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MetaCyc EC 3.1.3 -- Phosphoric monoester hydrolases

Parent Class: EC-Numbers3 -- Hydrolases3.1 -- Acting on ester bonds

Instances:
3.1.3.1 -- alkaline phosphatase,
3.1.3.2 -- acid phosphatase,
3.1.3.3 -- phosphoserine phosphatase,
3.1.3.4 -- phosphatidate phosphatase,
3.1.3.5 -- 5′-nucleotidase,
3.1.3.6 -- 3′-nucleotidase,
3.1.3.7 -- 3′(2′),5′-bisphosphate nucleotidase,
3.1.3.8 -- 3-phytase,
3.1.3.9 -- glucose-6-phosphatase,
3.1.3.10 -- glucose-1-phosphatase,
3.1.3.11 -- fructose-bisphosphatase,
3.1.3.12 -- trehalose-phosphatase,
3.1.3.13 -- bisphosphoglycerate phosphatase,
3.1.3.14 -- methylphosphothioglycerate phosphatase,
3.1.3.15 -- histidinol-phosphatase,
3.1.3.16 -- protein-serine/threonine phosphatase,
3.1.3.17 -- [phosphorylase] phosphatase,
3.1.3.18 -- phosphoglycolate phosphatase,
3.1.3.19 -- glycerol-2-phosphatase,
3.1.3.20 -- phosphoglycerate phosphatase,
3.1.3.21 -- glycerol-1-phosphatase,
3.1.3.22 -- mannitol-1-phosphatase,
3.1.3.23 -- sugar-phosphatase,
3.1.3.24 -- sucrose-phosphate phosphatase,
3.1.3.25 -- inositol-phosphate phosphatase,
3.1.3.26 -- 4-phytase,
3.1.3.27 -- phosphatidylglycerophosphatase,
3.1.3.28 -- ADP-phosphoglycerate phosphatase,
3.1.3.29 -- N-acylneuraminate-9-phosphatase,
3.1.3.31 -- nucleotidase,
3.1.3.32 -- polynucleotide 3′-phosphatase,
3.1.3.33 -- polynucleotide 5′-phosphatase,
3.1.3.34 -- deoxynucleotide 3′-phosphatase,
3.1.3.35 -- thymidylate 5′-phosphatase,
3.1.3.36 -- phosphoinositide 5-phosphatase,
3.1.3.37 -- sedoheptulose-bisphosphatase,
3.1.3.38 -- 3-phosphoglycerate phosphatase,
3.1.3.39 -- streptomycin-6-phosphatase,
3.1.3.40 -- guanidinodeoxy-scyllo-inositol-4-phosphatase,
3.1.3.41 -- 4-nitrophenylphosphatase,
3.1.3.42 -- [glycogen-synthase-D] phosphatase,
3.1.3.43 -- [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase,
3.1.3.44 -- [acetyl-CoA carboxylase]-phosphatase,
3.1.3.45 -- 3-deoxy-manno-octulosonate-8-phosphatase,
3.1.3.46 -- fructose-2,6-bisphosphate 2-phosphatase,
3.1.3.47 -- [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase,
3.1.3.48 -- protein-tyrosine-phosphatase,
3.1.3.49 -- [pyruvate kinase]-phosphatase,
3.1.3.50 -- sorbitol-6-phosphatase,
3.1.3.51 -- dolichyl-phosphatase,
3.1.3.52 -- [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase,
3.1.3.53 -- [myosin-light-chain] phosphatase,
3.1.3.54 -- fructose-2,6-bisphosphate 6-phosphatase,
3.1.3.55 -- caldesmon-phosphatase,
3.1.3.56 -- inositol-polyphosphate 5-phosphatase,
3.1.3.57 -- inositol-1,4-bisphosphate 1-phosphatase,
3.1.3.58 -- sugar-terminal-phosphatase,
3.1.3.59 -- alkylacetylglycerophosphatase,
3.1.3.60 -- phosphoenolpyruvate phosphatase,
3.1.3.62 -- multiple inositol-polyphosphate phosphatase,
3.1.3.63 -- 2-carboxy-D-arabinitol-1-phosphatase,
3.1.3.64 -- phosphatidylinositol-3-phosphatase,
3.1.3.66 -- phosphatidylinositol-3,4-bisphosphate 4-phosphatase,
3.1.3.67 -- phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase,
3.1.3.68 -- 2-deoxyglucose-6-phosphatase,
3.1.3.69 -- glucosylglycerol 3-phosphatase,
3.1.3.70 -- mannosyl-3-phosphoglycerate phosphatase,
3.1.3.71 -- 2-phosphosulfolactate phosphatase,
3.1.3.72 -- 5-phytase,
3.1.3.73 -- adenosylcobalamin/α-ribazole phosphatase,
3.1.3.74 -- pyridoxal phosphatase,
3.1.3.75 -- phosphoethanolamine/phosphocholine phosphatase,
3.1.3.76 -- lipid-phosphate phosphatase,
3.1.3.77 -- acireductone synthase,
3.1.3.78 -- phosphatidylinositol-4,5-bisphosphate 4-phosphatase,
3.1.3.79 -- mannosylfructose-phosphate phosphatase,
3.1.3.80 -- 2,3-bisphosphoglycerate 3-phosphatase,
3.1.3.81 -- diacylglycerol diphosphate phosphatase,
3.1.3.82 -- D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase,
3.1.3.83 -- D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase,
