Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Compound: 8-oxo-dGMP

Synonyms: 8-oxo-7,8-dihydro-2'-dGMP, 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-monophosphate, 8-oxo-deoxyguanosine-monophosphate

Superclasses: a nucleic acid component

Citations: [Maki92]

Chemical Formula: C10H12N5O8P

Molecular Weight: 361.21 Daltons

Monoisotopic Molecular Weight: 363.0579989622 Daltons

SMILES: C(OP(=O)([O-])[O-])C1(OC(CC(O)1)N3(C(=O)NC2(C(=O)NC(N)=NC=23)))

InChI: InChI=1S/C10H14N5O8P/c11-9-13-7-6(8(17)14-9)12-10(18)15(7)5-1-3(16)4(23-5)2-22-24(19,20)21/h3-5,16H,1-2H2,(H,12,18)(H2,19,20,21)(H3,11,13,14,17)/p-2/t3-,4+,5+/m0/s1

InChIKey: InChIKey=AQIVLFLYHYFRKU-VPENINKCSA-L

Unification Links: ChEBI:63224 , PubChem:46173535

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -251.7538 Inferred by computational analysis [Latendresse13]

Reactions known to produce the compound:

oxidized GTP and dGTP detoxification :
8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+

Not in pathways:
8-oxo-dGDP + H2O → 8-oxo-dGMP + phosphate + H+

In Reactions of unknown directionality:

Not in pathways:
8-oxo-dGTP + 2 H2O = 8-oxo-dGMP + 2 phosphate + 2 H+

Credits:
Created 21-Apr-2010 by Dreher KA , TAIR


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Maki92: Maki H, Sekiguchi M (1992). "MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis." Nature 355(6357);273-5. PMID: 1309939


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC14B.