Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Compound: guanosine tetraphosphate

Superclasses: a nucleic acid component
a nucleic acid component a base derivative

Chemical Formula: C10H13N5O17P4

Molecular Weight: 599.13 Daltons

Monoisotopic Molecular Weight: 602.9569901874 Daltons

SMILES: C2(=NC3(=C(N(C1(OC(COP(=O)([O-])OP(=O)(OP([O-])(OP([O-])(=O)O)=O)[O-])C(O)C(O)1))2)N=C(NC3=O)N))

InChI: InChI=1S/C10H17N5O17P4/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(29-9)1-28-34(22,23)31-36(26,27)32-35(24,25)30-33(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H,26,27)(H2,19,20,21)(H3,11,13,14,18)/p-4

InChIKey: InChIKey=KDFXXNGTULMGMF-UHFFFAOYSA-J

Unification Links: CAS:33503-72-9 , PubChem:46173110

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -751.0474 Inferred by computational analysis [Latendresse13]

Enzymes inhibited by guanosine tetraphosphate, sorted by the type of inhibition, are:

Inhibitor (Competitive) of: GTP cyclohydrolase [Yim76]

Inhibitor (Mechanism unknown) of: GTP cyclohydrolase [Foor75]


References

Foor75: Foor F, Brown GM (1975). "Purification and properties of guanosine triphosphate cyclohydrolase II from Escherichia coli." J Biol Chem 1975;250(9);3545-51. PMID: 235552

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Yim76: Yim JJ, Brown GM (1976). "Characteristics of guanosine triphosphate cyclohydrolase I purified from Escherichia coli." J Biol Chem 1976;251(16);5087-94. PMID: 821948


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.