MetaCyc Gene-Ontology-Terms Class: GO:0030163 - protein catabolic process

Synonyms: protein breakdown, protein catabolism, protein degradation

Definition: The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.

Parent Classes:
GO:0009057 - macromolecule catabolic process,
GO:0019538 - protein metabolic process

Child Classes:
GO:0006516 - glycoprotein catabolic process (1),
GO:0010498 - proteasomal protein catabolic process (1),
GO:0044257 - cellular protein catabolic process

Term Members:
leucyl, phenylalanyl-tRNA-protein transferase (aat),
tail-specific protease (prc),
ATP-dependent zinc metalloprotease FtsH,
peptidase component of the HslVU protease

Unification Links: GO:0030163

Relationship Links: Wikipedia:RELATED-TO:Protein_catabolism

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Sun Nov 29, 2015, BIOCYC13B.