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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc EC 3.5.1 -- In linear amides

Parent Class: EC-Numbers 3 -- Hydrolases 3.5 -- Acting on carbon-nitrogen bonds, other than peptide bonds

Instances:
3.5.1.1 -- asparaginase ,
3.5.1.2 -- glutaminase ,
3.5.1.3 -- ω-amidase ,
3.5.1.4 -- amidase ,
3.5.1.5 -- urease ,
3.5.1.6 -- β-ureidopropionase ,
3.5.1.7 -- ureidosuccinase ,
3.5.1.8 -- formylaspartate deformylase ,
3.5.1.9 -- arylformamidase ,
3.5.1.10 -- formyltetrahydrofolate deformylase ,
3.5.1.11 -- penicillin amidase ,
3.5.1.12 -- biotinidase ,
3.5.1.13 -- aryl-acylamidase ,
3.5.1.14 -- N-acyl-aliphatic-L-amino acid amidohydrolase ,
3.5.1.15 -- aspartoacylase ,
3.5.1.16 -- acetylornithine deacetylase ,
3.5.1.17 -- acyl-lysine deacylase ,
3.5.1.18 -- succinyl-diaminopimelate desuccinylase ,
3.5.1.19 -- nicotinamidase ,
3.5.1.20 -- citrullinase ,
3.5.1.21 -- N-acetyl-β-alanine deacetylase ,
3.5.1.22 -- pantothenase ,
3.5.1.23 -- ceramidase ,
3.5.1.24 -- choloylglycine hydrolase ,
3.5.1.25 -- N-acetylglucosamine-6-phosphate deacetylase ,
3.5.1.26 -- N4-(β-N-acetylglucosaminyl)-L-asparaginase ,
3.5.1.27 -- N-formylmethionylaminoacyl-tRNA deformylase ,
3.5.1.28 -- N-acetylmuramoyl-L-alanine amidase ,
3.5.1.29 -- 2-(acetamidomethylene)succinate hydrolase ,
3.5.1.30 -- 5-aminopentanamidase ,
3.5.1.31 -- formylmethionine deformylase ,
3.5.1.32 -- hippurate hydrolase ,
3.5.1.33 -- N-acetylglucosamine deacetylase ,
3.5.1.35 -- D-glutaminase ,
3.5.1.36 -- N-methyl-2-oxoglutaramate hydrolase ,
3.5.1.38 -- glutamin-(asparagin-)ase ,
3.5.1.39 -- alkylamidase ,
3.5.1.40 -- acylagmatine amidase ,
3.5.1.41 -- chitin deacetylase ,
3.5.1.42 -- nicotinamide-nucleotide amidase ,
3.5.1.43 -- peptidyl-glutaminase ,
3.5.1.44 -- protein-glutamine glutaminase ,
3.5.1.46 -- 6-aminohexanoate-oligomer exohydrolase ,
3.5.1.47 -- N-acetyldiaminopimelate deacetylase ,
3.5.1.48 -- acetylspermidine deacetylase ,
3.5.1.49 -- formamidase ,
3.5.1.50 -- pentanamidase ,
3.5.1.51 -- 4-acetamidobutyryl-CoA deacetylase ,
3.5.1.52 -- peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase ,
3.5.1.53 -- N-carbamoylputrescine amidase ,
3.5.1.54 -- allophanate hydrolase ,
3.5.1.55 -- long-chain-fatty-acyl-glutamate deacylase ,
3.5.1.56 -- N,N-dimethylformamidase ,
3.5.1.57 -- tryptophanamidase ,
3.5.1.58 -- N-benzyloxycarbonylglycine hydrolase ,
3.5.1.59 -- N-carbamoylsarcosine amidase ,
3.5.1.60 -- N-(long-chain-acyl)ethanolamine deacylase ,
3.5.1.61 -- mimosinase ,
3.5.1.62 -- acetylputrescine deacetylase ,
3.5.1.63 -- 4-acetamidobutyrate deacetylase ,
3.5.1.64 -- Nα-benzyloxycarbonylleucine hydrolase ,
3.5.1.65 -- theanine hydrolase ,
3.5.1.66 -- 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase ,
3.5.1.67 -- 4-methyleneglutaminase ,
3.5.1.68 -- N-formylglutamate deformylase ,
3.5.1.69 -- glycosphingolipid deacylase ,
3.5.1.70 -- aculeacin-A deacylase ,
3.5.1.71 -- N-feruloylglycine deacylase ,
