Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Compound: Zn2+

Synonyms: Zn, Zinc, Zn+2, Zn++, zinc ion, Zn(II)

Superclasses: an ion a cation

Component of:
zinc sulfate heptahydrate
zinc sulfate

Chemical Formula: Zn

Molecular Weight: 65.38 Daltons

Monoisotopic Molecular Weight: 65.9447966642 Daltons

SMILES: [Zn++]

InChI: InChI=1S/Zn/q+2

InChIKey: InChIKey=PTFCDOFLOPIGGS-UHFFFAOYSA-N

Unification Links: CAS:7440-66-6 , ChEBI:29105 , ChemSpider:29723 , HMDB:HMDB01303 , IAF1260:33614 , KEGG:C00038 , MetaboLights:MTBLC29105 , PubChem:32051

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -1.2482376 Inferred by computational analysis [Latendresse13]

In Transport reactions:
Zn2+[cytosol] + ATP + H2O → Zn2+[periplasmic space] + ADP + phosphate + H+ ,
Zn2+[cytosol] + H+[periplasmic space]Zn2+[periplasmic space] + H+[cytosol] ,
Zn2+[periplasmic space]Zn2+[cytosol] ,
Zn2+[periplasmic space] + ATP + H2O → Zn2+[cytosol] + ADP + phosphate + H+

Enzymes activated by Zn2+, sorted by the type of activation, are:

Activator (Allosteric) of: phosphoglycerol geranylgeranyltransferase [Chen93a] , glycerol-1-phosphate dehydrogenase [Daiyasu02] , (1S,4R)-1-hydroxy-2-oxolimonene monooxygenase [Van00] , succinate semialdehyde reductase [Berg07] , 6-pyruvoyl tetrahydrobiopterin synthase [Burgisser95] , methylated MtsB protein:coenzyme M methyltransferase [Tallant01] , dimethylsulfide:MtsB protein methyltransferase [Tallant01] , cytosolic leucyl aminopeptidase [Taylor93] , inositol-1-phosphate synthase [Chen00] , [Cys-Gly]-S-conjugate dipeptidase [Taylor93] , mycothiol S-conjugate amidase [Steffek03] , α-acetolactate decarboxylase [Phalip94] , glyoxalase I [Marmstal79] , cysteinylglycine dipeptidase [Taylor93] , respiratory arsenate reductase [Krafft98] , glyoxalase II (cytoplasmic) [Bito99] , mycothiol S-conjugate amidase [Steffek03] , glyoxalase I [SaintJean98]

Activator (Mechanism unknown) of: D-mannonate oxidoreductase [Portalier72] , Ap4A synthetase [Plateau82, Charlier87] , Ap3A synthetase [Plateau82] , nonspecific dipeptidase [Schroeder94] , GTPase [BlabyHaas12] , 3-benzyl-3,6 -bis(cysteinylglycine)-6-(hydroxymethyl)-diketopiperazine dipeptidase [Scharf13] , caffeoyl-CoA 3-O-methyltransferase [Ibdah03] , caffeoylglucose 3-O-methyltransferase [Ibdah03] , caffeate 3-O-methyltransferase [Ibdah03] , quercetin 3'-O-methyltransferase [Ibdah03] , gossypetin 8-methyl ester 3'-O-methyltransferase [Ibdah03] , gossypetin 8-O-methyltransferase [Ibdah03] , laricitrin 5'-O-methyltransferase [Ibdah03] , myricetin 3'-O-methyltransferase [Ibdah03] , patuletin 3'-O-methyltransferase [Ibdah03] , quercetagetin 6O-methyltransferase [Ibdah03] , NADH kinase [Kawai01] , NAD(+) kinase [Kawai01] , pyridoxal kinase [Lum02] , D-xylulose-5-phosphate cytidylyltransferase [Wang12b] , trehalose-6-phosphate synthase [Chaudhuri09] , homophytochelatin synthase [Loscos06] , homophytochelatin synthase [Oven02] , GA4 carboxyl methyltransferase [Varbanova07] , indole-3-acetate carboxyl methyltransferase [Zhao07] , streptomycin 6-kinase [Sugiyama83] , acetylpyruvate hydrolase [Davey75] , UDP-N-acetylglucosamine pyrophosphorylase [Szumilo96] , caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase [Fujiwara97] , caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase [Fujiwara97] , molybdopterin molybdotransferase [Llamas06]

Enzymes inhibited by Zn2+, sorted by the type of inhibition, are:

Inhibitor (Competitive) of: ornithine carbamoyltransferase [Comment 1] , ornithine carbamoyltransferase [Comment 2] , cytosine deaminase [Porter93, Comment 3] , geraniol dehydrogenase [Iijima06] , tyrosine 3-monooxygenase [Haavik91] , ornithine carbamoyltransferase [Comment 4] , glycine formimidoyltransferase [Uyeda65]

Inhibitor (Noncompetitive) of: L-alanine dehydrogenase [Yoshida70]

Inhibitor (Allosteric) of: diguanylate cyclase [Zahringer13] , 4-hydroxy-2-oxovalerate aldolase [Powlowski93]

