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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc EC 2.5.1 -- Transferring alkyl or aryl groups, other than methyl groups

Parent Class: EC-Numbers 2 -- Transferases 2.5 -- Transferring alkyl or aryl groups, other than methyl groups

Instances:
2.5.1.1 -- dimethylallyltranstransferase ,
2.5.1.2 -- thiamine pyridinylase ,
2.5.1.3 -- thiamine-phosphate diphosphorylase ,
2.5.1.4 -- adenosylmethionine cyclotransferase ,
2.5.1.5 -- galactose-6-sulfurylase ,
2.5.1.6 -- methionine adenosyltransferase ,
2.5.1.7 -- UDP-N-acetylglucosamine 1-carboxyvinyltransferase ,
2.5.1.9 -- riboflavin synthase ,
2.5.1.10 -- (2E,6E)-farnesyl diphosphate synthase ,
2.5.1.15 -- dihydropteroate synthase ,
2.5.1.16 -- spermidine synthase ,
2.5.1.17 -- cob(I)yrinic acid a,c-diamide adenosyltransferase ,
2.5.1.18 -- glutathione transferase ,
2.5.1.19 -- 3-phosphoshikimate 1-carboxyvinyltransferase ,
2.5.1.20 -- rubber cis-polyprenylcistransferase ,
2.5.1.21 -- squalene synthase ,
2.5.1.22 -- spermine synthase ,
2.5.1.23 -- sym-norspermidine synthase ,
2.5.1.24 -- discadenine synthase ,
2.5.1.25 -- tRNA-uridine aminocarboxypropyltransferase ,
2.5.1.26 -- alkylglycerone-phosphate synthase ,
2.5.1.27 -- adenylate dimethylallyltransferase ,
2.5.1.28 -- dimethylallylcistransferase ,
2.5.1.29 -- geranylgeranyl diphosphate synthase ,
2.5.1.30 -- heptaprenyl diphosphate synthase ,
2.5.1.31 -- ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] ,
2.5.1.32 -- 15-cis-phytoene synthase ,
2.5.1.34 -- 4-dimethylallyltryptophan synthase ,
2.5.1.35 -- aspulvinone dimethylallyltransferase ,
2.5.1.36 -- trihydroxypterocarpan dimethylallyltransferase ,
2.5.1.38 -- isonocardicin synthase ,
2.5.1.39 -- 4-hydroxybenzoate polyprenyltransferase ,
2.5.1.41 -- phosphoglycerol geranylgeranyltransferase ,
2.5.1.42 -- geranylgeranylglycerol-phosphate geranylgeranyltransferase ,
2.5.1.43 -- nicotianamine synthase ,
2.5.1.44 -- homospermidine synthase ,
2.5.1.45 -- homospermidine synthase (spermidine-specific) ,
2.5.1.46 -- deoxyhypusine synthase ,
2.5.1.47 -- cysteine synthase ,
2.5.1.48 -- cystathionine γ-synthase ,
2.5.1.49 -- O-acetylhomoserine aminocarboxypropyltransferase ,
2.5.1.50 -- zeatin 9-aminocarboxyethyltransferase ,
2.5.1.51 -- β-pyrazolylalanine synthase ,
2.5.1.52 -- L-mimosine synthase ,
2.5.1.53 -- uracilylalanine synthase ,
2.5.1.54 -- 3-deoxy-7-phosphoheptulonate synthase ,
2.5.1.55 -- 3-deoxy-8-phosphooctulonate synthase ,
2.5.1.56 -- N-acetylneuraminate synthase ,
2.5.1.57 -- N-acylneuraminate-9-phosphate synthase ,
2.5.1.58 -- protein farnesyltransferase ,
2.5.1.59 -- protein geranylgeranyltransferase type I ,
2.5.1.60 -- protein geranylgeranyltransferase type II ,
2.5.1.61 -- hydroxymethylbilane synthase ,
2.5.1.62 -- chlorophyll synthase ,
2.5.1.63 -- adenosyl-fluoride synthase ,
2.5.1.65 -- O-phosphoserine sulfhydrylase ,
2.5.1.66 -- N2-(2-carboxyethyl)arginine synthase ,
2.5.1.67 -- chrysanthemyl diphosphate synthase ,
2.5.1.68 -- (2Z,6E)-farnesyl diphosphate synthase ,
2.5.1.69 -- lavandulyl diphosphate synthase ,
2.5.1.70 -- naringenin 8-dimethylallyltransferase ,
2.5.1.71 -- leachianone-G 2′′-dimethylallyltransferase ,
2.5.1.72 -- quinolinate synthase ,
2.5.1.73 -- O-phospho-L-seryl-tRNA:Cys-tRNA synthase ,
2.5.1.74 -- 1,4-dihydroxy-2-naphthoate polyprenyltransferase ,
2.5.1.75 -- tRNA dimethylallyltransferase ,
2.5.1.76 -- cysteate synthase ,
2.5.1.77 -- 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase ,
