-carbon groups

Instances:
2.1.1.1 -- nicotinamide N-methyltransferase,
2.1.1.2 -- guanidinoacetate N-methyltransferase,
2.1.1.3 -- thetin—homocysteine S-methyltransferase,
2.1.1.4 -- acetylserotonin O-methyltransferase,
2.1.1.5 -- betaine—homocysteine S-methyltransferase,
2.1.1.6 -- catechol O-methyltransferase,
2.1.1.7 -- nicotinate N-methyltransferase,
2.1.1.8 -- histamine N-methyltransferase,
2.1.1.9 -- thiol S-methyltransferase,
2.1.1.10 -- homocysteine S-methyltransferase,
2.1.1.11 -- magnesium protoporphyrin IX methyltransferase,
2.1.1.12 -- methionine S-methyltransferase,
2.1.1.13 -- methionine synthase,
2.1.1.14 -- 5-methyltetrahydropteroyltriglutamate—homocysteine S-methyltransferase,
2.1.1.15 -- fatty-acid O-methyltransferase,
2.1.1.16 -- methylene-fatty-acyl-phospholipid synthase,
2.1.1.17 -- phosphatidylethanolamine N-methyltransferase,
2.1.1.18 -- polysaccharide O-methyltransferase,
2.1.1.19 -- trimethylsulfonium—tetrahydrofolate N-methyltransferase,
2.1.1.20 -- glycine N-methyltransferase,
2.1.1.21 -- methylamine—glutamate N-methyltransferase,
2.1.1.22 -- carnosine N-methyltransferase,
2.1.1.25 -- phenol O-methyltransferase,
2.1.1.26 -- iodophenol O-methyltransferase,
2.1.1.27 -- tyramine N-methyltransferase,
2.1.1.28 -- phenylethanolamine N-methyltransferase,
2.1.1.33 -- tRNA (guanine46-N7)-methyltransferase,
2.1.1.34 -- tRNA (guanosine18-2′-O)-methyltransferase,
2.1.1.35 -- tRNA (uracil54-C5)-methyltransferase,
2.1.1.37 -- DNA (cytosine-5-)-methyltransferase,
2.1.1.38 -- O-demethylpuromycin O-methyltransferase,
2.1.1.39 -- inositol 3-methyltransferase,
2.1.1.40 -- inositol 1-methyltransferase,
2.1.1.41 -- sterol 24-C-methyltransferase,
2.1.1.42 -- flavone 3′-O-methyltransferase,
2.1.1.43 -- histone-lysine N-methyltransferase,
2.1.1.44 -- L-histidine Nα-methyltransferase,
2.1.1.45 -- thymidylate synthase,
2.1.1.46 -- isoflavone 4′-O-methyltransferase,
2.1.1.47 -- indolepyruvate C-methyltransferase,
2.1.1.49 -- amine N-methyltransferase,
2.1.1.50 -- loganate O-methyltransferase,
2.1.1.53 -- putrescine N-methyltransferase,
2.1.1.54 -- deoxycytidylate C-methyltransferase,
2.1.1.55 -- tRNA (adenine-N6-)-methyltransferase,
2.1.1.56 -- mRNA (guanine-N7)-methyltransferase,
2.1.1.57 -- methyltransferase cap1,
2.1.1.59 -- [cytochrome c]-lysine N-methyltransferase,
2.1.1.60 -- calmodulin-lysine N-methyltransferase,
2.1.1.61 -- tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase,
2.1.1.62 -- mRNA (2′-O-methyladenosine-N6-)-methyltransferase,
2.1.1.63 -- methylated-DNA—[protein]-cysteine S-methyltransferase,
2.1.1.64 -- 3-demethylubiquinol 3-O-methyltransferase,
2.1.1.65 -- licodione 2′-O-methyltransferase,
2.1.1.67 -- thiopurine S-methyltransferase,
2.1.1.68 -- caffeate O-methyltransferase,
2.1.1.69 -- 5-hydroxyfuranocoumarin 5-O-methyltransferase,
2.1.1.70 -- 8-hydroxyfuranocoumarin 8-O-methyltransferase,
2.1.1.71 -- phosphatidyl-N-methylethanolamine N-methyltransferase,
2.1.1.72 -- site-specific DNA-methyltransferase (adenine-specific),
2.1.1.74 -- methylenetetrahydrofolate—tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing),
2.1.1.75 -- apigenin 4′-O-methyltransferase,
2.1.1.76 -- quercetin 3-O-methyltransferase,
2.1.1.77 -- protein-L-isoaspartate(D-aspartate) O-methyltransferase,
2.1.1.78 -- isoorientin 3′-O-methyltransferase,
2.1.1.79 -- cyclopropane-fatty-acyl-phospholipid synthase,
2.1.1.80 -- protein-glutamate O-methyltransferase,
2.1.1.82 -- 3-methylquercetin 7-O-methyltransferase,
2.1.1.83 -- 3,7-dimethylquercetin 4′-O-methyltransferase,
2.1.1.84 -- methylquercetagetin 6-O-methyltransferase,
2.1.1.85 -- protein-histidine N-methyltransferase,
2.1.1.86 -- tetrahydromethanopterin S-methyltransferase,
2.1.1.87 -- pyridine N-methyltransferase,
2.1.1.88 -- 8-hydroxyquercetin 8-O-methyltransferase,
2.1.1.89 -- tetrahydrocolumbamine 2-O-methyltransferase,
2.1.1.90 -- methanol—corrinoid protein Co-methyltransferase,
2.1.1.91 -- isobutyraldoxime O-methyltransferase,
2.1.1.94 -- tabersonine 16-O-methyltransferase,
2.1.1.95 -- tocopherol O-methyltransferase,
2.1.1.96 -- thioether S-methyltransferase,
2.1.1.97 -- 3-hydroxyanthranilate 4-C-methyltransferase,
2.1.1.98 -- diphthine synthase,
2.1.1.99 -- 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase,
2.1.1.100 -- protein-S-isoprenylcysteine O-methyltransferase,
2.1.1.101 -- macrocin O-methyltransferase,
2.1.1.102 -- demethylmacrocin O-methyltransferase,
2.1.1.103 -- phosphoethanolamine N-methyltransferase,
2.1.1.104 -- caffeoyl-CoA O-methyltransferase,
2.1.1.105 -- N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase,
2.1.1.106 -- tryptophan 2-C-methyltransferase,
2.1.1.107 -- uroporphyrinogen-III C-methyltransferase,
2.1.1.108 -- 6-hydroxymellein O-methyltransferase,
2.1.1.109 -- demethylsterigmatocystin 6-O-methyltransferase,
2.1.1.110 -- sterigmatocystin 8-O-methyltransferase,
2.1.1.111 -- anthranilate N-methyltransferase,
2.1.1.112 -- glucuronoxylan 4-O-methyltransferase,
2.1.1.113 -- site-specific DNA-methyltransferase (cytosine-N4-specific),
2.1.1.114 -- polyprenyldihydroxybenzoate methyltransferase,
2.1.1.115 -- (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase,
2.1.1.116 -- 3′-hydroxy-N-methyl-(S)-coclaurine 4′-O-methyltransferase,
2.1.1.117 -- (S)-scoulerine 9-O-methyltransferase,
2.1.1.118 -- columbamine O-methyltransferase,
2.1.1.119 -- 10-hydroxydihydrosanguinarine 10-O-methyltransferase,
2.1.1.120 -- 12-hydroxydihydrochelirubine 12-O-methyltransferase,
2.1.1.121 -- 6-O-methylnorlaudanosoline 5′-O-methyltransferase,
2.1.1.122 -- (S)-tetrahydroprotoberberine N-methyltransferase,
2.1.1.123 -- [cytochrome-c]-methionine S-methyltransferase,
2.1.1.127 -- [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase,
2.1.1.128 -- (RS)-norcoclaurine 6-O-methyltransferase,
2.1.1.129 -- inositol 4-methyltransferase,
2.1.1.130 -- precorrin-2 C20-methyltransferase,
2.1.1.131 -- precorrin-3B C17-methyltransferase,
2.1.1.132 -- precorrin-6B C5,15-methyltransferase (decarboxylating),
2.1.1.133 -- precorrin-4 C11-methyltransferase,
2.1.1.136 -- chlorophenol O-methyltransferase,
2.1.1.137 -- arsenite methyltransferase,
2.1.1.139 -- 3′-demethylstaurosporine O-methyltransferase,
2.1.1.140 -- (S)-coclaurine-N-methyltransferase,
2.1.1.141 -- jasmonate O-methyltransferase,
2.1.1.142 -- cycloartenol 24-C-methyltransferase,
2.1.1.143 -- 24-methylenesterol C-methyltransferase,
