Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Compound Class: S0

Synonyms: elemental sulfur, orthorhombic sulfur, rhombic sulfur

Superclasses: an inorganic compound

Summary:
Elemental sulfur appears in a number of different allotropic modifications: rhombic, monoclinic, polymeric, and others. The rhombic structure is the most common. Both the rhombic and monoclinic forms of sulfur are made up of eight sulfur atoms arranged in a puckered-ring structure. At one atmosphere pressure and temperatures less than 95.4C, rhombic is the stable crystalline form. Above 95.4 C to the melt temperature of 118.9 C, the monoclinic crystalline structure is dominant [Steudel00].

In addition, elemental sulfur always contains some polymeric sulfur consisting of chain-like macromolecules. The S-S bond energy is lower in polymeric sulfur than in ring sulfur [Franz07].

Monoisotopic Molecular Weight: 31.97207069 Daltons

SMILES: S

InChI: InChI=1/H2S/h1H2/p-1/fHS/h1h/q-1

Unification Links: ChEBI:17909 , KEGG:C00087

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): 8.770001 Inferred by computational analysis [Latendresse13]

Reactions known to consume the compound:

sulfur disproportionation I (anaerobic) :
2 S0 + 3 H2O → sulfite + hydrogen sulfide + 4 H+

sulfur disproportionation II (aerobic) :
5 S0 + oxygen + 4 H2O → sulfite + thiosulfate + 2 hydrogen sulfide + 3 H+

sulfur oxidation I (aerobic) , sulfur oxidation II (Fe+3-dependent) :
glutathione + S0 → S-sulfanylglutathione

sulfur reduction I :
S0 + H2 → hydrogen sulfide

sulfur reduction II (via polysulfide) :
n S0 + HS- → (sulfide)n+1 + H+

Not in pathways:
hydrogen sulfide + NAD(P)+S0 + NAD(P)H + H+
S0 + oxygen + H2O → sulfite + 2 H+
4 S0 + 4 H2O + oxygen → 2 hydrogen sulfide + 2 sulfite + 4 H+

Reactions known to produce the compound:

glucosinolate breakdown (via thiocyanate-forming protein) :
benzylglucosinolate aglycone → phenylacetonitrile + sulfate + S0

sulfide oxidation II (sulfide dehydrogenase) :
hydrogen sulfide + 2 an oxidized c-type cytochrome → S0 + 2 a reduced c-type cytochrome + 2 H+

tetrathionate oxidation :
tetrathionate + H2O → thiosulfate + S0 + sulfate + H+

tetrathionate reductiuon II (to trithionate) :
tetrathionate → S0 + trithionate

In Reactions of unknown directionality:

Not in pathways:
a sulfur-binding protein + S0 = a sulfurylated sulfur-binding protein

Enzymes inhibited by S0, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: sulfide dehydrogenase [Quentmeier04]


References

Franz07: Franz B, Lichtenberg H, Hormes J, Modrow H, Dahl C, Prange A (2007). "Utilization of solid "elemental" sulfur by the phototrophic purple sulfur bacterium Allochromatium vinosum: a sulfur K-edge X-ray absorption spectroscopy study." Microbiology 153(Pt 4);1268-74. PMID: 17379736

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Quentmeier04: Quentmeier A, Hellwig P, Bardischewsky F, Wichmann R, Friedrich CG (2004). "Sulfide dehydrogenase activity of the monomeric flavoprotein SoxF of Paracoccus pantotrophus." Biochemistry 43(46);14696-703. PMID: 15544340

Steudel00: Steudel, R. (2000). "The chemical sulfur cycle." Environmental Technologies to Treat Sulfur Pollution, pp. 1-31. Edited by P. N. L. Lens & L. Hulshof Pol. London: IWA Publishing.


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 21, 2014, BIOCYC14A.