Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015
twitter

MetaCyc EC 4.1.1 -- Carboxy-lyases

Parent Class: EC-Numbers 4 -- Lyases 4.1 -- Carbon-carbon lyases

Instances:
4.1.1.1 -- pyruvate decarboxylase ,
4.1.1.2 -- oxalate decarboxylase ,
4.1.1.3 -- oxaloacetate decarboxylase ,
4.1.1.4 -- acetoacetate decarboxylase ,
4.1.1.5 -- acetolactate decarboxylase ,
4.1.1.6 -- aconitate decarboxylase ,
4.1.1.7 -- benzoylformate decarboxylase ,
4.1.1.8 -- oxalyl-CoA decarboxylase ,
4.1.1.9 -- malonyl-CoA decarboxylase ,
4.1.1.11 -- aspartate 1-decarboxylase ,
4.1.1.12 -- aspartate 4-decarboxylase ,
4.1.1.14 -- valine decarboxylase ,
4.1.1.15 -- glutamate decarboxylase ,
4.1.1.16 -- hydroxyglutamate decarboxylase ,
4.1.1.17 -- ornithine decarboxylase ,
4.1.1.18 -- lysine decarboxylase ,
4.1.1.19 -- arginine decarboxylase ,
4.1.1.20 -- diaminopimelate decarboxylase ,
4.1.1.21 -- phosphoribosylaminoimidazole carboxylase ,
4.1.1.22 -- histidine decarboxylase ,
4.1.1.23 -- orotidine-5′-phosphate decarboxylase ,
4.1.1.24 -- aminobenzoate decarboxylase ,
4.1.1.25 -- tyrosine decarboxylase ,
4.1.1.28 -- aromatic-L-amino-acid decarboxylase ,
4.1.1.29 -- sulfinoalanine decarboxylase ,
4.1.1.30 -- pantothenoylcysteine decarboxylase ,
4.1.1.31 -- phosphoenolpyruvate carboxylase ,
4.1.1.32 -- phosphoenolpyruvate carboxykinase (GTP) ,
4.1.1.33 -- diphosphomevalonate decarboxylase ,
4.1.1.34 -- dehydro-L-gulonate decarboxylase ,
4.1.1.35 -- UDP-glucuronate decarboxylase ,
4.1.1.36 -- phosphopantothenoylcysteine decarboxylase ,
4.1.1.37 -- uroporphyrinogen decarboxylase ,
4.1.1.38 -- phosphoenolpyruvate carboxykinase (diphosphate) ,
4.1.1.39 -- ribulose-bisphosphate carboxylase ,
4.1.1.40 -- hydroxypyruvate decarboxylase ,
4.1.1.41 -- methylmalonyl-CoA decarboxylase ,
4.1.1.42 -- carnitine decarboxylase ,
4.1.1.43 -- phenylpyruvate decarboxylase ,
4.1.1.44 -- 4-carboxymuconolactone decarboxylase ,
4.1.1.45 -- aminocarboxymuconate-semialdehyde decarboxylase ,
4.1.1.46 -- o-pyrocatechuate decarboxylase ,
4.1.1.47 -- tartronate-semialdehyde synthase ,
4.1.1.48 -- indole-3-glycerol-phosphate synthase ,
4.1.1.49 -- phosphoenolpyruvate carboxykinase (ATP) ,
4.1.1.50 -- adenosylmethionine decarboxylase ,
4.1.1.51 -- 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase ,
4.1.1.52 -- 6-methylsalicylate decarboxylase ,
4.1.1.53 -- phenylalanine decarboxylase ,
4.1.1.54 -- dihydroxyfumarate decarboxylase ,
4.1.1.55 -- 4,5-dihydroxyphthalate decarboxylase ,
4.1.1.56 -- 3-oxolaurate decarboxylase ,
4.1.1.57 -- methionine decarboxylase ,
4.1.1.58 -- orsellinate decarboxylase ,
4.1.1.59 -- gallate decarboxylase ,
4.1.1.60 -- stipitatonate decarboxylase ,
4.1.1.61 -- 4-hydroxybenzoate decarboxylase ,
4.1.1.62 -- gentisate decarboxylase ,
4.1.1.63 -- protocatechuate decarboxylase ,
4.1.1.64 -- 2,2-dialkylglycine decarboxylase (pyruvate) ,
4.1.1.65 -- phosphatidylserine decarboxylase ,
4.1.1.66 -- uracil-5-carboxylate decarboxylase ,
4.1.1.67 -- UDP-galacturonate decarboxylase ,
4.1.1.68 -- 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase ,
4.1.1.69 -- 3,4-dihydroxyphthalate decarboxylase ,
4.1.1.70 -- glutaconyl-CoA decarboxylase ,
4.1.1.71 -- 2-oxoglutarate decarboxylase ,
4.1.1.72 -- branched-chain-2-oxoacid decarboxylase ,
4.1.1.73 -- tartrate decarboxylase ,
4.1.1.74 -- indolepyruvate decarboxylase ,
4.1.1.75 -- 5-guanidino-2-oxopentanoate decarboxylase ,
4.1.1.76 -- arylmalonate decarboxylase ,
4.1.1.77 -- 2-oxo-3-hexenedioate decarboxylase ,
4.1.1.78 -- acetylenedicarboxylate decarboxylase ,
4.1.1.79 -- sulfopyruvate decarboxylase ,
4.1.1.80 -- 4-hydroxyphenylpyruvate decarboxylase ,
4.1.1.81 -- threonine-phosphate decarboxylase ,
4.1.1.82 -- phosphonopyruvate decarboxylase ,
4.1.1.83 -- 4-hydroxyphenylacetate decarboxylase ,
4.1.1.84 -- D-dopachrome decarboxylase ,
4.1.1.85 -- 3-dehydro-L-gulonate-6-phosphate decarboxylase ,
4.1.1.86 -- diaminobutyrate decarboxylase ,
4.1.1.87 -- malonyl-S-ACP decarboxylase ,
4.1.1.88 -- biotin-independent malonate decarboxylase ,
4.1.1.89 -- biotin-dependent malonate decarboxylase ,
4.1.1.90 -- peptidyl-glutamate 4-carboxylase ,
4.1.1.91 -- salicylate decarboxylase ,
4.1.1.92 -- indole-3-carboxylate decarboxylase ,
4.1.1.93 -- pyrrole-2-carboxylate decarboxylase ,
4.1.1.94 -- ethylmalonyl-CoA decarboxylase ,
4.1.1.95 -- L-glutamyl-[BtrI acyl-carrier protein] decarboxylase ,
4.1.1.96 -- carboxynorspermidine decarboxylase ,
4.1.1.97 -- 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase ,
4.1.1.98 -- 4-hydroxy-3-polyprenylbenzoate decarboxylase ,
4.1.1.99 -- phosphomevalonate decarboxylase

