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MetaCyc EC 2.6.1 -- Transaminases (aminotransferases)

Parent Class: EC-Numbers2 -- Transferases2.6 -- Transferring nitrogenous groups

Instances:
2.6.1.1 -- aspartate transaminase,
2.6.1.2 -- alanine transaminase,
2.6.1.3 -- cysteine transaminase,
2.6.1.4 -- glycine transaminase,
2.6.1.5 -- tyrosine transaminase,
2.6.1.6 -- leucine transaminase,
2.6.1.7 -- kynurenine—oxoglutarate transaminase,
2.6.1.8 -- 2,5-diaminovalerate transaminase,
2.6.1.9 -- histidinol-phosphate transaminase,
2.6.1.11 -- acetylornithine transaminase,
2.6.1.12 -- alanine—oxo-acid transaminase,
2.6.1.13 -- ornithine aminotransferase,
2.6.1.14 -- asparagine—oxo-acid transaminase,
2.6.1.15 -- glutamine—pyruvate transaminase,
2.6.1.16 -- glutamine—fructose-6-phosphate transaminase (isomerizing),
2.6.1.17 -- succinyldiaminopimelate transaminase,
2.6.1.18 -- β-alanine—pyruvate transaminase,
2.6.1.19 -- 4-aminobutyrate—2-oxoglutarate transaminase,
2.6.1.21 -- D-amino-acid transaminase,
2.6.1.22 -- (S)-3-amino-2-methylpropionate transaminase,
2.6.1.23 -- 4-hydroxyglutamate transaminase,
2.6.1.24 -- diiodotyrosine transaminase,
2.6.1.26 -- thyroid-hormone transaminase,
2.6.1.27 -- tryptophan transaminase,
2.6.1.28 -- tryptophan—phenylpyruvate transaminase,
2.6.1.29 -- diamine transaminase,
2.6.1.30 -- pyridoxamine—pyruvate transaminase,
2.6.1.31 -- pyridoxamine—oxaloacetate transaminase,
2.6.1.32 -- valine—3-methyl-2-oxovalerate transaminase,
2.6.1.33 -- dTDP-4-amino-4,6-dideoxy-D-glucose transaminase,
2.6.1.34 -- UDP-N-acetylbacillosamine transaminase,
2.6.1.35 -- glycine—oxaloacetate transaminase,
2.6.1.36 -- L-lysine 6-transaminase,
2.6.1.37 -- 2-aminoethylphosphonate—pyruvate transaminase,
2.6.1.38 -- histidine transaminase,
2.6.1.39 -- 2-aminoadipate transaminase,
2.6.1.40 -- (R)-3-amino-2-methylpropionate—pyruvate transaminase,
2.6.1.41 -- D-methionine—pyruvate transaminase,
2.6.1.42 -- branched-chain-amino-acid transaminase,
2.6.1.43 -- aminolevulinate transaminase,
2.6.1.44 -- alanine—glyoxylate transaminase,
2.6.1.45 -- serine—glyoxylate transaminase,
2.6.1.46 -- diaminobutyrate—pyruvate transaminase,
2.6.1.47 -- alanine—oxomalonate transaminase,
2.6.1.48 -- 5-aminovalerate transaminase,
2.6.1.49 -- dihydroxyphenylalanine transaminase,
2.6.1.50 -- glutamine—scyllo-inositol transaminase,
2.6.1.51 -- serine—pyruvate transaminase,
2.6.1.52 -- phosphoserine transaminase,
2.6.1.54 -- pyridoxamine-phosphate transaminase,
2.6.1.55 -- taurine—2-oxoglutarate transaminase,
2.6.1.56 -- 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase,
2.6.1.57 -- aromatic-amino-acid transaminase,
2.6.1.58 -- phenylalanine(histidine) transaminase,
2.6.1.59 -- dTDP-4-amino-4,6-dideoxygalactose transaminase,
2.6.1.60 -- aromatic-amino-acid—glyoxylate transaminase,
2.6.1.62 -- adenosylmethionine—8-amino-7-oxononanoate transaminase,
2.6.1.63 -- kynurenine—glyoxylate transaminase,
2.6.1.64 -- glutamine—phenylpyruvate transaminase,
2.6.1.65 -- N6-acetyl-β-lysine transaminase,
2.6.1.66 -- valine—pyruvate transaminase,
2.6.1.67 -- 2-aminohexanoate transaminase,
2.6.1.68 -- ornithine(lysine) transaminase,
2.6.1.70 -- aspartate—phenylpyruvate transaminase,
2.6.1.71 -- lysine—pyruvate 6-transaminase,
2.6.1.72 -- D-4-hydroxyphenylglycine transaminase,
2.6.1.73 -- methionine—glyoxylate transaminase,
2.6.1.74 -- cephalosporin-C transaminase,
2.6.1.75 -- cysteine-conjugate transaminase,
