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discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reactions Class: tRNA-Reactions

Summary:
Reactions in which at least one substrate is a tRNA or a modified tRNA.

Parent Classes:
RNA-Reactions

Child classes:
tRNA-Charging-Reactions (27)

Instances:
1.1.1.-: a 5,6-dihydrouridine in tRNA + NADP+ ← a uridine in tRNA + NADPH + H+ ,
1.2.1.70: glutamate-1-semialdehyde + tRNAGlu + NADP+ ← L-glutamyl-tRNAGlu + NADPH ,
1.3.1.88: a 5,6-dihydrouracil16 in tRNA + NAD(P)+ ← a uracil16 in tRNA + NAD(P)H + H+ ,
1.3.1.88: a 5,6-dihydrouracil17 in tRNA + NAD(P)+ ← a uracil17 in tRNA + NAD(P)H + H+ ,
1.3.1.89: a 5,6-dihydrouracil47 in tRNA + NAD(P)+ ← a uracil47 in tRNA + NAD(P)H + H+ ,
1.3.1.90: a 5,6-dihydrouracil20a in tRNA + NAD(P)+ ← a uracil20a in tRNA + NAD(P)H + H+ ,
1.3.1.90: a 5,6-dihydrouracil20b in tRNA + NAD(P)+ ← a uracil20b in tRNA + NAD(P)H + H+ ,
1.3.1.91: a 5,6-dihydrouracil20 in tRNA + NAD(P)+ ← a uracil20 in tRNA + NAD(P)H + H+ ,
1.17.99.a: a queuosine34 in tRNA + an oxidized electron acceptor + H2O ← an epoxyqueuosine34 in tRNA + a reduced electron acceptor ,
2.1.1.33: guanine46 in tRNA + S-adenosyl-L-methionine → N7-methylguanine46 in tRNA + S-adenosyl-L-homocysteine ,
2.1.1.34: a guanosine18 in tRNA + S-adenosyl-L-methionine → a 2'-O-methylguanosine18 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.35: a uracil54 in tRNA + S-adenosyl-L-methionine → a 5-methyluracil54 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.55: an adenine in tRNA + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + an N6-methyladenine in tRNA + H+ ,
2.1.1.61: a tRNA containing 5-aminomethyl-2-thiouridine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + a 5-methylaminomethyl-2-thiouridine in tRNA + 2 H+ ,
2.1.1.74: a 5,10-methylene-tetrahydrofolate + a uracil54 in tRNA + FADH2 = a tetrahydrofolate + a 5-methyluracil54 in tRNA + FAD + H+ ,
2.1.1.200: a cytidine 32 in tRNA + S-adenosyl-L-methionine → a 2'-O-methylcytidine32 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.200: a uridine32 in tRNA + S-adenosyl-L-methionine → a 2'-O-methyluridine32 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.202: S-adenosyl-L-methionine + a cytosine34 in tRNA precursor → S-adenosyl-L-homocysteine + a 5 methylcytosine34 in tRNA precursor ,
2.1.1.202: S-adenosyl-L-methionine + a cytosine40 in tRNA precursor → S-adenosyl-L-homocysteine + a 5 methylcytosine40 in tRNA precursor ,
2.1.1.202: S-adenosyl-L-methionine + a cytosine48 in tRNA → S-adenosyl-L-homocysteine + a 5-methylcytosine48 in tRNA + H+ ,
2.1.1.202: S-adenosyl-L-methionine + a cytosine49 in tRNA → S-adenosyl-L-homocysteine + a 5-methylcytosine49 in tRNA + H+ ,
2.1.1.203: S-adenosyl-L-methionine + a cytosine34 in tRNA precursor → S-adenosyl-L-homocysteine + a 5 methylcytosine34 in tRNA precursor ,
2.1.1.204: a cytosine38 in tRNA + S-adenosyl-L-methionine → a 5-methylcytosine38 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.205: a cytidine32/guanosine34 in tRNA + S-adenosyl-L-methionine → a 2'-O-methylcytidine32/2-O-methylguanosine34 in tRNA + S-adenosyl-L-homocysteine ,
2.1.1.206: a cytidine 56 in tRNA + S-adenosyl-L-methionine → a 2-O-methylcytidine56 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.207: a cytidine34 in tRNA + S-adenosyl-L-methionine → a 2'-O-methylcytidine34 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.207: a 5-carboxymethylaminomethyluridine34 in tRNALeu + S-adenosyl-L-methionine → a 5-carboxymethylaminomethyl-2'-O-methyluridine34 in tRNALeu + S-adenosyl-L-homocysteine + H+ ,
