Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Compound Class: a poly-β-hydroxybutyrate

Synonyms: poly-3-hydroxybutyrate, PHB, polyhydroxybutyrate, 2-methyl-3-ketobutyrate, poly-hydroxybutyrate

Superclasses: a secondary metabolite
an ester a poly[(R)-3-hydroxyalkanoate]

Summary:
During enzymatic polymerization the ester bond in this polymer is derived from the hydroxyl group of the (R)-3-hydroxybutanoyl moiety of (R)-3-hydroxybutanoyl-CoA [Jia01].

SMILES: CC(O[R])CC(=O)OC(C)CC(=O)OC(C)CC([O-])=O

Unification Links: KEGG:C06143 , Wikipedia:Polyhydroxybutyrate

Reactions known to consume the compound:

polyhydroxybutyrate biosynthesis :
(R)-3-hydroxybutanoyl-CoA + [(R)-3-hydroxybutanoate]n[(R)-3-hydroxybutanoate](n+1) + coenzyme A

Not in pathways:
[(R)-3-hydroxybutanoate]n + H2O → [(R)-3-hydroxybutanoate](n-1) + (R)-3-hydroxybutanoate

Credits:
Revised 16-Apr-2014 by Fulcher CA , SRI International


References

Jia01: Jia Y, Yuan W, Wodzinska J, Park C, Sinskey AJ, Stubbe J (2001). "Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism." Biochemistry 40(4);1011-9. PMID: 11170423


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, BIOCYC13B.