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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc EC 6.2.1 -- Acid--thiol ligases

Parent Class: EC-Numbers 6 -- Ligases 6.2 -- Forming carbon-sulfur bonds

Instances:
6.2.1.1 -- acetate—CoA ligase ,
6.2.1.2 -- butyrate—CoA ligase ,
6.2.1.3 -- long-chain-fatty-acid—CoA ligase ,
6.2.1.4 -- succinate—CoA ligase (GDP-forming) ,
6.2.1.5 -- succinate—CoA ligase (ADP-forming) ,
6.2.1.6 -- glutarate—CoA ligase ,
6.2.1.7 -- cholate—CoA ligase ,
6.2.1.8 -- oxalate—CoA ligase ,
6.2.1.9 -- malate—CoA ligase ,
6.2.1.10 -- carboxylic acid—CoA ligase (GDP-forming) ,
6.2.1.11 -- biotin—CoA ligase ,
6.2.1.12 -- 4-coumarate—CoA ligase ,
6.2.1.13 -- acetate—CoA ligase (ADP-forming) ,
6.2.1.14 -- 6-carboxyhexanoate—CoA ligase ,
6.2.1.15 -- arachidonate—CoA ligase ,
6.2.1.16 -- acetoacetate—CoA ligase ,
6.2.1.17 -- propionate—CoA ligase ,
6.2.1.18 -- citrate—CoA ligase ,
6.2.1.19 -- long-chain-fatty-acid—luciferin-component ligase ,
6.2.1.20 -- long-chain-fatty-acid—[acyl-carrier-protein] ligase ,
6.2.1.22 -- [citrate (pro-3S)-lyase] ligase ,
6.2.1.23 -- dicarboxylate—CoA ligase ,
6.2.1.24 -- phytanate—CoA ligase ,
6.2.1.25 -- benzoate—CoA ligase ,
6.2.1.26 -- o-succinylbenzoate—CoA ligase ,
6.2.1.27 -- 4-hydroxybenzoate—CoA ligase ,
6.2.1.28 -- 3α,7α-dihydroxy-5β-cholestanate—CoA ligase ,
6.2.1.30 -- phenylacetate—CoA ligase ,
6.2.1.31 -- 2-furoate—CoA ligase ,
6.2.1.32 -- anthranilate—CoA ligase ,
6.2.1.33 -- 4-chlorobenzoate—CoA ligase ,
6.2.1.34 -- trans-feruloyl-CoA synthase ,
6.2.1.35 -- ACP-SH:acetate ligase ,
6.2.1.36 -- 3-hydroxypropionyl-CoA synthase ,
6.2.1.37 -- 3-hydroxybenzoate—CoA ligase ,
6.2.1.38 -- (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase ,
6.2.1.39 -- [butirosin acyl-carrier protein]—L-glutamate ligase ,
6.2.1.40 -- 4-hydroxybutyrate—CoA ligase ,
6.2.1.41 -- 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate—CoA ligase ,
6.2.1.43 -- 2-hydroxy-7-methoxy-5-methyl-1-naphthoate—CoA ligase ,
6.2.1.f -- 3-oxocholest-4-en-26-oate–CoA ligase ,
6.2.1.i -- ubiquitin-activating enzyme E1

