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discounted EARLY registration ends Dec 31, 2014
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
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MetaCyc Protein Class: a modified protein

Summary:
This class describes proteins that have been covalently modified, such as by the addition of a phosphate group.

Child Classes: (R)-β-hydroxy-L-tyrosine-S-[NovH protein] (0) , (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] (0) , 2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] (0) , a methylated corrinoid protein (0) , a palmitoylglycoprotein (0) , a (3S)-3-hydroxy-L-asparagine-HIF α subunit (0) , a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA-[acp] (0) , a 2,3-dehydro-decanoyl-HmqF (0) , a 3,4-DHB-AsbD protein (0) , a 4-(γ-L-glutamylamino)-(S)-2-hydroxy-butanoyl-[BtrI acyl-carrier protein] (0) , a 4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] (0) , a 4-amino butanoyl-[BtrI acyl-carrier protein] (0) , a 5-L-glutamyl-[peptide] (0) , a 5-oxoprolyl-peptide (0) , a biotinylated [BCCP dimer] (1) , a biotinylated [BCCP monomer] (1) , a C5a anaphylatoxin (0) , a caldesmon phosphate (0) , a carboxy-adenylated small subunit of molybdopterin synthase (0) , a carboxy-adenylated-[ThiS sulfur-carrier protein] (1) , a carboxyadenylated CysO sulfur-carrier protein (0) , a carboxylated-biotinylated [BCCP dimer] (1) , a cell division inhibitor SulA (0) , a citryl-[holo citrate lyase acyl-carrier protein] (0) , a cleaved angiotensinogen (0) , a cleaved PqqA peptide C-terminus (0) , a cleaved PqqA peptide N-terminus (0) , a cleaved synthetic tetradecapeptide renin (0) , a cleaved type IV prepillin (0) , a complement 5 α chain (0) , a complement 5 β chain (0) , a complement C5 α' chain (0) , a decanoyl-HmqF protein (0) , a degradation product of SulA (0) , a diacylglycerol prolipoprotein (0) , a factor Va (0) , a factor VIIa (0) , a factor VIIIa (0) , a factor IXa (0) , a factor Xa (0) , a factor XIa (0) , a glucosyl-glycogenin (1) , a glycoprotein (0) , a GST-related dithiol glutaredoxin (oxidized) (0) , a holo aryl-carrier protein (1) , a holo carbon monoxide dehydrogenase (0) , a holo [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] (0) , a holo-AsbD protein (0) , a holo-[acyl-carrier protein] (2) , a hydroxymethylglutaryl-CoA reductase (NADPH) phosphate (0) , a large subunit of hydrogenase 3 (0) , a lipoprotein (0) , a lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose (0) , a lysosomal-enzyme-D-mannose (0) , a malonyl-[holo malonate decarboxylase acyl-carrier protein] (0) , a mature P17 matrix (0) , a mature small ubiquitin-like modifier (SUMO) peptide (0) , a metarhodopsin II (0) , a methylated protein (0) , a methylated ribosomal protein L11 (0) , a modified pks13 polyketide synthase (0) , a myosin-heavy chain-phosphate (0) , a N-formylmethionyl peptide (0) , a p24 capsid protein (0) , a palmitoylated protein (0) , a phosphoprotein (0) , a phosphorhodopsin (0) , a phosphorylated pyruvate kinase (0) , a polyketide-[acp] (0) , a PqqA peptide (1) , a PqqA peptide with linked Glu-Tyr residues (0) , a protein with correct disulfide