Inhibitor (Mechanism unknown) of: tetrahydrodipicolinate succinylase [Simms84] , imidazoleglycerol-phosphate dehydratase [Brady73] , selenide, water dikinase [Veres94, Kim93, Kim94] , fructoselysine 6-phosphate deglycase [Wiame02] , fructoselysine 3-epimerase [Wiame04] , betaine aldehyde dehydrogenase [Falkenberg90] , UDP-3-O-acyl-N-acetylglucosamine deacetylase [Jackman99] , 3-deoxy-D-manno-octulosonate 8-phosphate synthase [Ray80] , D-arabinose 5-phosphate isomerase [Meredith05] , methylmalonyl-CoA mutase [Bobik03] , glycolate oxidase [Lord72] , deoxyribose 1,5-phosphomutase [HammerJespersen70] , α-galactosidase [Burstein71] , D-galacturonate isomerase [Ashwell60] , D-glucuronate isomerase [Ashwell60] , N-acetylglutamate synthase [Marvil77] , N-acetylglutamylphosphate reductase [Vogel74] , acetylornithine deacetylase [Vogel74b, JavidMajd00] , adenosylmethionine decarboxylase [Lu07] , adenine phosphoribosyltransferase [Hochstadt78a] , hypoxanthine phosphoribosyltransferase [Hochstadt78] , inosine kinase [Mori95] , guanosine kinase [Mori95] , adenylosuccinate synthetase [Kang95] , S-formylglutathione hydrolase [Gonzalez06] , phenylalanyl-tRNA synthetase [Mayaux81] , glycolaldehyde dehydrogenase [Baldoma87] , argininosuccinate lyase [Vogel74] , malate dehydrogenase [Wang11b] , glutamate decarboxylase A [Helmward89] , glutamate decarboxylase B [Helmward89] , cytochrome bo terminal oxidase [Helmward89, Kita86, Kita84] , taurine dioxygenase [Eichhorn97] , L-1,2-propanediol oxidoreductase [Obradors98, Montella05] , glycolaldehyde reductase [Obradors98] , L-serine deaminase [Newman80] , methylglyoxal reductase (NADPH-dependent) [Saikusa87] , S-formylglutathione hydrolase [Gonzalez06] , glyoxalase [Subedi11] , glycogen phosphorylase [Chen68, Chen68a] , D-aminopropanol dehydrogenase [Kelley84, Campbell78] , non-heme bacterial ferritin [Treffry98a] , pyridine nucleotide transhydrogenase [Cao11] , dipeptidyl carboxypeptidase [Henrich93] , fumarase A [Xu12] , lysyl-tRNA synthetase [Plateau82, Charlier87] , N-acetylmuramoyl-L-alanine amidase [vanHeijenoort75] , 7-α-hydroxysteroid dehydrogenase [Yoshimoto91] , polyphosphate kinase [Haeusler92] , GTPase [Sydor13] , 2',3'-cyclic nucleotide 2'-phosphodiesterase [ANRAKU64] , 3'-nucleotidase [ANRAKU64] , amylomaltase [Wiesmeyer60] , cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase [Liu09] , didemethylasteriquinone D prenyltransferase [Schneider08] , 1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) [Funa05] , 5'-demethoxy-6-methoxypodophyllotoxin 7-O-glucosyltransferase [Berim08] , 6-methoxypodophyllotoxin 7-O-glucosyltransferase [Berim08] , podophyllotoxin 7-O-glucosyltransferase [Berim08] , paxilline dimethylallyl diphosphate transferase [Liu14] , cellobiose 2-epimerase [Taguchi08] , synephrine dehydratase [Manne86] , glycerophosphocholine cholinephosphodiesterase [Sugimori13] , acyl-CoA:lyso-phosphatidate acyltransferase [Chen07a] , acyl-CoA:lyso-phosphatidylcholine acyltransferase [Chen07a] , acyl-CoA:lyso-phosphatidylethanolamine acyltransferase [Chen07a] , lyso-phosphatidylcholine acyltransferase [Richard98] , oleoyl-CoA: lysophosphatidate acyltransferase [Rajakumari10] , triacylglycerol lipase [Rajakumari10] , oleoyl-CoA:lysophosphatidate acyltransferase [Rajakumari10] , oleoyl-CoA:lysophosphatidylethanolamine acyltransferase [Rajakumari10] , phosphoribosylpyrophosphate amidotransferase [Satyanarayana71] , NADH kinase [Shi05a] , NAD(+) kinase [Shi05a] , uridine-5'-monophosphate:2-oxoglutarate dioxygenase [Yang11] , pyridoxamine 5'-phosphate oxidase [Tsuge82] , pyridoxine 5'-phosphate oxidase II [Tsuge82] , quercetin 3-O-β-D-galactoside-2"-O-glucosyltransferase [Vogt95] , kaempferol 3-O-β-D-galactoside-2"-O-glucosyltransferase [Vogt95] , kaempferide 3-O-glucosyltransferase (F3GT2) [Ishikura94] , kaempferide 3-O-glucosyltransferase (F3GT1) [Ishikura94] , 3,6,7,2',4'-pentamethylquercetagetin 3'-O-glucosyltransferase [Bajaj83] , 2'-hydroxy 3,6,7,4'-tetramethylquercetagetin 3'-O-glucosyltransferase [Bajaj83] , 3,6,7,4'-tetramethylquercetagetin 3'-O-glucosyltransferase [Bajaj83] , 3,7,4'-trimethylquercetagetin 3'-O-glucosyltransferase [Bajaj83] , 2'-hydroxy 3,7,3',4'-tetramethylquercetin 2'-O-glucosyltransferase [Bajaj83] , 2'-hydroxy 3,7,4'-trimethylquercetin 2'-O-glucosyltransferase [Bajaj83] , 2'-hydroxy 3,6,7,4'-tetramethylquercetagetin 3'-O-glucoside 2'-O-methyltransferase [Khouri86] , 3,7,4'trimethylquercetin 2'-O-glucoside 3'-O-methyltransferase [Khouri86] , 3-O-methylquercetin 7-O-methyltransferase [Khouri88] , kaempferol 3-O-glucosyltransferase [Owens] , quercetin 3-O-glucosyltransferase [Owens] , myricetin 3-O-glucosyltransferase [Owens] , 7'-O-demethylcephaeline 7'-O-methyltransferase [Cheong11] , omega-hydroxypalmitate O-feruloyl transferase [Rautengarten12] , thiobenzoate-S-methyltransferase , phosphoenolpyruvate phosphatase [Tran10] , phosphoenolpyruvate phosphatase [Veljanovski06] , 2-hydroxy-1,4-benzoquinone reductase [Takenaka11] , anol synthase [Koeduka09] , eugenol synthase [Koeduka09] , SAM:t-anol O-methyltransferase [Koeduka09] , isoeugenol synthase [Koeduka06] , eugenol synthase [Koeduka06] , (+)-germacrene D synthase [Picaud06] , UDPG:ginsenoside Rd glucosyltransferase [Yue05] , o-dihydric phenol O-methyltransferase (para-methylation) [Tsang79] , esculetin 6-O-methyltransferase (meta-methylation) [Tsang79] , fumigaclavine A dimethylallyltransferase [Unsold06] , esculetin 7-O-glucosyltransferase [Taguchi00] , UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase [Yokoyama08] , 4-oxalocrotonate tautomerase [Orii06] , 2-hydroxymuconate 6-semialdehyde dehydrogenase [Orii06] , 2-amino-5-carboxymuconic 6-semialdehyde deaminase [Orii04] , 6-hydroxy-3-succinoyl-pyridine hydroxylase [Tang11] , isoprimeverose α-xylosidase [Moracci00] , pullulanase [Dong97] , L-rhamnono-γ-lactonase [Watanabe08] , NAD+-dependent L-rhamnofuranose 1-dehydrogenase [Rigo76] , glucosylglycerate synthase [Fernandes10] , N-benzylformamide deformylase [Fukatsu04] , chondroitin sulfate A endolyase [Hamai97] , chondroitin 4-sulfate exolyase [Hamai97] , dermatan sulfate exolyase [Hamai97] , farnesoic acid carboxyl methyltransferase [Yang06a] , 7-methylxanthine demethylase [Gluck88] , theobromine N3-demethylase [Asano94, Asano93] , pectate lyase [Tardy97] , pectate lyase [Tardy97] , pectate lyase [Tardy97] , GA9 carboxyl methyltransferase [Varbanova07] , oxidized polyvinylalcohol hydrolase [Klomklang05] , peptidoglycan-N-acetylglucosamine deacetylase [Psylinakis05] , L-galactono-γ-lactone dehydrogenase [Shigeoka79] , phosphatidylinositol synthase [Antonsson94] , phenylacetyl-coenzyme A:glycine N-acyltransferase [Nandi79] , β-alanine amide amidase [Komeda04] , L-proline amide hydrolase [Komeda04a] , 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase [Pucci07] , 3-hydroxyanthranilate 3,4-dioxygenase [Calderone02] , methyl indole-3-acetate methylesterase , 3-dehydroshikimate dehydratase [Pfleger08] , putrescine N-methyltransferase [Hibi92] , dihydrocoumarin hydrolase [Kosuge62] , hydroxyproline 2-epimerase [Adams64] , 4-oxalomesaconate hydratase [Maruyama85] , feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase [Yu99] , cytidine 5'-monophosphate N-acetylneuraminate synthetase [RodriguezAparic92] , ε-N-trimethyllysine hydroxylase [Sachan80] , iminodiacetate dehydrogenase [Uetz93] , 27-O-demethyl-rifamycin SV methyltransferase [Xu03] , kanosamine 6-kinase [Arakawa02] , sterigmatocystin O-methyltransferase [Liu99d] , NAD-dependent ATP dehydrogenase [Rubio98] , carboxynorspermidine decarboxylase [Nakao90] , desoxyhemigossypol-6-O-methyltransferase [Liu99e] , (R)-citramalyl-CoA lyase [Friedmann07] , triazine hydrolase [Topp00] , deacetoxycephalosporin C hydroxylase [Baker91] , deacetoxycephalosporin C hydroxylase [Dotzlaf87] , deacetoxycephalosporin C synthase [Dotzlaf87] , isopenicillin N epimerase [Laiz90] , isopenicillin N synthase [Castro88] , 3-hydroxyanthranilate 3,4-dioxygenase [Muraki03] , succinate semialdehyde dehydrogenase [Chambliss92] , S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase [Sato94] , 2-pyrone-4,6-dicarboxylate hydrolase [Kersten82] , UDPG:nicotinate N-glucosyltransferase [Upmeier88] , histidinol dehydrogenase [Nagai91] , myo-inositol-hexakisphosphate 4-phosphohydrolase [Greiner02] , porphobilinogen deaminase [Jones94] , myo-inositol-hexakisphosphate 3-phosphohydrolase [Greiner02] , glycerol-3-phosphate cytidylyltransferase [Park93a] , benzoyl-coenzyme A:benzyl alcohol benzoyltransferase [DAuria02] , sucrose synthase [Elling95] , trehalose synthase [Nishimoto96] , ornithine carbamoyltransferase [Morizono97a] , 3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase [Morishige00] , glycerol dehydrogenase [Daniel95] , maltooligosyl-trehalose trehalohydrolase , lysine N6-acetyltransferase [Bode93] , L-lactate dehydrogenase [Wrba90] , L-carnitine dehydrogenase [Mori88] , adenylosuccinate synthetase [Ryzhova98] , feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase [Hohlfeld95] , arginine deiminase [Hill67] , trehalose phosphorylase [Kizawa95] , kynurenine formamidase [Brown86] , L-carnitine dehydrogenase [Hanschmann96] , phosphoribosylpyrophosphate amidotransferase [Satyanarayana71] , S-adenosyl-L-methionine:isoeugenol-O-methyltransferase [Wang98e] , S-adenosyl-L-methionine:eugenol-O-methyltransferase [Wang98e] , kynurenine formamidase [Brown86] , trehalose synthase [Nishimoto96a] , trehalose phosphorylase [Saito98] , arogenate dehydratase [Jung86] , DL-methylmalonyl-CoA racemase [Stabler85] , DIMBOA-glucoside 4-O-methyltransferase [Oikawa02] , glutathione peroxidase [Takahashi87] , sulfur:ferric ion oxidoreductase [Sugio89a] , myo-inositol-hexakisphosphate phosphohydrolase [Greiner01] , myo-inositol-hexakisphosphate 3-phosphohydrolase [Greiner02] , sucrose-phosphate phosphatase [Lunn00] , pectin methyltransferase [Ishikawa00] , 2-pyrone-4,6-dicarboxylate hydrolase [Maruyama83] , 2-pyrone-4,6-dicarboxylate hydrolase [Masai99] , maltooligosyl-trehalose trehalohydrolase [Nakada95] , UDP-glucose:phenylacetothiohydroximate glucosyltransferase [Reed93a] , galactokinase [Dey83] , naringenin 7-O-methyltransferase [Rakwal00] , 4-coumaroyl-CoA:pelargonidin-3-O-β-D-glucoside-6''-O-acyltransferase [Fujiwara98] , isoliquiritigenin 4'-glucosyltransferase [Stich94] , butein 4'-glucosyltransferase [Stich94] , butein 4'-glucosyltransferase [Halbwirth97] , sulfuretin 4'-glucosyltransferase [Halbwirth97] , eriodictyol: 2-oxoglutarate oxygen oxidoreductase [Britsch90] , naringenin,2-oxoglutarate oxygen oxidoreductase [Britsch90] , guanine deaminase [Negishi94] , guanosine deaminase [Negishi94] , tyrosine 3-monooxygenase [Yamamoto01] , caffeoyl-CoA:pelargonidin-3-O-β-D-glucoside-6''-O-acyltransferase [Fujiwara98] , D-galactonate dehydratase [Szumilo81] , 4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase [Fujiwara98] , δ-aminovaleramidase [Reitz70] , Δ1-piperideine-2-carboxylate reductase [Payton82] , 4-coumaroyl-CoA:cyanidin-3-O-β-D-glucoside-6''-O-acyltransferase [Fujiwara98] , L-sorbosone dehydrogenase [Asakura99] , phosphohexose isomerase [Sangwan90] , 2-coumarate O-β-glucosyltransferase [Kleinhofs67] , caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase [Fujiwara98] , anthocyanin 5-O-glucoside-4'''-O-malonyltransferase [Suzuki04a] , 3-keto-5-aminohexanoate cleavage enzyme [Yorifuji77] , acetyl-CoA:salutaridinol-7-O-acetyltransferase [Lenz95] , diketodeoxyinositol hydrolase [Berman66] , L-asparaginase [Raha90] , formimidoyltetrahydrofolate cyclodeaminase [Uyeda67] , L-lysine α-oxidase [Weber94a] , α-D-galactosyl-(1-3)-1D-myo-inositol:raffinose galactosyltransferase [Peterbauer98] , flavone synthase [Britsch90] , α-D-galactosyl-(1-3)-1D-myo-inositol:raffinose galactosyltransferase [Gaudreault81] , 3,4-dihydroxyphenylacetate dioxygenase [Gibello94]

Inhibitor (Other types) of: D-arabinose 5-phosphate isomerase [Lim66, Meredith03, Airoldi10] , androsta-1,4-diene-3,17-dione 9α-hydroxylase [Petrusma09] , xylan 1,3-β-xylosidase [Umemoto08] , acetophenone carboxylase [Jobst10] , geranylgeranyl diphosphate diphosphatase [Nualkaew06] , (-)-dihydrocarvone monooxygenase , (1S,4R)-iso-dihydrocarvone monooxygenase [Van00] , (1R,4S)-iso-dihydrocarvone monooxygenase [Van00] , (1R,4R)-dihydrocarvone monooxygenase [Van00] , (1R,4S)-1-hydroxy-2-oxolimonene monooxygenase [Van00] , cis-aconitate decarboxylase [Bentley57] , D-sorbitol dehydrogenase [Yamaguchi94] , L-allo-threonine aldolase [Kataoka97] , raffinose synthase [Lehle73] , β-ketoadipyl CoA thiolase [Kaschabek02]

