Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Compound Class: a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine

Superclasses: an amino acid or its derivative a [protein]-amino acid a modified amino acid within a protein a [lipoyl-carrier protein] N6-octanoyl-L-lysine

SMILES: CCCCCCCC(=O)NCCCCC(C(=O)[a glycine-cleavage complex H protein])N[a glycine-cleavage complex H protein]

Reactions known to consume the compound:

lipoate biosynthesis and incorporation (glycine cleavage system, yeast) :
a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 S-adenosyl-L-methionine + 2 a sulfurated [sulfur carrier] → a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 L-methionine + 2 5'-deoxyadenosine + 2 an unsulfurated [sulfur carrier]

lipoate biosynthesis and incorporation III (Bacillus) :
a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a [lipoyl-carrier protein]-L-lysine → [glycine cleavage system lipoyl-carrier protein]-L-lysine + a [lipoyl-carrier protein] N6-octanoyl-L-lysine

lipoate biosynthesis and incorporation I , lipoate biosynthesis and incorporation II , lipoate biosynthesis and incorporation III (Bacillus) :
a [lipoyl-carrier protein] N6-octanoyl-L-lysine + 2 S-adenosyl-L-methionine + 2 a sulfurated [sulfur carrier] → a [lipoyl-carrier protein] N6-lipoyl-L-lysine + 2 5'-deoxyadenosine + 2 L-methionine + 2 an unsulfurated [sulfur carrier]

Reactions known to produce the compound:

lipoate biosynthesis and incorporation (glycine cleavage system, yeast) :
octanoyl-ACP + [glycine cleavage system lipoyl-carrier protein]-L-lysine → a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein] + H+

lipoate biosynthesis and incorporation III (Bacillus) :
an octanoyl-[acp] + [glycine cleavage system lipoyl-carrier protein]-L-lysine → a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein] + H+

lipoate biosynthesis and incorporation I :
an octanoyl-[acp] + a [lipoyl-carrier protein]-L-lysine → a [lipoyl-carrier protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein] + H+

lipoate biosynthesis and incorporation II :
a [lipoyl-carrier protein]-L-lysine + octanoate + ATP → a [lipoyl-carrier protein] N6-octanoyl-L-lysine + AMP + diphosphate + H+


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, biocyc14.