MetaCyc Enzyme: galactose-1-phosphate uridylyltransferase

Gene: galT Accession Number: G-183 (MetaCyc)

Species: Thermotoga maritima

Molecular Weight of Polypeptide: 37.633 kD (from nucleotide sequence) [Bairoch93a ]

Unification Links: ModBase:O33836 , Protein Model Portal:O33836 , String:243274.TM1191 , Swiss-Model:O33836 , UniProt:O33836

Relationship Links: InterPro:IN-FAMILY:IPR001937 , InterPro:IN-FAMILY:IPR005849 , InterPro:IN-FAMILY:IPR005850 , InterPro:IN-FAMILY:IPR011146 , InterPro:IN-FAMILY:IPR019779 , Panther:IN-FAMILY:PTHR11943 , Pfam:IN-FAMILY:PF01087 , Pfam:IN-FAMILY:PF02744 , Prosite:IN-FAMILY:PS00117

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Enzymatic reaction of: galactose-1-phosphate uridylyltransferase

Synonyms: UTP-hexose-1-phosphate uridylyltransferase, UTP:α-D-hexose-1-phosphate uridylyltransferase

EC Number:

α-D-galactose 1-phosphate + UTP + H+ <=> UDP-α-D-galactose + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction of enzyme catalysis.

This reaction is reversible.

Galactose-1-phosphate uridylyltransferase is present in Thermotoga maritima. The enzyme is probably involved in the catabolism and utilization of galactoside. [Liebl98, Nelson99]


Bairoch93a: Bairoch A, Boeckmann B (1993). "The SWISS-PROT protein sequence data bank, recent developments." Nucleic Acids Res. 21:3093-3096. PMID: 8332529

Liebl98: Liebl W, Wagner B, Schellhase J (1998). "Properties of an alpha-galactosidase, and structure of its gene galA, within an alpha-and beta-galactoside utilization gene cluster of the hyperthermophilic bacterium Thermotoga maritima." Syst Appl Microbiol 1998;21(1);1-11. PMID: 9741105

Nelson99: Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, Fraser CM (1999). "Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima." Nature 1999;399(6734);323-9. PMID: 10360571

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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