This compound has been characterized as a cofactor or prosthetic group of the following enzymes: mannose-6-phosphate isomerase , L-galactonate oxidoreductase , N-succinyl-L-diaminopimelate desuccinylase , isopentenyl diphosphate isomerase , dihydroorotase , anhydro-N-acetylmuramoyl-L-alanine amidase , N-acetylglucosamine-6-phosphate deacetylase , 3-demethylubiquinone-8 3-O-methyltransferase , rhamnulose-1-phosphate aldolase , L-ribulose 5-phosphate 4-epimerase , deoxycytidine deaminase , cytidine deaminase , tRNA-guanine transglycosylase , acyl carrier protein phosphodiesterase , D-ribulose-phosphate aldolase , L-fuculose-phosphate aldolase , D-glucuronate isomerase , porphobilinogen synthase , glutamyl-tRNA synthetase , deoxyuridine triphosphatase , acetylornithine deacetylase , cobalamin-independent homocysteine transmethylase , methionine synthase , GTP cyclohydrolase , threonine dehydrogenase , guanine deaminase , 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent , allantoinase , formaldehyde dehydrogenase , cysteinyl-tRNA synthetase , isoleucyl-tRNA synthetase , alanyl-tRNA synthetase , threonyl-tRNA synthetase , methionyl-tRNA synthetase , 3-dehydroquinate synthase , fructose bisphosphate aldolase , UDP-glucose:α-D-galactose-1-phosphate uridylyltransferase , carbonic anhydrase , glyoxalase II , isoaspartyl dipeptidase , 23S rRNA m1G745 methyltransferase , 5'-ribonucleotidase , UDP-sugar hydrolase , tRNA adenosine deaminase , ATP-dependent zinc metalloendoprotease , aldehyde reductase , diacylglycerol kinase , aminopeptidase , ribonucleoside-triphosphate reductase , alkaline phosphatase , Cys-Gly metallodipeptidase , shikimate dehydrogenase , linuron hydrolase , linuron hydrolase , 8-hydroxygeraniol dehydrogenase , D-serine ammonia-lyase , carbonyl sulfide hydrolase , carbon disulfide hydrolase , CysO-cysteine hydrolase , 2,4-didehydro-inositol hydratase , L-iditol dehydrogenase , D-xylitol dehydrogenase , D-sorbitol dehydrogenase , dCMP deaminase , cytidine deaminase , 2'-deoxycytidine deaminase , deoxycytidylate deaminase , deoxycytidylate deaminase , cytidine deaminase , cytosine deaminase , 5-fluorocytosine deaminase , deoxycytidine deaminase , aminoacylase , aspartodeacetylase , aspartoacylase , 2-deoxy-scyllo-inosamine dehydrogenase , methanol:MtaC protein Co-methyltransferase , chitin deacetylase , phosphoenolpyruvate mutase , phosphonoacetate hydrolase , mitochondrial-processing peptidase , neoagarobiose 1,3-α-3,6-anhydro-L-galactosidase , cytidine deaminase , 10-hydroxygeranial oxidoreductase , 10-oxogeraniol oxidoreductase , 10-oxogeraniol dehydrogenase , NADPH-10-oxogeraniol dehydrogenase , 10-hydroxygeraniol oxidoreductase , 10-hydroxygeraniol oxidoreductase , carbon-monoxide dehydrogenase , cellulase , purine nucleosidase , N-acetylphosphatidylethanolamine-hydrolysing phospholipas , 2-keto-3-deoxy-L-rhamnoate aldolase , 7-cyano-7-deazaguanine synthase , S-adenosylhomocysteine deaminase , 5-methylthioadenosine deaminase , phophonoacetaldehyde reductase , acetophenone carboxylase , 4-oxalmesaconate hydratase , (2R)-2-hydroxy-2-methylbutanenitrile lyase , gelatinase A , prenyl protein-specific endoprotease , insulin-like growth factor binding protein-4 protease , N-benzylformamide deformylase , 8-oxoguanine deaminase , ethanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase , methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase , methanol dehydrogenase , D-alanyl-D-alanine carboxypeptidase , D-alanyl-D-alanine dipeptidase , dihydrouracil amidohydrolase , dihydrothymine amidohydrolase , β-alanine synthase , barbiturate amidohydrolase , hemoglobin metallopeptidase , Glu-Tyr endopeptidase , galactonolactonase , N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase , guanine deaminase , IMP 5'-nucleotidase , ammonia monooxygenase , acrylyl-CoA reductase , GTP cyclohydrolase , pseudolysin , carbonic anhydrase , (+)-4-chloromuconolactone hydrolase , trans-4-carboxymethylenebut-2-en-4-olide lactonohydrolase , histidinol phosphate phosphatase , acetylpolyamine amidohydrolase , (R,R)-butanediol dehydrogenase , methylenetetrahydrofolate reductase , biliverdin reductase , enamidase , triazine hydrolase , N-isopropylammelide isopropylaminohydrolase , (R)-2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming) , (S)-2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming) , acetone carboxylase , gluconolactonase , D-arabinose 1-dehydrogenase , 4-pyridoxolactonase , methylmalonyl-CoA carboxyltransferase , benzyl alcohol dehydrogenase , sulfate adenylyltransferase , isocitrate dehydrogenase , fructose-bisphosphate aldolase , sedoheptulose-1,7-bisphosphate aldolase , parathion hydrolase , MtaC protein: coenzyme M methyltransferase , glyceraldehyde-3-phosphate ferredoxin oxidoreductase , acetyl-CoA decarbonylase/synthase , β-ureidopropionase , butanol dehydrogenase , methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase , N-succinyl-L,L-diaminopimelate desuccinylase , butanol dehydrogenase , creatininase , carbon monoxide dehydrogenase , sulfate adenylyltransferase , phosphonoacetate hydrolase , betaine-homocysteine S-methyltransferase , S-hydroxymethyl-glutathione dehydrogenase , guanidinobutyrase , guanidinobutyrase , arginase


References

Adams64: Adams E, Norton IL (1964). "Purification and properties of inducible hydroxyproline 2-epimerase from Pseudomonas." J Biol Chem 239;1525-35. PMID: 14189888

Airoldi10: Airoldi C, Sommaruga S, Merlo S, Sperandeo P, Cipolla L, Polissi A, Nicotra F (2010). "Targeting bacterial membranes: NMR spectroscopy characterization of substrate recognition and binding requirements of D-arabinose-5-phosphate isomerase." Chemistry 16(6);1897-902. PMID: 20039350

ANRAKU64: ANRAKU Y (1964). "A NEW CYCLIC PHOSPHODIESTERASE HAVING A 3'-NUCLEOTIDASE ACTIVITY FROM ESCHERICHIA COLI B. I. PURIFICATION AND SOME PROPERTIES OF THE ENZYME." J Biol Chem 239;3412-9. PMID: 14245396

Antonsson94: Antonsson BE (1994). "Purification and characterization of phosphatidylinositol synthase from human placenta." Biochem J 297 ( Pt 3);517-22. PMID: 8110188

Arakawa02: Arakawa K, Muller R, Mahmud T, Yu TW, Floss HG (2002). "Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate." J Am Chem Soc 124(36);10644-5. PMID: 12207505

Asakura99: Asakura A, Hoshino T (1999). "Isolation and Characterization of a New Quinoprotein Dehydrogenase, L-Sorbose/L-Sorbosone Dehydrogenase." Biosci. Biotechnol. Biochem., 63 (1), 46-53.

Asano93: Asano Y, Komeda T, Yamada H (1993). "Microbial production of theobromine from caffeine." Biosci. Biotech. Biochem. 57 (8) , 1286-1289.

Asano94: Asano Y, Komeda T, Yamada H (1994). "Enzymes involved in theobromine production from caffeine by Pseudomonas putida No. 352." Biosci. Biotech. Biochem., 58 (12), 2303-2304.

Ashwell60: Ashwell G, Wahba AJ, Hickman J (1960). "Uronic acid metabolism in bacteria. I. Purification and properties of uronic acid isomerase in Escherichia coli." J Biol Chem. 235:1559-1565. PMID: 13794771

Bajaj83: Bajaj KL, de Luca V, Khouri H, Ibrahim RK (1983). "Purification and Properties of Flavonol-Ring B Glucosyltransferase from Chrysosplenium americanum." Plant Physiol 72(3);891-6. PMID: 16663104

Baker91: Baker BJ, Dotzlaf JE, Yeh WK (1991). "Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication." J Biol Chem 266(8);5087-93. PMID: 2002049

Baldoma87: Baldoma L, Aguilar J (1987). "Involvement of lactaldehyde dehydrogenase in several metabolic pathways of Escherichia coli K12." J Biol Chem 262(29);13991-6. PMID: 3308886

Bentley57: Bentley, R., Thiessen, C.P. (1957). "Biosynthesis of itaconic acid in Aspergillus terreus. III. The properties and reaction mechanism of cis-aconitic acid decarboxylase." J Biol Chem 226(2);703-20. PMID: 13438855

Berg07: Berg IA, Kockelkorn D, Buckel W, Fuchs G (2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea." Science 318(5857);1782-6. PMID: 18079405

Berim08: Berim A, Ebel R, Schneider B, Petersen M (2008). "UDP-glucose:(6-methoxy)podophyllotoxin 7-O-glucosyltransferase from suspension cultures of Linum nodiflorum." Phytochemistry 69(2);374-81. PMID: 17870138

Berman66: Berman T, Magasanik B (1966). "The pathway of myo-inositol degradation in Aerobacter aerogenes. Ring scission." J Biol Chem 1966;241(4);807-13. PMID: 5905123

Bito99: Bito A, Haider M, Briza P, Strasser P, Breitenbach M (1999). "Heterologous expression, purification, and kinetic comparison of the cytoplasmic and mitochondrial glyoxalase II enzymes, Glo2p and Glo4p, from Saccharomyces cerevisiae." Protein Expr Purif 17(3);456-64. PMID: 10600466

BlabyHaas12: Blaby-Haas CE, Flood JA, Crecy-Lagard Vd, Zamble DB (2012). "YeiR: a metal-binding GTPase from Escherichia coli involved in metal homeostasis." Metallomics 4(5);488-97. PMID: 22511334

Bobik03: Bobik TA, Rasche ME (2003). "HPLC assay for methylmalonyl-CoA epimerase." Anal Bioanal Chem 375(3);344-9. PMID: 12589497

Bode93: Bode R, Thurau AM, Schmidt H (1993). "Characterization of acetyl-CoA: L-lysine N6-acetyltransferase, which catalyses the first step of carbon catabolism from lysine in Saccharomyces cerevisiae." Arch Microbiol 160(5);397-400. PMID: 8257283

Brady73: Brady DR, Houston LL (1973). "Some properties of the catalytic sites of imidazoleglycerol phosphate dehydratase-histidinol phosphate phosphatase, a bifunctional enzyme from Salmonella typhimurium." J Biol Chem 1973;248(7);2588-92. PMID: 4349042

Britsch90: Britsch L (1990). "Purification and characterization of flavone synthase I, a 2-oxoglutarate-dependent desaturase." Arch Biochem Biophys 282(1);152-60. PMID: 2221917

Brown86: Brown D, Hitchcock MJ, Katz E (1986). "Purification and characterization of kynurenine formamidase activities from Streptomyces parvulus." Can J Microbiol 32(6);465-72. PMID: 2425918

Burgisser95: Burgisser DM, Thony B, Redweik U, Hess D, Heizmann CW, Huber R, Nar H (1995). "6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding." J Mol Biol 253(2);358-69. PMID: 7563095

Burstein71: Burstein C, Kepes A (1971). "The alpha-galactosidase from Escherichia coli K12." Biochim Biophys Acta 1971;230(1);52-63. PMID: 5543331

Calderone02: Calderone V, Trabucco M, Menin V, Negro A, Zanotti G (2002). "Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+." Biochim Biophys Acta 1596(2);283-92. PMID: 12007609

Campbell78: Campbell RL, Swain RR, Dekker EE (1978). "Purification, separation, and characterization of two molecular forms of D-1-amino-2-propanol:NAD+ oxidoreductase activity from extracts of Escherichia coli K-12." J Biol Chem 253(20);7282-8. PMID: 359547