2.1.1.144 -- trans-aconitate 2-methyltransferase,
2.1.1.145 -- trans-aconitate 3-methyltransferase,
2.1.1.146 -- (iso)eugenol O-methyltransferase,
2.1.1.147 -- corydaline synthase,
2.1.1.148 -- thymidylate synthase (FAD),
2.1.1.150 -- isoflavone 7-O-methyltransferase,
2.1.1.151 -- cobalt-factor II C20-methyltransferase,
2.1.1.152 -- precorrin-6A synthase (deacetylating),
2.1.1.153 -- vitexin 2′′-O-rhamnoside 7-O-methyltransferase,
2.1.1.154 -- isoliquiritigenin 2′-O-methyltransferase,
2.1.1.155 -- kaempferol 4′-O-methyltransferase,
2.1.1.156 -- glycine/sarcosine N-methyltransferase,
2.1.1.157 -- sarcosine/dimethylglycine N-methyltransferase,
2.1.1.158 -- 7-methylxanthosine synthase,
2.1.1.159 -- theobromine synthase,
2.1.1.160 -- caffeine synthase,
2.1.1.161 -- dimethylglycine N-methyltransferase,
2.1.1.162 -- glycine/sarcosine/dimethylglycine N-methyltransferase,
2.1.1.163 -- demethylmenaquinone methyltransferase,
2.1.1.164 -- demethylrebeccamycin-D-glucose O-methyltransferase,
2.1.1.165 -- methyl halide transferase,
2.1.1.166 -- 23S rRNA (uridine2552-2′-O)-methyltransferase,
2.1.1.167 -- 27S pre-rRNA (guanosine2922-2′-O)-methyltransferase,
2.1.1.168 -- 21S rRNA (uridine2791-2′-O)-methyltransferase,
2.1.1.169 -- tricetin 3′,4′,5′-O-trimethyltransferase,
2.1.1.170 -- 16S rRNA (guanine527-N7)-methyltransferase,
2.1.1.171 -- 16S rRNA (guanine966-N2)-methyltransferase,
2.1.1.172 -- 16S rRNA (guanine1207-N2)-methyltransferase,
2.1.1.173 -- 23S rRNA (guanine2445-N2)-methyltransferase,
2.1.1.174 -- 23S rRNA (guanine1835-N2)-methyltransferase,
2.1.1.175 -- tricin synthase,
2.1.1.176 -- 16S rRNA (cytosine967-C5)-methyltransferase,
2.1.1.177 -- 23S rRNA (pseudouridine1915-N3)-methyltransferase,
2.1.1.178 -- 16S rRNA (cytosine1407-C5)-methyltransferase,
2.1.1.179 -- 16S rRNA (guanine1405-N7)-methyltransferase,
2.1.1.180 -- 16S rRNA (adenine1408-N1)-methyltransferase,
2.1.1.181 -- 23S rRNA (adenine1618-N6)-methyltransferase,
2.1.1.182 -- 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase,
2.1.1.183 -- 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase,
2.1.1.184 -- 23S rRNA (adenine2085-N6)-dimethyltransferase,
2.1.1.185 -- 23S rRNA (guanosine2251-2′-O)-methyltransferase,
2.1.1.186 -- 23S rRNA (cytidine2498-2′-O)-methyltransferase,
2.1.1.187 -- 23S rRNA (guanine745-N1)-methyltransferase,
2.1.1.188 -- 23S rRNA (guanine748-N1)-methyltransferase,
2.1.1.189 -- 23S rRNA (uracil747-C5)-methyltransferase,
2.1.1.190 -- 23S rRNA (uracil1939-C5)-methyltransferase,
2.1.1.191 -- 23S rRNA (cytosine1962-C5)-methyltransferase,
2.1.1.192 -- 23S rRNA (adenine2503-C2)-methyltransferase,
2.1.1.193 -- 16S rRNA (uracil1498-N3)-methyltransferase,
2.1.1.195 -- cobalt-precorrin-5B (C1)-methyltransferase,
2.1.1.196 -- cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating],
2.1.1.197 -- malonyl-[acyl-carrier protein] O-methyltransferase,
2.1.1.198 -- 16S rRNA (cytidine1402-2′-O)-methyltransferase,
2.1.1.199 -- 16S rRNA (cytosine1402-N4)-methyltransferase,
2.1.1.200 -- tRNA (cytidine32/uridine32-2′-O)-methyltransferase,
2.1.1.201 -- 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase,
2.1.1.202 -- multisite-specific tRNA:(cytosine-C5)-methyltransferase,
2.1.1.203 -- tRNA (cytosine34-C5)-methyltransferase,
2.1.1.204 -- tRNA (cytosine38-C5)-methyltransferase,
2.1.1.205 -- tRNA (cytidine32/guanosine34-2′-O)-methyltransferase,
2.1.1.206 -- tRNA (cytidine56-2′-O)-methyltransferase,
2.1.1.207 -- tRNA (cytidine34-2′-O)-methyltransferase,
2.1.1.208 -- 23S rRNA (uridine2479-2′-O)-methyltransferase,
2.1.1.209 -- 23S rRNA (guanine2535-N1)-methyltransferase,
2.1.1.210 -- demethylspheroidene O-methyltransferase,
2.1.1.211 -- tRNASer (uridine44-2′-O)-methyltransferase,
2.1.1.212 -- 2,7,4′-trihydroxyisoflavanone 4′-O-methyltransferase,
2.1.1.213 -- tRNA (guanine10-N2)-dimethyltransferase,
2.1.1.214 -- tRNA (guanine10-N2)-methyltransferase,
2.1.1.215 -- tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase,
2.1.1.216 -- tRNA (guanine26-N2)-dimethyltransferase,
2.1.1.217 -- tRNA (adenine22-N1)-methyltransferase,
2.1.1.218 -- tRNA (adenine9-N1)-methyltransferase,
2.1.1.219 -- tRNA (adenine57-N1/adenine58-N1)-methyltransferase,
2.1.1.220 -- tRNA (adenine58-N1)-methyltransferase,
2.1.1.221 -- tRNA (guanine9-N1)-methyltransferase,
2.1.1.222 -- 2-polyprenyl-6-hydroxyphenol methylase,
2.1.1.223 -- tRNA1Val (adenine37-N6)-methyltransferase,
2.1.1.224 -- 23S rRNA (adenine2503-C8)-methyltransferase,
2.1.1.225 -- tRNA:m4X modification enzyme,
2.1.1.226 -- 23S rRNA (cytidine1920-2′-O)-methyltransferase,
2.1.1.227 -- 16S rRNA (cytidine1409-2′-O)-methyltransferase,
2.1.1.228 -- tRNA (guanine37-N1)-methyltransferase,
2.1.1.229 -- tRNA (carboxymethyluridine34-5-O)-methyltransferase,
2.1.1.230 -- 23S rRNA (adenosine1067-2′-O)-methyltransferase,
2.1.1.231 -- flavonoid 4′-O-methyltransferase,
2.1.1.232 -- naringenin 7-O-methyltransferase,
2.1.1.233 -- [phosphatase 2A protein]-leucine-carboxy methyltransferase,
2.1.1.234 -- dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase,
2.1.1.235 -- dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase,
2.1.1.236 -- dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase,
2.1.1.237 -- mycinamicin III 3′′-O-methyltransferase,
2.1.1.238 -- mycinamicin VI 2′′-O-methyltransferase,
2.1.1.239 -- L-olivosyl-oleandolide 3-O-methyltransferase,
2.1.1.240 -- trans-resveratrol di-O-methyltransferase,
2.1.1.241 -- 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase,
2.1.1.242 -- 16S rRNA (guanine1516-N2)-methyltransferase,
2.1.1.243 -- 2-ketoarginine methyltransferase,
2.1.1.244 -- protein N-terminal methyltransferase,
2.1.1.245 -- 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase,
2.1.1.246 -- [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase,
2.1.1.247 -- [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase,
2.1.1.248 -- methylamine—corrinoid protein Co-methyltransferase,
2.1.1.249 -- dimethylamine—corrinoid protein Co-methyltransferase,
2.1.1.250 -- trimethylamine—corrinoid protein Co-methyltransferase,
2.1.1.251 -- methylated-thiol—coenzyme M methyltransferase,
2.1.1.252 -- tetramethylammonium—corrinoid protein Co-methyltransferase,
2.1.1.253 -- [methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme M methyltransferase,
2.1.1.254 -- erythromycin 3′′-O-methyltransferase,
2.1.1.255 -- geranyl diphosphate 2-C-methyltransferase,
2.1.1.256 -- tRNA (guanine6-N2)-methyltransferase,