bonds (0) , a protein with incorrect disulfide bonds (0) , a protein with LPXTG motif (0) , a protein with NXTN motif (0) , a protein with sequence GKFKK (0) , a protein with sequence SGFRK-NH2 (0) , a protein with sequence SGVFTQ (0) , a protein with sequence SGVTFQGKFKK (0) , a protein with sequence TSAVLQSGFRK-NH2 (0) , a protein with-sequence TSAVLQ (0) , a protein-α-D-glucosyl-1,2-β-D-galactosyl-L-hydroxylysine (0) , a protein-β-D-galactosyl-L-hydroxylysine (0) , a proteoglycan (0) , a renin-2 heavy chain (1) , a renin-2 light chain (1) , a rhodopsin (0) , a rhodopsin Rh1 (0) , a SpoIVB peptidase (0) , a sulfurated [MtaB protein] (0) , a sulfurylated sulfur-binding protein (0) , a sulfurylated sulfur-carrier protein ThiF (0) , a thiocarboxy-adenylated-[ThiS-Protein] (0) , a thiocarboxylated small subunit of molybdopterin synthase (0) , a thiocarboxylated [CysO sulfur-carrier protein] (0) , a ThiS-ThiF acyl-disulfide (1) , a ThiS-ThiI acyl-disulfide (0) , a trans-4-hydroxy-L-proline-HIF α subunit (0) , a uridylylated PII protein (1) , a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine (0) , a [Co(II) dimethylamine-specific corrinoid protein] (0) , a [Co(II) methylamine-specific corrinoid protein] (0) , a [Co(II) trimethylamine-specific corrinoid protein] (0) , a [CysO sulfur-carrier protein]-S-L-cysteine (0) , a [formate C acetyltransferase]-glycin -2-yl radical (0) , a [formate C acetyltransferase]-glycine (0) , a [methionine synthase]-cob(I)alamin (0) , a [methionine synthase]-cob(II)alamin (0) , a [protein]-3-O-L-fucosyl-L-serine (0) , a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine (0) , a [protein]-N6-(O3)-phospho-D-erythrulosyl-L-lysine (0) , a [protein]-N6-(O3)-phospho-D-psicosyl-L-lysine (0) , a [protein]-N6-(O3-phospho-D-erythrulosyl-L-lysine (0) , a [protein]-N6-D-erythrulosyl-L-lysine (0) , a [protein]-N6-D-erythrulosyl-L-lysine (0) , a [protein]-N6-D-psicosyl-L-lysine (0) , a [protein]-N6-D-ribulosyl-L-lysine (0) , a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine (0) , a [pyruvate,phosphate dikinase]-phosphate (0) , acrosin (0) , activated complement subcomponent C1s (0) , active clotting enzyme (0) , ADP-D-ribosyl-(dinitrogen reductase) (0) , α-D-mannosyl-(1→6)-α-D-mannosyl-R (0) , an 11-cis retinol-[cellular-retinol-binding-protein] (0) , an 11-cis-retinal-[interphotoreceptor retinoid-binding protein] (0) , an 11-cis-retinal-[retinal-binding protein] (0) , an 11-cis-retinol-[retinal-binding protein] (0) , an acetyl-[holo citrate lyase acyl-carrier protein] (1) , an acetyl-[holo malonate decarboxylase acyl-carrier protein] (0) , an activated factor B (0) , an activated protein C (0) , an active hydrogenase subunit (0) , an active TNF-α (0) , an acyl-protein thioester (2) , an acyl-[acyl-carrier protein] (2) , an all-trans retinal-[cellular-retinol-binding-protein] (0) , an all-trans retinol-[cellular-retinol-binding-protein] (0) , an all-trans-3-hydroxyretinol-[retinoid-binding protein] (0) , an all-trans-retinal-[retinal-binding protein] (0) , an all-trans-retinol-(plasma-retinol-binding-protein) (0) , an archaeal flagellin (0) , an iron-sulfur protein (6) , an