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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Enzyme: aconitase

Gene: Aco Accession Number: G-12154 (MetaCyc)

Species: Aspergillus terreus

Summary:
Aconitase has not been purified from Aspergillus terreus. However, the enzymatic activity has been demonstrated in assays performed with whole cells during the production of itaconate [Bonnarme95].

The Aco gene has been cloned and sequenced, and submitted to Genbank, although the work has not been published.

Molecular Weight of Polypeptide: 84.327 kD (from nucleotide sequence)

Unification Links: Entrez-Nucleotide:AF093142 , Protein Model Portal:O74699 , SMR:O74699 , String:O74699 , UniProt:O74699

Relationship Links: InterPro:IN-FAMILY:IPR000573 , InterPro:IN-FAMILY:IPR001030 , InterPro:IN-FAMILY:IPR006248 , InterPro:IN-FAMILY:IPR015928 , InterPro:IN-FAMILY:IPR015931 , InterPro:IN-FAMILY:IPR015932 , InterPro:IN-FAMILY:IPR015937 , InterPro:IN-FAMILY:IPR018136 , Panther:IN-FAMILY:PTHR11670 , Panther:IN-FAMILY:PTHR11670:SF5 , Pfam:IN-FAMILY:PF00330 , Pfam:IN-FAMILY:PF00694 , Prints:IN-FAMILY:PR00415 , Prosite:IN-FAMILY:PS00450 , Prosite:IN-FAMILY:PS01244

Gene-Reaction Schematic: ?

Credits:
Created 14-Dec-2007 by Caspi R , SRI International


Enzymatic reaction of: aconitase

citrate[mitochondrial lumen] <=> cis-aconitate[mitochondrial lumen] + H2O[mitochondrial lumen]

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: itaconate biosynthesis


References

Bonnarme95: Bonnarme P, Gillet B, Sepulchre AM, Role C, Beloeil JC, Ducrocq C (1995). "Itaconate biosynthesis in Aspergillus terreus." J Bacteriol 177(12);3573-8. PMID: 7768868


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc12.