2.6.1.76 -- diaminobutyrate—2-oxoglutarate transaminase,
2.6.1.77 -- taurine—pyruvate aminotransferase,
2.6.1.78 -- aspartate—prephenate aminotransferase,
2.6.1.79 -- glutamate—prephenate aminotransferase,
2.6.1.80 -- nicotianamine aminotransferase,
2.6.1.81 -- succinylornithine transaminase,
2.6.1.82 -- putrescine aminotransferase,
2.6.1.83 -- LL-diaminopimelate aminotransferase,
2.6.1.84 -- arginine—pyruvate transaminase,
2.6.1.85 -- aminodeoxychorismate synthase,
2.6.1.86 -- 2-amino-4-deoxychorismate synthase,
2.6.1.87 -- UDP-4-amino-4-deoxy-L-arabinose aminotransferase,
2.6.1.88 -- methionine transaminase,
2.6.1.89 -- dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose transaminase,
2.6.1.90 -- dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose transaminase,
2.6.1.92 -- UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine transaminase,
2.6.1.93 -- neamine transaminase,
2.6.1.94 -- 2′-deamino-2′-hydroxyneamine transaminase,
2.6.1.95 -- neomycin C transaminase,
2.6.1.96 -- 4-aminobutyrate—pyruvate transaminase,
2.6.1.97 -- archaeosine synthase,
2.6.1.98 -- UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase,
2.6.1.99 -- L-tryptophan—pyruvate aminotransferase,
2.6.1.100 -- L-glutamine:2-deoxy-scyllo-inosose aminotransferase,
2.6.1.101 -- L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase,
2.6.1.102 -- GDP-perosamine synthase,
2.6.1.103 -- (S)-3,5-dihydroxyphenylglycine transaminase,
2.6.1.104 -- 3-dehydro-glucose-6-phosphate—glutamate transaminase,
2.6.1.105 -- lysine—8-amino-7-oxononanoate transaminase,
2.6.1.106 -- dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase,
2.6.1.107 -- β-methylphenylalanine transaminase,
2.6.1.108 -- 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate transaminase,
2.6.1.109 -- 8-amino-3,8-dideoxy-D-manno-octulosonate transaminase

Unofficial Reactions:
a [LysW]-C-terminal-L-glutamyl-γ-L-lysine + 2-oxoglutarate ↔ a [LysW]-C-terminal-L-glutamyl-γ-L-2-aminoadipate semialdehyde + L-glutamate,
an aminated amino group donor + 2-oxobutanoate = 2-aminobutanoate + a deaminated amino group donor,
2-oxohexa-4,5-cyclopropyl-5-enoate + an aminated amino group donor ↔ L-α-(methylenecyclopropyl)-glycine + a deaminated amino group donor,
L-methionine + 2-oxoglutaramate ↔ 2-oxo-4-methylthiobutanoate + L-glutamine,
2-oxoglutarate + an aminated amino group donor ↔ L-glutamate + a deaminated amino group donor,
5-guanidino-3-methyl-2-oxo-pentanoate + L-aspartate ↔ 3-methylarginine + oxaloacetate,
(S)-3-acetyloctanal + an L-amino acid → 2-methyl-3-n-amyl-dihydropyrrole + a 2-oxo acid + H2O,
1-amino-2-phosphorylethylphosphonate + 2-oxoglutarate ↔ 1-oxo-2-phosphorylethylphosphonate + L-glutamate,
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-phenylalanine ↔ L-dihydroanticapsin + 2-oxo-3-phenylpropanoate,
L-arginine + 2-oxoglutarate ↔ L-glutamate + 5-guanidino-2-oxo-pentanoate,
UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-idosamine + 2-oxoglutarate ↔ UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hexul-4-ose + L-glutamate,
5-acetamidovalerate + 2-oxoglutarate + H2O ↔ L-glutamate + glutarate semialdehyde + acetate,
2-oxo-8-methylthiooctanoate + a standard α amino acid ↔ tetrahomomethionine + a 2-oxo carboxylate,
N6-acetyl-L-lysine + 2-oxoglutarate ↔ L-glutamate + 2-keto-6-acetamidocaproate,
cadaverine + a deaminated amino group donor ↔ 1-piperideine + an aminated amino group donor + H2O + H+,
