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MetaCyc Compound: H2

Synonyms: hydrogen, hydrogen molecule

Chemical Formula: H2

Molecular Weight: 2.016 Daltons

Monoisotopic Molecular Weight: 2.0156500642 Daltons

H<SUB>2</SUB> compound structure

SMILES: [HH]

InChI: InChI=1S/H2/h1H

InChIKey: InChIKey=UFHFLCQGNIYNRP-UHFFFAOYSA-N

Unification Links: CAS:1333-74-0 , ChEBI:18276 , ChemSpider:762 , HMDB:HMDB01362 , IAF1260:34488 , KEGG:C00282 , MetaboLights:MTBLC18276 , PubChem:783

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): 24.752243 Inferred by computational analysis [Latendresse13]

Reactions known to consume the compound:

coenzyme B/coenzyme M regeneration :
methanophenazine + H2 → dihydromethanophenazine

hydrogen to dimethyl sulfoxide electron transfer , hydrogen to fumarate electron transfer , hydrogen to trimethylamine N-oxide electron transfer :
a menaquinone[inner membrane] + 2 H+ + H2[periplasmic space] → a menaquinol[inner membrane] + 2 H+[periplasmic space]

sulfur reduction I :
S0 + H2 → hydrogen sulfide

sulfur reduction II (via polysulfide) :
(sulfide)n + H2 → hydrogen sulfide + (sulfide)n-1

Not in pathways:
2 H2 + oxygen → 2 H2O

Reactions known to produce the compound:

hydrogen production I :
2 an oxidized ferredoxin + NAD+ + 2 H2 ← 2 a reduced ferredoxin + NADH + 3 H+

mixed acid fermentation :
formate + H+ → CO2 + H2

nitrogen fixation I (ferredoxin) :
8 reduced ferredoxins + N2 + 16 ATP + 16 H2O → 8 oxidized ferredoxins + 2 ammonium + 16 ADP + 16 phosphate + H2 + 6 H+

nitrogen fixation II (flavodoxin) :
4 a reduced flavodoxin + N2 + 16 ATP + 16 H2O → 4 an oxidized flavodoxin + 2 ammonium + 16 ADP + 16 phosphate + H2 + 14 H+

Reactions known to both consume and produce the compound:

hydrogen oxidation I (aerobic) , hydrogen production VI :
an oxidized unknown electron acceptor + H2 ↔ an reduced unknown electron acceptor

hydrogen oxidation II (aerobic, NAD) , hydrogen production II :
NAD+ + H2 ↔ NADH + H+

hydrogen oxidation III (anaerobic, NADP) , hydrogen production IV :
NADP+ + H2 ↔ NADPH + H+

hydrogen production III , hydrogen production VIII , L-glutamate degradation VII (to butanoate) , superpathway of fermentation (Chlamydomonas reinhardtii) :
2 an oxidized ferredoxin + H2 ↔ 2 a reduced ferredoxin + 2 H+

hydrogen production V :
a reduced hydrogenase 3 + H+ ↔ an oxidized hydrogenase 3 + H2

methanogenesis from H2 and CO2 :
5,10-methenyltetrahydromethanopterin + H2 ↔ 5,10-methylene-tetrahydromethanopterin + H+

Not in pathways:
NAD(P)+ + H2 ↔ NAD(P)H + H+

In Reactions of unknown directionality:

Not in pathways:
carbon monoxide + H2O = CO2 + H2
an oxidized coenzyme F420 + H2 = a reduced coenzyme F420
a menaquinone + H2 = a menaquinol
an oxidized cytochrome c3 + 2 H2 = a reduced cytochrome c3 + 2 H+

In Redox half-reactions:
2 H+[out] + 2 e-[membrane]H2[out] ,
2 H+[in] + 2 e-[membrane]H2[in]


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Aug 4, 2015, biocyc11.