MetaCyc Enzyme: ginsenoside β- glucosidase

Species: Panax ginseng

An enzyme was isolated from roots of Panax ginseng. The protein was purified using ion exchange chromatography and biochemically characterized. The enzyme catalyzed the conversion of (20S)-ginsenoside Rg3 to (20S)-ginsenoside Rh2, it hydrolyzes the β- (1- 2)-glucoside bond of (20S)-ginsenoside Rg3. It also exhibited considerable functional variation from other beta glucosidases [Zhang01d].

Molecular Weight of Polypeptide: 59.0 kD (experimental) [Zhang01d]

Gene-Reaction Schematic

Gene-Reaction Schematic

Created 07-Jan-2010 by Pujar A, Boyce Thompson Institute

Enzymatic reaction of: ginsenoside β- glucosidase

Inferred from experiment

(20S)-ginsenoside Rg3 + H2O → (20S)-ginsenoside Rh2 + D-glucopyranose

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: ginsenoside degradation III

T(opt): 60 °C [Zhang01d]

pH(opt): 5 [Zhang01d]


Zhang01d: Zhang C, Yu H, Bao Y, An L, Jin F (2001). "Purification and characterization of ginsenoside-beta-glucosidase from ginseng." Chem Pharm Bull (Tokyo) 49(7);795-8. PMID: 11456082

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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