Unofficial Reactions:
2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate + H+ ↔ 2-hydroxy-6-oxo-7-methyl-octa-2,4-dienoate + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-nonaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-nonaprenyl)phenol + CO2 ,
15-demethoxy-ε-rhodomycinone + H+ → 15-decarboxymethyl-ε-rhodomycinone + CO2 ,
3-phosphonomethylmalate + an oxidized unknown electron acceptor + H+ → 2-oxo-4-phosphonobutanoate + CO2 + an reduced unknown electron acceptor ,
10-carboxy-3-deoxycarminomycin + H+ → 13-deoxycarminomycin + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-heptaprenyl)phenol + CO2 ,
γ-L-glutamyl-(S)-2-carboxypropyl-L-cysteinyl-glycine + an oxidized unknown electron acceptor + H+ → γ-L-glutamyl-(S)-allyl-L-cysteinyl-glycine + CO2 + an reduced unknown electron acceptor ,
2-oxovalerate + H+ → butanal + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 ,
a 3-oxoacid + H+ → a methyl ketone + CO2 ,
3-carboxy-2-hydroxymuconate semialdehyde + H+ → (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + CO2 ,
15-demethoxy-aclacinomycin A + an reduced unknown electron acceptor + H+ + oxygen → 10-decarboxymethyl, 10-hydroxyaclacinomycin A + CO2 + an oxidized unknown electron acceptor + H2O ,
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H+ → 2-hexaprenyl-6-methoxyphenol + CO2 ,
2-phosphoglycolate + 3-phospho-D-glycerate + 2 H+ → D-ribulose-1,5-bisphosphate + oxygen ,
cytosyl-β-D-glucuronate + 2 S-adenosyl-L-methionine + 2 a reduced flavodoxin = cytosyl-α-L-arabinopyranose + CO2 + 2 5'-deoxyadenosine + 2 L-methionine + 2 an oxidized flavodoxin + H+ ,
L-serine + H+ → ethanolamine + CO2 ,
2-oxopent-5-chloro-3-enoate + H+ → 2-oxo-5-chloro-4-pentenoate + CO2 ,
trans-cinnamate + H+ = styrene + CO2 ,
ferulate + H+ = 4-vinylguaiacol + CO2 ,
2-oxo-3-carboxy-4,5-cyclopropylhex-5-enoate + H+ → beta-methylenecyclopropyl pyruvate + CO2 ,
naphthalene + hydrogen carbonate → 2-naphthoate + H2O ,
carboxyspermidine + H+ → spermidine + CO2 ,
3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H+ → 2-methoxy-6-(all-trans-octaprenyl)phenol + CO2 ,
3-hexaprenyl-4-amino-5-methoxybenzoate + H+ → 2-hexaprenyl-6-methoxyaminobenzene + CO2 ,
siroheme + 2 H+ → 12,18-didecarboxysiroheme + 2 CO2 ,
5-chloro-4-hydroxy-2-oxopentanoate + 2 an oxidized ferredoxin + coenzyme A → 4-chloro-3-hydroxybutyryl-CoA + CO2 + 2 a reduced ferredoxin + H+ ,
4-coumarate + H+ = 4-vinylphenol + CO2 ,
15-demethoxyaclacinomycin T + an reduced unknown electron acceptor + H+ + oxygen → 10-decarboxymethylaclacinomycin T + CO2 + an oxidized unknown electron acceptor + H2O ,
5-carboxyvanillate + H+ → vanillate + CO2 ,
(-)-dehydrodiconiferyl acid carboxylate + H+ → 4,2'-dihydroxy-3,3'-dimethoxy-5'-(2''-carboxyvinyl)stilbene + CO2 ,
UDP-α-D-glucuronate + H+ → UDP-D-apiose + CO2 ,
3,6,8-trimethyl-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + an oxidized unknown electron acceptor + H+S-(+)-3,6,8-trimethylallantoin + CO2 + an reduced unknown electron acceptor