2.1.1.211: a uridine44 in tRNAser + S-adenosyl-L-methionine → a 2'-O-methyluridine44 in tRNAser + S-adenosyl-L-homocysteine + H+ ,
2.1.1.213: a guanine10 in tRNA + 2 S-adenosyl-L-methionine → N2-dimethylguanine10 in tRNA + 2 S-adenosyl-L-homocysteine + 2 H+ ,
2.1.1.214: a guanine10 in tRNA + S-adenosyl-L-methionine → an N2-methylguanine10 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.215: guanine26/guanine27 in tRNA + S-adenosyl-L-methionine → N2-methylguanine26/guanine27 in tRNA + S-adenosyl-L-homocysteine ,
2.1.1.215: N2-methylguanine26/guanine27 in tRNA + S-adenosyl-L-methionine → N2 dimethylguanine26/guanine27 in tRNA + S-adenosyl-L-homocysteine ,
2.1.1.215: N2 dimethylguanine26/guanine27 in tRNA + S-adenosyl-L-methionine → N2-dimethylguanine26/N2-methylguanine27 + S-adenosyl-L-homocysteine ,
2.1.1.215: N2-dimethylguanine26/N2-methylguanine27 + S-adenosyl-L-methionine → N2-dimethylguanine26/N2-dimethylguanine27 + S-adenosyl-L-homocysteine ,
2.1.1.215: guanine26/guanine27 in tRNA + 4 S-adenosyl-L-methionine → N2-dimethylguanine26/N2-dimethylguanine27 + 4 S-adenosyl-L-homocysteine ,
2.1.1.216: a guanine26 in tRNA + S-adenosyl-L-methionine → an N2-methylguanine26 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.216: S-adenosyl-L-methionine + an N2-methylguanine26 in tRNA → S-adenosyl-L-homocysteine + an N2dimethylguanine26 in tRNA + H+ ,
2.1.1.216: a guanine26 in tRNA + 2 S-adenosyl-L-methionine → an N2dimethylguanine26 in tRNA + 2 S-adenosyl-L-homocysteine + 2 H+ ,
2.1.1.217: an adenine22 in tRNA + S-adenosyl-L-methionine → N1-methyladenine22 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.218: an adenine9 in tRNA + S-adenosyl-L-methionine → N1-methyladenine9 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.219: an adenine57/adenine58 in tRNA + 2 S-adenosyl-L-methionine → N1-methyladenine57/N1-methyladenine58 in tRNA + 2 S-adenosyl-L-homocysteine ,
2.1.1.220: an adenine58 in tRNA + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + an N1-methyladenine58 in tRNA + H+ ,
2.1.1.221: guanine9 in tRNA + S-adenosyl-L-methionine → N1-methylguanine9 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.223: S-adenosyl-L-methionine + adenine37 in tRNA1valS-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1val + H+ ,
2.1.1.225: S-adenosyl-L-methionine + a cytidine4 in tRNAProS-adenosyl-L-homocysteine + a 2'-O-methylcytidine4 in tRNAPro + H+ ,
2.1.1.225: S-adenosyl-L-methionine + a cytidine4 in tRNAGly(GCC) → S-adenosyl-L-homocysteine + a 2'-O-methylcytidine4 in tRNAGly(GCC) ,
2.1.1.225: S-adenosyl-L-methionine + an adenosine4 in tRNAHisS-adenosyl-L-homocysteine + a 2'-O-methyladenosine4 in tRNAHis + H+ ,
2.1.1.228: guanine37 in tRNA + S-adenosyl-L-methionine → N1-methylguanine37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.228: guanine37 in tRNAPhe + S-adenosyl-L-methionine → N1-methylguanine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ ,
2.1.1.229: a carboxymethyluridine34 in tRNA + S-adenosyl-L-methionine → a 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine ,
2.1.1.256: a guanine6 in tRNA + S-adenosyl-L-methionine → an N2-methylguanine6 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.268: a cytosine32 in tRNAthr + S-adenosyl-L-methionine → an N3-methylcytosine32 in tRNAthr + S-adenosyl-L-homocysteine ,