L-glutaminyl-peptide (0) , an L-glutamyl-[BtrI acyl-carrier protein] (0) , an N-acylated peptide (0) , an Nα-acetyl-peptide (0) , an oxidized cytochrome c550 (0) , an oxidized cytochrome cL (0) , an oxidized electron-transfer flavoprotein (0) , an oxidized ferredoxin (1) , an oxidized flavodoxin (2) , an oxidized flavoprotein (0) , an oxidized glutaredoxin (1) , an oxidized nitrogenase (1) , an oxidized nitrogenase-reductase (1) , an oxidized plastocyanin (0) , an oxidized putidaredoxin (0) , an oxidized rubredoxin (0) , an oxidized thioredoxin (2) , an oxidized transferrin (0) , an S-sulfanyl-[L-cysteine desulfurase] (0) , an S-sulfanyl-[ThiI sulfur-carrier protein] (0) , an [acetyl-CoA carboxylase] phosphate (0) , an [Fe-S cluster biosynthesis chaperone]-ATP (0) , an [FeS cluster biosynthesis chaperone]-ADP (0) , β aspartyl peptide (0) , β-oxo-L-tyrosine-S-[NovH protein] (0) , citramalate lyase, active (1) , cleaved flavivirus polyprotein (0) , cleaved helper component proteinase (0) , cleaved repressor LexA (0) , fragments of semenogelin-1 (0) , Glc-β-EGF-like domain (0) , L-tyrosine-S-[NovH protein] (0) , mature pro-interleukin-1β (0) , N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-α-D-mannosyl-R (0) , N-acetyl-β-D-glucosaminyl-(1→2)-[N-acetyl-β-D-glucosaminyl-(1→4)]-α-D-mannosyl-(1→3)-β-D-mannosyl-R (0) , O-β-D-GlcNAc-fucosyl-protein (0) , phospho-ERK (0) , phospho-MEK (0) , picornavirus polyprotein fragment (0) , poliovirus polyprotein fragment (0) , potyvirus polyprotein fragments (1) , smaller subunit of tyrosine aminotransferase (0) , Xyl-α(1-3)-Glc-β-EGF-like domain (0) , Xyl-α(1-3)-Xyl-α(1-3)-Glc-β-EGF-like domain (0) , [a biotinylated MadF protein] (0) , [a carboxylated biotinylated MadF protein] (0) , [a holo citrate lyase acyl-carrier protein] (2) , [a pyruvate, water dikinase]-phosphate (0) , [myelin proteolipid] (0)

Instances:
α cleavage product of IaaA (Escherichia coli K-12 substr. MG1655) ,
α cleavage product of SpeD (Escherichia coli K-12 substr. MG1655) ,
β cleavage product of IaaA (Escherichia coli K-12 substr. MG1655) ,
β cleavage product of SpeD (Escherichia coli K-12 substr. MG1655) ,
β-glucoside PTS permease BglF - cys24 phosphorylated (cryptic) (Escherichia coli K-12 substr. MG1655) ,
β-hexosaminidase subunit β chain A (Homo sapiens) ,
β-hexosaminidase subunit β chain B (Homo sapiens) ,
β-hydroxy-cis-Δ5-dodecenoyl-ACP ,
β-keto-cis-Δ5-dodecenoyl-ACP ,
β-peptidyl aminopeptidase α subunit (Sphingosinicella xenopeptidilytica) ,
β-peptidyl aminopeptidase β subunit (Sphingosinicella xenopeptidilytica) ,
γ-glutamyl transpeptidase large subunit (Homo sapiens) ,
γ-glutamyl transpeptidase small subunit (Homo sapiens) ,
γ-glutamyltransferase 5 large subunit (Homo sapiens) ,
γ-glutamyltransferase 5 small subunit (Homo sapiens) ,
γ-glutamyltranspeptidase, large subunit (Escherichia coli K-12 substr. MG1655) ,
γ-glutamyltranspeptidase, small subunit (Escherichia coli K-12 substr. MG1655) ,
(1,4-α-D-glucosyl)n-glucosyl glucogenin ,
(3R)-3-hydroxyoctanoyl-ACP ,
2-hexadecenoyl-ACP ,
2-ketobutyrate formate-lyase / pyruvate formate-lyase 4 (Escherichia coli K-12 substr. MG1655) ,
2-octenoyl-ACP ,
