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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc EC 4.1.1 -- Carboxy-lyases

Parent Class: EC-Numbers 4 -- Lyases 4.1 -- Carbon-carbon lyases

Instances:
4.1.1.1 -- pyruvate decarboxylase ,
4.1.1.2 -- oxalate decarboxylase ,
4.1.1.3 -- oxaloacetate decarboxylase ,
4.1.1.4 -- acetoacetate decarboxylase ,
4.1.1.5 -- acetolactate decarboxylase ,
4.1.1.6 -- aconitate decarboxylase ,
4.1.1.7 -- benzoylformate decarboxylase ,
4.1.1.8 -- oxalyl-CoA decarboxylase ,
4.1.1.9 -- malonyl-CoA decarboxylase ,
4.1.1.11 -- aspartate 1-decarboxylase ,
4.1.1.12 -- aspartate 4-decarboxylase ,
4.1.1.14 -- valine decarboxylase ,
4.1.1.15 -- glutamate decarboxylase ,
4.1.1.16 -- hydroxyglutamate decarboxylase ,
4.1.1.17 -- ornithine decarboxylase ,
4.1.1.18 -- lysine decarboxylase ,
4.1.1.19 -- arginine decarboxylase ,
4.1.1.20 -- diaminopimelate decarboxylase ,
4.1.1.21 -- phosphoribosylaminoimidazole carboxylase ,
4.1.1.22 -- histidine decarboxylase ,
4.1.1.23 -- orotidine-5′-phosphate decarboxylase ,
4.1.1.24 -- aminobenzoate decarboxylase ,
4.1.1.25 -- tyrosine decarboxylase ,
4.1.1.28 -- aromatic-L-amino-acid decarboxylase ,
4.1.1.29 -- sulfinoalanine decarboxylase ,
4.1.1.30 -- pantothenoylcysteine decarboxylase ,
4.1.1.31 -- phosphoenolpyruvate carboxylase ,
4.1.1.32 -- phosphoenolpyruvate carboxykinase (GTP) ,
4.1.1.33 -- diphosphomevalonate decarboxylase ,
4.1.1.34 -- dehydro-L-gulonate decarboxylase ,
4.1.1.35 -- UDP-glucuronate decarboxylase ,
4.1.1.36 -- phosphopantothenoylcysteine decarboxylase ,
4.1.1.37 -- uroporphyrinogen decarboxylase ,
4.1.1.38 -- phosphoenolpyruvate carboxykinase (diphosphate) ,
4.1.1.39 -- ribulose-bisphosphate carboxylase ,
4.1.1.40 -- hydroxypyruvate decarboxylase ,
4.1.1.41 -- methylmalonyl-CoA decarboxylase ,
4.1.1.42 -- carnitine decarboxylase ,
4.1.1.43 -- phenylpyruvate decarboxylase ,
4.1.1.44 -- 4-carboxymuconolactone decarboxylase ,
4.1.1.45 -- aminocarboxymuconate-semialdehyde decarboxylase ,
4.1.1.46 -- o-pyrocatechuate decarboxylase ,
4.1.1.47 -- tartronate-semialdehyde synthase ,
4.1.1.48 -- indole-3-glycerol-phosphate synthase ,
4.1.1.49 -- phosphoenolpyruvate carboxykinase (ATP) ,
4.1.1.50 -- adenosylmethionine decarboxylase ,
4.1.1.51 -- 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase ,
4.1.1.52 -- 6-methylsalicylate decarboxylase ,
4.1.1.53 -- phenylalanine decarboxylase ,
4.1.1.54 -- dihydroxyfumarate decarboxylase ,
4.1.1.55 -- 4,5-dihydroxyphthalate decarboxylase ,
4.1.1.56 -- 3-oxolaurate decarboxylase ,
4.1.1.57 -- methionine decarboxylase ,
4.1.1.58 -- orsellinate decarboxylase ,
4.1.1.59 -- gallate decarboxylase ,
4.1.1.60 -- stipitatonate decarboxylase ,
4.1.1.61 -- 4-hydroxybenzoate decarboxylase ,
4.1.1.62 -- gentisate decarboxylase ,
4.1.1.63 -- protocatechuate decarboxylase ,
4.1.1.64 -- 2,2-dialkylglycine decarboxylase (pyruvate) ,
4.1.1.65 -- phosphatidylserine decarboxylase ,
4.1.1.66 -- uracil-5-carboxylate decarboxylase ,
4.1.1.67 -- UDP-galacturonate decarboxylase ,
4.1.1.68 -- 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase ,
4.1.1.69 -- 3,4-dihydroxyphthalate decarboxylase ,
4.1.1.70 -- glutaconyl-CoA decarboxylase ,
4.1.1.71 -- 2-oxoglutarate decarboxylase ,
4.1.1.72 -- branched-chain-2-oxoacid decarboxylase ,
4.1.1.73 -- tartrate decarboxylase ,
4.1.1.74 -- indolepyruvate decarboxylase ,
4.1.1.75 -- 5-guanidino-2-oxopentanoate decarboxylase ,
4.1.1.76 -- arylmalonate decarboxylase ,
4.1.1.77 -- 2-oxo-3-hexenedioate decarboxylase ,
4.1.1.78 -- acetylenedicarboxylate decarboxylase ,
4.1.1.79 -- sulfopyruvate decarboxylase ,
4.1.1.80 -- 4-hydroxyphenylpyruvate decarboxylase ,
4.1.1.81 -- threonine-phosphate decarboxylase ,
4.1.1.82 -- phosphonopyruvate decarboxylase ,
4.1.1.83 -- 4-hydroxyphenylacetate decarboxylase ,
4.1.1.84 -- D-dopachrome decarboxylase ,
4.1.1.85 -- 3-dehydro-L-gulonate-6-phosphate decarboxylase ,
4.1.1.86 -- diaminobutyrate decarboxylase ,
4.1.1.87 -- malonyl-S-ACP decarboxylase ,
4.1.1.88 -- biotin-independent malonate decarboxylase ,
4.1.1.89 -- biotin-dependent malonate decarboxylase ,
4.1.1.90 -- peptidyl-glutamate 4-carboxylase ,
4.1.1.91 -- salicylate decarboxylase ,
4.1.1.92 -- indole-3-carboxylate decarboxylase ,
4.1.1.93 -- pyrrole-2-carboxylate decarboxylase ,
4.1.1.94 -- ethylmalonyl-CoA decarboxylase ,
4.1.1.95 -- L-glutamyl-[BtrI acyl-carrier protein] decarboxylase ,
4.1.1.96 -- carboxynorspermidine decarboxylase ,
4.1.1.97 -- 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase ,
4.1.1.98 -- 4-hydroxy-3-polyprenylbenzoate decarboxylase