Cao11: Cao Z, Song P, Xu Q, Su R, Zhu G (2011). "Overexpression and biochemical characterization of soluble pyridine nucleotide transhydrogenase from Escherichia coli." FEMS Microbiol Lett 320(1);9-14. PMID: 21545646

Castro88: Castro JM, Liras P, Laiz L, Cortes J, Martin JF (1988). "Purification and characterization of the isopenicillin N synthase of Streptomyces lactamdurans." J Gen Microbiol 134(1);133-41. PMID: 3183613

Chambliss92: Chambliss KL, Gibson KM (1992). "Succinic semialdehyde dehydrogenase from mammalian brain: subunit analysis using polyclonal antiserum." Int J Biochem 24(9);1493-9. PMID: 1426531

Charlier87: Charlier J, Sanchez R (1987). "Lysyl-tRNA synthetase from Escherichia coli K12. Chromatographic heterogeneity and the lysU-gene product." Biochem J 248(1);43-51. PMID: 3325036

Chaudhuri09: Chaudhuri P, Basu A, Sengupta S, Lahiri S, Dutta T, Ghosh AK (2009). "Studies on substrate specificity and activity regulating factors of trehalose-6-phosphate synthase of Saccharomyces cerevisiae." Biochim Biophys Acta 1790(5);368-74. PMID: 19289151

Chen00: Chen L, Zhou C, Yang H, Roberts MF (2000). "Inositol-1-phosphate synthase from Archaeoglobus fulgidus is a class II aldolase." Biochemistry 39(40);12415-23. PMID: 11015222

Chen07a: Chen Q, Kazachkov M, Zheng Z, Zou J (2007). "The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover." FEBS Lett 581(28);5511-6. PMID: 17996202

Chen68: Chen GS, Segel IH (1968). "Escherichia coli polyglucose phosphorylases." Arch Biochem Biophys 1968;127(1);164-74. PMID: 4878694

Chen68a: Chen GS, Segel IH (1968). "Purification and properties of glycogen phosphorylase from Escherichia coli." Arch Biochem Biophys 1968;127(1);175-86. PMID: 4878695

Chen93a: Chen A, Zhang D, Poulter CD (1993). "(S)-geranylgeranylglyceryl phosphate synthase. Purification and characterization of the first pathway-specific enzyme in archaebacterial membrane lipid biosynthesis." J Biol Chem 268(29);21701-5. PMID: 8408023

Cheong11: Cheong BE, Takemura T, Yoshimatsu K, Sato F (2011). "Molecular cloning of an O-methyltransferase from adventitious roots of Carapichea ipecacuanha." Biosci Biotechnol Biochem 75(1);107-13. PMID: 21228475

Daiyasu02: Daiyasu H, Hiroike T, Koga Y, Toh H (2002). "Analysis of membrane stereochemistry with homology modeling of sn-glycerol-1-phosphate dehydrogenase." Protein Eng 15(12);987-95. PMID: 12601138

Daniel95: Daniel R, Stuertz K, Gottschalk G (1995). "Biochemical and molecular characterization of the oxidative branch of glycerol utilization by Citrobacter freundii." J Bacteriol 177(15);4392-401. PMID: 7635824

DAuria02: D'Auria JC, Chen F, Pichersky E (2002). "Characterization of an acyltransferase capable of synthesizing benzylbenzoate and other volatile esters in flowers and damaged leaves of Clarkia breweri." Plant Physiol 130(1);466-76. PMID: 12226525

Davey75: Davey JF, Ribbons DW (1975). "Metabolism of resorcinylic compounds by bacteria. Purification and properties of acetylpyruvate hydrolase from Pseudomonas putida 01." J Biol Chem 1975;250(10);3826-30. PMID: 236305

Dey83: Dey PM (1983). "Galactokinase of Vicia faba seeds." Eur J Biochem 136(1);155-9. PMID: 6617655

Dong97: Dong G, Vieille C, Zeikus JG (1997). "Cloning, sequencing, and expression of the gene encoding amylopullulanase from Pyrococcus furiosus and biochemical characterization of the recombinant enzyme." Appl Environ Microbiol 63(9);3577-84. PMID: 9293009

Dotzlaf87: Dotzlaf JE, Yeh WK (1987). "Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremonium." J Bacteriol 169(4);1611-8. PMID: 3558321

Eichhorn97: Eichhorn E, van der Ploeg JR, Kertesz MA, Leisinger T (1997). "Characterization of alpha-ketoglutarate-dependent taurine dioxygenase from Escherichia coli." J Biol Chem 1997;272(37);23031-6. PMID: 9287300

Elling95: Elling L (1995). "Effect of metal ions on sucrose synthase from rice grains--a study on enzyme inhibition and enzyme topography." Glycobiology 1995;5(2);201-6. PMID: 7780195

Falkenberg90: Falkenberg P, Strom AR (1990). "Purification and characterization of osmoregulatory betaine aldehyde dehydrogenase of Escherichia coli." Biochim Biophys Acta 1990;1034(3);253-9. PMID: 2194570

Fernandes10: Fernandes C, Mendes V, Costa J, Empadinhas N, Jorge C, Lamosa P, Santos H, da Costa MS (2010). "Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis." J Bacteriol 192(6);1624-33. PMID: 20061481

Friedmann07: Friedmann S, Alber BE, Fuchs G (2007). "Properties of R-citramalyl-coenzyme A lyase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus." J Bacteriol 189(7);2906-14. PMID: 17259315

Fujiwara97: Fujiwara H, Tanaka Y, Fukui Y, Nakao M, Ashikari T, Kusumi T (1997). "Anthocyanin 5-aromatic acyltransferase from Gentiana triflora. Purification, characterization and its role in anthocyanin biosynthesis." Eur J Biochem 249(1);45-51. PMID: 9363752

Fujiwara98: Fujiwara H, Tanaka Y, Fukui Y, Ashikari T, Yamaguchi M, Kusumi T (1998). "Purification and characterization of anthocyanin 3-aromatic acyltransferase from Perilla frutescens." Plant Science, 137, 87-94.

Fukatsu04: Fukatsu H, Hashimoto Y, Goda M, Higashibata H, Kobayashi M (2004). "Amine-synthesizing enzyme N-substituted formamide deformylase: screening, purification, characterization, and gene cloning." Proc Natl Acad Sci U S A 101(38);13726-31. PMID: 15358859

Funa05: Funa N, Funabashi M, Yoshimura E, Horinouchi S (2005). "A novel quinone-forming monooxygenase family involved in modification of aromatic polyketides." J Biol Chem 280(15);14514-23. PMID: 15701630

Gaudreault81: Gaudreault, P.R., Webb, J.A. (1981). "Stachyose synthesis in leaves of Cucurbita pepo." Phytochemistry 20:2629-2633.

Gibello94: Gibello A, Ferrer E, Martin M, Garrido-Pertierra A (1994). "3,4-Dihydroxyphenylacetate 2,3-dioxygenase from Klebsiella pneumoniae, a Mg(2+)-containing dioxygenase involved in aromatic catabolism." Biochem J 301 ( Pt 1);145-50. PMID: 8037662

Gluck88: Gluck M, Lingens F (1988). "Heteroxanthinedemethylase, a new enzyme in the degradation of caffeine by Pseudomonas putida." Appl. Microbiol. Biotechnol. 28:59-62.

Gonzalez06: Gonzalez CF, Proudfoot M, Brown G, Korniyenko Y, Mori H, Savchenko AV, Yakunin AF (2006). "Molecular basis of formaldehyde detoxification: Characterization of two s-formylglutathione hydrolases from Escherichia coli, FrmB and YeiG." J Biol Chem 281:14514-14522. PMID: 16567800

Greiner01: Greiner R, Muzquiz M, Burbano C, Cuadrado C, Pedrosa MM, Goyoaga C (2001). "Purification and characterization of a phytate-degrading enzyme from germinated faba beans (Vicia faba Var. Alameda)." J Agric Food Chem 49(5);2234-40. PMID: 11368582

Greiner02: Greiner R (2002). "Purification and characterization of three phytases from germinated lupine seeds (Lupinus albus var. amiga)." J Agric Food Chem 50(23);6858-64. PMID: 12405788

Haavik91: Haavik J, Le Bourdelles B, Martinez A, Flatmark T, Mallet J (1991). "Recombinant human tyrosine hydroxylase isozymes. Reconstitution with iron and inhibitory effect of other metal ions." Eur J Biochem 199(2);371-8. PMID: 1676967

Haeusler92: Haeusler PA, Dieter L, Rittle KJ, Shepler LS, Paszkowski AL, Moe OA (1992). "Catalytic properties of Escherichia coli polyphosphate kinase: an enzyme for ATP regeneration." Biotechnol Appl Biochem 1992;15(2);125-33. PMID: 1316760

Halbwirth97: Halbwirth H, Wimmer G, Wurst F, Forkmann G, Stich K (1997). "Enzymatic glucosylation of 4-deoxyaurones and 6'-deoxychalcones with enzyme extracts of Coreopsis grandiflora Nutt. I." Plant Science, 122, 125-131.

Hamai97: Hamai A, Hashimoto N, Mochizuki H, Kato F, Makiguchi Y, Horie K, Suzuki S (1997). "Two distinct chondroitin sulfate ABC lyases. An endoeliminase yielding tetrasaccharides and an exoeliminase preferentially acting on oligosaccharides." J Biol Chem 272(14);9123-30. PMID: 9083041

HammerJespersen70: Hammer-Jespersen K, Munch-Petersen A (1970). "Phosphodeoxyribomutase from Escherichia coli. Purification and some properties." Eur J Biochem 1970;17(3);397-407. PMID: 4992818

Hanschmann96: Hanschmann H, Ehricht R, Kleber HP (1996). "Purification and properties of L(-)-carnitine dehydrogenase from Agrobacterium sp." Biochim Biophys Acta 1290(2);177-83. PMID: 8645721

Helmward89: Helmward Z "Handbook of Enzyme Inhibitors. 2nd, revised and enlarged edition." Weinheim, Federal Republic of Germany ; New York, NY, USA , 1989.