Unofficial Reactions:
L-carnitine + ATP + coenzyme A → L-carnitinyl-CoA + AMP + diphosphate ,
cyclohexane-1-carboxylate + ATP + coenzyme A + H2O → cyclohexane-1-carbonyl-CoA + AMP + 2 phosphate + H+ ,
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoate + ATP + coenzyme A → OPC8-CoA + AMP + diphosphate ,
sulfoacetate + ATP + coenzyme A → sulfoacetyl-CoA + AMP + diphosphate ,
citronellate + ATP + coenzyme A → citronellyll-CoA + AMP + diphosphate ,
an in-chain hydroxy fatty acid + ATP + coenzyme A → a hydroxyacyl-CoA + AMP + diphosphate ,
an ω-hydroxy fatty acid + ATP + coenzyme A → a hydroxyacyl-CoA + AMP + diphosphate ,
malonate + ATP + coenzyme A → malonyl-CoA + AMP + diphosphate ,
3,24-dioxo-cholest-4-en-26-oate + ATP + coenzyme A → 3,24-dioxocholest-4-en-26-oyl-CoA + AMP + diphosphate ,
3-oxo-24-ethyl-cholest-4-en-26-oate + ATP + coenzyme A → 3-oxo-24-ethyl-cholest-4-en-26-oyl-CoA + AMP + diphosphate ,
2-furoate + ATP + coenzyme A → 2-furoyl-CoA + ADP + phosphate ,
L-β-phenylalanine + ATP + coenzyme A → (3R)-3-amino-3-phenylpropanoyl-CoA + AMP + diphosphate ,
hexanoate + ATP + coenzyme A → hexanoyl-CoA + AMP + diphosphate ,
2-naphthoate + ATP + coenzyme A → 2-naphthoyl-CoA + AMP + diphosphate ,
3-sulfinopropionate + ATP + coenzyme A → 3-sulfinopropanoyl-CoA + ADP + phosphate ,
5-aminolevulinate + ATP + coenzyme A → 5-aminolevulinyl-CoA + AMP + diphosphate ,
trans-cinnamate + ATP + coenzyme A → (E)-cinnamoyl-CoA + AMP + diphosphate ,
N-methylanthranilate + ATP + coenzyme A → N-methylanthraniloyl-CoA + AMP + diphosphate ,
a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
malonate + a holo-[acyl-carrier protein] + ATP → a malonyl-[acp] + AMP + diphosphate ,
an HmqF protein + decanoate + ATP → a decanoyl-HmqF protein + AMP + diphosphate ,
L-proline + [PigG peptidyl-carrier protein] + ATP → L-prolyl-S-[PigG peptidyl-carrier protein] + AMP + diphosphate ,
a C52-α-meroacyl-[acp] + ATP + H2O → a C52-α-meroacyl-adenylate + a holo-[acyl-carrier protein] + diphosphate ,
a cis-methoxy-C59-meroacyl-[acp] + ATP + H2O → a cis-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein] + diphosphate ,
a trans-methoxy-C60-meroacyl-[acp] + ATP + H2O → a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein] + diphosphate ,
a cis-keto-C60-meroacyl-[acp] + ATP + H2O → a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein] + diphosphate ,
a trans-keto-C61-meroacyl-[acp] + ATP + H2O → a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein] + diphosphate

Enzymes and Genes:
acyl-CoA synthetase : fadD32 ( Mycobacterium tuberculosis H37Rv )
L-proline--[PigG acyl-carrier protein] ligase : pigI ( Serratia marcescens )
decanoyl-[acp] 2-dehydrogenase : hmqF ( Burkholderia thailandensis E264 )
malonyl-ACP synthetase ( Pisum sativum )
cinnamate:CoA ligase : CNL ( Hypericum calycinum )
cinnamate:CoA ligase : CNL ( Petunia x hybrida )
cinnamate:CoA ligase : encH ( Streptomyces maritimus )
cinnamate:CoA ligase ( Hypericum androsaemum )
acyl-CoA ligase : ORF35 ( Streptomyces aizunenesis NRRL-B-11277 )
succinyl-CoA synthetase : sucD , sucC ( Advenella mimigardefordensis DPN7 )
hexanoyl-CoA synthetase : AAE1 ( Cannabis sativa )
acyl-CoA synthetase : alkK ( Pseudomonas oleovorans )
acyl-CoA synthetase : LACS6 ( Arabidopsis thaliana col )
acyl-CoA synthetase : LACS7 ( Arabidopsis thaliana col )
long-chain-fatty-acid--CoA ligase 1 : ACSL1 ( Homo sapiens )
very long-chain acyl-CoA synthetase : SLC27A2 ( Homo sapiens )
Long-chain-fatty-acid--CoA ligase ACSBG2 : ACSBG2 ( Homo sapiens )
Long-chain-fatty-acid--CoA ligase ACSBG1 : ACSBG1 ( Homo sapiens )
fatty-acid-Coenzyme A ligase, long-chain 6 : FACL6 ( Homo sapiens )
Long-chain-fatty-acid--CoA ligase 4 : ACSL4 ( Homo sapiens )
Long-chain-fatty-acid--CoA ligase 5 : ACSL5 ( Homo sapiens )
Long-chain-fatty-acid--CoA ligase 6 : ACSL6 ( Homo sapiens )
Long-chain-fatty-acid--CoA ligase 3 : ACSL3 ( Homo sapiens )
acyl-CoA synthetase : FAA2 ( Saccharomyces cerevisiae )
short chain acyl-CoA synthetase : fadK ( Escherichia coli K-12 substr. MG1655 )
fatty acyl-CoA synthetase : fadD ( Escherichia coli K-12 substr. MG1655 )
furoyl-CoA synthetase : hmfD ( Cupriavidus basilensis )
malonate-CoA synthetase ( Pisum sativum )
fatty acyl-CoA synthetase : ACOS5 ( Arabidopsis thaliana col )
sulfoacetate-CoA ligase (AMP-forming) : SauT ( Ralstonia eutropha H16 )
3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase : OPCL1 ( Arabidopsis thaliana col )
cyclohexanecarboxylate-CoA ligase : aliA ( Rhodopseudomonas palustris )
carnitine-CoA ligase : caiC ( Escherichia coli K-12 substr. MG1655 )


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 21, 2014, biocyc13.