Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: NAD-dependent succinate semialdehyde dehydrogenase

Gene: SSR1 Accession Number: G-11940 (MetaCyc)

Species: Solanum lycopersicum

Summary:
A cDNA clone was isolated from fresh leaves of Solanum lycopersicum. The cDNA was recombinantly expresed in E.coli. The expressed protein shares identity with succinic semialdehyde reductase. The enzyme catalyzes the conversion of succinate semialdehyde to succinate using NAD+ [Akihiro08].

Molecular Weight of Polypeptide: 30.4 kD (experimental) [Akihiro08 ]

Unification Links: Entrez-Nucleotide:BAG16485 , Entrez:BAG16485 , Protein Model Portal:B1Q3F6 , UniProt:B1Q3F6

Relationship Links: InterPro:IN-FAMILY:IPR006115 , InterPro:IN-FAMILY:IPR008927 , InterPro:IN-FAMILY:IPR013328 , InterPro:IN-FAMILY:IPR015815 , InterPro:IN-FAMILY:IPR016040 , Panther:IN-FAMILY:PTHR22981 , Pfam:IN-FAMILY:PF03446

Gene-Reaction Schematic: ?

Credits:
Created 31-Mar-2010 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: succinate semialdehyde dehydrogenase

Synonyms: succinic semialdehyde reductase

EC Number: 1.2.1.24

succinate semialdehyde + NAD+ + H2O <=> succinate + NADH + 2 H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

In Pathways: glutamate degradation IV , 4-aminobutyrate degradation , 4-aminobutyrate degradation IV


References

Akihiro08: Akihiro T, Koike S, Tani R, Tominaga T, Watanabe S, Iijima Y, Aoki K, Shibata D, Ashihara H, Matsukura C, Akama K, Fujimura T, Ezura H (2008). "Biochemical mechanism on GABA accumulation during fruit development in tomato." Plant Cell Physiol 49(9);1378-89. PMID: 18713763


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Tue Nov 25, 2014, BIOCYC13A.