2.1.1.257 -- tRNA (pseudouridine54-N1)-methyltransferase,
2.1.1.258 -- 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase,
2.1.1.259 -- [fructose-bisphosphate aldolase]-lysine N-methyltransferase,
2.1.1.260 -- rRNA small subunit pseudouridine methyltransferase Nep1,
2.1.1.261 -- 4-dimethylallyltryptophan N-methyltransferase,
2.1.1.262 -- squalene methyltransferase,
2.1.1.263 -- botryococcene C-methyltransferase,
2.1.1.264 -- 23S rRNA (guanine2069-N7)-methyltransferase,
2.1.1.265 -- tellurite methyltransferase,
2.1.1.266 -- 23S rRNA (adenine2030-N6)-methyltransferase,
2.1.1.267 -- flavonoid 3′,5′-methyltransferase,
2.1.1.268 -- tRNAThr (cytosine32-N3)-methyltransferase ,
2.1.1.269 -- dimethylsulfoniopropionate demethylase,
2.1.1.270 -- (+)-6a-hydroxymaackiain 3-O-methyltransferase,
2.1.1.271 -- cobalt-precorrin-4 methyltransferase,
2.1.1.272 -- cobalt-factor III methyltransferase,
2.1.1.273 -- benzoate O-methyltransferase,
2.1.1.274 -- salicylate 1-O-methyltransferase,
2.1.1.275 -- gibberellin A9 O-methyltransferase,
2.1.1.276 -- gibberellin A4 carboxyl methyltransferase,
2.1.1.277 -- anthranilate O-methyltransferase,
2.1.1.278 -- indole-3-acetate O-methyltransferase,
2.1.1.279 -- trans-anol O-methyltransferase,
2.1.1.280 -- selenocysteine Se-methyltransferase,
2.1.1.281 -- phenylpyruvate C3-methyltransferase,
2.1.1.282 -- tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase,
2.1.1.283 -- emodin O-methyltransferase,
2.1.1.284 -- 8-demethylnovobiocic acid C8-methyltransferase,
2.1.1.285 -- demethyldecarbamoylnovobiocin O-methyltransferase,
2.1.1.286 -- 25S rRNA (adenine2142-N1)-methyltransferase,
2.1.1.287 -- 25S rRNA (adenine645-N1)-methyltransferase,
2.1.1.288 -- aklanonic acid methyltransferase,
2.1.1.289 -- cobalt-precorrin-7 (C5)-methyltransferase,
2.1.1.290 -- tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase,
2.1.1.291 -- (R,S)-reticuline 7-O-methyltransferase,
2.1.1.292 -- carminomycin 4-O-methyltransferase,
2.1.1.293 -- 6-hydroxytryprostatin B O-methyltransferase,
2.1.1.294 -- 3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase,
2.1.1.295 -- 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase,
2.1.1.296 -- methyltransferase cap2,
2.1.1.297 -- peptide chain release factor N5-glutamine methyltransferase,
2.1.1.298 -- ribosomal protein L3 N5-glutamine methyltransferase,
2.1.1.299 -- protein N-terminal monomethyltransferase,
2.1.1.300 -- pavine N-methyltransferase,
2.1.1.301 -- cypemycin N-terminal methyltransferase ,
2.1.1.302 -- 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase,
2.1.1.303 -- 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase,
2.1.1.304 -- L-tyrosine C3-methyltransferase,
2.1.1.305 -- 8-demethyl-8-α-L-rhamnosyltetracenomycin-C 2′-O-methyltransferase,
2.1.1.306 -- 8-demethyl-8-(2-methoxy-α-L-rhamnosyl)tetracenomycin-C 3′-O-methyltransferase,
2.1.1.307 -- 8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)tetracenomycin-C 4′-O-methyltransferase,
2.1.1.308 -- 2-hydroxyethylphosphonate methyltransferase,
2.1.1.309 -- 18S rRNA (guanine1575-N7)-methyltransferase,
2.1.1.310 -- 25S rRNA (cytosine2870-C5)-methyltransferase,
2.1.1.311 -- 25S rRNA (cytosine2278-C5)-methyltransferase,
2.1.1.312 -- 25S rRNA (uracil2843-N3)-methyltransferase,
2.1.1.313 -- 25S rRNA (uracil2634-N3)-methyltransferase,
2.1.1.314 -- diphthine methyl ester synthase,
2.1.1.315 -- 27-O-demethylrifamycin SV methyltransferase,
2.1.1.316 -- mitomycin-6-O-methyltransferase,
2.1.1.317 -- sphingolipid C9-methyltransferase,
2.1.1.318 -- [trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase,
2.1.1.fg -- juvenile hormone acid methyltransferase,
2.1.1.fm -- type I protein arginine methyltransferase,
2.1.1.fn -- type II protein arginine methyltransferase,
2.1.1.fo -- type III protein arginine methyltransferase,
2.1.1.fp -- type IV protein arginine methyltransferase,
2.1.1.fq -- 2-phytyl-1,4-naphthoquinone methyltransferase,
2.1.1.fr -- phenazine-1-carboxylate N-methyltransferase,
2.1.1.fs -- N-acetyl-demethylphophinothricin P-methyltransferase,
2.1.1.M5,
2.1.1.M6,
2.1.1.M7,
2.1.1.M8,
2.1.1.M9 -- 5-hydroxy-benzimidazole O-methyltransferase,
2.1.1.M10 -- 5-methoxy-benzimidazole C-methyltransferase,
2.1.1.M12 -- phthiotriol methyltransferase

Unofficial Reactions:
S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-α-D-glucose → S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose + H+,
S-adenosyl-L-methionine + cirsiliol → S-adenosyl-L-homocysteine + cirsilineol + H+,
cephaeline + S-adenosyl-L-methionine → emetine + S-adenosyl-L-homocysteine + H+,
2 S-adenosyl-L-methionine + S-demethyl-thiocoraline dithiol → thiocoraline dithiol + 2 S-adenosyl-L-homocysteine + 2 H+,
3,7,3'-trimethylquercetagetin + S-adenosyl-L-methionine → 3,6,7,3'-tetramethylquercetagetin + S-adenosyl-L-homocysteine + H+,
3,6,7-trimethylquercetagetin + S-adenosyl-L-methionine → 3,6,7,4'-tetramethylquercetagetin + S-adenosyl-L-homocysteine + H+,
ladanein + S-adenosyl-L-methionine → salvigenin + S-adenosyl-L-homocysteine + H+,
dithiolgliotoxin + S-adenosyl-L-methionine → mono(methylthio)gliotoxin + S-adenosyl-L-homocysteine + H+,
N-monomethylethanolamine + S-adenosyl-L-methionine → N-dimethylethanolamine + S-adenosyl-L-homocysteine + H+,
3,7,3',5'-tetramethylmyricetin + S-adenosyl-L-methionine → 3,7,3',4',5'-pentamethylmyricetin + S-adenosyl-L-homocysteine + H+,
(S)-norreticuline + S-adenosyl-L-methionine → (S)-norlaudanine + S-adenosyl-L-homocysteine + H+,
5-O-methylthujaplicatin + S-adenosyl-L-methionine → 4,5-O,O-dimethylthujaplicatin + S-adenosyl-L-homocysteine + H+,
hydroxyspirilloxanthin + S-adenosyl-L-methionine → spirilloxanthin + S-adenosyl-L-homocysteine + H+,
furaneol (enol form) + S-adenosyl-L-methionine → methoxyfuraneol (enol form) + S-adenosyl-L-homocysteine + H+,
4-demethylwyosine37 in tRNAPhe + S-adenosyl-L-methionine → wyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+,
scutellarein 7-methyl ether + S-adenosyl-L-methionine → cirsimaritin + S-adenosyl-L-homocysteine + H+,
desmethyl-dehydro-dechlorogriseofulvin + S-adenosyl-L-methionine → dechloro-dehydrogriseofulvin + S-adenosyl-L-homocysteine + H+,
glandicoline B + S-adenosyl-L-methionine → meleagrin + S-adenosyl-L-homocysteine + H+,
4α,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + a methylated methyl donor = cycloartenol + a demethylated methyl donor,
