Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Gene-Ontology-Terms Class: GO:0004519 - endonuclease activity

Definition: Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

Parent Classes:
GO:0004518 - nuclease activity

Child Classes:
GO:0004520 - endodeoxyribonuclease activity (16) ,
GO:0004521 - endoribonuclease activity (19) ,
GO:0016893 - endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (11) ,
GO:0016894 - endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters (3) ,
GO:0043765 - T/G mismatch-specific endonuclease activity (1)

Term Members:
30S ribosomal subunit protein S16 (rpsP) ,
MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity (chpA) ,
RNase P protein component; processes tRNA, 4.5S RNA (rnpA) ,
ribonuclease G (RNAse G) monomer (rng) ,
restriction of DNA at 5-methylcytosine residues (mcrA) ,
host restriction; endonuclease R (hsdR) ,
MutH ,
RNase HI, degrades RNA of DNA-RNA hybrids, participates in DNA replication (rnhA) ,
RNAse HII, degrades RNA of DNA-RNA hybrids (rnhB) ,
exonuclease III (xthA) ,
mRNA interferase, toxin of the MqsR-MqsA toxin-antitoxin system ,
CP4-57 prophage; RNase LS, toxin of the RnlAB toxin-antitoxin system ,
ribosome-dependent mRNA interferase, toxin of the YafO-YafN toxin-antitoxin system ,
translation-dependent mRNA interferase, toxin of the HigB-HigA toxin-antitoxin system ,
toxin of the YafQ-DinJ toxin-antitoxin system ,
Qin prophage; toxin of the RelE-RelB toxin-antitoxin system and cofactor to enhance the repressor activity of RelB ,
MrcB subunit of 5-methylcytosine restriction system (mcrB) ,
endonuclease IV (nfo) ,
formamidopyrimidine DNA glycosylase (mutM) ,
Rbn ,
crRNA endonuclease (casE) ,
YhaV toxic endonuclease ,
toxin of the YoeB-YefM toxin-antitoxin pair ,
RNase III (rnc) ,
ChpB toxin of the ChpB-ChpS toxin-antitoxin system ,
DNA-specific endonuclease I (endA) ,
RecBCD ,
RecB ,
RecC ,
RecD ,
endonuclease V (deoxyinosine 3'-endonuclease) (nfi) ,
RNase I, cleaves phosphodiester bond between any two nucleotides ,
RNase E (rne)

Unification Links: GO:0004519


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC13A.