Enzymes and Genes:
UDP-D-xylose synthase / UDP-D-apiose synthase ( Petroselinum crispum )
UDP-D-apiose synthase / UDP-D-xylose synthase : AXS1 ( Arabidopsis thaliana col )
5-carboxyvanillate decarboxylase : ligW2 ( Sphingomonas sp. SYK6 )
5-carboxyvanillate decarboxylase : ligW ( Sphingomonas sp. SYK6 )
5-chloro-4-hydroxy-2-oxopentanoate decarboxylase (acylating) : salQ ( Salinispora tropica )
siroheme decarboxylase : ahbB , ahbA ( Desulfovibrio desulfuricans )
siroheme decarboxylase : nirH , nirG , nirD-L ( Paracoccus pantotrophus )
carboxyspermidine decarboxylase : C8J_1418 ( Campylobacter jejuni jejuni 81116 )
carboxynorspermidine decarboxylase : VVI_3048 ( Vibrio vulnificus CMCP6 )
carboxynorspermidine decarboxylase : nspC ( Vibrio alginolyticus NBRC 15630 = ATCC 17749 )
naphthalene carboxylase : N47_K27500 , N47_K27540 ( delta proteobacterium N47 )
phenacrylic acid acid decarboxylase : fdc1 ( Saccharomyces cerevisiae )
2-oxo-3-hexenedioate decarboxylase / 2-oxopent-5-chloro-3-enoate decarboxylase : cnbF ( Comamonas testosteroni CNB-1 )
serine decarboxylase ( Spinacia oleracea )
serine decarboxylase : AtSDC ( Arabidopsis thaliana col )
serine decarboxylase : BnSDC ( Brassica napus )
cytosinine synthase : blsE ( Streptomyces griseochromogenes )
ribulose bisphosphate carboxylase : cbbS , cbbL ( Synechocystis sp. PCC 6803 )
ribulose bisphosphate carboxylase/oxygenase : RBCS-2B , RBCL ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : RBCS-3B , RBCL ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : RBCL , RBCS-1A ( Arabidopsis thaliana col )
ribulose bisphosphate carboxylase/oxygenase : RBSS-1B , RBCL ( Arabidopsis thaliana col )
aclacinomycin 10-hydroxylase : rdmB ( Streptomyces purpurascens )
3-carboxy-2-hydroxymuconate semialdehyde decarboxylase : dhbB ( Pseudomonas reinekei )
methylketone synthase 1 : MKS1 ( Lycopersicon hirsutum glabratum )
pyruvate decarboxylase 3 : PDC6 ( Saccharomyces cerevisiae )
pyruvate decarboxylase 2 : PDC5 ( Saccharomyces cerevisiae )
pyruvate decarboxylase 1 : PDC1 ( Saccharomyces cerevisiae )
HCOMODA decarboxylase : cmtD ( Pseudomonas putida F1 )


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Aug 30, 2015, biocyc14.