2-oxo-4-phosphonobutanoate + an aminated amino group donor ↔ 2-amino-4-phosphonobutanoate + a deaminated amino group donor,
(R)-β-hydroxy-L-kynurenine + 2-oxoglutarate → (3R)-4-(2-aminophenyl)-3-hydroxy-2,4-dioxobutanoate + L-glutamate,
3-sulfinoalanine + 2-oxoglutarate ↔ L-glutamate + 3-sulfinopyruvate,
vanillin + an aminated amino group donor ↔ vanillylamine + a deaminated amino group donor,
L-serine + ammonium → (S)-2,3-diaminopropanoate + H2O,
GDP-2-acetamido-2,6-dideoxy-α-D-xylo-hexos-4-ulose + L-glutamate ↔ GDP-4-amino-4,6-dideoxy-α-D-N-acetylglucosamine + 2-oxoglutarate,
dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose + 2-oxoglutarate ↔ dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose + L-glutamate,
homotaurine + 2-oxoglutarate ↔ 3-sulfopropanal + L-glutamate,
GDP-3-dehydro-6-deoxy-α-D-mannose + an aminated amino group donor → GDP-mycosamine + a deaminated amino group donor,
2-keto-5-phosphono-3-cis-pentenoate + an L-amino acid → L-2-amino-5-phosphono-3-cis-pentenoate + a 2-oxo carboxylate,
beta-methylenecyclopropyl pyruvate + L-alanine ↔ hypoglycin A + pyruvate,
(S)-methylmalonate-semialdehyde + L-alanine ↔ (S)-3-amino-2-methylpropanoate + pyruvate,
2-oxo-5-methylthiopentanoate + a standard α amino acid ↔ L-homomethionine + a 2-oxo carboxylate,
2-keto-4-hydroxy-5-phosphonopentanoate + an L-amino acid → 2-amino-4-hydroxy-5-phosphonopentanoate + a 2-oxo carboxylate,
UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex4-ulose + L-glutamate → UDP-acetamido-4-amino-6-deoxygalactopyranose + 2-oxoglutarate,
2-oxo-7-methylthioheptanoate + a standard α amino acid ↔ trihomomethionine + a 2-oxo carboxylate,
cytosyl-4'-dehydro-β-D-glucuronate + an aminated amino group donor → cytosyl-4'-amino-β-D-glucuronate + a deaminated amino group donor,
2-oxo-10-methylthiodecanoate + a standard α amino acid ↔ hexahomomethionine + a 2-oxo carboxylate,
4-hydroxy-4-methyl-2-oxoglutarate + an L-amino acid → 4-hydroxy-4-methylglutamate + a 2-oxo carboxylate,
L-arginine + a deaminated amino group donor ↔ 5-guanidino-2-oxo-pentanoate + an aminated amino group donor,
D-fructose 6-phosphate + L-glutamate → 2-amino-2-deoxy-mannitol-6-phosphate + 2-oxoglutarate,
L-alanine + 5-oxooctanal ↔ 8-aminooctan-4-one + pyruvate,
putrescine + pyruvate ↔ 4-aminobutanal + L-alanine,
2-oxo-3-phenylpropanoate + L-tyrosine ↔ L-phenylalanine + 4-hydroxyphenylpyruvate,
UDP-3-dehydro-α-D-glucose + L-glutamine ↔ UDP-α-D-kanosamine + 2-oxoglutaramate,
L-asparagine + glyoxylate ↔ 2-oxosuccinamate + glycine,
2-oxo-6-methylthiohexanoate + a standard α amino acid ↔ L-dihomomethionine + a 2-oxo carboxylate,
3-[(1S)-cyclohex-3-en-1-yl)]-2-oxopropanoate + an aminated amino group donor ↔ L-3-cyclohex-2'-enylalanine + a deaminated amino group donor,
4-(4-hydroxyphenyl)-2-oxobutanoate + an amino acid → L-homotyrosine + a 2-oxo acid,
isobutanal + L-alanine ↔ 2-methylpropanamine + pyruvate,
paromomycin + 2-oxoglutarate ↔ 6'''-oxoparomomycin + L-glutamate,
2-oxo-9-methylthiononanoate + a standard α amino acid ↔ pentahomomethionine + a 2-oxo carboxylate,
deamino α-keto demethylphosphinothricin + an aminated amino group donor ↔ demethyl-L-phosphinothricin + a deaminated amino group donor,
L-alanine + glycerone phosphate ↔ serinol phosphate + pyruvate,
6-aminohexanoate + 2-oxoglutarate ↔ 6-oxohexanoate + L-glutamate

Enzymes and Genes:
dihydroxyacetone phosphate transaminase ( Saccharum officinarum )
glutamate--6'-oxoparomomycin aminotransferase: livB ( Streptomyces lividus )