Henrich93: Henrich B, Becker S, Schroeder U, Plapp R (1993). "dcp gene of Escherichia coli: cloning, sequencing, transcript mapping, and characterization of the gene product." J Bacteriol 175(22);7290-300. PMID: 8226676

Hibi92: Hibi N, Fujita T, Hatano M, Hashimoto T, Yamada Y (1992). "Putrescine N-Methyltransferase in Cultured Roots of Hyoscyamus albus: n-Butylamine as a Potent Inhibitor of the Transferase both in Vitro and in Vivo." Plant Physiol 100(2);826-835. PMID: 16653064

Hill67: Hill DL, Chambers P (1967). "The biosynthesis of proline by Tetrahymena pyriformis." Biochim Biophys Acta 148(2);435-47. PMID: 6075416

Hochstadt78: Hochstadt J (1978). "Hypoxanthine phosphoribosyltransferase and guanine phosphoribosyltransferase from enteric bacteria." Methods Enzymol 1978;51;549-58. PMID: 692401

Hochstadt78a: Hochstadt J (1978). "Adenine phosphoribosyltransferase from Escherichia coli." Methods Enzymol 1978;51;558-67. PMID: 357906

Hohlfeld95: Hohlfeld H, Schurmann W, Scheel D, Strack D (1995). "Partial Purification and Characterization of Hydroxycinnamoyl-Coenzyme A:Tyramine Hydroxycinnamoyltransferase from Cell Suspension Cultures of Solanum tuberosum." Plant Physiol 107(2);545-552. PMID: 12228382

Ibdah03: Ibdah M, Zhang XH, Schmidt J, Vogt T (2003). "A novel Mg(2+)-dependent O-methyltransferase in the phenylpropanoid metabolism of Mesembryanthemum crystallinum." J Biol Chem 278(45);43961-72. PMID: 12941960

Iijima06: Iijima Y, Wang G, Fridman E, Pichersky E (2006). "Analysis of the enzymatic formation of citral in the glands of sweet basil." Arch Biochem Biophys 448(1-2);141-9. PMID: 16150417

Ishikawa00: Ishikawa M, Kuroyama H, Takeuchi Y, Tsumuraya Y (2000). "Characterization of pectin methyltransferase from soybean hypocotyls." Planta 210(5);782-91. PMID: 10805450

Ishikura94: Ishikura N, Yang Z-Q (1994). "Multiple forms of flavonol O-glucosyltransferases in young leaves of Euonymus alatus F. ciliato-dentatus." Phytochemistry 36(5): 1139-1145.

Issaly74: Issaly IM, Issaly AS (1974). "Control of ornithine carbamoyltransferase activityby arginase in Bacillus subtilis." Eur J Biochem 1974;49(3);485-95. PMID: 4216455

Jackman99: Jackman JE, Raetz CR, Fierke CA (1999). "UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase of Escherichia coli is a zinc metalloenzyme." Biochemistry 1999;38(6);1902-11. PMID: 10026271

JavidMajd00: Javid-Majd F, Blanchard JS (2000). "Mechanistic analysis of the argE-encoded N-acetylornithine deacetylase." Biochemistry 2000;39(6);1285-93. PMID: 10684608

Jobst10: Jobst B, Schuhle K, Linne U, Heider J (2010). "ATP-dependent carboxylation of acetophenone by a novel type of carboxylase." J Bacteriol 192(5);1387-94. PMID: 20047908

Jones94: Jones RM, Jordan PM (1994). "Purification and properties of porphobilinogen deaminase from Arabidopsis thaliana." Biochem J 299 ( Pt 3);895-902. PMID: 8192681

Jung86: Jung E, Zamir LO, Jensen RA (1986). "Chloroplasts of higher plants synthesize L-phenylalanine via L-arogenate." Proc Natl Acad Sci U S A 83(19);7231-5. PMID: 3463961

Kang95: Kang C, Fromm HJ (1995). "Identification of an essential second metal ion in the reaction mechanism of Escherichia coli adenylosuccinate synthetase." J Biol Chem 270(26);15539-44. PMID: 7797548

Kaschabek02: Kaschabek SR, Kuhn B, Muller D, Schmidt E, Reineke W (2002). "Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: purification and characterization of 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase." J Bacteriol 184(1);207-15. PMID: 11741862

Kataoka97: Kataoka M, Wada M, Nishi K, Yamada H, Shimizu S (1997). "Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39." FEMS Microbiol Lett 151(2);245-8. PMID: 9228760

Kawai01: Kawai S, Suzuki S, Mori S, Murata K (2001). "Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase." FEMS Microbiol Lett 200(2);181-4. PMID: 11425472

Kelley84: Kelley JJ, Dekker EE (1984). "D-1-amino-2-propanol:NAD+ oxidoreductase. Purification and general properties of the large molecular form of the enzyme from Escherichia coli K12." J Biol Chem 1984;259(4);2124-9. PMID: 6365902

Kersten82: Kersten PJ, Dagley S, Whittaker JW, Arciero DM, Lipscomb JD (1982). "2-pyrone-4,6-dicarboxylic acid, a catabolite of gallic acids in Pseudomonas species." J Bacteriol 1982;152(3);1154-62. PMID: 7142106

Khouri86: Khouri HE, Ishikura N, Ibrahim RK (1986). "Fast protein liquid chromatographic purification and some properties of a partially O-methylated flavonol glucoside 2'/5'-O-methyltransferase." Phytochemistry 25(11): 2475-2479.

Khouri88: Khouri HE, De Luca V, Ibrahim RK (1988). "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. III. Purification and kinetic analysis of S-adenosyl-L-methionine:3-methylquercetin 7-O-methyltransferase." Arch Biochem Biophys 265(1);1-7. PMID: 3415239

Kim93: Kim IY, Veres Z, Stadtman TC (1993). "Biochemical analysis of Escherichia coli selenophosphate synthetase mutants. Lysine 20 is essential for catalytic activity and cysteine 17/19 for 8-azido-ATP derivatization." J Biol Chem 1993;268(36);27020-5. PMID: 8262938

Kim94: Kim IY, Stadtman TC (1994). "Effects of monovalent cations and divalent metal ions on Escherichia coli selenophosphate synthetase." Proc Natl Acad Sci U S A 91(15);7326-9. PMID: 8041789

Kita84: Kita K, Konishi K, Anraku Y (1984). "Terminal oxidases of Escherichia coli aerobic respiratory chain. I. Purification and properties of cytochrome b562-o complex from cells in the early exponential phase of aerobic growth." J Biol Chem 1984;259(5);3368-74. PMID: 6365921

Kita86: Kita K, Konishi K, Anraku Y (1986). "Purification and properties of two terminal oxidase complexes of Escherichia coli aerobic respiratory chain." Methods Enzymol 1986;126;94-113. PMID: 2856144

Kizawa95: Kizawa, H., Miyagawa, K., Sugiyama, Y. (1995). "Purification and characterization of trehalose phosphorylase from Micrococcus varians." Biosci. Biotech. Biochem. 59(10):1908-1912.

Kleinhofs67: Kleinhofs A, Haskins A, Gorz HJ (1967). "Trans-O-hydroxycinnamic acid glucosylation in cell-free extracts of Melilotus alba." Phytochemistry, 6, 1313-1318.

Klomklang05: Klomklang W, Tani A, Kimbara K, Mamoto R, Ueda T, Shimao M, Kawai F (2005). "Biochemical and molecular characterization of a periplasmic hydrolase for oxidized polyvinyl alcohol from Sphingomonas sp. strain 113P3." Microbiology 151(Pt 4);1255-62. PMID: 15817792

Koeduka06: Koeduka T, Fridman E, Gang DR, Vassao DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E (2006). "Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester." Proc Natl Acad Sci U S A 103(26);10128-33. PMID: 16782809

Koeduka09: Koeduka T, Baiga TJ, Noel JP, Pichersky E (2009). "Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain." Plant Physiol 149(1);384-94. PMID: 18987218

Komeda04: Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y (2004). "A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide." Eur J Biochem 271(8);1580-90. PMID: 15066183

Komeda04a: Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y (2004). "S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase." Eur J Biochem 271(8);1465-75. PMID: 15066172

Kosuge62: Kosuge T, Conn EE (1962). "The metabolism of aromatic compounds in higher plants. V. Purification and properties of dihydrocoumarin hydrolase of Melilotus alba." J Biol Chem 237;1653-6. PMID: 14458747

Krafft98: Krafft T, Macy JM (1998). "Purification and characterization of the respiratory arsenate reductase of Chrysiogenes arsenatis." Eur J Biochem 255(3);647-53. PMID: 9738904

Kuo82: Kuo LC, Lipscomb WN, Kantrowitz ER (1982). "Zn(II)-induced cooperativity of Escherichia coli ornithine transcarbamoylase." Proc Natl Acad Sci U S A 1982;79(7);2250-4. PMID: 7048313

Kuo83: Kuo LC "Allosteric cofactor-mediated enzyme cooperativity: A theoretical treatment." Proc Natl Acad Sci USA 1983;80:3243-3247.

Laiz90: Laiz L, Liras P, Castro JM, Martin JF (1990). "Purification and characterization of the isopenicillin N epimerase from Nocardia lactamdurans." Journal of General Microbiology 136, 663-671.

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Lehle73: Lehle L, Tanner W (1973). "The function of myo-inositol in the biosynthesis of raffinose. Purification and characterization of galactinol:sucrose 6-galactosyltransferase from Vicia faba seeds." Eur J Biochem 38(1);103-10. PMID: 4774118

Lenz95: Lenz R, Zenk MH (1995). "Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis." J Biol Chem 270(52);31091-6. PMID: 8537369

Lim66: Lim R, Cohen SS (1966). "D-phosphoarabinoisomerase and D-ribulokinase in Escherichia coli." J Biol Chem 1966;241(19);4304-15. PMID: 5332197

Liu09: Liu X, Walsh CT (2009). "Characterization of cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase in cyclopiazonic acid biosynthesis: substrate promiscuity and site directed mutagenesis studies." Biochemistry 48(46);11032-44. PMID: 19877600

Liu14: Liu C, Noike M, Minami A, Oikawa H, Dairi T (2014). "Functional analysis of a prenyltransferase gene (paxD) in the paxilline biosynthetic gene cluster." Appl Microbiol Biotechnol 98(1);199-206. PMID: 23525886

Liu99d: Liu BH, Bhatnagar D, Chu FS (1999). "Purification and characterization of 40-kDa sterigmatocystin O-methyltransferase involved in aflatoxin biosynthesis." Nat Toxins 7(2);63-9. PMID: 10495468

Liu99e: Liu J, Benedict CR, Stipanovic RD, Bell AA (1999). "Purification and Characterization of S-Adenosyl-L-Methionine: Desoxyhemigossypol-6-O-Methyltransferase from Cotton Plants. An Enzyme Capable of Methylating the Defense Terpenoids of Cotton." Plant Physiol 121(3);1017-1024. PMID: 10557251

Llamas06: Llamas A, Otte T, Multhaup G, Mendel RR, Schwarz G (2006). "The Mechanism of nucleotide-assisted molybdenum insertion into molybdopterin. A novel route toward metal cofactor assembly." J Biol Chem 281(27);18343-50. PMID: 16636046

Lord72: Lord JM (1972). "Glycolate oxidoreductase in Escherichia coli." Biochim Biophys Acta 1972;267(2);227-37. PMID: 4557653

Loscos06: Loscos J, Naya L, Ramos J, Clemente MR, Matamoros MA, Becana M (2006). "A reassessment of substrate specificity and activation of phytochelatin synthases from model plants by physiologically relevant metals." Plant Physiol 140(4);1213-21. PMID: 16489135

Lu07: Lu ZJ, Markham GD (2007). "Metal ion activation of S-adenosylmethionine decarboxylase reflects cation charge density." Biochemistry 46(27);8172-80. PMID: 17567041

Lum02: Lum HK, Kwok F, Lo SC (2002). "Cloning and characterization of Arabidopsis thaliana pyridoxal kinase." Planta 215(5);870-9. PMID: 12244454

Lunn00: Lunn JE, Ashton AR, Hatch MD, Heldt HW (2000). "Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants." Proc Natl Acad Sci U S A 2000;97(23);12914-9. PMID: 11050182