3R-3-hydroxybutanoyl-ACP ,
23-kDa subunit ([Clostridium] sticklandii) ,
45-kDa subunit ([Clostridium] sticklandii) ,
50S ribosomal subunit protein L7 (Escherichia coli K-12 substr. MG1655) ,
holo-DhbF protein (Bacillus subtilis) ,
N-acetylglucosamine-6-sulfatase 32 kDa chain (Homo sapiens) ,
N-acetylglucosamine-6-sulfatase 48 kDa chain (Homo sapiens) ,
S-adenosylmethionine decarboxylase α subunit (Homo sapiens) ,
S-adenosylmethionine decarboxylase β subunit (Homo sapiens) ,
Vibrio cholerae holo-VibF protein (Vibrio cholerae) ,
Vibrio cholerae holo-VibB protein monomer (Vibrio cholerae) ,
a factor XIIa ,
AceF-dihydrolipoate (Escherichia coli K-12 substr. MG1655) ,
AceF-lipoate (Escherichia coli K-12 substr. MG1655) ,
AceF-S-acetyldihydrolipoate (Escherichia coli K-12 substr. MG1655) ,
activated Fe hydrogenase ,
ADAMTS-4 endopeptidase (Homo sapiens) ,
adenylyl-[glutamine synthetase] (Escherichia coli K-12 substr. MG1655) ,
arginine decarboxylase proenzyme cleavage product α subunit (Thermococcus kodakarensis KOD1) ,
arginine decarboxylase proenzyme cleavage product β subunit (Thermococcus kodakarensis KOD1) ,
aryl carrier protein / L-seryl-AMP synthase (Escherichia coli K-12 substr. MG1655) ,
biotinylated biotin-carboxyl carrier protein (Escherichia coli K-12 substr. MG1655) ,
but-2-enoyl-ACP ,
C-terminal fragment (Pseudomonas aeruginosa) ,
carboxybiotin-carboxyl-carrier protein (Escherichia coli K-12 substr. MG1655) ,
CH3-MtaC-cob(I)amide (Methanosarcina barkeri) ,
CheB-Pasp (Escherichia coli K-12 substr. MG1655) ,
choline trimethylamine-lyase (Desulfovibrio alaskensis G20) ,
cis-Δ3-decenoyl-ACP ,
cis-Δ5-dodecenoyl-ACP ,
cis-3,4-dehydrodecanoyl-ACP ,
citrate lyase (Escherichia coli K-12 substr. MG1655) ,
corrinoid/iron-sulfur protein, methylated (Moorella thermoacetica) ,
dihydromonacolin L-[lovastatin nonaketide synthase] ,
dipeptidyl-peptidase 1 exclusion domain chain (Homo sapiens) ,
dipeptidyl-peptidase 1 heavy chain (Homo sapiens) ,
dipeptidyl-peptidase 1 light chain (Homo sapiens) ,
diphtheria toxin fragment A (Corynephage beta) ,
diphtheria toxin fragment B (Corynephage beta) ,
DsbGoxidized (Escherichia coli K-12 substr. MG1655) ,
EntB isochorismatase / aryl-carrier protein (Escherichia coli K-12 substr. MG1655) ,
factor X heavy chain (Homo sapiens) ,
factor X light chain (Homo sapiens) ,
factor Xa (Homo sapiens) ,
glutaminase kidney isoform large subunit (Homo sapiens) ,
glutaminase kidney isoform small subunit (Homo sapiens) ,
H-protein-(lipoyl)lysine (Gallus gallus) ,
heparanase 8 kDa subunit (Homo sapiens) ,
heparanase 50 kDa subunit (Homo sapiens) ,
histidine decarboxylase cleavage product α chain (Lactobacillus sp. 30A) ,
histidine decarboxylase cleavage product β chain (Lactobacillus sp. 30A) ,
HIV-2 retropepsin (Human immunodeficiency virus type 2 (ISOLATE ROD)) ,
holo-[acyl-carrier protein] (Escherichia coli K-12 substr. MG1655) ,
HPr - phosphorylated ,
HypE-S-carboxamide (Escherichia coli K-12 substr. MG1655) ,
iduronate 2-sulfatase 14 kDa chain (Homo sapiens) ,
iduronate 2-sulfatase 42 kDa chain (Homo sapiens) ,
insulin A chain (Homo sapiens) ,
insulin B chain (Homo sapiens) ,