2.5.1.78 -- 6,7-dimethyl-8-ribityllumazine synthase ,
2.5.1.79 -- thermospermine synthase ,
2.5.1.80 -- 7-dimethylallyltryptophan synthase ,
2.5.1.81 -- geranylfarnesyl diphosphate synthase ,
2.5.1.82 -- hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] ,
2.5.1.83 -- hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] ,
2.5.1.84 -- all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific] ,
2.5.1.85 -- all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] ,
2.5.1.86 -- trans,polycis-decaprenyl diphosphate synthase ,
2.5.1.87 -- ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] ,
2.5.1.88 -- trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] ,
2.5.1.89 -- tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] ,
2.5.1.90 -- all-trans-octaprenyl-diphosphate synthase ,
2.5.1.91 -- all-trans-decaprenyl-diphosphate synthase ,
2.5.1.92 -- (2Z,6Z)-farnesyl diphosphate synthase ,
2.5.1.93 -- 4-hydroxybenzoate geranyltransferase ,
2.5.1.94 -- adenosyl-chloride synthase ,
2.5.1.95 -- xanthan ketal pyruvate transferase ,
2.5.1.96 -- 4,4′-diapophytoene synthase ,
2.5.1.97 -- pseudaminic acid synthase ,
2.5.1.98 -- Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase ,
2.5.1.99 -- all-trans-phytoene synthase ,
2.5.1.100 -- fumigaclavine A dimethylallyltransferase ,
2.5.1.101 -- N,N′-diacetyllegionaminate synthase ,
2.5.1.102 -- geranyl-pyrophosphate—olivetolic acid geranyltransferase ,
2.5.1.103 -- presqualene diphosphate synthase ,
2.5.1.104 -- N1-aminopropylagmatine synthase ,
2.5.1.105 -- 7,8-dihydropterin-6-yl-methyl-4-(β-D-ribofuranosyl)aminobenzene 5′-phosphate synthase ,
2.5.1.106 -- tryprostatin B synthase ,
2.5.1.107 -- verruculogen prenyltransferase ,
2.5.1.108 -- 2-(3-amino-3-carboxypropyl)histidine synthase ,
2.5.1.109 -- brevianamide F prenyltransferase (deoxybrevianamide E-forming) ,
2.5.1.110 -- 12α,13α-dihydroxyfumitremorgin C prenyltransferase ,
2.5.1.111 -- 4-hydroxyphenylpyruvate 3-dimethylallyltransferase ,
2.5.1.112 -- adenylate dimethylallyltransferase (ADP/ATP-dependent) ,
2.5.1.113 -- [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase ,
2.5.1.114 -- tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase ,
2.5.1.115 -- homogentisate phytyltransferase ,
2.5.1.116 -- homogentisate geranylgeranyltransferase ,
2.5.1.117 -- homogentisate solanesyltransferase ,
2.5.1.118 -- β-(isoxazolin-5-on-2-yl)-L-alanine synthase ,
2.5.1.119 -- β-(isoxazolin-5-on-4-yl)-L-alanine synthase ,
2.5.1.120 -- aminodeoxyfutalosine synthase ,
2.5.1.121 -- 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase ,
2.5.1.122 -- 4-O-dimethylallyl-L-tyrosine synthase ,
2.5.1.123 -- flaviolin linalyltransferase ,
2.5.1.bg -- N4-bis(aminopropyl)spermidine synthase

Unofficial Reactions:
L-cysteine + O-phospho-L-homoserine → L-cystathionine + phosphate ,
heme b + (2E,6E)-farnesyl diphosphate + H2O ↔ heme o + diphosphate ,
all-trans-octaprenyl diphosphate + 1,4-dihydroxy-6-naphthoate + H+ → CO2 + demethylmenaquinol-8 + diphosphate ,
(2Z,6Z,10E)-tetraprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-pentaprenyl diphosphate + diphosphate ,
ω, mono-trans, poly-cis-pentaprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-hexaprenyl diphosphate + diphosphate ,
ω, mono-trans, poly-cis-hexaprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-heptaprenyl diphosphate + diphosphate ,
ω, mono-trans, poly-cis-heptaprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-octaprenyl diphosphate + diphosphate ,
