Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc EC 2.5.1 -- Transferring alkyl or aryl groups, other than methyl groups

Parent Class: EC-Numbers 2 -- Transferases 2.5 -- Transferring alkyl or aryl groups, other than methyl groups

Instances:
2.5.1.1 -- dimethylallyltranstransferase ,
2.5.1.2 -- thiamine pyridinylase ,
2.5.1.3 -- thiamine-phosphate diphosphorylase ,
2.5.1.4 -- adenosylmethionine cyclotransferase ,
2.5.1.5 -- galactose-6-sulfurylase ,
2.5.1.6 -- methionine adenosyltransferase ,
2.5.1.7 -- UDP-N-acetylglucosamine 1-carboxyvinyltransferase ,
2.5.1.9 -- riboflavin synthase ,
2.5.1.10 -- (2E,6E)-farnesyl diphosphate synthase ,
2.5.1.15 -- dihydropteroate synthase ,
2.5.1.16 -- spermidine synthase ,
2.5.1.17 -- cob(I)yrinic acid a,c-diamide adenosyltransferase ,
2.5.1.18 -- glutathione transferase ,
2.5.1.19 -- 3-phosphoshikimate 1-carboxyvinyltransferase ,
2.5.1.20 -- rubber cis-polyprenylcistransferase ,
2.5.1.21 -- squalene synthase ,
2.5.1.22 -- spermine synthase ,
2.5.1.23 -- sym-norspermidine synthase ,
2.5.1.24 -- discadenine synthase ,
2.5.1.25 -- tRNA-uridine aminocarboxypropyltransferase ,
2.5.1.26 -- alkylglycerone-phosphate synthase ,
2.5.1.27 -- adenylate dimethylallyltransferase ,
2.5.1.28 -- dimethylallylcistransferase ,
2.5.1.29 -- geranylgeranyl diphosphate synthase ,
2.5.1.30 -- heptaprenyl diphosphate synthase ,
2.5.1.31 -- ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] ,
2.5.1.32 -- 15-cis-phytoene synthase ,
2.5.1.34 -- 4-dimethylallyltryptophan synthase ,
2.5.1.35 -- aspulvinone dimethylallyltransferase ,
2.5.1.36 -- trihydroxypterocarpan dimethylallyltransferase ,
2.5.1.38 -- isonocardicin synthase ,
2.5.1.39 -- 4-hydroxybenzoate polyprenyltransferase ,
2.5.1.41 -- phosphoglycerol geranylgeranyltransferase ,
2.5.1.42 -- geranylgeranylglycerol-phosphate geranylgeranyltransferase ,
2.5.1.43 -- nicotianamine synthase ,
2.5.1.44 -- homospermidine synthase ,
2.5.1.45 -- homospermidine synthase (spermidine-specific) ,
2.5.1.46 -- deoxyhypusine synthase ,
2.5.1.47 -- cysteine synthase ,
2.5.1.48 -- cystathionine γ-synthase ,
2.5.1.49 -- O-acetylhomoserine aminocarboxypropyltransferase ,
2.5.1.50 -- zeatin 9-aminocarboxyethyltransferase ,
2.5.1.51 -- β-pyrazolylalanine synthase ,
2.5.1.52 -- L-mimosine synthase ,
2.5.1.53 -- uracilylalanine synthase ,
2.5.1.54 -- 3-deoxy-7-phosphoheptulonate synthase ,
2.5.1.55 -- 3-deoxy-8-phosphooctulonate synthase ,
2.5.1.56 -- N-acetylneuraminate synthase ,
2.5.1.57 -- N-acylneuraminate-9-phosphate synthase ,
2.5.1.58 -- protein farnesyltransferase ,
2.5.1.59 -- protein geranylgeranyltransferase type I ,
2.5.1.60 -- protein geranylgeranyltransferase type II ,
2.5.1.61 -- hydroxymethylbilane synthase ,
2.5.1.62 -- chlorophyll synthase ,
2.5.1.63 -- adenosyl-fluoride synthase ,
2.5.1.65 -- O-phosphoserine sulfhydrylase ,
2.5.1.66 -- N2-(2-carboxyethyl)arginine synthase ,
2.5.1.67 -- chrysanthemyl diphosphate synthase ,
2.5.1.68 -- (2Z,6E)-farnesyl diphosphate synthase ,
2.5.1.69 -- lavandulyl diphosphate synthase ,
2.5.1.70 -- naringenin 8-dimethylallyltransferase ,
2.5.1.71 -- leachianone-G 2′′-dimethylallyltransferase ,
2.5.1.72 -- quinolinate synthase ,
2.5.1.73 -- O-phospho-L-seryl-tRNA:Cys-tRNA synthase ,
2.5.1.74 -- 1,4-dihydroxy-2-naphthoate polyprenyltransferase ,
2.5.1.75 -- tRNA dimethylallyltransferase ,
2.5.1.76 -- cysteate synthase ,
2.5.1.77 -- 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase ,
2.5.1.78 -- 6,7-dimethyl-8-ribityllumazine synthase ,