3,7-dimethylquercetagetin + S-adenosyl-L-methionine → 3,7,4'-trimethylquercetagetin + S-adenosyl-L-homocysteine + H+,
eriodictyol + S-adenosyl-L-methionine → homoeriodictyol + S-adenosyl-L-homocysteine + H+,
N-demethyllincomycin + S-adenosyl-L-methionine → lincomycin A + S-adenosyl-L-homocysteine + H+,
desmethylxanthohumol + S-adenosyl-L-methionine → xanthohumol + S-adenosyl-L-homocysteine + H+,
7-O-methylmyricetin + S-adenosyl-L-methionine → 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+,
7-deoxyloganate + S-adenosyl-L-methionine → 7-deoxyloganin + S-adenosyl-L-homocysteine,
isoscopoletin + S-adenosyl-L-methionine → scoparone + S-adenosyl-L-homocysteine + H+,
2 S-adenosyl-L-methionine + an adenine37 in tRNA + 2 a reduced [2Fe-2S] ferredoxin → S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA + 2 an oxidized [2Fe-2S] ferredoxin,
N6-L-threonylcarbamoyladenine37 in tRNA + S-adenosyl-L-methionine → N6-methyl-threonylcarbamoyladenosine 37 in tRNA + S-adenosyl-L-homocysteine + H+,
tetracenomycin D3 + S-adenosyl-L-methionine → tetracenomycin B3 + S-adenosyl-L-homocysteine,
5-pentadecatrienyl resorcinol + S-adenosyl-L-methionine → 5-pentadecatrienyl resorcinol-3-methyl ether + S-adenosyl-L-homocysteine + H+,
lactenocin + S-adenosyl-L-methionine → desmycosin + S-adenosyl-L-homocysteine + H+,
dTDP-4-dehydro-β-L-rhamnose + S-adenosyl-L-methionine → dTDP-4-dehydro-5-methyl-β-L-rhamnose + S-adenosyl-L-homocysteine + H+,
3,5-dihydroxybiphenyl + S-adenosyl-L-methionine → 3-hydroxy-5-methoxybiphenyl + S-adenosyl-L-homocysteine + H+,
laricitrin + S-adenosyl-L-methionine → 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+,
isorhamnetin + S-adenosyl-L-methionine → 3',4'-dimethylquercetin + S-adenosyl-L-homocysteine,
a [glycerolipid]-vaccenate + S-adenosyl-L-methionine → a [glycerolipid]-(E)-11-methyl-12-octadec-12-enoate + S-adenosyl-L-homocysteine + H+,
24-methylenecycloartanol + a demethylated methyl donor = cycloeucalenol + a methylated methyl donor,
coniferyl alcohol + S-adenosyl-L-methionine → coniferyl alcohol 9-methyl ester + S-adenosyl-L-homocysteine + H+,
patuletin + S-adenosyl-L-methionine → quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+,
2-(2,4-dihydroxy-6-methylbenzoyl)benzene-1,3,5-triol + S-adenosyl-L-methionine → griseophenone D + S-adenosyl-L-homocysteine + H+,
N-methyl-3-aminomethylindole + S-adenosyl-L-methionine → gramine + S-adenosyl-L-homocysteine + H+,
gentamicin X2 + S-adenosyl-L-methionine → G-418 + S-adenosyl-L-homocysteine + H+,
a CpG site + S-adenosyl-L-methionine → a 5-methyl-CpG site + S-adenosyl-L-homocysteine + H+,
dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose + S-adenosyl-L-methionine → dTDP-2,3,6-trideoxy-3-C-methyl-3-amino-4-dehydro-α-D-glucose + S-adenosyl-L-homocysteine + H+,
glutathione + a methylated methyl donor → S-methylglutathione + a demethylated methyl donor,
quercetagetin 7-O-glucoside + S-adenosyl-L-methionine → patulitrin + S-adenosyl-L-homocysteine + H+,
syringetin + S-adenosyl-L-methionine → 3',4',5'-trimethylmyricetin + S-adenosyl-L-homocysteine,
rhamnetin + S-adenosyl-L-methionine → 7,4'-dimethylquercetin + S-adenosyl-L-homocysteine + H+,
fusarubinaldehyde + S-adenosyl-L-methionine → 8-O-methylfusarubinaldehyde + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + 3'-O-methyltricetin → S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin + H+,
demethylsulochrin + S-adenosyl-L-methionine → sulochrin + S-adenosyl-L-homocysteine,
3,5-dimethoxyphenol + S-adenosyl-L-methionine → 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine + H+,
tetracenomycin E + S-adenosyl-L-methionine → tetracenomycin A2 + S-adenosyl-L-homocysteine,
S-adenosyl-L-methionine + myo-inositol → S-adenosyl-L-homocysteine + sequoyitol + H+,
bixin + S-adenosyl-L-methionine → bixin dimethyl ester + S-adenosyl-L-homocysteine,
gibberellin A34 + S-adenosyl-L-methionine → methyl gibberellin A34 + S-adenosyl-L-homocysteine,
6-O-methyl-N-deacetylisoipecoside aglycon + S-adenosyl-L-methionine → 6,7-O,O-dimethyl-N-deacetylisoipecoside aglycon + S-adenosyl-L-homocysteine + H+,
2'-hydroxy 3,6,7,4'-tetramethylquercetagetin 3'-O-β-D-glucoside + S-adenosyl-L-methionine → 3,6,7,2',4'-pentamethylquercetagetin 3'-O-β-D-glucoside + S-adenosyl-L-homocysteine + H+,
syringetin + S-adenosyl-L-methionine → 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine,
kaempferide + S-adenosyl-L-methionine → 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine,
1-hydroxyneurosporene + S-adenosyl-L-methionine → methoxyneurosporene + S-adenosyl-L-homocysteine + H+,
norbikaverin + S-adenosyl-L-methionine → bikaverin + S-adenosyl-L-homocysteine,
tetrahymanol + methylcob(III)alamin + S-adenosyl-L-methionine → 2-methyltetrahymanol + 5'-deoxyadenosine + L-methionine + cob(III)alamin,
12-demethyl-elloramycin + S-adenosyl-L-methionine → elloramycin + S-adenosyl-L-homocysteine + H+,
trihydroxyferuloyl spermidine + S-adenosyl-L-methionine → dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose → S-adenosyl-L-homocysteine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-α-D-glucose + H+,
S-stylopine + S-adenosyl-L-methionine → (S)-cis-N-methylstylopine + S-adenosyl-L-homocysteine,
S-methyl-L-methionine + L-selenocysteine = Se-methyl-L-selenocysteine + L-methionine + H+,
norajmaline + S-adenosyl-L-methionine → ajmaline + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone → S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone + H+,
5-hydroxy-desmethylanthrotainin + S-adenosyl-L-methionine → 5-hydroxyanthrotainin + S-adenosyl-L-homocysteine + H+,
3'-O-demethyl-4'-N-demethyl-staurosporine + S-adenosyl-L-methionine → 3'-O-demethyl-staurosporine + S-adenosyl-L-homocysteine + H+,
7'-O-demethylcephaeline + S-adenosyl-L-methionine → cephaeline + S-adenosyl-L-homocysteine + H+,
3,7,4'-trimethylquercetin + S-adenosyl-L-methionine → 3,7,3',4'-tetramethylquercetin + S-adenosyl-L-homocysteine + H+,
3,7-dimethylquercetagetin + S-adenosyl-L-methionine → 3,7,3'-trimethylquercetagetin + S-adenosyl-L-homocysteine + H+,
trichosetin + S-adenosyl-L-methionine → equisetin + S-adenosyl-L-homocysteine + H+,
ethanolamine + S-adenosyl-L-methionine → N-monomethylethanolamine + S-adenosyl-L-homocysteine + H+,
vanillate + a tetrahydrofolate → protocatechuate + an N5-methyl-tetrahydrofolate,
S-adenosyl-L-methionine + 4-hydroxy-3-indolylmethyl-glucosinolate → 4-methoxy-3-indolylmethyl-glucosinolate + S-adenosyl-L-homocysteine + H+,