Manne86: Manne V, Kutty KR, Pillarisetti SR (1986). "Purification and properties of synephrinase from Arthrobacter synephrinum." Arch Biochem Biophys 248(1);324-34. PMID: 3729420

Marmstal79: Marmstal E, Aronsson AC, Mannervik B (1979). "Comparison of glyoxalase I purified from yeast (Saccharomyces cerevisiae) with the enzyme from mammalian sources." Biochem J 1979;183(1);23-30. PMID: 393249

Maruyama83: Maruyama K (1983). "Purification and properties of 2-pyrone-4,6-dicarboxylate hydrolase." J Biochem (Tokyo) 93(2);557-65. PMID: 6841353

Maruyama85: Maruyama K (1985). "Purification and properties of gamma-oxalomesaconate hydratase from Pseudomonas ochraceae grown with phthalate." Biochem Biophys Res Commun 128(1);271-7. PMID: 3985968

Marvil77: Marvil DK, Leisinger T (1977). "N-acetylglutamate synthase of Escherichia coli: purification, characterization, and molecular properties." J Biol Chem 1977;252(10);3295-303. PMID: 16890

Masai99: Masai E, Shinohara S, Hara H, Nishikawa S, Katayama Y, Fukuda M (1999). "Genetic and biochemical characterization of a 2-pyrone-4, 6-dicarboxylic acid hydrolase involved in the protocatechuate 4, 5-cleavage pathway of Sphingomonas paucimobilis SYK-6." J Bacteriol 181(1);55-62. PMID: 9864312

Mayaux81: Mayaux JF, Blanquet S (1981). "Binding of zinc to Escherichia coli phenylalanyl transfer ribonucleic acid synthetase. Comparison with other aminoacyl transfer ribonucleic acid synthetases." Biochemistry 20(16);4647-54. PMID: 6794600

Meredith03: Meredith TC, Woodard RW (2003). "Escherichia coli YrbH is a D-arabinose 5-phosphate isomerase." J Biol Chem 278(35);32771-7. PMID: 12805358

Meredith05: Meredith TC, Woodard RW (2005). "Identification of GutQ from Escherichia coli as a D-arabinose 5-phosphate isomerase." J Bacteriol 187(20);6936-42. PMID: 16199563

Montella05: Montella C, Bellsolell L, Perez-Luque R, Badia J, Baldoma L, Coll M, Aguilar J (2005). "Crystal structure of an iron-dependent group III dehydrogenase that interconverts L-lactaldehyde and L-1,2-propanediol in Escherichia coli." J Bacteriol 187(14);4957-66. PMID: 15995211

Moracci00: Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M (2000). "Identification and molecular characterization of the first alpha -xylosidase from an archaeon." J Biol Chem 275(29);22082-9. PMID: 10801892

Mori88: Mori, N., Kasugai, T., Kitamato, Y., Ichikawa, Y. (1988). "Purification and some properties of carnitine dehydrogenase from Xanthomonas translucens." Agric. Biol. Chem. 52, 249-250.

Mori95: Mori H, Iida A, Teshiba S, Fujio T (1995). "Cloning of a guanosine-inosine kinase gene of Escherichia coli and characterization of the purified gene product." J Bacteriol 177(17);4921-6. PMID: 7665468

Morishige00: Morishige T, Tsujita T, Yamada Y, Sato F (2000). "Molecular characterization of the S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica." J Biol Chem 275(30);23398-405. PMID: 10811648

Morizono97a: Morizono H, Tuchman M, Rajagopal BS, McCann MT, Listrom CD, Yuan X, Venugopal D, Barany G, Allewell NM (1997). "Expression, purification and kinetic characterization of wild-type human ornithine transcarbamylase and a recurrent mutant that produces 'late onset' hyperammonaemia." Biochem J 322 ( Pt 2);625-31. PMID: 9065786

Muraki03: Muraki T, Taki M, Hasegawa Y, Iwaki H, Lau PC (2003). "Prokaryotic homologs of the eukaryotic 3-hydroxyanthranilate 3,4-dioxygenase and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in the 2-nitrobenzoate degradation pathway of Pseudomonas fluorescens strain KU-7." Appl Environ Microbiol 69(3);1564-72. PMID: 12620844

Nagai91: Nagai A, Scheidegger A (1991). "Purification and characterization of histidinol dehydrogenase from cabbage." Arch Biochem Biophys 284(1);127-32. PMID: 1989490

Nakada95: Nakada T, Maruta K, Mitsuzumi H, Kubota M, Chaen H, Sugimoto T, Kurimoto M, Tsujisaka Y (1995). "Purification and characterization of a novel enzyme, maltooligosyl trehalose trehalohydrolase, from Arthrobacter sp. Q36." Biosci Biotechnol Biochem 59(12);2215-8. PMID: 8611745

Nakao90: Nakao H, Shinoda S, Yamamoto S (1990). "Purification and properties of carboxynorspermidine decarboxylase, a novel enzyme involved in norspermidine biosynthesis, from Vibrio alginolyticus." Journal of General Microbiology 136, 1699-1704.

Nandi79: Nandi DL, Lucas SV, Webster LT (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization." J Biol Chem 254(15);7230-7. PMID: 457678

Negishi94: Negishi, Osamu, Ozawa, Tetsuo, Imagawa, Hiroshi (1994). "Guanosine deaminase and guanine deaminase from tea leaves." Biosci. Biotech. Biochem. 58(7): 1277-1281.

Newman80: Newman EB, Kapoor V (1980). "In vitro studies on L-serine deaminase activity of Escherichia coli K12." Can J Biochem 1980;58(11);1292-7. PMID: 7011505

Nishimoto96: Nishimoto T, Nakano M, Nakada T, Chaen H, Fukuda S, Sugimoto T, Kurimoto M, Tsujisaka Y (1996). "Purification and properties of a novel enzyme, trehalose synthase, from Pimelobacter sp. R48." Biosci Biotechnol Biochem 60(4);640-4. PMID: 8829531

Nishimoto96a: Nishimoto, T., Nakada, T., Chaen, H., Fukuda, S., Sugimoto, T., Kurimoto, M., Tsujisaka, Y. (1996). "Purification and characterization of a thermostable trehalose synthase from Thermus aquaticus." Biosci. Biotech. Biochem. 60(5):835-839.

Nualkaew06: Nualkaew N, De-Eknamkul W, Kutchan TM, Zenk MH (2006). "Membrane-bound geranylgeranyl diphosphate phosphatases: purification and characterization from Croton stellatopilosus leaves." Phytochemistry 67(15);1613-20. PMID: 16445953

Obradors98: Obradors N, Cabiscol E, Aguilar J, Ros J (1998). "Site-directed mutagenesis studies of the metal-binding center of the iron-dependent propanediol oxidoreductase from Escherichia coli." Eur J Biochem 258(1);207-13. PMID: 9851711

Oikawa02: Oikawa A, Ishihara A, Iwamura H (2002). "Induction of HDMBOA-Glc accumulation and DIMBOA-Glc 4-O-methyltransferase by jasmonic acid in poaceous plants." Phytochemistry 61(3);331-7. PMID: 12359519

Orii04: Orii C, Takenaka S, Murakami S, Aoki K (2004). "A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid in Bordetella sp. strain 10d." Eur J Biochem 271(15);3248-54. PMID: 15265044

Orii06: Orii C, Takenaka S, Murakami S, Aoki K (2006). "Metabolism of 4-amino-3-hydroxybenzoic acid by Bordetella sp. strain 10d: A different modified meta-cleavage pathway for 2-aminophenols." Biosci Biotechnol Biochem 70(11);2653-61. PMID: 17090920

Oven02: Oven M, Page JE, Zenk MH, Kutchan TM (2002). "Molecular characterization of the homo-phytochelatin synthase of soybean Glycine max: relation to phytochelatin synthase." J Biol Chem 277(7);4747-54. PMID: 11706029

Owens: Owens DK, McIntosh CA "Identification, recombinant expression, and biochemical characterization of a flavonol 3-O-glucosyltransferase clone from Citrus paradisi." Phytochemistry 70(11-12);1382-91. PMID: 19733370

Park93a: Park YS, Sweitzer TD, Dixon JE, Kent C (1993). "Expression, purification, and characterization of CTP:glycerol-3-phosphate cytidylyltransferase from Bacillus subtilis." J Biol Chem 268(22);16648-54. PMID: 8393871

Payton82: Payton CW, Chang YF (1982). "delta1-piperideine-2-carboxylate reductase of Pseudomonas putida." J Bacteriol 149(3);864-71. PMID: 6801013

Peterbauer98: Peterbauer T, Richter A (1998). "Galactosylononitol and stachyose synthesis in seeds of adzuki bean. Purification and characterization of stachyose synthase." Plant Physiol 117(1);165-72. PMID: 9576785

Petrusma09: Petrusma M, Dijkhuizen L, van der Geize R (2009). "Rhodococcus rhodochrous DSM 43269 3-ketosteroid 9alpha-hydroxylase, a two-component iron-sulfur-containing monooxygenase with subtle steroid substrate specificity." Appl Environ Microbiol 75(16);5300-7. PMID: 19561185

Pfleger08: Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH (2008). "Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis." Proc Natl Acad Sci U S A 105(44);17133-8. PMID: 18955706

Phalip94: Phalip V, Monnet C, Schmitt P, Renault P, Godon JJ, Divies C (1994). "Purification and properties of the alpha-acetolactate decarboxylase from Lactococcus lactis subsp. lactis NCDO 2118." FEBS Lett 351(1);95-9. PMID: 8076701

Picaud06: Picaud S, Olsson ME, Brodelius M, Brodelius PE (2006). "Cloning, expression, purification and characterization of recombinant (+)-germacrene D synthase from Zingiber officinale." Arch Biochem Biophys 452(1);17-28. PMID: 16839518

Plateau82: Plateau P, Blanquet S (1982). "Zinc-dependent synthesis of various dinucleoside 5',5' ' '-P1,P3-Tri- or 5'',5' ' '-P1,P4-tetraphosphates by Escherichia coli lysyl-tRNA synthetase." Biochemistry 21(21);5273-9. PMID: 6756470

Portalier72: Portalier RC, Stoeber FR (1972). "[D-mannonate: NAD oxidoreductase from Escherichia coli K12. Purification, properties and specificity]." Eur J Biochem 1972;26(2);290-300. PMID: 4402996

Porter93: Porter DJ, Austin EA (1993). "Cytosine deaminase. The roles of divalent metal ions in catalysis." J Biol Chem 1993;268(32);24005-11. PMID: 8226944

Powlowski93: Powlowski J, Sahlman L, Shingler V (1993). "Purification and properties of the physically associated meta-cleavage pathway enzymes 4-hydroxy-2-ketovalerate aldolase and aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600." J Bacteriol 175(2);377-85. PMID: 8419288

Psylinakis05: Psylinakis E, Boneca IG, Mavromatis K, Deli A, Hayhurst E, Foster SJ, Varum KM, Bouriotis V (2005). "Peptidoglycan N-acetylglucosamine deacetylases from Bacillus cereus, highly conserved proteins in Bacillus anthracis." J Biol Chem 280(35);30856-63. PMID: 15961396

Pucci07: Pucci L, Perozzi S, Cimadamore F, Orsomando G, Raffaelli N (2007). "Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism." FEBS J 274(3);827-40. PMID: 17288562

