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MetaCyc Compound: potassium chloride

Superclasses: a salt an inorganic salt
an inorganic compound an inorganic salt

Chemical Formula: KCl

Molecular Weight: 74.551 Daltons

Salt Constituents: chloride , K+

Unification Links: ChEBI:32588 , ChemSpider:4707 , DrugBank:DB00761 , KEGG:D02060 , PubChem:4873

Enzymes activated by potassium chloride, sorted by the type of activation, are:

Activator (Mechanism unknown) of: 1-phosphofructokinase [VeigadaCunha00] , dihydrofolate reductase [Wilquet98] , D-xylose dehydrogenase [Johnsen04]

Enzymes inhibited by potassium chloride, sorted by the type of inhibition, are:

Inhibitor (Competitive) of: 3-carboxymuconate cycloisomerase [Williams92] , pyruvate decarboxylase [Lee85]

Inhibitor (Mechanism unknown) of: holo-[acyl-carrier-protein] synthase [Elovson68] , fructose-1,6-bisphosphatase [Brown09] , polyphosphate kinase [Ahn90] , phosphoenolpyruvate carboxylase [Patel04] , Ins(1,3,4,5,6)P5 2-kinase [Phillippy94] , UDP-D-glucuronic acid 4-epimerase [Gu04a] , dimethylglycine-betaine methyltransferase [Waditee03] , UDP-D-apiose synthase [Molhoj03] , UDP-D-xylose synthase [Molhoj03] , ADP-dependent phosphofructokinase [Tuininga99] , uroporphyrinogen III cosynthetase [Stevens68]

Inhibitor (Other types) of: UDP phosphatase [Klohs73]


References

Ahn90: Ahn K, Kornberg A (1990). "Polyphosphate kinase from Escherichia coli. Purification and demonstration of a phosphoenzyme intermediate." J Biol Chem 1990;265(20);11734-9. PMID: 2164013

Brown09: Brown G, Singer A, Lunin VV, Proudfoot M, Skarina T, Flick R, Kochinyan S, Sanishvili R, Joachimiak A, Edwards AM, Savchenko A, Yakunin AF (2009). "Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli." J Biol Chem 284(6);3784-92. PMID: 19073594

Elovson68: Elovson J, Vagelos PR (1968). "Acyl carrier protein. X. Acyl carrier protein synthetase." J Biol Chem 1968;243(13);3603-11. PMID: 4872726

Gu04a: Gu X, Bar-Peled M (2004). "The biosynthesis of UDP-galacturonic acid in plants. Functional cloning and characterization of Arabidopsis UDP-D-glucuronic acid 4-epimerase." Plant Physiol 136(4);4256-64. PMID: 15563616

Johnsen04: Johnsen U, Schonheit P (2004). "Novel xylose dehydrogenase in the halophilic archaeon Haloarcula marismortui." J Bacteriol 186(18);6198-207. PMID: 15342590

Klohs73: Klohs WD, Goff CW (1973). "A characterization of nucleoside diphosphatase in the onion root tip." J Histochem Cytochem 21(5);417-25. PMID: 4353821

Lee85: Lee T.C., Langston-Unkefer P.J. "Pyruvate decarboxylase from Zea mays L. I. Purification and partial characterization from mature kernels and anaerobically treated roots." Plant Physiol. (1985) 79:242-247.

Molhoj03: Molhoj M, Verma R, Reiter WD (2003). "The biosynthesis of the branched-chain sugar d-apiose in plants: functional cloning and characterization of a UDP-d-apiose/UDP-d-xylose synthase from Arabidopsis." Plant J 35(6);693-703. PMID: 12969423

Patel04: Patel HM, Kraszewski JL, Mukhopadhyay B (2004). "The phosphoenolpyruvate carboxylase from Methanothermobacter thermautotrophicus has a novel structure." J Bacteriol 186(15);5129-37. PMID: 15262949

Phillippy94: Phillippy BQ, Ullah AH, Ehrlich KC (1994). "Purification and some properties of inositol 1,3,4,5,6-Pentakisphosphate 2-kinase from immature soybean seeds." J Biol Chem 269(45);28393-9. PMID: 7961779

Stevens68: Stevens E, Frydman B (1968). "Isolation and properties of wheat germ uroporphyrinogen 3 cosynthetase." Biochim Biophys Acta 151(2);429-37. PMID: 5636375

Tuininga99: Tuininga JE, Verhees CH, van der Oost J, Kengen SW, Stams AJ, de Vos WM (1999). "Molecular and biochemical characterization of the ADP-dependent phosphofructokinase from the hyperthermophilic archaeon Pyrococcus furiosus." J Biol Chem 274(30);21023-8. PMID: 10409652

VeigadaCunha00: Veiga-da-Cunha M, Hoyoux A, Van Schaftingen E, Houyoux A (2000). "Overexpression and purification of fructose-1-phosphate kinase from Escherichia coli: application to the assay of fructose 1-phosphate." Protein Expr Purif 19(1);48-52. PMID: 10833389

Waditee03: Waditee R, Tanaka Y, Aoki K, Hibino T, Jikuya H, Takano J, Takabe T, Takabe T (2003). "Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica." J Biol Chem 278(7);4932-42. PMID: 12466265

Williams92: Williams SE, Woolridge EM, Ransom SC, Landro JA, Babbitt PC, Kozarich JW (1992). "3-Carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida is homologous to the class II fumarase family: a new reaction in the evolution of a mechanistic motif." Biochemistry 31(40);9768-76. PMID: 1390752

Wilquet98: Wilquet V, Gaspar JA, van de Lande M, Van de Casteele M, Legrain C, Meiering EM, Glansdorff N (1998). "Purification and characterization of recombinant Thermotoga maritima dihydrofolate reductase." Eur J Biochem 1998;255(3);628-37. PMID: 9738902


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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