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discounted EARLY registration ends Dec 31, 2014
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discounted EARLY registration ends Dec 31, 2014
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discounted EARLY registration ends Dec 31, 2014
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MetaCyc Compound: 7,8-dihydroneopterin 3'-triphosphate

Synonyms: 6-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin, 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin, 6-(D-erythro-1',2',3'-trihydroxypropyl)-7,8-dihydropterin-3'-triphosphate, 7,8-dihydroneopterin 3'-triphosphate, 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate, dihydroneopterin triphosphate, H2NTP, 7,8-dihydroneopterin triphosphate

Superclasses: an organic heterocyclic compound an organic heterobicyclic compound a pteridine a pterin
an organic heterocyclic compound an organonitrogen heterocyclic compound a pteridine a pterin

Chemical Formula: C9H12N5O13P3

Molecular Weight: 491.14 Daltons

Monoisotopic Molecular Weight: 494.99574515689994 Daltons

SMILES: C1(NC2(N=C(N)NC(=O)C(N=C1C(O)C(O)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])=2))

InChI: InChI=1S/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/p-4/t4-,6+/m1/s1

InChIKey: InChIKey=DGGUVLXVLHAAGT-XINAWCOVSA-J

Unification Links: ChEBI:58462 , HMDB:HMDB00980 , IAF1260:44843 , KEGG:C04895 , MetaboLights:MTBLC58462 , PubChem:25201779

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -528.04956 Inferred by computational analysis [Latendresse13]

Reactions known to consume the compound:

6-hydroxymethyl-dihydropterin diphosphate biosynthesis I :
7,8-dihydroneopterin 3'-triphosphate + H2O → 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+

drosopterin and aurodrosopterin biosynthesis , tetrahydrobiopterin biosynthesis I , tetrahydrobiopterin biosynthesis II , tetrahydrobiopterin biosynthesis III :
7,8-dihydroneopterin 3'-triphosphate → 6-pyruvoyl tetrahydropterin + PPPi + H+

preQ0 biosynthesis :
7,8-dihydroneopterin 3'-triphosphate + H2O → 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + PPPi + 2 H+

Reactions known to produce the compound:

6-hydroxymethyl-dihydropterin diphosphate biosynthesis I , drosopterin and aurodrosopterin biosynthesis , preQ0 biosynthesis , tetrahydrobiopterin biosynthesis I , tetrahydrobiopterin biosynthesis II , tetrahydrobiopterin biosynthesis III :
GTP + H2O → formate + 7,8-dihydroneopterin 3'-triphosphate + H+

Reactions known to both consume and produce the compound:

tetrahydromonapterin biosynthesis :
7,8-dihydroneopterin 3'-triphosphate ↔ 7,8-dihydromonapterin triphosphate


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13B.