2.1.1.268: a cytosine32 in tRNASer + S-adenosyl-L-methionine → an N3-methylcytosine32 in tRNASer + S-adenosyl-L-homocysteine ,
2.1.1.290: 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + S-adenosyl-L-methionine → 7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + S-adenosyl-L-homocysteine ,
2.1.1.290: 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe + S-adenosyl-L-methionine → 7-[4-methoxy-(2-hydroxy-3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + S-adenosyl-L-homocysteine ,
2.1.1.-: wyosine37 in tRNAPhe + S-adenosyl-L-methionine → 7-methylwyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: 4-demethylwyosine37 in tRNAPhe + S-adenosyl-L-methionine → wyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: isowyosine37 in tRNAPhe + S-adenosyl-L-methionine → 7-methylwyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: 4-demethylwyosine37 in tRNAPhe + S-adenosyl-L-methionine → isowyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ ,
2.1.2.9: an N10-formyl-tetrahydrofolate + L-methionyl-tRNAfmet → a tetrahydrofolate + N-formyl-L-methionyl-tRNAfmet ,
2.3.1.193: a cytidine34 in tRNAmet + ATP + acetyl-CoA + H2O → [elongator tRNAmet]-N4-acetylcytidine34 + ADP + coenzyme A + phosphate + H+ ,
2.3.2.3: an L-1-phosphatidyl-glycerol + L-lysyl-tRNAlys → 3-O-L-lysyl-1-O-phosphatidylglycerol + tRNAlys + H+ ,
2.3.2.6: a protein + L-leucyl-tRNAleu = tRNAleu + L-leucyl-[protein] + H+ ,
2.3.2.8: a protein + L-arginyl-tRNAarg = a [protein] with an N-terminal L-arginine + tRNAarg + H+ ,
2.3.2.10: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNAala → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNAala + 2 H+ ,
2.3.2.11: L-alanyl-tRNAala + an L-1-phosphatidyl-glycerol = tRNAala + 3-O-L-alanyl-1-O-phosphatidylglycerol ,
2.3.2.12: a peptidyl tRNA + a charged tRNA = a tRNA + a peptidyl aminoacyl tRNA ,
2.3.2.16: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNAaladitrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNAala ,
2.3.2.20: L-leucyl-tRNAleu + L-phenylalanyl-tRNAphe = tRNAleu + tRNAphe + cyclo(L-leucyl-L-phenylalanyl) ,
2.3.2.21: 2 L-tyrosyl-tRNAtyr → 2 tRNAtyr + cyclo-L-tyrosyl-L-tyrosyl + 2 H+ ,
2.3.2.21: L-seryl-tRNAser + L-tyrosyl-tRNAtyr = cyclo-L-tyrosyl-L-tyrosyl + tRNAtyr + tRNAser + 2 H+ ,
2.3.2.22: 2 L-leucyl-tRNAleu → cyclo(L-leucyl-L-leucyl) + 2 tRNAleu + 2 H+ ,
2.3.2.-: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + L-seryl-tRNAser → UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl-L-seryl)-L-lysyl-D-alanyl-D-alanine + tRNAser + 2 H+ ,
2.3.2.-: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNAala → UDP-N-acetylmuramoyl-L-alanyl-D-isglutaminyl-N6-(L-alanyl-L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNAala ,
2.4.1.110: queuosine at position 34 of a tRNAAsp + GDP-α-D-mannose = D-mannosyl-5'-O-β-queuosine at position 34 of a tRNAAsp + GDP + H+ ,
2.4.1.-: queuosine at position 34 of a tRNAAsp + ATP + L-glutamate → glutamyl-queuosine at position 34 of a tRNAAsp + AMP + diphosphate + 2 H+ ,
2.4.2.29: a guanine34 in tRNA + queuine + H+ = a queuosine34 in tRNA + guanine ,
2.4.2.29: a guanine34 in tRNA + preQ1 → a 7-aminomethyl-7-deazaguanosine34 in tRNA + guanine ,
2.4.2.48: guanine at position 15 of an archaeal tRNA + preQ0 → preQ0 at position 15 of an archaeal tRNA + guanine ,
2.4.99.17: a 7-aminomethyl-7-deazaguanosine34 in tRNA + S-adenosyl-L-methionine → an epoxyqueuosine34 in tRNA + adenine + L-methionine + 2 H+ ,