3.1.3.84 -- ADP-ribose 1′′-phosphate phosphatase,
3.1.3.85 -- glucosyl-3-phosphoglycerate phosphatase,
3.1.3.86 -- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase,
3.1.3.87 -- 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase,
3.1.3.88 -- 5′′-phosphoribostamycin phosphatase,
3.1.3.89 -- 5′-deoxynucleotidase,
3.1.3.90 -- maltose 6′-phosphate phosphatase,
3.1.3.91 -- 7-methylguanosine nucleotidase,
3.1.3.92 -- kanosamine-6-phosphate phosphatase,
3.1.3.93 -- L-galactose 1-phosphate phosphatase,
3.1.3.94 -- D-galactose 1-phosphate phosphatase,
3.1.3.95 -- phosphatidylinositol-3,5-bisphosphate 3-phosphatase,
3.1.3.96 -- pseudouridine 5′-phosphatase,
3.1.3.97 -- 3',5'-nucleoside bisphosphate phosphatase,
3.1.3.u -- geranyl diphosphate phosphohydrolase,
3.1.3.v -- IMP-specific 5'-nucleotidase,
3.1.3.w -- thiamin phosphate phosphatase

Unofficial Reactions:
a 6-phosphogluco-3-phosphogluco-amylopectin + m+q H2O → a 6-phosphogluco-3-phosphogluco-amylopectin + m+q phosphate,
adenosine 2'-monophosphate[periplasm] + H2O[periplasm] → adenosine[periplasm] + phosphate[periplasm],
toyocamycin phosphate + H2O → toyocamycin + phosphate,
β-L-gulose 1-phosphate + H2O → L-gulopyranose + phosphate,
(-)-bornyl-diphosphate + H2O → (-)-borneol + diphosphate,
a 6-phosphogluco-3-phosphogluco-amylopectin + n H2O → an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin + n phosphate,
(2E,6E)-farnesyl phosphate + H2O → (2E,6E)-farnesol + phosphate,
L-threonine 3-O-phosphate[periplasm] + H2O[periplasm] → L-threonine[periplasm] + phosphate[periplasm],
archaetidylglycerol phosphate + H2O = unsaturated archaetidylglycerol + phosphate,
β-D-fructofuranose 1-phosphate + H2O → β-D-fructofuranose + phosphate,
geranyl monophosphate + H2O = geraniol + phosphate,
a 1-phosphatidyl-1D-myo-inositol 5-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate,
D-ribose 5-phosphate[periplasm] + H2O[periplasm]aldehydo-D-ribose[periplasm] + phosphate[periplasm],
a 6-phosphogluco-amylopectin + n H2O → a 6-phosphogluco-amylopectin + n phosphate,
2-phospho-L-ascorbate + H2O → L-ascorbate + phosphate,
diethylphosphate + H2O → ethylphosphate + ethanol + H+,
2-amino-2-deoxy-mannitol-6-phosphate + H2O → 2-amino-2-deoxy-D-mannitol + phosphate,
guanosine 2'-monophosphate[periplasm] + H2O[periplasm] → guanosine[periplasm] + phosphate[periplasm],
an ecdysteroid 22-phosphate + H2O → an ecdysteroid + phosphate,
D-erythro-D-gluco-octose α-1,8-bisphosphate + H2O → D-erythro-D-gluco-octose α-1-phosphate + phosphate,
(+)-bornyl-diphosphate + H2O → (+)-borneol + diphosphate,
5-chloro-5-deoxyribose 1-phosphate + H2O → 5-chloro-5-deoxy-D-ribose + phosphate,
5''-phosphoribosylparomamine + H2O → 5-ribosylparomamine + phosphate,
a 6-phosphogluco-amylopectin[chloroplast stroma] + n H2O[chloroplast stroma] → an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin[chloroplast stroma] + n phosphate[chloroplast stroma],
D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (3,4,5,6)-tetrakisphosphate + phosphate,
D-myo-inositol (1,2) bisphosphate + H2O → 1D-myo-inositol 1-monophosphate + phosphate,
D-gluconate 6-phosphate + H2O → D-gluconate + phosphate,
a 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O → an L-1-phosphatidyl-inositol + phosphate,
NADPH + H2O → NADH + phosphate,
ecdysone 22-phosphate + H2O → ecdysone + phosphate,
serinol phosphate + H2O → serinol + phosphate,
D-myo-inositol (1,4,5,6)-tetrakisphosphate + H2O → D-myo-inositol (1,4,5)-trisphosphate + phosphate,
cytidine 2'-monophosphate[periplasm] + H2O[periplasm] → cytidine[periplasm] + phosphate[periplasm],
2-[2-O-(α-D-mannopyranosyl)-(1→2)-α-D-glucopyranosyl]-3-phospho-D-glycerate + H2O → 2-[2-O-(α-D-mannopyranosyl)-(1→2)-α-D-glucopyranosyl]-D-glycerate + phosphate,