3.5.1.72 -- D-benzoylarginine-4-nitroanilide amidase ,
3.5.1.73 -- carnitinamidase ,
3.5.1.74 -- chenodeoxycholoyltaurine hydrolase ,
3.5.1.75 -- urethanase ,
3.5.1.76 -- arylalkyl acylamidase ,
3.5.1.77 -- N-carbamoyl-D-amino-acid hydrolase ,
3.5.1.78 -- glutathionylspermidine amidase ,
3.5.1.79 -- phthalyl amidase ,
3.5.1.81 -- N-acyl-D-amino-acid deacylase ,
3.5.1.82 -- N-acyl-D-glutamate deacylase ,
3.5.1.83 -- N-acyl-D-aspartate deacylase ,
3.5.1.84 -- biuret amidohydrolase ,
3.5.1.85 -- (S)-N-acetyl-1-phenylethylamine hydrolase ,
3.5.1.86 -- mandelamide amidase ,
3.5.1.87 -- N-carbamoyl-L-amino-acid hydrolase ,
3.5.1.88 -- peptide deformylase ,
3.5.1.89 -- N-acetylglucosaminylphosphatidylinositol deacetylase ,
3.5.1.90 -- adenosylcobinamide hydrolase ,
3.5.1.91 -- N-substituted formamide deformylase ,
3.5.1.92 -- pantetheine hydrolase ,
3.5.1.93 -- glutaryl-7-aminocephalosporanic-acid acylase ,
3.5.1.94 -- γ-glutamyl-γ-aminobutyrate hydrolase ,
3.5.1.95 -- N-malonylurea hydrolase ,
3.5.1.96 -- succinylglutamate desuccinylase ,
3.5.1.97 -- acyl-homoserine-lactone acylase ,
3.5.1.98 -- histone deacetylase ,
3.5.1.99 -- fatty acid amide hydrolase ,
3.5.1.100 -- (R)-amidase ,
3.5.1.101 -- L-proline amide hydrolase ,
3.5.1.102 -- 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase ,
3.5.1.103 -- N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase ,
3.5.1.104 -- peptidoglycan-N-acetylglucosamine deacetylase ,
3.5.1.105 -- chitin disaccharide deacetylase ,
3.5.1.106 -- N-formylmaleamate deformylase ,
3.5.1.107 -- maleamate amidohydrolase ,
3.5.1.108 -- UDP-3-O-acyl-N-acetylglucosamine deacetylase ,
3.5.1.109 -- sphingomyelin deacylase ,
3.5.1.110 -- peroxyureidoacrylate/ureidoacrylate amidohydrolase ,
3.5.1.111 -- 2-oxoglutaramate amidase ,
3.5.1.112 -- 2′-N-acetylparomamine deacetylase ,
3.5.1.113 -- 2′′′-acetyl-6′′′-hydroxyneomycin C deacetylase ,
3.5.1.114 -- N-acyl-aromatic-L-amino acid amidohydrolase ,
3.5.1.115 -- mycothiol S-conjugate amidase ,
3.5.1.116 -- ureidoglycolate amidohydrolase ,
3.5.1.117 -- 6-aminohexanoate-oligomer endohydrolase ,
3.5.1.w -- γ-glutamyl hercynylcysteine S-oxide hydrolase

Unofficial Reactions:
5-acetamidovalerate + H2O → 5-aminopentanoate + acetate ,
pyrazinamide + H2O = ammonium + pyrazine-2-carboxylate ,
4-ureido-5-imidazole carboxylate + H2O + 2 H+ → 4-amino-5-imidazole carboxylate + CO2 + ammonium ,
N,N'-diacetylchitobiose + H2O → 2-acetamido-4-O-(2-amino-2-deoxy-β-D-glucopyranosyl)-2-deoxy-D-glucose + acetate ,
formylaminopyrimidine + H2O → aminomethylpyrimidine + formate ,
N-monoacetylchitobiose + H2O = chitobiose + acetate ,
chitotriose + H2O = N,N''-diacetylchitotriose + acetate ,
2'''-acetyl-6'''-hydroxyparomomycin + H2O → 6'''-hydroxyparomomycin + acetate ,
N-formyldemecolcine + H2O → demecolcine + formate ,
4-hydroxy-2-nonenal-N-acetyl-L-cysteine + H2O = 4-hydroxy-2-nonenal-[L-Cys] conjugate + acetate ,
an [L-2-aminoadipate carrier protein]-L-ornithine + H2O → L-ornithine + a [LysW protein]-L-glutamate ,
