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MetaCyc Gene-Ontology-Terms Class: GO:0006412 - translation

Synonyms: GO:0006416, GO:0006453, GO:0043037, protein anabolism, protein biosynthesis, protein biosynthetic process, protein formation, protein synthesis, protein translation

Definition: The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.

Parent Classes:
GO:0044267 - cellular protein metabolic process ,
GO:0034645 - cellular macromolecule biosynthetic process

Part Of:
GO:0010467 - gene expression

Parts:
GO:1990145 - maintenance of translational fidelity (2) ,
GO:0006417 - regulation of translation (28)

Term Members:
50S ribosomal subunit protein L16 (rplP) ,
50S ribosomal subunit protein L11 (rplK) ,
30S ribosomal subunit protein S21 (rpsU) ,
30S ribosomal subunit protein S5 (rpsE) ,
50S ribosomal subunit protein L22 (rplV) ,
50S ribosomal subunit protein L1 (rplA) ,
30S ribosomal subunit protein S18 (rpsR) ,
30S ribosomal subunit protein S2 (rpsB) ,
50S ribosomal subunit protein L18 (rplR) ,
50S ribosomal subunit protein L21 (rplU) ,
50S ribosomal subunit protein L35 (rpmI) ,
30S ribosomal subunit protein S15 (rpsO) ,
50S ribosomal subunit protein L34 (rpmH) ,
50S ribosomal subunit protein L14 (rplN) ,
30S ribosomal subunit protein S12 (rpsL) ,
50S ribosomal subunit protein L31 (rpmE) ,
50S ribosomal subunit protein L10 (rplJ) ,
30S ribosomal subunit protein S9 (rpsI) ,
50S ribosomal subunit protein L28 (rpmB) ,
50S ribosomal subunit protein L5 (rplE) ,
30S ribosomal subunit protein S6 (rpsF) ,
50S ribosomal subunit protein L23 (rplW) ,
50S ribosomal subunit protein L2 (rplB) ,
30S ribosomal subunit protein S19 (rpsS) ,
30S ribosomal subunit protein S3 (rpsC) ,
50S ribosomal subunit protein L19 (rplS) ,
50S ribosomal subunit protein L27 (rpmA) ,
50S ribosomal subunit protein L36 (rpmJ) ,
30S ribosomal subunit protein S16 (rpsP) ,
50S ribosomal subunit protein L15 (rplO) ,
protein chain elongation factor EF-P (efp) ,
30S ribosomal subunit protein S13 (rpsM) ,
50S ribosomal subunit protein L32 (rpmF) ,
50S ribosomal subunit protein L12 (rplL) ,
30S ribosomal subunit protein S10 (rpsJ) ,
50S ribosomal subunit protein L29 (rpmC) ,
50S ribosomal subunit protein L6 (rplF) ,
30S ribosomal subunit protein S7 (rpsG) ,
50S ribosomal subunit protein L24 (rplX) ,
50S ribosomal subunit protein L3 (rplC) ,
30S ribosomal subunit protein S20 (rpsT) ,
30S ribosomal subunit protein S4 (rpsD) ,
50S ribosomal subunit protein L20 (rplT) ,
30S ribosomal subunit protein S17 (rpsQ) ,
30S ribosomal subunit protein S1 (rpsA) ,
50S ribosomal subunit protein L17 (rplQ) ,
30S ribosomal subunit protein S14 (rpsN) ,
50S ribosomal subunit protein L33 (rpmG) ,
50S ribosomal subunit protein L13 (rplM) ,
30S ribosomal subunit protein S11 (rpsK) ,
50S ribosomal subunit protein L30 (rpmD) ,
50S ribosomal subunit protein L9 (rplI) ,
30S ribosomal subunit protein S22 (sra) ,
30S ribosomal subunit protein S8 (rpsH) ,
50S ribosomal subunit protein L25 (rplY) ,
50S ribosomal subunit protein L4 (rplD) ,
selenocysteine synthase (selA) ,
adenylate kinase (adk) ,
glutamyl-tRNA synthetase (gltX) ,
arginyl-tRNA synthetase (argS) ,
cysteinyl-tRNA synthetase (cysS) ,
glutaminyl-tRNA synthetase (glnS) ,
isoleucyl-tRNA synthetase (ileS) ,
leucyl-tRNA synthetase (leuS) ,
valyl-tRNA synthetase (valS) ,
alanyl-tRNA synthetase (alaS) ,
asparaginyl-tRNA synthetase (asnS) ,
aspartyl-tRNA synthetase (aspS) ,
tyrosyl-tRNA synthetase (tyrS) ,
tryptophanyl-tRNA synthetase (trpS) ,
threonyl-tRNA synthetase (thrS) ,
seryl-tRNA synthetase (serS) ,
prolyl-tRNA synthetase (proS) ,
phenylalanyl-tRNA synthetase β-chain (pheT) ,
phenylalanyl-tRNA synthetase α-chain (pheS) ,
lysyl tRNA synthetase (LysRSs), constitutive (lysS) ,
histidyl-tRNA synthetase (hisS) ,
glycyl-tRNA synthetase, α subunit (glyQ) ,
glycyl-tRNA synthetase, β subunit (glyS) ,
methionyl-tRNA synthetase (metG) ,
selenocysteyl-tRNA-specific translation elongation factor (selB) ,
peptide deformylase ,
10-formyltetrahydrofolate:L-methionyl-tRNAfMet N-formyltransferase (fmt) ,
peptidyl-tRNA hydrolase (pth) ,
ribosomal protein S6 modification protein (rimK) ,
lysyl-tRNA synthetase (lysU) ,
RING-type E3 ubiquitin transferase UBR1 ,
Hydroxyindole O-methyltransferase (ASMT) ,
5S ribosomal RNA (rrfA) ,
23S ribosomal RNA (rrlA) ,
16S ribosomal RNA (rrsA)

Unification Links: GO:0006412


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Jul 5, 2015, BIOCYC13B.