Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: acetyl-CoA:alcohol O-acyltransferase

Gene: AT9 Accession Number: G-12810 (MetaCyc)

Species: Actinidia eriantha

Summary:
A cDNA clone encoding an acetyl-CoA:alcohol O-acyltransferase was isolated from A. deliciosa tissue and recombinantly expressed in yeast. The gene was named AT9.

The recombinant protein was characterized for its substrate specificity, and exhibited alcohol acyl transferase activity (AAT) with a broad range of alcohol and acyl-CoA substrates leading to the formation of volatile esters commonly found in kiwifruit [Gunther11].

Transcript accumulation increased by several folds in ripe versus unripe fruit.

Molecular Weight of Polypeptide: 47.67 kD (from nucleotide sequence)

Unification Links: Entrez-Nucleotide:HO772637

Gene-Reaction Schematic: ?

Credits:
Created 27-Apr-2011 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: acetyl-CoA:butanol O-acyltransferase (acetyl-CoA:alcohol O-acyltransferase)

n-butanol + acetyl-CoA <=> butyl acetate + coenzyme A

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

In Pathways: volatile esters biosynthesis (during fruit ripening)


References

Gunther11: Gunther CS, Chervin C, Marsh KB, Newcomb RD, Souleyre EJ (2011). "Characterisation of two alcohol acyltransferases from kiwifruit (Actinidia spp.) reveals distinct substrate preferences." Phytochemistry 72(8);700-10. PMID: 21450321


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC13B.