isoaspartyl peptidase/L-asparaginase alpha chain (Homo sapiens) ,
isoaspartyl peptidase/L-asparaginase beta chain (Homo sapiens) ,
isocitrate dehydrogenase-P (Escherichia coli K-12 substr. MG1655) ,
L-histidine decarboxylase C-terminally truncated subunit (Rattus norvegicus) ,
lactyl-CoA dehydratase ([Clostridium] propionicum) ,
lipoyl-GcvH-protein (Escherichia coli K-12 substr. MG1655) ,
MoaD-S (Escherichia coli K-12 substr. MG1655) ,
Modified PSI-N ,
Modified purple acid phosphatase [multifunctional] ,
myeloperoxidase heavy chain (Homo sapiens) ,
myeloperoxidase light chain (Homo sapiens) ,
N-terminal fragment (Pseudomonas aeruginosa) ,
oxidized ferredoxin (Escherichia coli K-12 substr. MG1655) ,
oxidized flavorubredoxin (Escherichia coli K-12 substr. MG1655) ,
oxidized glutaredoxin 1 (Escherichia coli K-12 substr. MG1655) ,
oxidized glutaredoxin 2 (Escherichia coli K-12 substr. MG1655) ,
oxidized putidaredoxin ,
oxidized ribonucleoside-triphosphate reductase (Escherichia coli K-12 substr. MG1655) ,
oxidized thioredoxin (Escherichia coli K-12 substr. MG1655) ,
oxidized thioredoxin 2 (Escherichia coli K-12 substr. MG1655) ,
PanD α cleavage product (Escherichia coli K-12 substr. MG1655) ,
PanD β cleavage product (Escherichia coli K-12 substr. MG1655) ,
penicillin amidase α subunit (Escherichia coli W) ,
penicillin amidase β subunit (Escherichia coli W) ,
phosphatidylserine decarboxylase alpha chain (Homo sapiens) ,
phosphatidylserine decarboxylase beta subunit (Homo sapiens) ,
phosphatidylserine decarboxylase, α subunit (Escherichia coli K-12 substr. MG1655) ,
phosphatidylserine decarboxylase, β subunit (Escherichia coli K-12 substr. MG1655) ,
phosphoglycerol transferase II (Escherichia coli K-12 substr. MG1655) ,
phosphorylated serine/threonine kinase HipA (Escherichia coli K-12 substr. MG1655) ,
plasmin large subunit (Homo sapiens) ,
plasmin small subunit (Homo sapiens) ,
protein chain elongation factor EF-P, β-lysyl-Lys34 ,
protein disulfide isomerase/protein disulfide oxidoreductase - DsbCoxidised (Escherichia coli K-12 substr. MG1655) ,
protein disulfide oxidoreductase - DsbAoxidised (Escherichia coli K-12 substr. MG1655) ,
protein disulfide oxidoreductase - DsbBoxidised (Escherichia coli K-12 substr. MG1655) ,
protein disulfide oxidoreductase - DsbDoxidized (Escherichia coli K-12 substr. MG1655) ,
PtsP-phosphorylated ,
pyruvate formate-lyase / 2-ketobutyrate formate-lyase (Escherichia coli K-12 substr. MG1655) ,
R-3-hydroxypalmitoyl-ACP ,
ricin A chain (Ricinus communis) ,
ricin B chain (Ricinus communis) ,
SoxD (Paracoccus pantotrophus) ,
SucB-dihydrolipoate (Escherichia coli K-12 substr. MG1655) ,
SucB-lipoate (Escherichia coli K-12 substr. MG1655) ,
SucB-S-succinyldihydrolipoate (Escherichia coli K-12 substr. MG1655) ,
succ-ACP ,
sucrose:fructan 6-fructosyltransferase 23 kDa subunit (Hordeum vulgare) ,
sucrose:fructan 6-fructosyltransferase 49 kDa subunit (Hordeum vulgare) ,
trans-Δ3-cis-Δ5-dodecenoyl-ACP ,
type IV collagenase (Homo sapiens) ,
uridylyl-[GlnK] (Escherichia coli K-12 substr. MG1655) ,
xanthine oxidase (Homo sapiens) ,
xanthine oxidase monomer (Homo sapiens)


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC13B.