2.5.1.25: a uridine in tRNA + S-adenosyl-L-methionine = a tRNA 3-(3-amino-3-carboxypropyl)-uridine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.73: O-phospho-L-seryl-tRNACys + hydrogen sulfide → L-cysteinyl-tRNAcys + phosphate ,
2.5.1.75: dimethylallyl diphosphate + an adenosine37 in tRNA → N6-dimethylallyladenosine37 in tRNA + diphosphate ,
2.7.1.160: a 2'-phospho-[ligated tRNA] + NAD+ → an uncharged tRNA + ADP ribose 1'',2''-cyclic phosphate + nicotinamide + H2O ,
2.7.1.164: L-seryl-tRNAsec + ATP ↔ O-phospho-L-seryl-tRNASec + ADP ,
2.7.7.56: a tRNA precursor with a short 3' extension + n phosphate → an uncharged tRNA + n a ribonucleoside diphosphate ,
2.7.7.56: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate ,
2.7.7.72: a tRNA precursor + 2 CTP + ATP → a tRNA containing a 3' CCA end + 3 diphosphate ,
2.7.7.79: p-tRNAHis + ATP + GTP = pppGp-tRNAHis + AMP + diphosphate ,
2.7.7.79: p-tRNAHis + ATP = App-tRNAHis + diphosphate ,
2.7.7.79: App-tRNAHis + GTP = pppGp-tRNAHis + AMP ,
2.8.1.4: 'activated' tRNA + L-cysteine = L-serine + tRNA containing a thionucleotide ,
2.9.1.1: selenophosphate + L-seryl-tRNAsec → L-selenocysteinyl-tRNAsec + phosphate + H+ ,
2.9.1.2: O-phospho-L-seryl-tRNASec + selenophosphate + H2O → L-selenocysteinyl-tRNAsec + 2 phosphate + H+ ,
3.1.1.29: an N-modified aminoacyl-tRNA + H2O → a tRNA + an N-modified amino acid + 2 H+ ,
3.1.1.29: L-asparaginyl-tRNAasn + H2O → L-asparagine + tRNAasn + 2 H+ ,
3.1.1.96: a D-aminoacyl-tRNA + H2O → a D-amino acid + a tRNA + 2 H+ ,
3.1.13.1: mutated tRNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor + H2O → a tRNA + a nucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor with a short 3' extension → an uncharged tRNA + n a nucleoside 5'-monophosphate ,
3.1.26.5: a tRNA precursor with a 5' extension + H2O → an uncharged tRNA + a single-stranded RNA ,
3.5.1.27: an N-formyl-L-methionylaminoacyl-tRNA + H2O → a L-methionylaminoacyl-tRNA + formate + H+ ,
3.5.4.34: a adenine37 in tRNAala + H+ + H2O = a hypoxanthine37 in tRNAala + ammonium ,
3.5.4.-: an adenosine34 in [tRNAArg2] + H+ + H2O → an inosine34 in [tRNAArg2] + ammonium ,
5.4.99.12: a tRNA uridine38-40 → a pseudouridine38-40 in tRNA ,
5.4.99.42: a uridine31 in tRNA = a pseudouridine31 in tRNA ,
5.4.99.44: mitochondrial tRNA uridine 27/28 = mitochondrial tRNA pseudouridine 27/28 ,
5.4.99.45: a tRNA uridine38/39 = a pseudouridine38/39 in tRNA ,
5.4.99.-: a uridine54 in tRNA = a pseudouridine54 in tRNA ,
6.3.4.19: a cytidine34 in tRNAIle2 + L-lysine + ATP → a lysidine34 in tRNAIle2 + AMP + diphosphate + 2 H+ ,
6.3.5.6: L-glutamine + L-aspartyl-tRNAasn + ATP + H2O → L-glutamate + L-asparaginyl-tRNAasn + ADP + phosphate + H+ ,
6.3.5.7: L-glutamine + L-glutamyl-tRNAGln + ATP + H2O → L-glutamate + L-glutaminyl-tRNAgln + ADP + phosphate + H+ ,
6.5.1.-: a 5' half-tRNA molecule with a 2',3' cyclic phosphate on its 3' end + a 3' half-tRNA molecule with a hydroxyl on its 5' end + ATP → a 2'-phospho-[ligated tRNA] + AMP + diphosphate ,
cis-hydroxy-prenyl-tRNA → cis-zeatin riboside monophosphate ,
N6-dimethylallyladenosine37 in tRNA + a reduced electron acceptor + oxygen → cis-hydroxy-prenyl-tRNA + an oxidized electron acceptor + H2O ,
an N2-methylguanine10 in tRNA + S-adenosyl-L-methionine → N2-dimethylguanine10 in tRNA + S-adenosyl-L-homocysteine + H+ ,
a guanine10 in tRNA + S-adenosyl-L-methionine → an N2-methylguanine10 in tRNA + S-adenosyl-L-homocysteine + H+


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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