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MetaCyc EC 2.6.1 -- Transaminases (aminotransferases)

Parent Class: EC-Numbers 2 -- Transferases 2.6 -- Transferring nitrogenous groups

Instances:
2.6.1.1 -- aspartate transaminase ,
2.6.1.2 -- alanine transaminase ,
2.6.1.3 -- cysteine transaminase ,
2.6.1.4 -- glycine transaminase ,
2.6.1.5 -- tyrosine transaminase ,
2.6.1.6 -- leucine transaminase ,
2.6.1.7 -- kynurenine—oxoglutarate transaminase ,
2.6.1.8 -- 2,5-diaminovalerate transaminase ,
2.6.1.9 -- histidinol-phosphate transaminase ,
2.6.1.11 -- acetylornithine transaminase ,
2.6.1.12 -- alanine—oxo-acid transaminase ,
2.6.1.13 -- ornithine aminotransferase ,
2.6.1.14 -- asparagine—oxo-acid transaminase ,
2.6.1.15 -- glutamine—pyruvate transaminase ,
2.6.1.16 -- glutamine—fructose-6-phosphate transaminase (isomerizing) ,
2.6.1.17 -- succinyldiaminopimelate transaminase ,
2.6.1.18 -- β-alanine—pyruvate transaminase ,
2.6.1.19 -- 4-aminobutyrate—2-oxoglutarate transaminase ,
2.6.1.21 -- D-amino-acid transaminase ,
2.6.1.22 -- (S)-3-amino-2-methylpropionate transaminase ,
2.6.1.23 -- 4-hydroxyglutamate transaminase ,
2.6.1.24 -- diiodotyrosine transaminase ,
2.6.1.26 -- thyroid-hormone transaminase ,
2.6.1.27 -- tryptophan transaminase ,
2.6.1.28 -- tryptophan—phenylpyruvate transaminase ,
2.6.1.29 -- diamine transaminase ,
2.6.1.30 -- pyridoxamine—pyruvate transaminase ,
2.6.1.31 -- pyridoxamine—oxaloacetate transaminase ,
2.6.1.32 -- valine—3-methyl-2-oxovalerate transaminase ,
2.6.1.33 -- dTDP-4-amino-4,6-dideoxy-D-glucose transaminase ,
2.6.1.34 -- UDP-N-acetylbacillosamine transaminase ,
2.6.1.35 -- glycine—oxaloacetate transaminase ,
2.6.1.36 -- L-lysine 6-transaminase ,
2.6.1.37 -- 2-aminoethylphosphonate—pyruvate transaminase ,
2.6.1.38 -- histidine transaminase ,
2.6.1.39 -- 2-aminoadipate transaminase ,
2.6.1.40 -- (R)-3-amino-2-methylpropionate—pyruvate transaminase ,
2.6.1.41 -- D-methionine—pyruvate transaminase ,
2.6.1.42 -- branched-chain-amino-acid transaminase ,
2.6.1.43 -- aminolevulinate transaminase ,
2.6.1.44 -- alanine—glyoxylate transaminase ,
2.6.1.45 -- serine—glyoxylate transaminase ,
2.6.1.46 -- diaminobutyrate—pyruvate transaminase ,
2.6.1.47 -- alanine—oxomalonate transaminase ,
2.6.1.48 -- 5-aminovalerate transaminase ,
2.6.1.49 -- dihydroxyphenylalanine transaminase ,
2.6.1.50 -- glutamine—scyllo-inositol transaminase ,
2.6.1.51 -- serine—pyruvate transaminase ,
2.6.1.52 -- phosphoserine transaminase ,
2.6.1.54 -- pyridoxamine-phosphate transaminase ,
2.6.1.55 -- taurine—2-oxoglutarate transaminase ,
2.6.1.56 -- 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase ,
2.6.1.57 -- aromatic-amino-acid transaminase ,
2.6.1.58 -- phenylalanine(histidine) transaminase ,
2.6.1.59 -- dTDP-4-amino-4,6-dideoxygalactose transaminase ,
2.6.1.60 -- aromatic-amino-acid—glyoxylate transaminase ,
2.6.1.62 -- adenosylmethionine—8-amino-7-oxononanoate transaminase ,
2.6.1.63 -- kynurenine—glyoxylate transaminase ,
2.6.1.64 -- glutamine—phenylpyruvate transaminase ,
2.6.1.65 -- N6-acetyl-β-lysine transaminase ,
2.6.1.66 -- valine—pyruvate transaminase ,
2.6.1.67 -- 2-aminohexanoate transaminase ,
2.6.1.68 -- ornithine(lysine) transaminase ,
2.6.1.70 -- aspartate—phenylpyruvate transaminase ,
2.6.1.71 -- lysine—pyruvate 6-transaminase ,