Unofficial Reactions:
2-oxopent-5-chloro-3-enoate + H+ → 2-oxo-5-chloro-4-pentenoate + CO2 ,
carboxyspermidine + H+ → spermidine + CO2 ,
5-chloro-4-hydroxy-2-oxopentanoate + an oxidized ferredoxin + coenzyme A → 4-chloro-3-hydroxybutyryl-CoA + CO2 + a reduced ferredoxin ,
a 3-oxoacid + H+ → a methylketone + CO2 ,
3-hexaprenyl-4-amino-5-methoxybenzoate + H+ → 2-hexaprenyl-6-methoxyaminobenzene + CO2 ,
10-carboxy-3-deoxycarminomycin + H+ → 13-deoxycarminomycin + CO2 ,
15-demethoxyaclacinomycin T + a reduced electron acceptor + H+ + oxygen = 10-decarboxymethylaclacinomycin T + CO2 + an oxidized electron acceptor + H2O ,
15-demethoxy-aclacinomycin A + a reduced electron acceptor + H+ + oxygen = 10-decarboxymethyl, 10-hydroxyaclacinomycin A + CO2 + an oxidized electron acceptor + H2O ,
15-demethoxy-ε-rhodomycinone + H+ → 15-decarboxymethyl-ε-rhodomycinone + CO2 ,
2-oxovalerate + H+ → butanal + CO2 ,
naphthalene + hydrogen carbonate = 2-naphthoate + H2O ,
3-carboxy-2-hydroxymuconate semialdehyde + H+ → (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + CO2 ,
3,6,8-trimethyl-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline → S-(+)-3,6,8-trimethylallantoin + CO2 + H+ ,
siroheme + 2 H+ → 12,18-didecarboxysiroheme + 2 CO2 ,
(-)-dehydrodiconiferyl acid carboxylate + H+ → 4,2'-dihydroxy-3,3'-dimethoxy-5'-(2''-carboxyvinyl)stilbene + CO2 ,
L-serine + H+ → ethanolamine + CO2 ,
2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate + H+ ↔ 2-hydroxy-6-oxo-7-methyl-octa-2,4-dienoate + CO2 ,
UDP-α-D-glucuronate + H+ → UDP-D-apiose + CO2 ,
ferulate + H+ ↔ 4-vinylguaiacol + CO2 ,
4-coumarate + H+ = 4-vinylphenol + CO2 ,
trans-cinnamate + H+ = styrene + CO2 ,
2-oxo-3-carboxy-4,5-cyclopropylhex-5-enoate + H+ → beta-methylenecyclopropyl pyruvate + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-octaprenyl)phenol + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-nonaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-nonaprenyl)phenol + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-heptaprenyl)phenol + CO2 ,
2-phosphoglycolate + 3-phospho-D-glycerate + 2 H+ ↔ D-ribulose-1,5-bisphosphate + oxygen ,
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H+ → 2-hexaprenyl-6-methoxyphenol + CO2

