MetaCyc Enzyme: nitrile-specifier protein

Gene: AtNSP2 Accession Number: AT2G33070 (MetaCyc)

Synonyms: At2g33070

Species: Arabidopsis thaliana col

Nitrile-specifier proteins (NSP) are independent of epithio-specifier proteins (ESP) in simple nitrile formation. There are five functional NSPs in the Arabidopsis genome. In vitro assay indicated that they act upon both aliphatic and aromatic glucosinolates. Indole glucosinolates were not tested in the study [Burow09].

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Created 31-Jul-2009 by Zhang P , TAIR

Enzymatic reaction of: nitrile-specifier protein

indolylmethyl glucosinolate aglycone <=> indole-3-acetonitrile

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is favored in the direction shown.

In Pathways: indole glucosinolate breakdown (insect chewing induced)


Burow09: Burow M, Losansky A, Muller R, Plock A, Kliebenstein DJ, Wittstock U (2009). "The genetic basis of constitutive and herbivore-induced ESP-independent nitrile formation in Arabidopsis." Plant Physiol 149(1);561-74. PMID: 18987211

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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