Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: aconitase

Gene: Aco Accession Number: G-12154 (MetaCyc)

Species: Aspergillus terreus

Summary:
Aconitase has not been purified from Aspergillus terreus. However, the enzymatic activity has been demonstrated in assays performed with whole cells during the production of itaconate [Bonnarme95].

The Aco gene has been cloned and sequenced, and submitted to Genbank, although the work has not been published.

Molecular Weight of Polypeptide: 84.327 kD (from nucleotide sequence)

Unification Links: Entrez-Nucleotide:AF093142 , Protein Model Portal:O74699 , SMR:O74699 , String:O74699 , UniProt:O74699

Relationship Links: InterPro:IN-FAMILY:IPR000573 , InterPro:IN-FAMILY:IPR001030 , InterPro:IN-FAMILY:IPR006248 , InterPro:IN-FAMILY:IPR015928 , InterPro:IN-FAMILY:IPR015931 , InterPro:IN-FAMILY:IPR015932 , InterPro:IN-FAMILY:IPR015937 , InterPro:IN-FAMILY:IPR018136 , Panther:IN-FAMILY:PTHR11670 , Panther:IN-FAMILY:PTHR11670:SF5 , Pfam:IN-FAMILY:PF00330 , Pfam:IN-FAMILY:PF00694 , Prints:IN-FAMILY:PR00415 , Prosite:IN-FAMILY:PS00450 , Prosite:IN-FAMILY:PS01244

Gene-Reaction Schematic: ?

Credits:
Created 14-Dec-2007 by Caspi R , SRI International


Enzymatic reaction of: aconitase

citrate[mitochondrial lumen] <=> cis-aconitate[mitochondrial lumen] + H2O[mitochondrial lumen]

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: itaconate biosynthesis


References

Bonnarme95: Bonnarme P, Gillet B, Sepulchre AM, Role C, Beloeil JC, Ducrocq C (1995). "Itaconate biosynthesis in Aspergillus terreus." J Bacteriol 177(12);3573-8. PMID: 7768868


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.