MetaCyc Gene-Ontology-Terms Class: GO:0006084 - acetyl-CoA metabolic process

Synonyms: acetyl coenzyme A metabolic process, acetyl coenzyme A metabolism, acetyl-CoA metabolism

Definition: The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.

Parent Classes:
GO:0006637 - acyl-CoA metabolic process

Child Classes:
GO:0006085 - acetyl-CoA biosynthetic process (5) ,
GO:0019474 - L-lysine catabolic process to acetyl-CoA (1)

Term Members:
propionyl-CoA:succinate CoA transferase (scpC) ,
citrate lyase, citryl-ACP lyase β subunit (citE) ,
citrate lyase, citrate-ACP transferase α subunit (citF) ,
pyruvate dehydrogenase E1 component α subunit (somatic) (PDHA1)

Unification Links: GO:0006084

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri Oct 9, 2015, biocyc13.