Raha90: Raha SK, Roy SK, Dey SK, Chakrabarty SL (1990). "Purification and properties of an L-asparaginase from Cylindrocarpon obtusisporum MB-10." Biochem Int 21(6);987-1000. PMID: 2080924

Rajakumari10: Rajakumari S, Daum G (2010). "Janus-faced enzymes yeast Tgl3p and Tgl5p catalyze lipase and acyltransferase reactions." Mol Biol Cell 21(4);501-10. PMID: 20016004

Rakwal00: Rakwal R, Agrawal GK, Yonekura M, Kodama O (2000). "Naringenin 7-O-methyltransferase involved in the biosynthesis of the flavanone phytoalexin sakuranetin from rice (Oryza sativa L.)." Plant Science 155(2);213-221. PMID: 10814825

Rautengarten12: Rautengarten C, Ebert B, Ouellet M, Nafisi M, Baidoo EE, Benke P, Stranne M, Mukhopadhyay A, Keasling JD, Sakuragi Y, Scheller HV (2012). "Arabidopsis Deficient in Cutin Ferulate encodes a transferase required for feruloylation of ω-hydroxy fatty acids in cutin polyester." Plant Physiol 158(2);654-65. PMID: 22158675

Ray80: Ray PH (1980). "Purification and characterization of 3-deoxy-D-manno-octulosonate 8-phosphate synthetase from Escherichia coli." J Bacteriol 1980;141(2);635-44. PMID: 6988389

Reed93a: Reed DW, Davin L, Jain JC, Deluca V, Nelson L, Underhill EW (1993). "Purification and properties of UDP-glucose:thiohydroximate glucosyltransferase from Brassica napus L. seedlings." Arch Biochem Biophys 305(2);526-32. PMID: 8373190

Reitz70: Reitz MS, Rodwell VW (1970). "Delta-aminovaleramidase of Pseudomonas putida." J Biol Chem 245(12);3091-6. PMID: 5432799

Richard98: Richard MG, McMaster CR (1998). "Lysophosphatidylcholine acyltransferase activity in Saccharomyces cerevisiae: regulation by a high-affinity Zn2+ binding site." Lipids 33(12);1229-34. PMID: 9930410

Rigo76: Rigo LU, Nakano M, Veiga LA, Feingold DS (1976). "L-rhamnose dehydrogenase of Pullularia pullulans." Biochimica et Biophysica Acta 445, 286-293.

RodriguezAparic92: Rodriguez-Aparicio LB, Luengo JM, Gonzalez-Clemente C, Reglero A (1992). "Purification and characterization of the nuclear cytidine 5'-monophosphate N-acetylneuraminic acid synthetase from rat liver." J Biol Chem 267(13);9257-63. PMID: 1577759

Rubio98: Rubio MA, Espinosa JC, Tercero JA, Jimenez A (1998). "The Pur10 protein encoded in the gene cluster for puromycin biosynthesis of Streptomyces alboniger is an NAD-dependent ATP dehydrogenase." FEBS Lett 437(3);197-200. PMID: 9824289

Ryzhova98: Ryzhova TA, Andreichuk YV, Domkin VD (1998). "Adenylosuccinate synthetase of the yeast Saccharomyces cerevisiae: purification and properties." Biochemistry (Mosc) 1998;63(6);650-6. PMID: 9668204

Sachan80: Sachan DS, Hoppel CL (1980). "Carnitine biosynthesis. Hydroxylation of N6-trimethyl-lysine to 3-hydroxy-N6-trimethyl-lysine." Biochem J 188(2);529-34. PMID: 6772170

Saikusa87: Saikusa T, Rhee H, Watanabe K, Murata K, Kimura A (1987). "Metabolism of 2-oxoaldehydes in bacteria: purification and characterization of methylglyoxal reductase from E. coli." Agricultural and Biological Chemistry 51(7): 1893-1899.

SaintJean98: Saint-Jean AP, Phillips KR, Creighton DJ, Stone MJ (1998). "Active monomeric and dimeric forms of Pseudomonas putida glyoxalase I: evidence for 3D domain swapping." Biochemistry 37(29);10345-53. PMID: 9671502

Saito98: Saito K, Kase T, Takahashi E, Horinouchi S (1998). "Purification and characterization of a trehalose synthase from the basidiomycete Grifola frondosa." Appl Environ Microbiol 64(11);4340-5. PMID: 0009797287

Sangwan90: Sangwan RS, Singh R (1990). "Characterization of amyloplastic phosphohexose isomerase from immature wheat (Triticum aestivum L.) endosperm." Indian J Biochem Biophys 27(1);23-7. PMID: 2341161

Sato94: Sato F, Tsujita T, Katagiri Y, Yoshida S, Yamada Y (1994). "Purification and characterization of S-adenosyl-L-methionine: norcoclaurine 6-O-methyltransferase from cultured Coptis japonica cells." Eur J Biochem 225(1);125-31. PMID: 7925429

Satyanarayana71: Satyanarayana T, Kaplan JG (1971). "Regulation of the purine pathway in bakers yeast: activity and feedback inhibition of phosphoribosyl-pyrophosphate amidotransferase." Arch Biochem Biophys 1971;142(1);40-7. PMID: 4322810

Scharf13: Scharf DH, Chankhamjon P, Scherlach K, Heinekamp T, Willing K, Brakhage AA, Hertweck C (2013). "Epidithiodiketopiperazine biosynthesis: a four-enzyme cascade converts glutathione conjugates into transannular disulfide bridges." Angew Chem Int Ed Engl 52(42);11092-5. PMID: 24039048

Schneider08: Schneider P, Weber M, Hoffmeister D (2008). "The Aspergillus nidulans enzyme TdiB catalyzes prenyltransfer to the precursor of bioactive asterriquinones." Fungal Genet Biol 45(3);302-9. PMID: 18029206

Schroeder94: Schroeder U, Henrich B, Fink J, Plapp R (1994). "Peptidase D of Escherichia coli K-12, a metallopeptidase of low substrate specificity." FEMS Microbiol Lett 123(1-2);153-9. PMID: 7988883

Shi05a: Shi F, Kawai S, Mori S, Kono E, Murata K (2005). "Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae." FEBS J 272(13);3337-49. PMID: 15978040

Shigeoka79: Shigeoka S, Nakano Y, Kitaoka S (1979). "Some properties and subcellular localization of L-gulono-γ-lactone dehydrogenase in Euglena gracilis z." Agric. Biol. Chem. 43 (10) 2187-2188.

Simms84: Simms SA, Voige WH, Gilvarg C (1984). "Purification and characterization of succinyl-CoA: tetrahydrodipicolinate N-succinyltransferase from Escherichia coli." J Biol Chem 1984;259(5);2734-41. PMID: 6365916

Stabler85: Stabler SP, Marcell PD, Allen RH (1985). "Isolation and characterization of DL-methylmalonyl-coenzyme A racemase from rat liver." Arch Biochem Biophys 241(1);252-64. PMID: 2862845

Steffek03: Steffek M, Newton GL, Av-Gay Y, Fahey RC (2003). "Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase." Biochemistry 42(41);12067-76. PMID: 14556638

Stich94: Stich K, Halbwirth H, Wurst F, Forkmann G (1994). "Formation of 6'-deoxychalcone 4'-glucosides by enzyme extracts from petals of Dahlia variabilis." Z. Naturforsch., 49c, 737-741.

Subedi11: Subedi KP, Choi D, Kim I, Min B, Park C (2011). "Hsp31 of Escherichia coli K-12 is glyoxalase III." Mol Microbiol 81(4);926-36. PMID: 21696459

Sugimori13: Sugimori D, Ogasawara J, Okuda K, Murayama K (2013). "Purification, characterization, molecular cloning, and extracellular production of a novel bacterial glycerophosphocholine cholinephosphodiesterase from Streptomyces sanglieri." J Biosci Bioeng. PMID: 24211038

Sugio89a: Sugio T, Katagiri T, Inagaki K, Tano T (1989). "Actual substrate for elemental sulfur oxidation by sulfur:ferric ion oxidoreductase purified from Thiobacillus ferrooxidans." Biochimica et Biophysica Acta 973:250-256.

Sugiyama83: Sugiyama M, Sakamoto M, Mochizuki H, Nimi O, Nomi R (1983). "Purification and characterization of streptomycin 6-kinase, an enzyme implicated in self-protection of a streptomycin-producing micro-organism." J Gen Microbiol 129(6);1683-7. PMID: 6313852

Suzuki04a: Suzuki H, Sawada S, Watanabe K, Nagae S, Yamaguchi MA, Nakayama T, Nishino T (2004). "Identification and characterization of a novel anthocyanin malonyltransferase from scarlet sage (Salvia splendens) flowers: an enzyme that is phylogenetically separated from other anthocyanin acyltransferases." Plant J 38(6);994-1003. PMID: 15165190

Sydor13: Sydor AM, Jost M, Ryan KS, Turo KE, Douglas CD, Drennan CL, Zamble DB (2013). "Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases." Biochemistry 52(10);1788-1801. PMID: 24449932

Szumilo81: Szumilo T (1981). "Purification and properties of D-galactonate dehydratase from Mycobacterium butyricum." Biochim Biophys Acta 661(2);240-6. PMID: 7295736

Szumilo96: Szumilo T, Zeng Y, Pastuszak I, Drake R, Szumilo H, Elbein AD (1996). "Purification to homogeneity and properties of UDP-GlcNAc (GalNAc) pyrophosphorylase." J Biol Chem 271(22);13147-54. PMID: 8662687

Taguchi00: Taguchi G, Imura H, Maeda Y, Kodaira R, Hayashida N, Shimosaka M, Okazaki M (2000). "Purification and characterization of UDP-glucose: hydroxycoumarin 7-O-glucosyltransferase, with broad substrate specificity from tobacco cultured cells." Plant Sci 157(1);105-112. PMID: 10940474

Taguchi08: Taguchi H, Hamada S, Kawauchi S, Ito H, Senoura T, Watanabe J, Nishimukai M, Ito S, Matsui H (2008). "Enzymatic properties of cellobiose 2-epimerase from Ruminococcus albus and the synthesis of rare oligosaccharides by the enzyme." Appl Microbiol Biotechnol 79(3);433-41. PMID: 18392616

Takahashi87: Takahashi K, Avissar N, Whitin J, Cohen H (1987). "Purification and characterization of human plasma glutathione peroxidase: a selenoglycoprotein distinct from the known cellular enzyme." Arch Biochem Biophys 256(2);677-86. PMID: 3619451

Takenaka11: Takenaka S, Koshiya J, Okugawa S, Takata A, Murakami S, Aoki K (2011). "Fe-superoxide dismutase and 2-hydroxy-1,4-benzoquinone reductase preclude the auto-oxidation step in 4-aminophenol metabolism by Burkholderia sp. strain AK-5." Biodegradation 22(1);1-11. PMID: 20480210

Tallant01: Tallant TC, Paul L, Krzycki JA (2001). "The MtsA subunit of the methylthiol:coenzyme M methyltransferase of Methanosarcina barkeri catalyses both half-reactions of corrinoid-dependent dimethylsulfide: coenzyme M methyl transfer." J Biol Chem 276(6);4485-93. PMID: 11073950

Tang11: Tang H, Yao Y, Zhang D, Meng X, Wang L, Yu H, Ma L, Xu P (2011). "A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida." J Biol Chem 286(45);39179-87. PMID: 21949128

Tardy97: Tardy F, Nasser W, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N (1997). "Comparative analysis of the five major Erwinia chrysanthemi pectate lyases: enzyme characteristics and potential inhibitors." J Bacteriol 179(8);2503-11. PMID: 9098045

Taylor93: Taylor A (1993). "Aminopeptidases: structure and function." FASEB J 7(2);290-8. PMID: 8440407

Topp00: Topp E, Mulbry WM, Zhu H, Nour SM, Cuppels D (2000). "Characterization of S-triazine herbicide metabolism by a Nocardioides sp. isolated from agricultural soils." Appl Environ Microbiol 2000;66(8);3134-41. PMID: 10919761

Tran10: Tran HT, Qian W, Hurley BA, She YM, Wang D, Plaxton WC (2010). "Biochemical and molecular characterization of AtPAP12 and AtPAP26: the predominant purple acid phosphatase isozymes secreted by phosphate-starved Arabidopsis thaliana." Plant Cell Environ 33(11);1789-803. PMID: 20545876

Treffry98a: Treffry A, Zhao Z, Quail MA, Guest JR, Harrison PM (1998). "The use of zinc(II) to probe iron binding and oxidation by the ferritin (EcFtnA) of Escherichia coli." J. Biol. Inorg. Chem. 3, 682-688.