3,7,3'-trimethylmyricetin + S-adenosyl-L-methionine → 3,7,3',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+,
(S)-laudanine + S-adenosyl-L-methionine → laudanosine + S-adenosyl-L-homocysteine + H+,
(-)-thujaplicatin + S-adenosyl-L-methionine → 5-O-methylthujaplicatin + S-adenosyl-L-homocysteine + H+,
5-hydroxymethylcytosine + S-adenosyl-L-methionine → bacimethrin + S-adenosyl-L-homocysteine + H+,
nor-rubrofusarin + S-adenosyl-L-methionine → rubrofusarin + S-adenosyl-L-homocysteine + H+,
L-leucyl-demethylarginomycin + S-adenosyl-L-methionine → L-leucyl-arginomycin + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + a demethylmenaquinone → S-adenosyl-L-homocysteine + a menaquinone,
S-adenosyl-L-methionine + apigenin → S-adenosyl-L-homocysteine + genkwanin,
2'-hydroxy 3,7,4'-trimethylquercetin + S-adenosyl-L-methionine → 2'-hydroxy 3,7,3',4'-tetramethylquercetin + S-adenosyl-L-homocysteine + H+,
3-hexaprenyl-4-amino-5-hydroxybenzoate + S-adenosyl-L-methionine → 3-hexaprenyl-4-amino-5-methoxybenzoate + S-adenosyl-L-homocysteine + H+,
myricetin + S-adenosyl-L-methionine → 7-O-methylmyricetin + S-adenosyl-L-homocysteine,
esculetin + S-adenosyl-L-methionine → isoscopoletin + S-adenosyl-L-homocysteine + H+,
(-)-vestitol + S-adenosyl-L-methionine → (-)-sativan + S-adenosyl-L-homocysteine + H+,
mercaptohistidine + S-adenosyl-L-methionine → ovothiol + S-adenosyl-L-homocysteine + H+,
pluviatolide + S-adenosyl-L-methionine → bursehernin + S-adenosyl-L-homocysteine + H+,
L-leucyl-demethyl-blasticidin S + S-adenosyl-L-methionine → L-leucyl-blasticidin S + S-adenosyl-L-homocysteine + H+,
tetracenomycin B3 + S-adenosyl-L-methionine → tetracenomycin B2 + S-adenosyl-L-homocysteine,
24-ethylidenelophenol + a demethylated methyl donor = avenasterol + a methylated methyl donor,
cirsimaritin + S-adenosyl-L-methionine → salvigenin + S-adenosyl-L-homocysteine + H+,
demethyllactenocin + S-adenosyl-L-methionine → lactenocin + S-adenosyl-L-homocysteine + H+,
(S)-isoandrocymbine + S-adenosyl-L-methionine → O-methylandrocymbine + S-adenosyl-L-homocysteine + H+,
2-hexaprenyl-6-methoxyaminophenol + S-adenosyl-L-methionine → 2-hexaprenyl-3-methyl-6-methoxyaminophenol + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + an N terminal N,N-dimethyl-(A/S)PK-[protein] → S-adenosyl-L-homocysteine + an N terminal N,N,N-trimethyl-(A/S)PK-[protein],
laricitrin + S-adenosyl-L-methionine → 3,3'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+,
3-O-methylquercetin + S-adenosyl-L-methionine → 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine,
1-(3,4-dihydroxyphenyl)-5-hydroxy-3-decanone + S-adenosyl-L-methionine → 6-gingerol + S-adenosyl-L-homocysteine + H+,
(-)-matairesinol + S-adenosyl-L-methionine → isoarctigenin + S-adenosyl-L-homocysteine + H+,
3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine → 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine + H+,
3-aminomethylindole + S-adenosyl-L-methionine → N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine + H+,
gentamicin A + S-adenosyl-L-methionine → gentamicin X2 + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + β-D-glucuronate-(1,3)-β-D-glucuronate-(1,3)-β-D-glucuronate-(1,3)-hexose-(C55 ω-saturated dolichyl phosphate) → S-adenosyl-L-homocysteine + O-methyl-β-D-glucuronate-(1,3)-β-D-glucuronate-(1,3)-β-D-glucuronate-(1,3)-hexose-(C55 ω-saturated dolichyl phosphate),
β-peltatin + S-adenosyl-L-methionine → β-peltatin-A methyl ether + S-adenosyl-L-homocysteine + H+,
noraucuparin + S-adenosyl-L-methionine → aucuparin + S-adenosyl-L-homocysteine + H+,
3,6,7,4'-tetramethylquercetagetin + S-adenosyl-L-methionine → 3,6,7,3',4'-pentamethylquercetagetin + S-adenosyl-L-homocysteine + H+,
quercetagetin + S-adenosyl-L-methionine → patuletin + S-adenosyl-L-homocysteine + H+,
methyl-CoM + tetrahydrosarcinapterin ↔ 5-methyl-tetrahydrosarcinapterin + coenzyme M,
a homogalacturonan + S-adenosyl-L-methionine → methylesterified 1,4-α-D-galactosyluronate + S-adenosyl-L-homocysteine + H+,
3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine → 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+,
rhamnetin + S-adenosyl-L-methionine → 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine + H+,
N,N-dimethyl-β-alanine + S-adenosyl-L-methionine → β-alanine betaine + S-adenosyl-L-homocysteine + H+,
6-O-demethylfusarubinaldehyde + S-adenosyl-L-methionine → fusarubinaldehyde + S-adenosyl-L-homocysteine + H+,
tricetin + S-adenosyl-L-methionine → 3'-O-methyltricetin + S-adenosyl-L-homocysteine + H+,
3,5-dihydroxyanisole + S-adenosyl-L-methionine → 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine + H+,
tetracenomycin B3 + S-adenosyl-L-methionine → tetracenomycin E + S-adenosyl-L-homocysteine + H+,
thiocyanate + S-adenosyl-L-methionine → methyl thiocyanate + S-adenosyl-L-homocysteine,
1-O-caffeoyl-β-D-glucose + S-adenosyl-L-methionine → 1-O-feruloyl-β-D-glucose + S-adenosyl-L-homocysteine + H+,
syringate + a tetrahydrofolate → 3-O-methylgallate + an N5-methyl-tetrahydrofolate,
norbixin + S-adenosyl-L-methionine → bixin + S-adenosyl-L-homocysteine,
3-(methylthio)propanoate + a tetrahydrofolate = 3-mercaptopropanoate + an N5-methyl-tetrahydrofolate,
4α-methyl-5α-cholesta-7,24-dien-3β-ol + a demethylated methyl donor = 5α-cholesta-7,24-dien-3β-ol + a methylated methyl donor,
(S)-corytuberine + S-adenosyl-L-methionine → magnoflorine + S-adenosyl-L-homocysteine + H+,
carboxy-fusarin C + S-adenosyl-L-methionine → fusarin C + S-adenosyl-L-homocysteine,
4-demethylpremithracinone + S-adenosyl-L-methionine → premithracinone + S-adenosyl-L-homocysteine + H+,
patuletin + S-adenosyl-L-methionine → eupatolitin + S-adenosyl-L-homocysteine + H+,
syringetin + S-adenosyl-L-methionine → 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine,
S-adenosyl-L-methionine + daphnetin → S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxycoumarin + H+,
kaempferide + S-adenosyl-L-methionine → 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine,
6-hydroxy-norbikaverin + S-adenosyl-L-methionine → norbikaverin + S-adenosyl-L-homocysteine,
resorcinol + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + 3-methoxyphenol + H+,
gentamicin C2 + S-adenosyl-L-methionine → gentamicin C1 + S-adenosyl-L-homocysteine + H+,
genkwanin + S-adenosyl-L-methionine → apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine + H+,