2.5.1.79 -- thermospermine synthase ,
2.5.1.80 -- 7-dimethylallyltryptophan synthase ,
2.5.1.81 -- geranylfarnesyl diphosphate synthase ,
2.5.1.82 -- hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] ,
2.5.1.83 -- hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] ,
2.5.1.84 -- all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific] ,
2.5.1.85 -- all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] ,
2.5.1.86 -- trans,polycis-decaprenyl diphosphate synthase ,
2.5.1.87 -- ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] ,
2.5.1.88 -- trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] ,
2.5.1.89 -- tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] ,
2.5.1.90 -- all-trans-octaprenyl-diphosphate synthase ,
2.5.1.91 -- all-trans-decaprenyl-diphosphate synthase ,
2.5.1.92 -- (2Z,6Z)-farnesyl diphosphate synthase ,
2.5.1.93 -- 4-hydroxybenzoate geranyltransferase ,
2.5.1.94 -- adenosyl-chloride synthase ,
2.5.1.95 -- xanthan ketal pyruvate transferase ,
2.5.1.96 -- 4,4′-diapophytoene synthase ,
2.5.1.97 -- pseudaminic acid synthase ,
2.5.1.98 -- Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase ,
2.5.1.99 -- all-trans-phytoene synthase ,
2.5.1.100 -- fumigaclavine A dimethylallyltransferase ,
2.5.1.101 -- N,N′-diacetyllegionaminate synthase ,
2.5.1.102 -- geranyl-pyrophosphate—olivetolic acid geranyltransferase ,
2.5.1.103 -- presqualene diphosphate synthase ,
2.5.1.104 -- N1-aminopropylagmatine synthase ,
2.5.1.105 -- 7,8-dihydropterin-6-yl-methyl-4-(β-D-ribofuranosyl)aminobenzene 5′-phosphate synthase ,
2.5.1.106 -- tryprostatin B synthase ,
2.5.1.107 -- verruculogen prenyltransferase ,
2.5.1.108 -- 2-(3-amino-3-carboxypropyl)histidine synthase ,
2.5.1.109 -- brevianamide F prenyltransferase (deoxybrevianamide E-forming) ,
2.5.1.110 -- 12α,13α-dihydroxyfumitremorgin C prenyltransferase ,
2.5.1.111 -- 4-hydroxyphenylpyruvate 3-dimethylallyltransferase ,
2.5.1.112 -- adenylate dimethylallyltransferase (ADP/ATP-dependent) ,
2.5.1.113 -- [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase ,
2.5.1.114 -- tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase ,
2.5.1.115 -- homogentisate phytyltransferase ,
2.5.1.116 -- homogentisate geranylgeranyltransferase ,
2.5.1.117 -- homogentisate solanesyltransferase ,
2.5.1.118 -- β-(isoxazolin-5-on-2-yl)-L-alanine synthase ,
2.5.1.119 -- β-(isoxazolin-5-on-4-yl)-L-alanine synthase ,
2.5.1.120 -- aminodeoxyfutalosine synthase ,
2.5.1.121 -- 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase ,
2.5.1.122 -- 4-O-dimethylallyl-L-tyrosine synthase ,
2.5.1.123 -- flaviolin linalyltransferase ,
2.5.1.bg -- N4-bis(aminopropyl)spermidine synthase

Unofficial Reactions:
L-cysteine + O-phospho-L-homoserine → L-cystathionine + phosphate ,
heme b + (2E,6E)-farnesyl diphosphate + H2O ↔ heme o + diphosphate ,
all-trans-octaprenyl diphosphate + 1,4-dihydroxy-6-naphthoate + H+ → CO2 + demethylmenaquinol-8 + diphosphate ,
(2Z,6Z,10E)-tetraprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-pentaprenyl diphosphate + diphosphate ,
ω, mono-trans, poly-cis-pentaprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-hexaprenyl diphosphate + diphosphate ,
ω, mono-trans, poly-cis-hexaprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-heptaprenyl diphosphate + diphosphate ,
ω, mono-trans, poly-cis-heptaprenyl diphosphate + isopentenyl diphosphate = ω, mono-trans, poly-cis-octaprenyl diphosphate + diphosphate ,
ν-carrageenan → ι-carrageenose + 2 sulfate ,