amine:pyruvate transaminase: HQ418483 ( Vibrio fluvialis JS17 )
4-(4-hydroxyphenyl)-2-oxobutanoate transaminase: HtyB ( Aspergillus rugulosus )
3-[(1S)-cyclohex-3-en-1-yl)]-2-oxopropanoate aminotransferase: salW ( Salinispora tropica )
asparagine aminotransferase ( Pisum sativum )
3-amino-5-hydroxybenzoate synthase: rifK ( Amycolatopsis mediterranei )
aromatic amino acid transaminase: ArAT1 ( Cucumis melo )
aromatic amino acid transaminase: PPY-AT ( Petunia x hybrida )
polyamine aminotransferase ( Arthrobacter sp. TMP-1 )
putrescine aminotransferase: spuC ( Pseudomonas aeruginosa )
L-alanine:5-ketooctanal aminotransferase B ( Conium maculatum )
L-alanine:5-ketooctanal aminotransferase A ( Conium maculatum )
D-fructose-6-phosphate-L-glutamate transaminase: gabT1 ( Bacillus methylotrophicus FZB42 )
cytosyl-4'-dehydro-β-D-glucuronate transaminase: blsH ( Streptomyces griseochromogenes )
cytosyl-4'-dehydro-β-D-glucuronate transaminase: argH ( Streptomyces arginensis )
UDP-acetamido-4-amino-6-deoxygalactopyranose transaminase: wcfR ( Bacteroides fragilis NCTC 9343 )
branched-chain aminotransferase: BCAT3 ( Arabidopsis thaliana col )
β-methylenecyclopropyl-pyruvate aminotransferase ( Blighia sapida )
L-α-amino acid transaminase: rhiJ ( Bacillus subtilis spizizenii ATCC 6633 )
GDP-3-dehydro-6-deoxymannose aminotransferase: fscMII ( Streptomyces sp. FR-008 )
4-aminobutyrate aminotransferase: gabT ( Ralstonia eutropha H16 )
dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose transaminase: megDII ( Micromonospora megalomicea )
dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose aminotransferase: evaB ( Amycolatopsis orientalis )
PLP-dependent GDP-4-amino-4,6-dideoxy-α-D-N-acetylglucosamine aminotransferase: legC ( Campylobacter jejuni jejuni NCTC 11168 = ATCC 700819 )
L-serine aminase: zmaU ( Bacillus cereus )
vanillin aminotransferase: pAMT ( Capsicum chinense )
aspartate aminotransferase 1: GOT1 ( Homo sapiens )
aspartate transaminase [multifunctional]: Got1 ( Rattus norvegicus )
(2S,3R)-4-(2-aminophenyl)-2-amino-3-hydroxy-4-oxobutanoate aminotransferase: swb1 ( Streptomyces sp. SNA15896 )
L-lysine aminotransferase ( Pseudomonas aeruginosa )
N6-acetyllysine aminotransferase ( Candida maltosa L4 )
N6-acetyllysine aminotransferase ( Candida tropicalis )
UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-idosamine transaminase: orf2 ( Escherichia coli O108 )
L-arginine transaminase: argM ( Streptomyces arginensis )
arginine-α-ketoglutarate transaminase ( Pimelobacter simplex )
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate aminotransferase: bacF ( Bacillus subtilis )
1-oxo-2-phosphorylethylphosphonate transaminase: dhpD ( Streptomyces luridus )
(S)-3-acetyloctanal aminotransferase: pigE ( Serratia marcescens )
5-guanidino-3-methyl-2-oxo-pentanoate aminotransferase: mrsB ( Pseudomonas syringae pv. syringae )
2-oxo-4-methylthiobutanoate-glutamine aminotransferase: Solyc11g013170.1 ( Solanum lycopersicum )
2-oxo-4-methylthiobutanoate-glutamine aminotransferase: mtnE ( Bacillus subtilis subtilis 168 )
kynurenine aminotransferase I: CCBL1 ( Homo sapiens )
valine-pyruvate aminotransferase: avtA ( Escherichia coli K-12 substr. MG1655 )
[LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase: lysJ ( Sulfolobus acidocaldarius )
[LysW]-L-2-aminoadipate semialdehyde transaminase: lysJ ( Thermus thermophilus )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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