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MetaCyc Polypeptide: SoxE

Gene: soxE Accession Number: G-317 (MetaCyc)

Synonyms: cytochrome c

Species: Paracoccus pantotrophus

Summary:
This is a monoheme cytochrome.

Gene Citations: [Wodara97, Friedrich00]

Locations: periplasmic space

Molecular Weight of Polypeptide: 25.927 kD (from nucleotide sequence)

Unification Links: Protein Model Portal:O33435 , UniProt:O33435

Relationship Links: Entrez-Nucleotide:RELATED-TO:X79242 , InterPro:IN-FAMILY:IPR002327 , InterPro:IN-FAMILY:IPR003088 , InterPro:IN-FAMILY:IPR009056 , Panther:IN-FAMILY:PTHR11961 , Pfam:IN-FAMILY:PF00034 , Prints:IN-FAMILY:PR00604 , Prosite:IN-FAMILY:PS51007

Reactions known to consume the compound:

ammonia oxidation I (aerobic) :
4 an oxidized c-type cytochrome[out] + hydroxylamine[in] + H2O[in] → 4 a reduced c-type cytochrome[out] + nitrite[in] + 5 H+[in]

ammonia oxidation IV (autotrophic ammonia oxidizers) :
a reduced cytochrome c554 + an oxidized c-type cytochrome → an oxidized cytochrome c554 + a reduced c-type cytochrome
4 an oxidized c-type cytochrome[out] + hydroxylamine[in] + H2O[in] → 4 a reduced c-type cytochrome[out] + nitrite[in] + 5 H+[in]

L-ascorbate biosynthesis I (L-galactose pathway) :
L-galactono-1,4-lactone + 2 an oxidized c-type cytochrome → L-ascorbate + 2 a reduced c-type cytochrome + 3 H+

L-ascorbate biosynthesis II (L-gulose pathway) :
L-gulono-1,4-lactone + 2 an oxidized c-type cytochrome → L-ascorbate + 2 a reduced c-type cytochrome + 2 H+

methylglyoxal degradation V :
(S)-lactate + 2 an oxidized c-type cytochrome → pyruvate + 2 a reduced c-type cytochrome + 2 H+

methylglyoxal degradation VI :
(R)-lactate + 2 an oxidized c-type cytochrome → pyruvate + 2 a reduced c-type cytochrome + 2 H+

nitrifier denitrification :
hydroxylamine + an oxidized c-type cytochrome → nitric oxide + a reduced c-type cytochrome + 3 H+

nitrite oxidation :
2 a reduced c-type cytochrome[out] + nitrate[in] + 2 H+[in] ← 2 an oxidized c-type cytochrome[out] + nitrite[in] + H2O[in]

polyvinyl alcohol degradation :
polyvinyl alcohol + n an oxidized c-type cytochrome → oxidized polyvinyl alcohol + n a reduced c-type cytochrome + n H+

sulfide oxidation II (sulfide dehydrogenase) :
hydrogen sulfide + 2 an oxidized c-type cytochrome → S0 + 2 a reduced c-type cytochrome + 2 H+

sulfite oxidation I (sulfite oxidoreductase) :
sulfite + 2 an oxidized c-type cytochrome + H2O → sulfate + 2 a reduced c-type cytochrome + 2 H+

thiosulfate oxidation I (to tetrathionate) :
2 thiosulfate[periplasmic space] + 4 an oxidized c-type cytochrome[periplasmic space] → tetrathionate[periplasmic space] + 4 a reduced c-type cytochrome[periplasmic space] + 2 H+[periplasmic space]

thiosulfate oxidation III (multienzyme complex) :
a [SoxY protein]-L-cysteine + thiosulfate + 2 an oxidized c-type cytochrome → a [SoxY protein]-thiocysteine-S-sulfate + 2 a reduced c-type cytochrome + 2 H+
a [SoxY protein]-S-thiocysteine + 6 an oxidized c-type cytochrome + 3 H2O → a [SoxY protein]-L-cysteine-S-sulfate + 6 a reduced c-type cytochrome + 7 H+

thiosulfate oxidation IV (multienzyme complex) :
a [SoxY protein]-L-cysteine + thiosulfate + 2 an oxidized c-type cytochrome → a [SoxY protein]-thiocysteine-S-sulfate + 2 a reduced c-type cytochrome + 2 H+

Not in pathways:
L-ascorbate + 2 an oxidized c-type cytochrome → L-dehydro-ascorbate + 2 a reduced c-type cytochrome + H+
2 an oxidized c-type cytochrome[out] + an electron-transfer-related quinol → 2 a reduced c-type cytochrome[out] + an electron-transfer-related quinone + 2 H+[in]
2 an oxidized c-type cytochrome[out] + a menaquinol → 2 a reduced c-type cytochrome[out] + a menaquinone + 2 H+[in]
hydroxylamine + 4 an oxidized c-type cytochrome + oxygen → nitrite + 4 a reduced c-type cytochrome + H2O + H+

nicotinate degradation I :
nicotinate + an oxidized cytochrome + H2O → 6-hydroxynicotinate + a reduced cytochrome + 2 H+