geranylgeranyl diphosphate + 3 isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + 3 diphosphate ,
all-trans-3,4-didehydrolycopene → torulene ,
apo-4'-lycopenoate → neurosporaxanthin ,
D-Man-β-(1→4)-GlcA-β-(1→2)-D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphospho-ditrans,octacis-undecaprenol + phosphoenolpyruvate = 4,6-CH3(COO-)C-D-Man-β-(1→4)-GlcA-β-(1→2)-D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphospho-ditrans,octacis-undecaprenol + phosphate ,
L-selenocysteine + O-phospho-L-homoserine → L-selenocystathionine + phosphate ,
2,4,6-trihydroxybenzophenone + dimethylallyl diphosphate → hyperxanthone E + diphosphate ,
6-hydroxymethyl-7,8-dihydropterin + 4-aminobenzoate = 7,8-dihydropteroate + H2O ,
all-trans-hexaprenyl diphosphate + 4-aminobenzoate → 3-hexaprenyl-4-aminobenzoate + diphosphate ,
protocatechuate + all-trans-hexaprenyl diphosphate → 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + diphosphate ,
vanillate + all-trans-hexaprenyl diphosphate → 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + diphosphate ,
4-amino-3-methoxybenzoate + all-trans-hexaprenyl diphosphate → 3-hexaprenyl-4-amino-5-methoxybenzoate + diphosphate ,
all-trans-hexaprenyl diphosphate + 1,4-dihydroxy-6-naphthoate + H+ → demethylmenaquinol-6 + CO2 + diphosphate ,
(2E,6E)-farnesyl diphosphate + 2-methyl-4-hydroxyquinoline → aurachin D + diphosphate ,
4,6,8-trihydroxydibenzodiazepinone + (2E,6E)-farnesyl diphosphate = diazepinomicin + diphosphate ,
paxilline + 2 dimethylallyl diphosphate → 21,22-diprenylpaxilline + 2 diphosphate ,
fusicoccin P + dimethylallyl diphosphate → fusicoccin J + diphosphate ,
didemethylasterriquinone D + dimethylallyl diphosphate → asterriquinone C1 + diphosphate ,
ochrindole D + dimethylallyl diphosphate → terrequinone A + diphosphate ,
hydrodidemethylasterriquinone D + dimethylallyl diphosphate → ochrindole D + diphosphate + H2O ,
4-O-acetyl-N-acetylmannosamine + phosphoenolpyruvate + H2O → N-acetyl-7-O-acetylneuraminate + phosphate ,
(R)-benzodiazepinedione + dimethylallyl diphosphate → aszonalenin + diphosphate ,
paspalinine + dimethylallyl diphosphate → aflatrem + diphosphate ,
ardeemin FQ + dimethylallyl diphosphate → ardeemin + diphosphate ,
cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate → β-cyclopiazonate + diphosphate ,
2'-hydroxygenistein + dimethylallyl diphosphate → luteone + diphosphate ,
genistein + dimethylallyl diphosphate → wighteone + diphosphate ,
2'-hydroxygenistein + dimethylallyl diphosphate → 2,3-dehydrokievitone + diphosphate ,
1,4-dihydroxy-2-naphthoate + phytyl diphosphate + 3 H+ → demethylphylloquinol + CO2 + diphosphate ,
chlorophyllide a + geranylgeranyl diphosphate + H+ → geranylgeranyl-chlorophyll a + diphosphate ,
chlorophyllide b + geranylgeranyl diphosphate + H+ = geranylgeranyl-chlorophyll b + diphosphate ,
chlorophyllide b + phytyl diphosphate + H+ → chlorophyll b + diphosphate ,
2'-hydroxygenistein + dimethylallyl diphosphate → phaseoluteone + diphosphate ,
genistein + dimethylallyl diphosphate → isowighteone + diphosphate ,
genistein + dimethylallyl diphosphate → lupiwighteone + diphosphate ,
4-prenylphlorisovalerophenone + dimethylallyl diphosphate → diprenylphlorisovalerophenone + diphosphate ,
phlorisovalerophenone + dimethylallyl diphosphate → 4-prenylphlorisovalerophenone + diphosphate + H+ ,
phlorisobutyrophenone + dimethylallyl diphosphate → 4-prenylphlorisobutyrophenone + diphosphate + H+ ,
