MetaCyc Gene-Ontology-Terms Class: GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system

Definition: The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.

Parent Classes:
GO:0008643 - carbohydrate transport

Term Members:
predicted PTS permease - SgcB subunit ,
AgaX (yadI) ,
predicted PTS permease - FrvB subunit ,
fructose PTS permease - FruA subunit ,
predicted PTS permease - SgcC subunit ,
predicted PTS permease - FrwB subunit ,
fructose PTS permease - FruB subunit ,
predicted PTS permease - FrwC subunit ,
predicted PTS permease - FrvA subunit ,
predicted PTS permease - SgcA subunit ,
GlvB subunit of predicted PTS permease (pseudogene) ,
dihydroxyacetone kinase subunit M (dhaM) ,
MalX PTS permease ,
NagE ,
2-O-α-mannosyl-D-glycerate PTS permease (mngA) ,
chitobiose PTS permease ,
chitobiose PTS permease - ChbB subunit ,
chitobiose PTS permease - ChbC subunit ,
chitobiose PTS permease - ChbA subunit ,
galactitol / sorbitol PTS permease ,
galactitol PTS permease - GatA subunit ,
galactitol PTS permease - GatB subunit ,
galactitol PTS permease - GatC subunit ,
L-ascorbate PTS permease ,
L-ascorbate PTS permease - UlaA subunit ,
L-ascorbate PTS permease - UlaB subunit ,
L-ascorbate PTS permease (ulaC) ,
AscF monomer ,
glucose PTS permease ,
glucose PTS permease - PtsG subunit ,
mannose PTS permease ,
mannose PTS permease - ManX subunit ,
mannose PTS permease - ManY subunit ,
mannose PTS permease - ManZ subunit ,
BglF ,
trehalose PTS permease - TreB subunit ,
N-acetylmuramic acid PTS permease ,
Enzyme IIAGlc; Crr ,
N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease (murP) ,
predicted PTS permease CmtBA ,
predicted PTS permease - CmtA subunit ,
predicted PTS permease - CmtB subunit ,
MtlA ,
sorbitol PTS permease ,
sorbitol PTS permease - SrlE subunit ,
sorbitol PTS permease - SrlB subunit ,
sorbitol PTS permease - SrlA subunit ,
HPr (ptsH)

Unification Links: GO:0009401

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc13.