MetaCyc Compound: MgCl2

Synonyms: magnesium chloride

Superclasses: a salt an inorganic salt
an inorganic compound an inorganic salt

Chemical Formula: MgCl2

Molecular Weight: 95.211 Daltons

Salt Constituents: Mg2+ , chloride

Unification Links: ChEBI:6636 , ChemSpider:22987 , KEGG:C07755 , PubChem:24584

Enzymes activated by MgCl2, sorted by the type of activation, are:

Activator (Mechanism unknown) of: 8-hydroxykaempferol 8-O-methyltransferase [Jay85] , gossypetin 8-O-methyltransferase [Jay85] , SAM: anol-O-methyltransferase [Kemmerer96] , D-xylose dehydrogenase [Johnsen04] , phosphate acetyltransferase [Bock99]

Enzymes inhibited by MgCl2, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: D-alanyl-D-alanine carboxypeptidase [Amanuma80] , homogalacturonan methyltransferase [Goubet99] , UDP-D-apiose synthase [Molhoj03] , UDP-D-xylose synthase [Molhoj03] , uroporphyrinogen III cosynthetase [Stevens68]

This compound has been characterized as a cofactor or prosthetic group of the following enzymes: (+)-δ-cadinene synthase , (+)-δ-cadinene synthase


Amanuma80: Amanuma H, Strominger JL (1980). "Purification and properties of penicillin-binding proteins 5 and 6 from Escherichia coli membranes." J Biol Chem 255(23);11173-80. PMID: 7002918

Bock99: Bock AK, Glasemacher J, Schmidt R, Schonheit P (1999). "Purification and characterization of two extremely thermostable enzymes, phosphate acetyltransferase and acetate kinase, from the hyperthermophilic eubacterium Thermotoga maritima." J Bacteriol 1999;181(6);1861-7. PMID: 10074080

Goubet99: Goubet F, Mohnen D (1999). "Solubilization and partial characterization of homogalacturonan-methyltransferase from microsomal membranes of suspension-cultured tobacco cells." Plant Physiol 121(1);281-90. PMID: 10482684

Jay85: Jay M, De Luca V, Ibrahim RK (1985). "Purification, properties and kinetic mechanism of flavonol 8-O-methyltransferase from Lotus corniculatus L." Eur J Biochem 153(2);321-5. PMID: 4076180

Johnsen04: Johnsen U, Schonheit P (2004). "Novel xylose dehydrogenase in the halophilic archaeon Haloarcula marismortui." J Bacteriol 186(18);6198-207. PMID: 15342590

Kemmerer96: Kemmerer, B, Reichling, J (1996). "S-adenosyl-L-methionine: Anol-o-methyltransferase activtity in organ cultures of Pimpinella anisum." Phytochemistry, 42, 397-403.

Molhoj03: Molhoj M, Verma R, Reiter WD (2003). "The biosynthesis of the branched-chain sugar d-apiose in plants: functional cloning and characterization of a UDP-d-apiose/UDP-d-xylose synthase from Arabidopsis." Plant J 35(6);693-703. PMID: 12969423

Stevens68: Stevens E, Frydman B (1968). "Isolation and properties of wheat germ uroporphyrinogen 3 cosynthetase." Biochim Biophys Acta 151(2);429-37. PMID: 5636375

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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