4-prenylphlorisobutyrophenone + dimethylallyl diphosphate → diprenylphlorisobutyrophenone + diphosphate ,
2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate → desmethylxanthohumol + diphosphate + H+ ,
olivetolate + neryl diphosphate = cannabinerolate + diphosphate ,
umbelliferone + dimethylallyl diphosphate → demethylsuberosin + diphosphate ,
2 (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate → (1R,6R)-1,2,5,5a,6,7-hexahydrophenazine-1,6-dicarboxylate + 2 H2O + 2 H+ ,
1,4-dihydroxy-2-naphthoate + dimethylallyl diphosphate → alizarin ,
(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = all-trans-undecaprenyl diphosphate + 8 diphosphate ,
(2E,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate = all-trans-dodecaprenyl diphosphate + 9 diphosphate ,
(2E,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate = all-trans-tridecaprenyl diphosphate + 10 diphosphate ,
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + diphosphate ,
cadaverine + S-adenosyl 3-(methylthio)propylamine → aminopropylcadaverine + S-methyl-5'-thioadenosine + H+ ,
di-trans-ply-cispolyisoprenyln-PP + isopentenyl diphosphate = di-trans-ply-cispolyisoprenyln+1-PP + diphosphate

Enzymes and Genes:
spermidine synthase : speE ( Escherichia coli K-12 substr. MG1655 )
rubber transferase ( Hevea brasiliensis )
PhzA/B : phzA/B ( Burkholderia lata )
dimethylallyl diphosphate:umbelliferone dimethylallyltransferase ( Ammi majus )
NPP:olivetolate neryltransferase / GPP:olivetolate geranyltransferase ( Cannabis sativa )
prenyltransferase ( Humulus lupulus )
phlorisobutyrophenone dimethylallyltransferase ( Hypericum calycinum )
phlorisobutyrophenone dimethylallyltransferase ( Humulus lupulus )
prenyltransferase ( Humulus lupulus )
prenyltransferase ( Humulus lupulus )
chlorophyll synthetase : G4 ( Arabidopsis thaliana col )
1,4-dihydroxy-2-naphthoate phytyltransferase : menA ( Synechocystis sp. PCC 6803 )
DHNA phytyl transferase : ABC4 ( Arabidopsis thaliana col )
DMAPP:isoflavone dimethylallyl transferase ( Lupinus albus )
cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase : CpaD ( Aspergillus oryzae )
ardeemin FQ prenyltransferase : ardB ( Neosartorya fischeri )
dimethylallyl-diphosphate:paspalinine dimethylallyltransferase, AtmD : atmD ( Aspergillus flavus )
benzodiazepinedione prenyltransferase : AnaPT ( Neosartorya fischeri )
7-O-acetyl-N-acetylneuraminate synthase : neuB1 ( Aliivibrio salmonicida LFI1238 )
bisindolylquinone prenyltransferase : tdiB ( Aspergillus nidulans )
diterpene glucoside O-glucose prenyltransferase : PAPT ( Diaporthe amygdali )
paxilline prenyltransferase : paxD ( Penicillium paxilli ATCC 26601 )
ABBA prenyltransferase DzmP : dzmP ( Micromonospora sp. RV115 )
2-methyl-4-hydroxyquinoline farnesyltransferase : auaA ( Stigmatella aurantiaca Sg a15 )
2-methyl-4-hydroxy-quinoline farnesyltransferase : rauB ( Rhodococcus erythropolis JCM 6824 )
hexaprenyl-diphosphate hexaprenyltransferase : COQ2 ( Saccharomyces cerevisiae )
xanthan ketal pyruvate transferase : gumL ( Xanthomonas campestris )
apo-4'-lycopenoate cyclase / 3,4-didehydrolycopene cyclase : al-2 ( Neurospora crassa )
heptaprenyl diphosphate synthase : hepS , hepT ( Bacillus subtilis )
D-galactose-2,6-sulfurylase II ( Chondrus crispus )
D-galactose-2,6-sulfurylase I ( Chondrus crispus )
heme O synthase : cyoE ( Escherichia coli K-12 substr. MG1655 )
cystathionine γ-synthase / selenocystathione synthase : CGS1 ( Arabidopsis thaliana col )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, BIOCYC13A.