MetaCyc Gene-Ontology-Terms Class: GO:0050660 - flavin adenine dinucleotide binding

Synonyms: FAD or FADH2 binding, flavine-adenine dinucleotide binding

Definition: Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.

Parent Classes:
GO:0050662 - coenzyme binding,
GO:0043168 - anion binding,
GO:0000166 - nucleotide binding

Child Classes:
GO:0071949 - FAD binding (17)

Term Members:
fused predicted xanthine/hypoxanthine oxidase: molybdopterin-binding subunit and Fe-S binding subunit (xdhD),
choline dehydrogenase (betA),
glycerol-3-phosphate dehydrogenase, anaerobic,
anaerobic glycerol-3-phosphate dehydrogenase subunit A (glpA),
glycolate oxidase, predicted FAD-binding subunit (glcE),
glycolate oxidase, predicted FAD-linked subunit (glcD),
UDP-N-acetylenolpyruvoylglucosamine reductase (murB),
3-phenylpropionate dioxygenase, predicted ferredoxin reductase subunit (hcaD),
xanthine dehydrogenase subunit, FAD-binding domain (xdhB),
xanthine dehydrogenase subunit (xdhA),
D-lactate dehydrogenase (dld),
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase (ubiF),
2-octaprenyl-6-methoxyphenol hydroxylase (ubiH),
2-octaprenylphenol hydroxylase (ubiI),
succinate:quinone oxidoreductase, FAD binding protein (sdhA),
malate:quinone oxidoreductase (mqo),
ring 1,2-phenylacetyl-CoA epoxidase, reductase subunit (paaE),
acetohydroxy acid synthase I, large subunit (ilvB),
UDP-galactopyranose mutase (glf),
fumarate reductase flavoprotein (frdA),
acyl-CoA dehydrogenase (fadE),
predicted enoyl-CoA reductase (ydiO),
thioredoxin reductase monomer (trxB),
glutathione reductase (NADPH) (gor),
fused PutA transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase,
tRNA-dihydrouridine synthase A (dusA),
tRNA-dihydrouridine synthase B (dusB),
tRNA-dihydrouridine synthase C (dusC),
sulfite reductase, flavoprotein subunit (cysJ),
NADH:quinone oxidoreductase II (ndh),
L-aspartate oxidase (nadB),
L-2-hydroxyglutarate oxidase (lhgO),
NAD(P)H:quinone oxidoreductase (wrbA),
ferric reductase, NADPH-dependent (yqjH),
aldehyde dehydrogenase: molybdenum cofactor-binding subunit (paoC),
aldehyde dehydrogenase, FAD-binding subunit (paoB),
E3 monomer (lpd),
NADH oxidoreductase (hcr),
alkyl hydroperoxide reductase, AhpF component,
protein involved in modification of U34 in tRNA (mnmG),
fused 5-methylaminomethyl-2-thiouridine-forming methyltransferase and FAD-dependent demodification enzyme (mnmC),
NADPH quinone reductase monomer (mdaB),
nitrite reductase, large subunit (nirB),
pyruvate oxidase monomer (poxB),
pyridine nucleotide transhydrogenase, soluble (sthA),
N-methyltryptophan oxidase (solA),
glycine oxidase monomer (thiO),
phthalate 3,4-dioxygenase ferredoxin reductase subunit (padAd1)

Unification Links: GO:0050660

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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