Enzymes and Genes:
ribulose-bisphosphate carboxylase : ATMG00280 ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase : cbbS , cbbL ( Synechocystis sp. PCC 6803 )
ribulose bisphosphate carboxylase/oxygenase : rbcS2B , ATCG00490 ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : rbcS3B , ATCG00490 ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : ATCG00490 , rbcS1A ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : rbcS1B , ATCG00490 ( Arabidopsis thaliana col )
phenolic acid decarboxylase : pad1 ( Bacillus subtilis )
ferulic acid decarboxylase : fdc1 ( Saccharomyces cerevisiae )
phenylacrylate decarboxylase : pad1 ( Saccharomyces cerevisiae )
UDP-D-xylose synthase / UDP-D-apiose synthase ( Petroselinum crispum )
UDP-D-apiose synthase / UDP-D-xylose synthase : AXS1 ( Arabidopsis thaliana col )
HCOMODA decarboxylase : cmtD ( Pseudomonas putida F1 )
serine decarboxylase ( Spinacia oleracea )
serine decarboxylase : AtSDC ( Arabidopsis thaliana col )
serine decarboxylase : BnSDC ( Brassica napus )
siroheme decarboxylase : ahbB , ahbA ( Desulfovibrio desulfuricans )
siroheme decarboxylase : nirH , nirG , nirD-L ( Paracoccus pantotrophus )
3-carboxy-2-hydroxymuconate semialdehyde decarboxylase : dhbB ( Pseudomonas reinekei )
pyruvate decarboxylase 3 : PDC6 ( Saccharomyces cerevisiae )
pyruvate decarboxylase 2 : PDC5 ( Saccharomyces cerevisiae )
pyruvate decarboxylase 1 : PDC1 ( Saccharomyces cerevisiae )
aclacinomycin 10-hydroxylase : rdmB ( Streptomyces purpurascens )
methylketone synthase 1 : MKS1 ( Lycopersicon hirsutum glabratum )
5-chloro-4-hydroxy-2-oxopentanoate decarboxylase (acylating) : salQ ( Salinispora tropica )
carboxyspermidine decarboxylase : C8J_1418 ( Campylobacter jejuni jejuni 81116 )
carboxynorspermidine decarboxylase : VVI_3048 ( Vibrio vulnificus CMCP6 )
carboxynorspermidine decarboxylase : nspC ( Vibrio alginolyticus NBRC 15630 = ATCC 17749 )
2-oxo-3-hexenedioate decarboxylase / 2-oxopent-5-chloro-3-enoate decarboxylase : cnbF ( Comamonas testosteroni CNB-1 )


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, biocyc14.