Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
twitter

MetaCyc Compound: guanosine tetraphosphate

Superclasses: a nucleic acid component
a nucleic acid component a base derivative

Chemical Formula: C10H13N5O17P4

Molecular Weight: 599.13 Daltons

Monoisotopic Molecular Weight: 602.9569901874 Daltons

SMILES: C2(=NC3(=C(N(C1(OC(COP(=O)([O-])OP(=O)(OP([O-])(OP([O-])(=O)O)=O)[O-])C(O)C(O)1))2)N=C(NC3=O)N))

InChI: InChI=1S/C10H17N5O17P4/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(29-9)1-28-34(22,23)31-36(26,27)32-35(24,25)30-33(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H,26,27)(H2,19,20,21)(H3,11,13,14,18)/p-4

InChIKey: InChIKey=KDFXXNGTULMGMF-UHFFFAOYSA-J

Unification Links: CAS:33503-72-9 , PubChem:46173110

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -751.0474 Inferred by computational analysis [Latendresse13]

Enzymes inhibited by guanosine tetraphosphate, sorted by the type of inhibition, are:

Inhibitor (Competitive) of: GTP cyclohydrolase [Yim76]

Inhibitor (Mechanism unknown) of: GTP cyclohydrolase [Foor75]


References

Foor75: Foor F, Brown GM (1975). "Purification and properties of guanosine triphosphate cyclohydrolase II from Escherichia coli." J Biol Chem 1975;250(9);3545-51. PMID: 235552

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Yim76: Yim JJ, Brown GM (1976). "Characteristics of guanosine triphosphate cyclohydrolase I purified from Escherichia coli." J Biol Chem 1976;251(16);5087-94. PMID: 821948


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc14.