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MetaCyc EC 4.1.2 -- Aldehyde-lyases

Parent Class: EC-Numbers4 -- Lyases4.1 -- Carbon-carbon lyases

Instances:
4.1.2.2 -- ketotetrose-phosphate aldolase,
4.1.2.4 -- deoxyribose-phosphate aldolase,
4.1.2.5 -- L-threonine aldolase,
4.1.2.8 -- indole-3-glycerol-phosphate lyase,
4.1.2.9 -- phosphoketolase,
4.1.2.10 -- (R)-mandelonitrile lyase,
4.1.2.11 -- hydroxymandelonitrile lyase,
4.1.2.12 -- 2-dehydropantoate aldolase,
4.1.2.13 -- fructose-bisphosphate aldolase,
4.1.2.14 -- 2-dehydro-3-deoxy-phosphogluconate aldolase,
4.1.2.17 -- L-fuculose-phosphate aldolase,
4.1.2.18 -- 2-dehydro-3-deoxy-L-pentonate aldolase,
4.1.2.19 -- rhamnulose-1-phosphate aldolase,
4.1.2.20 -- 2-dehydro-3-deoxyglucarate aldolase,
4.1.2.21 -- 2-dehydro-3-deoxy-6-phosphogalactonate aldolase,
4.1.2.22 -- fructose-6-phosphate phosphoketolase,
4.1.2.23 -- 3-deoxy-D-manno-octulosonate aldolase,
4.1.2.24 -- dimethylaniline-N-oxide aldolase,
4.1.2.25 -- dihydroneopterin aldolase,
4.1.2.26 -- phenylserine aldolase,
4.1.2.27 -- sphinganine-1-phosphate aldolase,
4.1.2.28 -- 2-dehydro-3-deoxy-D-pentonate aldolase,
4.1.2.29 -- 5-dehydro-2-deoxyphosphogluconate aldolase,
4.1.2.30 -- 17α-hydroxyprogesterone aldolase,
4.1.2.32 -- trimethylamine-oxide aldolase,
4.1.2.33 -- fucosterol-epoxide lyase,
4.1.2.34 -- 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase,
4.1.2.35 -- propioin synthase,
4.1.2.36 -- lactate aldolase,
4.1.2.38 -- benzoin aldolase,
4.1.2.40 -- tagatose-bisphosphate aldolase,
4.1.2.41 -- vanillin synthase,
4.1.2.42 -- D-threonine aldolase,
4.1.2.43 -- 3-hexulose-6-phosphate synthase,
4.1.2.44 -- benzoyl-CoA-dihydrodiol lyase,
4.1.2.45 -- trans-o-hydroxybenzylidenepyruvate hydratase-aldolase,
4.1.2.46 -- aliphatic (R)-hydroxynitrile lyase,
4.1.2.47 -- (S)-hydroxynitrile lyase,
4.1.2.48 -- low-specificity L-threonine aldolase,
4.1.2.49 -- L-allo-threonine aldolase,
4.1.2.50 -- 6-carboxytetrahydropterin synthase,
4.1.2.51 -- 2-dehydro-3-deoxy-D-gluconate aldolase ,
4.1.2.52 -- 4-hydroxy-2-oxoheptanedioate aldolase,
4.1.2.53 -- 2-keto-3-deoxy-L-rhamnonate aldolase,
4.1.2.54 -- L-threo-3-deoxy-hexylosonate aldolase,
4.1.2.55 -- 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase ,
4.1.2.56 -- 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase,
4.1.2.57 -- sulfofructosephosphate aldolase,
4.1.2.p -- 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase

Unofficial Reactions:
triethylamine N-oxide + H+ → diethylamine + acetaldehyde,
DL-allothreonine ↔ acetaldehyde + glycine,
glycerone phosphate + D-erythrose 4-phosphate ↔ D-sedoheptulose-1,7-bisphosphate,
2,4-dihydroxyhept-2-enedioate = succinate semialdehyde + pyruvate,
2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA,
4S-hydroperoxy,17S-hydroxy-docosahexaenoate → 4(5)-epoxy-17S-hydroxy-docosahexaenoate + H2O,
2-hydroxyphytanoyl-CoA → pristanal + formyl-CoA,
diethylamine N-oxide + H+ → ethylamine + acetaldehyde,
4-hydroxy-L-threonine ↔ glycolaldehyde + glycine,
β-D-fructofuranose 6-phosphate ↔ dihydroxyacetone + D-glyceraldehyde 3-phosphate,
3-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA → 4-hydroxybenzaldehyde + acetyl-CoA

Enzymes and Genes:
4-coumaroyl-CoA hydratase/aldolase: couA ( Rhodopseudomonas palustris CGA009 )
fructose 6-phosphate aldolase 1: fsaA ( Escherichia coli K-12 substr. MG1655 )
fructose 6-phosphate aldolase 2: fsaB ( Escherichia coli K-12 substr. MG1655 )
low-specificity L-threonine aldolase: ltaE ( Escherichia coli K-12 substr. MG1655 )
2-hydroxyacyl-CoA lyase 1: HACL1 ( Homo sapiens )
2-hydroxyacyl-CoA lyase 1: Hacl1 ( Rattus norvegicus )
fructose bisphosphate aldolase class II: fbaA ( Escherichia coli K-12 substr. MG1655 )
cytosolic fructose-1,6-bisphosphate aldolase ( Vigna radiata radiata )
fructose-bisphosphate aldolase / sedoheptulose-1,7-bisphosphate aldolase: fbaB ( Synechocystis sp. PCC 6803 )
fructose-bisphosphate aldolase / sedoheptulose-1,7-bisphosphate aldolase: fbaA ( Synechocystis sp. PCC 6803 )
serine hydroxymethyltransferase: glyA ( Escherichia coli K-12 substr. MG1655 )


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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