ν-carrageenan → ι-carrageenose + 2 sulfate ,
geranylgeranyl diphosphate + 3 isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + 3 diphosphate ,
all-trans-3,4-didehydrolycopene → torulene ,
apo-4'-lycopenoate → neurosporaxanthin ,
D-Man-β-(1→4)-GlcA-β-(1→2)-D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphospho-ditrans,octacis-undecaprenol + phosphoenolpyruvate = 4,6-CH3(COO-)C-D-Man-β-(1→4)-GlcA-β-(1→2)-D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphospho-ditrans,octacis-undecaprenol + phosphate ,
L-selenocysteine + O-phospho-L-homoserine → L-selenocystathionine + phosphate ,
2,4,6-trihydroxybenzophenone + dimethylallyl diphosphate → hyperxanthone E + diphosphate ,
6-hydroxymethyl-7,8-dihydropterin + 4-aminobenzoate = 7,8-dihydropteroate + H2O ,
all-trans-hexaprenyl diphosphate + 4-aminobenzoate → 3-hexaprenyl-4-aminobenzoate + diphosphate ,
protocatechuate + all-trans-hexaprenyl diphosphate → 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + diphosphate ,
vanillate + all-trans-hexaprenyl diphosphate → 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + diphosphate ,
4-amino-3-methoxybenzoate + all-trans-hexaprenyl diphosphate → 3-hexaprenyl-4-amino-5-methoxybenzoate + diphosphate ,
all-trans-hexaprenyl diphosphate + 1,4-dihydroxy-6-naphthoate + H+ → CO2 + demethylmenaquinol-6 + diphosphate ,
(2E,6E)-farnesyl diphosphate + 2-methyl-4-hydroxyquinoline → aurachin D + diphosphate ,
4,6,8-trihydroxydibenzodiazepinone + (2E,6E)-farnesyl diphosphate = diazepinomicin + diphosphate ,
paxilline + 2 dimethylallyl diphosphate → 21,22-diprenylpaxilline + 2 diphosphate ,
fusicoccin P + dimethylallyl diphosphate → fusicoccin J + diphosphate ,
didemethylasterriquinone D + dimethylallyl diphosphate → asterriquinone C1 + diphosphate ,
ochrindole D + dimethylallyl diphosphate → terrequinone A + diphosphate ,
hydrodidemethylasterriquinone D + dimethylallyl diphosphate → ochrindole D + diphosphate + H2O ,
4-O-acetyl-N-acetylmannosamine + phosphoenolpyruvate + H2O → N-acetyl-7-O-acetylneuraminate + phosphate ,
(R)-benzodiazepinedione + dimethylallyl diphosphate → aszonalenin + diphosphate ,
paspalinine + dimethylallyl diphosphate → aflatrem + diphosphate ,
ardeemin FQ + dimethylallyl diphosphate → ardeemin + diphosphate ,
cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate → β-cyclopiazonate + diphosphate ,
2'-hydroxygenistein + dimethylallyl diphosphate → luteone + diphosphate ,
genistein + dimethylallyl diphosphate → wighteone + diphosphate ,
2'-hydroxygenistein + dimethylallyl diphosphate → 2,3-dehydrokievitone + diphosphate ,
1,4-dihydroxy-2-naphthoate + phytyl diphosphate + 3 H+ → CO2 + demethylphylloquinol + diphosphate ,
chlorophyllide a + geranylgeranyl diphosphate + H+ → geranylgeranyl-chlorophyll a + diphosphate ,
chlorophyllide b + geranylgeranyl diphosphate + H+ = geranylgeranyl-chlorophyll b + diphosphate ,
chlorophyllide b + phytyl diphosphate + H+ → chlorophyll b + diphosphate ,
2'-hydroxygenistein + dimethylallyl diphosphate → phaseoluteone + diphosphate ,
genistein + dimethylallyl diphosphate → isowighteone + diphosphate ,
genistein + dimethylallyl diphosphate → lupiwighteone + diphosphate ,
4-prenylphlorisovalerophenone + dimethylallyl diphosphate → diprenylphlorisovalerophenone + diphosphate ,
phlorisovalerophenone + dimethylallyl diphosphate → 4-prenylphlorisovalerophenone + diphosphate + H+ ,
phlorisobutyrophenone + dimethylallyl diphosphate → 4-prenylphlorisobutyrophenone + diphosphate + H+ ,