dTDP-β-L-4-epi-vancosamine + S-adenosyl-L-methionine → dTDP-β-L-evernosamine + S-adenosyl-L-homocysteine + H+,
quercetin + S-adenosyl-L-methionine → rhamnetin + S-adenosyl-L-homocysteine,
3,7-dimethylmyricetin + S-adenosyl-L-methionine → 3,7,3'-trimethylmyricetin + S-adenosyl-L-homocysteine + H+,
isowyosine37 in tRNAPhe + S-adenosyl-L-methionine → 7-methylwyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+,
calycosin + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + 7-hydroxy-4'5'-dimethoxyisoflavone + H+,
1'-hydroxy-1',2'-dihydro-β,ψ-caroten-4'-one + S-adenosyl-L-methionine → thiothece-474 + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + 8-hydroxy-7-methoxy-flavone → S-adenosyl-L-homocysteine + 7,8-dimethoxy-flavone + H+,
2'-hydroxy 3,6,7,4'-tetramethylquercetagetin + S-adenosyl-L-methionine → 3,6,7,2',4'-pentamethylquercetagetin + S-adenosyl-L-homocysteine + H+,
mono(methylthio)gliotoxin + S-adenosyl-L-methionine → bis(methylthio)gliotoxin + S-adenosyl-L-homocysteine + H+,
N-dimethylethanolamine + S-adenosyl-L-methionine → choline + S-adenosyl-L-homocysteine + H+,
7-O-methylmyricetin + S-adenosyl-L-methionine → 3,7-dimethylmyricetin + S-adenosyl-L-homocysteine + H+,
esculetin + S-adenosyl-L-methionine → scopoletin + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + L-homocysteine → L-methionine + S-adenosyl-L-homocysteine + H+,
(S)-norlaudanine + S-adenosyl-L-methionine → (S)-tetrahydropapaverine + S-adenosyl-L-homocysteine + H+,
wyosine37 in tRNAPhe + S-adenosyl-L-methionine → 7-methylwyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+,
scutellarein 7-methyl ether + S-adenosyl-L-methionine → ladanein + S-adenosyl-L-homocysteine + H+,
pilosin + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + nevadensin + H+,
DIBOA-β-D-glucoside + S-adenosyl-L-methionine → 4-O-methyl-DIBOA-glucoside + S-adenosyl-L-homocysteine + H+,
3,7,4'-trimethylquercetagetin + S-adenosyl-L-methionine → 3,6,7,4'-tetramethylquercetagetin + S-adenosyl-L-homocysteine + H+,
eriodictyol + S-adenosyl-L-methionine → hesperetin + S-adenosyl-L-homocysteine + H+,
7-deoxyloganetate + S-adenosyl-L-methionine → 7-deoxyloganetin + S-adenosyl-L-homocysteine,
myricetin + S-adenosyl-L-methionine → 3-O-methylmyricetin + S-adenosyl-L-homocysteine,
isorhamnetin + S-adenosyl-L-methionine → 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine,
S-adenosyl-L-methionine + dTDP-4-dehydro-2,6-dideoxy-α-D-glucose → S-adenosyl-L-homocysteine + dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-D-glucose + H+,
(-)-matairesinol + S-adenosyl-L-methionine → arctigenin + S-adenosyl-L-homocysteine + H+,
DIMBOA-β-D-glucoside + S-adenosyl-L-methionine → HMDBOA-glucoside + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + a demethylated methyl donor → S-adenosyl-L-homocysteine + a methylated methyl donor + H+,
S-adenosyl-L-methionine + 8-hydroxy-salvigenin → S-adenosyl-L-homocysteine + gardenin B + H+,
gibberellin A20 + S-adenosyl-L-methionine → methyl gibberellin A20 + S-adenosyl-L-homocysteine,
dihydrosorgoleone + a methylated methyl donor → methoxydihydrosorgoleone + a demethylated methyl donor,
N1-hydroxy-roquefortine C + S-adenosyl-L-methionine → roquefortine F + S-adenosyl-L-homocysteine + H+,
9-N-hydroxy-L-tryptophan + S-adenosyl-L-methionine → 9-N-methoxy-tryptophan + S-adenosyl-L-homocysteine + H+,
3,7,4'-trimethylquercetin 2'-O-β-D-glucoside + S-adenosyl-L-methionine → 3,7,3',4'-tetramethylquercetin 2'-O-β-D-glucoside + S-adenosyl-L-homocysteine + H+,
gentamicin C1a + S-adenosyl-L-methionine → gentamicin C2b + S-adenosyl-L-homocysteine + H+,
3',4'-dimethylmyricetin + S-adenosyl-L-methionine → 3',4',5'-trimethylmyricetin + S-adenosyl-L-homocysteine,
rhamnetin + S-adenosyl-L-methionine → 3,7-dimethylquercetin + S-adenosyl-L-homocysteine + H+,
N-methyl-β-alanine + S-adenosyl-L-methionine → N,N-dimethyl-β-alanine + S-adenosyl-L-homocysteine + H+,
phloroglucinol + S-adenosyl-L-methionine → 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine + H+,
3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-methionine → gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine + H+,
griseophenone D + S-adenosyl-L-methionine → griseophenone C + S-adenosyl-L-homocysteine + H+,
deacetylisoipecoside + S-adenosyl-L-methionine → 6-O-methyl-N-deacetylisoipecoside + S-adenosyl-L-homocysteine + H+,
rRNA + S-adenosyl-L-methionine → rRNA containing N6,N6-dimethyladenine + S-adenosyl-L-homocysteine,
2'-hydroxy 3,6,7,4'-tetramethylquercetagetin + S-adenosyl-L-methionine → 2'-hydroxy 3,6,7,3',4'-pentamethylquercetagetin + S-adenosyl-L-homocysteine + H+,
3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine → 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+,
kaempferol + S-adenosyl-L-methionine → 3-O-methylkaempferol + S-adenosyl-L-homocysteine,
protocatechualdehyde + S-adenosyl-L-methionine → vanillin + S-adenosyl-L-homocysteine + H+,
4-hydroxy-2,2'-bipyrrole-5-carbaldehyde + S-adenosyl-L-methionine → 4-methoxy-2,2'-bipyrrole-5-carbaldehyde + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + dTDP-4-dehydro-2,6-dideoxy-α-D-allose → S-adenosyl-L-homocysteine + dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-L-allose + H+,
bacteriohopanetetrol + methylcob(III)alamin + S-adenosyl-L-methionine → 2-methylbacteriohopanetetrol + 5'-deoxyadenosine + L-methionine + cob(III)alamin,
coniine + S-adenosyl-L-methionine → methylconiine + S-adenosyl-L-homocysteine + H+,
desoxyhemigossypol + S-adenosyl-L-methionine → desoxyhemigossypol-6-methyl ether + S-adenosyl-L-homocysteine + H+,
tricaffeoyl spermidine + 3 S-adenosyl-L-methionine → triferuloyl spermidine + 3 S-adenosyl-L-homocysteine + 3 H+,
desmethyl-dehydro-griseofulvin + S-adenosyl-L-methionine → dehydrogriseofulvin + S-adenosyl-L-homocysteine + H+,
3-O-methylgallate + a tetrahydrofolate → gallate + an N5-methyl-tetrahydrofolate,
17-O-acetylnorajmaline + S-adenosyl-L-methionine → 17-O-acetylajmaline + S-adenosyl-L-homocysteine + H+,
fusicocca-1,10(14)-diene-3,8β,16-triol + S-adenosyl-L-methionine → fusicocca-1,10(14)-diene-16-(hydroxymethyl)-3,8β-diol + S-adenosyl-L-homocysteine + H+,
papaveroxine intermediate + S-adenosyl-L-methionine → papaveroxine + S-adenosyl-L-homocysteine + H+,
S-adenosyl-L-methionine + triostin A → S-adenosyl-L-homocysteine + echinomycin + H+,
scutellarein 7-methyl ether + 2 S-adenosyl-L-methionine → salvigenin + 2 S-adenosyl-L-homocysteine + 2 H+,
