MetaCyc Enzyme: citral dehydrogenase

Species: Penicillium digitatum ATCC 201167

The subunit structure of this enzyme has not been reported. The gene encoding it has not been identified in this organism.

Citral is a mixture of the isomers geranial (trans-citral) and neral (cis-citral). Citral dehydrogenase activity in spore extracts was shown to convert geranial to its corresponding acid geranate in an NAD+-dependent manner [Wolken01].

Gene-Reaction Schematic

Gene-Reaction Schematic

Created 07-Jan-2011 by Fulcher CA, SRI International

Enzymatic reaction of: geranial dehydrogenase (citral dehydrogenase)

Inferred from experiment

EC Number:

geranial + NAD+ + H2O ⇄ geranate + NADH + 2 H+

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: geraniol and nerol degradation

The enzyme could not utilize NADP+ as cofactor. Citral, a mixture of geranial and neral was used as substrate. No accululation of neric acid was observed during citral biotransformation [Wolken01].


Wolken01: Wolken WA, van der Werf MJ (2001). "Geraniol biotransformation-pathway in spores of Penicillium digitatum." Appl Microbiol Biotechnol 57(5-6);731-7. PMID: 11778886

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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