MetaCyc Gene-Ontology-Terms Class: GO:0016651 - oxidoreductase activity, acting on NAD(P)H

Definition: Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

Note that enzymes of class EC:1.6.99.- should also be annotated to this term.

Parent Classes:
GO:0016491 - oxidoreductase activity

Child Classes:
GO:0003954 - NADH dehydrogenase activity (32),
GO:0016652 - oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor (6),
GO:0016653 - oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor (1),
GO:0016655 - oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (25),
GO:0016657 - oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor (5),
GO:0016668 - oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor (10)

Term Members:
NADH:ubiquinone oxidoreductase, chain CD (nuoC),
NADH:ubiquinone oxidoreductase, chain F (nuoF),
NADH:ubiquinone oxidoreductase, chain G (nuoG),
NADH:ubiquinone oxidoreductase, chain I (nuoI),
NADH:ubiquinone oxidoreductase, membrane subunit K (nuoK),
NADH:ubiquinone oxidoreductase, membrane subunit A (nuoA),
NADH oxidoreductase (hcr),
hydrogenase 3, large subunit (hycE),
Cb-eugenol synthase (CbEGS2),
Cb-isoeugenol synthase (CbIGS1),
eugenol synthase (EGS1),
eugenol synthase (EGS1),
isoeugenol synthase (IGS1)

Unification Links: GO:0016651

Relationship Links: ENZYME:RELATED-TO:1.6, Reactome:RELATED-TO:REACT_164, Reactome:RELATED-TO:REACT_32648, Reactome:RELATED-TO:REACT_79787, Reactome:RELATED-TO:REACT_81411, Reactome:RELATED-TO:REACT_87412, Reactome:RELATED-TO:REACT_87857, Reactome:RELATED-TO:REACT_87883, Reactome:RELATED-TO:REACT_89599, Reactome:RELATED-TO:REACT_94209, Reactome:RELATED-TO:REACT_101516, Reactome:RELATED-TO:REACT_108125

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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