2.6.1.72 -- D-4-hydroxyphenylglycine transaminase ,
2.6.1.73 -- methionine—glyoxylate transaminase ,
2.6.1.74 -- cephalosporin-C transaminase ,
2.6.1.75 -- cysteine-conjugate transaminase ,
2.6.1.76 -- diaminobutyrate—2-oxoglutarate transaminase ,
2.6.1.77 -- taurine—pyruvate aminotransferase ,
2.6.1.78 -- aspartate—prephenate aminotransferase ,
2.6.1.79 -- glutamate—prephenate aminotransferase ,
2.6.1.80 -- nicotianamine aminotransferase ,
2.6.1.81 -- succinylornithine transaminase ,
2.6.1.82 -- putrescine aminotransferase ,
2.6.1.83 -- LL-diaminopimelate aminotransferase ,
2.6.1.84 -- arginine—pyruvate transaminase ,
2.6.1.85 -- aminodeoxychorismate synthase ,
2.6.1.86 -- 2-amino-4-deoxychorismate synthase ,
2.6.1.87 -- UDP-4-amino-4-deoxy-L-arabinose aminotransferase ,
2.6.1.88 -- methionine transaminase ,
2.6.1.89 -- dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose transaminase ,
2.6.1.90 -- dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose transaminase ,
2.6.1.92 -- UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine transaminase ,
2.6.1.93 -- neamine transaminase ,
2.6.1.94 -- 2′-deamino-2′-hydroxyneamine transaminase ,
2.6.1.95 -- neomycin C transaminase ,
2.6.1.96 -- 4-aminobutyrate—pyruvate transaminase ,
2.6.1.97 -- archaeosine synthase ,
2.6.1.98 -- UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase ,
2.6.1.99 -- L-tryptophan—pyruvate aminotransferase ,
2.6.1.100 -- L-glutamine:2-deoxy-scyllo-inosose aminotransferase ,
2.6.1.101 -- L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase ,
2.6.1.102 -- GDP-perosamine synthase ,
2.6.1.103 -- (S)-3,5-dihydroxyphenylglycine transaminase ,
2.6.1.104 -- 3-dehydro-glucose-6-phosphate—glutamate transaminase ,
2.6.1.105 -- lysine—8-amino-7-oxononanoate transaminase ,
2.6.1.106 -- dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase ,
2.6.1.107 -- β-methylphenylalanine transaminase ,
2.6.1.x -- 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate transaminase

Unofficial Reactions:
deamino α-keto demethylphosphinothricin + an aminated amino group donor ↔ demethyl-phosphinothricin + a deaminated amino group donor ,
5-guanidino-3-methyl-2-oxo-pentanoate + L-aspartate ↔ 3-methylarginine + oxaloacetate ,
2-oxo-10-methylthiodecanoate + a standard α amino acid ↔ hexahomomethionine + a 2-oxo carboxylate ,
vanillin + an aminated amino group donor ↔ vanillylamine + a deaminated amino group donor ,
GDP-2-acetamido-2,6-dideoxy-α-D-xylo-hexos-4-ulose + L-glutamate ↔ GDP-4-amino-4,6-dideoxy-α-D-N-acetylglucosamine + 2-oxoglutarate ,
2-oxo-7-methylthioheptanoate + a standard α amino acid ↔ trihomomethionine + a 2-oxo carboxylate ,
(S)-methylmalonate-semialdehyde + L-alanine ↔ (S)-3-amino-2-methylpropanoate + pyruvate ,
L-alanine + glycerone phosphate ↔ serinol phosphate + pyruvate ,
N6-acetyl-L-lysine + 2-oxoglutarate ↔ L-glutamate + 2-keto-6-acetamidocaproate ,
6-aminohexanoate + 2-oxoglutarate ↔ 6-oxohexanoate + L-glutamate ,
2-oxohexa-4,5-cyclopropyl-5-enoate + an aminated amino group donor ↔ L-α-(methylenecyclopropyl)-glycine + a deaminated amino group donor ,
2-oxo-5-methylthiopentanoate + a standard α amino acid ↔ L-homomethionine + a 2-oxo carboxylate ,
1-amino-2-phosphorylethylphosphonate + 2-oxoglutarate ↔ 1-oxo-2-phosphorylethylphosphonate + L-glutamate ,
dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose + 2-oxoglutarate ↔ dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose + L-glutamate ,
D-fructose 6-phosphate + L-glutamate → 2-amino-2-deoxy-mannitol-6-phosphate + 2-oxoglutarate ,
L-arginine + a deaminated amino group donor ↔ 5-guanidino-2-oxo-pentanoate + an aminated amino group donor ,
putrescine + pyruvate ↔ 4-aminobutanal + L-alanine ,
cytosyl-4'-dehydro-β-D-glucuronate + an aminated amino group donor → cytosyl-4'-amino-β-D-glucuronate + a deaminated amino group donor ,
5-acetamidovalerate + 2-oxoglutarate + H2O ↔ L-glutamate + glutarate semialdehyde + acetate ,
2-oxoglutarate + an aminated amino group donor ↔ L-glutamate + a deaminated amino group donor ,
2-oxo-4-phosphonobutanoate + an aminated amino group donor ↔ 2-amino-4-phosphonobutanoate + a deaminated amino group donor ,
UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex4-ulose + L-glutamate → UDP-acetamido-4-amino-6-deoxygalactopyranose + 2-oxoglutarate ,
2-keto-4-hydroxy-5-phosphonopentanoate + an L-amino acid → 2-amino-4-hydroxy-5-phosphonopentanoate + a 2-oxo carboxylate ,
2-oxo-8-methylthiooctanoate + a standard α amino acid ↔ tetrahomomethionine + a 2-oxo carboxylate ,
2-keto-5-phosphono-3-cis-pentenoate + an L-amino acid → L-2-amino-5-phosphono-3-cis-pentenoate + a 2-oxo carboxylate ,
isobutanal + L-alanine ↔ 2-methylpropanamine + pyruvate ,
homotaurine + 2-oxoglutarate ↔ 3-sulfopropanal + L-glutamate ,
L-asparagine + glyoxylate ↔ 2-oxosuccinamate + glycine ,
paromomycin + 2-oxoglutarate ↔ 6'''-oxoparomomycin + L-glutamate ,
3-[(1S)-cyclohex-3-en-1-yl)]-2-oxopropanoate + an aminated amino group donor ↔ L-3-cyclohex-2'-enylalanine + a deaminated amino group donor ,
GDP-3-dehydro-6-deoxy-α-D-mannose + an aminated amino group donor → GDP-mycosamine + a deaminated amino group donor ,
3-sulfinoalanine + 2-oxoglutarate ↔ L-glutamate + 3-sulfinopyruvate ,
L-alanine + 5-oxooctanal ↔ 8-aminooctan-4-one + pyruvate ,
a [LysW]-C-terminal-L-glutamyl-γ-L-lysine + 2-oxoglutarate ↔ a [LysW]-C-terminal-L-glutamyl-γ-L-2-aminoadipate semialdehyde + L-glutamate ,
4-(4-hydroxyphenyl)-2-oxobutanoate + an amino acid → L-homotyrosine + a 2-oxo acid ,
2-oxo-9-methylthiononanoate + a standard α amino acid ↔ pentahomomethionine + a 2-oxo carboxylate ,
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-phenylalanine ↔ L-dihydroanticapsin + 2-oxo-3-phenylpropanoate ,
(S)-3-acetyloctanal + an L-amino acid → 2-methyl-3-n-amyl-dihydropyrrole + a 2-oxo acid + H2O ,
L-arginine + 2-oxoglutarate ↔ L-glutamate + 5-guanidino-2-oxo-pentanoate ,
2-oxo-6-methylthiohexanoate + a standard α amino acid ↔ L-dihomomethionine + a 2-oxo carboxylate ,
2-oxo-3-phenylpropanoate + L-tyrosine ↔ L-phenylalanine + 4-hydroxyphenylpyruvate ,
L-methionine + 2-oxoglutaramate ↔ 2-oxo-4-methylthiobutanoate + L-glutamine ,
an aminated amino group donor + 2-oxobutanoate = 2-aminobutanoate + a deaminated amino group donor ,
beta-methylenecyclopropyl pyruvate + L-alanine ↔ hypoglycin A + pyruvate ,
UDP-3-dehydro-α-D-glucose + L-glutamine ↔ UDP-α-D-kanosamine + 2-oxoglutaramate ,
cadaverine + a deaminated amino group donor ↔ 1-piperideine + an aminated amino group donor + H2O + H+

Enzymes and Genes:
L-lysine aminotransferase ( Pseudomonas aeruginosa )
