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MetaCyc Compound Class: a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine

Superclasses: an amino acid or its derivative a [protein]-amino acid a modified amino acid within a protein a [lipoyl-carrier protein] N6-octanoyl-L-lysine

a [glycine-cleavage complex H protein] <i>N<sup>6</sup></i>-octanoyl-L-lysine compound structure

SMILES: CCCCCCCC(=O)NCCCCC(C(=O)[a glycine-cleavage complex H protein])N[a glycine-cleavage complex H protein]

Reactions known to consume the compound:

lipoate biosynthesis and incorporation (glycine cleavage system, yeast) :
a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 S-adenosyl-L-methionine + 2 a sulfurated [sulfur carrier] + 2 a reduced [2Fe-2S] ferredoxin → a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 L-methionine + 2 5'-deoxyadenosine + 2 an unsulfurated [sulfur carrier] + 2 an oxidized [2Fe-2S] ferredoxin

lipoate biosynthesis and incorporation III (Bacillus) :
a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a [lipoyl-carrier protein]-L-lysine → [glycine cleavage system lipoyl-carrier protein]-L-lysine + a [lipoyl-carrier protein] N6-octanoyl-L-lysine

lipoate biosynthesis and incorporation I , lipoate biosynthesis and incorporation II , lipoate biosynthesis and incorporation III (Bacillus) :
a [lipoyl-carrier protein] N6-octanoyl-L-lysine + 2 S-adenosyl-L-methionine + 2 a sulfurated [sulfur carrier] + 2 a reduced [2Fe-2S] ferredoxin → a [lipoyl-carrier protein] N6-lipoyl-L-lysine + 2 5'-deoxyadenosine + 2 L-methionine + 2 an unsulfurated [sulfur carrier] + 2 an oxidized [2Fe-2S] ferredoxin

Reactions known to produce the compound:

lipoate biosynthesis and incorporation (glycine cleavage system, yeast) , lipoate biosynthesis and incorporation III (Bacillus) :
an octanoyl-[acp] + [glycine cleavage system lipoyl-carrier protein]-L-lysine → a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein] + H+

lipoate biosynthesis and incorporation I :
an octanoyl-[acp] + a [lipoyl-carrier protein]-L-lysine → a [lipoyl-carrier protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein] + H+

lipoate biosynthesis and incorporation II :
a [lipoyl-carrier protein]-L-lysine + octanoate + ATP → a [lipoyl-carrier protein] N6-octanoyl-L-lysine + AMP + diphosphate + H+


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Aug 30, 2015, biocyc14.