9-demethylpremithramycin A3 + S-adenosyl-L-methionine → premithramycin A3 + S-adenosyl-L-homocysteine + H+,
3-O-methylmyricetin + S-adenosyl-L-methionine → 3,7-dimethylmyricetin + S-adenosyl-L-homocysteine + H+,
2-(all-trans-nonaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine → 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+,
hopan-22-ol + methylcob(III)alamin + S-adenosyl-L-methionine → 2-methyldiplopterol + 5'-deoxyadenosine + L-methionine + cob(III)alamin,
3,4-didehydrorhodopin + S-adenosyl-L-methionine → anhydrorhodovibrin + S-adenosyl-L-homocysteine + H+,
24-methylenelophenol + a demethylated methyl donor = episterol + a methylated methyl donor,
4-demethylwyosine37 in tRNAPhe + S-adenosyl-L-methionine → isowyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+,
tetrahydrosarcinapterin + acetyl-CoA + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O ↔ 5-methyl-tetrahydrosarcinapterin + CO2 + 2 a reduced ferredoxin [iron-sulfur] cluster + coenzyme A + 2 H+,
2 S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose → 2 S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose + 2 H+,
a cis-delta21-39-hydroxy-40-methyl-C59:1-[acp] + S-adenosyl-L-methionine → a trans-delta20-39-hydroxy-40-methyl-C60:1-[acp] + S-adenosyl-L-homocysteine + H+,
N-desmethyl-gliotoxin + S-adenosyl-L-methionine → gliotoxin + S-adenosyl-L-homocysteine + H+,
a cis-delta19-37-hydroxy-38-methyl-C57:1-[acp] + S-adenosyl-L-methionine → a trans-delta18-37-hydroxy-20,38-dimethyl-C58:1-[acp] + S-adenosyl-L-homocysteine + H+,
a cis-delta19-37-hydroxy-38-methyl-C57:1-[acp] + S-adenosyl-L-methionine → a cis-delta19-37-methoxy-38-methyl-C57:1-[acp] + S-adenosyl-L-homocysteine + H+,
a cis,cis-delta21,39-C58:2-[acp] + S-adenosyl-L-methionine + H2O → a cis-delta21-39-hydroxy-40-methyl-C59:1-[acp] + S-adenosyl-L-homocysteine + H+,
a cis,cis-delta19,31-C50:2-[acp] + 2 S-adenosyl-L-methionine → a C52-α-meroacyl-[acp] + 2 S-adenosyl-L-homocysteine + 2 H+,
a trans-delta18-37-methoxy-20,38-dimethyl-C58:1-[acp] + S-adenosyl-L-methionine → a trans-methoxy-C60-meroacyl-[acp] + S-adenosyl-L-homocysteine + H+,
a cis,cis-delta19-37-C56:2-[acp] + S-adenosyl-L-methionine + H2O → a cis-delta19-37-hydroxy-38-methyl-C57:1-[acp] + S-adenosyl-L-homocysteine + H+,
a trans-delta18-37-hydroxy-20,38-dimethyl-C58:1-[acp] + S-adenosyl-L-methionine → a trans-delta18-37-methoxy-20,38-dimethyl-C58:1-[acp] + S-adenosyl-L-homocysteine + H+

Enzymes and Genes:
cyclopropane mycolic acid synthase 2: cmaA2 ( Mycobacterium tuberculosis H37Rv )
cyclopropane synthase: pcaA ( Mycobacterium tuberculosis H37Rv )
methoxy mycolic acid synthase 2: mmaA2 ( Mycobacterium tuberculosis H37Rv )
methoxymycolic acid synthase 4: mmaA4 ( Mycobacterium tuberculosis H37Rv )
methoxy mycolic acid synthase 3: mmaA3 ( Mycobacterium tuberculosis H37Rv )
N-desmethyl-gliotoxin N-methyltransferase: gliN ( Aspergillus fumigatus )
methoxy mycolic acid synthase 1: mmaA1 ( Mycobacterium tuberculosis H37Rv )
acetyl-CoA decarbonylase/synthase complex: cdhB1, cdhA1, cdhE1, cdhD1, cdhC1 ( Methanosarcina thermophila )
tRNA 4-demethylwyosine37-methyltransferase [multifunctional]: trm5a ( Pyrococcus abyssi )
C4-demethylase ( Arabidopsis thaliana col )
premithramycin A3 methyltransferase: mtmMII ( Streptomyces argillaceus )
echinomycin synthase: ecm18 ( Streptomyces lasaliensis )
papaveroxine intermediate 4'-O-methyltransferase: MT2 ( Papaver somniferum )
fusicocca-1,10(14)-diene-3,8β,16-triol O-methyltransferase: bsc6 ( Alternaria brassicicola ATCC 96836 )
desoxyhemigossypol-6-O-methyltransferase: dHG-6-OMT ( Gossypium barbadense )
coniine methyltransferase ( Conium maculatum )
dTDP-4-dehydro-2,6-dideoxy-α-D-allose 3-C-methyltransferase: eryBIII ( Saccharopolyspora erythraea NRRL 2338 )
4-hydroxy-2,2'-bipyrrole-5-carbaldehyde O-methyltransferase: pigF ( Serratia marcescens )
3,4-dihydroxybenzaldehyde-O-methyltransferase: OMT ( Vanilla planifolia )
griseophenone D 9-O-methyltransferase: GsfC ( Penicillium aethiopicum )
phloroglucinol O-methyltransferase: POMT ( Rosa chinensis )
N-hydroxy-L-tryptophan O-methyltransferase: APF6 ( Fusarium fujikuroi )
N-hydroxytryptophan O-methyltransferase: APS6 ( Fusarium incarnatum )
gibberellin carboxyl methyltransferase: GAMT1 ( Arabidopsis thaliana col )
matairesinol 4'-O-methyltransferase: MROMT ( Anthriscus sylvestris )
matairesinol 4'-O-methyltransferase: ctmromt ( Carthamus tinctorius )
D-olivose 4-ketoreductase: mtmC ( Streptomyces argillaceus )
DIBOA/DIMBOA-glucoside 4-O-methyltransferase ( Triticum aestivum )
homocysteine S-methyltransferase: AT3g25900 ( Arabidopsis thaliana col )
homocysteine S-methyltransferase: AT3g63250 ( Arabidopsis thaliana col )
esculetin 6-O-methyltransferase (meta-methylation) ( Nicotiana tabacum )
1'-hydroxy-1',2'-dihydro-β,ψ-caroten-4'-one O-methyltransferase: crtF ( Candidatus Thiodictyon syntrophicum Cad16 )
tRNA isowyosine37 7-methyltransferase 2: taw3-2 ( Pyrococcus abyssi )
tRNA isowyosine37 7-methyltransferase 1: taw3-1 ( Pyrococcus abyssi )
daphnetin 8-O-methyltransferase: ScOMT1 ( Secale cereale )
flavonol 7-O-methyltransferase ( Rudbeckia hirta )
demethylpremithracinone o-methyltransferase: mtmMI ( Streptomyces argillaceus )
carboxy-fusarin C O-methyltransferase: Fus9 ( Fusarium fujikuroi )
coclaurine N-methyltransferase: AB061863 ( Coptis japonica )
syringate O-demethylase: desA ( Sphingomonas sp. SYK6 )
thiocyanate methyltransferase: TMT2 ( Brassica oleracea )
thiocyanate methyltransferase: TMT1 ( Brassica oleracea )
tetracenomycin B3 8-O-methyl transferase: tcmO ( Streptomyces glaucescens )
3,5-dihydroxyanisole O-methyltransferase [multifunctional]: oomt3 ( Rosa hybrid cultivar )
3,5-dihydroxyanisole O-methyltransferase [multifunctional]: oomt1 ( Rosa chinensis )
β-alanine N-methyltransferase: BANMT1 ( Limonium latifolium )
pectin methyltransferase ( Glycine max )
homogalacturonan methyltransferase ( Nicotiana tabacum )
methyl-H4SPT:CoM methyltransferase ( Methanosarcina thermophila )
methyl-H4SPT:CoM methyltransferase ( Methanosarcina barkeri )
flavonol 6-O-methyltransferase ( Rudbeckia hirta )
noraucuparin O-methyltransferase: OMT2 ( Sorbus aucuparia )
SAM:β-peltatin 6-O-methyltransferase ( Linum nodiflorum )
phosphodolichol-tetrasaccharide glucuronate methyltransferase: aglP ( Haloferax volcanii )
matairesinol 4-O-methyltransferase: FkOMT72 ( Forsythia viridissima koreana )