3-amino-5-hydroxybenzoate synthase : rifK ( Amycolatopsis mediterranei )
β-methylenecyclopropyl-pyruvate aminotransferase ( Blighia sapida )
valine-pyruvate aminotransferase : avtA ( Escherichia coli K-12 substr. MG1655 )
2-oxo-4-methylthiobutanoate-glutamine aminotransferase : Solyc11g013170.1 ( Solanum lycopersicum )
2-oxo-4-methylthiobutanoate-glutamine aminotransferase : mtnE ( Bacillus subtilis subtilis 168 )
kynurenine aminotransferase I : CCBL1 ( Homo sapiens )
aromatic amino acid transaminase : ArAT1 ( Cucumis melo )
aromatic amino acid transaminase : PPY-AT ( Petunia x hybrida )
L-arginine transaminase : argM ( Streptomyces arginensis )
arginine-α-ketoglutarate transaminase ( Pimelobacter simplex )
(S)-3-acetyloctanal aminotransferase : pigE ( Serratia marcescens )
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate aminotransferase : bacF ( Bacillus subtilis )
4-(4-hydroxyphenyl)-2-oxobutanoate transaminase : HtyB ( Aspergillus rugulosus )
[LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase : lysJ ( Sulfolobus acidocaldarius )
[LysW]-L-2-aminoadipate semialdehyde transaminase : lysJ ( Thermus thermophilus )
L-alanine:5-ketooctanal aminotransferase B ( Conium maculatum )
L-alanine:5-ketooctanal aminotransferase A ( Conium maculatum )
aspartate aminotransferase 1 : GOT1 ( Homo sapiens )
aspartate transaminase [multifunctional] : Got1 ( Rattus norvegicus )
GDP-3-dehydro-6-deoxymannose aminotransferase : fscMII ( Streptomyces sp. FR-008 )
3-[(1S)-cyclohex-3-en-1-yl)]-2-oxopropanoate aminotransferase : salW ( Salinispora tropica )
glutamate--6'-oxoparomomycin aminotransferase : livB ( Streptomyces lividus )
asparagine aminotransferase ( Pisum sativum )
4-aminobutyrate aminotransferase : gabT ( Ralstonia eutropha H16 )
amine:pyruvate transaminase : HQ418483 ( Vibrio fluvialis JS17 )
L-α-amino acid transaminase : rhiJ ( Bacillus subtilis spizizenii ATCC 6633 )
UDP-acetamido-4-amino-6-deoxygalactopyranose transaminase : wcfR ( Bacteroides fragilis NCTC 9343 )
cytosyl-4'-dehydro-β-D-glucuronate transaminase : blsH ( Streptomyces griseochromogenes )
cytosyl-4'-dehydro-β-D-glucuronate transaminase : argH ( Streptomyces arginensis )
polyamine aminotransferase ( Arthrobacter sp. TMP-1 )
putrescine aminotransferase : spuC ( Pseudomonas aeruginosa )
D-fructose-6-phosphate-L-glutamate transaminase : gabT1 ( Bacillus amyloliquefaciens plantarum FZB42 )
dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose transaminase : megDII ( Micromonospora megalomicea )
dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose aminotransferase : evaB ( Amycolatopsis orientalis )
1-oxo-2-phosphorylethylphosphonate transaminase : dhpD ( Streptomyces luridus )
branched-chain aminotransferase : BCAT3 ( Arabidopsis thaliana col )
N6-acetyllysine aminotransferase ( Candida maltosa L4 )
N6-acetyllysine aminotransferase ( Candida tropicalis )
dihydroxyacetone phosphate transaminase ( Saccharum officinarum )
PLP-dependent GDP-4-amino-4,6-dideoxy-α-D-N-acetylglucosamine aminotransferase : legC ( Campylobacter jejuni jejuni NCTC 11168 = ATCC 700819 )
vanillin aminotransferase : pAMT ( Capsicum chinense )
5-guanidino-3-methyl-2-oxo-pentanoate aminotransferase : mrsB ( Pseudomonas syringae pv. syringae )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Mon Aug 31, 2015, biocyc11.