Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Enzyme: citral dehydrogenase

Species: Penicillium digitatum ATCC 201167

Summary:
The subunit structure of this enzyme has not been reported. The gene encoding it has not been identified in this organism.

Citral is a mixture of the isomers geranial (trans-citral) and neral (cis-citral). Citral dehydrogenase activity in spore extracts was shown to convert geranial to its corresponding acid geranate in an NAD+-dependent manner [Wolken01].

Gene-Reaction Schematic: ?

Credits:
Created 07-Jan-2011 by Fulcher CA , SRI International


Enzymatic reaction of: geranial dehydrogenase (citral dehydrogenase)

EC Number: 1.2.1.86

geranial + NAD+ + H2O <=> geranate + NADH + 2 H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: geraniol and nerol degradation

Summary:
The enzyme could not utilize NADP+ as cofactor. Citral, a mixture of geranial and neral was used as substrate. No accululation of neric acid was observed during citral biotransformation [Wolken01].


References

Wolken01: Wolken WA, van der Werf MJ (2001). "Geraniol biotransformation-pathway in spores of Penicillium digitatum." Appl Microbiol Biotechnol 57(5-6);731-7. PMID: 11778886


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, biocyc13.