Reactions known to produce the compound:

aerobic respiration I (cytochrome c) , aerobic respiration II (cytochrome c) (yeast) , arsenite oxidation I (respiratory) :
4 a reduced c-type cytochrome[out] + oxygen[in] + 8 H+[in] → 4 an oxidized c-type cytochrome[out] + 4 H+[out] + 2 H2O[in]

ammonia oxidation II (anaerobic) , intra-aerobic nitrite reduction :
nitric oxide + an oxidized c-type cytochrome + H2O ← nitrite + a reduced c-type cytochrome + 2 H+

nitrate reduction I (denitrification) :
2 a reduced c-type cytochrome[periplasmic space] + nitrous oxide + 2 H+ → 2 an oxidized c-type cytochrome[periplasmic space] + N2 + H2O

nitrate reduction IV (dissimilatory) :
ammonia + 6 an oxidized c-type cytochrome + 2 H2O ← nitrite + 6 a reduced c-type cytochrome + 7 H+
2 a reduced c-type cytochrome[out] + nitrate[in] + 2 H+[in] → 2 an oxidized c-type cytochrome[out] + nitrite[in] + H2O[in]

nitrate reduction VII (denitrification) :
nitric oxide + an oxidized c-type cytochrome + H2O ← nitrite + a reduced c-type cytochrome + 2 H+
2 a reduced c-type cytochrome[periplasmic space] + nitrous oxide + 2 H+ → 2 an oxidized c-type cytochrome[periplasmic space] + N2 + H2O

nitrifier denitrification :
nitric oxide + an oxidized c-type cytochrome + H2O ← nitrite + a reduced c-type cytochrome + 2 H+
2 a reduced c-type cytochrome[periplasmic space] + nitrous oxide + 2 H+ → 2 an oxidized c-type cytochrome[periplasmic space] + N2 + H2O

Reactions known to both consume and produce the compound:

aerobic respiration I (cytochrome c) , aerobic respiration II (cytochrome c) (yeast) , ammonia oxidation IV (autotrophic ammonia oxidizers) :
2 an oxidized c-type cytochrome[out] + an ubiquinol[CCO-OUT-CCO-IN] + 2 H+[in] ↔ 2 a reduced c-type cytochrome[out] + an ubiquinone[CCO-OUT-CCO-IN] + 4 H+[in]

arsenite oxidation I (respiratory) :
2 a reduced c-type cytochrome[periplasmic space] + arsenate + 3 H+ ← 2 an oxidized c-type cytochrome[periplasmic space] + arsenite + H2O

nitrate reduction I (denitrification) , nitrifier denitrification :
nitrous oxide + 2 an oxidized c-type cytochrome + H2O ↔ 2 nitric oxide + 2 a reduced c-type cytochrome + 2 H+

Not in pathways:
a c-type cytochrome ↔ heme c + an apo c-type cytochrome

In Reactions of unknown directionality:

Not in pathways:
L-galactono-1,4-lactone + 4 an oxidized c-type cytochrome = L-dehydro-ascorbate + 4 a reduced c-type cytochrome + 4 H+
lupanine + 2 an oxidized c-type cytochrome + H2O = 17-hydroxylupanine + 2 a reduced c-type cytochrome + 2 H+
L-gulono-1,4-lactone + 4 an oxidized c-type cytochrome = L-dehydro-ascorbate + 4 a reduced c-type cytochrome + 4 H+
D-mannitol + an oxidized c-type cytochrome = keto-D-fructose + a reduced c-type cytochrome + 2 H+
ethanol + 2 an oxidized c-type cytochrome = acetaldehyde + 2 a reduced c-type cytochrome + 2 H+
trimethylamine + 2 an oxidized c-type cytochrome + H2O = trimethylamine N-oxide + 2 a reduced c-type cytochrome + 3 H+
2 an oxidized c-type cytochrome + glycine + H2O = 2 a reduced c-type cytochrome + ammonium + glyoxylate + 2 H+
hydrogen peroxide + 2 a reduced c-type cytochrome + 2 H+ = 2 an oxidized c-type cytochrome + 2 H2O
Fe3+ + a reduced c-type cytochrome = Fe2+ + an oxidized c-type cytochrome

In Redox half-reactions:
an oxidized c-type cytochrome[out] + e- → a reduced c-type cytochrome[out]

GO Terms:

Cellular Component: GO:0030288 - outer membrane-bounded periplasmic space

Credits:
Created 11-Aug-1999 by Pellegrini-Toole A , Marine Biological Laboratory
Revised 31-Aug-2006 by Caspi R , SRI International


References

Friedrich00: Friedrich CG, Quentmeier A, Bardischewsky F, Rother D, Kraft R, Kostka S, Prinz H (2000). "Novel genes coding for lithotrophic sulfur oxidation of Paracoccus pantotrophus GB17." J Bacteriol 182(17);4677-87. PMID: 10940005

Wodara97: Wodara C, Bardischewsky F, Friedrich CG (1997). "Cloning and characterization of sulfite dehydrogenase, two c-type cytochromes, and a flavoprotein of Paracoccus denitrificans GB17: essential role of sulfite dehydrogenase in lithotrophic sulfur oxidation." J Bacteriol 1997;179(16);5014-23. PMID: 9260941


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC13A.