(Z)-N,N'-(but-2-ene-2,3-diyl)diacetamide + H2O → N-(3-oxobutan-2-yl)acetamide + acetamide ,
N-(3-hydroxybutan-2-yl)acetamide + H2O → 3-amino-2-butanol + acetate ,
2-formylaminobenzaldehyde + H2O → O-aminobenzaldehyde + formate + H+ ,
γ-glutamylanilide diol + H2O → 1-aminocyclohexa-3,5-diene-1,2-diol + L-glutamate ,
N5-phenyl-L-glutamine + H2O → L-glutamate + aniline + H+ ,
linuron + H2O → N,O-dimethylhydroxylamine + CO2 + 3,4-dichloroaniline ,
indole-3-acetyl-alanine + H2O → indole-3-acetate + L-alanine ,
indole-3-acetyl-leucine + H2O → indole-3-acetate + L-leucine ,
a [LysW]-C-terminal-L-glutamyl-γ-L-lysine + H2O ↔ L-lysine + a [LysW protein]-L-glutamate ,
2-oxosuccinamate + H2O → oxaloacetate + ammonium ,
indole-3-acetyl-aspartate-N-beta-D-glucose + H2O → indole-3-acetyl-N-beta-D-glucose + L-aspartate ,
indole-3-acetyl-glutamate-N-beta-D-glucose + H2O → indole-3-acetyl-N-beta-D-glucose + L-glutamate ,
oxamate + H2O = oxalate + ammonium ,
p-aminobenzoyl glutamate + H2O → 4-aminobenzoate + L-glutamate ,
a [lipoyl-carrier protein] N6-lipoyl-L-lysine + H2O → a [lipoyl-carrier protein]-L-lysine + (R)-lipoate

Enzymes and Genes:
lipoamidase : lpa ( Enterococcus faecalis )
lipoamidase ( Listeria monocytogenes )
p-aminobenzoyl-glutamate hydrolase : abgB , abgA ( Escherichia coli K-12 substr. MG1655 )
p-aminobenzoylglutamate hydrolase ( Arabidopsis thaliana )
2-oxosuccinamate deamidase ( Pisum sativum )
[L-2-aminoadipate carrier protein]-L-lysine lysine-hydrolase : lysK ( Thermus thermophilus )
indole-3-acetyl-leu hydrolase : AT3G02875 ( Arabidopsis thaliana col )
indole-3-acetyl-ala hydrolase : ill2 ( Arabidopsis thaliana col )
indole-3-acetyl-ala hydrolase : iar3 ( Arabidopsis thaliana col )
phenylurea hydrolase A : puhA ( Arthrobacter globiformis D47 )
phenylurea hydrolase B : puhB ( Mycobacterium brisbanense JK1 )
linuron hydrolase : libA ( Variovorax sp. SRS16 )
linuron hydrolase : hylA ( Variovorax sp. WDL1 )
N-glutamylanilide hydrolase / N-glutamylanilide diol hydrolase : atdA2 ( Acinetobacter sp. YAA )
(Z)-N,N'-(but-2-ene-2,3-diyl)diacetamide hydrolase : tpdC ( Rhodococcus sp. TMP1 )
L-2-aminoadipate carrier protein]-lysine/ornithine hydrolase : lysK ( Sulfolobus acidocaldarius )
aminoacylase 3 : ACY3 ( Homo sapiens )
N-formyldemecolcine deformylase [multifunctional] ( Colchicum autumnale )
2'''-acetyl-6'''-hydroxyparomomycin deacetylase : livD ( Streptomyces lividus )
chitin oligosaccharide deacetylase : cod ( Vibrio cholerae O1 biovar El Tor str. N16961 )
N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase : ylmB ( Bacillus halodurans )
chitin deacetylase : cda ( Colletotrichum lindemuthianum )
diacetylchitobiose deacetylase : dac ( Thermococcus kodakarensis KOD1 )
4-ureido-5-imidazolecarboxylate amidohydrolase ( Clostridium cylindrosporum )
nicotinamidase / pyrazinamidase : pncA ( Escherichia coli K-12 substr. MG1655 )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, BIOCYC14A.