Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store

MetaCyc Gene-Ontology-Terms Class: GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system

Definition: The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.

Parent Classes:
GO:0008643 - carbohydrate transport

Term Members:
predicted PTS permease - SgcB subunit,
predicted PTS permease - FrwC subunit,
predicted PTS permease - FrvA subunit,
predicted PTS permease - SgcA subunit,
GlvB subunit of predicted PTS permease (pseudogene),
AgaX (yadI),
predicted PTS permease - FrvB subunit,
fructose PTS permease - FruA subunit,
predicted PTS permease - SgcC subunit,
predicted PTS permease - FrwB subunit,
fructose PTS permease - FruB subunit,
dihydroxyacetone kinase subunit M (dhaM),
MalX PTS permease,
2-O-α-mannosyl-D-glycerate PTS permease (mngA),
chitobiose PTS permease,
chitobiose PTS permease - ChbB subunit,
chitobiose PTS permease - ChbC subunit,
chitobiose PTS permease - ChbA subunit,
galactitol / sorbitol PTS permease,
galactitol PTS permease - GatA subunit,
galactitol PTS permease - GatB subunit,
galactitol PTS permease - GatC subunit,
L-ascorbate PTS permease,
L-ascorbate PTS permease - UlaA subunit,
L-ascorbate PTS permease - UlaB subunit,
L-ascorbate PTS permease (ulaC),
AscF monomer,
glucose PTS permease,
glucose PTS permease - PtsG subunit,
mannose PTS permease,
mannose PTS permease - ManX subunit,
mannose PTS permease - ManY subunit,
mannose PTS permease - ManZ subunit,
trehalose PTS permease - TreB subunit,
N-acetylmuramic acid PTS permease,
Enzyme IIAGlc; Crr,
N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease (murP),
predicted PTS permease CmtBA,
predicted PTS permease - CmtA subunit,
predicted PTS permease - CmtB subunit,
sorbitol PTS permease,
sorbitol PTS permease - SrlE subunit,
sorbitol PTS permease - SrlB subunit,
sorbitol PTS permease - SrlA subunit,
HPr (ptsH)

Unification Links: GO:0009401

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue May 3, 2016, biocyc14.