cysteamine S-phosphate[periplasm] + H2O[periplasm] → cysteamine[periplasm] + phosphate[periplasm],
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate + H2O → [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol + phosphate,
phytosphingosine 1-phosphate + H2O → phytosphingosine + phosphate,
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O → a 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate,
sphinganine 1-phosphate + H2O → D-erythro-sphinganine + phosphate,
FMN + H2O → riboflavin + phosphate,
D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O → D-myo-inositol (1,4,5,6)-tetrakisphosphate + phosphate,
uridine 2'-monophosphate[periplasm] + H2O[periplasm] → uridine[periplasm] + phosphate[periplasm],
a phosphorylated isocitrate dehydrogenase + H2O → an isocitrate dehydrogenase + phosphate,
a [protein] L-threonine phosphate + H2O → a [protein]-L-threonine + phosphate,
a protein L-serine phosphate + H2O → a [protein]-L-serine + phosphate

Enzymes and Genes:
isocitrate dehydrogenase phosphatase / isocitrate dehydrogenase kinase: aceK ( Escherichia coli K-12 substr. MG1655 )
inositol phosphate phosphatase sopB: sopB ( Salmonella enterica )
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase: yigB ( Escherichia coli K-12 substr. MG1655 )
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase: ybjI ( Escherichia coli K-12 substr. MG1655 )
phosphatidylinositol 5-phosphatase: 5PTase11 ( Arabidopsis thaliana col )
phosphatidylinositol 3,5-bisphosphate 5-phosphatase: FIG4 ( Homo sapiens )
phosphatidylinositol 3,5-bisphosphate 5-phosphatase: FIG4 ( Saccharomyces cerevisiae )
sphingoid base phosphate phosphatase: LCB3 ( Saccharomyces cerevisiae )
sphingoid base phosphate phosphatase: YSR3 ( Saccharomyces cerevisiae )
glucosyl-3-phosphoglycerate phosphatase: mggB ( Petrotoga mobilis )
multiple inositol polyphosphate phosphatase 1: MINPP1 ( Homo sapiens )
serinol phosphate phosphatase ( Saccharum officinarum )
NADPH phosphatase ( Zea mays )
phosphatidylinositide phosphatase SAC1: SACM1L ( Homo sapiens )
phosphoinositide phosphatase: SAC1 ( Saccharomyces cerevisiae )
6-phosphogluconate phosphatase: yieH ( Escherichia coli K-12 substr. MG1655 )
purple acid phosphatase [multifunctional]: PAP12 ( Arabidopsis thaliana col )
purple acid phosphatase [multifunctional]: PAP26 ( Arabidopsis thaliana col )
inositol-polyphosphate kinase/phosphatase: ITPK1 ( Homo sapiens )
5''-phosphoribosylparomamine phosphatase: livP ( Streptomyces lividus )
5-chloro-5-deoxyribose 1 phosphate phosphatase: salN ( Salinispora tropica )
(+)-bornyl-diphosphate diphosphatase ( Salvia officinalis )
octose 1,8-bisphosphate phosphatase: lmbK ( Streptomyces lincolnensis )
ecdysteroid-phosphate phosphatase: LOC692444 ( Bombyx mori )
2-amino-2-deoxy-mannitol-6-phosphatase: yktc1 ( Bacillus methylotrophicus FZB42 )
diethylphosphate phosphodiesterase: pdeA ( Delftia acidovorans )
phosphoinositide lipid phosphatase PLIP: PTPMT1 ( Homo sapiens )
fructose-1-phosphatase: yqaB ( Escherichia coli K-12 substr. MG1655 )
acid phosphatase / phosphotransferase: aphA ( Escherichia coli K-12 substr. MG1655 )
farnesyl phosphatase: CG15739 ( Drosophila melanogaster )
(-)-bornyl diphosphate hydrolase ( Tanacetum vulgare )
phosphosugar phosphatase: yigL ( Escherichia coli K-12 substr. MG1655 )
sugar phosphatase: yidA ( Escherichia coli K-12 substr. MG1655 )
sugar phosphatase: yfbT ( Escherichia coli K-12 substr. MG1655 )
sugar phosphatase: ybiV ( Escherichia coli K-12 substr. MG1655 )
toyocamycin phosphate phosphatase: toyI ( Streptomyces rimosus )
alkaline phosphatase: phoA ( Escherichia coli K-12 substr. MG1655 )
glucan phosphatase: SEX4 ( Arabidopsis thaliana col )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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