4-prenylphlorisobutyrophenone + dimethylallyl diphosphate → diprenylphlorisobutyrophenone + diphosphate ,
2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate → desmethylxanthohumol + diphosphate + H+ ,
olivetolate + neryl diphosphate = cannabinerolate + diphosphate ,
umbelliferone + dimethylallyl diphosphate → demethylsuberosin + diphosphate ,
2 (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate → (1R,6R)-1,2,5,5a,6,7-hexahydrophenazine-1,6-dicarboxylate + 2 H2O + 2 H+ ,
1,4-dihydroxy-2-naphthoate + dimethylallyl diphosphate → alizarin ,
(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = all-trans-undecaprenyl diphosphate + 8 diphosphate ,
(2E,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate = all-trans-dodecaprenyl diphosphate + 9 diphosphate ,
(2E,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate = all-trans-tridecaprenyl diphosphate + 10 diphosphate ,
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + diphosphate ,
cadaverine + S-adenosyl 3-(methylthio)propylamine → aminopropylcadaverine + S-methyl-5'-thioadenosine + H+ ,
di-trans-ply-cispolyisoprenyln-PP + isopentenyl diphosphate = di-trans-ply-cispolyisoprenyln+1-PP + diphosphate

Enzymes and Genes:
spermidine synthase : speE ( Escherichia coli K-12 substr. MG1655 )
rubber transferase ( Hevea brasiliensis )
PhzA/B : phzA/B ( Burkholderia lata )
dimethylallyl diphosphate:umbelliferone dimethylallyltransferase ( Ammi majus )
NPP:olivetolate neryltransferase / GPP:olivetolate geranyltransferase ( Cannabis sativa )
prenyltransferase ( Humulus lupulus )
phlorisobutyrophenone dimethylallyltransferase ( Hypericum calycinum )
phlorisobutyrophenone dimethylallyltransferase ( Humulus lupulus )
prenyltransferase ( Humulus lupulus )
prenyltransferase ( Humulus lupulus )
chlorophyll synthetase : G4 ( Arabidopsis thaliana col )
1,4-dihydroxy-2-naphthoate phytyltransferase : menA ( Synechocystis sp. PCC 6803 )
DHNA phytyl transferase : ABC4 ( Arabidopsis thaliana col )
DMAPP:isoflavone dimethylallyl transferase ( Lupinus albus )
cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase : CpaD ( Aspergillus oryzae )
ardeemin FQ prenyltransferase : ardB ( Neosartorya fischeri )
dimethylallyl-diphosphate:paspalinine dimethylallyltransferase, AtmD : atmD ( Aspergillus flavus )
benzodiazepinedione prenyltransferase : AnaPT ( Neosartorya fischeri )
7-O-acetyl-N-acetylneuraminate synthase : neuB1 ( Aliivibrio salmonicida LFI1238 )
bisindolylquinone prenyltransferase : tdiB ( Aspergillus nidulans )
diterpene glucoside O-glucose prenyltransferase : PAPT ( Diaporthe amygdali )
paxilline prenyltransferase : paxD ( Penicillium paxilli ATCC 26601 )
ABBA prenyltransferase DzmP : dzmP ( Micromonospora sp. RV115 )
2-methyl-4-hydroxyquinoline farnesyltransferase : auaA ( Stigmatella aurantiaca Sg a15 )
2-methyl-4-hydroxy-quinoline farnesyltransferase : rauB ( Rhodococcus erythropolis JCM 6824 )
hexaprenyl-diphosphate hexaprenyltransferase : COQ2 ( Saccharomyces cerevisiae )
xanthan ketal pyruvate transferase : gumL ( Xanthomonas campestris )
apo-4'-lycopenoate cyclase / 3,4-didehydrolycopene cyclase : al-2 ( Neurospora crassa )
heptaprenyl diphosphate synthase : hepS , hepT ( Bacillus subtilis )
D-galactose-2,6-sulfurylase II ( Chondrus crispus )
D-galactose-2,6-sulfurylase I ( Chondrus crispus )
heme O synthase : cyoE ( Escherichia coli K-12 substr. MG1655 )
cystathionine γ-synthase / selenocystathione synthase : CGS1 ( Arabidopsis thaliana col )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC14A.