Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: neryl diphosphate synthase

Gene: NPDS1 Accession Number: G-11833 (MetaCyc)

Synonyms: neryl diphosphate synthase 1

Species: Solanum lycopersicum

Summary:
A cDNA clone was isolated from the glandular trichomes of tomato. The cDNA was recombinantly expressed in E.coli and it encodes a gene named NPDS1. The enzyme catalyzes the conversion of dimethylallyl diphosphate and isopentenyl diphosphate into neryl diphosphate. The expression of the transcript is specific to glandular trichomes [Schilmiller09].

Molecular Weight of Polypeptide: 34.6 kD (experimental) [Schilmiller09 ]

Unification Links: Entrez-Nucleotide:FJ797956 , Entrez:ACO56895 , Protein Model Portal:C1K5M2 , UniProt:C1K5M2

Relationship Links: InterPro:IN-FAMILY:IPR001441 , InterPro:IN-FAMILY:IPR018520 , Panther:IN-FAMILY:PTHR10291 , Pfam:IN-FAMILY:PF01255 , Prosite:IN-FAMILY:PS01066

Gene-Reaction Schematic: ?

Credits:
Created 02-Mar-2010 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: neryl diphosphate synthase

EC Number: 2.5.1.28

dimethylallyl diphosphate + isopentenyl diphosphate <=> neryl diphosphate + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

In Pathways: trichome monoterpenes biosynthesis


References

Schilmiller09: Schilmiller AL, Schauvinhold I, Larson M, Xu R, Charbonneau AL, Schmidt A, Wilkerson C, Last RL, Pichersky E (2009). "Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate." Proc Natl Acad Sci U S A 106(26);10865-70. PMID: 19487664


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC13A.