Tsang79: Tsang Y-F, Ibrahim RK (1979). "Two forms of O-methyltransferase in tobacco cell suspension culture." Phytochemistry 18: 1131-1136.

Tsuge82: Tsuge H, Kuroda Y, Iwamoto A, Ohashi K (1982). "Partial purification and property of pyridoxine (pyridoxamine)-5'-phosphate oxidase isozymes from wheat seedlings." Arch Biochem Biophys 217(2);479-84. PMID: 7138019

Uetz93: Uetz T, Egli T (1993). "Characterization of an inducible, membrane-bound iminodiacetate dehydrogenase from Chelatobacter heintzii ATCC 29600." Biodegradation 3: 423-434.

Umemoto08: Umemoto Y, Onishi R, Araki T (2008). "Cloning of a novel gene encoding beta-1,3-xylosidase from a marine bacterium, Vibrio sp. strain XY-214, and characterization of the gene product." Appl Environ Microbiol 74(1);305-8. PMID: 17993567

Unsold06: Unsold IA, Li SM (2006). "Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1." Chembiochem 7(1);158-64. PMID: 16397874

Upmeier88: Upmeier B, Thomzik JE, Barz W (1988). "Enzymatic studies on the reversible synthesis of nicotinic acid-N-glucoside in heterotrophic parsley cell suspension cultures." Z. Naturforsch. 43c, 835-842.

Uyeda65: Uyeda, K, Rabinowitz, JC (1965). "Metabolism of formiminoglycine. Glycine formiminotransferase." J Biol Chem 240;1701-10. PMID: 14285511

Uyeda67: Uyeda K, Rabinowitz JC (1967). "Metabolism of formiminoglycine. Formiminotetrahydrofolate cyclodeaminase." J Biol Chem 242(1);24-31. PMID: 6016330

Van00: Van Der Werf MJ (2000). "Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways." Biochem J 347 Pt 3;693-701. PMID: 10769172

vanHeijenoort75: van Heijenoort J, Parquet C, Flouret B, van Heijenoort Y (1975). "Envelope-bound N-acetylmuramyl-L-alanine amidase of Escherichia coli K 12. Purification and properties of the enzyme." Eur J Biochem 58(2);611-9. PMID: 1102308

Varbanova07: Varbanova M, Yamaguchi S, Yang Y, McKelvey K, Hanada A, Borochov R, Yu F, Jikumaru Y, Ross J, Cortes D, Ma CJ, Noel JP, Mander L, Shulaev V, Kamiya Y, Rodermel S, Weiss D, Pichersky E (2007). "Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2." Plant Cell 19(1);32-45. PMID: 17220201

Veljanovski06: Veljanovski V, Vanderbeld B, Knowles VL, Snedden WA, Plaxton WC (2006). "Biochemical and molecular characterization of AtPAP26, a vacuolar purple acid phosphatase up-regulated in phosphate-deprived Arabidopsis suspension cells and seedlings." Plant Physiol 142(3);1282-93. PMID: 16963519

Veres94: Veres Z, Kim IY, Scholz TD, Stadtman TC (1994). "Selenophosphate synthetase. Enzyme properties and catalytic reaction." J Biol Chem 269(14);10597-603. PMID: 8144648

Vogel74: Vogel HJ, Vogel RH (1974). "Enzymes of arginine biosynthesis and their repressive control." Adv Enzymol Relat Areas Mol Biol 1974;40(0);65-90. PMID: 4365537

Vogel74b: Vogel, HJ, Vogel, RH "Enzymes of Arginine Biosynthesis." Advances in Enzymology 40:71-72 (1974).

Vogt95: Vogt T, Taylor LP (1995). "Flavonol 3-O-glycosyltransferases associated with petunia pollen produce gametophyte-specific flavonol diglycosides." Plant Physiol 108(3);903-11. PMID: 7630971

Wang11b: Wang B, Wang P, Zheng E, Chen X, Zhao H, Song P, Su R, Li X, Zhu G (2011). "Biochemical properties and physiological roles of NADP-dependent malic enzyme in Escherichia coli." J Microbiol 49(5);797-802. PMID: 22068497

Wang12b: Wang Q, Xu Y, Perepelov AV, Knirel YA, Reeves PR, Shashkov AS, Guo X, Ding P, Feng L (2012). "Biochemical characterization of the CDP-D-arabinitol biosynthetic pathway in Streptococcus pneumoniae 17F." J Bacteriol 194:1868-1874. PMID: 22328666

Wang98e: Wang J, Pichersky E (1998). "Characterization of S-adenosyl-L-methionine:(iso)eugenol O-methyltransferase involved in floral scent production in Clarkia breweri." Arch Biochem Biophys 349(1);153-60. PMID: 9439593

Watanabe08: Watanabe S, Saimura M, Makino K (2008). "Eukaryotic and bacterial gene clusters related to an alternative pathway of nonphosphorylated L-rhamnose metabolism." J Biol Chem 283(29);20372-82. PMID: 18505728

Weber94a: Weber E., Tonder K., Reinbothe C., Unverhau K., Weide H., Aurich H. (1994). "L-Lysine α-oxidase from Trichoderma viride i4. Purification and characterization." J. Basic Microbiol. 34:265-276.

Wiame02: Wiame E, Delpierre G, Collard F, Van Schaftingen E (2002). "Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli." J Biol Chem 277(45);42523-9. PMID: 12147680

Wiame04: Wiame E, Van Schaftingen E (2004). "Fructoselysine 3-epimerase, an enzyme involved in the metabolism of the unusual Amadori compound psicoselysine in Escherichia coli." Biochem J 378(Pt 3);1047-52. PMID: 14641112

Wiesmeyer60: Wiesmeyer H, Cohn M (1960). "The characterization of the pathway of maltose utilization by Escherichia coli: II. General properties and mechanism of action of amylomaltase." Biochim Biophys Acta 39:427-439.

Wrba90: Wrba A, Jaenicke R, Huber R, Stetter KO (1990). "Lactate dehydrogenase from the extreme thermophile Thermotoga maritima." Eur J Biochem 1990;188(1);195-201. PMID: 2318202

Xu03: Xu J, Mahmud T, Floss HG (2003). "Isolation and characterization of 27-O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercular drug rifamycin B by Amycolatopsis mediterranei S699." Arch Biochem Biophys 411(2);277-88. PMID: 12623077

Xu12: Xu FF, Imlay JA (2012). "Silver(I), mercury(II), cadmium(II), and zinc(II) target exposed enzymic iron-sulfur clusters when they toxify Escherichia coli." Appl Environ Microbiol 78(10);3614-21. PMID: 22344668

Yamaguchi94: Yamaguchi H., Kanayama Y., Yamaki S. (1994). "Purification and properties of NAD-dependent sorbitol dehydrogenase from apple fruit." Plant Cell Physiol. 35(6):887-892.

Yamamoto01: Yamamoto K, Kobayashi M, Yoshitama K, Teramoto S, Kosamine A (2001). "Isolation and purification of tyrosine hydroxylase from Portulaca grandiflora." Plant Cell Physiol., 42(9), 969-975.

Yang06a: Yang Y, Yuan JS, Ross J, Noel JP, Pichersky E, Chen F (2006). "An Arabidopsis thaliana methyltransferase capable of methylating farnesoic acid." Arch Biochem Biophys 448(1-2);123-32. PMID: 16165084

Yang11: Yang Z, Chi X, Funabashi M, Baba S, Nonaka K, Pahari P, Unrine J, Jacobsen JM, Elliott GI, Rohr J, Van Lanen SG (2011). "Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis." J Biol Chem 286(10);7885-92. PMID: 21216959

Yokoyama08: Yokoyama K, Yamamoto Y, Kudo F, Eguchi T (2008). "Involvement of two distinct N-acetylglucosaminyltransferases and a dual-function deacetylase in neomycin biosynthesis." Chembiochem 9(6);865-9. PMID: 18311744

Yorifuji77: Yorifuji T, Jeng IM, Barker HA (1977). "Purification and properties of 3-keto-5-aminohexanoate cleavage enzyme from a lysine-fermenting Clostridium." J Biol Chem 252(1);20-31. PMID: 13064

Yoshida70: Yoshida A, Freese E (1970). "L-Alanine dehydrogenase (Bacillus subtilis)." Methods in Enzymology 17:176-181.

Yoshimoto91: Yoshimoto T, Higashi H, Kanatani A, Lin XS, Nagai H, Oyama H, Kurazono K, Tsuru D (1991). "Cloning and sequencing of the 7 alpha-hydroxysteroid dehydrogenase gene from Escherichia coli HB101 and characterization of the expressed enzyme." J Bacteriol 1991;173(7);2173-9. PMID: 2007545

Yu99: Yu M, Facchini PJ (1999). "Purification, characterization, and immunolocalization of hydroxycinnamoyl-CoA: tyramine N-(hydroxycinnamoyl)transferase from opium poppy." Planta 209(1);33-44. PMID: 10467029

Yue05: Yue, C-J, Zhong, J-J (2005). "Purification and characterization of UDPG:ginsenoside Rd glucosyltransferase from suspended cells of Panax notoginseng." Process Biochemistry 40, 3742-3748.

Zahringer13: Zahringer F, Lacanna E, Jenal U, Schirmer T, Boehm A (2013). "Structure and signaling mechanism of a zinc-sensory diguanylate cyclase." Structure 21(7);1149-57. PMID: 23769666

Zhao07: Zhao N, Guan J, Lin H, Chen F (2007). "Molecular cloning and biochemical characterization of indole-3-acetic acid methyltransferase from poplar." Phytochemistry 68(11);1537-44. PMID: 17499822


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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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