gingerol synthase: PKS ( Zingiber officinale )
flavonol 3'/5'-methyltransferase: MOMT1 ( Solanum habrochaites )
isoandrocymbine O-methyltransferase ( Colchicum autumnale )
demethylmacrocin O-methyltransferase: tylE ( Streptomyces fradiae )
flavonoid 4'-O-methyltransferase: FOMT5 ( Ocimum basilicum )
flavonoid 4'-O-methyltransferase: FOMT3 ( Ocimum basilicum )
C4-methyltransferase ( Arabidopsis thaliana col )
tetracenomycin B3 9-O-methyltransferase: elmP ( Streptomyces olivaceus )
L-leucyldemethyl-blasticidin S guanidino methyltransferase: blsL ( Streptomyces griseochromogenes )
o-dihydric phenol O-methyltransferase (para-methylation) ( Nicotiana tabacum )
flavonoid 7-O-methyltransferase: FOMT2 ( Ocimum basilicum )
flavonoid 7-O-methyltransferase: FOMT1 ( Ocimum basilicum )
flavonoid 7-O-methyltransferase: POMT-7 ( Populus deltoides )
flavonoid 7-O-methyltransferase: F1-OMT ( Hordeum vulgare )
L-leucyl-demethylarginomycin methyltransferase: argL ( Streptomyces arginensis )
nor-rubrofusarin O-methyltransferase: aurJ ( Fusarium graminearum )
5-hydroxymethylcytosine O-methyltransferase: bcmC ( Clostridium botulinum A str. ATCC 19397 )
thujaplicatin 5-O-methyltransferase: JOMT ( Anthriscus sylvestris )
vanillate/3-O-methylgallate O-demethylase: ligM ( Sphingomonas sp. SYK6 )
ethanolamine N-methyltransferase ( Ricinus communis )
trichosetin N-methyltransferase: eqxD ( Fusarium heterosporum )
methyl-quercetin/quercetagetin 3'/5'-O-methyltransferase: fomt1 ( Chrysosplenium americanum )
7'-O-demethylcephaeline 7'-O-methyltransferase: IpeOMT2 ( Carapichea ipecacuanha )
3'-O-demethyl-4'-N-demethyl-staurosporine methyltransferase: staMA ( Streptomyces sp. TP-A0274 )
5-hydroxy-desmethylanthrotainin 8-O-methyltransferase: VrtF ( Penicillium aethiopicum )
flavonoid 8-O-methyltransferase: F8OMT-1 ( Ocimum basilicum )
canadine N-methyltransferase / tetrahydroprotoberberine cis-N-methyltransferase: TNMT ( Papaver somniferum )
tetrahydroprotoberberine-cis-N-methyltransferase ( Eschscholzia californica )
caffeoyl-CoA O-methyltransferase [multifunctional]: At1G67990 ( Arabidopsis thaliana col )
12-demethyl-elloramycin C12a O-methyltransferase: elmD ( Streptomyces olivaceus )
2-methylbacteriohopanetetrol synthase [multifunctional]: hpnP ( Rhodopseudomonas palustris TIE-1 )
bikaverin O-methyltransferase: bik3 ( Fusarium fujikuroi )
hydroxyneurosporene methyltransferase: crtF ( Rhodobacter capsulatus )
flavonol 3-O-methyltransferase: MOMT3 ( Solanum habrochaites )
flavonol 3-O-methyltransferase: MOMT3 ( Solanum lycopersicum )
methyl-quercetin/quercetagetin glucoside 2'/3'-Omethyltransferase ( Chrysosplenium americanum )
6-O-methyldeacetylisoipecoside aglycon 7-O-methyltransferase: IpeOMT3 ( Carapichea ipecacuanha )
gibberellin carboxyl methyltransferase: GAMT2 ( Arabidopsis thaliana col )
bixin methyltransferase / norbixin methyltransferase: nBMT ( Bixa orellana )
tetracenomycin E C-9 O-methyltransferase: tcmP ( Streptomyces glaucescens )
3-methoxy-5-hydroxytoluene O-methyltransferase [multifunctional]: OOMT2 ( Rosa hybrid cultivar )
3-methoxy-5-hydroxytoluene O-methyltransferase [multifunctional]: OOMT1 ( Rosa hybrid cultivar )
3,5-dimethoxyphenol O-methyltransferase [multifunctional]: RcOMT2 ( Rosa chinensis )
flavonoid O-methyltransferase: OMT2 ( Triticum aestivum )
fusarubinaldehyde O-methyltransferase: fsr2 ( Fusarium fujikuroi )
dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose C3-methyltransferase: evaC ( Amycolatopsis orientalis )
gentamycin X2 C-methyltransferase: gntK ( Micromonospora echinospora )
N-methyl-3-aminomethylindole N-methyltransferase [multifunctional]: HvCOMT ( Hordeum vulgare )
2-(2,4-dihydroxy-6-methylbenzoyl)benzene-1,3,5-triol 3-O-methyltransferase: GsfB ( Penicillium aethiopicum )
phenylpropanoid/flavonoid O-methyltransferase: PFOMT ( Mesembryanthemum crystallinum )
coniferyl alcohol 9-O-methyltransferase: CA9OMT ( Linum flavum )
coniferyl alcohol 9-O-methyltransferase: CA9OMT ( Linum nodiflorum )
cis-vaccenate 11-methyltransferase: ufaM ( Rhodobacter sphaeroides )
3,5-dihydroxybiphenyl O-methyltransferase: OMT1 ( Sorbus aucuparia )
dTDP-4-dehydro-β-L-rhamnose C5-methyltransferase: novU ( Actinoalloteichus cyanogriseus )
macrocin O-methyltransferase: tylF ( Streptomyces fradiae )
5-n-alk(en)ylresorcinol O-methyltransferase: sbOMT3 ( Sorghum bicolor )
multifunctional aromatase/3-O-methyl transferase TcmN: tcmN ( Streptomyces glaucescens )
tetracenomycin D3 3-O-methyltransferase: elmNII ( Streptomyces olivaceus )
tRNA m6t6A37 methyltransferase: trmO ( Escherichia coli K-12 substr. MG1655 )
23S rRNA m2A2503 methyltransferase and tRNA m2A37 methyltransferase: rlmN ( Escherichia coli K-12 substr. MG1655 )
esculetin-O-methyltransferase: POMT-9 ( Populus deltoides )
flavonol 7/4'-methyltransferase: MOMT2 ( Solanum habrochaites )
N-demethyllincomycin methyltransferase: lmbJ ( Streptomyces lincolnensis )
caffeoyl-CoA O-methyltransferase: CCoAOMT7 ( Arabidopsis thaliana col )
3,7dimethylquercetin/quercetagetin 4'-O-methyltransferase ( Chrysosplenium americanum )
roquefortine/glandicoline O- methyltransferase: roqN ( Penicillium chrysogenum )
griseofulvin 5-O-methyltransferase: GsfD ( Penicillium aethiopicum )
DMMF:SAM-O-methyltransferase: FaOMT ( Fragaria x ananassa )
1-hydroxy-carotenoid methylase: crtF ( Rubrivivax gelatinosus )
5-methylthujaplicatin 4-O-methyltransferase ( Anthriscus sylvestris )
norreticuline 7-O-methyltransferase: N7OMT ( Papaver somniferum )
ethanolamine N-methyltransferase ( Ricinus communis )
dithiolgliotoxin S-methyltransferase: TmtA ( Aspergillus fumigatus )
flavonoid 6-O-methyltransferase: FOMT6 ( Ocimum basilicum )
flavonoid 6-O-methyltransferase: FOMT4 ( Ocimum basilicum )
methylquercetagetin-O-methyltransferase ( Chrysosplenium americanum )
methylquercetagetin 6-O-methyltransferase ( Chrysosplenium americanum )
cephaeline O-methyltransferase / 7'-O-demethylcephaeline 7'-O-methyltransferase: CiOMT1 ( Carapichea ipecacuanha )
cephaeline 6'-O-methyltransferase / deacetylisoipecoside 6-O-methyltransferase: IpeOMT1 ( Carapichea ipecacuanha )
phenylpropanoid and flavonoid O-methyltransferase: PFOMT-1 ( Ocimum basilicum )
dTDP-3-amino-4-oxo-2,3,6-trideoxy-α-D-glucose N,N-dimethyltransferase: megDIII ( Micromonospora megalomicea )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed Feb 10, 2016, biocyc13.